Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondamaged DNA binding

XPA MSH6 FEN1 NEIL3 RPA1

8.11e-05841055GO:0003684
GeneOntologyMolecularFunctionATP-dependent activity

KIF18A MYO1A DNAH10 ABCC9 CCT7 KIF20B MSH6 ACSM4 DNAH12 MACF1 ABCG2 ATP12A

9.25e-0561410512GO:0140657
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF18A MYO1A DNAH10 KIF20B DNAH12

3.99e-041181055GO:0003774
GeneOntologyMolecularFunctioncadherin binding

PKP4 CKAP5 EPS15L1 FASN MB21D2 P2RX4 PKP1 MACF1

4.25e-043391058GO:0045296
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF18A DNAH10 KIF20B DNAH12

5.07e-04701054GO:0003777
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF18A DNAH10 ABCC9 CCT7 KIF20B DNAH12 MACF1 ABCG2 ATP12A

5.33e-044411059GO:0016887
GeneOntologyMolecularFunctionmanganese ion binding

ADCY2 B4GALT1 FEN1 PRIMPOL

5.35e-04711054GO:0030145
GeneOntologyCellularComponentdesmosome

PKP4 B4GALT1 PKP1

3.68e-04281053GO:0030057
GeneOntologyCellularComponentreplication fork

XPA MCM10 RPA1 PRIMPOL

6.14e-04771054GO:0005657
GeneOntologyCellularComponenthigh-density lipoprotein particle

APOB LCAT APOL2

7.17e-04351053GO:0034364
GeneOntologyCellularComponentsupramolecular fiber

GLYAT KIF18A DPYSL3 MYO1A DNAH10 CKAP5 ABCC9 CCT7 KIF20B MYLK2 DNAH12 PKP1 FMN2 MACF1 AHNAK2

7.97e-04117910515GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

GLYAT KIF18A DPYSL3 MYO1A DNAH10 CKAP5 ABCC9 CCT7 KIF20B MYLK2 DNAH12 PKP1 FMN2 MACF1 AHNAK2

8.54e-04118710515GO:0099081
GeneOntologyCellularComponentspindle midzone

KIF18A PKP4 KIF20B

1.06e-03401053GO:0051233
GeneOntologyCellularComponentinner dynein arm

DNAH10 DNAH12

1.10e-03101052GO:0036156
GeneOntologyCellularComponentnuclear replication fork

XPA MCM10 RPA1

1.23e-03421053GO:0043596
GeneOntologyCellularComponentlipoprotein particle

APOB LCAT APOL2

1.40e-03441053GO:1990777
GeneOntologyCellularComponentplasma lipoprotein particle

APOB LCAT APOL2

1.40e-03441053GO:0034358
DomainVDCC_a2/dsu

CACNA2D1 CACNA2D2

1.90e-0441062IPR013680
DomainVGCC_alpha2

CACNA2D1 CACNA2D2

1.90e-0441062PF08473
DomainDCN-prot

DCUN1D1 DCUN1D2

3.16e-0451062IPR014764
DomainAWS

NSD1 SETD2

3.16e-0451062SM00570
DomainVWA_N

CACNA2D1 CACNA2D2

3.16e-0451062IPR013608
DomainPONY_dom

DCUN1D1 DCUN1D2

3.16e-0451062IPR005176
DomainVWA_N

CACNA2D1 CACNA2D2

3.16e-0451062PF08399
DomainAWS

NSD1 SETD2

3.16e-0451062PS51215
DomainDCUN1

DCUN1D1 DCUN1D2

3.16e-0451062PS51229
DomainAWS_dom

NSD1 SETD2

3.16e-0451062IPR006560
DomainCullin_binding

DCUN1D1 DCUN1D2

3.16e-0451062PF03556
DomainPlakophilin/d_Catenin

PKP4 PKP1

6.58e-0471062IPR028435
DomainARM-type_fold

DOCK2 PKP4 CKAP5 APOB HEATR1 ARMCX2 MROH7 PKP1

6.99e-043391068IPR016024
DomainARM-like

DOCK2 PKP4 CKAP5 HEATR1 ARMCX2 MROH7 PKP1

8.81e-042701067IPR011989
Domain-

ACAT1 FASN

1.39e-031010623.40.47.10
DomainThiolase-like

ACAT1 FASN

1.39e-03101062IPR016039
DomainARM_REPEAT

PKP4 ARMCX2 PKP1

1.51e-03401063PS50176
DomainARM

PKP4 ARMCX2 PKP1

1.51e-03401063SM00185
Domain-

PKP4 CKAP5 HEATR1 ARMCX2 MROH7 PKP1

1.67e-0322210661.25.10.10
DomainArmadillo

PKP4 ARMCX2 PKP1

2.40e-03471063IPR000225
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH12

2.78e-03141062IPR024317
DomainDynein_heavy_dom-2

DNAH10 DNAH12

2.78e-03141062IPR013602
DomainDHC_N2

DNAH10 DNAH12

2.78e-03141062PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH12

2.78e-03141062IPR011704
DomainAAA_8

DNAH10 DNAH12

2.78e-03141062PF12780
DomainAAA_5

DNAH10 DNAH12

2.78e-03141062PF07728
DomainDHC_fam

DNAH10 DNAH12

3.19e-03151062IPR026983
DomainDynein_heavy

DNAH10 DNAH12

3.19e-03151062PF03028
DomainDynein_heavy_dom

DNAH10 DNAH12

3.19e-03151062IPR004273
DomainPost-SET_dom

NSD1 SETD2

3.64e-03161062IPR003616
DomainPostSET

NSD1 SETD2

3.64e-03161062SM00508
DomainPOST_SET

NSD1 SETD2

3.64e-03161062PS50868
DomainVWC_out

NELL1 FCGBP

5.12e-03191062SM00215
DomainPWWP

NSD1 MSH6

5.67e-03201062SM00293
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

UBR1 RTCB MYCBP2 ACAT1 PKP4 CKAP5 ATL3 CCT7 HEATR1 MCM10 KIF20B POLR1F MSH6 NAA35 FASN FEN1 PKP1 MACF1 RPA1 AHNAK2

5.22e-0913531072029467282
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

KIF18A SLF1 NSD1 MCM10 ARMCX2 JMJD1C KIF20B SETD2 FAM111A BOD1L1 RPA1

1.64e-074531071129656893
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

DPYSL3 RTCB MYCBP2 NSD1 HEATR1 JMJD1C MSH6 SETD2 EPS15L1 FASN BOD1L1

1.09e-065491071138280479
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DPYSL3 RTCB CKAP5 CCT7 HEATR1 MSH6 SETD2 EPS15L1 FASN FEN1 MACF1 BOD1L1 RPA1 AHNAK2

1.11e-069341071433916271
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

CKAP5 HEATR1 MCM10 KIF20B MSH6 FASN FEN1 PPIE RPA1

2.27e-06370107922922362
Pubmed

Impact of genetic polymorphisms on platelet function and aspirin resistance.

APOB F5 MTHFR

2.35e-069107319923980
Pubmed

Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase.

RTCB CCT7 FEN1 RPA1

2.85e-0632107423277564
Pubmed

Defining the membrane proteome of NK cells.

DOCK2 ABR MYCBP2 CKAP5 ATL3 HEATR1 F5 B4GALT1 EPS15L1 FASN P2RX4 FEN1 KDSR APOL2 ACAP2

2.99e-0611681071519946888
Pubmed

A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss.

APOB F5 MTHFR

3.34e-0610107319906129
Pubmed

Prevalence of prothrombotic polymorphisms in Greece.

APOB F5 MTHFR

3.34e-0610107319072566
Pubmed

Genetic polymorphisms associated with thrombophilia and vascular disease in women with unexplained late intrauterine fetal death: a multicenter study.

APOB F5 MTHFR

3.34e-0610107314706682
Pubmed

Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients.

APOB F5 MTHFR

3.34e-0610107320425806
Pubmed

A comprehensive analysis of 12 thrombophilic mutations and related parameters in patients with inflammatory bowel disease: data from Turkey.

