Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	Rab GDP-dissociation inhibitor activity	GDI1 GDI2	1.01e-05	2	64	2	GO:0005093
GeneOntologyMolecularFunction	pantothenate kinase activity	PANK2 PANK3	6.04e-05	4	64	2	GO:0004594
Domain	RabGDI	GDI1 GDI2	1.12e-05	2	63	2	IPR000806
Domain	GDI	GDI1 GDI2	6.69e-05	4	63	2	PF00996
Domain	Fumble	PANK2 PANK3	6.69e-05	4	63	2	PF03630
Domain	GDP_dissociation_inhibitor	GDI1 GDI2	6.69e-05	4	63	2	IPR018203
Domain	Type_II_PanK	PANK2 PANK3	6.69e-05	4	63	2	IPR004567
Domain	EGF_LAM_2	CELSR2 LAMA5 LAMC3	1.39e-04	30	63	3	PS50027
Domain	EGF_LAM_1	CELSR2 LAMA5 LAMC3	1.39e-04	30	63	3	PS01248
Domain	Laminin_EGF	CELSR2 LAMA5 LAMC3	2.22e-04	35	63	3	PF00053
Domain	EGF_Lam	CELSR2 LAMA5 LAMC3	2.22e-04	35	63	3	SM00180
Domain	Laminin_EGF	CELSR2 LAMA5 LAMC3	2.84e-04	38	63	3	IPR002049
Domain	LAMININ_IVA	LAMA5 LAMC3	3.09e-04	8	63	2	PS51115
Domain	Laminin_B	LAMA5 LAMC3	3.09e-04	8	63	2	PF00052
Domain	LamB	LAMA5 LAMC3	3.09e-04	8	63	2	SM00281
Domain	Laminin_IV	LAMA5 LAMC3	3.09e-04	8	63	2	IPR000034
Domain	MORN	ALS2 ANKMY1	9.93e-04	14	63	2	SM00698
Domain	MORN	ALS2 ANKMY1	1.14e-03	15	63	2	IPR003409
Domain	MORN	ALS2 ANKMY1	1.14e-03	15	63	2	PF02493
Domain	EGF	HEG1 CELSR2 LAMA5 LAMC3 LTBP2	1.17e-03	235	63	5	SM00181
Domain	Laminin_N	LAMA5 LAMC3	1.30e-03	16	63	2	IPR008211
Domain	LAMININ_NTER	LAMA5 LAMC3	1.30e-03	16	63	2	PS51117
Domain	Laminin_N	LAMA5 LAMC3	1.30e-03	16	63	2	PF00055
Domain	LamNT	LAMA5 LAMC3	1.30e-03	16	63	2	SM00136
Domain	EGF-like_dom	HEG1 CELSR2 LAMA5 LAMC3 LTBP2	1.52e-03	249	63	5	IPR000742
Domain	EGF_1	HEG1 CELSR2 LAMA5 LAMC3 LTBP2	1.68e-03	255	63	5	PS00022
Domain	EGF-like_CS	HEG1 CELSR2 LAMA5 LAMC3 LTBP2	1.86e-03	261	63	5	IPR013032
Domain	Growth_fac_rcpt_	CELSR2 LAMA5 LAMC3 LTBP2	1.90e-03	156	63	4	IPR009030
Domain	EGF_2	HEG1 CELSR2 LAMA5 LAMC3 LTBP2	1.99e-03	265	63	5	PS01186
Domain	ASX_HYDROXYL	HEG1 CELSR2 LTBP2	4.69e-03	100	63	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	HEG1 CELSR2 LTBP2	5.51e-03	106	63	3	IPR000152
Domain	TNFR/NGFR_Cys_rich_reg	CELSR2 LAMA5	5.53e-03	33	63	2	IPR001368
Domain	C1q_dom	ERFE EMILIN1	5.86e-03	34	63	2	IPR001073
Domain	C1Q	ERFE EMILIN1	5.86e-03	34	63	2	PS50871
Domain	LAM_G_DOMAIN	CELSR2 LAMA5	7.28e-03	38	63	2	PS50025
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PDIA4 CERS5 HEG1 GOPC CELSR2 AXL LOXL1 L1CAM LAMA5 KIRREL1 LAMC3 PTDSS2 LTBP2 EDEM1 PCSK9	3.54e-09	1201	64	15	35696571
Pubmed	Cell surface sialylation and fucosylation are regulated by L1 via phospholipase Cgamma and cooperate to modulate neurite outgrowth, cell survival and migration.	L1CAM PLCG1	3.33e-06	2	64	2	19048108
Pubmed	Distinct expression patterns of CD123 and CD34 on normal bone marrow B-cell precursors ("hematogones") and B lymphoblastic leukemia blasts.	CD34 IL3RA	3.33e-06	2	64	2	19762535
Pubmed	IL-13 induces tyrosine phosphorylation of phospholipase C gamma-1 following IRS-2 association in human monocytes: relationship with the inhibitory effect of IL-13 on ROI production.	IRS2 PLCG1	3.33e-06	2	64	2	9535722
Pubmed	Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates.	TBX21 ARID1A	3.33e-06	2	64	2	37315534
Pubmed	Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.	GDI1 GDI2	3.33e-06	2	64	2	7585614
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HEG1 CELSR2 L1CAM LAMA5 LAMC3 IRS2 PLCG1 ARID1A MMP17 RYR1 ARHGAP33	5.04e-06	1105	64	11	35748872
Pubmed	Increased CD34+CD38 -CD123 + cells in myelodysplastic syndrome displaying malignant features similar to those in AML.	CD34 IL3RA	9.99e-06	3	64	2	24846193
Pubmed	RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.	GDI1 GDI2	9.99e-06	3	64	2	26240314
Pubmed	Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport.	GDI1 GDI2	9.99e-06	3	64	2	7543319
Pubmed	Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.	PANK2 PANK3	9.99e-06	3	64	2	17379144
Pubmed	Overexpression of IL-3Rα on CD34+CD38- stem cells defines leukemia-initiating cells in Fanconi anemia AML.	CD34 IL3RA	9.99e-06	3	64	2	21330473
Pubmed	Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.	GDI1 GDI2	9.99e-06	3	64	2	7513052
Pubmed	High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.	CD34 IL3RA	9.99e-06	3	64	2	21933861
Pubmed	Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.	PANK2 PANK3	9.99e-06	3	64	2	17631502
