Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1B10 AKR1B15

1.09e-044862GO:0047718
GeneOntologyMolecularFunctionallyl-alcohol dehydrogenase activity

AKR1B10 AKR1B15

1.09e-044862GO:0047655
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1B10 AKR1B15

2.72e-046862GO:0045550
GeneOntologyMolecularFunctiondouble-stranded DNA 3'-5' DNA exonuclease activity

TREX1 RAD1

2.72e-046862GO:0008311
GeneOntologyMolecularFunctiondouble-stranded DNA exodeoxyribonuclease activity

TREX1 RAD1

5.05e-048862GO:0008309
GeneOntologyMolecularFunctionNADP+ binding

AKR1B10 AKR1B15

6.47e-049862GO:0070401
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

TREX1 SGIP1 EP400 RBBP8 RAD1 REV3L

9.43e-04262866GO:0140097
DomainSEA

TMPRSS15 ADGRF5 MUC12

1.27e-0422843PF01390
DomainSEA

TMPRSS15 ADGRF5 MUC12

1.46e-0423843PS50024
DomainSEA_dom

TMPRSS15 ADGRF5 MUC12

1.46e-0423843IPR000082
DomainALDOKETO_REDUCTASE_1

AKR1B10 AKR1B15

8.79e-0410842PS00798
DomainAldo/ket_reductase_CS

AKR1B10 AKR1B15

8.79e-0410842IPR018170
DomainAldo/keto_reductase

AKR1B10 AKR1B15

8.79e-0410842IPR020471
DomainRap_GAP

RAP1GAP SIPA1L1

8.79e-0410842PF02145
DomainALDOKETO_REDUCTASE_2

AKR1B10 AKR1B15

8.79e-0410842PS00062
DomainALDOKETO_REDUCTASE_3

AKR1B10 AKR1B15

8.79e-0410842PS00063
DomainRap_GAP_dom

RAP1GAP SIPA1L1

1.07e-0311842IPR000331
DomainRAPGAP

RAP1GAP SIPA1L1

1.07e-0311842PS50085
Domain-

TREX1 GIN1 REV3L

1.23e-03478433.30.420.10
DomainSEA

TMPRSS15 ADGRF5

1.76e-0314842SM00200
Domain-

TMPRSS15 ADGRF5

2.02e-03158423.30.70.960
Domain-

AKR1B10 AKR1B15

2.30e-03168423.20.20.100
DomainNADP_OxRdtase_dom

AKR1B10 AKR1B15

2.60e-0317842IPR023210
DomainAldo_ket_red

AKR1B10 AKR1B15

2.60e-0317842PF00248
DomainAldo/ket_red/Kv-b

AKR1B10 AKR1B15

2.60e-0317842IPR001395
DomainSOCS

RAB40AL RAB40A

3.60e-0320842SM00253
DomainRNaseH-like_dom

TREX1 GIN1 REV3L

3.71e-0369843IPR012337
DomainEPHD

KMT2C MLLT6

4.36e-0322842PS51805
DomainPentatricopeptide_repeat

DENND4C HTT

4.76e-0323842IPR002885
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TRERF1 PRUNE2 UBN1 MAP1A EP400 MLLT6 NUP214 HRNR BSN C6orf132

1.29e-07430871035044719
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAGI1 ABLIM1 KRT8 STIM2 RAP1GAP HIVEP2 PPFIA1 SIPA1L1 RAI14 ARHGAP21 USP6NL DENND4C C6orf132

2.27e-07861871336931259
Pubmed

Interaction network of human early embryonic transcription factors.

TRERF1 RLF KMT2C HIVEP2 EP400 EPC1 GATA4 NUP214 HRNR

2.52e-0735187938297188
Pubmed

A human MAP kinase interactome.

MAGI1 KMT2C ABLIM1 KRT8 HIVEP2 SF3B1 MAP1A SIMC1 NUP214 MUC12

3.96e-07486871020936779
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TRERF1 RLF RBBP8 PPFIA1 RAI14 ZDBF2 NUP214 ARHGAP21 DENND4C

1.08e-0641887934709266
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ZSWIM8 CEP85 UBN1 MAP1A EP400 RBBP8 TPRN ZDBF2 AASDH BSN

2.20e-06588871038580884
Pubmed

Human transcription factor protein interaction networks.

