Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

BCL9L NCOA3 NCOA6 ARID1B KMT2D NCOA1 MAML2 BCL9 SS18 CREBBP EP300

1.12e-103034811GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

BCL9L NCOA3 NCOA6 ARID1B KMT2D MED8 NCOA1 MAML2 BCL9 SS18 CREBBP CNOT2 EP300

4.74e-105624813GO:0003712
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA3 NCOA6 CREBBP EP300

1.71e-0721484GO:0042975
GeneOntologyMolecularFunctionchromatin binding

FOXO1 ORC1 NCOA3 NCOA6 ARID1B GTF2H1 NCOA1 MLLT6 CHD7 CREBBP EP300

1.07e-067394811GO:0003682
GeneOntologyMolecularFunctionN-acetyltransferase activity

NCOA3 NCOA1 SATL1 CREBBP EP300

1.20e-0678485GO:0008080
GeneOntologyMolecularFunctionmolecular adaptor activity

BCL9L NCOA3 NCOA6 ARID1B KMT2D SGTA MED8 NCOA1 MAML2 BCL9 SS18 CREBBP CNOT2 EP300

2.24e-0613564814GO:0060090
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

BCL9L NCOA3 NCOA6 ARID1B KMT2D MED8 NCOA1 MAML2 BCL9 SS18 CREBBP CNOT2 EP300

2.30e-0611604813GO:0030674
GeneOntologyMolecularFunctionN-acyltransferase activity

NCOA3 NCOA1 SATL1 CREBBP EP300

4.53e-06102485GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

NCOA3 NCOA1 SATL1 CREBBP EP300

4.99e-06104485GO:0016407
GeneOntologyMolecularFunctioncarbamoyl-phosphate synthase (ammonia) activity

CAD CPS1

5.66e-062482GO:0004087
GeneOntologyMolecularFunctioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

CAD CPS1

5.66e-062482GO:0004088
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

5.66e-062482GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

5.66e-062482GO:0044017
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA3 NCOA1 CREBBP EP300

6.76e-0651484GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA3 NCOA1 CREBBP EP300

9.16e-0655484GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NCOA3 NCOA1 CREBBP EP300

1.30e-0560484GO:0034212
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA3 NCOA6 NCOA1 SS18

1.39e-0561484GO:0030374
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

1.69e-053482GO:0043993
GeneOntologyMolecularFunctiontranscription factor binding

FOXO1 NCOA3 NCOA6 GTF2H1 TCF12 NCOA1 CREBBP CNOT2 EP300

6.58e-05753489GO:0008134
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

NCOA3 NCOA6 GTF2H1

7.40e-0534483GO:0046966
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA3 NCOA6 GTF2H1 NCOA1 EP300

8.43e-05187485GO:0016922
GeneOntologyMolecularFunctionbHLH transcription factor binding

TCF12 CREBBP EP300

9.56e-0537483GO:0043425
GeneOntologyMolecularFunctionbeta-catenin binding

FOXO1 BCL9L BCL9 EP300

1.97e-04120484GO:0008013
GeneOntologyMolecularFunctionhistone modifying activity

NCOA3 KMT2D NCOA1 CREBBP EP300

2.18e-04229485GO:0140993
GeneOntologyMolecularFunctioncarbon-nitrogen ligase activity, with glutamine as amido-N-donor

CAD CPS1

2.52e-0410482GO:0016884
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

NCOA3 NCOA1 SATL1 CREBBP EP300

2.60e-04238485GO:0016747
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA3 NCOA6 NCOA1

2.81e-0453483GO:0030331
GeneOntologyMolecularFunctiontranscription coactivator binding

FOXO1 CREBBP EP300

2.97e-0454483GO:0001223
GeneOntologyMolecularFunctiontranscription coregulator binding

FOXO1 CREBBP CNOT2 EP300

3.55e-04140484GO:0001221
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NCOA3 NCOA6 GTF2H1 TCF12 NCOA1 CREBBP EP300

4.50e-04582487GO:0140297
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NCOA3 NCOA6 GTF2H1 NCOA1 CREBBP EP300

4.68e-04417486GO:0061629
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

5.82e-0415482GO:0010484
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOA6 EP300

1.05e-0320482GO:0035259
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

FOXO1 CHD7 EP300

1.05e-0383483GO:1990841
GeneOntologyMolecularFunctionSMAD binding

TCF12 CREBBP EP300

1.16e-0386483GO:0046332
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA6 NCOA1

1.39e-0323482GO:0046965
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

FOXO1 NCOA3 ZNF536 TCF12 DACH2 MED8 NCOA1 CHD7 CREBBP EP300

2.12e-0314594810GO:0000977
GeneOntologyMolecularFunctionnuclear androgen receptor binding

NCOA3 EP300

2.85e-0333482GO:0050681
GeneOntologyMolecularFunctiondisordered domain specific binding

NCOA3 CREBBP

3.96e-0339482GO:0097718
GeneOntologyMolecularFunctionprotein phosphatase 2A binding

FOXO1 CACNA1B

4.58e-0342482GO:0051721
GeneOntologyMolecularFunctionligase activity, forming carbon-nitrogen bonds

CAD CPS1

7.21e-0353482GO:0016879
GeneOntologyMolecularFunctionchromatin DNA binding

FOXO1 CREBBP EP300

7.54e-03167483GO:0031490
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA6 NCOA1

7.75e-0355482GO:0042974
GeneOntologyMolecularFunctionacyltransferase activity

NCOA3 MED8 NCOA1 SATL1 CREBBP EP300

1.03e-02775486GO:0016746
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXO1 NCOA3 KMT2D TCF12 SHOX

1.08e-02560485GO:0001228
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

NCOA3 CREBBP

1.10e-0266482GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

NCOA3 CREBBP

1.10e-0266482GO:0001098
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXO1 NCOA3 KMT2D TCF12 SHOX

1.13e-02566485GO:0001216
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

FOXO1 BCL9L NCOA3 NCOA6 KMT2D TCF12 MED8 NCOA1 SHOX MLLT6 CHD7 MAML2 BCL9 IKBKB EFCAB7 SS18 CREBBP EP300

7.71e-1013904818GO:0045944
GeneOntologyBiologicalProcessresponse to hormone

FOXO1 NCOA3 NCOA6 ZNF536 ARID1B GTF2H1 KMT2D CAD TCF12 NCOA1 CPS1 IKBKB CNOT2 EP300

6.22e-0810424814GO:0009725
GeneOntologyBiologicalProcessstem cell population maintenance

FOXO1 BCL9L NCOA3 BCL9 SS18 CREBBP CNOT2

1.19e-06237487GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

FOXO1 BCL9L NCOA3 BCL9 SS18 CREBBP CNOT2

1.37e-06242487GO:0098727
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NCOA3 ZNF536 GTF2H1 KMT2D NCOA1 CNOT2 EP300

1.45e-06244487GO:0009755
GeneOntologyBiologicalProcessresponse to nitrogen compound

FOXO1 CACNA1B ARID1B CAD TCF12 SGTA NCOA1 RGS9 CPS1 IKBKB MYRF CREBBP EP300

4.45e-0612724813GO:1901698
GeneOntologyBiologicalProcesscellular response to hormone stimulus

FOXO1 NCOA3 ZNF536 ARID1B GTF2H1 KMT2D NCOA1 CPS1 CNOT2 EP300

5.41e-067274810GO:0032870
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOA3 ZNF536 KMT2D NCOA1 CNOT2 EP300

7.14e-06202486GO:0141193
GeneOntologyBiologicalProcessDNA-templated transcription initiation

FOXO1 NCOA6 ARID1B GTF2H1 MED8 EP300

1.53e-05231486GO:0006352
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

IKBKB CREBBP EP300

2.03e-0523483GO:0002223
GeneOntologyBiologicalProcesscellular response to lectin

IKBKB CREBBP EP300

2.03e-0523483GO:1990858
GeneOntologyBiologicalProcessresponse to lectin

IKBKB CREBBP EP300

2.03e-0523483GO:1990840
GeneOntologyBiologicalProcessresponse to organic cyclic compound

CACNA1B NCOA3 KMT2D CAD NCOA1 RGS9 CPS1 MYRF CREBBP CNOT2 EP300

2.21e-0510484811GO:0014070
GeneOntologyBiologicalProcessresponse to steroid hormone

NCOA3 KMT2D CAD NCOA1 CPS1 CNOT2 EP300

2.66e-05381487GO:0048545
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

3.17e-054482GO:0018076
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

NCOA3 ZNF536 KMT2D NCOA1 IKBKB CNOT2 EP300

4.66e-05416487GO:0030522
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

NCOA3 KMT2D CNOT2 EP300

4.99e-0587484GO:0033143
GeneOntologyBiologicalProcesscitrulline biosynthetic process

CAD CPS1

5.28e-055482GO:0019240
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase II promoter

FOXO1 ARID1B GTF2H1 MED8 EP300

7.07e-05186485GO:0006367
GeneOntologyBiologicalProcess'de novo' pyrimidine nucleobase biosynthetic process

CAD CPS1

7.91e-056482GO:0006207
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

NCOA3 KMT2D CNOT2

8.00e-0536483GO:0033146
GeneOntologyBiologicalProcessprotein-DNA complex organization

NCOA3 ARID1B KMT2D MED8 NCOA1 MLLT6 CHD7 SS18 CREBBP EP300

8.27e-059994810GO:0071824
GeneOntologyBiologicalProcesspyrimidine nucleobase biosynthetic process

CAD CPS1

1.47e-048482GO:0019856
GeneOntologyBiologicalProcesscitrulline metabolic process

CAD CPS1

1.89e-049482GO:0000052
GeneOntologyBiologicalProcesschromatin organization

NCOA3 ARID1B KMT2D NCOA1 MLLT6 CHD7 SS18 CREBBP EP300

1.93e-04896489GO:0006325
GeneOntologyBiologicalProcessresponse to peptide hormone

FOXO1 ARID1B CAD TCF12 NCOA1 CPS1 IKBKB

2.10e-04530487GO:0043434
GeneOntologyBiologicalProcessresponse to lipid

FOXO1 CACNA1B NCOA3 KMT2D CAD NCOA1 RGS9 CPS1 CNOT2 EP300

2.21e-0411264810GO:0033993
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

NCOA3 KMT2D CNOT2 EP300

2.81e-04136484GO:0030518
GeneOntologyBiologicalProcesschromatin remodeling

NCOA3 ARID1B KMT2D NCOA1 CHD7 SS18 CREBBP EP300

2.82e-04741488GO:0006338
GeneOntologyBiologicalProcessresponse to ketone

CACNA1B CAD NCOA1 CPS1 EP300

3.03e-04254485GO:1901654
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

NCOA3 KMT2D CNOT2

3.17e-0457483GO:0030520
GeneOntologyBiologicalProcessresponse to amine

CAD RGS9 CPS1

3.34e-0458483GO:0014075
GeneOntologyBiologicalProcesspositive regulation of intracellular estrogen receptor signaling pathway

NCOA3 KMT2D

3.45e-0412482GO:0033148
GeneOntologyBiologicalProcessface development

CHD7 CREBBP EP300

4.26e-0463483GO:0060324
GeneOntologyBiologicalProcesslabyrinthine layer development

NCOA3 NCOA6 NCOA1

4.46e-0464483GO:0060711
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

NCOA3 KMT2D CNOT2 EP300

4.62e-04155484GO:0043401
GeneOntologyBiologicalProcessprotein acetylation

FOXO1 CREBBP EP300

5.33e-0468483GO:0006473
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

6.23e-0416482GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

6.23e-0416482GO:1900034
GeneOntologyBiologicalProcessnon-proteinogenic amino acid biosynthetic process