Pubmed	Compartmentalization of mammalian pantothenate kinases.	PANK2 PANK3	9.99e-06	3	64	2	23152917
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	PDIA4 CERS5 GAK HEG1 GOPC CELSR2 AXL LOXL1 LAMA5 UQCRC1 SLFN5 ARID1A	1.17e-05	1451	64	12	30550785
Pubmed	A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.	PANK2 PANK3	2.00e-05	4	64	2	11479594
Pubmed	Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.	PANK2 PANK3	2.00e-05	4	64	2	22815849
Pubmed	Coenzyme A metabolism.	PANK2 PANK3	2.00e-05	4	64	2	2981478
Pubmed	Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo.	GOPC MAP1A	2.00e-05	4	64	2	15136571
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PDIA4 USP24 UQCRC1 ARID1A GDI1 GDI2 NIPBL SON	2.60e-05	653	64	8	22586326
Pubmed	Quantitative analyses of CD7, CD33, CD34, CD56, and CD123 within the FLT3-ITD/NPM1-MUT myeloblastic/monocytic bulk AML blastic populations.	CD34 IL3RA	3.32e-05	5	64	2	34034609
Pubmed	GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.	GDI1 GDI2	3.32e-05	5	64	2	19570034
Pubmed	The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.	AXL TBX21	3.32e-05	5	64	2	18840707
Pubmed	Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.	LAMA5 LAMC3	3.32e-05	5	64	2	16581764
Pubmed	A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia.	CD34 IL3RA	3.32e-05	5	64	2	25957287
Pubmed	Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.	GDI1 GDI2	3.32e-05	5	64	2	11929610
Pubmed	Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3).	LAMA5 LAMC3	3.32e-05	5	64	2	11964076
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FCSK DNASE2B GOPC MAP1A BCAS2 IRS2 ARID1A ADCY6 ARHGAP33 SON	3.49e-05	1116	64	10	31753913
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	LOXL1 LAMA5 LTBP2 EMILIN1	3.72e-05	101	64	4	20551380
Pubmed	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.	GDI1 GDI2	4.98e-05	6	64	2	11809807
Pubmed	Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.	AXL PLCG1	6.96e-05	7	64	2	9178760
Pubmed	Structured RNAs in the ENCODE selected regions of the human genome.	GDI1 SON	9.27e-05	8	64	2	17568003
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	GOPC USP24 KIRREL1 PLCG1	1.09e-04	133	64	4	15144186
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDIA4 PANK2 BCAS2 ALS2 IRS2 UQCRC1 EDEM1 GDI1 QRICH2 SON	1.12e-04	1284	64	10	17353931
Pubmed	Mitochondrial localization and function of a subset of 22q11 deletion syndrome candidate genes.	UQCRC1 TANGO2	1.19e-04	9	64	2	18775783
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	PDIA4 GAK GOPC BCAS2 L1CAM USP24 LAMA5 LAMC3 UQCRC1 NIPBL	1.22e-04	1297	64	10	33545068
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA5 LAMC3	1.49e-04	10	64	2	11784026
Pubmed	Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees.	L1CAM GDI1	1.49e-04	10	64	2	12777533
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LOXL1 LAMA5 LTBP2 EMILIN1	1.56e-04	146	64	4	27068509
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	AXL USP24 IRS2 ARID1A GDI1 NIPBL RYR1	1.70e-04	638	64	7	31182584
Pubmed	Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.	CD34 LAMA5	1.81e-04	11	64	2	11435469
Pubmed	CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.	AXL TBX21	1.81e-04	11	64	2	37572655
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA5 LAMC3	1.81e-04	11	64	2	21524702
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA5 LAMC3	1.81e-04	11	64	2	23472759
Pubmed	Tag1 deficiency results in olfactory dysfunction through impaired migration of mitral cells.	TBX21 L1CAM	2.57e-04	13	64	2	26525675
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	LOXL1 LAMA5 LTBP2 EMILIN1	2.60e-04	167	64	4	22159717
Pubmed	Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo.	CD34 EMILIN1	2.99e-04	14	64	2	31475747
Pubmed	Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model.	L1CAM PLCG1	2.99e-04	14	64	2	21339379
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LOXL1 LAMA5 LTBP2 EMILIN1	3.11e-04	175	64	4	28071719
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA5 LAMC3	3.45e-04	15	64	2	15895400
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CELSR2 LTBP2 PLCG1 IL3RA RYR1	3.55e-04	329	64	5	17474147
Pubmed	Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.	L1CAM IRX6	3.93e-04	16	64	2	15647317
