Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

2.84e-053622GO:0018858
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

5.67e-054622GO:0102391
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIK3CG PIK3R1 PI4KA

7.04e-0526623GO:0052742
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

MAK NUAK1 PIK3CG PIK3R1 PI4KA PARP2 PKN2 POLQ ERN2 GK5 MAP3K3

1.31e-049386211GO:0016772
GeneOntologyMolecularFunctionligase activity

RCL1 CPS1 ACSM2A PCCA ACSM2B

2.05e-04174625GO:0016874
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM2A ACSM2B

2.62e-048622GO:0004321
GeneOntologyMolecularFunctionlipid kinase activity

PIK3CG PIK3R1 PI4KA

2.79e-0441623GO:0001727
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

MAK NUAK1 PIK3CG PIK3R1 PI4KA PKN2 ERN2 GK5 MAP3K3

3.21e-04709629GO:0016773
GeneOntologyMolecularFunctionmedium-chain fatty acid-CoA ligase activity

ACSM2A ACSM2B

5.12e-0411622GO:0031956
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3CG PIK3R1

5.12e-0411622GO:0016303
GeneOntologyMolecularFunctionkinase activity

MAK NUAK1 PIK3CG PIK3R1 PI4KA PKN2 ERN2 GK5 MAP3K3

5.52e-04764629GO:0016301
GeneOntologyMolecularFunctionprotein serine kinase activity

MAK NUAK1 PIK3CG PKN2 ERN2 MAP3K3

9.03e-04363626GO:0106310
GeneOntologyMolecularFunctionpolypeptide N-acetylgalactosaminyltransferase activity

GALNT10 GALNT4

1.74e-0320622GO:0004653
GeneOntologyMolecularFunctionC-acyltransferase activity

ACSM2A ACSM2B

1.92e-0321622GO:0016408
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

MAK NUAK1 PIK3CG PKN2 ERN2 MAP3K3

2.57e-03446626GO:0004674
GeneOntologyMolecularFunctionATP-dependent activity

STARD9 ATP13A5 FANCM POLQ ACSM2A KIF25 ACSM2B

2.85e-03614627GO:0140657
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSM2A ACSM2B

2.94e-0326622GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSM2A ACSM2B

3.17e-0327622GO:0016405
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class I

PIK3CG PIK3R1

3.17e-049632GO:0097651
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class IA

PIK3CG PIK3R1

3.17e-049632GO:0005943
DomainCPSASE_1

CPS1 PCCA

1.04e-045612PS00866
DomainCPSASE_2

CPS1 PCCA

1.56e-046612PS00867
DomainCPSase_L_D2

CPS1 PCCA

2.18e-047612PF02786
DomainCbamoylP_synth_lsu-like_ATP-bd

CPS1 PCCA

2.18e-047612IPR005479
DomainBC-like_N

CPS1 PCCA

2.18e-047612IPR005481
DomainBiotin_carb_N

CPS1 PCCA

2.18e-047612PF00289
DomainPI3Ka

PIK3CG PI4KA

3.72e-049612PF00613
Domain-

PIK3CG PI4KA

3.72e-0496121.25.40.70
DomainPI3Ka

PIK3CG PI4KA

3.72e-049612SM00145
DomainPIK_HELICAL

PIK3CG PI4KA

4.64e-0410612PS51545
DomainPI_Kinase

PIK3CG PI4KA

4.64e-0410612IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3CG PI4KA

4.64e-0410612IPR001263
DomainFAD-dep_OxRdtase

PDPR KMO

6.78e-0412612IPR006076
DomainDAO

PDPR KMO

6.78e-0412612PF01266
Domain-

CPS1 PCCA

8.00e-04136123.40.50.20
DomainATP-grasp

CPS1 PCCA

9.31e-0414612IPR011761
DomainPreATP-grasp_dom

CPS1 PCCA

9.31e-0414612IPR016185
DomainATP_GRASP

CPS1 PCCA

9.31e-0414612PS50975
DomainPI3/4_kinase_CS

PIK3CG PI4KA

1.07e-0315612IPR018936
Domain-

CPS1 PCCA

1.07e-03156123.30.1490.20
Domain-

PIK3CG PI4KA

1.22e-03166121.10.1070.11
DomainPI3Kc

PIK3CG PI4KA

1.22e-0316612SM00146
DomainAMP-bd_C

ACSM2A ACSM2B

1.38e-0317612IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

1.38e-0317612PF13193
DomainPI3/4_kinase_cat_dom

PIK3CG PI4KA

1.55e-0318612IPR000403
DomainATP_grasp_subdomain_1

CPS1 PCCA

1.55e-0318612IPR013815
DomainPI3_PI4_kinase

PIK3CG PI4KA

1.55e-0318612PF00454
DomainPI3_4_KINASE_3

PIK3CG PI4KA

1.55e-0318612PS50290
DomainPI3_4_KINASE_1

PIK3CG PI4KA

1.55e-0318612PS00915
DomainPI3_4_KINASE_2

PIK3CG PI4KA

1.55e-0318612PS00916
Domain-

CPS1 PCCA

1.55e-03186123.30.470.20
DomainKinase-like_dom

MAK NUAK1 PIK3CG PI4KA PKN2 ERN2 MAP3K3

1.87e-03542617IPR011009
DomainRicin_B_lectin

GALNT10 GALNT4

3.00e-0325612PF00652
DomainAMP-binding_CS

ACSM2A ACSM2B

3.24e-0326612IPR020845
DomainRICIN

GALNT10 GALNT4

3.76e-0328612SM00458
DomainAMP_BINDING

ACSM2A ACSM2B

3.76e-0328612PS00455
DomainRICIN_B_LECTIN

GALNT10 GALNT4

3.76e-0328612PS50231
DomainAMP-binding

ACSM2A ACSM2B

4.30e-0330612PF00501
DomainRicin_B_lectin

GALNT10 GALNT4

4.30e-0330612IPR000772
DomainAMP-dep_Synth/Lig

ACSM2A ACSM2B

4.30e-0330612IPR000873
DomainGlycos_transf_2

GALNT10 GALNT4

4.30e-0330612PF00535
DomainGlyco_trans_2-like

GALNT10 GALNT4

4.30e-0330612IPR001173
DomainATP_grasp_subdomain_2

CPS1 PCCA

4.59e-0331612IPR013816
DomainSer/Thr_kinase_AS

MAK NUAK1 PKN2 ERN2 MAP3K3

6.15e-03357615IPR008271
DomainS_TKc

MAK NUAK1 PKN2 ERN2 MAP3K3

6.29e-03359615SM00220
DomainPROTEIN_KINASE_ST

MAK NUAK1 PKN2 ERN2 MAP3K3

6.51e-03362615PS00108
PathwayREACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE

ACSM2A ACSM2B

1.62e-046472MM14693
PathwayREACTOME_AMINO_ACID_CONJUGATION

ACSM2A ACSM2B

2.26e-047472MM14598
PathwayBIOCARTA_PLC_PATHWAY

PIK3CG PIK3R1

3.86e-049472M22029
PathwayBIOCARTA_PLC_PATHWAY

PIK3CG PIK3R1

3.86e-049472MM1551
PathwayREACTOME_AMINO_ACID_CONJUGATION

ACSM2A ACSM2B

3.86e-049472M26968
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

PARP2 POLQ

7.03e-0412472M27569
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

PARP2 POLQ

7.03e-0412472MM15282
PathwayREACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOINOSITIDE_3_KINASE_PI3K

PIK3CG PIK3R1

7.03e-0412472M27905
PathwayREACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOINOSITIDE_3_KINASE_PI3K

PIK3CG PIK3R1

7.03e-0412472MM15623
PathwayBIOCARTA_ACH_PATHWAY

PIK3CG PIK3R1

9.65e-0414472M16884
PathwayBIOCARTA_ERK5_PATHWAY

PIK3CG PIK3R1

9.65e-0414472MM1481
PathwayWP_CANCER_IMMUNOTHERAPY_BY_CTLA4_BLOCKADE

CD86 PIK3R1

9.65e-0414472M39840
PathwayBIOCARTA_ACH_PATHWAY

PIK3CG PIK3R1

9.65e-0414472MM1485
PathwayBIOCARTA_ERK5_PATHWAY

PIK3CG PIK3R1

9.65e-0414472M16811
PathwayBIOCARTA_LONGEVITY_PATHWAY

PIK3CG PIK3R1

1.11e-0315472M13158
PathwayBIOCARTA_BCELLSURVIVAL_PATHWAY

PIK3CG PIK3R1

1.11e-0315472M4835
PathwayBIOCARTA_ARF_PATHWAY

PIK3CG PIK3R1

1.27e-0316472MM1524
PathwayBIOCARTA_CTLA4_PATHWAY

CD86 PIK3R1

1.27e-0316472MM1512
PathwayBIOCARTA_IL7_PATHWAY

PIK3CG PIK3R1

1.27e-0316472M1296
PathwayBIOCARTA_IL7_PATHWAY

PIK3CG PIK3R1

1.27e-0316472MM1420
PathwayBIOCARTA_GCR_PATHWAY

PIK3CG PIK3R1

1.43e-0317472M10066
PathwayBIOCARTA_BCELLSURVIVAL_PATHWAY

PIK3CG PIK3R1

1.43e-0317472MM1353
PathwayREACTOME_SIGNALING_BY_ERYTHROPOIETIN

PIK3CG PIK3R1

1.43e-0317472MM15584
PathwayBIOCARTA_HCMV_PATHWAY

PIK3CG PIK3R1

1.43e-0317472M8353
PathwayBIOCARTA_GCR_PATHWAY

PIK3CG PIK3R1

1.43e-0317472MM1372
PathwayBIOCARTA_HCMV_PATHWAY

PIK3CG PIK3R1

1.43e-0317472MM1408
PathwayBIOCARTA_ARF_PATHWAY

PIK3CG PIK3R1

1.43e-0317472M11358
PathwayREACTOME_SIGNALING_BY_ALK

PTPRZ1 PIK3R1

1.43e-0317472MM14790
PathwayBIOCARTA_LONGEVITY_PATHWAY

PIK3CG PIK3R1

1.79e-0319472MM1513
PathwayBIOCARTA_PAR1_PATHWAY

PIK3CG PIK3R1

1.79e-0319472MM1514
PathwayBIOCARTA_PAR1_PATHWAY

PIK3CG PIK3R1

1.79e-0319472M3494
PathwayBIOCARTA_ECM_PATHWAY

PIK3CG PIK3R1

1.79e-0319472M6355
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

FAT1 PIK3CG PIK3R1

1.91e-0374473M39857
PathwayKEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY

PIK3CG PIK3R1 RASGRP3

1.98e-0375473M5436
PathwayBIOCARTA_EDG1_PATHWAY

PIK3CG PIK3R1

1.99e-0320472MM1456
PathwayBIOCARTA_NGF_PATHWAY

PIK3CG PIK3R1

1.99e-0320472M7860
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

PIK3CG PIK3R1 PI4KA

2.06e-0376473M9052
PathwayREACTOME_PI_METABOLISM

PIK3CG PIK3R1 PI4KA

2.14e-0377473MM14590
PathwayBIOCARTA_RAC1_PATHWAY

PIK3CG PIK3R1

2.19e-0321472M8601
PathwayBIOCARTA_IGF1_PATHWAY

PIK3CG PIK3R1

2.19e-0321472M2623
PathwayBIOCARTA_ECM_PATHWAY

PIK3CG PIK3R1

2.19e-0321472MM1390
PathwayBIOCARTA_RAC1_PATHWAY

PIK3CG PIK3R1

2.19e-0321472MM1463
PathwayBIOCARTA_RAS_PATHWAY

PIK3CG PIK3R1

2.19e-0321472MM1464
PathwayBIOCARTA_INSULIN_PATHWAY

PIK3CG PIK3R1

2.19e-0321472M765
PathwayBIOCARTA_EDG1_PATHWAY

PIK3CG PIK3R1

2.41e-0322472M10579
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

CD86 PIK3R1

2.41e-0322472M13897
PathwayBIOCARTA_IGF1_PATHWAY

PIK3CG PIK3R1

2.41e-0322472MM1409
PathwayBIOCARTA_NGF_PATHWAY

PIK3CG PIK3R1

2.41e-0322472MM1440
PathwayBIOCARTA_AKT_PATHWAY

PIK3CG PIK3R1

2.41e-0322472M15258
PathwayBIOCARTA_RAS_PATHWAY

PIK3CG PIK3R1

2.41e-0322472M17294
PathwayBIOCARTA_CTLA4_PATHWAY

CD86 PIK3R1

2.41e-0322472M1467
PathwayBIOCARTA_HER2_PATHWAY

PIK3CG PIK3R1

2.63e-0323472MM1480
PathwayBIOCARTA_GLEEVEC_PATHWAY

PIK3CG PIK3R1

2.63e-0323472MM1424
PathwayBIOCARTA_HER2_PATHWAY

PIK3CG PIK3R1

2.63e-0323472M18719
PathwayBIOCARTA_GLEEVEC_PATHWAY

PIK3CG PIK3R1

2.63e-0323472M7897
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

CD86 PIK3R1

2.63e-0323472MM14993
PathwayREACTOME_PI_METABOLISM

PIK3CG PIK3R1 PI4KA

2.74e-0384473M676
PathwayBIOCARTA_CTCF_PATHWAY

PIK3CG PIK3R1

2.87e-0324472M11420
PathwayBIOCARTA_CTCF_PATHWAY

PIK3CG PIK3R1

2.87e-0324472MM1373
PathwayBIOCARTA_BAD_PATHWAY

PIK3CG PIK3R1

2.87e-0324472MM1467
PathwayBIOCARTA_INSULIN_PATHWAY

PIK3CG PIK3R1

2.87e-0324472MM1425
PathwayBIOCARTA_TPO_PATHWAY

PIK3CG PIK3R1

2.87e-0324472M11520
PathwayBIOCARTA_TFF_PATHWAY

PIK3CG PIK3R1

2.87e-0324472M15926
PathwayBIOCARTA_TPO_PATHWAY

PIK3CG PIK3R1

3.11e-0325472MM1519
PathwayBIOCARTA_BAD_PATHWAY

PIK3CG PIK3R1

3.11e-0325472M85
PathwayBIOCARTA_HDAC_PATHWAY

PIK3CG PIK3R1

3.11e-0325472M1547
PathwayREACTOME_SIGNALING_BY_ERYTHROPOIETIN

PIK3CG PIK3R1

3.11e-0325472M27865
PathwayBIOCARTA_HDAC_PATHWAY

PIK3CG PIK3R1

3.36e-0326472MM1371
PathwayWP_EGFR1_SIGNALING_PATHWAY

PIK3CG PIK3R1 PKN2 MAP3K3

3.49e-03188474MM15828
PathwayBIOCARTA_VEGF_PATHWAY

PIK3CG PIK3R1

3.62e-0327472M12975
PathwayBIOCARTA_GH_PATHWAY

PIK3CG PIK3R1

3.62e-0327472M9043
Pubmed

Antidepressant-like effect of valproic acid-Possible involvement of PI3K/Akt/mTOR pathway.

PIK3CG PIK3R1

3.23e-06263228408298
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

3.23e-06263216521160
Pubmed

Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells.

PIK3CG PIK3R1

3.23e-06263223143475
Pubmed

PI3Kγ inhibition alleviates symptoms and increases axon number in experimental autoimmune encephalomyelitis mice.

PIK3CG PIK3R1

3.23e-06263224012746
Pubmed

Haploinsufficiency of autism spectrum disorder candidate gene NUAK1 impairs cortical development and behavior in mice.

NUAK1 NEUROD6

3.23e-06263230327473
Pubmed

The p85 and p110 subunits of phosphatidylinositol 3-kinase-alpha are substrates, in vitro, for a constitutively associated protein tyrosine kinase in platelets.

PIK3CG PIK3R1

3.23e-0626329446654
Pubmed

Phosphoinositide 3-kinase is not overexpressed in melanocytic lesions.

PIK3CG PIK3R1

3.23e-06263217302605
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

3.23e-06263219634011
Pubmed

Important roles of PI3Kgamma in osteoclastogenesis and bone homeostasis.

PIK3CG PIK3R1

3.23e-06263220616072
Pubmed

Association between phosphatidylinositol 3-kinase regulatory subunit p85alpha Met326Ile genetic polymorphism and colon cancer risk.

PIK3CG PIK3R1

3.23e-06263218245521
Pubmed

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

PIK3CG PIK3R1

3.23e-0626328313897
Pubmed

Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy.

PIK3CG PIK3R1

3.23e-06263215741161
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

3.23e-06263229948332
Pubmed

O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.

CPS1 PCCA

3.23e-06263236064721
Pubmed

CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase C gamma 2/protein kinase C alpha beta signaling pathways.

CD86 PIK3R1

9.68e-06363216709832
Pubmed

Interleukin-6 activates phosphatidylinositol-3 kinase, which inhibits apoptosis in human prostate cancer cell lines.

PIK3CG PIK3R1

9.68e-06363210579793
Pubmed

Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling.

PIK3CG PIK3R1

9.68e-06363216699071
Pubmed

Frameshift mutations of OGDH, PPAT and PCCA genes in gastric and colorectal cancers.

PPAT PCCA

9.68e-06363227468871
Pubmed

Rapid, nongenomic actions of retinoic acid on phosphatidylinositol-3-kinase signaling pathway mediated by the retinoic acid receptor.

PIK3CG PIK3R1

9.68e-06363217595318
Pubmed

Galpha q inhibits cardiac L-type Ca2+ channels through phosphatidylinositol 3-kinase.

PIK3CG PIK3R1

9.68e-06363216186103
Pubmed

Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.

PTPRZ1 DTNA NEUROD6

1.27e-052563319373938
Pubmed

Association of T cell antigen CD7 with type II phosphatidylinositol-4 kinase, a key component in pathways of inositol phosphate turnover.