CAD CPS1

7.05e-0417482GO:0170043
GeneOntologyBiologicalProcesspositive regulation of intracellular steroid hormone receptor signaling pathway

NCOA3 KMT2D

7.92e-0418482GO:0033145
GeneOntologyBiologicalProcessnucleobase biosynthetic process

CAD CPS1

7.92e-0418482GO:0046112
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

NCOA3 SS18 CNOT2

7.96e-0478483GO:2000036
GeneOntologyBiologicalProcessregulation of metal ion transport

CACNA1B MLLT6 RGS9 CHD7 IKBKB GEM

9.48e-04493486GO:0010959
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

BCL9L BCL9 CREBBP EP300

1.03e-03192484GO:0017015
GeneOntologyBiologicalProcesschordate embryonic development

NCOA3 NCOA6 CELSR1 KMT2D NCOA1 CHD7 CNOT2 EP300

1.06e-03906488GO:0043009
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

BCL9L BCL9 CREBBP EP300

1.09e-03195484GO:1903844
GeneOntologyBiologicalProcesspyrimidine nucleobase metabolic process

CAD CPS1

1.19e-0322482GO:0006206
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

NCOA3 NCOA6 CELSR1 KMT2D NCOA1 CHD7 CNOT2 EP300

1.25e-03929488GO:0009792
GeneOntologyCellularComponenttranscription regulator complex

BCL9L NCOA3 NCOA6 GTF2H1 TCF12 DACH2 MED8 NCOA1 BCL9 CREBBP EP300

6.33e-085964711GO:0005667
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

BCL9L NCOA3 GTF2H1 TCF12 MED8 NCOA1 BCL9 CREBBP

1.50e-07272478GO:0090575
GeneOntologyCellularComponentnuclear protein-containing complex

ORC1 BCL9L NCOA3 NCOA6 ARID1B GTF2H1 KMT2D TCF12 NUP155 MED8 TMOD1 NCOA1 BCL9 SS18 CREBBP

1.79e-0713774715GO:0140513
GeneOntologyCellularComponentMLL3/4 complex

NCOA6 KMT2D

3.22e-0412472GO:0044666
GeneOntologyCellularComponentbeta-catenin-TCF complex

BCL9L BCL9

3.80e-0413472GO:1990907
GeneOntologyCellularComponentnpBAF complex

ARID1B SS18

4.43e-0414472GO:0071564
GeneOntologyCellularComponentchromatin

FOXO1 NCOA3 ARID1B TCF12 NCOA1 SHOX CHD7 SS18 CREBBP EP300

1.42e-0314804710GO:0000785
GeneOntologyCellularComponentSWI/SNF complex

ARID1B SS18

2.07e-0330472GO:0016514
HumanPhenoElbow dislocation

ORC1 ARID1B SHOX CHD7 CREBBP EP300

5.41e-0784206HP:0003042
HumanPhenoUpper extremity joint dislocation

ORC1 ARID1B SHOX CHD7 CREBBP EP300

1.20e-0696206HP:0030310
HumanPhenoDislocated radial head

ARID1B SHOX CHD7 CREBBP EP300

1.52e-0654205HP:0003083
HumanPhenoAbnormality of the radial head

ARID1B SHOX CHD7 CREBBP EP300

2.00e-0657205HP:0003995
HumanPhenoAbnormality of the humeroradial joint

ARID1B SHOX CHD7 CREBBP EP300

3.06e-0662205HP:0100744
HumanPhenoPilomatrixoma

KMT2D CREBBP EP300

4.28e-069203HP:0030434
HumanPhenoLong eyelashes

ORC1 ARID1B KMT2D CREBBP CNOT2 EP300

6.80e-06129206HP:0000527
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

1.46e-052202HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

1.46e-052202HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

1.46e-052202HP:0001042
HumanPhenoProminent fingertip pads

ARID1B KMT2D CREBBP EP300

2.54e-0546204HP:0001212
HumanPhenoSquare face

CHD7 CREBBP EP300

2.81e-0516203HP:0000321
HumanPhenoProminent digit pad

ARID1B KMT2D CREBBP EP300

3.01e-0548204HP:0011298
HumanPhenoHypoplastic left heart

KMT2D MYRF CREBBP EP300

3.27e-0549204HP:0004383
HumanPhenoPremature thelarche

KMT2D CREBBP EP300

3.40e-0517203HP:0010314
HumanPhenoCongenital malformation of the left heart

KMT2D MYRF CREBBP EP300

3.84e-0551204HP:0045017
HumanPhenoSkin appendage neoplasm

KMT2D CREBBP EP300

4.07e-0518203HP:0012842
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

4.38e-053202HP:0008752
HumanPhenoPhobia

CREBBP EP300

4.38e-053202HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

4.38e-053202HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

4.38e-053202HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

4.38e-053202HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

4.38e-053202HP:0005895
HumanPhenoHypoplastic heart

KMT2D MYRF CREBBP EP300

4.82e-0554204HP:0001961
HumanPhenoAbnormal patella morphology

ORC1 ARID1B SHOX CREBBP EP300

4.91e-05109205HP:0003045
HumanPhenoAbnormal aortic arch morphology

KMT2D CHD7 MYRF CREBBP EP300

4.91e-05109205HP:0012303
HumanPhenoLocalized hirsutism

ARID1B CREBBP EP300

6.58e-0521203HP:0009889
HumanPhenoInterrupted aortic arch

KMT2D CHD7 MYRF

7.60e-0522203HP:0011611
HumanPhenoTrichiasis

CREBBP EP300

8.75e-054202HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

8.75e-054202HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

8.75e-054202HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

8.75e-054202HP:0006200
HumanPhenoDysplastic tricuspid valve

CHD7 MYRF

8.75e-054202HP:0030732
HumanPhenoScimitar anomaly

KMT2D MYRF

8.75e-054202HP:0011626
HumanPhenoVascular ring

CREBBP EP300

8.75e-054202HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

8.75e-054202HP:0031207
HumanPhenoClinodactyly of the 5th finger

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

1.04e-04420208HP:0004209
HumanPhenoClinodactyly of hands

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

1.05e-04421208HP:0001157
HumanPhenoDeviation of the 5th finger

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

1.05e-04421208HP:0009179
HumanPhenoShawl scrotum

ORC1 CREBBP EP300

1.13e-0425203HP:0000049
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

1.45e-045202HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

1.45e-045202HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

1.45e-045202HP:0030421
HumanPhenoRadial deviation of finger

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

1.64e-04448208HP:0009466
HumanPhenoFinger clinodactyly

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

1.74e-04452208HP:0040019
HumanPhenoShort columella

KMT2D CREBBP EP300

1.77e-0429203HP:0002000
HumanPhenoAbnormal scrotum morphology

ORC1 CHD7 MYRF CREBBP EP300

1.79e-04143205HP:0000045
HumanPhenoRadial deviation of the hand or of fingers of the hand

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

1.86e-04456208HP:0009485
HumanPhenoLarge foramen magnum

CREBBP EP300

2.18e-046202HP:0002700
HumanPhenoAplasia/Hypoplasia of the patella

ORC1 ARID1B SHOX

2.62e-0433203HP:0006498
HumanPhenoAbnormal branching pattern of the aortic arch

CHD7 CREBBP EP300

2.62e-0433203HP:0011587
HumanPhenoIntestinal malrotation

ARID1B KMT2D MYRF CREBBP EP300

2.78e-04157205HP:0002566
HumanPhenoSupernumerary tooth

KMT2D TCF12 CREBBP EP300

2.85e-0485204HP:0011069
HumanPhenoDeviated nasal septum

CREBBP EP300

3.04e-047202HP:0004411
HumanPhenoHydrocele testis

KMT2D CREBBP EP300

3.40e-0436203HP:0000034
HumanPhenoNasolacrimal duct obstruction

KMT2D CREBBP EP300

3.40e-0436203HP:0000579
HumanPhenoAccessory spleen

MYRF CREBBP EP300

3.69e-0437203HP:0001747
HumanPhenoHypospadias

ORC1 ARID1B KMT2D TCF12 MYRF CREBBP EP300

3.83e-04377207HP:0000047
HumanPhenoAbnormal palmar dermatoglyphics

ARID1B KMT2D TCF12 CHD7 CREBBP EP300

3.91e-04265206HP:0001018
HumanPhenoAbnormal 5th finger morphology

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

3.99e-04509208HP:0004207
HumanPhenoNatal tooth

KMT2D CREBBP EP300

4.00e-0438203HP:0000695
HumanPhenoJoint dislocation

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP EP300

4.71e-04390207HP:0001373
HumanPhenoCervical cord compression

CREBBP EP300

5.19e-049202HP:0002341
HumanPhenoDisplacement of the urethral meatus

ORC1 ARID1B KMT2D TCF12 MYRF CREBBP EP300

5.26e-04397207HP:0100627
HumanPhenoAbnormal male urethral meatus morphology

ORC1 ARID1B KMT2D TCF12 MYRF CREBBP EP300

5.42e-04399207HP:0032076
HumanPhenoAbnormality of the elbow

ORC1 ARID1B SHOX CHD7 CREBBP EP300

5.47e-04282206HP:0009811
HumanPhenoAbnormal eyelash morphology

ORC1 ARID1B KMT2D CREBBP CNOT2 EP300

5.68e-04284206HP:0000499
HumanPhenoDeviation of finger

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

5.77e-04537208HP:0004097
HumanPhenoJuvenile aseptic necrosis

ORC1 CREBBP EP300

5.78e-0443203HP:0100323
HumanPhenoAplasia/hypoplasia involving bones of the hand

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

5.84e-04538208HP:0005927
HumanPhenoFrontal hirsutism

CREBBP EP300

6.47e-0410202HP:0011335
HumanPhenoAdvanced eruption of teeth

KMT2D CREBBP EP300

7.06e-0446203HP:0006288
HumanPhenoAbnormal dental morphology

ORC1 ARID1B KMT2D TCF12 CREBBP EP300

7.47e-04299206HP:0006482
HumanPhenoPartial anomalous pulmonary venous return

KMT2D MYRF

7.89e-0411202HP:0010773
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

7.89e-0411202HP:0031251
HumanPhenoChiari type I malformation

KMT2D CREBBP EP300

8.00e-0448203HP:0007099
HumanPhenoDeviation of the hand or of fingers of the hand

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

8.05e-04564208HP:0009484
HumanPhenoAbnormal femur morphology

ORC1 ARID1B SHOX CHD7 CREBBP EP300

8.16e-04304206HP:0002823
HumanPhenoAbnormal femoral neck/head morphology

ORC1 ARID1B SHOX CREBBP EP300

8.69e-04201205HP:0003366
HumanPhenoAbnormal toe morphology

ORC1 ARID1B KMT2D TCF12 SHOX CHD7 MYRF CREBBP CNOT2 EP300

8.82e-048932010HP:0001780
HumanPhenoAplasia/hypoplasia involving bones of the upper limbs