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA5 LAMC3	3.93e-04	16	64	2	17601529
Pubmed	Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.	CELSR2 PCSK9	3.93e-04	16	64	2	19198609
Pubmed	Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.	CELSR2 PCSK9	3.93e-04	16	64	2	20691829
Pubmed	Modifier genes and protective alleles in humans and mice.	MAP1A ALS2	3.93e-04	16	64	2	12787792
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	LAMA5 LAMC3 EMILIN1	4.25e-04	79	64	3	18757743
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	PDIA4 USP24 PLCG1 GDI1 SON	4.35e-04	344	64	5	30333137
Pubmed	Arx homeobox gene is essential for development of mouse olfactory system.	TBX21 L1CAM	4.45e-04	17	64	2	15677725
Pubmed	A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.	CELSR2 PCSK9	5.00e-04	18	64	2	20971364
Pubmed	Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.	TBX21 L1CAM	5.00e-04	18	64	2	27320921
Pubmed	Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.	USP24 PCSK9	5.00e-04	18	64	2	23726366
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA5 LAMC3	5.00e-04	18	64	2	11311202
Pubmed	Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.	MAP1A L1CAM UQCRC1	5.09e-04	84	64	3	19165527
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	PANK2 CELSR2 BCAS2 IRS2 SON	5.21e-04	358	64	5	32460013
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	LOXL1 LTBP2 EMILIN1	5.45e-04	86	64	3	28327460
Pubmed	Additive effect of multiple genetic variants on the risk of coronary artery disease.	CELSR2 PCSK9	5.59e-04	19	64	2	20738937
Pubmed	Genes, plasticity and mental retardation.	L1CAM GDI1	5.59e-04	19	64	2	18329113
Pubmed	EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning.	PDIA4 EDEM1	5.59e-04	19	64	2	33671632
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA5 LAMC3	6.20e-04	20	64	2	22911573
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	AXL LAMA5 IRS2 RYR1	6.63e-04	214	64	4	22199357
Pubmed	Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity.	L1CAM ARID1A	6.84e-04	21	64	2	34011608
Pubmed	Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells.	CD34 IL3RA	6.84e-04	21	64	2	8499630
Pubmed	Schwann cell myelination requires integration of laminin activities.	LAMA5 LAMC3	6.84e-04	21	64	2	22767514
Pubmed	Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.	CD34 IL3RA	7.52e-04	22	64	2	9324354
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	LAMC3 CSMD3	7.52e-04	22	64	2	35245678
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	L1CAM LAMA5 LTBP2	7.75e-04	97	64	3	27559042
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	MAP1A SRCIN1 UQCRC1 GDI1 GDI2	8.87e-04	403	64	5	30562941
Pubmed	Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells.	CD34 L1CAM	8.96e-04	24	64	2	30348676
Pubmed	c-IAP1 binds and processes PCSK9 protein: linking the c-IAP1 in a TNF-α pathway to PCSK9-mediated LDLR degradation pathway.	PDIA4 PCSK9	8.96e-04	24	64	2	23085658
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HEG1 PARP14 CEMIP	9.22e-04	103	64	3	10574462
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	KIRREL1 IRS2 PLCG1	9.22e-04	103	64	3	21706016
Pubmed	A chemical tool for blue light-inducible proximity photo-crosslinking in live cells.	USP24 FBXO7	9.73e-04	25	64	2	35211260
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMA5 LAMC3	1.05e-03	26	64	2	24742657
Pubmed	Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism†.	IRS2 EDEM1	1.14e-03	27	64	2	35377412
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	LOXL1 LTBP2 EMILIN1 PCSK9	1.15e-03	248	64	4	24006456
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CERS5 GAK MAP1A L1CAM SRCIN1 UQCRC1 ARID1A GDI1 GDI2	1.18e-03	1431	64	9	37142655
Pubmed	Endosomal Rab cycles regulate Parkin-mediated mitophagy.	GDI1 GDI2	1.22e-03	28	64	2	29360040
Pubmed	A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.	MAP1A LOXL1	1.31e-03	29	64	2	8617512
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	CELSR2 PCSK9	1.31e-03	29	64	2	20167577
Pubmed	D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.	PDIA4 EDEM1	1.50e-03	31	64	2	22925884
Pubmed	SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.	IRS2 PLCG1	1.60e-03	32	64	2	22974441
Pubmed	Genetic variations in humans associated with differences in the course of hepatitis C.	CD34 LTBP2	1.60e-03	32	64	2	15063762