TRERF1 RLF KMT2C CEP85 UBN1 EP400 GLI3 EPC1 GATA4 MLLT6 RAI14 NUP214 HRNR TBR1 VDAC3

2.43e-061429871535140242
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HIVEP3 KMT2C HIVEP2 UBN1 EP400 TRAPPC12 LAMA5 MLLT6 NUP214 REV3L ARHGAP21 HTT C6orf132

3.63e-061105871335748872
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

KRT8 SF3B1 RAI14 ZDBF2 NUP214 DENND4C EFR3A

3.82e-0625687733397691
Pubmed

Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse.

AKR1B10 AKR1B15

6.19e-06287234954342
Pubmed

Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.

AKR1B10 AKR1B15

6.19e-06287225120755
Pubmed

Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.

AKR1B10 AKR1B15

6.19e-06287221087085
Pubmed

Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland.

AKR1B10 AKR1B15

6.19e-0628728526877
Pubmed

AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity.

AKR1B10 AKR1B15

6.19e-06287236518763
Pubmed

Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.

HIVEP3 HIVEP2

6.19e-06287220404140
Pubmed

1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.

AKR1B10 AKR1B15

6.19e-0628727578036
Pubmed

Characterization of the promoter of the gene for a mouse vas deferens protein related to the aldo-keto reductase superfamily: effect of steroid hormones and phorbol esters.

AKR1B10 AKR1B15

6.19e-0628728541228
Pubmed

Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice.

AKR1B10 AKR1B15

6.19e-06287233644071
Pubmed

Huntingtin is associated with cytomatrix proteins at the presynaptic terminal.

BSN HTT

6.19e-06287225461618
Pubmed

Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.

HIVEP3 HIVEP2

6.19e-0628722247438
Pubmed

Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.

AKR1B10 AKR1B15

6.19e-06287225538260
Pubmed

Functional expression of novel human and murine AKR1B genes.

AKR1B10 AKR1B15

6.19e-06287221276782
Pubmed

Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.

AKR1B10 AKR1B15

6.19e-06287231911858
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

MAGI1 KMT2C ABLIM1 UBN1 TRAPPC12 TPRN RNF19B GATA4 MLLT6 TBR1

8.86e-06689871036543142
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

SIPA1L1 MTSS1 LRRTM2 BSN

9.02e-06528749455477
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

MAGI1 ABLIM1 STIM2 PPFIA1 RAI14 NUP214 ARHGAP21 USP6NL DENND4C EFR3A

1.12e-05708871039231216
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GJA1 ABLIM1 RAP1GAP SGIP1 SF3B1 MAP1A PPFIA1 SIPA1L1 VCAN AKR1B10 RAI14 BSN ARHGAP21 VDAC3

1.22e-051431871437142655
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

MAGI1 ABLIM1 RAI14 NUP214 ARHGAP21 USP6NL DENND4C C6orf132 EFR3A

1.23e-0556587925468996
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MAP1A PPFIA1 SIPA1L1 ZDBF2 ARHGAP21 DENND4C

1.48e-0520987636779422
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

MAGI1 HIVEP2 EML5 MTSS1 DENND4C

1.81e-0512887525332235
Pubmed

Uncommon somatic mutations in metastatic NUT midline carcinoma.

KMT2C SF3B1

1.85e-05387228967088
Pubmed

Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database.

HIVEP3 TBR1

1.85e-05387225849321
Pubmed

Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.

AKR1B10 AKR1B15

1.85e-05387217381426
Pubmed

Overexpression of circFNDC3B promotes the progression of oral tongue squamous cell carcinoma through the miR-1322/MED1 axis.

FNDC3B MED1

1.85e-05387235916453
Pubmed

A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase.

AKR1B10 AKR1B15

1.85e-0538727510692
Pubmed

Dampening of death pathways by schnurri-2 is essential for T-cell development.