APOB F5 MTHFR

3.34e-0610107317111197
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

KIF18A PPAN RTCB MYCBP2 CKAP5 HEATR1 MCM10 KIF20B POLR1F MSH6 MB21D2 MACF1

4.00e-067591071235915203
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

EFCAB5 RTCB MYCBP2 ACAT1 CKAP5 CCT7 KIF20B MSH6 FASN FEN1 BOD1L1 RPA1

7.61e-068091071232129710
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SLF1 RTCB ACAT1 NSD1 HEATR1 SS18 JMJD1C KIF20B POLR1F SETD2 EPS15L1 FEN1 BOD1L1

7.71e-069541071336373674
Pubmed

Genetic influences on blood pressure within the Stanislas Cohort.

APOB F5 MTHFR

7.92e-0613107315076187
Pubmed

Genetic cardiovascular risk factors and age-related macular degeneration.

APOB F5 MTHFR

7.92e-0613107319860767
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

CKAP5 NSD1 LARS2 SS18 FASN MACF1 APOL2 AHNAK2

9.10e-06332107837433992
Pubmed

NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas.

NSD1 SETD2

9.38e-062107228754676
Pubmed

Hypercoagulable state in idiopathic ulcerative colitis: role of hyperhomocysteinemia and hyperfibrinogenemia.

F5 MTHFR

9.38e-062107218787277
Pubmed

The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis.

F5 MTHFR

9.38e-062107220935614
Pubmed

Expression levels of PEPT1 and ABCG2 play key roles in 5-aminolevulinic acid (ALA)-induced tumor-specific protoporphyrin IX (PpIX) accumulation in bladder cancer.

SLC15A1 ABCG2

9.38e-062107223993855
Pubmed

Expression and prognostic value of NSD1 and SETD2 in pancreatic ductal adenocarcinoma and its precursor lesions.

NSD1 SETD2

9.38e-062107231060750
Pubmed

Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.

F5 MTHFR

9.38e-062107216613994
Pubmed

Association of single nucleotide polymorphisms in MTHFR and ABCG2 with the different efficacy of first-line chemotherapy in metastatic colorectal cancer.

MTHFR ABCG2

9.38e-062107224338217
Pubmed

The Prevalence of Factor V Leiden (G1691A) and Methylenetetrahydrofolate Reductase C677T Mutations in Sickle Cell Disease in Western India.

F5 MTHFR

9.38e-062107223869056
Pubmed

No interaction between factor V Leiden and hyperhomocysteinemia or MTHFR 677TT genotype in venous thrombosis. Results of a meta-analysis of published studies and a large case-only study.

F5 MTHFR

9.38e-062107217200768
Pubmed

RPA and XPA interaction with DNA structures mimicking intermediates of the late stages in nucleotide excision repair.

XPA RPA1

9.38e-062107229320546
Pubmed

Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India.

F5 MTHFR

9.38e-062107223992124
Pubmed

Genetic thrombophilia in patients with VTE in eastern Mediterranean located tertiary care center; is it time to change the algorithm for thrombophilia work up decision making?

F5 MTHFR

9.38e-062107216683219
Pubmed

Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro.

SLC15A1 ABCG2

9.38e-062107222959800
Pubmed

Stroke in Young Military Men With Heterozygous for MTHFR Gene Mutation or Factor V Leiden Gene Mutation Associated With Patent Foramen Ovale: Report of Two Cases and Therapeutic Strategy.

F5 MTHFR

9.38e-062107233993312
Pubmed

Hereditary thrombophilic factors in stroke due to cerebral infarct.

F5 MTHFR

9.38e-062107219263510
Pubmed

Case-control Study of methylenetetrahydrofolate reductase mutations and hyperhomocysteinemia and risk of stroke.

F5 MTHFR

9.38e-062107219717029
Pubmed

Schizencephaly in infants with thrombophilia.

F5 MTHFR

9.38e-062107219168828
Pubmed

The association of factor V G1961A (factor V Leiden), prothrombin G20210A, MTHFR C677T and PAI-1 4G/5G polymorphisms with recurrent pregnancy loss in Bosnian women.

F5 MTHFR

9.38e-062107229703881
Pubmed

MTHFR C677T and factor V Leiden in recurrent pregnancy loss: a study among an endogamous group in North India.

F5 MTHFR

9.38e-062107219839754
Pubmed

MTHFR and F5 genetic variations have association with preeclampsia in Pakistani patients: a case control study.

F5 MTHFR

9.38e-062107231646966
Pubmed

Molecular basis for PrimPol recruitment to replication forks by RPA.

RPA1 PRIMPOL

9.38e-062107228534480
Pubmed

Methylenetetrahydrofolate reductase C677T polymorphism and Factor V Leiden variant in Mexican women with preeclampsia/eclampsia.

F5 MTHFR

9.38e-062107215905108
Pubmed

Combined germline variations of thrombophilic genes promote genesis of lung cancer.

F5 MTHFR

9.38e-062107224175756
Pubmed

Coexistence of left-sided inferior vena cava, deep vein thrombosis of the upper and lower extremities and prothrombotic polymorphisms in a young patient: a case report.

F5 MTHFR

9.38e-062107218600097
Pubmed

Primary habitual abortions are associated with high frequency of factor V Leiden mutation.

F5 MTHFR

9.38e-062107211056246
Pubmed

[Neonatal renal vein thrombosis in a heterozygous carrier of both factor V Leiden and the MTHFR gene mutation].

F5 MTHFR

9.38e-062107222361411
Pubmed

Impact of thrombophilic gene mutations on thrombosis risk in patients with gastrointestinal carcinoma.

F5 MTHFR

9.38e-062107212115343
Pubmed

MTHFR C677T Polymorphism and factor V Leiden mutation are not associated with recurrent spontaneous abortion of unexplained etiology in Japanese women.

F5 MTHFR

9.38e-062107216052395
Pubmed

Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions.

XPA RPA1

9.38e-062107211972036
Pubmed

A key interaction with RPA orients XPA in NER complexes.

XPA RPA1

9.38e-062107231925419
Pubmed

Amaurosis fugax: associations with heritable thrombophilia.

F5 MTHFR

9.38e-062107216015408
Pubmed

Incidence of and risk factors for childhood thrombosis: a single-center experience in Ankara, Turkey.

F5 MTHFR

9.38e-062107219206005
Pubmed

Pulmonary thromboembolism in childhood: a single-center experience from Turkey.

F5 MTHFR

9.38e-062107219150531
Pubmed

Maternal and fetal variants of genetic thrombophilias and the risk of preeclampsia.

F5 MTHFR

9.38e-062107215097012
Pubmed

Human PrimPol activity is enhanced by RPA.

RPA1 PRIMPOL

9.38e-062107228396594
Pubmed

The early-onset preeclampsia is associated with MTHFR and FVL polymorphisms.

F5 MTHFR

9.38e-062107225480409
Pubmed

Ethnic differences in the association of factor V Leiden mutation and the C677T methylenetetrahydrofolate reductase gene polymorphism with preeclampsia.

F5 MTHFR

9.38e-062107214746952
Pubmed

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation.

NSD1 SETD2

9.38e-062107218157086
Pubmed

Ethnic differences in the association of thrombophilic polymorphisms with obstetric complications in Slovak and Roma (Gypsy) populations.

F5 MTHFR

9.38e-062107225549181
Pubmed

The risk of venous thromboembolism associated with the factor V Leiden mutation and low B-vitamin status.

F5 MTHFR

9.38e-062107214580166
Pubmed

Recurrent abortions in Asian Indians: no role of factor V Leiden Hong Kong/Cambridge mutation and MTHFR polymorphism.

F5 MTHFR

9.38e-062107218160599
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ABR CKAP5 CCT7 AP3M1 JMJD1C EPS15L1 FASN MB21D2 MACF1 BOD1L1 RPA1

1.22e-057081071139231216
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

DPYSL3 MYCBP2 PKP4 EPS15L1 MB21D2 SH3PXD2A FMN2 MACF1

1.25e-05347107817114649
Pubmed

Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population.