Pubmed	Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.	CELSR2 PCSK9	1.70e-03	33	64	2	18193044
Pubmed	Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients.	CD34 LTBP2	1.70e-03	33	64	2	19817957
Pubmed	Genetic mapping of the human and mouse phospholipase C genes.	MAP1A PLCG1	1.70e-03	33	64	2	8672127
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	MAP1A PIP5KL1 SRCIN1 GDI2	1.81e-03	281	64	4	28706196
Interaction	CBLN4 interactions	PDIA4 CELSR2 L1CAM LAMA5 PCSK9 CEMIP	3.09e-06	127	64	6	int:CBLN4
Interaction	LAIR2 interactions	PDIA4 LAMA5 VSIG8 EMILIN1	1.76e-05	49	64	4	int:LAIR2
Cytoband	2q37.3	ERFE RTP5 ANKMY1	1.76e-04	77	64	3	2q37.3
GeneFamily	Laminin subunits	LAMA5 LAMC3	3.59e-04	12	43	2	626
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	PDIA4 CERS5 HEG1 ZBTB39 AXL CD34 PTDSS2 LTBP2 ARID1A ADCY6 SON	7.15e-07	681	64	11	M5314
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	PDIA4 CERS5 HEG1 ZBTB39 AXL CD34 PTDSS2 LTBP2 ARID1A ADCY6 SON	9.76e-07	703	64	11	MM1055
Coexpression	GAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS	HEG1 AXL CD34 LAMA5 KIRREL1 LAMC3 LTBP2 CSMD3 EMILIN1	3.66e-06	505	64	9	M39167
Coexpression	LEF1_UP.V1_UP	AXL LOXL1 L1CAM SLC35G2 LTBP2 RYR1	7.98e-06	194	64	6	M2905
Coexpression	GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN	SHD UBXN11 TBX21 L1CAM SLFN5 ADCY6	9.50e-06	200	64	6	M6570
Coexpression	MULLIGHAN_NPM1_SIGNATURE_3_DN	HEG1 CD34 PLCG1 GDI2 RYR1	4.68e-05	161	64	5	M15047
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	ERFE LOXL1 TBX21 LTBP2 IRX6 PCSK9	5.35e-05	272	64	6	M1938
Coexpression	MCCABE_HOXC6_TARGETS_CANCER_UP	VPS11 L1CAM ARHGAP33	5.94e-05	31	64	3	M15456
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	ERFE LOXL1 TBX21 LTBP2 IRX6 PCSK9	6.53e-05	282	64	6	MM822
Coexpression	IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR	VPS11 HEG1 GOPC MAP1A CD34 ALS2 EMILIN1	1.25e-04	458	64	7	M1606
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP	HEG1 PLCG1 GDI2 IL3RA CEMIP	1.27e-04	199	64	5	M7656
Coexpression	GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP	HEG1 DYRK4 EDEM1 GDI2 IL3RA	1.27e-04	199	64	5	M7652
Coexpression	GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_UP	BCAS2 PIP5KL1 KIRREL1 PLCG1 IRX6	1.27e-04	199	64	5	M7067
Coexpression	GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_DN	UBXN11 AXL TBX21 L1CAM ADCY6	1.27e-04	199	64	5	M6576
Coexpression	GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP	DNASE2B UBXN11 FBXO7 UQCRC1 DYRK4	1.27e-04	199	64	5	M7118
Coexpression	GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_UP	FCSK L1CAM IRS2 PLCG1 GDI1	1.30e-04	200	64	5	M9748
Coexpression	GSE27786_LSK_VS_NKCELL_DN	CERS5 GAK AXL SON CEMIP	1.30e-04	200	64	5	M4753
Coexpression	IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR	VPS11 HEG1 GOPC MAP1A CD34 ALS2 EMILIN1	1.73e-04	483	64	7	MM1012
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LOXL1 KIRREL1 LAMC3 LTBP2 EMILIN1 CEMIP	1.12e-07	159	64	6	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	SHD RTP5 MAP1A SLC35G2 IL3RA EMILIN1	1.67e-07	170	64	6	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LOXL1 LAMC3 LTBP2 EMILIN1 CEMIP	4.00e-06	165	64	5	570483b43ccb5831feec9337b4664814431d40b1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LOXL1 LAMC3 LTBP2 EMILIN1 CEMIP	4.00e-06	165	64	5	2026a9a07f4d314cc05c167e491312b373468e46
ToppCell	PCW_10-12-Neuronal-Neuronal_postreplicative\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SHD CELSR2 L1CAM SRCIN1 MMP17	6.27e-06	181	64	5	1aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCell	PCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SHD CELSR2 L1CAM SRCIN1 MMP17	6.27e-06	181	64	5	6aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCell	PCW_10-12-Neuronal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SHD CELSR2 L1CAM SRCIN1 MMP17	6.27e-06	181	64	5	381b553e2cae65ce6be100662a5f9f963353840c
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHD CELSR2 L1CAM SRCIN1 MMP17	6.44e-06	182	64	5	d6740bca2b974122b8451989365a94a81140afd1