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

8.85e-04572208HP:0006496
HumanPhenoAbnormal lacrimal duct morphology

KMT2D CREBBP EP300

9.02e-0450203HP:0011481
HumanPhenoClinodactyly

ORC1 ARID1B KMT2D SHOX CHD7 CREBBP CNOT2 EP300

9.07e-04574208HP:0030084
HumanPhenoDuodenal ulcer

ARID1B EP300

9.44e-0412202HP:0002588
HumanPhenoHypoplasia of the phalanges of the toes

ARID1B EP300

9.44e-0412202HP:0010746
HumanPhenoSelf-mutilation

CHD7 CREBBP EP300

9.56e-0451203HP:0000742
HumanPhenoAbnormal dermatoglyphics

ARID1B KMT2D TCF12 CHD7 CREBBP EP300

9.69e-04314206HP:0007477
HumanPhenoAplasia/Hypoplasia of the earlobes

CHD7 CREBBP EP300

1.07e-0353203HP:0009906
HumanPhenoAbnormality of the thigh

ORC1 ARID1B SHOX CHD7 CREBBP EP300

1.11e-03322206HP:0001439
HumanPhenoFacial grimacing

CREBBP EP300

1.11e-0313202HP:0000273
HumanPhenoKeloids

CREBBP EP300

1.11e-0313202HP:0010562
HumanPhenoShort finger

ARID1B KMT2D CHD7 CREBBP CNOT2 EP300

1.16e-03325206HP:0009381
HumanPhenoSingle transverse palmar crease

ARID1B KMT2D TCF12 CREBBP EP300

1.18e-03215205HP:0000954
HumanPhenoHirsutism

ARID1B KMT2D CREBBP CNOT2 EP300

1.20e-03216205HP:0001007
HumanPhenoAbnormal morphology of the radius

ARID1B SHOX CHD7 CREBBP EP300

1.23e-03217205HP:0002818
HumanPhenoLow hanging columella

KMT2D CREBBP EP300

1.26e-0356203HP:0009765
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

1.30e-0314202HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

1.30e-0314202HP:0012304
HumanPhenoParietal foramina

CREBBP EP300

1.30e-0314202HP:0002697
HumanPhenoAbnormality of the urethra

ORC1 ARID1B KMT2D TCF12 MYRF CREBBP EP300

1.36e-03465207HP:0000795
MousePhenodecreased circulating glucagon level

CACNA1B NCOA3 CREBBP

1.89e-0520373MP:0002696
MousePhenoabnormal hypothalamus physiology

CACNA1B ARID1B CHD7

4.26e-0526373MP:0005645
MousePhenoembryonic lethality during organogenesis, complete penetrance

FOXO1 BCL9L NCOA6 KMT2D TMOD1 CHD7 IKBKB CREBBP EP300

6.60e-05700379MP:0011098
MousePhenothin myocardium

NCOA6 TMOD1 CHD7 EP300

7.22e-0585374MP:0002652
MousePhenoabnormal embryonic growth/weight/body size

FOXO1 BCL9L NCOA3 NCOA6 RBM12 TMOD1 CHD7 BCL9 SS18 MYRF CREBBP EP300

7.83e-0512953712MP:0002088
MousePhenoembryonic growth retardation

FOXO1 NCOA6 RBM12 TMOD1 CHD7 SS18 MYRF CREBBP EP300

1.28e-04763379MP:0003984
MousePhenoabnormal circulating glucagon level

CACNA1B NCOA3 CREBBP

1.58e-0440373MP:0002695
MousePhenoabsent organized vascular network

FOXO1 CREBBP

1.89e-048372MP:0000263
MousePhenopericardial effusion

FOXO1 NCOA6 TMOD1 EP300

2.03e-04111374MP:0005312
MousePhenothin myocardium compact layer

NCOA6 CREBBP EP300

2.40e-0446373MP:0004057
MousePhenodecreased circulating free fatty acids level

FOXO1 NCOA3 CHD7 CREBBP

2.41e-04116374MP:0002702
MousePhenoembryonic growth arrest

BCL9L TMOD1 CHD7 SS18 CREBBP EP300

2.68e-04346376MP:0001730
MousePhenoopen neural tube

CELSR1 RBM12 SS18 CREBBP EP300

3.02e-04226375MP:0000929
MousePhenoabnormal prenatal growth/weight/body size

FOXO1 BCL9L NCOA3 NCOA6 RBM12 TMOD1 CHD7 BCL9 SS18 MYRF CREBBP EP300

3.05e-0414933712MP:0004196
MousePhenoprenatal growth retardation

FOXO1 NCOA6 RBM12 TMOD1 CHD7 SS18 MYRF CREBBP EP300

3.41e-04869379MP:0010865
MousePhenoembryonic lethality during organogenesis

FOXO1 BCL9L NCOA6 KMT2D TMOD1 CHD7 IKBKB CREBBP EP300

3.61e-04876379MP:0006207
MousePhenoabnormal vitelline vasculature morphology

FOXO1 NCOA6 TMOD1 CREBBP EP300

3.62e-04235375MP:0003229
MousePhenoabnormal vasculogenesis

FOXO1 CREBBP EP300

3.86e-0454373MP:0001622
MousePhenoabnormal heart development

FOXO1 NCOA6 TMOD1 CHD7 CREBBP EP300

3.94e-04372376MP:0000267
MousePhenoflattened snout

KMT2D CREBBP

4.42e-0412372MP:0000447
MousePhenodecreased circulating hormone level

CACNA1B NCOA3 ARID1B SGTA NCOA1 CHD7 CREBBP

5.23e-04551377MP:0014457
MousePhenoabnormal myocardial trabeculae morphology

FOXO1 NCOA6 TMOD1 EP300

5.48e-04144374MP:0002189
MousePhenodecreased circulating insulin-like growth factor I level

NCOA3 ARID1B SGTA

5.53e-0461373MP:0004701
MousePhenoabnormal embryo development

FOXO1 BCL9L NCOA6 RBM12 NUP155 TMOD1 CHD7 SS18 MYRF CREBBP EP300

5.95e-0413703711MP:0001672
MousePhenodecreased fatty acids level

FOXO1 NCOA3 CHD7 CREBBP

6.55e-04151374MP:0005282
MousePhenoeffusion

FOXO1 NCOA6 TMOD1 EP300

6.71e-04152374MP:0021205
MousePhenoabnormal fibroblast physiology

ORC1 NCOA3 NCOA6 IKBKB EP300

6.92e-04271375MP:0020414
MousePhenoabnormal myocardium layer morphology

FOXO1 NCOA6 TMOD1 CHD7 CREBBP EP300

6.94e-04414376MP:0005329
MousePhenoabnormal chorionic plate morphology

BCL9L SS18

7.00e-0415372MP:0004560
MousePhenoabnormal myocardium compact layer morphology

NCOA6 CREBBP EP300

7.28e-0467373MP:0004056
MousePhenoabnormal carbon dioxide production

FOXO1 NCOA3 CHD7

7.28e-0467373MP:0008962
MousePhenoabnormal heart layer morphology

FOXO1 NCOA6 TMOD1 CHD7 CREBBP EP300

7.67e-04422376MP:0010545
MousePhenodecreased susceptibility to diet-induced obesity

CACNA1B NCOA3 KMT2D CREBBP

8.13e-04160374MP:0005659
MousePhenoventricle myocardium hypoplasia

NCOA6 CREBBP EP300

8.62e-0471373MP:0010502
MousePhenoabnormal gas homeostasis

FOXO1 NCOA3 ZNF536 CHD7 SS18 CREBBP EP300

8.67e-04600377MP:0003948
MousePhenoabnormal circulating insulin-like growth factor I level