HIVEP3 HIVEP2

1.85e-05387221475200
Pubmed

Identification of risk loci for Crohn's disease phenotypes using a genome-wide association study.

MAGI1 LY75

1.85e-05387225557950
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

ABLIM1 CEP85 MICALL2 SIPA1L1 BSN VDAC3

1.87e-0521887633378226
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

FNDC3B KMT2C ABLIM1 EP400 MICALL2 PPFIA1 SIPA1L1 LAMA5 RAI14 MED1 USP6NL C6orf132 VDAC3 EFR3A

2.01e-051497871431527615
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 EML5 MAP1A EP400 GLI3 TPRN PPFIA1 SIPA1L1 EPC1 GATA4 REV3L BRWD1

2.17e-051116871231753913
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

ABLIM1 SGIP1 MAP1A SIPA1L1 BSN BRWD1

2.59e-0523187616452087
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

HIVEP2 SF3B1 EML5 GLI3 SIPA1L1 DENND4C

2.66e-0523287625515538
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

GJA1 ABLIM1 SGIP1 MAP1A SIPA1L1 BSN HTT

2.73e-0534787717114649
Pubmed

Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.

AKR1B10 AKR1B15

3.70e-05487221179467
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ABLIM1 STIM2 GLI3 ARHGAP21 USP6NL C6orf132

5.34e-0526387634702444
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KMT2C EP400 MTSS1 LAMA5 RAI14 BSN USP6NL EFR3A

5.54e-0552987814621295
Pubmed

Differential expression of N-CAM, vimentin and MAP1B during initial pathfinding of olfactory receptor neurons in the mouse embryo.

KRT8 MAP1A

6.16e-0558728651505
Pubmed

Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes.

AKR1B10 AKR1B15

6.16e-05587210092857
Pubmed

An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract.

GJA1 GATA4

6.16e-05587237772400
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40AL RAB40A

6.16e-05587227909076
Pubmed

Dynamics of global gene expression changes during mouse preimplantation development.

GJA1 KRT8

6.16e-05587214723852
Pubmed

Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice.

AKR1B10 AKR1B15

6.16e-05587226291391
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZSWIM8 ABLIM1 RAP1GAP CEP85 HIVEP2 SF3B1 SIPA1L1 RAI14 BTBD2 REV3L ARHGAP21 BRWD1

8.46e-051285871235914814
Pubmed

Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus.

RLF MAP1A HTT

8.55e-053487325505242
Pubmed

Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis.

TBR1 HTT

9.22e-05687220696378
Pubmed

Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

KRT8 LAMA5

9.22e-05687215668394
Pubmed

Counter-Balance Between Gli3 and miR-7 Is Required for Proper Morphogenesis and Size Control of the Mouse Brain.

GLI3 TBR1

9.22e-05687230210296
Pubmed

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.

ABLIM1 KRT8 SF3B1 SIPA1L1 AKR1B10 NUP214

1.00e-0429587626209609
Pubmed

Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.

SF3B1 RBBP8 HRNR

1.02e-043687324147044
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CEP85 UBN1 MAP1A SIPA1L1 HRNR

1.02e-0418487532908313
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

MAGI1 SGIP1 SIPA1L1 VCAN RAI14 ARHGAP21 VDAC3

1.05e-0443087732581705
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

ABLIM1 SF3B1 UBN1 MAP1A EP400 SIMC1 MED1

1.28e-0444487734795231
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

MAGI1 ABLIM1 SIPA1L1 ARHGAP21

1.29e-0410287415778465
Pubmed

Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.

GATA4 MED1

1.29e-04787211724781
Pubmed

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43).

GJA1 FNDC1

1.29e-04787219723622
Pubmed

Comparison of the number of triplets in SCA1, MJD/SCA3, HD, SBMA, DRPLA, MD, FRAXA and FRDA genes in schizophrenic patients and a healthy population.