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEG1 CD34 SLFN5 PARP14 DISP1	7.35e-06	187	64	5	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LOXL1 LAMC3 LTBP2 EMILIN1 CEMIP	8.56e-06	193	64	5	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LOXL1 LAMC3 LTBP2 EMILIN1 CEMIP	8.56e-06	193	64	5	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HEG1 AXL LOXL1 CD34 DISP1	8.78e-06	194	64	5	7b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell	343B-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PDIA4 MAP1A LOXL1 CD34 GDI2	9.93e-06	199	64	5	08c7e631b2e203dd7dcb75a7f9377d292bc5a0fd
ToppCell	343B-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PDIA4 MAP1A LOXL1 CD34 GDI2	9.93e-06	199	64	5	4338bf6cafc26c5d6497955d91914f84bacfacfa
ToppCell	343B-Fibroblasts-Fibroblast-F\|343B / Donor, Lineage, Cell class and subclass (all cells)	MAP1A AXL LOXL1 CD34 EMILIN1	9.93e-06	199	64	5	b877c1d24357249781032e99d4237f72789cc9b8
ToppCell	343B-Fibroblasts-Fibroblast-F-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MAP1A AXL LOXL1 CD34 EMILIN1	9.93e-06	199	64	5	e32fa66f3361474088ba1dd58574822537950d59
ToppCell	3'-Adult-LymphNode-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HEG1 CD34 LAMA5 SLC35G2 IL3RA	1.02e-05	200	64	5	663e2b4672f193844bb9bf4873749114977c19b3
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LAMC3 LTBP2 QRICH2 PCSK9	4.28e-05	135	64	4	5b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LOXL1 LAMC3 LTBP2 EMILIN1	6.45e-05	150	64	4	7a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LOXL1 LAMC3 LTBP2 EMILIN1	6.45e-05	150	64	4	e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	LOXL1 LAMC3 LTBP2 EMILIN1	6.97e-05	153	64	4	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	LOXL1 LAMC3 LTBP2 EMILIN1	6.97e-05	153	64	4	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	LOXL1 LAMC3 LTBP2 EMILIN1	6.97e-05	153	64	4	2513edfae62a44e51d3556675a096723194c966c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA5 KIRREL1 SRCIN1 IRX6	7.89e-05	158	64	4	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA5 KIRREL1 SRCIN1 IRX6	7.89e-05	158	64	4	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-tDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SHD MAP1A AXL IL3RA	8.09e-05	159	64	4	141c3ed35c7d11fcaec4acd9cb37104cc259db25
ToppCell	severe_COVID-19-pDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	SHD AXL IL3RA RYR1	8.09e-05	159	64	4	ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell	facs-Brain_Myeloid-Cerebellum_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL SLFN5 PARP14 IL3RA	8.49e-05	161	64	4	5c762609531a7c5505aa5637abf8e0311568d7fd
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL SLFN5 PARP14 IL3RA	8.49e-05	161	64	4	b14a83ad07a7acb07c766aa862b527698976b6fc
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL SLFN5 PARP14 IL3RA	8.49e-05	161	64	4	c5d9d47dcedfbb1ac77f4afaf860ae4d9f26fd3f
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL SLFN5 PARP14 IL3RA	8.49e-05	161	64	4	26c0d876339bfd34d9a43af5b9fb08f50526f2c9
ToppCell	Influenza_Severe-pDC\|World / Disease group and Cell class	SHD MAP1A PIP5KL1 IL3RA	9.56e-05	166	64	4	bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	USP24 ANKMY1 ARID1A SON	9.56e-05	166	64	4	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|World / disease group, cell group and cell class (v2)	SHD MAP1A AXL IL3RA	9.78e-05	167	64	4	bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCell	droplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 L1CAM ALS2 PLCG1	9.78e-05	167	64	4	bad33497ceeab968a7eb8a48b921c6f936390743
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 PIP5KL1 EMILIN1 SON	9.78e-05	167	64	4	b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	SHD AXL KIRREL1 EMILIN1	1.00e-04	168	64	4	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	SHD MAP1A AXL IL3RA	1.00e-04	168	64	4	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	SHD MAP1A AXL IL3RA	1.05e-04	170	64	4	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SHD MAP1A AXL IL3RA	1.07e-04	171	64	4	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SHD MAP1A AXL IL3RA	1.07e-04	171	64	4	debbb071d260639b16269c94d172766908325c58