NCOA3 ARID1B SGTA

8.98e-0472373MP:0004700
MousePhenoabsent olfactory bulb

NCOA6 CHD7

9.04e-0417372MP:0003451
MousePhenoabnormal epicardium morphology

NCOA6 EP300

9.04e-0417372MP:0003057
MousePhenoincreased grooming behavior

ARID1B KMT2D CREBBP

9.72e-0474373MP:0001441
MousePhenoabnormal insulin-like growth factor I level

NCOA3 ARID1B SGTA

1.01e-0375373MP:0008831
MousePhenodecreased fetal cardiomyocyte proliferation

NCOA6 CHD7

1.02e-0318372MP:0011395
MousePhenohypoalgesia

CACNA1B ARID1B KMT2D CHD7

1.02e-03170374MP:0003043
MousePhenodecreased hormone level

CACNA1B NCOA3 ARID1B SGTA NCOA1 CHD7 CREBBP

1.21e-03635377MP:0014455
MousePhenoabnormal nervous system development

NCOA6 CELSR1 ARID1B RBM12 TCF12 NCOA1 CHD7 SS18 CREBBP EP300

1.21e-0312573710MP:0003861
MousePhenoabnormal susceptibility to weight gain

FOXO1 CACNA1B NCOA3 KMT2D CREBBP

1.25e-03309375MP:0011117
MousePhenothin ventricle myocardium compact layer

CREBBP EP300

1.26e-0320372MP:0010556
MousePhenoabnormal liver glycogen level

FOXO1 NCOA3 CREBBP

1.26e-0381373MP:0012777
MousePhenoabnormal energy expenditure

FOXO1 CACNA1B NCOA3 KMT2D CREBBP

1.32e-03313375MP:0005450
MousePhenodecreased susceptibility to weight gain

CACNA1B NCOA3 KMT2D CREBBP

1.42e-03186374MP:0010182
MousePhenoabnormal energy homeostasis

FOXO1 CACNA1B NCOA3 KMT2D CREBBP

1.50e-03322375MP:0005448
MousePhenomyocardium hypoplasia

NCOA6 CREBBP EP300

1.50e-0386373MP:0010500
MousePhenohead shaking

CELSR1 CHD7

1.52e-0322372MP:0002730
MousePhenoabsent myocardial trabeculae

TMOD1 EP300

1.52e-0322372MP:0000293
DomainNuc_rcpt_coact

NCOA3 NCOA1 CREBBP EP300

5.74e-106484IPR009110
DomainCPSase_sm_chain

CAD CPS1

6.47e-062482PF00988
DomainBCL9_beta-catenin-bd_dom

BCL9L BCL9

6.47e-062482IPR024670
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

6.47e-062482IPR014744
DomainHAT_KAT11

CREBBP EP300

6.47e-062482PF08214
DomainKIX

CREBBP EP300

6.47e-062482PS50952
DomainBCL9

BCL9L BCL9

6.47e-062482PF11502
DomainZnF_TAZ

CREBBP EP300

6.47e-062482SM00551
DomainCBP_P300_HAT

CREBBP EP300

6.47e-062482IPR031162
DomainDUF902

CREBBP EP300

6.47e-062482PF06001
DomainCPSase_L_D3

CAD CPS1

6.47e-062482PF02787
Domain-

CREBBP EP300

6.47e-0624821.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

6.47e-062482IPR010303
Domain-

CREBBP EP300

6.47e-0624821.10.1630.10
DomainCreb_binding

CREBBP EP300

6.47e-062482PF09030
DomainCarbamoylP_synth_ssu

CAD CPS1

6.47e-062482IPR006274
DomainCarbamoylP_synth_lsu

CAD CPS1

6.47e-062482IPR006275
Domain-

CREBBP EP300

6.47e-0624821.10.246.20
Domainzf-TAZ

CREBBP EP300

6.47e-062482PF02135
Domain-

CAD CPS1

6.47e-0624823.50.30.20
DomainZF_TAZ

CREBBP EP300

6.47e-062482PS50134
DomainCPSase_sm_chain

CAD CPS1

6.47e-062482SM01097
DomainCPSase_L_D3

CAD CPS1

6.47e-062482SM01096
DomainCbamoylP_synth_lsu_CPSase_dom

CAD CPS1

6.47e-062482IPR005483
DomainCarbamoylP_synth_lsu_oligo

CAD CPS1

6.47e-062482IPR005480
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

6.47e-062482IPR013178
Domain-

CAD CPS1

6.47e-0624821.10.1030.10
DomainKAT11

CREBBP EP300

6.47e-062482SM01250
DomainZnf_TAZ

CREBBP EP300

6.47e-062482IPR000197
DomainKIX_dom

CREBBP EP300

6.47e-062482IPR003101
DomainKIX

CREBBP EP300

6.47e-062482PF02172
DomainCarbamoylP_synth_ssu_N

CAD CPS1

6.47e-062482IPR002474
DomainBcl-9

BCL9L BCL9

6.47e-062482IPR015668
DomainCBP_P300_HAT

CREBBP EP300

6.47e-062482PS51727
DomainDUF1518

NCOA3 NCOA1

1.94e-053482PF07469
DomainDUF1518

NCOA3 NCOA1

1.94e-053482IPR010011
DomainNuc_rcpt_coact_Ncoa-typ

NCOA3 NCOA1

1.94e-053482IPR014920
DomainSRC-1

NCOA3 NCOA1

1.94e-053482IPR014935
DomainMGS

CAD CPS1

1.94e-053482SM00851
DomainMGS-like_dom

CAD CPS1

1.94e-053482IPR011607
DomainMGS

CAD CPS1

1.94e-053482PF02142
Domain-

CAD CPS1

1.94e-0534823.40.50.1380
DomainSrc1_rcpt_coact

NCOA3 NCOA1

1.94e-053482IPR008955
DomainNuclear_rcpt_coactivator

NCOA3 NCOA1

1.94e-053482IPR017426
DomainDUF1518

NCOA3 NCOA1

1.94e-053482SM01151
DomainSRC-1

NCOA3 NCOA1

1.94e-053482PF08832
Domain-

NCOA3 NCOA1

1.94e-0534824.10.630.10
DomainNuc_rec_co-act

NCOA3 NCOA1

1.94e-053482PF08815
DomainGATase

CAD CPS1

6.44e-055482PF00117
DomainCPSASE_1

CAD CPS1

6.44e-055482PS00866
DomainGATASE

CAD CPS1

9.64e-056482IPR017926
DomainCPSASE_2

CAD CPS1

9.64e-056482PS00867
DomainGATASE_TYPE_1

CAD CPS1

9.64e-056482PS51273
DomainCPSase_L_D2

CAD CPS1

1.35e-047482PF02786
DomainCbamoylP_synth_lsu-like_ATP-bd

CAD CPS1

1.35e-047482IPR005479
DomainBC-like_N

CAD CPS1

1.35e-047482IPR005481
DomainBiotin_carb_N

CAD CPS1

1.35e-047482PF00289
Domain-

CAD CPS1

2.87e-04104823.40.50.880
DomainClass_I_gatase-like

CAD CPS1

4.20e-0412482IPR029062
Domain-

CAD CPS1

4.95e-04134823.40.50.20
DomainATP-grasp

CAD CPS1

5.77e-0414482IPR011761
DomainPreATP-grasp_dom

CAD CPS1

5.77e-0414482IPR016185
DomainATP_GRASP

CAD CPS1

5.77e-0414482PS50975
Domain-

CAD CPS1

6.65e-04154823.30.1490.20
DomainZZ

CREBBP EP300

9.64e-0418482PF00569
DomainATP_grasp_subdomain_1

CAD CPS1

9.64e-0418482IPR013815
DomainZF_ZZ_2

CREBBP EP300

9.64e-0418482PS50135
DomainZF_ZZ_1

CREBBP EP300

9.64e-0418482PS01357
Domain-

CAD CPS1

9.64e-04184823.30.470.20
DomainZnf_ZZ

CREBBP EP300

1.08e-0319482IPR000433
DomainZnF_ZZ

CREBBP EP300

1.08e-0319482SM00291
DomainEPHD

KMT2D MLLT6

1.45e-0322482PS51805
DomainPAS

NCOA3 NCOA1

1.87e-0325482PF00989
DomainPAS_fold

NCOA3 NCOA1

1.87e-0325482IPR013767
DomainBromodomain_CS

CREBBP EP300

2.02e-0326482IPR018359
Domain-

NCOA3 TCF12 NCOA1

2.76e-031094834.10.280.10
DomainATP_grasp_subdomain_2

CAD CPS1

2.87e-0331482IPR013816
DomainHLH

NCOA3 TCF12 NCOA1

2.91e-03111483PF00010
DomainPAS

NCOA3 NCOA1

3.05e-0332482SM00091
DomainHLH

NCOA3 TCF12 NCOA1

3.29e-03116483SM00353
DomainBHLH

NCOA3 TCF12 NCOA1

3.38e-03117483PS50888
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

NCOA3 NCOA6 MED8 NCOA1 CREBBP EP300

5.28e-0884356M1008
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA6 NCOA1 CREBBP EP300

9.50e-0818354M26942
PathwayREACTOME_ADIPOGENESIS

NCOA3 NCOA6 MED8 NCOA1 CREBBP EP300

2.66e-07110356M48259
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA3 NCOA6 MED8 NCOA1 CREBBP EP300

4.03e-07118356M27316
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L KMT2D BCL9 EP300

4.58e-0726354MM14793
PathwayBIOCARTA_PPARG_PATHWAY

NCOA1 CREBBP EP300

7.79e-078353M22058
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA3 NCOA1 CREBBP EP300

8.33e-0730354M207
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

FOXO1 CREBBP EP300

1.66e-0610353M27945
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L KMT2D BCL9 CREBBP EP300

2.80e-0691355M27101
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

FOXO1 NCOA3 NCOA1 CREBBP EP300

2.80e-0691355M39700
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

FOXO1 MAML2 CREBBP EP300

3.33e-0642354M17541
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML2 CREBBP EP300

5.01e-0614353M27808
PathwayPID_HES_HEY_PATHWAY

NCOA1 MAML2 CREBBP EP300

5.73e-0648354M288
PathwayREACTOME_HEME_SIGNALING

NCOA6 NCOA1 CREBBP EP300

6.23e-0649354M41832
PathwayPID_FOXO_PATHWAY

FOXO1 IKBKB CREBBP EP300

6.23e-0649354M136
PathwayBIOCARTA_RELA_PATHWAY

IKBKB CREBBP EP300

6.25e-0615353MM1339
PathwayBIOCARTA_RELA_PATHWAY

IKBKB CREBBP EP300

6.25e-0615353M10183
PathwayWP_RUBINSTEINTAYBI_SYNDROME_1

FOXO1 NCOA3 CREBBP

6.25e-0615353M48323
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

MAML2 CREBBP EP300

7.68e-0616353M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

FOXO1 CREBBP EP300

7.68e-0616353M27940
PathwayPID_AR_TF_PATHWAY

FOXO1 NCOA1 CREBBP EP300

8.55e-0653354M151
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

NCOA3 NCOA6 KMT2D CREBBP EP300

1.18e-05122355M29689
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 CREBBP EP300

1.55e-0520353M27881
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

FOXO1 NCOA3 NCOA6 ARID1B KMT2D TCF12 MED8 NCOA1 MAML2 SS18 CREBBP CNOT2 EP300

2.01e-0514323513M509
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

FOXO1 ABCA6 CREBBP EP300

2.06e-0566354M27938
PathwayBIOCARTA_VDR_PATHWAY

NCOA3 CREBBP EP300

2.09e-0522353MM1370
PathwayBIOCARTA_NTHI_PATHWAY

IKBKB CREBBP EP300

2.09e-0522353MM1443
PathwayBIOCARTA_NTHI_PATHWAY

IKBKB CREBBP EP300

2.40e-0523353M2821
PathwayREACTOME_CIRCADIAN_CLOCK

NCOA6 NCOA1 CREBBP EP300

2.60e-0570354M938
PathwayBIOCARTA_VDR_PATHWAY

NCOA1 CREBBP EP300

2.74e-0524353M13404
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 CREBBP EP300

3.11e-0525353M27880
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

NCOA6 ARID1B GTF2H1 KMT2D SS18 EP300

3.38e-05254356M27131
PathwayPID_HDAC_CLASSIII_PATHWAY

FOXO1 CREBBP EP300

3.51e-0526353M32
PathwayWP_ESTROGEN_SIGNALING

GTF2H1 IKBKB CREBBP EP300

3.79e-0577354MM15934
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA6 NCOA1 CREBBP

3.94e-0527353M26943
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

FOXO1 NCOA1 CREBBP EP300

4.85e-0582354M2
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

5.96e-055352MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

5.96e-055352M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

5.96e-055352M48023
PathwayKEGG_MEDICUS_VARIANT_ESR1_POSITIVE_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA3 NCOA1

5.96e-055352M48983
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

5.96e-055352M27228
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

FOXO1 NCOA6 NCOA1

6.01e-0531353M39476
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

FOXO1 NCOA3 NCOA1

6.62e-0532353M39567
PathwayKEGG_PROSTATE_CANCER

FOXO1 IKBKB CREBBP EP300

6.69e-0589354M13191
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

FOXO1 ARID1B GTF2H1 KMT2D TCF12 ABCA6 MED8 MAML2 CREBBP GEM CNOT2 EP300

7.61e-0513873512M734
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

8.93e-056352M22062
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

FOXO1 EP300

8.93e-056352MM15660
PathwayWP_IL6_SIGNALING_PATHWAY

FOXO1 NCOA1 CREBBP EP300

1.05e-04100354MM15826
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.25e-047352MM1573
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

NCOA6 NCOA1 CREBBP

1.51e-0442353M27172
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

BCL9L KMT2D BCL9

1.51e-0442353M27272
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

1.66e-048352M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

1.66e-048352M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

1.66e-048352M46443
PathwayPID_HNF3A_PATHWAY

NCOA3 CREBBP EP300

1.73e-0444353M285
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOA1 CREBBP EP300

1.73e-0444353M27295
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

MAML2 CREBBP EP300

2.11e-0447353M7946
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

2.13e-049352M47451
PathwayWP_ENERGY_METABOLISM

FOXO1 NCOA1 EP300

2.25e-0448353M39590
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 CREBBP EP300

2.25e-0448353M611
PathwayREACTOME_SIGNALING_BY_NOTCH3

MAML2 CREBBP EP300

2.39e-0449353M618
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L KMT2D BCL9 CREBBP EP300

2.56e-04233355M27099
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML2 EP300

2.66e-0410352MM15535
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

ARID1B KMT2D TCF12 CREBBP EP300

2.77e-04237355M27786
PathwayBIOCARTA_PPARA_PATHWAY

NCOA1 CREBBP EP300

2.85e-0452353M2404
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

3.25e-0411352MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

3.25e-0411352M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

3.25e-0411352M26924
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA3 NCOA1

3.25e-0411352M47503
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

NCOA6 NCOA1 CREBBP

3.37e-0455353M27145
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

NCOA6 NCOA1 CREBBP

3.37e-0455353M27001
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

3.89e-0412352M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

3.89e-0412352M27765
PathwayREACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 EP300

3.89e-0412352M27159
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

MAML2 CREBBP EP300

3.94e-0458353M29616
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

NCOA6 NCOA1 CREBBP

4.35e-0460353M41830
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOA1 EP300

4.59e-0413352MM15622
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

NCOA3 NCOA1 CREBBP EP300

4.86e-04149354M27888
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

ARID1B KMT2D NCOA1 CREBBP EP300

5.21e-04272355M29619
PathwayPID_ERA_GENOMIC_PATHWAY

NCOA3 NCOA1 EP300

5.27e-0464353M200
PathwayREACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA

IKBKB CREBBP EP300

5.27e-0464353M27046
PathwayPID_HIF1_TFPATHWAY

NCOA1 CREBBP EP300

5.76e-0466353M255
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L KMT2D BCL9 EP300

6.07e-04158354MM14791
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

6.16e-0415352MM1439
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA3 NCOA1

6.16e-0415352M119
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

6.16e-0415352M953
PathwayWP_RAC1PAK1P38MMP2_PATHWAY

FOXO1 ANGPT4 IKBKB

6.29e-0468353M39456
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

IKBKB CREBBP EP300

6.57e-0469353M48052
PathwayREACTOME_FORMATION_OF_PARAXIAL_MESODERM

MAML2 CREBBP EP300

6.57e-0469353M46439
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

7.03e-0416352M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

7.03e-0416352MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

7.03e-0416352M8516
PathwayPID_E2F_PATHWAY

ORC1 CREBBP EP300

7.74e-0473353M40
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

7.96e-0417352MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

7.96e-0417352M48025
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML2 CREBBP EP300

8.05e-0474353M616
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

KMT2D CAD NCOA1 CREBBP EP300

8.24e-04301355MM15983
PathwayWP_LEPTIN_SIGNALING

FOXO1 NCOA1 IKBKB

8.71e-0476353M39491
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML2 EP300

8.94e-0418352MM14775
PathwayPID_MYC_ACTIV_PATHWAY

CAD CREBBP EP300

9.74e-0479353M66
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

BCL9L NCOA3 NCOA6 ARID1B KMT2D RBM12 MED8 NCOA1 CHD7 BCL9 CREBBP

8.13e-14268481133640491
Pubmed

Human transcription factor protein interaction networks.