APOB F5 MTHFR

1.25e-0515107311341749
Pubmed

Pharmacogenetic analyses of hematotoxicity in advanced gastric cancer patients receiving biweekly fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).

XPA MTHFR ABCG2

1.25e-0515107319074750
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK2 RTCB CKAP5 CCT7 MLKL MSH6 FASN FEN1 MACF1 RPA1

1.31e-055821071020467437
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CACNA2D1 PPAN RTCB MYCBP2 ACAT1 CKAP5 CCT7 HEATR1 F5 FASN PKP1 MACF1 RPA1

1.63e-0510241071324711643
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

DPYSL3 RTCB RBL1 CCT7 APOB HEATR1 POLR1F CASP12 SETD2 FASN ACAP2

2.17e-057541071135906200
Pubmed

Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.

APOB F5 FCGBP MTHFR ABCG2

2.17e-05108107519956635
Pubmed

Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance.

MSH6 FEN1 RPA1

2.65e-0519107334188037
Pubmed

Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3.

DPH1 ABR RPA1

2.65e-0519107312621583
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

DPYSL3 CCT7 KIF20B MSH6 FASN FEN1 FMN2 BOD1L1 PPIE

2.76e-05506107930890647
Pubmed

BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.

MCM10 PRIMPOL

2.81e-053107234645815
Pubmed

Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR G677A among 594 thrombotic Jordanian patients.

F5 MTHFR

2.81e-053107216093732
Pubmed

Factor V Leiden and increased risk for arterial thrombotic disease in young Brazilian patients.

F5 MTHFR

2.81e-053107216651869
Pubmed

The 19-bp deletion of dihydrofolate reductase (DHFR), methylenetetrahydrofolate reductase (MTHFR) C677T, Factor V Leiden, prothrombin G20210A polymorphisms in cancer patients with and without thrombosis.

F5 MTHFR

2.81e-053107218682947
Pubmed

[Association of hemostatic disorders in diabetic patients with methylenetetrahydrofolate reductase (C677T) and coagulation factors II (G20210A) and V (G1691A) gene polymorphism].

F5 MTHFR

2.81e-053107221574459
Pubmed

[The role of 1691G>A (Leiden) mutation in Factor V gene, 20210G>A in prothrombin gene and 677C>T in MTHFR gene in etiology of early pregnancy loss].

F5 MTHFR

2.81e-053107221853935
Pubmed

Prothrombin 20210A and oral contraceptive use as risk factors for cerebral venous thrombosis.

F5 MTHFR

2.81e-053107215528884
Pubmed

The role of thrombophilia and thyroid autoimmunity in unexplained infertility, implantation failure and recurrent spontaneous abortion.

F5 MTHFR

2.81e-053107218070829
Pubmed

Factor V Leiden, prothrombin 20210G>A, MTHFR 677C>T and 1298A>C, and homocysteinemia in Tunisian blood donors.

F5 MTHFR

2.81e-053107222628232
Pubmed

Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study. For the Childhood Thrombophilia Study Group.

F5 MTHFR

2.81e-053107211122096
Pubmed

Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester.

F5 MTHFR

2.81e-053107211506076
Pubmed

Thrombophilia in young patients with acute myocardial infarction.

F5 MTHFR

2.81e-053107218176672
Pubmed

[Prevalence of G20210A prothrombin gene mutation in Poland].

F5 MTHFR

2.81e-053107211434083
Pubmed

Thrombophilic risk factors and homocysteine levels in Behçet's disease in eastern Spain and their association with thrombotic events.

F5 MTHFR

2.81e-053107216601831
Pubmed

No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW.

MTHFR ABCG2

2.81e-053107223544272
Pubmed

Sequential binding of DNA repair proteins RPA and ERCC1 to XPA in vitro.

XPA RPA1

2.81e-05310728972858
Pubmed

MTHFR (C677T, A1298C), FV Leiden polymorphisms, and the prothrombin G20210A mutation in arterial ischemic stroke among young tunisian adults.

F5 MTHFR

2.81e-053107233400068
Pubmed

Paternal thrombophilic gene mutations are not associated with recurrent miscarriage.

F5 MTHFR

2.81e-053107218754836
Pubmed

Thrombophilic polymorphisms in Israel.

F5 MTHFR

2.81e-053107218583164
Pubmed

Inheritance and perinatal consequences of inherited thrombophilia in Greece.

F5 MTHFR

2.81e-053107217963764
Pubmed

Thrombosis Related ABO, F5, MTHFR, and FGG Gene Polymorphisms in Morbidly Obese Patients.

F5 MTHFR

2.81e-053107227999448
Pubmed

Thrombophilia-related genetic variations in patients with pulmonary embolism in the main teaching hospital in Jordan.

F5 MTHFR

2.81e-053107219618008
Pubmed

Association of allelic variants of factor V Leiden, prothrombin and methylenetetrahydrofolate reductase with thrombosis or ocular involvement in Behçet's disease: a systematic review and meta-analysis.

F5 MTHFR

2.81e-053107223207285
Pubmed

SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability.

SETD2 RPA1

2.81e-053107224931610
Pubmed

A retrospective study of the factors associated with hypercoagulability in the pediatric patients at a tertiary care children's hospital.

F5 MTHFR

2.81e-053107218679139
Pubmed

Inherited thrombophilia with recurrent pregnancy loss in Turkish women--a real phenomenon?

F5 MTHFR

2.81e-053107223342883
Pubmed

Portal vein thrombosis in children and adolescents: the low prevalence of hereditary thrombophilic disorders.

F5 MTHFR

2.81e-053107215359390
Pubmed

Rapid combined genotyping of factor V, prothrombin and methylenetetrahydrofolate reductase single nucleotide polymorphisms using minor groove binding DNA oligonucleotides (MGB probes) and real-time polymerase chain reaction.

F5 MTHFR

2.81e-053107215576297
Pubmed

A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis.

F5 MTHFR

2.81e-053107216082606
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PKP4 ARMCX2 PKP1

4.72e-0443643409
GeneFamilyDyneins, axonemal

DNAH10 DNAH12

1.62e-0317642536
GeneFamilyApolipoproteins

APOB APOL2

2.48e-0321642405
GeneFamilyPWWP domain containing

NSD1 MSH6

2.72e-03226421147
CoexpressionGSE27786_BCELL_VS_MONO_MAC_UP

UBR1 SLF1 MYCBP2 CCT7 CREBRF NAA35 SETD2 FASN

1.71e-062001078M4817
CoexpressionFISCHER_DREAM_TARGETS

KIF18A SLF1 RBL1 PKP4 CKAP5 HEATR1 MCM10 SS18 KIF20B POLR1F MSH6 FAM111A FEN1 CCDC15 NEIL3 PRIMPOL

1.99e-0696910716M149
CoexpressionKIM_MYC_AMPLIFICATION_TARGETS_DN

DPYSL3 ATL3 HEATR1 GRHL2 FAM111A ADAMTS18

3.12e-06981076M6319
CoexpressionHOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP

ABR RBL1 CKAP5 MCM10 FAM111A FEN1 RPA1

3.22e-061531077M5588
CoexpressionHOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP

ABR RBL1 CKAP5 MCM10 FAM111A FEN1 RPA1

3.51e-061551077MM1259
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL

KIF18A REXO5 RBL1 CKAP5 ATL3 NCF2 MCM10 KIF20B FAM111A FEN1 NEIL3

4.25e-0647810711M45785
CoexpressionKINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP

UBR1 KIF18A SLF1 PKP4 CKAP5 MCM10 SS18 KIF20B MSH6 DCUN1D1 FAM111A FEN1 PKP1 NEIL3 KDSR RPA1 PRIMPOL DYRK3

4.60e-06129010718M80
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

KIF18A MCM10 KIF20B MLKL MSH6 FEN1 NEIL3 APOL2 LNX1 RPA1

6.03e-0640210710MM454
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_NK_CELL