PIK3R1 PI4KA

1.93e-05463212594831
Pubmed

Mapping and developmental expression analysis of the WD-repeat gene Preb.

CRMP1 FGL2

1.93e-05463210704286
Pubmed

Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit.

PIK3CG PIK3R1

1.93e-05463215932879
Pubmed

CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.

PIK3CG PIK3R1

1.93e-05463218006698
Pubmed

Phosphoinositide 3-kinaseγ controls the intracellular localization of CpG to limit DNA-PKcs-dependent IL-10 production in macrophages.

PIK3CG PIK3R1

1.93e-05463222053215
Pubmed

Heat shock cognate protein 70 is essential for Akt signaling in endothelial function.

PIK3CG PIK3R1

1.93e-05463220018937
Pubmed

Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.

TNFSF11 PIK3R1

1.93e-05463217053831
Pubmed

Vascular endothelial growth factor receptor 1 contributes to Escherichia coli K1 invasion of human brain microvascular endothelial cells through the phosphatidylinositol 3-kinase/Akt signaling pathway.

PIK3CG PIK3R1

1.93e-05463220805333
Pubmed

Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.

ACSM2A ACSM2B

1.93e-05463232830538
Pubmed

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.

SLC30A8 PKN2

1.93e-05463218443202
Pubmed

The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice.

PTPRZ1 PIK3R1

1.93e-05463230667096
Pubmed

RANKL-induced down-regulation of CX3CR1 via PI3K/Akt signaling pathway suppresses Fractalkine/CX3CL1-induced cellular responses in RAW264.7 cells.

TNFSF11 PIK3R1

3.22e-05563217963723
Pubmed

IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation.

PIK3CG PIK3R1

3.22e-05563219376889
Pubmed

DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis.

PIK3CG PIK3R1

3.22e-05563219903888
Pubmed

The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.

PIK3CG PIK3R1

3.22e-05563220200404
Pubmed

FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival.

PIK3CG PIK3R1

3.22e-05563218374639
Pubmed

Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.

PIK3CG PIK3R1

3.22e-05563212774123
Pubmed

CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28.

PIK3CG CD86

3.22e-0556329915850
Pubmed

Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.

PIK3R1 NEUROD6

3.22e-05563225157163
Pubmed

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.

PIK3R1 PI4KA

3.22e-0556328246987
Pubmed

Large-scale investigation of genomic markers for severe periodontitis.

PIK3R1 FGL2

3.22e-05563215490304
Pubmed

The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions.

NUAK1 NEUROD6

3.22e-05563238514619
Pubmed

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.

PIK3CG PIK3R1

4.82e-05663219574958
Pubmed

C-mip interacts with the p85 subunit of PI3 kinase and exerts a dual effect on ERK signaling via the recruitment of Dip1 and DAP kinase.

PIK3CG PIK3R1

4.82e-05663220018188
Pubmed

A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1α and HIF2α stability and tumor growth, angiogenesis, and metastasis.

PIK3CG PIK3R1

4.82e-05663225103499
Pubmed

Deficient tyrosine phosphorylation of c-Cbl and associated proteins in phorbol ester-resistant EL4 mouse thymoma cells.

PIK3CG PIK3R1

4.82e-0566329115297
Pubmed

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.

PIK3CG PIK3R1

6.74e-05763220167705
Pubmed

Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture.

NUAK1 NEUROD6

6.74e-05763223791179
Pubmed

Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells.

PIK3R1 PI4KA

6.74e-05763217242350
Pubmed

Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes.

SLC22A23 ARMH4

8.98e-05863218246200
Pubmed

Regulation of membrane traffic by phosphoinositide 3-kinases.

PIK3CG PIK3R1

8.98e-05863216467569
Pubmed

Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development.

GALNT10 GALNT4

8.98e-05863211159923
Pubmed

Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases.

PIK3CG PIK3R1

8.98e-05863218467332
Pubmed

Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study).

SLC30A8 PKN2

8.98e-05863218437351
Pubmed

Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.

CPS1 ACSM2A PCCA ACSM2B

9.93e-0513263422496890
Pubmed

Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore.

SLC30A8 PKN2

1.15e-04963219892838
Pubmed

The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains.

PIK3CG PIK3R1

1.15e-04963210571082
Pubmed

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations.

PIK3CG PIK3R1

1.15e-04963215192701
Pubmed

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.

PIK3CG PIK3R1

1.15e-04963210871282
Pubmed

Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat.

PIK3CG PIK3R1

1.15e-04963221765914
Pubmed

Role and regulation of PDGFRα signaling in liver development and regeneration.

PIK3CG PIK3R1

1.15e-04963223529017
Pubmed

P110delta, a novel phosphoinositide 3-kinase in leukocytes.

PIK3CG PIK3R1

1.44e-04106329113989
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3CG PIK3R1

1.44e-04106328636073
Pubmed

Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and corticotropin-releasing hormone deficiency.

CRMP1 FGL2

1.44e-041063210614646
Pubmed

LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway.

PIK3R1 CRMP1

1.44e-041063237037996
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3CG PIK3R1

1.44e-04106328798481
Pubmed

Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.

PIK3CG PIK3R1

1.44e-041063219889638
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3CG PIK3R1

1.44e-04106329247029
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PI4KA SIPA1L1 PKN2 CTNND2 CRMP1

1.59e-0428163528706196
Pubmed

Slc20a2 deficiency results in fetal growth restriction and placental calcification associated with thickened basement membranes and novel CD13 and lamininα1 expressing cells.

CD86 SLC20A2

1.76e-041163226952749
Pubmed

HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

PIK3CG PIK3R1

1.76e-041163216081599
Pubmed

HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.

PIK3CG PIK3R1

1.76e-04116329708406
Pubmed

HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.

PIK3CG PIK3R1

1.76e-041163210985305
Pubmed

Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.

PIK3CG PIK3R1

1.76e-041163212584329
Pubmed

Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.

PIK3CG PIK3R1

1.76e-04116329808187
Pubmed

HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway.