BCL9L NCOA3 NCOA6 ZNF536 ARID1B KMT2D CAD RBM12 TCF12 MED8 NCOA1 MLLT6 CHD7 BCL9 SS18 CREBBP CNOT2 EP300

2.27e-131429481835140242
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA3 NCOA6 ZNF536 ARID1B KMT2D CHD7 BCL9 EP300

2.60e-138348828794006
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA3 NCOA6 NCOA1 IKBKB CREBBP EP300

2.67e-132148619596656
Pubmed

Interaction network of human early embryonic transcription factors.

BCL9L NCOA3 NCOA6 ZNF536 ARID1B KMT2D NCOA1 CHD7 BCL9 CREBBP EP300

1.53e-12351481138297188
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

BCL9L NCOA3 NCOA6 ARID1B KMT2D RBM12 NUP155 BCL9 CREBBP CNOT2 EP300

2.61e-11457481132344865
Pubmed

Temporal/spatial expression of nuclear receptor coactivators in the mouse lung.

NCOA3 NCOA1 CREBBP EP300

4.78e-11648411076796
Pubmed

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells.

FOXO1 NCOA1 CREBBP EP300

4.78e-11648410973497
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA3 NCOA6 ZNF536 ARID1B KMT2D MED8 NCOA1 CHD7 BCL9 SS18 CREBBP EP300

5.00e-11638481231182584
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOA3 NCOA6 NCOA1 CREBBP EP300

6.17e-112048511877444
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA3 NCOA6 ARID1B KMT2D CAD RBM12 TCF12 MED8 NCOA1 MLLT6 CHD7 BCL9 CREBBP EP300

1.69e-101103481434189442
Pubmed

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

NCOA3 NCOA1 IKBKB CREBBP

2.23e-10848411971985
Pubmed

Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression.

NCOA3 NCOA1 CREBBP EP300

2.23e-10848417475621
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOA3 NCOA6 ARID1B KMT2D NCOA1 CHD7

1.19e-097848628611094
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

NCOA6 NCOA1 CREBBP EP300

1.57e-091248412189208
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

NCOA3 CAD NCOA1 IKBKB CREBBP EP300

2.01e-098548616051665
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

NCOA6 ARID1B KMT2D CHD7 SS18 CREBBP EP300

2.10e-0915748730186101
Pubmed

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.

NCOA3 CREBBP EP300

2.47e-09348311823864
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

NCOA6 KMT2D NCOA1 CREBBP

3.16e-091448412482968
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOA3 NCOA1 CREBBP EP300

7.50e-091748419183483
Pubmed

Steroid receptor coactivator-1 and its family members differentially regulate transactivation by the tumor suppressor protein p53.

NCOA3 NCOA1 CREBBP

9.86e-09448310551785
Pubmed

Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).

NCOA3 CREBBP EP300

9.86e-09448316227615
Pubmed

Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma.

NCOA3 CREBBP EP300

9.86e-09448333589584
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2D CREBBP EP300

9.86e-09448328398509
Pubmed

Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.

NCOA1 CREBBP EP300

9.86e-09448312208951
Pubmed

The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.

NCOA1 CREBBP EP300

9.86e-09448311463834
Pubmed

CBP/p300 interact with and function as transcriptional coactivators of BRCA1.

NCOA3 CREBBP EP300

9.86e-09448310655477
Pubmed

Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1.

NCOA1 CREBBP EP300

9.86e-09448311113179
Pubmed

A transcriptional switch mediated by cofactor methylation.

NCOA3 CREBBP EP300

9.86e-09448311701890
Pubmed

Mutation of a lysine residue in a homeodomain generates dominant negative thyroid transcription factor 1.

NCOA3 NCOA1 CREBBP

9.86e-09448315449938
Pubmed

New nomenclature for chromatin-modifying enzymes.

NCOA3 KMT2D NCOA1 CREBBP EP300

1.60e-085748518022353
Pubmed

Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF).

GTF2H1 CREBBP EP300

2.46e-08548321670263
Pubmed

Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

NCOA3 NCOA1 EP300

2.46e-08548312714702
Pubmed

Transcription factor-specific requirements for coactivators and their acetyltransferase functions.

NCOA3 NCOA1 CREBBP

2.46e-0854839445475
Pubmed

A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP.

NCOA1 CREBBP EP300

2.46e-08548314722092
Pubmed

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

NCOA3 NCOA1 EP300

2.46e-0854839812974
Pubmed

Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation.

NCOA6 CREBBP EP300

2.46e-08548311912212
Pubmed

Lysine 246 of the vitamin D receptor is crucial for ligand-dependent interaction with coactivators and transcriptional activity.

NCOA3 NCOA1 CREBBP

2.46e-08548310224118
Pubmed

Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins.

NCOA3 NCOA1 CREBBP

4.92e-08648310777539
Pubmed

Role of CBP in regulating HIF-1-mediated activation of transcription.

NCOA1 CREBBP EP300

4.92e-08648315615775
Pubmed

Roles of coactivators in hypoxic induction of the erythropoietin gene.

NCOA3 NCOA1 EP300

4.92e-08648320368990
Pubmed

Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.

NCOA3 NCOA1 EP300

4.92e-08648316923966
Pubmed

Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation.

NCOA1 CREBBP EP300

4.92e-08648310497212
Pubmed

CBP-mediated FOXO-1 acetylation inhibits pancreatic tumor growth by targeting SirT.

FOXO1 CREBBP EP300

4.92e-08648324419059
Pubmed

Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation.

MAML2 CREBBP EP300

4.92e-08648315961999
Pubmed

Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

NCOA3 NCOA1 CREBBP EP300

6.38e-082848424880616
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA3 RBM12 NCOA1 BCL9 CREBBP EP300

6.66e-0815248638360978
Pubmed

BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells.

NCOA3 NCOA1 CREBBP

8.60e-08748316860316
Pubmed

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.

NCOA3 NCOA1 CREBBP

8.60e-0874839192892
Pubmed

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

NCOA1 CREBBP EP300

8.60e-0874839590696
Pubmed

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine.

NCOA3 NCOA1 EP300

8.60e-08748312709428
Pubmed

The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment.

NCOA3 NCOA1 EP300

1.37e-07848312082103
Pubmed

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.

NCOA3 NCOA1 CREBBP

1.37e-0784838616895
Pubmed

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.

NCOA3 CREBBP EP300

1.37e-07848310490106
Pubmed

TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1.

NCOA3 NCOA1 CREBBP

2.06e-0794839346901
Pubmed

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.

NCOA3 ARID1B MAML2

2.06e-07948319176441
Pubmed

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.

NCOA3 ARID1B CREBBP

2.94e-071048316751102
Pubmed

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.

NCOA1 CREBBP EP300

2.94e-071048330595551
Pubmed

Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation.

NCOA3 IKBKB CREBBP

2.94e-071048315808510
Pubmed

Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein.

NCOA3 CREBBP EP300

2.94e-071048311163245
Pubmed

Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

NCOA1 CREBBP EP300

4.04e-071148310454579
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

NCOA1 CREBBP EP300

4.04e-071148315681609
Pubmed

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

NCOA3 NCOA6 NCOA1

4.04e-071148336613751
Pubmed

Congenital Diaphragmatic Hernia Overview

ARID1B KMT2D CHD7 MYRF

4.99e-074648420301533
Pubmed

Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways.

NCOA3 IKBKB CREBBP

5.38e-071248315383283
Pubmed

Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.

NCOA3 CREBBP EP300

5.38e-071248314645221
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

NCOA3 ARID1B KMT2D RBM12 NCOA1 EP300

5.88e-0722048635785414
Pubmed

Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.

NCOA3 NCOA1 CREBBP

6.99e-071348311266503
Pubmed

MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.

NCOA1 CREBBP EP300

8.88e-071448317641689
Pubmed

Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.

NCOA3 NCOA1 EP300

8.88e-071448311500849
Pubmed

E protein silencing by the leukemogenic AML1-ETO fusion protein.

TCF12 CREBBP EP300

8.88e-071448315333839
Pubmed

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.

NCOA3 CREBBP EP300

1.11e-06154839267036
Pubmed

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

NCOA6 NCOA1 CREBBP

1.11e-061548310567404
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOA3 ARID1B KMT2D NCOA1 CHD7 CREBBP EP300

1.20e-0639848735016035
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

FOXO1 NCOA3 NCOA6 NCOA1 CREBBP EP300

1.24e-0625048618660489
Pubmed

A human RNA polymerase II complex containing factors that modify chromatin structure.

GTF2H1 CREBBP EP300

1.36e-06164839710619
Pubmed

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.

NCOA6 CREBBP EP300

1.65e-061748328291835
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

BCL9L NCOA3 NCOA6 MED8 BCL9 CREBBP EP300

1.85e-0642548724999758
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

1.87e-06248227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

1.87e-06248234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

1.87e-06248219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

1.87e-06248215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

1.87e-06248229460469
Pubmed

Quantifying Protection in Disordered Proteins Using Millisecond Hydrogen Exchange-Mass Spectrometry and Peptic Reference Peptides.

NCOA3 CREBBP

1.87e-06248228675294
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

1.87e-06248224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

1.87e-06248233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

1.87e-0624829018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

1.87e-06248224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

1.87e-06248230135524
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

1.87e-06248239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

1.87e-06248216596650
Pubmed

The coactivator SRC-1 is an essential coordinator of hepatic glucose production.

NCOA3 NCOA1

1.87e-06248221109193
Pubmed

Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor.

NCOA3 NCOA1

1.87e-06248216141356
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

1.87e-06248229217654
Pubmed

Immunohistochemical localization of steroid receptor coactivators in chondrosarcoma: an in vivo tissue microarray study.

NCOA3 NCOA1

1.87e-06248224875297
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

1.87e-06248220717166
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

1.87e-06248210049825
Pubmed

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration.