FXN HTT

1.29e-04787211121205
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 ABLIM1 SF3B1 UBN1 EP400 RBBP8 SIPA1L1 NUP214 MED1

1.40e-0477487915302935
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

STIM2 LIPE SF3B1 EP400 GLI3 PPFIA1 RAI14 HRNR ARHGAP21

1.44e-0477787935844135
Pubmed

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart.

GJA1 GATA4

1.72e-04887218568026
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

ABLIM1 CEP85 MAP1A EP400 MED1 ARHGAP21 VDAC3

1.86e-0447287738943005
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

B3GALT1 TREX1 ABLIM1 STIM2 CEP85 TRAPPC12 TPRN SIPA1L1 USP6NL

2.03e-0481487923251661
Pubmed

Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation.

KRT8 LAMA5

2.20e-04987215102706
Pubmed

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.

KRT8 GLI3

2.20e-04987225083987
Pubmed

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.

KRT8 LAMA5

2.20e-04987230456378
Pubmed

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.

GLI3 TBR1

2.20e-04987211748155
Pubmed

Hdac6 regulates Tip60-p400 function in stem cells.

SF3B1 EP400 EPC1

2.41e-044887324302573
Pubmed

Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries.

KRT8 LAMA5

2.75e-041087222911783
Pubmed

Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.

AASDH ACSF2

2.75e-041087217762044
Pubmed

Generation of a conditionally null allele of the laminin alpha1 gene.

GATA4 LAMA5

2.75e-041087216100707
Pubmed

A role for primary cilia in aortic valve development and disease.

GLI3 VCAN

2.75e-041087228556366
Pubmed

Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing.

SF3B1 GATA4

2.75e-041087231794640
Pubmed

Ectopic expression of GATA6 bypasses requirement for Grb2 in primitive endoderm formation.

KRT8 GATA4

2.75e-041087220925113
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KMT2C SF3B1 GLI3 RAI14 BSN

3.06e-0423387537704626
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

SF3B1 RBBP8 SIPA1L1 VCAN TBR1

3.18e-0423587530258100
Pubmed

Proteomic analysis of in vivo phosphorylated synaptic proteins.

ABLIM1 SGIP1 BSN

3.24e-045387315572359
Pubmed

Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis.

KRT8 LAMA5

3.35e-041187233515576
Pubmed

Gli3 is required for maintenance and fate specification of cortical progenitors.

GLI3 TBR1

3.35e-041187221525285
Pubmed

Meis1 is required for the maintenance of postnatal thymic epithelial cells.

KRT8 LY75

3.35e-041187224594519
Pubmed

TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis.

RAI14 TBR1

3.35e-041187229305158
Pubmed

The highly conserved and multifunctional NuA4 HAT complex.

EP400 EPC1

3.35e-041187215196461
Pubmed

Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43.

GJA1 LAMA5

3.35e-041187227899284
Pubmed

DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis.

GLI3 GATA4

4.02e-041287219211672
Pubmed

Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.

REV3L BSN

4.02e-041287228700933
Pubmed

Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation.

GLI3 GATA4

4.02e-041287219325248
Pubmed

Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart.

GJA1 GATA4

4.02e-041287217050624
Pubmed

Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning.

KRT8 GLI3

4.02e-041287219445942
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

KRT8 LAMA5

4.02e-041287216750824
Pubmed

Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression.

GLI3 TBR1

4.02e-041287230093555
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2C ABLIM1 CEP85 EP400 RAI14 MED1 HTT

4.62e-0454987738280479
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

RLF KMT2C CEP85 UBN1 GLI3 EPC1 ZDBF2 NUP214 MUC12 MED1 HTT

4.71e-041327871132694731
InteractionYWHAZ interactions

GJA1 FNDC3B ABLIM1 KRT8 STIM2 RAP1GAP HIVEP2 SF3B1 PPFIA1 SIPA1L1 SIMC1 RAI14 HRNR SUCO ARHGAP21 USP6NL DENND4C HTT C6orf132 SMTNL2

