Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction5'-3' DNA helicase activity

DDX11L8 HELB DDX11

4.85e-0611633GO:0043139
GeneOntologyMolecularFunctiontriplex DNA binding

DDX11L8 DDX11

5.85e-054632GO:0045142
DomainAtg8

MAP1LC3B2 MAP1LC3B

3.09e-048632PF02991
DomainAtg8-like

MAP1LC3B2 MAP1LC3B

3.09e-048632IPR004241
DomainA2M_N

A2M PZP

4.95e-0410632PF01835
DomainA2M_N

A2M PZP

4.95e-0410632IPR002890
DomainA-macroglobulin_rcpt-bd

A2M PZP

4.95e-0410632IPR009048
DomainALPHA_2_MACROGLOBULIN

A2M PZP

4.95e-0410632PS00477
DomainA2M

A2M PZP

4.95e-0410632PF00207
DomainA2M_N_2

A2M PZP

4.95e-0410632IPR011625
DomainA2M_comp

A2M PZP

4.95e-0410632IPR011626
DomainA2M_N_2

A2M PZP

4.95e-0410632PF07703
DomainA2M_recep

A2M PZP

4.95e-0410632PF07677
DomainA2M_comp

A2M PZP

4.95e-0410632PF07678
DomainMacroglobln_a2

A2M PZP

4.95e-0410632IPR001599
DomainTyr_kinase_rcpt_2_CS

NTRK3 ROS1

6.04e-0411632IPR002011
DomainRECEPTOR_TYR_KIN_II

NTRK3 ROS1

7.23e-0412632PS00239
DomainLRR_1

LRRN1 NTRK3 LRRC40 OMG FBXL5

8.57e-04219635PF00560
DomainARM-type_fold

SCYL2 TRPC4AP DOCK11 MTOR DIAPH2 APOB

9.74e-04339636IPR016024
DomainTerpenoid_cyclase/PrenylTrfase

A2M PZP

1.65e-0318632IPR008930
DomainLeu-rich_rpt

LRRN1 NTRK3 LRRC40 OMG FBXL5

2.19e-03271635IPR001611
DomainLRR_8

LRRN1 NTRK3 LRRC40 OMG

2.65e-03171634PF13855
DomainLRRNT

LRRN1 NTRK3 OMG

4.43e-0398633IPR000372
DomainLRRNT

LRRN1 NTRK3 OMG

4.43e-0398633SM00013
Domain-

LRRN1 NTRK3 LRRC40 OMG FBXL5

4.53e-033216353.80.10.10
DomainLRR

LRRN1 NTRK3 LRRC40 OMG

4.73e-03201634PS51450
DomainL_dom-like

LRRN1 NTRK3 LRRC40 OMG FBXL5

4.96e-03328635IPR032675
DomainSulfotransferase_dom

NDST4 DSEL

6.55e-0336632IPR000863
DomainSulfotransfer_1

NDST4 DSEL

6.55e-0336632PF00685
Pubmed

Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.

MAP1LC3B2 NTRK3 MAP1LC3B SMAD2

3.96e-081964421957238
Pubmed

Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism.

MAP1LC3B2 MTOR MAP1LC3B

9.70e-071164330704899
Pubmed

Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes.

MAP1LC3B2 MTOR MAP1LC3B

2.13e-061464339245708
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

A2M RINT1 CEP85 DIAPH2 POLRMT DLG1 PZP INTS3 DDX11L8

2.90e-0665064938777146
Pubmed

Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.

MAP1LC3B2 MAP1LC3B

3.33e-06264225421500
Pubmed

Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.

MAP1LC3B2 MAP1LC3B

3.33e-06264227265145
Pubmed

USP32 promotes tumorigenesis and chemoresistance in gastric carcinoma via upregulation of SMAD2.

USP32 SMAD2

3.33e-06264232226309
Pubmed

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.

MAP1LC3B2 MAP1LC3B

3.33e-06264220889906
Pubmed

A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region. Genomic structure of the bait domains of human pregnancy zone protein and alpha 2 macroglobulin.

A2M PZP

3.33e-0626421692292
Pubmed

Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.

MAP1LC3B2 MAP1LC3B

3.33e-06264238656870
Pubmed

Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons.

MAP1LC3B2 MAP1LC3B

3.33e-06264212088839
Pubmed

Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.

MAP1LC3B2 MAP1LC3B

3.33e-06264222968077
Pubmed

Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation.