BCL9L BCL9

1.87e-06248238811552
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

1.87e-06248227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

1.87e-06248229170789
InteractionTBXT interactions

NCOA3 NCOA6 ZNF536 ARID1B KMT2D CAD MED8 CHD7 BCL9 SS18 CREBBP EP300

3.26e-171164712int:TBXT
InteractionSP7 interactions

BCL9L NCOA3 NCOA6 ZNF536 ARID1B KMT2D CAD RBM12 NCOA1 CHD7 BCL9 SS18 CREBBP EP300

5.12e-153044714int:SP7
InteractionEGR2 interactions

BCL9L NCOA3 NCOA6 ZNF536 ARID1B KMT2D NCOA1 CHD7 BCL9 CREBBP EP300

1.59e-131714711int:EGR2
InteractionHNF4A interactions

FOXO1 NCOA3 NCOA6 ARID1B GTF2H1 KMT2D MED8 NCOA1 CHD7 SS18 CREBBP EP300

1.12e-122754712int:HNF4A
InteractionGCM1 interactions

NCOA3 ZNF536 ARID1B KMT2D BCL9 SS18 CREBBP EP300

3.11e-1268478int:GCM1
InteractionCRX interactions

BCL9L NCOA3 ZNF536 ARID1B KMT2D NCOA1 MLLT6 CHD7 BCL9 CREBBP EP300

1.20e-112544711int:CRX
InteractionGATA3 interactions

NCOA3 ZNF536 ARID1B KMT2D RBM12 MLLT6 CHD7 BCL9 CREBBP EP300

1.43e-111874710int:GATA3
InteractionPAX9 interactions

BCL9L NCOA3 NCOA6 ZNF536 ARID1B KMT2D CHD7 BCL9 EP300

1.62e-11130479int:PAX9
InteractionMYOD1 interactions

NCOA3 ARID1B KMT2D TCF12 MED8 NCOA1 BCL9 SS18 CREBBP EP300

2.06e-111944710int:MYOD1
InteractionGSC interactions

BCL9L NCOA3 ZNF536 ARID1B KMT2D BCL9 CREBBP EP300

2.38e-1187478int:GSC
InteractionGATA2 interactions

NCOA3 NCOA6 ZNF536 ARID1B KMT2D CHD7 BCL9 SS18 CREBBP EP300

2.65e-111994710int:GATA2
InteractionSOX9 interactions

NCOA3 NCOA6 ARID1B KMT2D CHD7 BCL9 CREBBP EP300

5.78e-1197478int:SOX9
InteractionERG interactions

NCOA3 NCOA6 ARID1B KMT2D CAD CHD7 BCL9 SS18 CREBBP EP300

8.14e-112234710int:ERG
InteractionPPARG interactions

FOXO1 NCOA3 NCOA6 ZNF536 ARID1B KMT2D NCOA1 MLLT6 IKBKB CREBBP EP300

9.17e-113074711int:PPARG
InteractionFOS interactions

NCOA3 NCOA6 ARID1B KMT2D TCF12 MED8 NCOA1 BCL9 SS18 CREBBP EP300

1.09e-103124711int:FOS
InteractionTBR1 interactions

BCL9L NCOA3 ZNF536 ARID1B KMT2D CHD7 BCL9 EP300

1.99e-10113478int:TBR1
InteractionETV4 interactions

NCOA3 ARID1B KMT2D BCL9 SS18 CREBBP EP300

2.28e-1069477int:ETV4
InteractionPAX7 interactions

NCOA3 ARID1B KMT2D CHD7 BCL9 SS18 CREBBP EP300

4.21e-10124478int:PAX7
InteractionHNF1B interactions

NCOA3 ZNF536 ARID1B KMT2D MLLT6 CHD7 BCL9 CREBBP EP300

4.87e-10190479int:HNF1B
InteractionSOX7 interactions

NCOA3 ARID1B KMT2D NCOA1 CHD7 CREBBP EP300

7.84e-1082477int:SOX7
InteractionTLE3 interactions

BCL9L NCOA3 ARID1B KMT2D RBM12 TCF12 NCOA1 MLLT6 BCL9 CREBBP EP300

7.87e-103764711int:TLE3
InteractionSOX10 interactions

NCOA3 ARID1B KMT2D TCF12 CHD7 BCL9 EP300

1.78e-0992477int:SOX10
InteractionFOXI1 interactions

NCOA3 ZNF536 ARID1B KMT2D BCL9 CREBBP EP300

1.78e-0992477int:FOXI1
InteractionSOX17 interactions

NCOA3 NCOA6 ARID1B KMT2D CHD7 BCL9 SS18

2.23e-0995477int:SOX17
InteractionSMG7 interactions

NCOA3 NCOA6 ARID1B KMT2D RBM12 NCOA1 MLLT6 BCL9 CREBBP CNOT2

2.64e-093194710int:SMG7
InteractionNUP35 interactions

BCL9L NCOA3 NCOA6 ARID1B KMT2D RBM12 NUP155 BCL9 CREBBP CNOT2 EP300

2.77e-094244711int:NUP35
InteractionTLX1 interactions

NCOA3 ZNF536 ARID1B KMT2D CHD7 BCL9 CREBBP EP300

6.49e-09175478int:TLX1
InteractionPAX8 interactions

NCOA3 ARID1B KMT2D CHD7 BCL9 CREBBP EP300

6.66e-09111477int:PAX8
InteractionTEAD1 interactions

ZNF536 ARID1B KMT2D TCF12 NCOA1 CHD7 CREBBP EP300

6.79e-09176478int:TEAD1
InteractionPAX6 interactions

NCOA3 NCOA6 ZNF536 ARID1B KMT2D MLLT6 CHD7 BCL9 CREBBP EP300

9.84e-093664710int:PAX6
InteractionKLF5 interactions

NCOA3 NCOA6 ARID1B KMT2D BCL9 SS18 CREBBP EP300

1.51e-08195478int:KLF5
InteractionHOXB2 interactions

ARID1B KMT2D NCOA1 CREBBP EP300

1.98e-0836475int:HOXB2
InteractionTLX3 interactions

BCL9L NCOA3 NCOA6 ARID1B GTF2H1 KMT2D CHD7 BCL9 EP300

2.03e-08291479int:TLX3
InteractionFEV interactions

NCOA3 NCOA6 ARID1B KMT2D CHD7 BCL9 CREBBP EP300

2.07e-08203478int:FEV
InteractionAR interactions

FOXO1 BCL9L NCOA3 NCOA6 ARID1B GTF2H1 KMT2D RBM12 MED8 NCOA1 CHD7 BCL9 CREBBP EP300

3.33e-089924714int:AR
InteractionIRF4 interactions

NCOA3 ARID1B KMT2D CHD7 SS18 EP300

4.40e-0885476int:IRF4
InteractionCREBBP interactions

FOXO1 NCOA3 NCOA6 ARID1B KMT2D TCF12 NCOA1 MAML2 IKBKB CREBBP EP300

9.62e-085994711int:CREBBP
InteractionLHX2 interactions

BCL9L ZNF536 ARID1B KMT2D CHD7 BCL9 SS18

2.10e-07183477int:LHX2
InteractionNR3C1 interactions

NCOA3 NCOA6 ZNF536 ARID1B KMT2D SGTA MED8 NCOA1 CHD7 BCL9 SS18 CREBBP EP300

2.20e-079744713int:NR3C1
InteractionETS1 interactions

NCOA3 ARID1B KMT2D NCOA1 CREBBP EP300

3.63e-07121476int:ETS1
InteractionCEBPA interactions

NCOA3 NCOA6 ARID1B KMT2D CAD RBM12 TCF12 MED8 NCOA1 MLLT6 CHD7 BCL9 CREBBP EP300

5.46e-0712454714int:CEBPA
InteractionMYB interactions

ZNF536 KMT2D MLLT6 CHD7 CREBBP EP300

6.34e-07133476int:MYB
InteractionRARA interactions

FOXO1 NCOA3 NCOA6 TMOD1 NCOA1 CREBBP EP300

7.98e-07223477int:RARA
InteractionNCOA2 interactions

NCOA3 NCOA6 CAD NCOA1 CREBBP EP300

8.94e-07141476int:NCOA2
InteractionNCOA1 interactions

FOXO1 NCOA3 NCOA6 NCOA1 CREBBP EP300

1.10e-06146476int:NCOA1
InteractionELF5 interactions

ORC1 ARID1B KMT2D CHD7 SS18 EP300

1.14e-06147476int:ELF5
InteractionHNF1A interactions

NCOA3 KMT2D NCOA1 CREBBP EP300

1.17e-0680475int:HNF1A
InteractionPPARGC1A interactions

FOXO1 NCOA6 NCOA1 CREBBP EP300

1.32e-0682475int:PPARGC1A
InteractionEYA4 interactions

NCOA3 RBM12 NUP155 NCOA1 BCL9 CREBBP EP300

1.42e-06243477int:EYA4
InteractionSMARCC2 interactions

NCOA3 ARID1B GTF2H1 CAD CHD7 SS18 CREBBP EP300

1.42e-06353478int:SMARCC2
InteractionE2F5 interactions

ARID1B KMT2D CREBBP EP300

1.45e-0636474int:E2F5
InteractionPGR interactions

NCOA3 SGTA NCOA1 RBM23 EP300

1.49e-0684475int:PGR
InteractionPAX2 interactions

NCOA3 ARID1B KMT2D CHD7 BCL9

1.58e-0685475int:PAX2
InteractionASF1A interactions

NCOA6 ZNF536 ARID1B KMT2D MLLT6 CHD7 EP300

1.67e-06249477int:ASF1A
InteractionKLF4 interactions

NCOA3 ARID1B KMT2D BCL9 CREBBP EP300

1.87e-06160476int:KLF4
InteractionTFF1 interactions

NCOA3 CREBBP RBM23 EP300

2.47e-0641474int:TFF1
InteractionSMAD2 interactions

NCOA3 NCOA6 ARID1B CAD TCF12 TMOD1 CREBBP EP300

2.71e-06385478int:SMAD2
InteractionGATA1 interactions

ARID1B KMT2D RBM12 BCL9 CREBBP EP300

2.75e-06171476int:GATA1
InteractionEPAS1 interactions

ARID1B TCF12 MED8 IKBKB CREBBP EP300

2.94e-06173476int:EPAS1
InteractionALG13 interactions

NCOA3 ARID1B KMT2D RBM12 BCL9 EP300

4.07e-06183476int:ALG13
InteractionTHRB interactions

FOXO1 NCOA3 NCOA6 NCOA1 CHD7 EP300

4.47e-06186476int:THRB
InteractionPYGO2 interactions

BCL9L KMT2D BCL9 CREBBP

4.69e-0648474int:PYGO2
InteractionNR1I2 interactions

NCOA3 NCOA6 NCOA1 EP300

4.69e-0648474int:NR1I2
InteractionNFIA interactions

NCOA3 ARID1B KMT2D BCL9 CREBBP EP300

4.75e-06188476int:NFIA
InteractionTHRA interactions

NCOA3 NCOA6 NCOA1 CREBBP EP300

5.91e-06111475int:THRA
InteractionE2F1 interactions

NCOA3 NCOA6 ARID1B GTF2H1 CREBBP EP300

6.78e-06200476int:E2F1
InteractionMAML2 interactions

MAML2 CREBBP EP300

7.90e-0617473int:MAML2
InteractionTRIP4 interactions

CAD MED8 NCOA1 MLLT6 CREBBP EP300

8.03e-06206476int:TRIP4
InteractionSMAD3 interactions

FOXO1 NCOA3 NCOA6 ARID1B TCF12 NCOA1 CREBBP EP300

8.10e-06447478int:SMAD3
InteractionTPRX2 interactions

NCOA6 ARID1B KMT2D CREBBP

8.72e-0656474int:TPRX2
InteractionNR1H3 interactions

NCOA3 NCOA6 NCOA1 EP300

1.00e-0558474int:NR1H3
InteractionSMARCA4 interactions

FOXO1 ARID1B CAD NCOA1 CHD7 SS18 CREBBP EP300

1.03e-05462478int:SMARCA4
InteractionNEUROG1 interactions

TCF12 CREBBP EP300

1.12e-0519473int:NEUROG1
InteractionVDR interactions

NCOA3 NCOA6 NCOA1 CREBBP EP300

1.14e-05127475int:VDR
InteractionETS2 interactions

NCOA3 NCOA1 CREBBP EP300

1.23e-0561474int:ETS2
InteractionNCOA3 interactions

NCOA3 ARID1B NCOA1 IKBKB CREBBP EP300

1.29e-05224476int:NCOA3
InteractionSOX2 interactions

BCL9L NCOA3 NCOA6 ZNF536 CELSR1 ARID1B KMT2D TCF12 CHD7 BCL9 EFCAB7 SS18 EP300

1.48e-0514224713int:SOX2
InteractionRXRB interactions

CACNA1B NCOA3 GTF2H1 NCOA1

1.68e-0566474int:RXRB
InteractionSOX15 interactions

NCOA3 ARID1B KMT2D BCL9 EP300

1.89e-05141475int:SOX15
InteractionNFIB interactions

NCOA3 ARID1B KMT2D BCL9 CREBBP

1.96e-05142475int:NFIB
InteractionCITED2 interactions

IKBKB CREBBP EP300

2.04e-0523473int:CITED2
InteractionNCOA6 interactions

NCOA6 KMT2D NCOA1 CREBBP EP300

2.16e-05145475int:NCOA6
InteractionNR6A1 interactions

NCOA1 CREBBP EP300

2.32e-0524473int:NR6A1
InteractionTBP interactions

NCOA3 NCOA6 TCF12 NCOA1 CREBBP EP300

2.57e-05253476int:TBP
InteractionARNT interactions

FOXO1 CAD TCF12 NCOA1 CREBBP EP300

2.69e-05255476int:ARNT
InteractionSMARCC1 interactions

NCOA3 ARID1B NCOA1 CHD7 SS18 CREBBP EP300

2.82e-05384477int:SMARCC1
InteractionTP53BP1 interactions

NCOA3 NCOA6 ARID1B GTF2H1 TCF12 MED8 CREBBP EP300

2.88e-05533478int:TP53BP1
InteractionLHX4 interactions

BCL9L ARID1B KMT2D CHD7 BCL9

4.14e-05166475int:LHX4
InteractionIRF1 interactions

ARID1B SS18 CREBBP EP300

4.17e-0583474int:IRF1
InteractionARID1A interactions

ARID1B NCOA1 CHD7 SS18 CREBBP EP300

4.19e-05276476int:ARID1A
InteractionRXRA interactions

NCOA3 NCOA6 NCOA1 CREBBP EP300

4.51e-05169475int:RXRA
InteractionKMT2D interactions

NCOA6 KMT2D NUP155 CREBBP EP300

4.51e-05169475int:KMT2D
InteractionTWIST1 interactions

TCF12 NUP155 CHD7 IKBKB EP300

4.64e-05170475int:TWIST1
InteractionSTAT6 interactions

NCOA3 NCOA1 CREBBP EP300

5.02e-0587474int:STAT6
InteractionSMARCE1 interactions