ToppCell	ICU-SEP-Myeloid-pDC\|ICU-SEP / Disease, Lineage and Cell Type	SHD MAP1A AXL IL3RA	1.07e-04	171	64	4	72c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHD L1CAM SRCIN1 MMP17	1.10e-04	172	64	4	bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERFE CSMD3 EMILIN1 CEMIP	1.15e-04	174	64	4	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	10x5'-blood-Myeloid_Dendritic\|blood / Manually curated celltypes from each tissue	SHD CFAP77 AXL IL3RA	1.17e-04	175	64	4	1c48eec300d5a6d4a810947b995af3b8c0a5a601
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DXO IP6K3 LAMC3 DISP1	1.17e-04	175	64	4	3031f1eef3cfef8a7e5f57e567cb0868d06cac38
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	SHD MAP1A IL3RA EMILIN1	1.17e-04	175	64	4	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	3'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IP6K3 AXL LOXL1 LAMA5	1.20e-04	176	64	4	56e19240f4a7b617a986e3c0854b757394e78251
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	SHD MAP1A IL3RA EMILIN1	1.20e-04	176	64	4	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	IP6K3 LOXL1 LTBP2 EMILIN1	1.20e-04	176	64	4	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	3'-Adult-LymphNode-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IP6K3 AXL LOXL1 LAMA5	1.20e-04	176	64	4	c88b46fe29ae7606c8880a6ff0ebb85c0dfda8bd
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	IP6K3 LOXL1 LTBP2 EMILIN1	1.20e-04	176	64	4	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC35G2 LTBP2 IL3RA CEMIP	1.22e-04	177	64	4	76f5df101c693e5fa61554244d877fc8169ee66f
ToppCell	wk_15-18-Epithelial-PNS-Schwann_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SHD CELSR2 L1CAM MMP17	1.22e-04	177	64	4	5357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP77 CD34 SLC35G2 IL3RA	1.25e-04	178	64	4	aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNASE2B LAMA5 IL3RA DISP1	1.25e-04	178	64	4	cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNASE2B L1CAM LAMA5 IL3RA	1.25e-04	178	64	4	41745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNASE2B L1CAM LAMA5 IL3RA	1.25e-04	178	64	4	eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHD ANKMY1 PTDSS2 MMP17	1.31e-04	180	64	4	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PDIA4 DXO DYRK4 QRICH2	1.31e-04	180	64	4	8e96f8646c002768b272359af485dc0ab57e0ccd
ToppCell	390C-Fibroblasts-Fibroblast-G\|390C / Donor, Lineage, Cell class and subclass (all cells)	IP6K3 LOXL1 LTBP2 EMILIN1	1.31e-04	180	64	4	137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell	droplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A LOXL1 CSMD3 MMP17	1.31e-04	180	64	4	b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell	390C-Fibroblasts-Fibroblast-G-\|390C / Donor, Lineage, Cell class and subclass (all cells)	IP6K3 LOXL1 LTBP2 EMILIN1	1.31e-04	180	64	4	cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1A LAMC3 MMP17 EMILIN1	1.33e-04	181	64	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1A LAMC3 MMP17 EMILIN1	1.33e-04	181	64	4	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SHD L1CAM SRCIN1 MMP17	1.36e-04	182	64	4	b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRCIN1 CSMD3 MMP17 ARHGAP33	1.36e-04	182	64	4	a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell	healthy_donor-Myeloid-Monocytic-SC_&_Eosinophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MAP1A CD34 IL3RA ADCY6	1.36e-04	182	64	4	6bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1A L1CAM MMP17 CEMIP	1.36e-04	182	64	4	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SHD CELSR2 L1CAM MMP17	1.39e-04	183	64	4	e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 LAMC3 EMILIN1 ADCY6	1.42e-04	184	64	4	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 LAMC3 EMILIN1 ADCY6	1.42e-04	184	64	4	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	URO-Myeloid-pDC\|URO / Disease, Lineage and Cell Type	PDIA4 SHD MAP1A IL3RA	1.42e-04	184	64	4	0edb5dd003c2bca0b9e3ec18d03610d68bd52538
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM FBXO7 CSMD3 MMP17	1.42e-04	184	64	4	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 CD34 LAMC3 IRX6	1.42e-04	184	64	4	fe4d3def3da4ffdea5ae6bb059f5397efd58fef3
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 CD34 SLFN5 EMILIN1	1.45e-04	185	64	4	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 CD34 SLFN5 EMILIN1	1.45e-04	185	64	4	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LOXL1 CD34 SLFN5 EMILIN1	1.45e-04	185	64	4	a94694e226856bc5b168464f52d76004145717a5