MTOR APOB

3.33e-06264217698027
Pubmed

[Preparation of an autophagy-targeted antituberculosis DNA vaccine encoding LpqH fused with LC3].

MAP1LC3B2 MAP1LC3B

3.33e-06264224909277
Pubmed

Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells.

MAP1LC3B2 MAP1LC3B

3.33e-06264228928467
Pubmed

Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice.

MAP1LC3B2 MAP1LC3B

3.33e-06264237047689
Pubmed

Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation.

MAP1LC3B2 MAP1LC3B

3.33e-06264232057231
Pubmed

Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.

MAP1LC3B2 MAP1LC3B

3.33e-06264230349463
Pubmed

Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.

MAP1LC3B2 MAP1LC3B

3.33e-06264231431059
Pubmed

Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.

MTOR ROS1

3.33e-06264231053160
Pubmed

Differential binding properties of human pregnancy zone protein- and alpha2-macroglobulin-proteinase complexes to low-density lipoprotein receptor-related protein.

A2M PZP

3.33e-06264211811950
Pubmed

Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).

MAP1LC3B2 MAP1LC3B

3.33e-06264231577510
Pubmed

LC3 conjugation system in mammalian autophagy.

MAP1LC3B2 MAP1LC3B

3.33e-06264215325588
Pubmed

LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy.

MAP1LC3B2 MAP1LC3B

3.33e-06264237315562
Pubmed

EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy.

MAP1LC3B2 MTOR MAP1LC3B

3.97e-061764326905199
Pubmed

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.

MAP1LC3B2 MTOR MAP1LC3B

5.64e-061964327246713
Pubmed

ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.

MAP1LC3B2 MTOR MAP1LC3B

7.72e-062164330985297
Pubmed

Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth.

MAP1LC3B2 MTOR MAP1LC3B

8.93e-062264327798115
Pubmed

SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.

MAP1LC3B2 MTOR MAP1LC3B

8.93e-062264334037656
Pubmed

The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif.

MAP1LC3B2 MAP1LC3B

9.99e-06364228291748
Pubmed

Activated Akt/mTOR-autophagy in local T cells of oral lichen planus.

MTOR MAP1LC3B

9.99e-06364228482233
Pubmed

Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.

MAP1LC3B2 MAP1LC3B

9.99e-06364227636016
Pubmed

Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.

MAP1LC3B2 MAP1LC3B

9.99e-06364228598240
Pubmed

Autophagy plays an essential role in cigarette smoke-induced expression of MUC5AC in airway epithelium.

MAP1LC3B2 MAP1LC3B

9.99e-06364227036871
Pubmed

Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

DDX11L8 DDX11

9.99e-06364217611414
Pubmed

Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin.

A2M PZP

9.99e-06364212183561
Pubmed

Alpha-2 macroglobulin controls trophoblast positioning in mouse implantation sites.

A2M PZP

9.99e-06364214580373
Pubmed

Microtubule-Associated Protein 1 Light Chain 3 (LC3) Isoforms in RPE and Retina.

MAP1LC3B2 MAP1LC3B

9.99e-06364229721994
Pubmed

HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide.

MAP1LC3B2 MAP1LC3B

9.99e-06364229088262
Pubmed

Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes.

MAP1LC3B2 MAP1LC3B

9.99e-06364224095928
Pubmed

ALK, ROS1 and NTRK3 gene rearrangements in inflammatory myofibroblastic tumours.

NTRK3 ROS1

9.99e-06364226647767
Pubmed

Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.

A2M PZP

9.99e-0636428662763
Pubmed

Mammalian ChlR1 has a role in heterochromatin organization.

DDX11L8 DDX11

9.99e-06364221854770
Pubmed

alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.

A2M PZP

9.99e-06364210487856
Pubmed

Autophagy proteins are modulated in the liver and hypothalamus of the offspring of mice with diet-induced obesity.

MAP1LC3B2 MAP1LC3B

9.99e-06364227180121
Pubmed

TGF-beta enhances the integrin alpha2beta1-mediated attachment of mesenchymal stem cells to type I collagen.

ITGA2 SMAD2

9.99e-06364219827952
Pubmed

ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.

MAP1LC3B2 MAP1LC3B

9.99e-06364233459130
Pubmed

BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.

MAP1LC3B2 MAP1LC3B

9.99e-06364233459136
Pubmed

Autophagy is required and protects against apoptosis during myoblast differentiation.

MAP1LC3B2 MAP1LC3B

9.99e-06364224865278
Pubmed

Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.

MAP1LC3B2 MAP1LC3B

9.99e-06364218069693
Pubmed

BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.