PIK3CG PIK3R1

1.76e-041163225104021
Pubmed

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons.

PIK3CG PIK3R1

1.76e-04116329852579
Pubmed

Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.

PIK3CG PIK3R1

2.11e-041263220665729
Pubmed

Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.

PIK3CG PIK3R1

2.11e-041263214602571
Pubmed

Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.

PIK3CG PIK3R1

2.11e-041263216514418
Pubmed

Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry.

SLC30A8 PKN2

2.11e-041263219380854
Pubmed

A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone.

TNFSF11 CD86

2.11e-041263230684382
Pubmed

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

PIK3CG PIK3R1

2.11e-041263210208934
Pubmed

Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.

PIK3CG PIK3R1

2.11e-041263212077252
Pubmed

Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.

PIK3CG PIK3R1

2.11e-04126329341793
Pubmed

Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.

PIK3CG PIK3R1

2.11e-041263212551992
Pubmed

HIV-1 Nef in macrophage-mediated disease pathogenesis.

PIK3CG PIK3R1

2.49e-041363223215766
Pubmed

Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.

PIK3CG PIK3R1

2.49e-04136329394803
Pubmed

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.

NUAK1 PIK3R1

2.90e-041463223419831
Pubmed

Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.

PIK3CG PIK3R1

2.90e-041463217157319
Pubmed

The genes encoding glucokinase regulatory protein and ketohexokinase co-localize to mouse chromosome 5.

CRMP1 FGL2

2.90e-04146329271679
Pubmed

HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.

PIK3CG PIK3R1

3.34e-041563218854243
Pubmed

Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action.

PIK3CG PIK3R1

3.34e-041563220702582
Pubmed

ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.

ADAMTS3 PTPRZ1

3.34e-041563238871984
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

PIK3CG PIK3R1

3.81e-041663216524887
Pubmed

HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.

PIK3CG PIK3R1

3.81e-041663211289809
Pubmed

Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.

PIK3CG PIK3R1

3.81e-041663220019835
Pubmed

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.

PIK3CG PIK3R1

3.81e-041663221029719
Pubmed

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders.

PIK3CG PIK3R1

3.81e-041663220818790
Cytoband16q22.1

PDPR PLEKHG4 SLC7A6

4.79e-0411063316q22.1
Cytoband16p12.3

ACSM2A ACSM2B

1.01e-033463216p12.3
CytobandEnsembl 112 genes in cytogenetic band chr16p12

ERN2 ACSM2A ACSM2B

1.74e-03172633chr16p12
CytobandEnsembl 112 genes in cytogenetic band chr16q22

PDPR PLEKHG4 SLC7A6

2.08e-03183633chr16q22
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT10 GALNT4

8.84e-0420402433
GeneFamilyAcyl-CoA synthetase family

ACSM2A ACSM2B

1.50e-032640240
CoexpressionLU_IL4_SIGNALING

CD86 RASGRP3 PKN2 KMO FGL2

2.71e-0691635M10558
CoexpressionWIKMAN_ASBESTOS_LUNG_CANCER_DN

CD86 MS4A6A FGL2

5.13e-0530633M9729
CoexpressionMONNIER_POSTRADIATION_TUMOR_ESCAPE_UP

PDPR RBM27 PIK3R1 SLC22A23 PPAT SLC7A6 KHDC4

5.49e-05408637M11891
CoexpressionMONNIER_POSTRADIATION_TUMOR_ESCAPE_UP

PDPR RBM27 PIK3R1 SLC22A23 PPAT SLC7A6 KHDC4

6.11e-05415637MM1028
CoexpressionSTK33_UP

RNF121 NUAK1 RASGRP3 KMO GALNT4 FGL2

6.46e-05286636M2858
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_6HR_DN

GALNT10 NUAK1 SSBP2 CTNND2

6.92e-0591634M2154
CoexpressionAtlasMyeloid Cells, DC.103+11b-.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD103+ CD11b-, Small Intestine, avg-5

CD86 RASGRP3 KMO FGL2

5.84e-0572624GSM854246_100
CoexpressionAtlasMyeloid Cells, DC.103+11b-.Lv, CD45+ CD11c+ MHC-II+ CD11b low CD103+, Liver, avg-2

CD86 RASGRP3 KMO FGL2

9.26e-0581624GSM538234_100
CoexpressionAtlasMyeloid Cells, DC.103+11b-.Lu, CD11chi CD11b low CD103+ MHCII+ SiglecF-, Lung, avg-3

CD86 RASGRP3 KMO FGL2

9.72e-0582624GSM538231_100
CoexpressionAtlasMyeloid Cells, DC.103+11b-.Lu, MHCII+ CD11c+ CD103+ CD11b, Lung, avg-2

CD86 RASGRP3 KMO FGL2

1.02e-0483624GSM854241_100
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT1 CYP2J2 PTPRZ1 DHCR24 ERN2 GK5

3.50e-0719663670384c1da9baed843f414cfd1403ddd586a2db07
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD86 CTNND2 SLC7A6 POLQ KMO

3.18e-061606358a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDPR VPS8 CCDC168 POLQ FGL2

4.03e-06168635a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD86 MS4A6A KMO MAP3K3 FGL2

4.27e-0617063546a81d505de845cc59f80594fce338f7fdb9250f
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD86 MS4A6A KMO MAP3K3 FGL2

4.27e-061706351a9a0487c35cf3fd5806d1f0f0e91ef0e0b9cd0a
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD86 MS4A6A KMO MAP3K3 FGL2

4.27e-06170635830646815410c47e9bca8c9bae75dfc45c9c9b33
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3CG CD86 SLC7A6 MS4A6A FGL2

6.97e-0618863572a1ee136d77c77e44793a512f60b5f7815a073a
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3CG CD86 SLC7A6 MS4A6A FGL2

6.97e-06188635ecbba19eebba21b986caa99de78ea4245fde3600
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

7.16e-06189635440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

7.34e-06190635e0b363f772817cfc6ab425430805c1cddcba23f0
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

CD86 SIPA1L1 SSBP2 MS4A6A FGL2

7.53e-061916352af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellIPF-Myeloid-cDC2|World / Disease state, Lineage and Cell class