ToppCell	Leuk-UTI-Other-RBC\|Leuk-UTI / Disease, Lineage and Cell Type	PDIA4 SHD MAP1A IL3RA	1.45e-04	185	64	4	5b5dd856d6efc0539d92533cff134bbc3f98be45
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A LOXL1 LAMC3 EMILIN1	1.45e-04	185	64	4	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A LOXL1 LAMC3 EMILIN1	1.45e-04	185	64	4	049d793d043d5d434f143025de49dd210d18756c
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A LOXL1 LAMC3 EMILIN1	1.45e-04	185	64	4	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SHD L1CAM SRCIN1 MMP17	1.45e-04	185	64	4	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SHD L1CAM SRCIN1 MMP17	1.45e-04	185	64	4	a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCell	Leuk-UTI-Other\|Leuk-UTI / Disease, Lineage and Cell Type	PDIA4 SHD MAP1A IL3RA	1.45e-04	185	64	4	895e8087e97ac0eab3446385e6e0dd24bea7f42c
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM FBXO7 CSMD3 MMP17	1.48e-04	186	64	4	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SHD L1CAM SRCIN1 MMP17	1.48e-04	186	64	4	3113c85d0ac5fc46532c19b1bb71f34b985e1276
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1A AXL LAMC3 EMILIN1	1.48e-04	186	64	4	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	droplet-Heart-HEART-1m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM FBXO7 SRCIN1 MMP17	1.48e-04	186	64	4	fddc6b93f98b10aaf8d4ebc142b46d8213f3129d
ToppCell	Control-Fibroblasts-Pathological_FB\|Control / group, cell type (main and fine annotations)	MAP1A LOXL1 LTBP2 EMILIN1	1.51e-04	187	64	4	b7280b8baa0fba9c2b4bff660c240ed96f6ff9b7
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	AXL LOXL1 CD34 LTBP2	1.51e-04	187	64	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	PCW_05-06-Neuronal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SHD L1CAM SRCIN1 MMP17	1.51e-04	187	64	4	03a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 AXL LOXL1 CD34	1.51e-04	187	64	4	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM FBXO7 CSMD3 MMP17	1.51e-04	187	64	4	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM FBXO7 CSMD3 MMP17	1.51e-04	187	64	4	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEG1 CD34 SLFN5 PARP14	1.51e-04	187	64	4	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	HEG1 AXL LOXL1 LTBP2	1.51e-04	187	64	4	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IP6K3 CD34 SLFN5 EMILIN1	1.54e-04	188	64	4	51c6796a9488c056a10d048082015342c2e037f9
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IP6K3 CD34 SLFN5 EMILIN1	1.54e-04	188	64	4	b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HEG1 AXL LOXL1 CD34	1.54e-04	188	64	4	aa516273cdde53c8c0295f06830972388f890c97
Disease	pantothenate kinase-associated neurodegeneration (implicated_via_orthology)	PANK2 PANK3	2.68e-05	4	63	2	DOID:3981 (implicated_via_orthology)
Disease	sleep duration, low density lipoprotein cholesterol measurement	CELSR2 USP24 PLCG1 PCSK9	4.39e-05	91	63	4	EFO_0004611, EFO_0005271
Disease	apolipoprotein A 1 measurement, apolipoprotein B measurement	CELSR2 SLC35G2 ARID1A PCSK9	8.26e-05	107	63	4	EFO_0004614, EFO_0004615
Disease	LDL cholesterol change measurement	CELSR2 PCSK9	9.36e-05	7	63	2	EFO_0007804
Disease	cholesterol in small VLDL measurement	CELSR2 SLC35G2 PCSK9	2.01e-04	53	63	3	EFO_0022228
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	L1CAM ARID1A CSMD3 RYR1	2.88e-04	148	63	4	C0279702
Disease	response to statin, LDL cholesterol change measurement	CELSR2 PCSK9	4.63e-04	15	63	2	EFO_0007804, GO_0036273
Disease	apolipoprotein B measurement	CELSR2 TBX21 USP24 SLC35G2 PLCG1 ARID1A PCSK9	5.21e-04	663	63	7	EFO_0004615
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	DXO VPS11 CELSR2 ARID1A PCSK9	5.45e-04	312	63	5	EFO_0004612, EFO_0010351
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	DXO VPS11 CELSR2 ARID1A PCSK9	5.69e-04	315	63	5	EFO_0004574, EFO_0004612
Disease	level of Sphingomyelin (d34:1) in blood serum	USP24 PCSK9	6.71e-04	18	63	2	OBA_2045175
Disease	lipid measurement, high density lipoprotein cholesterol measurement	DXO CELSR2 MAP1A ARID1A PCSK9	7.02e-04	330	63	5	EFO_0004529, EFO_0004612
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 L1CAM	7.49e-04	19	63	2	DOID:10908 (implicated_via_orthology)