KIF18A REXO5 SLF1 RBL1 CKAP5 MCM10 KIF20B MSH6 FAM111A FEN1 NEIL3 PRIMPOL

2.70e-0569410712M45767
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

MAGEA3 KIF18A CKAP5 KIF20B POLR1F ARHGAP5 MSH6 DCUN1D1 FEN1 BOD1L1 ACAP2 AHNAK2

3.91e-0572110712M10237
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_DN

DOCK2 MYCBP2 NSD1 ARMCX2 JMJD1C P2RX4

4.77e-051581076M372
CoexpressionLEE_BMP2_TARGETS_DN

PPAN SLF1 CCT7 HEATR1 MCM10 POLR1F MSH6 MB21D2 FAM111A SH3PXD2A FEN1 SECISBP2 RPA1

8.15e-0590410713M2325
CoexpressionGSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN

ACAT1 LARS2 KIF20B MLKL FAM111A ACAP2

8.96e-051771076M6703
CoexpressionLEE_BMP2_TARGETS_DN

PPAN SLF1 CCT7 HEATR1 MCM10 POLR1F MSH6 MB21D2 FAM111A SH3PXD2A FEN1 SECISBP2 RPA1

9.92e-0592210713MM1068
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DOCK2 UBR1 SLF1 MYCBP2 NSD1 SH2D2A AP3M1 JMJD1C CREBRF SETD2 FAM111A TBRG1 SECISBP2 MACF1 BOD1L1 RPA1 ACAP2

1.12e-04149210717M40023
CoexpressionALCALAY_AML_BY_NPM1_LOCALIZATION_DN

ACAT1 XPA MCM10 FAAH ABCG2 RPA1

1.18e-041861076M19867
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP

KIF18A SLF1 RBL1 CKAP5 MCM10 KIF20B MSH6 FAM111A FEN1 RPA1

1.30e-0457810710M2368
CoexpressionGSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_UP

DOCK2 ACAT1 AP3M1 CASP12 DNAH12 CCDC15

1.48e-041941076M3540
CoexpressionMYLLYKANGAS_AMPLIFICATION_HOT_SPOT_18

SS18 KDSR

1.64e-0451072M12820
CoexpressionGSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_UP

LCAT MCM10 FASN FAM111A FEN1 RPA1

1.65e-041981076M6361
CoexpressionGSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP

FBXW10 MYCBP2 SH2D2A FAAH ARHGAP5 P2RX4

1.65e-041981076M6025
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP

KIF18A SLF1 RBL1 CKAP5 MCM10 KIF20B MSH6 FAM111A FEN1 RPA1

1.69e-0459710710MM1309
CoexpressionGSE27786_NEUTROPHIL_VS_MONO_MAC_DN

SS18 MLKL P2RX4 DCUN1D2 FEN1 NIPAL2

1.70e-041991076M4883
CoexpressionGSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN

PDSS2 PKP4 LARS2 EPS15L1 RPA1 AHNAK2

1.75e-042001076M4538
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP

ACAT1 PKP4 FASN BOD1L1 ABCG2 KDSR

1.75e-042001076M6653
CoexpressionGSE17721_CTRL_VS_POLYIC_12H_BMDC_UP

MYCBP2 XPA ADCY2 MSH6 FASN FAM111A

1.75e-042001076M3719
CoexpressionGSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP

RTCB PKP4 MSH6 FASN FAM111A CCDC15

1.75e-042001076M7308
CoexpressionGSE3982_NKCELL_VS_TH2_DN

KIF18A RTCB CCT7 HEATR1 KIF20B ABCG2

1.75e-042001076M5598
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

CACNA2D1 HCAR2 CACNA2D2 ARMCX2 CREBRF CASP12 DCUN1D1 P2RX4 LGALSL MACF1 ABCG2

1.79e-0472110711M1999
CoexpressionHAY_BONE_MARROW_ERYTHROBLAST

KIF18A REXO5 SELENBP1 RTCB ACAT1 PKP4 CKAP5 CCT7 MCM10 KIF20B MSH6 FEN1 CCDC15 RPA1 DYRK3

2.02e-04127110715M39197
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_CYCLING_DC_CELL

KIF18A PDSS2 SLF1 ACAT1 RBL1 PKP4 CKAP5 MCM10 KIF20B MSH6 FAM111A FEN1 NEIL3 PPIE RPA1 PRIMPOL

2.11e-04142310716M45722
CoexpressionBLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_DN

MYO1A MCM10 FASN FEN1

2.82e-04771074M34011
CoexpressionKYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP

APOB KIF20B B4GALT1 ARHGAP5

2.82e-04771074M1992
CoexpressionGEORGES_TARGETS_OF_MIR192_AND_MIR215

KIF18A SLF1 PKP4 MCM10 SS18 KIF20B MSH6 FEN1 CCDC15 MACF1 NEIL3 PRIMPOL

2.87e-0489210712M18120
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP

KIF18A SLF1 RBL1 ATL3 HEATR1 SS18 KIF20B MSH6 DCUN1D1 FEN1

3.10e-0464410710M10501
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

KIF18A SLF1 RBL1 SLC26A5 CKAP5 NSD1 HEATR1 MCM10 LARS2 KIF20B POLR1F ARHGAP5 MSH6 ST6GAL2 NAA35 FASN PKP1 MACF1 BOD1L1 RPA1 DYRK3

8.86e-07125710621facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

UBR1 CACNA2D1 PKP4 CKAP5 AP3M1 KIF20B ARHGAP5 EPS15L1 CCDC15 FMN2 MACF1 BOD1L1 ACAP2 PRIMPOL

2.98e-0662910614Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

KIF18A DPYSL3 SLF1 CACNA2D2 RBL1 SLC26A5 CKAP5 HEATR1 MCM10 LARS2 KIF20B ARHGAP5 ST6GAL2 FASN CCDC15 ADAMTS18 MACF1 BOD1L1

4.81e-06106010618facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

KIF18A SLF1 RBL1 SLC26A5 CKAP5 NSD1 HEATR1 MCM10 LARS2 KIF20B POLR1F ARHGAP5 MSH6 ST6GAL2 NAA35 FASN PKP1 MACF1 BOD1L1 RPA1 DYRK3

9.21e-06145910621facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

MYCBP2 PKP4 HEATR1 AP3M1 JMJD1C ARHGAP5 EPS15L1 FASN MACF1 RPA1 ACAP2 PRIMPOL

2.50e-0556410612Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

KIF18A SLF1 SLC26A5 CKAP5 NSD1 XPA HEATR1 SS18 KIF20B FAAH POLR1F ARHGAP5 MSH6 ST6GAL2 NAA35 FEN1 PKP1 ADAMTS18 MACF1 BOD1L1

3.43e-05146810620facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000

KIF18A CACNA2D1 NAALAD2 RBL1 ABCC9 MCM10 ADCY2 KIF20B CASP12 DCUN1D1 MB21D2 FAM111A NEIL3 KDSR

5.68e-0581910614gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

KIF18A SLF1 SLC26A5 CKAP5 NSD1 XPA HEATR1 SS18 KIF20B POLR1F ARHGAP5 MSH6 ST6GAL2 NAA35 FEN1 MACF1 BOD1L1

1.35e-04124110617facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000

UBR1 CACNA2D1 ABCC9 NCF2 CASP12 LGALSL

1.69e-041631066gudmap_kidney_P0_JuxtaGlom_Ren1_k2_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

KIF18A DPYSL3 SLF1 CACNA2D2 RBL1 SLC26A5 CKAP5 HEATR1 MCM10 LARS2 KIF20B ARHGAP5 ST6GAL2 FASN CCDC15 ADAMTS18 MACF1 BOD1L1

2.10e-04141410618facebase_RNAseq_e10.5_Emin_MedNas_2500
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

CACNA2D1 CDHR1 MSH6 DCUN1D1 PKP1 RPA1 ACAP2

3.15e-071841077ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 KIF18A SLF1 RBL1 MCM10 KIF20B NEIL3

4.06e-071911077bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellEndothelial-Endothelial-D_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

KIF18A RBL1 CKAP5 KIF20B FAM111A FEN1 NEIL3

4.06e-071911077a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

KIF18A CKAP5 MCM10 KIF20B FAM111A FEN1 NEIL3

4.50e-071941077a12b64945e10f00aa983678a02586c59badc1570
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF18A CKAP5 MCM10 KIF20B FAM111A FEN1 NEIL3