6.27e-0713198720int:YWHAZ
InteractionYWHAH interactions

MAGI1 ABLIM1 KRT8 STIM2 RAP1GAP HIVEP2 PPFIA1 SIPA1L1 RAI14 MED1 SUCO ARHGAP21 USP6NL DENND4C HTT C6orf132 SMTNL2

4.04e-0611028717int:YWHAH
InteractionYWHAG interactions

MAGI1 ABLIM1 KRT8 STIM2 RAP1GAP HIVEP2 PPFIA1 SIPA1L1 SIMC1 GATA4 RAI14 SUCO ARHGAP21 USP6NL DENND4C HTT C6orf132 SMTNL2

5.14e-0612488718int:YWHAG
InteractionFLOT1 interactions

MAGI1 ABLIM1 EP400 PPFIA1 HASPIN GATA4 RAI14 ARHGAP21 USP6NL HTT EFR3A

6.20e-064758711int:FLOT1
InteractionSFN interactions

MAGI1 ABLIM1 KRT8 RAP1GAP MAP1A PPFIA1 SIPA1L1 ARHGAP21 USP6NL DENND4C HTT C6orf132 SMTNL2

8.14e-066928713int:SFN
InteractionBCAN interactions

VCAN LAMA5 ZDBF2 HTT

1.72e-0536874int:BCAN
InteractionYWHAQ interactions

GJA1 ABLIM1 KRT8 RAP1GAP HIVEP2 PPFIA1 SIPA1L1 RAI14 MED1 SUCO ARHGAP21 USP6NL DENND4C HTT C6orf132 SMTNL2

2.06e-0511188716int:YWHAQ
InteractionPTPRD interactions

ABLIM1 SLCO4C1 PPFIA1 MTSS1 LRRTM2 SMTNL2

2.21e-05131876int:PTPRD
InteractionYWHAB interactions

MAGI1 ABLIM1 KRT8 STIM2 RAP1GAP PPFIA1 SIPA1L1 RAI14 SUCO ARHGAP21 USP6NL DENND4C HTT C6orf132 SMTNL2

2.65e-0510148715int:YWHAB
InteractionRHOB interactions

MAGI1 GJA1 ABLIM1 STIM2 SGIP1 MAP1A LRP10 PPFIA1 SIPA1L1 RAI14 ARHGAP21 USP6NL EFR3A

6.16e-058408713int:RHOB
InteractionKCNA3 interactions

MAGI1 KMT2C ABLIM1 STIM2 PPFIA1 SIPA1L1 RAI14 NUP214 BSN ARHGAP21 USP6NL DENND4C EFR3A

8.88e-058718713int:KCNA3
InteractionPHLPP1 interactions

KRT8 SF3B1 RAI14 ZDBF2 NUP214 DENND4C SMTNL2 EFR3A

9.61e-05333878int:PHLPP1
InteractionCRX interactions

TRERF1 RLF KMT2C EP400 EPC1 GATA4 MLLT6

1.15e-04254877int:CRX
InteractionPHF21A interactions

RLF RBBP8 PPFIA1 RAI14 ZDBF2 NUP214 ARHGAP21 DENND4C

1.18e-04343878int:PHF21A
InteractionPRNP interactions

MAGI1 GJA1 KMT2C ABLIM1 SGIP1 UBN1 TRAPPC12 TPRN RNF19B HASPIN GATA4 MLLT6 FXN TBR1 BSN

1.19e-0411588715int:PRNP
Cytoband7q33

AKR1B10 AKR1B15 CCDC136

6.65e-05418737q33
Cytoband2q24

TBR1 LY75

1.93e-04118722q24
CoexpressionAIZARANI_LIVER_C7_EPCAM_POS_BILE_DUCT_CELLS_2

MAGI1 ABLIM1 KRT8 RAP1GAP LRP10 VCAN LAMA5 C6orf132

6.93e-07219878M39111
CoexpressionGSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN

HIVEP3 KMT2C STIM2 HIVEP2 SF3B1 SIPA1L1 ZDBF2

4.73e-06200877M3510
CoexpressionVERHAAK_GLIOBLASTOMA_CLASSICAL

B3GALT1 GJA1 LRP10 SIPA1L1 BTBD2 ZNF235

1.64e-05161876M2121
CoexpressionGSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP

TRERF1 ABLIM1 LIPE SIPA1L1 MTSS1 ACSF2

2.30e-05171876M6316
CoexpressionDESCARTES_FETAL_SPLEEN_MESOTHELIAL_CELLS

B3GALT1 GJA1 KRT8 SGIP1 LAMA5 SMTNL2

4.67e-05194876M40292
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000

MAGI1 GJA1 FNDC3B RBBP8 VCAN AKR1B10 RNF19B SIMC1 LRRTM2 GATA4 REV3L SUCO ARHGAP21 SMTNL2 VDAC3

1.04e-068378515gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

B3GALT1 GJA1 SGIP1 MICALL2 GLI3 VCAN RAI14 NUP214 REV3L LY75 SUCO C6orf132

5.44e-057698512gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500

MAGI1 KRT8 RBBP8 GLI3 VCAN AKR1B10 RNF19B GATA4 ZDBF2

5.77e-05432859gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500

MAGI1 RBBP8 VCAN AKR1B10 RNF19B GATA4 REV3L ARHGAP21 VDAC3

5.77e-05432859gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

B3GALT1 GJA1 SGIP1 MICALL2 GLI3 VCAN RAI14 LY75

1.34e-04377858gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500

VCAN RNF19B GATA4 REV3L VDAC3

1.36e-04123855gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_500
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 FNDC3B ABLIM1 SGIP1 RBBP8 VCAN C6orf132

1.05e-0719387780e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 FNDC3B ABLIM1 SGIP1 RBBP8 VCAN C6orf132

1.05e-07193877b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 PRUNE2 GJA1 FNDC1 MAP1A ADGRF5

1.82e-06187876e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellfacs-Heart-RV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 GJA1 ABLIM1 LIPE APLNR ADGRF5

2.05e-0619187684ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B ABLIM1 SGIP1 RBBP8 VCAN C6orf132

2.18e-06193876263d185af6ed80e639f864e4966268e0862c61dc
ToppCellnormal_Pleural_Fluid-Epithelial_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

MAGI1 GJA1 KRT8 LAMA5 RAI14 C6orf132

2.60e-06199876564ba7acd03be2d6e4d0850cb2c7237a788dc275
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 CEP85 EML5 NIPAL2 LAMA5

1.51e-0515987524f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

MAGI1 ABLIM1 LAMA5 ADGRF5 RAI14

2.09e-05170875e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MAGI1 GJA1 ABLIM1 KRT8 LAMA5

2.53e-051778753128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellwk_15-18-Mesenchymal-Mesothelial-intermediate_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FNDC1 TMPRSS15 AKR1B10 GATA4 AKR1B15

2.67e-05179875b1f085e4c8d65d5cdbfaf2db80343638abb08979
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

GJA1 ABLIM1 TPRN LAMA5 ADGRF5

2.75e-051808752d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RUBCNL EPC1 LAMA5 FCRL5 USP6NL

2.82e-05181875768d14c452192f92fa557ae59e84c43436f575f0
ToppCellE18.5-samps|World / Age Group, Lineage, Cell class and subclass

GJA1 KRT8 SLCO4C1 LAMA5 MED1

2.90e-051828759649f15858d1ede73e068afc59df3ac367b49687
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 LIPE APLNR MTSS1 ADGRF5

2.90e-0518287581279877b920b5a1bc991a07d3031d6458700fe3
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGI1 GJA1 ABLIM1 APLNR ADGRF5

2.90e-05182875840427d1c23d60482c943ff006b14007ed44d247
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

MAGI1 GJA1 KRT8 LAMA5 ADGRF5

2.97e-0518387531fef35ecf30162662f24d335d8f0cceacc07039
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

MAGI1 GJA1 KRT8 LAMA5 ADGRF5

2.97e-05183875c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 FNDC1 SGIP1 MAP1A VCAN