NCOA3 ARID1B NCOA1 CHD7 SS18 EP300

5.20e-05287476int:SMARCE1
InteractionDEFB131A interactions

RBM12 SGTA

5.30e-055472int:DEFB131A
InteractionKLF15 interactions

NCOA3 KMT2D NCOA1 BCL9 CREBBP EP300

5.51e-05290476int:KLF15
InteractionNEUROD1 interactions

TCF12 CREBBP EP300

5.62e-0532473int:NEUROD1
InteractionCACNB3 interactions

CACNA1B TMOD1 GEM

5.62e-0532473int:CACNB3
InteractionNR1H4 interactions

NCOA6 NCOA1 EP300

5.62e-0532473int:NR1H4
Cytoband9q22.3

ECM2 TMOD1

7.32e-05124929q22.3
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA3 NCOA1 CREBBP EP300

2.44e-0817344486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

5.15e-041834291
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 KMT2D

1.00e-0325342775
GeneFamilyBasic helix-loop-helix proteins

NCOA3 TCF12 NCOA1

1.14e-03110343420
GeneFamilyPHD finger proteins

KMT2D MLLT6

1.24e-029034288
CoexpressionGRESHOCK_CANCER_COPY_NUMBER_UP

FOXO1 TCF12 MLLT6 MAML2 BCL9 SS18 CREBBP EP300

1.20e-07323488M9150
CoexpressionGSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN

NCOA6 VPS13D KMT2D SGTA IKBKB HERPUD2

1.72e-06200486M4876
CoexpressionGSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP

KMT2D ECM2 NCOA1 CHD7 GEM

3.15e-05199485M8105
CoexpressionREN_ALVEOLAR_RHABDOMYOSARCOMA_UP

ZNF536 TMOD1 NCOA1 CHD7

3.28e-0599484M768
CoexpressionAtlasalpha beta T cells, T.4Nve.MLN, 4+ 8- 25- 62Lhi 44lo, Lymph Node, avg-3

FOXO1 BCL9L CELSR1 KMT2D MLLT6 CHD7 MAML2

1.15e-05344487GSM538377_500
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FOXO1 ZNF536 DACH2 ABCA6 TMOD1

2.49e-061974956d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOXO1 ZNF536 DACH2 TMOD1

2.36e-05152494621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOXO1 ZNF536 TMOD1 GEM

2.42e-051534941524557514668f515ac1bbe847611f564b265b42
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOXO1 DACH2 ANKRD61 TMOD1

3.33e-0516649494636dbc039f794c735960c3425e00bdd5523602
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXO1 ZNF536 DACH2 MAML2

4.09e-051754941799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF536 DACH2 TMOD1 GEM

4.27e-05177494b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 CHD7 MAML2 MYRF

4.97e-05184494a2191dd5546efd357b23e625beb3c5820476f243
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 ANGPT4 PZP GEM

5.07e-05185494e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZNF536 DACH2 TMOD1 GEM

5.07e-05185494e58a009aaf342be019a909747b1895d5987d4daf
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 ANGPT4 PZP GEM

5.18e-051864946add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 CHD7 MAML2 MYRF

5.29e-0518749497e520705491c8f52a32025311a9fa7b9176979a
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ZNF536 DACH2 ABCA6 ECM2

5.29e-05187494bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 CHD7 MAML2 MYRF

5.40e-05188494b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 CHD7 MAML2 MYRF

5.40e-05188494505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXO1 ZNF536 RGS9 CNOT2

5.40e-051884946468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXO1 ZNF536 RGS9 CNOT2

5.40e-051884947a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXO1 ZNF536 RGS9 CNOT2

5.40e-051884949cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 ANGPT4 PZP GEM

5.51e-051894947ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ZNF536 DACH2 TMOD1 GEM

5.63e-05190494645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 CHD7 MAML2 MYRF

5.63e-051904942de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellControl-Lymphoid_B-B_intermediate|Control / Disease group, lineage and cell class

NCOA3 CELSR1 ABCA6 CHD7

5.74e-051914940082181dbc39c7c4fd3aa34c3ed61439548e844b
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 CHD7 MAML2 MYRF

5.74e-051914942b056cbe2e82e056e1f798974999378460eb1d16
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 CHD7 MAML2 MYRF

5.74e-05191494f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 CHD7 MAML2 MYRF

5.74e-05191494a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 ARID1B TCF12 MAML2

5.86e-05192494e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FOXO1 ARID1B TCF12 MAML2

5.98e-05193494779276e775cb2492e8dd36436295a536084a6415
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

ZNF536 DACH2 ABCA6 GEM

5.98e-05193494e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellIPF-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

ECM2 TMOD1 MYRF GEM

6.10e-05194494d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

FOXO1 ABCA6 NCOA1 MAML2

6.22e-05195494ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

FOXO1 ARID1B ABCA6 MAML2

6.22e-051954946a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B TCF12 NCOA1 MAML2

6.35e-05196494ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

FOXO1 ARID1B ABCA6 MAML2

6.35e-05196494e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BCL9L MLLT6 RGS9 PZP

6.60e-05198494a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B TCF12 NCOA1 MAML2

6.60e-051984941996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

BCL9L MLLT6 RGS9 PZP

6.60e-05198494a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BCL9L MLLT6 RGS9 PZP

6.60e-0519849476aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BCL9L MLLT6 RGS9 PZP

6.60e-05198494df399674345c45738d765a8354ea8d1484572c34
ToppCellCOVID-19_Mild-Lymphoid_T/NK-gd_T|COVID-19_Mild / Disease group, lineage and cell class

BCL9L MLLT6 RGS9 PZP

6.60e-051984946aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 SCAMP5 TMOD1 MYRF

6.73e-0519949467d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B TCF12 NCOA1 MAML2

6.73e-0519949494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellControl-Control-Lymphocyte-B-B_intermediate|Control / Disease, condition lineage and cell class

NCOA3 CELSR1 ABCA6 CHD7

6.73e-05199494ee6f07eec7edfe41d2f7fcb0b509ce00e99a6a95
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T|COVID-19_Mild / Disease, condition lineage and cell class

BCL9L MLLT6 RGS9 PZP

6.86e-052004946560753d3df2f87860b52052d4881aa45410f666
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-ADAMTSL1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF536 DACH2 CHD7 MAML2

6.86e-05200494e1fca7ee2dc18c7fded53c3561f519c1fcd9767a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 SCAMP5 TMOD1 MYRF

6.86e-052004940e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BCL9L MLLT6 RGS9 PZP

6.86e-05200494d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

FOXO1 CHD7 MAML2 MYRF

6.86e-05200494e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-ADAMTSL1-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF536 DACH2 CHD7 MAML2

6.86e-052004944409471479dd7c0f770bcb84ba7b3652c4706743
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BCL9L MLLT6 RGS9 PZP

6.86e-05200494109f673a4967ffa52270a0b4f818b3461288db44
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ANGPT4 ANKRD61 MYRF

2.48e-04111493bb59f1909645fd512f0ea806e5593d4a1c6e25d9
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

ABCA6 ANGPT4 MYRF

2.75e-0411549315b2c11225802cc15c01165d84a755432f02d82f
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Striatum / BrainAtlas - Mouse McCarroll V32

ZNF536 DACH2 CPS1

4.21e-04133493d5326a6ccada5ae6d3e8f7d4a858c90050e23c5b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

VPS13D ANGPT4 RGS9

4.31e-041344932647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 SCAMP5 BCL9

5.10e-041424935690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_small-bowel / Manually curated celltypes from each tissue

ABCA6 RGS9 PZP

5.31e-04144493a4bb274d553c29c8299354de757ecc5634008c68
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CELSR1 ECM2 RGS9

5.53e-041464935b2608b56204dda9a773988f42ff00a9fa743a39
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FOXO1 ZNF536 CPS1

6.21e-041524938ff5a178a8f3550d89a003c0858820aab3773386
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF536 TMOD1 GEM

6.58e-04155493cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 CPS1 PZP

6.70e-04156493e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CACNA1B ZNF536 DACH2

6.83e-04157493b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2H1 NUP155 MAML2

6.95e-041584931d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

KMT2D BCL9 EP300

7.08e-04159493037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZNF536 DACH2 RGS9

7.21e-041604935cd4fbbd2ce671a8377416eff94041a111375dee
ToppCellCD8+_Memory_T_cell-FLU-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MAML2 PZP MYRF

7.48e-0416249376f39935763848ea6e7917b2f9f1432c543063d9
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ORC1 CPS1 MYRF

7.48e-04162493768a566e76923323c1f197f60bab472a8784490b
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ORC1 SLC15A1 TMOD1

7.75e-04164493cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ORC1 SLC15A1 TMOD1

7.75e-041644935dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

ZNF536 ABCA6 ECM2

7.75e-041644933d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ORC1 SLC15A1 TMOD1

7.75e-04164493f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCellfacs-Trachea-nan-18m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ORC1 SLC15A1 TMOD1

7.88e-041654937e7643834ed483aec04f513cca38d6367fda9ff8
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

FOXO1 ZNF536 ABCA6

7.88e-041654936ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NCOA6 MROH1 MYRF