4.83e-0719610779591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLF1 RBL1 MCM10 KIF20B FEN1 CCDC15 RPA1

4.83e-071961077df366d76ea55f49e349d622effa57c1535df8400
ToppCell(3)_MNP-(3)_Macrophage_Dividing|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

KIF18A CKAP5 MCM10 KIF20B FAM111A FEN1 NEIL3

5.00e-071971077048bc4f8fd5d4f394e2384700640f72042336597
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

KIF18A MCM10 KIF20B FAM111A FEN1 CCDC15 NEIL3

5.17e-0719810776a10bb81817ab606f1f5a2bd8cfe77ef2fb3f2fb
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA2D1 PKP4 GRHL2 ADCY2 FCGBP ATP12A LNX1

5.53e-072001077682960e28542a3d6c119047cd0131941932cfdea
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF18A MCM10 KIF20B FAM111A FEN1 CCDC15 NEIL3

5.53e-07200107763f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCellfacs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT ACAT1 LARS2 NELL1 MB21D2 ABCG2

3.39e-061691076ee27bcfe3f9a295ec5fb0a375d77d1050e5cbaad
ToppCellfacs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT ACAT1 LARS2 NELL1 MB21D2 ABCG2

3.39e-061691076922086f218135b734b7d370b871923e50141edce
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REXO5 SH2D2A KIF20B MSH6 NEIL3 RPA1

3.63e-0617110761eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBL1 MCM10 GRHL2 KIF20B FEN1 NEIL3

3.76e-061721076eba1568d4307e91c94fc616549057cbed8df5840
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A HCAR2 REXO5 MCM10 KIF20B NEIL3

4.01e-06174107684da9faff088d05233183b425385beb054c92d1b
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF18A PKP4 MCM10 DNAH12 NEIL3 ABCG2

4.72e-061791076e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A REXO5 CKAP5 MCM10 KIF20B NEIL3

5.71e-06185107630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 CKAP5 MCM10 KIF20B FCGBP NEIL3

6.07e-06187107673931a5ea73799095daff100b5f18853c57c74dc
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLF1 MCM10 FAM111A FEN1 CCDC15 NEIL3

6.85e-06191107650854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.49e-061941076f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLF1 RBL1 MCM10 KIF20B FEN1 CCDC15

7.71e-061951076cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 KIF18A SLF1 MCM10 KIF20B NEIL3

7.71e-0619510767e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A RBL1 MCM10 KIF20B FEN1 NEIL3

7.71e-06195107693c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

KIF18A RBL1 CKAP5 MCM10 KIF20B NEIL3

7.71e-061951076764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MYCBP2 NSD1 FMN2 MACF1 BOD1L1

7.71e-0619510763e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF18A RBL1 MCM10 KIF20B FEN1 NEIL3

7.71e-0619510761a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLF1 RBL1 MCM10 KIF20B FEN1 CCDC15

7.71e-06195107656d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.94e-0619610766d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCellBAL-Control-Myeloid-Myeloid|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.94e-061961076bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF18A MCM10 KIF20B FEN1 CCDC15 NEIL3

7.94e-0619610761d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF18A RBL1 MCM10 KIF20B FEN1 NEIL3

7.94e-0619610761964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.94e-0619610763dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.94e-0619610764f649e3bfd21f21682678828673843a7d51c4ff2
ToppCellBAL-Control-Myeloid-Myeloid|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.94e-061961076799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF18A KIF20B FAM111A FEN1 CCDC15 NEIL3

7.94e-06196107634bd155e6d848eb53d613997c0e244535de30ba3
ToppCell(05)_Secretory|World / shred by cell type by condition

HCAR2 SELENBP1 B4GALT1 FASN FCGBP ATP12A

7.94e-0619610768032c25b51ef96aeba28cc52686a2bd45213453d
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

7.94e-0619610760c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIF18A MCM10 KIF20B FEN1 CCDC15 NEIL3

8.17e-06197107684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellControl-Myeloid-proliferating_Myeloid_cells|Control / Disease group,lineage and cell class (2021.01.30)

KIF18A REXO5 MCM10 KIF20B FEN1 NEIL3

8.17e-061971076ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIF18A MCM10 KIF20B FEN1 CCDC15 NEIL3

8.17e-0619710768b616cde333bdbc0c591035ad9e4949155866245
ToppCellSepsis-Int-URO-Others-RBC|Int-URO / Disease, condition lineage and cell class

SELENBP1 KIF20B FAAH B4GALT1 SLC12A3 FEN1

8.41e-06198107629203aaa5c1844f72289e03f585cd5e7fc498a9a
ToppCellSepsis-Int-URO-Others|Int-URO / Disease, condition lineage and cell class

SELENBP1 KIF20B FAAH B4GALT1 SLC12A3 FEN1

8.41e-06198107667f721ea8e60042317ba12efd584f56b07cfb29d
ToppCellMNPs-Dividing_Macrophages|MNPs / lung cells shred on cell class, cell subclass, sample id

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.66e-0619910765952980d0ece5d73f3e9f340c56a38b34d2f2309
ToppCell(5)_Dendritic_cell-(52)_cycling_DCs|(5)_Dendritic_cell / shred on Cell_type and subtype

KIF18A CKAP5 KIF20B NELL1 FAM111A FEN1

8.66e-061991076d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCell10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

MCM10 KIF20B FAM111A FEN1 NEIL3 ABCG2

8.66e-061991076dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.66e-06199107688d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIF18A REXO5 CKAP5 MCM10 KIF20B NEIL3

8.66e-061991076be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KIF18A CKAP5 MCM10 KIF20B ST6GAL2 NEIL3

8.91e-0620010764cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-0620010763835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCellBAL-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-062001076535f6fba8d03873ba35c9949579161dc41cd7a60
ToppCellSevere_COVID-19-T/NK-proliferating_T/NK|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-06200107652265e761a961f3724b388285e0919bd58847138
ToppCellBAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-0620010763c3ac587ad98e3f6be809eac18c7742a23140de1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-0620010769359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCellBAL-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-0620010765c84aaedac9f27da0da0493dab7c8f7a4d66888c
ToppCellBAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-06200107660d11275f06490f86f400a2802492f9c1b570400
ToppCellMacroglial-Astrocytes-GFAP---|Macroglial / cells hierarchy compared to all cells using T-Statistic

DPYSL3 ABR LCAT ADCY2 ADAMTS18 FMN2

8.91e-06200107688d66550781a3c9102ff7455f5cff6fb072943cd
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-0620010769c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Stem_cells|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-062001076008f137920cc3b599376706803c111d1d0ec17ef
ToppCellMacroglial-Astrocytes-GFAP-|Macroglial / cells hierarchy compared to all cells using T-Statistic

DPYSL3 ABR LCAT ADCY2 ADAMTS18 FMN2

8.91e-062001076d6a059b0ef763c281c60b1ac76da6079ea822f80
ToppCellMacroglial-Astrocytes-GFAP--|Macroglial / cells hierarchy compared to all cells using T-Statistic

DPYSL3 ABR LCAT ADCY2 ADAMTS18 FMN2

8.91e-06200107616269fa4adb28fc6ed032bbdba8781237dd0d249
ToppCellMacroglial-Astrocytes-GFAP----L1-2|Macroglial / cells hierarchy compared to all cells using T-Statistic

DPYSL3 ABR LCAT ADCY2 ADAMTS18 FMN2

8.91e-062001076c6f43bbbd5df5f2c19ae385f1a6b6a330abede2f
ToppCellBAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-062001076dd7ad295ab3ba4c19babffb1625900db414bb5a9
ToppCellBAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIF18A SH2D2A MCM10 KIF20B FEN1 NEIL3

8.91e-0620010760e44a55d65b72eb40543d3bde301f8598ac251c3
ToppCellMacroglial-Astrocytes-GFAP|Macroglial / cells hierarchy compared to all cells using T-Statistic