3.13e-05185875ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

MAGI1 KRT8 RAI14 MUC4 C6orf132

3.21e-05186875d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KRT8 VCAN RUBCNL MTSS1 RAI14

3.21e-05186875f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KRT8 VCAN RUBCNL MTSS1 RAI14

3.21e-051868758694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

MAGI1 GJA1 KRT8 LAMA5 ADGRF5

3.30e-05187875fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellwk_15-18-Mesenchymal-Mesothelial-Late_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GJA1 KRT8 FNDC1 AKR1B10 GATA4

3.38e-0518887538a53f99f1876359983936403aefca93281d10fd
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GJA1 KRT8 GATA4 LAMA5 SMTNL2

3.38e-051888756151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 FNDC3B ABLIM1 SGIP1 RBBP8

3.56e-05190875bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 GJA1 LIPE APLNR ADGRF5

3.56e-0519087589d1d686cc683206534e2157554d7d0df5d53497
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 FNDC3B ABLIM1 SGIP1 RBBP8

3.56e-05190875b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 GJA1 LIPE APLNR ADGRF5

3.56e-0519087565ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCellIPF-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

MAGI1 GJA1 ABLIM1 SGIP1 RAI14

3.56e-05190875ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 LIPE APLNR LAMA5 ADGRF5

3.65e-05191875a0018f88f7132477cc467ee15db029a585290595
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

MAGI1 KRT8 ADGRF5 RAI14 MUC4

3.65e-05191875c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GJA1 KRT8 AKR1B10 GATA4 SMTNL2

3.65e-05191875b5374674312ff5803a1d369f5533027532344679
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT8 RAP1GAP SLCO4C1 RAI14 C6orf132

3.65e-05191875c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

MAGI1 GJA1 ABLIM1 KRT8 LAMA5

3.65e-0519187566875b2ec2c510489407f3e433a90cdf74a15094
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

MAGI1 KRT8 ADGRF5 RAI14 MUC4

3.65e-051918753c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellfacs-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT8 RAP1GAP SLCO4C1 RAI14 C6orf132

3.65e-051918755f43f98cfe7a08d61ed55f34808fabfe47f1ac2e
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 LIPE APLNR LAMA5 ADGRF5

3.65e-051918756b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 LIPE APLNR LAMA5 ADGRF5

3.65e-0519187590f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

MAGI1 GJA1 ABLIM1 SGIP1 RAI14

3.74e-051928752496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

STIM2 SIPA1L1 RUBCNL MTSS1 FCRL5

3.74e-05192875446c61c0d6ba89c619efe87ee495951299953981
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

MAGI1 KRT8 ADGRF5 MUC4 C6orf132

3.74e-05192875d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

3.74e-0519287513e4b17d7a592604140777aca235f795df6b3f91
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SIAE RAP1GAP SLCO4C1 ADGRF5 RAI14

3.74e-05192875cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

MAGI1 SIAE RAP1GAP SLCO4C1 ADGRF5

3.74e-0519287506013a07e3a873b1d1c0451643c528593ac32a9c
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

3.74e-051928756244541688f85917018a057aa0b3e5972934dfbc
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAB40AL LRRTM2 HRNR BSN VDAC3

3.83e-05193875088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCellIPF-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MAGI1 GJA1 ABLIM1 APLNR RAI14

3.83e-05193875ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 GJA1 ABLIM1 NIPAL2 SMTNL2

3.93e-05194875a3adcdc8b87332e8beb9bcd70cf36424af10633d
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

MAGI1 GJA1 ABLIM1 ADGRF5 RAI14

3.93e-051948759591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNDC3B VCAN RUBCNL RNF19B MTSS1

3.93e-051948753ef9e88e66f2f2ae95dcc834ea605c40c60783fc
ToppCellIPF-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

MAGI1 GJA1 ABLIM1 APLNR RAI14

4.02e-05195875120296531bbc8080dcabacbd64733cc1dc34603a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

STIM2 SIPA1L1 RUBCNL MTSS1 USP6NL

4.02e-05195875481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

STIM2 SIPA1L1 RUBCNL MTSS1 USP6NL

4.02e-051958756108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GJA1 KRT8 RAP1GAP ADGRF5 RAI14