CD86 SIPA1L1 SSBP2 MS4A6A FGL2

7.53e-061916359fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

7.53e-0619163509dfad8e1fcaaf94775134796b99e4e3fbb9bf40
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

7.53e-0619163503e1ac489e918c7affc1cdc09fb3eb255bcf80e5
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

CD86 SIPA1L1 SSBP2 MS4A6A FGL2

7.53e-061916354e4887175200a57e1b041f2f131e3df774df3509
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

CD86 SIPA1L1 SSBP2 MS4A6A FGL2

7.72e-06192635984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GALNT10 ADAMTS3 RBM27 SLC20A2 DHCR24

7.92e-061936350ef076417ffe2dd1cbc2c3d1e35c7f8522af143b
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

8.12e-06194635ef30baa19b7aa97b61dea916fc2e0f5cf49848d6
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYP2J2 PTPRZ1 DHCR24 ATP13A5 ERN2

8.12e-061946352172d951896265243d14996eacce5aab5e14e26e
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

8.12e-06194635846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

CD86 SIPA1L1 SSBP2 MS4A6A FGL2

8.12e-06194635accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

CD86 SIPA1L1 VPS8 MS4A6A KMO

8.54e-061966354929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

PIK3CG CD86 PI4KA SLC7A6 KHDC4

8.54e-0619663509d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

NUAK1 SIPA1L1 SSBP2 CTNND2 NEUROD6

8.75e-0619763579b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

NUAK1 SIPA1L1 SSBP2 CTNND2 NEUROD6

8.75e-06197635d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DTNA PIK3CG CD86 MS4A6A FGL2

8.75e-06197635363ae03310f63a586ba3cea2a59f35d5a335a54e
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNFSF11 CD86 RASGRP3 MS4A6A KMO

8.97e-061986356a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellPCW_13-14-Hematologic_Myeloid|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A KMO FGL2

8.97e-06198635d42fce8e547dc97f3cf144ab65483a1b11ace267
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Macroglial-Astrocyte|6m / Sample Type, Dataset, Time_group, and Cell type.

FEZ2 PTPRZ1 DTNA NMB CTNND2

9.41e-062006356ff22adb3007c3c9ef64a05c9dbc1d440bdaee1b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Macroglial|6m / Sample Type, Dataset, Time_group, and Cell type.

FEZ2 PTPRZ1 DTNA NMB CTNND2

9.41e-0620063542dc8ed66a021097e703eef2d756607396ca2f56
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA17 CD86 KMO FGL2

5.46e-05146634b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAMTS3 PTPRZ1 DTNA NMB

7.06e-05156634bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD86 POLQ KMO ARMH4

7.06e-05156634af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRZ1 DTNA ATP13A5 CPS1

7.79e-05160634c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRZ1 DTNA ATP13A5 CPS1

7.79e-0516063425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG CD86 CTNND2 FGL2

9.20e-05167634991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG CD86 CTNND2 FGL2

9.20e-05167634f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

RNF121 RBM27 MS4A6A FGL2

9.20e-05167634820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG CD86 CTNND2 FGL2

9.20e-05167634934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF11 CD86 MS4A6A KMO

9.41e-0516863461a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD86 CTNND2 KMO FGL2

9.41e-0516863499148986aa5628f67d85258c171b254be77a071c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNFSF11 CD86 MS4A6A KMO

9.41e-0516863426fce414439ccd204e3acb41f2b4f75072df5a26
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3CG CD86 MS4A6A FGL2

9.41e-051686342dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

NMB POLQ CRMP1 FGL2

9.63e-05169634625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DTNA CD86 CTNND2 MS4A6A

9.85e-051706344232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Lung-LUNG-30m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD86 CTNND2 KMO FGL2

9.85e-05170634ece7c20e89c190a7ec68032b6c2efeb458c43f9a
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3CG CD86 MS4A6A FGL2

9.85e-051706343cbeea6bfa500928c413b1c6129f6dedc769cd1e
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CD86 CCDC168 MS4A6A FGL2

9.85e-05170634403b6b749d70d845838dcda7daf99971b50792a2
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DTNA CD86 MS4A6A FGL2

9.85e-051706347bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DTNA CD86 MS4A6A FGL2

9.85e-05170634a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD86 RASGRP3 MS4A6A FGL2

1.01e-041716345e93c76ee60f9d0590ebb140812653a5e1369417
ToppCellILEUM-non-inflamed-(3)_Inf._Macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CD86 MS4A6A KMO FGL2

1.05e-04173634a8db746992a915a8431ac5c155612e89c4af3cad
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2J2 PTPRZ1 STOX1 ERN2

1.05e-04173634464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

FEZ2 CD86 RASGRP3 MS4A6A

1.08e-0417463475b3a852140fb726025c3c987143d67944afde2d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUAK1 DTNA DHCR24 CRMP1

1.08e-0417463446bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD86 MS4A6A KMO FGL2

1.10e-04175634cd42020fe57afeaadfbd3ef6d7375e66d71e9669
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CD86 MS4A6A KMO FGL2

1.13e-0417663498176bf3c961d5262593e2d5d002836adb010e13
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPATA17 PTPRZ1 PIK3CG CCDC168

1.15e-04177634f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD86 MS4A6A KMO FGL2

1.15e-04177634cdad5a2f672a7f07c05669bfcaf1ec74defd3de7
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFSF11 ADAMTS3 DTNA STARD9

1.15e-04177634e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellASK428-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

NUAK1 PTPRZ1 CD86 ATP13A5

1.15e-0417763466074a288501c136b4e83b883db5f0d8269ee326
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD86 MS4A6A KMO FGL2

1.15e-04177634991ae76bb615392d84aeb89886148fa42c1c649c
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

NUAK1 PTPRZ1 SSBP2 ACSM2B

1.18e-04178634441d1dba720141891b11f404744c59834d80e6c5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CD86 ATP13A5 POLQ MS4A6A