DPYSL3 ABR LCAT ADCY2 ADAMTS18 FMN2

8.91e-06200107679634b1086934412ae92f259ab43554ce545008f
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-0620010761b65c97e8123d0572d31525d6a10bc7f16857959
ToppCellCOVID-19-Lymphoid-Proliferating_CD8_T_cells|Lymphoid / Condition, Lineage and Cell class

CKAP5 MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-0620010764556bb626ca1a00a6db13d2adb35acb8ba848f9c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Stem_cells-Neuroepithelial_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIF18A MCM10 KIF20B FAM111A FEN1 NEIL3

8.91e-0620010760e119c2742f2be19fde8890d1227bf277ead976f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

CPAMD8 DNAH10 CACNA2D2 LCAT MB21D2 DYRK3

8.91e-062001076be83f442179ba4217d12f0458059586ff3130991
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 ABR DNAH10 NCF2 PLA2G2D

3.87e-051571075ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 REXO5 MCM10 KIF20B SH3PXD2A

4.24e-051601075830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELENBP1 APOB SLC15A1 ABCG2 ATP12A

4.50e-051621075bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MCM10 CCDC15 NEIL3 ATP12A

4.77e-0516410751642a67c66eeb77a218e7814e3cfe517d9822955
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A MCM10 CCDC15 NEIL3 ATP12A

4.77e-05164107525758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

RBL1 MCM10 KIF20B FAM111A NEIL3

5.50e-051691075bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellileum|World / shred on tissue and cell subclass

MYO1A CDHR1 APOB SLC15A1 ABCG2

5.65e-0517010759f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 FCGBP SLC12A3 PKP1 DYRK3

6.14e-0517310757c5e4809205ce1a0a301c15442af00a2e2b9b301
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A REXO5 MCM10 KIF20B NEIL3

6.14e-051731075a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellFLU-Healthy-5|Healthy / Virus stimulation, Condition and Cluster

NCF2 KIF20B MB21D2 FAM111A ABCG2

6.14e-0517310758c218ec1ba927e9312f3df5f312395e907ab64ab
ToppCellFLU-Healthy-5|FLU / Virus stimulation, Condition and Cluster

NCF2 KIF20B MB21D2 FAM111A ABCG2

6.14e-051731075bd4f06d971f9d138749094047c9337dfbaf5da31
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBL1 FAM111A FEN1 NEIL3 RPA1

6.31e-051741075c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 PKP4 MCM10 NELL1 SH3PXD2A

6.31e-051741075f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A REXO5 CKAP5 KIF20B NEIL3

6.31e-051741075dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKP4 MCM10 KIF20B NIPAL2 NEIL3

6.49e-0517510759142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

DPYSL3 F5 NELL1 IGSF22 FMN2

6.49e-0517510754db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

DPYSL3 F5 NELL1 IGSF22 FMN2

6.49e-0517510758d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A PDSS2 RBL1 SH2D2A KIF20B

6.49e-0517510758958c5c30437d20a4abd70d7527990f7e2a68b93
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF18A MCM10 DNAH12 NEIL3 ABCG2

6.66e-0517610758813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKAP5 NSD1 JMJD1C ARHGAP5 MACF1

6.66e-051761075749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF18A CKAP5 KIF20B FEN1 NEIL3

6.66e-0517610758385435074cc5235b7af7424974f609388fc2cff
ToppCell(01)_Cycling_Basal_(homeostasis)|World / shred by cell type and Timepoint

KIF18A CKAP5 KIF20B FAM111A NEIL3

6.84e-05177107505c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCelldroplet-Kidney-nan-18m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT SELENBP1 APOB LARS2 SLC12A3

7.41e-051801075cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A FAM111A FEN1 PKP1 NEIL3

7.61e-051811075b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A FAM111A FEN1 PKP1 NEIL3

7.61e-051811075c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A REXO5 CKAP5 KIF20B NEIL3

7.81e-051821075336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A REXO5 MCM10 KIF20B NEIL3

7.81e-0518210753948422707d6d5e021bcd7158e2eb69143613f62
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 NSD1 SH2D2A MACF1 BOD1L1

7.81e-051821075e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A REXO5 MCM10 KIF20B NEIL3

7.81e-051821075fe46819c153a81911864473badc794f243705f98
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 NSD1 SH2D2A MACF1 BOD1L1

7.81e-0518210751710eab3037a87609d21838be2d2d29c3bc36651
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

GRHL2 ADCY2 FCGBP ATP12A LNX1

8.01e-051831075940cbe298e9c53b5622af09264586ed823d3141f
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 NSD1 JMJD1C SETD2 MACF1

8.22e-0518410751154a5ad7b8512272b7476f949ddac350910bfb7
DrugPyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; MCF7; HT_HG-U133A

KIF18A ABR RBL1 MCM10 FAAH MSH6 MACF1 DYRK3

2.68e-0618510785439_DN
Diseasecortical thickness

CPAMD8 FBXW10 MYCBP2 ABCC9 AP3M1 JMJD1C KIF20B POLR1F NELL1 SH3PXD2A MTHFR ADAMTS18 FMN2 MACF1 LNX1

9.42e-06111310515EFO_0004840
Diseasemale infertility (is_implicated_in)

ACTL7A MTHFR

1.25e-0521052DOID:12336 (is_implicated_in)
DiseaseReplication Error Phenotype

MSH6 SETD2 MTHFR

1.93e-05151053C1721098
DiseaseMicrosatellite Instability

MSH6 SETD2 MTHFR

1.93e-05151053C0920269
Diseasecoffee consumption, cups of coffee per day measurement

EFCAB5 PDSS2 ABCG2

2.37e-05161053EFO_0004330, EFO_0006782
Diseaseresponse to acetylsalicylate

CACNA2D1 SH2D2A SETD2

2.37e-05161053GO_1903492
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

HCAR2 DNAH10 APOB LCAT JMJD1C SLC12A3 MACF1

2.70e-052431057EFO_0004612, EFO_0020944
Diseasebrain measurement, neuroimaging measurement

DPYSL3 SLF1 MYLK2 POLR1F NELL1 SH3PXD2A ADAMTS18 MACF1 ABCG2 LNX1

2.76e-0555010510EFO_0004346, EFO_0004464
DiseaseBudd-Chiari syndrome (is_implicated_in)

F5 MTHFR

3.75e-0531052DOID:11512 (is_implicated_in)
DiseaseSotos' syndrome

NSD1 SETD2

7.49e-0541052C0175695
Diseasenon-arteritic anterior ischemic optic neuropathy (is_implicated_in)

F5 MTHFR

1.25e-0451052DOID:0050864 (is_implicated_in)
Diseasemacrophage inflammatory protein 1b measurement

CACNA2D2 SH2D2A LARS2 SETD2 ZNF852

1.29e-041361055EFO_0008219
Diseasecortical surface area measurement, neuroimaging measurement

EFCAB5 DPYSL3 SLF1 POLR1F NELL1 ADAMTS18

1.66e-042271056EFO_0004346, EFO_0010736
Diseasecholesteryl esters to total lipids in large LDL percentage

APOB LCAT JMJD1C

1.83e-04311053EFO_0022249
DiseaseColorectal Carcinoma

CPAMD8 SELENBP1 APOB F5 NELL1 MSH6 MTHFR FEN1 ADAMTS18 ABCG2

2.06e-0470210510C0009402
Diseasebeta-citrylglutamate measurement

NAALAD2 JMJD1C

2.60e-0471052EFO_0800060
Diseaseretinal vein occlusion (is_implicated_in)

F5 MTHFR

2.60e-0471052DOID:1727 (is_implicated_in)
Diseaseclear cell renal cell carcinoma (is_implicated_in)

SETD2 MTHFR

3.46e-0481052DOID:4467 (is_implicated_in)
DiseaseThrombophilia due to thrombin defect

F5 MTHFR

3.46e-0481052cv:C3160733
Diseasehearing impairment

MYO1A CACNA2D2 SLC26A5 GRHL2

4.23e-04981054C1384666
Diseasecorpus callosum volume measurement

CACNA2D1 POLR1F NELL1 LNX1

4.57e-041001054EFO_0010299
DiseaseShortened QT interval

CACNA2D1 ABCC9

6.76e-04111052C0151879
DiseaseSCHIZOPHRENIA

MTHFR APOL2

6.76e-04111052181500
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

HCAR2 DNAH10 APOB JMJD1C MACF1

7.59e-042001055EFO_0004611, EFO_0020945
Diseasecholesteryl esters to total lipids in IDL percentage