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	CELSR2 PCSK9	9.18e-04	21	63	2	EFO_0022246
Disease	platelet crit	VPS11 MAP1A IP6K3 LAMA5 IRS2 UQCRC1 TANGO2 ARID1A	9.18e-04	952	63	8	EFO_0007985
Disease	Granulomatous Slack Skin	PLCG1 ARID1A	1.01e-03	22	63	2	C0376407
Disease	proprotein convertase subtilisin/kexin type 9 measurement	USP24 PCSK9	1.01e-03	22	63	2	EFO_0009312
Disease	Lymphoma, T-Cell, Cutaneous	PLCG1 ARID1A	1.10e-03	23	63	2	C0079773
Disease	clinical and behavioural ideal cardiovascular health	CELSR2 PCSK9	1.10e-03	23	63	2	EFO_0007654
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	CELSR2 PLCG1 ARID1A PCSK9	1.17e-03	215	63	4	EFO_0008317, EFO_0008591
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	CELSR2 ARID1A PCSK9	1.26e-03	99	63	3	EFO_0004611, EFO_0007878
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	CELSR2 PLCG1 ARID1A PCSK9	1.27e-03	220	63	4	EFO_0004529, EFO_0008317
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	CELSR2 MAP1A ARID1A PCSK9	1.36e-03	224	63	4	EFO_0004574, EFO_0008317
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	CELSR2 ARID1A PCSK9	1.37e-03	102	63	3	EFO_0004329, EFO_0004611
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	CELSR2 PLCG1 ARID1A PCSK9	1.38e-03	225	63	4	EFO_0008317, EFO_0010351
Disease	level of Sterol ester (27:1/16:0) in blood serum	USP24 PCSK9	1.41e-03	26	63	2	OBA_2045191
Disease	phospholipids:total lipids ratio	CELSR2 USP24 ARID1A PCSK9	1.42e-03	227	63	4	EFO_0020946
Disease	Sezary Syndrome	PLCG1 ARID1A	1.52e-03	27	63	2	C0036920
Disease	familial hyperlipidemia	CELSR2 ARID1A PCSK9	1.53e-03	106	63	3	MONDO_0001336
Disease	monocyte count	DXO UBXN11 PIP5KL1 KIRREL1 IRS2 VSIG8 GDI2 DISP1 RYR1	1.87e-03	1320	63	9	EFO_0005091
Disease	level of Sphingomyelin (d38:1) in blood serum	USP24 PCSK9	1.88e-03	30	63	2	OBA_2045180
Disease	antihyperlipidemic drug use measurement	CELSR2 ARID1A PCSK9	1.93e-03	115	63	3	EFO_0803367

Protein segments in the cluster

Peptide	Gene	Start	Entry
YGLYIRGLDGGVPEA	CFAP77	121	Q6ZQR2
PGIPANGLRYGDDYV	CSMD3	3176	Q7Z407
FRNGLEDGYGEYRIP	ALS2	1076	Q96Q42
LQYLNGDYEVEPGRG	ADCY6	521	O43306
LAVGLDPEGYGNPDF	CELSR2	2496	Q9HCU4
GRADEGIQPDPYYGL	CEMIP	126	Q8WUJ3
DERGGYDPPTYIRDL	CEMIP	566	Q8WUJ3
DLEGPADGYGYPRGR	CERS5	31	Q8N5B7
YGVAYRLAPDPDREG	DISP1	1056	Q96F81
DQYGLRQPGAYQPGL	QRICH2	801	Q9H0J4
RPELGAALGIYGAPY	IRX6	61	P78412
YRLYLDELEGGGNPG	GOPC	391	Q9HD26
YGGPYDRVRTEPGIG	ARID1A	1281	O14497
YPLYGLGELPQGFAR	GDI2	226	P50395
EEDYQAALGPGGPYL	PIP5KL1	116	Q5T9C9
ELEGGPYSPLGKDYR	MAP1A	1896	P78559
EYGGGEELPEYPPQG	LOXL1	236	Q08397
YRADEYQPPDGGSLV	PCSK9	166	Q8NBP7
VYYLPDAEGAFRRGP	ERFE	226	Q4G0M1
QYDPVYRLDPHGGGL	NIPBL	1351	Q6KC79
YSGEDYPQAIPELEG	L1CAM	806	P32004
LERNGLYPAYTGLPG	HEG1	1341	Q9ULI3
DLELADAYYLGGVPP	LAMA5	3056	O15230
DGPDPGYIFGLENLI	IP6K3	386	Q96PC2
VAGYGPIEQLPDYNR	UQCRC1	456	P31930
NGPGPNFDLRDGYPD	DXO	76	O77932
RDIYGGDYERFGLPG	PANK3	251	Q9H999
RDIYGGDYERFGLPG	PANK2	451	Q9BZ23
PYNGGGRVANVEYFP	PARP14	251	Q460N5
PGEYINIDFGEPGAR	IRS2	916	Q9Y4H2
PAPLDRGENLYYEIG	ARHGAP33	1076	O14559
PPELGQGDADVAGYL	FCSK	286	Q8N0W3
EYDQPYGGFLDILRG	GAK	366	O14976
ELYTGYPLFPGENEV	DYRK4	296	Q9NR20
VGPGAPADVQYDLYL	IL3RA	126	P26951
IPEEGYDYPPTGRRN	DNASE2B	151	Q8WZ79
GEYDQRPTLPYVGDP	FBXO7	446	Q9Y3I1
ADQRFGPGVETYPDG	ANKMY1	76	Q9P2S6
GYVLGGRGRGPDEYE	EDEM1	101	Q92611
FRPGYEYGPGPDDLH	LTBP2	1651	Q14767
LYADYRAPGPARFDG	KIRREL1	621	Q96J84
YPLYGLGELPQGFAR	GDI1	226	P31150
RVLLNDGGYYDPETG	EMILIN1	891	Q9Y6C2
LGYGYNIEPPDQEPS	RYR1	1046	P21817
GERLGEDPYYTENGG	CD34	321	P28906
YGDGPGPARHPREAY	RTP5	126	Q14D33
LPGRGVQLYDTPYEE	SHD	136	Q96IW2
QGPVGDPLRYGLPYE	MMP17	271	Q9ULZ9
PQPGDDGYEEINEGY	SLC35G2	31	Q8TBE7
REDPIGAGALYDYGR	MT-ND6	136	P03923
PERDYGGNCLIYDPD	PTDSS2	166	Q9BVG9
GRPYDYNGPREKYGI	PDIA4	261	P13667
LPYFDQGYEAPGVRE	BCAS2	16	O75934
YVLDPEDYGPNGLDI	VSIG8	46	P0DPA2
GDECVYLYQPDERGP	VPS11	251	Q9H270
DAEYPREYRTLGGGG	SRCIN1	21	Q9C0H9
GYVGLEGLPYFLEEP	AXL	131	P30530
TAEPDYGALYEGRNP	PLCG1	766	P19174
GGGDYLGADRNYVLP	ZBTB39	161	O15060
LTNERPGLDYGGYEP	USP24	41	Q9UPU5
GYNYERHGVGLDVPP	SLFN5	66	Q08AF3
AYRLGQDPYRLGHDP	SON	941	P18583
PADAEGYQPGEGYAA	TBX21	96	Q9UL17
GYQPGEGYAAPDPRA	TBX21	101	Q9UL17
EGYAAPDPRAGLYPG	TBX21	106	Q9UL17
GLYPGPREDYALPAG	TBX21	116	Q9UL17
GDVICYYGNRGEPDP	TANGO2	131	Q6ICL3
QVYLEDGLDPFPGEG	UBXN11	291	Q5T124
YGRPEGQYLRPGEDE	LAMC3	171	Q9Y6N6