1.18e-0417863424e8c62060455159235985f456af0c5023a7f3f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CD86 ATP13A5 POLQ MS4A6A

1.18e-041786344f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFSF11 CD86 PI4KA ERN2

1.20e-041796344f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF11 CD86 PI4KA ERN2

1.20e-04179634d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD86 MS4A6A KMO FGL2

1.23e-0418063497241f62ee133dcb0d4855ffda5dd1349de9f7b2
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD86 MS4A6A KMO FGL2

1.23e-0418063441896546cd1cc458e08c0d4e19aa4860e5d4fcd6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DTNA PIK3CG CD86 FGL2

1.25e-041816346771f2c72073c59aab905945a619907b7fd0fd77
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Kidney/Urine in Lupus Nephritis

RASGRP3 SSBP2 IGLV4-69 KMO

1.28e-0418263463c3b63315276b66667d49fab09661ac320e7a36
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD86 MS4A6A KMO FGL2

1.28e-04182634d5d6bc16458bc665e7ad6669040d79f73f640044
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

CYP2J2 DTNA SLC20A2 CTNND2

1.28e-04182634287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD86 MS4A6A KMO FGL2

1.28e-041826340b59ead4bb4486c7ec2ee90b94ee3a09905612c5
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2J2 PTPRZ1 STOX1 ERN2

1.28e-041826343f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC30A8 ACSM2A KMO ACSM2B

1.28e-0418263457bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A FGL2

1.31e-04183634aed12b743334f3813db0c70d4fe7df90e0673f54
ToppCellDendritic_Cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CD86 SIPA1L1 MS4A6A FGL2

1.31e-04183634dd09e39e8ca282ff0f470e0652d519e190badd0b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUAK1 DTNA DHCR24 CRMP1

1.31e-0418363483592c332b1e82673f993d37c7f480befdc3dcda
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A FGL2

1.31e-0418363424679153b654c148dbd572e9013c0a6e58718ada
ToppCellwk_08-11-Hematologic-Myeloid-DC3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A FGL2

1.34e-041846347d9294e5a55964903feda135e5bea0338824ed83
ToppCellCOVID-19_Convalescent-Myeloid-cDC|COVID-19_Convalescent / Disease group, lineage and cell class

DTNA CD86 MS4A6A FGL2

1.34e-04184634ad6e910eaebe841a68a5f2f329d43dafc5db158a
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DTNA CD86 MS4A6A FGL2

1.34e-041846349d678b24532b7763f2e73f7ccb496259977c5204
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DTNA CD86 MS4A6A FGL2

1.34e-04184634383374ad17bd322b8d703a22e475d34ca7b2e6b6
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A23 DHCR24 KMO ACSM2B

1.34e-041846343d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCellPBMC-Convalescent-Myeloid-cDC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

DTNA CD86 MS4A6A FGL2

1.34e-041846345535b85b3ad3d0c0392d5884fdc2939c7e1b1c3e
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A23 DHCR24 KMO ACSM2B

1.34e-0418463445577ff91c3b2b303acd97239dde2463ea7a429c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DTNA PIK3CG CD86 FGL2

1.36e-041856340a87d2ee8fffc812224c05a26c729733a5e64d2c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DTNA PIK3CG CD86 FGL2

1.36e-04185634e63fde030be822ebf32143a41f8cc684cb720f5b
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A FGL2

1.39e-041866346575ec6a626cdea169ffd185d47828dfaa29475d
ToppCell10x5'-Liver-Myeloid_Dendritic-DC2|Liver / Manually curated celltypes from each tissue

DTNA CD86 MS4A6A FGL2

1.39e-0418663492ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A FGL2

1.39e-04186634fc6e591089c87a66653c8e552be9c0fe0c82ecd5
ToppCellDendritic_Cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

CD86 POLQ MS4A6A FGL2

1.39e-041866341d52912bd17e232cf39b2423a4d93585c164ba34
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 DTNA ACSM2A ACSM2B

1.39e-04186634f28d72b47624b69a580b4429e2be560a26898591
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

CD86 RASGRP3 SIPA1L1 KMO

1.42e-041876344e64be635f445276e71f2937f33f041c3a4204ab
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

FAT1 DTNA ACSM2A ACSM2B

1.42e-04187634d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DTNA CD86 MS4A6A FGL2

1.42e-0418763439b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell10x5'-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

DTNA CD86 MS4A6A FGL2

1.42e-04187634ab9c9930341527122f26fe5544c5c4818d1fd1b5
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PIK3CG CD86 SIPA1L1 MS4A6A

1.45e-041886343be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PIK3CG CD86 MS4A6A FGL2

1.45e-041886348fc15c8b78fdd1a578e34325011bc5a87a8aab31
DiseaseX-21319 measurement

ACSM2A ACSM2B

4.20e-062612EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

1.26e-053612EFO_0021242
Diseaseotosclerosis

MAK TNFSF11 SIPA1L1 SLC7A6

2.44e-0581614EFO_0004213
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

4.19e-055612EFO_0800378
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

6.27e-056612EFO_0800106
Diseaseglutaroyl carnitine measurement

CPS1 SLC7A6

3.23e-0413612EFO_0021005
Diseasebody surface area

SPATA17 UBN1 ADAMTS3 FEZ2 PIK3R1 CPS1 MAP3K3

3.55e-04643617EFO_0022196
Diseasediffuse idiopathic skeletal hyperostosis

PIK3R1 SLC30A8

4.34e-0415612EFO_0007236
Diseasecortical thickness

TNFSF11 UBN1 NUAK1 ADAMTS3 PIK3R1 PI4KA STOX1 PCCA CRMP1

4.45e-041113619EFO_0004840
Diseasecarnitine measurement

PIK3CG CPS1 PCCA

5.31e-0476613EFO_0010469
Diseaseglutarylcarnitine (C5-DC) measurement

CPS1 SLC7A6

5.60e-0417612EFO_0800030
DiseaseDepression, Bipolar

STARD9 SSBP2 KMO

5.94e-0479613C0005587
Diseasealanine measurement

SLC30A8 CPS1 SLC7A6

7.61e-0486613EFO_0009765
Diseaseserum homoarginine measurement

CPS1 CRMP1

7.80e-0420612EFO_0005421
DiseaseLiver Cirrhosis, Experimental

SYNRG FAT1 CD86 SLC22A23 CPS1 KMO FGL2

1.06e-03774617C0023893
Diseaseresponse to quetiapine

GALNT10 SLC22A23

1.53e-0328612GO_0097335
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 PIK3R1