APOB JMJD1C MACF1

7.60e-04501053EFO_0022247
Diseasesleep duration, high density lipoprotein cholesterol measurement

APOB JMJD1C SLC12A3 MACF1

9.35e-041211054EFO_0004612, EFO_0005271
DiseaseAcute Cerebrovascular Accidents

F5 SH3PXD2A MTHFR

9.52e-04541053C0751956
DiseaseCrohn's disease

GLYAT CACNA2D1 LCAT NELL1 LGALSL PLA2G2D FEN1

1.03e-034411057EFO_0000384
Diseasetriglycerides in large VLDL measurement

DNAH10 APOB JMJD1C

1.06e-03561053EFO_0022178
DiseaseAdenocarcinoma Of Esophagus

DOCK2 NELL1

1.11e-03141052C0279628
DiseaseEndometrial Neoplasms

ABCC9 MSH6 MTHFR

1.17e-03581053C0014170
Diseasewhite matter integrity

EPS15L1 SH3PXD2A ADAMTS18 LNX1

1.22e-031301054EFO_0004641
DiseaseLymphoma, Follicular, Grade 2

MTHFR KDSR

1.28e-03151052C1956132
DiseaseLymphoma, Follicular, Grade 3

MTHFR KDSR

1.28e-03151052C1956131
DiseaseLymphoma, Follicular, Grade 1

MTHFR KDSR

1.28e-03151052C1956130
DiseaseLymphoma, Large-Cell, Follicular

MTHFR KDSR

1.28e-03151052C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

MTHFR KDSR

1.28e-03151052C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

MTHFR KDSR

1.28e-03151052C0079758
Diseaseresponse to statin, LDL cholesterol change measurement

APOB ABCG2

1.28e-03151052EFO_0007804, GO_0036273
Diseasecholesterol to total lipids in IDL percentage

APOB JMJD1C MACF1

1.29e-03601053EFO_0022233
Diseasetriglycerides in small VLDL measurement

DNAH10 APOB JMJD1C

1.36e-03611053EFO_0022145
Diseasefree cholesterol in very large VLDL measurement

DNAH10 APOB JMJD1C

1.36e-03611053EFO_0022274
Diseasephospholipids in large VLDL measurement

DNAH10 APOB JMJD1C

1.42e-03621053EFO_0022169
DiseaseCerebrovascular accident

F5 SH3PXD2A MTHFR

1.42e-03621053C0038454
Diseasetotal lipids in very large VLDL measurement

DNAH10 APOB JMJD1C

1.42e-03621053EFO_0022313
Diseasephospholipids in very large VLDL measurement

DNAH10 APOB JMJD1C

1.42e-03621053EFO_0022299
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

F5 JMJD1C

1.46e-03161052EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseasesickle cell anemia (is_implicated_in)

APOB MTHFR

1.46e-03161052DOID:10923 (is_implicated_in)
DiseaseMalignant neoplasm of ovary

DPH1 SELENBP1 MSH6 FASN

1.48e-031371054C1140680
Diseaseneuroimaging measurement

DPYSL3 JMJD1C KIF20B POLR1F NELL1 SH3PXD2A NIPAL2 ADAMTS18 MACF1 ABCG2 LNX1

1.50e-03106910511EFO_0004346
Diseasecholesterol in large VLDL measurement

DNAH10 APOB JMJD1C

1.63e-03651053EFO_0021902
DiseaseCannabis Dependence

FAAH APOL2

1.65e-03171052C0006870
Diseasehigh altitude adaptation

HCAR2 MTHFR

1.65e-03171052EFO_0009105
DiseaseVascular Diseases

SLC12A3 MTHFR

1.65e-03171052C0042373
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

APOB LCAT JMJD1C MACF1

1.78e-031441054EFO_0004611, EFO_0020943
Diseasestem Cell Factor measurement

LCAT F5 AHNAK2

1.78e-03671053EFO_0008291
Diseasetotal lipids in large VLDL

DNAH10 APOB JMJD1C

1.78e-03671053EFO_0022175
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

APOB JMJD1C MACF1

1.78e-03671053EFO_0008595, EFO_0020946
Diseaselysophosphatidylcholine 22:6 measurement

CACNA2D1 FEN1

1.85e-03181052EFO_0010365
DiseaseSchizophrenia

MTHFR APOL2

1.85e-03181052cv:C0036341
Diseasetriglycerides to phosphoglycerides ratio

DNAH10 APOB JMJD1C

1.86e-03681053EFO_0022327
Diseasefree cholesterol in large VLDL measurement

DNAH10 APOB JMJD1C

1.86e-03681053EFO_0022265
Diseasetriglyceride measurement, phospholipid measurement

HCAR2 DNAH10 APOB JMJD1C

1.87e-031461054EFO_0004530, EFO_0004639
Diseaseserum metabolite measurement

GLYAT CACNA2D1 PDSS2 NAALAD2 CKAP5 APOB GRHL2 FAAH ABCG2 LNX1

2.01e-0394510510EFO_0005653
DiseaseEndometrial Carcinoma

ABCC9 MSH6 MTHFR

2.19e-03721053C0476089
DiseaseDrugs used in diabetes use measurement

MYCBP2 NSD1 JMJD1C LGALSL MACF1

2.22e-032551055EFO_0009924
DiseaseLiver carcinoma

MAGEA3 KIF18A LCAT MCM10 FASN PKP1 NEIL3

2.27e-035071057C2239176
DiseaseLymphoma, Follicular

MTHFR KDSR

2.29e-03201052C0024301
Diseasecholesteryl ester measurement

DNAH10 APOB LCAT JMJD1C FEN1

2.29e-032571055EFO_0010351
Diseasefree cholesterol to total lipids in large LDL percentage

APOB JMJD1C MACF1

2.36e-03741053EFO_0022280
DiseaseDeep Vein Thrombosis

F5 MTHFR

2.52e-03211052C0149871
Diseasechronic myeloid leukemia (is_implicated_in)

MTHFR ABCG2

2.52e-03211052DOID:8552 (is_implicated_in)
DiseaseVenous Thrombosis

F5 MTHFR

2.52e-03211052C0042487
Diseasecardiovascular system disease (is_implicated_in)

UBR1 MTHFR

2.52e-03211052DOID:1287 (is_implicated_in)
Diseaseprothrombin time measurement

F5 JMJD1C

2.52e-03211052EFO_0008390
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

CKAP5 F5

2.52e-03211052EFO_0004286, EFO_0004792
Diseasedocosahexaenoic acid to total fatty acids percentage

APOB JMJD1C

2.52e-03211052EFO_0022262
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

HCAR2 DNAH10 APOB JMJD1C MACF1

2.58e-032641055EFO_0008317, EFO_0020944
Diseasecortical surface area measurement

EFCAB5 CACNA2D1 CPAMD8 DPYSL3 ABR MYCBP2 KIF20B POLR1F NELL1 ADAMTS18 MACF1 LNX1

3.00e-03134510512EFO_0010736
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

HCAR2 DNAH10 APOB JMJD1C MACF1

3.12e-032761055EFO_0004612, EFO_0020943
DiseaseColorectal Neoplasms

CPAMD8 SELENBP1 MTHFR FEN1 ABCG2

3.17e-032771055C0009404
DiseaseCoronary heart disease

APOB MTHFR

3.29e-03241052C0010068
DiseaseBrugada Syndrome (disorder)

CACNA2D1 ABCC9

3.29e-03241052C1142166
Diseasenephrotic syndrome (biomarker_via_orthology)

ACAT1 APOB

3.29e-03241052DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NKIAMKNVGGIPALL