MAP1LC3B2 MAP1LC3B

9.99e-06364224591579
Pubmed

Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation.

MAP1LC3B2 MTOR MAP1LC3B

1.88e-052864332744119
Pubmed

p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.

MAP1LC3B2 MAP1LC3B

2.00e-05464230941888
Pubmed

Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death.

MAP1LC3B2 MAP1LC3B

2.00e-05464222095627
Pubmed

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.

MAP1LC3B2 MAP1LC3B

2.00e-05464232376415
Pubmed

Interaction of matrix metalloproteinases-2 and -9 with pregnancy zone protein and alpha2-macroglobulin.

A2M PZP

2.00e-0546429344465
Pubmed

Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin.

MAP1LC3B2 MAP1LC3B

2.00e-05464225816775
Pubmed

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.

A2M PZP

2.00e-05464227031383
Pubmed

STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain.

MAP1LC3B2 MAP1LC3B

2.00e-05464233201170
Pubmed

The Hedgehog signalling pathway regulates autophagy.

MAP1LC3B2 MAP1LC3B

2.00e-05464223149744
Pubmed

MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.

MAP1LC3B2 MAP1LC3B

2.00e-05464226719147
Pubmed

The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.

MAP1LC3B2 MAP1LC3B

2.00e-05464225301234
Pubmed

Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.

MAP1LC3B2 MAP1LC3B

2.00e-05464232372061
Pubmed

Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1.

MAP1LC3B2 MAP1LC3B

2.00e-05464225669150
Pubmed

Aging is associated with hypermethylation of autophagy genes in macrophages.

MAP1LC3B2 MAP1LC3B

2.00e-05464226909551
Pubmed

Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro.

MAP1LC3B2 MAP1LC3B

2.00e-05464221681844
Pubmed

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.

MAP1LC3B2 MAP1LC3B

2.00e-05464224200693
Pubmed

The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.

MAP1LC3B2 MAP1LC3B

2.00e-05464218768753
Pubmed

Hepatocellular carcinoma-related cyclin D1 is selectively regulated by autophagy degradation system.

MAP1LC3B2 MAP1LC3B

2.00e-05464229328502
Pubmed

Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts.

MAP1LC3B2 MAP1LC3B

2.00e-05464234706731
Pubmed

Acetylation modulates LC3 stability and cargo recognition.

MAP1LC3B2 MAP1LC3B

2.00e-05464230633346
Pubmed

Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway.

MAP1LC3B2 MAP1LC3B

2.00e-05464222055190
Pubmed

Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.

MAP1LC3B2 MAP1LC3B

2.00e-05464219915056
Pubmed

Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors.

A2M PZP

2.00e-0546421702714
Pubmed

Autophagy exacerbates electrical remodeling in atrial fibrillation by ubiquitin-dependent degradation of L-type calcium channel.

MAP1LC3B2 MAP1LC3B

2.00e-05464230158642
Pubmed

Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.

MAP1LC3B2 MAP1LC3B SMAD2

3.12e-053364333436499
Pubmed

Autophagy prior to chondrocyte cell death during the degeneration of Meckel's cartilage.

MAP1LC3B2 MAP1LC3B

3.32e-05564222371349
Pubmed

CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation.

MAP1LC3B2 MAP1LC3B

3.32e-05564224566975
Pubmed

In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11.

MAP1LC3B2 MAP1LC3B

3.32e-05564226284655
Pubmed

Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues.

A2M PZP

3.32e-0556427514554
Pubmed

Autophagy proteins are required for club cell structure and function in airways.

MAP1LC3B2 MAP1LC3B

3.32e-05564231116580
Pubmed

Human CLEC16A regulates autophagy through modulating mTOR activity.

MTOR MAP1LC3B

3.32e-05564228223137
Pubmed

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.

MAP1LC3B2 MAP1LC3B

3.32e-05564222863802
Pubmed

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.

MAP1LC3B2 MAP1LC3B

3.32e-05564221151103
Pubmed

Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes.

MTOR MAP1LC3B

3.32e-05564225339774
Pubmed

Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex.

MAP1LC3B2 MAP1LC3B

3.32e-05564225227738
Pubmed

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells.

MAP1LC3B2 MAP1LC3B

3.32e-05564228916785
Pubmed

Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1.

MAP1LC3B2 MAP1LC3B

3.32e-05564229937374
Pubmed

mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.

MAP1LC3B2 MTOR MAP1LC3B

3.41e-053464332866472
Pubmed

Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.