1.53e-0328612DOID:5409 (is_implicated_in)
DiseaseGlioblastoma Multiforme

FAT1 PIK3R1 CTNND2

1.59e-03111613C1621958
Diseasecortical surface area measurement

NUAK1 ADAMTS3 PIK3R1 PKN2 SSBP2 STOX1 CPS1 GK5 PCCA

1.69e-031345619EFO_0010736
Diseasecreatinine measurement, glomerular filtration rate

PIK3R1 CPS1 SLC7A6

1.85e-03117613EFO_0004518, EFO_0005208

Protein segments in the cluster

PeptideGeneStartEntry
GKKEIYMHTGNSSTP

ATP13A5

771

Q4VNC0
YLKEMSKHTGNPTSS

CYP2J2

281

P51589
TSGTSGLPKMAEHSY

ACSM2A

221

Q08AH3
GLGHSPSSYVNTKEM

ARMH4

201

Q86TY3
TCSSIHGYPEPKKMS

CD86

156

P42081
PASEYTMHLGLKSTG

CTNND2

1181

Q9UQB3
YTDHMKGVNSGKSPG

RCL1

226

Q9Y2P8
TPGHPKMIYSSSNLK

RBM27

781

Q9P2N5
YLMKLNSDGSHSKGD

IGLV4-69

66

A0A075B6H9
KGLGKMAPSSAHFVT

PARP2

516

Q9UGN5
NSAAKTYVGHPVKMG

FAT1

46

Q14517
PTSHVYMFKNGSGDS

LYSMD4

21

Q5XG99
KDKTLYHPVSGSCMD

GALNT10

551

Q86SR1
DGSPGKYMSHLASCG

ERN2

191

Q76MJ5
YASTTHLMTGKKVPS

KIAA1109

3846

Q2LD37
SKLYGMKDSATSPPS

KIAA1109

3911

Q2LD37
FSLEKSKSSGPMYLH

FANCM

1386

Q8IYD8
KPLHYTTTMTASVGA

OR5B2

126

Q96R09
GITGTSVAYHLSKMG

PDPR

51

Q8NCN5
YPLSSGMSTISKKSG

PI4KA

1456

P42356
KGMFPGSLAHTTTKV

PTPRZ1

1096

P23471
DVYPDGFKGHMLTKS

PCCA

506

P05165
STKMHGDYTLTLRKG

PIK3R1

361

P27986
TMKKGPSGYGFNLHS

SLC9A3R1

156

O14745
EDGTKMKGYSFGHPS

CPS1

51

P31327
PYHSETPAKKMSLSS

ADAMTS3

1091

O15072
MIHSLSGKKSAIPYG

KMO

86

O15229
SPTMAGGLFAVSKKY

GALNT4

306

Q8N4A0
GLIMGTGIESSSHKY

DHCR24

166

Q15392
IKVDGYMGSTSPSRH

POLQ

166

O75417
GASHSKKPSMGVFKE

MAK

416

P20794
FLPHSYIGNSGMSSK

MS4A6A

221

Q9H2W1
RKPGYIHSGATTSTM

DTNA

676

Q9Y4J8
AHPGGYKSSFKEAKM

FGL2

416

Q14314
ASFMGLKPSTSKYHL

GK5

391

Q6ZS86
SGTLTGSHDYPAKKM

KHDC4

541

Q7Z7F0
YASLLFPKGMKSSDG

CCDC168

3486

Q8NDH2
YGRALSMTHGSVKSP

SLC20A2

311

Q08357
MSYQGKKSIPHITSD

CRMP1

1

Q14194
GKNERSHMPGTYLTT

FEZ2

291

Q9UHY8
PGYETMKNKDTGHSN

MAP3K3

26

Q99759
PSMHLSSKYGPISYK

SPATA17

306

Q96L03
MYGKGKSNSSAVPSD

SSBP2

1

P81877
GPGSSKKYPSLMASN

SYNRG

231

Q9UMZ2
KNKPRSDALMSSYGH

PLEKHG4

826

Q58EX7
YLKPKDTSMGNSSSG

RNF113B

156

Q8IZP6
LIGKYSQHPDSGMSD

SLC22A23

516

A1A5C7
GDSGSHTFPKMKSKF

RASGRP3

626

Q8IV61
PSYTLGMKSLHGEFS

SIPA1L1

1631

O43166
KHSSKYSAGTMDPAL

NUAK1

526

O60285
KMSPSYHQSKGDPTA

VPS8

1336

Q8N3P4
KGMLHFGSSDISPYA

STARD9

3456

Q9P2P6
KSYTMLGRHSDDGPV

KIF25

71

Q9UIL4
MYSNGSSKDRKLHGT

PKN2

161

Q16513
TSGTSGLPKMAEHSY

ACSM2B

221

Q68CK6
FLFVMGTSGKKTSPH

PIK3CG

991

P48736
ESGGMYHCHSGSKPT

SLC30A8

46

Q8IWU4
STDMLTIGHKYPSKE

STOX1

396

Q6ZVD7
SSVPTFKSHKGMGLV

PPAT

56

Q06203
ATGHFMGKKSLEPSS

NMB

51

P08949
STIGFYSESGMPTKH

RNF121

206

Q9H920
YSESGMPTKHLSDSV

RNF121

211

Q9H920
SSHTLMKGGSTKYWS

TNFSF11

251

O14788
SPKGVLVHTASYGMS

SLC7A6

66

Q92536
PYKSSSPKLSGAMSS

UBN1

1026

Q9NPG3
KDGKSLPPSTYMGHF

SNAPC4

131

Q5SXM2
GHGTLDNSKSMKPYN

NEUROD6

221

Q96NK8