PKP4

606

Q99569
IVDKIMGKGQIQLDP

ABR

586

Q12979
INGLLSGDKVKPVLM

EPS15L1

141

Q9UBC2
LELVAKQNPNVKMGG

B4GALT1

151

P15291
VAKVMKEFVGGNTPN

APOL2

191

Q9BQE5
LIQTKDNPMKAVGVL

CDHR1

691

Q96JP9
DGPGEKKNQLILGVM

CACNA2D2

511

Q9NY47
GPNMGQKLEILIKDT

CREBRF

586

Q8IUR6
VPGGVKTIEANGKMV

DPYSL3

51

Q14195
KTIEANGKMVIPGGI

DPYSL3

56

Q14195
NCMKVLKANGRGDPV

FBXW10

646

Q5XX13
KEILSNINGIMKPGL

ABCG2

61

Q9UNQ0
QLKNMVKSLPGGLDA

ABCC9

1426

O60706
GMICANQKGQEIKPG

ACSM4

376

P0C7M7
ANVEKMGIKKPQPGQ

ACAP2

481

Q15057
GPKQNMGKTIEGITV

AP3M1

296

Q9Y2T2
GPLKDMQFGNKIAIL

PDSS2

176

Q86YH6
QAQAKKVALQMPEGL

DPH1

71

Q9BZG8
KPKVIIMQACRGNGA

CASP12

211

Q6UXS9
KNPGQKGLDLEMAIA

DCUN1D1

166

Q96GG9
KLGGLPIIANMINKT

ARMCX2

426

Q7L311
LVFEILMQGKNPGIA

ADAMTS18

841

Q8TE60
LKMGKAEGVINAEIP

FBXL19

126

Q6PCT2
VKVPEKTEGGNNMAL

MROH7

421

Q68CQ1
KQMVGGQQLPALAAK

NSD1

2581

Q96L73
KAGKFDIIPTMINIG

P2RX4

326

Q99571
KQLGLKNIMALRGDP

MTHFR

146

P42898
GKKVLVMGIVDLNPE

LGALSL

51

Q3ZCW2
GDNQIMPKAGLLIIV

MAGEA3

191

P43357
GMVQKLDQKLPVANE

MB21D2

71

Q8IYB1
LMDQNVLPGVGNIIK

NEIL3

181

Q8TAT5
VMPGNIVFVLKKGND

NCF2

261

P19878
GPVLMAEAVKKVNRG

MYO1A

891

Q9UBC5
HLLKKKMPIQNGGAN

HCAR2

161

Q8TDS4
EKEMGLLSQNGHIPK

KIF18A

516

Q8NI77
GQENVPIMKKAVIGD

ATP12A

451

P54707
MPVNAGGKVQESQKP

JMJD1C

1236

Q15652
NGGKPKAINQEMFKL

GLYAT

156

Q6IB77
KNPGQKGLDLEMAVA

DCUN1D2

166

Q6PH85
EVGEKTPGQAGQAKM

MYLK2

206

Q9H1R3
GCIMQPVKDLLKGQS

KIF20B

131

Q96Q89
QGQGPIAAKMIKAAI

DNAH12

2531

Q6ZR08
KVVNIQKDPGESLGM

LNX1

506

Q8TBB1
VGILNANPMKPKDGS

MCM10

351

Q7L590
KLSDGIGVMLPQVLK

MSH6

646

P52701
LGLIKPLEMLQDQGK

MLKL

36

Q8NB16
KGIIQDGKIIFMPNG

NELL1

201

Q92832
KLLPVKQLAGGMVSL

MACF1

1731

Q9UPN3
AAIMQKGDTNIKPIL

RPA1

11

P27694
QATLLDGKQGKVIMP

BOD1L1

1371

Q8NFC6
KGMIPKSVIQNVLQE

EFCAB5

301

A4FU69
MKAEIIQRLQGPKAG

ADCY2

256

Q08462
PGAKAGVKLEVANMQ

APOB

856

P04114
MGPNIKQHVKNLGIP

CKAP5

931

Q14008
MGIQGLAKLIADVAP

FEN1

1

P39748
KEITDLPGMQIVKQG

IGSF22

551

Q8N9C0
LPGMQIVKQGAVHKL

IGSF22

556

Q8N9C0
QKGVKGLPLMIQIDT

GRHL2

381

Q6ISB3
KLGQNKICFIPGMVG

DOCK2

1076

Q92608
GRPMVLAGDKAKQVQ

CACNA2D1

431

P54289
VNGVDMKLPVVLANG

FCGBP

1331

Q9Y6R7
AVLKLKENGQQVPME

FAM111A

441

Q96PZ2
LETKVMALNGKPVGA

CPAMD8

421

Q8IZJ3
PGGKKVAVVLMDTQG

ATL3

131

Q6DD88
IKPMLVLASGDNQGI

LCAT

241

P04180
TKPGKLIGVANQKMI

HEATR1

651

Q9H583
QKGMKKSVGLPVAVQ

FAAH

536

O00519
KVTQQGLKMVVPGLD

FASN

1151

P49327
KLCETLKNGPGVMQV

FMN2

1476

Q9NZ56
QEALKQGMGPAKESV

DNAH10

2901

Q8IVF4
IKIGNKPAGRIQMLL

PPIE

146

Q9UNP9
FKPQGNIMGKVAKCI

SLC15A1

226

P46059
KQAQEKLGPVDMLVN

KDSR

106

Q06136
PPVVGIANKLKANLM

DYRK3

556

O43781
ANPGADGKKMVALLI

PRIMPOL

121

Q96LW4
MSQLIGLKEKGLPQI

PKP1

586

Q13835
RIKKGFVPNMQVEGV

RTCB

21

Q9Y3I0
KQGQAPVPMQKEGAG

SH2D2A

221

Q9NP31
MAVLINNKACGKIPV

LARS2

841

Q15031
MGLKLGPALKIQSQV

SAMD7

371

Q7Z3H4
KHTVNPNMKEDGILG

F5

406

P12259
RNPVENIMKILKGIG

RBL1

421

P28749
LKRKTGVNPAVIMGA

SLC26A5

556

P58743
DFGNIPGKQMLDKIQ

NIPAL2

341

Q9H841
LLPVQGKQRAIMGAA

ST6GAL2

51

Q96JF0
VKKSQLPVQLDLGGM

SECISBP2

441

Q96T21
QLKMIGIKKVQGGAL

CCT7

191

Q99832
LVVKGKRVAGGPQMI

SELENBP1

376

Q13228
GIPIGMLVLGNKVKA

MYCBP2

2611

O75592
MLEIDPQKVNINGGA

ACAT1

366

P24752
QKQMPEGKLNVDGFL

ARHGAP5

146

Q13017
IPIQGGILNLNKMVK

PLA2G2D

16

Q9UNK4
AAIMGDGPTKKVGNQ

ACTL7A

6

Q9Y615
KVQAGQMDVKLPEGQ

AHNAK2

3696

Q8IVF2
GQPIKTETQGIMLKA

CCDC15

381

Q0P6D6
QLQKEAVSGPMAGKP

nan

266

Q6ZSR9
VAKPNFVVMKLLAGG

NAA35

686

Q5VZE5
VVPVGASRGMKKLLQ

PPAN

201

Q9NQ55
RGKGEITPAAIQKML

SS18

11

Q15532
QMQLLDKFPIEGGQK

SH3PXD2A

51

Q5TCZ1
KKNLAGPVEIIGNIM

SH3PXD2A

331

Q5TCZ1
APNKLVGAAEAMKAG

REXO5

21

Q96IC2
QMLLEKLKGIPQLEG

UBR1

956

Q8IWV7
QAAGLGRMKPNILVV

SLC12A3

726

P55017
EPGQKLMGIVNKVSS

POLR1F

126

Q3B726
MLNGTKQKQVEGLPE

SLF1

746

Q9BQI6
KIENVQKTGFIKGPM

SETD2

31

Q9BYW2
TGGMANVKAAPKIID

XPA

56

P23025
GEKNLMNVLSVGKPL

ZNF852

491

Q6ZMS4
KMAGGARKLVQPIAL

TBRG1

161

Q3YBR2
GNKVKNAMLAGAIGI

NAALAD2

201

Q9Y3Q0