MAP1LC3B2 MAP1LC3B SMAD2

4.79e-053864322783020
Pubmed

Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.

MAP1LC3B2 MAP1LC3B

4.98e-05664234524943
Pubmed

The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression.

MTOR PKN2

4.98e-05664228875501
Pubmed

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

MAP1LC3B2 MAP1LC3B

4.98e-05664224747438
Pubmed

Suppressor of Cytokine Signaling 2 Regulates Retinal Pigment Epithelium Metabolism by Enhancing Autophagy.

MTOR MAP1LC3B

4.98e-05664234819832
Pubmed

Autophagy appears during the development of the mouse lower first molar.

MAP1LC3B2 MAP1LC3B

4.98e-05664223052835
Pubmed

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.

MAP1LC3B2 MAP1LC3B

4.98e-05664222138575
Pubmed

p62 sequestosome 1/light chain 3b complex confers cytoprotection on lung epithelial cells after hyperoxia.

MAP1LC3B2 MAP1LC3B

4.98e-05664223333919
Pubmed

Autophagy proteins regulate the secretory component of osteoclastic bone resorption.

MAP1LC3B2 MAP1LC3B

4.98e-05664222055344
Pubmed

Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1-/-(yotari) Mice.

MAP1LC3B2 MAP1LC3B

4.98e-05664236979337
Pubmed

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.

MAP1LC3B2 MAP1LC3B

4.98e-05664221383079
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M PZP

1.70e-0494021234
GeneFamilyAutophagy related

MAP1LC3B2 MAP1LC3B

2.41e-03334021022
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK3 ROS1

3.53e-0340402321
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 ODAD1 TSPAN19 PZP OMG

3.88e-061646450e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-late_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAP1LC3B2 SPTB MAP1LC3B RAD23A

5.51e-05144644ca365380ccf5e60d2e3f6272059ff0531759612d
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 NDST4 ROS1 CRB1

5.66e-0514564496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellASK452-Epithelial-Type_2|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

RAET1E ROS1 HELB DDX11

7.51e-05156644e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Ptgds_(Ptgds)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SERPINE3 C12orf71 CLTRN

8.01e-055864392afa343d2e80ea076533ab2e45f63a4638f37aa
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Ptgds_(Ptgds)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SERPINE3 C12orf71 CLTRN

8.01e-0558643f840029b1fcca7570aa836eded41dc33ca5aa0a6
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD42 CEP85 SPTB PZP

8.49e-0516164460f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 NTRK3 NDST4 ROS1

8.70e-05162644bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 ODAD1 TSPAN19 PZP

1.02e-0416964414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB MAP1LC3B CRB1 RAD23A

1.10e-04172644cc1a45a35f78063b2a777ae905f70f894fbcb22f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB MAP1LC3B CRB1 RAD23A

1.10e-0417264430c57f5ca2326e8d890d9aac8096c64e5b51a24f
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINE3 RAET1E HERC6 CRB1

1.10e-04172644c84cab89c97d647b8a256fd08e33d9102810febd
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CLTRN NDST4 ST8SIA3

1.22e-041776441dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CLTRN NDST4 ST8SIA3

1.22e-04177644426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 ODAD1 TSPAN19 RAET1E

1.25e-041786443b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ODAD1 TSPAN19 PZP OMG

1.28e-041796440e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellT_cells-GZMK+_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

A2M TTC24 EXOC2 PZP

1.28e-04179644798f208014f2229c597934775646ddbbacf94b69
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SERPINE3 ITGA2 PZP

1.29e-0468643ad6c363d7fb3c436e894db30a544748c5df75a45
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SERPINE3 ITGA2 PZP

1.29e-046864382d928f5eefa065d26096a84b0d78f131dcc8c73
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SERPINE3 ITGA2 PZP

1.29e-0468643d97199a8c6afa79bff1600f00c2dbf6286df24a2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ABCA13 ROS1 APOB

1.42e-04184644ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ABCA13 ROS1 APOB

1.42e-041846442cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ABCA13 ROS1 APOB

1.42e-041846442b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 ODAD1 TSPAN19 OMG

1.45e-041856444fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CLTRN NDST4 ST8SIA3

1.48e-041866444bb54043f944a979db91bde9a86dd66f498c7658
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ODAD1 TSPAN19 PZP OMG

1.51e-041876442b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

A2M PKN2 ITGA2 OMG

1.61e-0419064471e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 ODAD1 TSPAN19 OMG

1.61e-0419064417829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 ODAD1 TSPAN19 OMG