8.02e-04166493dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOM1L1 TMOD1 MYRF

8.16e-041674939f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

ZNF536 ABCA6 GEM

8.16e-04167493d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOM1L1 TMOD1 MYRF

8.16e-04167493bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

FOXO1 ZNF536 ABCA6

8.31e-0416849388c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

FOXO1 ZNF536 ABCA6

8.45e-04169493a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

FOXO1 ABCA6 MAML2

8.45e-041694936373562ab3b1765060212a6a53d6543e7e942e80
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1B DACH2 SLC15A1

8.45e-04169493b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NUP155 CHD7 RBM23

8.74e-04171493bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ORC1 MED8 EFCAB7

8.89e-04172493fe3d0d8cb5f613ac2cfff450599698f1533a354f
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF536 DACH2 TMOD1

9.04e-041734931f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 DACH2 CHD7

9.19e-04174493fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 DACH2 CHD7

9.19e-041744938d8cf8ad17dcc364f867e36b10834a21c0e36ad2
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 ABCA6 MAML2

9.19e-04174493f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

CACNA1B DACH2 SATL1

9.34e-041754934db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF12 RGS9 MAML2

9.34e-041754938a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

CACNA1B DACH2 SATL1

9.34e-041754938d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZNF536 CELSR1 BCL9

9.50e-04176493792f414f5092aba14260b8e16378e793a822498e
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZNF536 KMT2D CHD7

9.66e-041774935357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 ABCA6 ECM2

9.66e-041774939ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 ABCA6 ECM2

9.66e-04177493016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 ECM2 GEM

9.81e-0417849309475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 ECM2 GEM

9.81e-0417849335de8f791b0e78a6caf52ff095f05e204a59e828
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ZNF536 MAML2

9.81e-0417849308b4a497aca0aeabf4f6a8a55c05b56417b69e78
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF12 RGS9 MAML2

9.81e-04178493a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 ECM2 GEM

9.81e-04178493000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOM1L1 TMOD1 MYRF

9.97e-0417949388dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOM1L1 TMOD1 MYRF

9.97e-04179493daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 DACH2 TMOD1

9.97e-041794937394e77e665bf16d3733df91bb12907be460ab44
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

FOXO1 ABCA6 MAML2

9.97e-04179493dcb6ec9ae72b13fe388b72dace2815293fafe8ee
Drugglutamin

FOXO1 NCOA3 CAD SGTA NCOA1 CPS1 CREBBP EP300

4.93e-06461488CID000000738
DrugAC1Q68Z5

ORC1 NCOA3 GTF2H1 NCOA1 CPS1 CREBBP EP300

1.54e-05386487CID000000181
DrugPhe-gly

NUP155 SLC15A1 CREBBP EP300

1.70e-0573484CID000098207
DiseaseDiffuse Large B-Cell Lymphoma

FOXO1 KMT2D CREBBP EP300

1.82e-0655474C0079744
DiseaseMenke-Hennekam syndrome

CREBBP EP300

2.48e-062472cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

2.48e-062472DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

2.48e-062472cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

2.48e-062472C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

2.48e-062472180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

2.48e-062472cv:C4551859
Diseasecarbamoyl phosphate synthetase I deficiency disease (implicated_via_orthology)

CAD CPS1

2.48e-062472DOID:9280 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

2.48e-062472DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

2.48e-062472C0035934
Diseasebreast carcinoma (is_marker_for)

NCOA3 KMT2D NCOA1 EP300

3.79e-0666474DOID:3459 (is_marker_for)
Diseaseprostate cancer (is_marker_for)

FOXO1 NCOA3 KMT2D NCOA1 EP300

4.97e-06156475DOID:10283 (is_marker_for)
DiseaseProstatic Neoplasms

FOXO1 NCOA3 KMT2D TOM1L1 TMOD1 NCOA1 CHD7 CREBBP

5.29e-06616478C0033578
DiseaseMalignant neoplasm of prostate

FOXO1 NCOA3 KMT2D TOM1L1 TMOD1 NCOA1 CHD7 CREBBP

5.29e-06616478C0376358
DiseaseCongenital small ears

ORC1 KMT2D CHD7

3.87e-0541473C0152423
Diseaseautism spectrum disorder (implicated_via_orthology)

ARID1B SCAMP5 CHD7 CREBBP

1.02e-04152474DOID:0060041 (implicated_via_orthology)
DiseaseMicrophthalmos

KMT2D MYRF

1.35e-0411472C0026010
DiseaseLymphoma, Large-Cell, Follicular

KMT2D CREBBP

2.57e-0415472C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

KMT2D CREBBP

2.57e-0415472C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

KMT2D CREBBP

2.57e-0415472C0079758
DiseaseLymphoma, Follicular, Grade 2

KMT2D CREBBP

2.57e-0415472C1956132
DiseaseLymphoma, Follicular, Grade 3

KMT2D CREBBP

2.57e-0415472C1956131
DiseaseLymphoma, Follicular, Grade 1

KMT2D CREBBP

2.57e-0415472C1956130
Diseasealcohol use disorder (implicated_via_orthology)

ARID1B ANGPT4 CREBBP EP300

2.64e-04195474DOID:1574 (implicated_via_orthology)
DiseaseT-Cell Lymphoma

KMT2D EP300

2.94e-0416472C0079772
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

NCOA3 MAML2

4.17e-0419472EFO_0000220, GO_0097327
Diseaseserum homoarginine measurement

SLC15A1 CPS1

4.63e-0420472EFO_0005421
DiseaseLymphoma, Follicular

KMT2D CREBBP

4.63e-0420472C0024301
Diseasecorneal hysteresis

FOXO1 ABCA6

4.63e-0420472EFO_0010066
Diseasehypertension (biomarker_via_orthology)

ARID1B CPS1 IKBKB EP300

4.69e-04227474DOID:10763 (biomarker_via_orthology)
DiseaseSquamous cell carcinoma of esophagus

KMT2D CREBBP EP300

4.73e-0495473C0279626
Diseasesphingomyelin 24:1 measurement

CELSR1 DACH2

6.15e-0423472EFO_0010398
Diseasesevere acute respiratory syndrome, COVID-19

DACH2 SLC15A1 SHOX MAML2 EFCAB7

7.09e-04447475EFO_0000694, MONDO_0100096
Diseasetotal blood protein measurement

NCOA3 KMT2D ABCA6 MAML2 CPS1

7.23e-04449475EFO_0004536
Diseaselipoprotein A measurement

ARID1B ABCA6 CPS1

7.64e-04112473EFO_0006925
DiseaseSezary Syndrome

KMT2D CREBBP

8.50e-0427472C0036920
DiseaseSquamous cell carcinoma

NCOA3 CREBBP EP300

1.03e-03124473C0007137
DiseaseLymphoma, Non-Hodgkin

IKBKB CREBBP

1.19e-0332472C0024305
DiseaseBladder Neoplasm

KMT2D CREBBP EP300

1.45e-03140473C0005695
DiseaseMalignant neoplasm of breast

NCOA3 NCOA6 ARID1B KMT2D NCOA1 IKBKB EP300

1.46e-031074477C0006142
DiseaseMalignant neoplasm of urinary bladder

KMT2D CREBBP EP300

1.48e-03141473C0005684

Protein segments in the cluster

PeptideGeneStartEntry
RLQKQNMLPNAAGMV

EP300

651

Q09472
QNMNPMQAGVQRAGL

EP300

2131

Q09472
QRLQMAGGSQLPMAS

MLLT6

981

P55198
MRNVQFPGMAPQNLG

ABCA6

51

Q8N139
QQMRTLNPLGNNPMN

CREBBP

516

Q92793
PVNRMQVSQGMNSFN

CREBBP

711

Q92793
MGGLNPQGQALNIMN

CREBBP

2161

Q92793
QQHLPLQGSSMGQMA

CREBBP

2251

Q92793
GAMSNLGMGQRQQFP

ARID1B

1386

Q8NFD5
LRMTNNQGILPAGIM

ANKRD61

341

A6NGH8
MGGTPTNVATLNMNN

CELSR1

1846

Q9NYQ6
LMAMNTLQGNGSQNG

DACH2

231

Q96NX9
RDQMQQAPGGLSQMG

CACNA1B

1871

Q00975
TGMNQNLGLTNNTPM

CHD7

326

Q9P2D1
GSGAPMNLNNNLNPM

RBM12

261

Q9NTZ6
MANNLQKGNGGPMRL

RBM23

251

Q86U06
LGSAMQNIQNLLQMP

PZP

961

P20742
DMQNPETGVRMQNQR

RGS9

26

O75916
VTMRQGTVGMQPQQQ

GEM

6

P55040
MNASRLSQPGQLMSQ

IKBKB

676

O14920
MNPQQQRMAAIGTDK

TCF12

1

Q99081
SLLQRNMTPQGLQIM

MROH1

906

Q8NDA8
IGFMRPENGNPQQMQ

NUP155

746

O75694
INNGQSQIMSGTLPM

MAML2

221

Q8IZL2
LLQQMQNQPIAGMGY

MAML2

691

Q8IZL2
QMSQTLNGQTMGPLR

MAML2

1031

Q8IZL2
QNRSQDVRMNGPMGA

NCOA6

141

Q14686
QPSLMGIHGNMNNQQ

NCOA6

581

Q14686
QNQSNVMPGPAQIMR

NCOA6

731

Q14686
VQFTGQMSGQMLPQQ

NCOA6

756

Q14686
QMSGQMLPQQGPVNN

NCOA6

761

Q14686
RLELGNLGNPQMSQQ

ORC1

236

Q13415
MSMANRGQNQPVLNI

CPS1

311

P31327
QPNSRVLGQNVMMGP

FOXO1

486

Q12778
MGANGNRNSKLMEPN

EFCAB7

251

A8K855
VNQLGNMQNMRLGPS

LINC02876

36

F2Z3M2
NNMPGMGINTQNPRI

BCL9

1051

O00512
NQIQRVPGFGGMQSM

BCL9L

606

Q86UU0
NLPGQQGVQRGLNMS

BCL9L

1376

Q86UU0
QQMAQNQTAPMLELG

ANGPT4

121

Q9Y264
MRLNMDGNNLIQIPS

ECM2

396

O94769
RPMNENVQMNAQGGP

HERPUD2

251

Q9BSE4
NIGNNTMNISLPGEM

SLC15A1

401

P46059
NAAMGAAQGAMNQPQ

SCAMP5

206

Q8TAC9
QQQPMLSGVQMAQAG

MED8

231

Q96G25
MPRATLGELNTMNNQ

TOM1L1

326

O75674
PQIQQLMSGMISGGN

SGTA

241

O43765
VGINMRSGMQQQITP

NCOA1

1086

Q15788
QMNQQGNFPLQGMHP

NCOA3

1141

Q9Y6Q9
QIGTNQSGMSQPVMQ

SATL1

126

Q86VE3
MSQQVPSQLGMRQPG

SATL1

446

Q86VE3
NMGALRMPFQQVQAQ

SHOX

201

O15266
MRGMSNNTPQLNRSL

CNOT2

86

Q9NZN8
MQGGTQQAINQMVPN

GTF2H1

441

P32780
QQGPRLRASNAMMNN

TMOD1

321

P28289
QNQMTMSQGQPMGNY

SS18

176

Q15532
GGQLPNNMAMALHRQ

CAD

1016

P27708
PMGSQMALLANQLGR

ZNF536

76

O15090
EQQFINQKMRPGSGM

VPS13D

3761

Q5THJ4
GSMTQNLLGPQQPML

KMT2D

4146

O14686
LNAQMLNGMIKQEPG

MYRF

266

Q9Y2G1