1.64e-041916442a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 ODAD1 TSPAN19 OMG

1.64e-041916442d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 ODAD1 TSPAN19 OMG

1.64e-0419164446c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

ABCA13 ODAD1 TSPAN19 OMG

1.64e-04191644ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ABCA13 ODAD1 TSPAN19 OMG

1.64e-04191644995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 ODAD1 TSPAN19 OMG

1.64e-04191644a37f20172b85566b9039254a89680e37fd503fd5
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

ABCA13 ODAD1 TSPAN19 OMG

1.64e-041916446228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA13 TSPAN19 PZP OMG

1.67e-0419264403acd4a26b986e34eee608747347791122f1aa52
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

ABCA13 ODAD1 TSPAN19 OMG

1.67e-041926449cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA13 TSPAN19 PZP OMG

1.67e-0419264431c6046589e2fbb0486fd044c5b128099d37872f
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 ODAD1 ITGA2 PZP

1.71e-04193644ea345d34440b25f65358a53dc72831998d1c3620
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ABCA13 ODAD1 TSPAN19 OMG

1.74e-0419464443be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1LC3B2 NTRK3 TSPAN19 THAP9

1.77e-04195644a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCA13 ODAD1 TSPAN19 OMG

1.77e-0419564434e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 DIAPH2 TSPAN19 OMG

1.84e-0419764471fea4aa6ce96c7693fa94792d08770622873850
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M TTC14 PZP HELB

1.84e-04197644e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 DIAPH2 TSPAN19 OMG

1.84e-04197644d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 DIAPH2 TSPAN19 OMG

1.84e-04197644e453d085182364ca347cbcc9dc995c62c3353016
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC4AP LRRN1 OMG FBXL5

1.88e-04198644a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 ODAD1 TSPAN19 OMG

1.95e-04200644f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA13 ODAD1 TSPAN19 OMG

1.95e-04200644d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 TSPAN19 PZP OMG

1.95e-0420064412bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ABCA13 ODAD1 TSPAN19 OMG

1.95e-04200644f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 TSPAN19 PZP OMG

1.95e-0420064431d75c26055177d656df1fbb10b764cebd61e122
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 TSPAN19 PZP OMG

1.95e-0420064485c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 TSPAN19 PZP OMG

1.95e-04200644e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 ODAD1 TSPAN19 OMG

1.95e-04200644cf59110547cc66b5f4a2999735336b0309ba9b0d
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX11L8 DDX11

1.26e-053612DOID:0060535 (implicated_via_orthology)
DiseaseLarge cell carcinoma of lung

MTOR NTRK3 ROS1

4.00e-0532613C0345958
Diseasesuntan

CYP1B1 TRPC4AP EXOC2 CRB1

6.27e-05103614EFO_0004279
Diseasememory performance

MTERF1 NTRK3 DIAPH2 TSPAN19 EXOC2 DSEL

1.99e-04409616EFO_0004874
DiseaseColorectal Carcinoma

CYP1B1 ABCA13 CCDC62 APOB DSEL PZP SMAD2

5.99e-04702617C0009402
Diseasecerebral infarction (is_marker_for)

A2M APOB

7.03e-0419612DOID:3526 (is_marker_for)
Diseasesciatic neuropathy (implicated_via_orthology)

MTOR HRH3

1.03e-0323612DOID:11446 (implicated_via_orthology)
Diseasenephrotic syndrome (biomarker_via_orthology)

A2M APOB

1.13e-0324612DOID:1184 (biomarker_via_orthology)
Diseaseunipolar depression, depressive symptom measurement

FNIP2 SORCS3

1.32e-0326612EFO_0003761, EFO_0007006
Diseaselipoprotein A measurement

SERPINE3 APOB CLEC4M

1.63e-03112613EFO_0006925
Diseasecomplement factor H-related protein 2 measurement

CRB1 DDX11

1.65e-0329612EFO_0600055
Diseasearteriosclerosis (is_implicated_in)

APOB ITGA2

1.88e-0331612DOID:2349 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LQFLNFNVENSQELI

CCDC62

296

Q6P9F0
FQSNLFQALIDIQEF

DLG1

41

Q12959
FQDAELLQIQALFQR

AVPI1

31

Q5T686
QQLLSIFNFLELQAQ

ABCA13

1031

Q86UQ4
NNFRTLFLEAVRENN

DIAPH2

996

O60879
FSSKFQVDNNNRLLL

A2M

1286

P01023
DLAQRFFKQNILQFI

ANKRD42

206

Q8N9B4
EAQVFLNKNLFLQYN

RAET1E

51

Q8TD07
KNENLAANFLLSQNF

RAD23A

346

P54725
TFSTNFQVDNNNLLL

PZP

1291

P20742
LRLNLTNTKQNFFSQ

INTS3

931

Q68E01
LQLNANQAFFLLVNG

MAP1LC3B

71

Q9GZQ8
IQQNFQRSAFLATFL

HSFY1

146

Q96LI6
FLANFIAAQNILQIQ

MGAM2

1721

Q2M2H8
SLRELQLEQNFFNCS

NTRK3

151

Q16288
RNALNVLQRFKFLFN

EXOC2

271

Q96KP1
ENTFNINELSNLLNF

HERC6

581

Q8IVU3
TQNLLRTQVANFTFN

NDST4

331

Q9H3R1
FLFQSQIDNINLFKV

DDX11

481

Q96FC9
DFNLQNLQNQASLSF

ITGA2

896

P17301
RNFAEFNFINEQNLE

ODAD1

296

Q96M63
LEVLNFDFQANAQLS

APOB

2801

P04114
RFQESLFIINNFANS

DOCK11

1546

Q5JSL3
FLRFLIRHTNQQDQF

CERK

431

Q8TCT0
FTLLIEQINKNQFFA

FNIP2

421

Q9P278
LFFLEQNNRIFQTLL

DENND11

391

A4D1U4
ELQRENTFLRAQFAQ

CEP85

386

Q6P2H3
NDFLFQSQIDNINLF

DDX11L8

481

A8MPP1
RTQNNFFLLNLAISD

HRH3

66

Q9Y5N1
FEQLNRNFSNFILDK

CYP1B1

261

Q16678
KTNFSNNNDFRALLQ

FBXL5

31

Q9UKA1
RLDVQLQFCFFRENQ

FCRL2

136

Q96LA5
CIQDVRLNNQNLEFF

CRB1

851

P82279
QAQLSGQQQRLLAFF

POLRMT

216

O00411
VFLAQRHFNINNLDN

DSEL

291

Q8IZU8
NNLQNAKTSQFIAFR

HELB

731

Q8NG08
LQKLTFLDLRNNFLN

LRRC40

471

Q9H9A6
LQQLFNLTELDFSQN

LRRN1

91

Q6UXK5
FEGNKQRDFNQNFIL

NXT1

101

Q9UKK6
ENLQALFVALNDQVF

MTOR

691

P42345
NFDQQQLANFCRILA

TRPC4AP

236

Q8TEL6
VETLFNALNQNLVQF

SORCS3

1081

Q9UPU3
NLLTIQDRNNFFLSL

ST8SIA3

221

O43173
NNLNLNQFNSFISVI

SCYL2

581

Q6P3W7
LEDRRSQQRFQFNLQ

PKN2

641

Q16513
NIEANFIKPNFQQLF

STYX

66

Q8WUJ0
FDQLFQLQEITLYNN

OMG

211

P23515
EQNFLQLQTSRSNRF

CLEC4M

311

Q9H2X3
LNNLVQEFQIFLENL

C12orf71

131

A8MTZ7
RINNAFFLNDQTLEF

CLTRN

111

Q9HBJ8
KFLFQRQNLACFLTN

C11orf1

11

Q9H5F2
LNQFLLDLKQSLNQF

UHRF1BP1L

541

A0JNW5
QNHEALNNFQRAFLL

TTC24

51

A2A3L6
LQLNANQAFFLLVNG

MAP1LC3B2

71

A6NCE7
NVFFLQLQQAALEVF

RINT1

556

Q6NUQ1
LIRNAFQNFQSIQFI

THAP9

421

Q9H5L6
NLKIFNNQEFAALLA

SMAD2

381

Q15796
SFFRSNNNLNLENNI

MTERF1

166

Q99551
QNFFRQQTESLLQLL

SENP8

176

Q96LD8
FRIQNQFNLKSILNS

SERPINE3

301

A8MV23
LPQNLLNIFNQIAEF

TTC14

746

Q96N46
IQDQLQLFRNFFLNS

ROS1

2211

P08922
SQLQAFLQDLDDFQA

SPTB

1061

P11277
STQVNFLNRALDIFN

NIPAL4

276

Q0D2K0
LLDRNNFLTAFDENN

TSPAN19

36

P0C672
FQQQDSQELLAFLLD

USP32

821

Q8NFA0