4.02e-0519587543164511f32e4591cb5399182fbac0b911716233
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAGI1 GJA1 RAP1GAP SLCO4C1 ADGRF5

4.02e-05195875d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCellPND01-Epithelial-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GJA1 KRT8 RAP1GAP ADGRF5 RAI14

4.02e-051958759337111d75a487abc02969337718c30b1fe81379
ToppCellwk_08-11-Mesenchymal-Mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GJA1 KRT8 FNDC1 GATA4 SMTNL2

4.02e-051958759016a44b521214546a55a822ebdef5b5312206d2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAGI1 GJA1 APLNR ADGRF5 RAI14

4.12e-05196875629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT8 TPRN LAMA5 MUC4 C6orf132

4.12e-051968759554ac6eb5f381bcde3ba40c32aa3fc340974540
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABLIM1 KRT8 STIM2 AKR1B10 MUC4

4.22e-051978755c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell5'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIAE KRT8 RNF19B MUC12 MUC4

4.22e-0519787582e83b4e4f54f9aa3a4a7bbf48b6dd603adeb69b
ToppCell5'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIAE KRT8 RNF19B MUC12 MUC4

4.22e-051978758f894a4f0d34289f19d227788466b9fb4be15d54
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RBBP8 GLI3 MTSS1 LAMA5 MUC4

4.33e-051988755374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RBBP8 GLI3 MTSS1 LAMA5 MUC4

4.43e-0519987594a7867e800df352731796de8c24cba133c29622
ToppCelltumor_Lung-Epithelial_cells-tS2|tumor_Lung / Location, Cell class and cell subclass

KRT8 ADGRF5 RAI14 MUC4 C6orf132

4.43e-0519987528ec59e01061287fb0892491790b316e2b93e232
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MAGI1 GJA1 APLNR ADGRF5 RAI14

4.43e-0519987597052c28e354833901f28d339b09f97f50a5b752
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HIVEP3 FNDC3B MICALL2 VCAN REV3L

4.43e-051998758b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-052008753c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GJA1 ABLIM1 MICALL2 GLI3

4.54e-05200875d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GJA1 ABLIM1 MICALL2 GLI3

4.54e-05200875f861509b54185d89931db64da1b9d81986cc7938
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-05200875c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-05200875c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellNasal_Brush-Epithelial|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ABLIM1 KRT8 STIM2 LRP10 MUC4

4.54e-052008757911073119ee47a37b68b73fc54f063e902a5067
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-0520087565c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-0520087540e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellBiopsy_Other_PF-Epithelial-Transitional_AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

GJA1 KRT8 TPRN LAMA5 ADGRF5

4.54e-052008751ba6327851aa61e9a1f1fe1671bc27929d93ac74
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-052008753ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellILEUM-non-inflamed-(7)_CD36+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MAGI1 GJA1 APLNR ADGRF5 RAI14

4.54e-0520087545755a597725015dc3ee36f9166f9e82f6f9c603
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-05200875ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GJA1 ABLIM1 MICALL2 GLI3

4.54e-0520087516f468217427921fa18c6d078ffa990eb019b257
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-0520087535c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MAGI1 GJA1 APLNR ADGRF5 RAI14

4.54e-05200875ec92fe4eafe527d351ee73c9735e96855ac506a3
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GJA1 ABLIM1 MICALL2 GLI3

4.54e-052008750442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

B3GALT1 GJA1 ABLIM1 MICALL2 GLI3

4.54e-0520087501819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

KRT8 RAP1GAP SLCO4C1 ADGRF5 RAI14

4.54e-052008759970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 GJA1 ABLIM1 LAMA5 RAI14

4.54e-05200875a3b09580738783c6bff31ea33d5188912e56b8a7
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

STIM2 SIPA1L1 RUBCNL MTSS1

6.44e-05110874bc1986e5a496a4d25da3445b6f252f81741619f4
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-mesenchymal_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

EML5 LRRTM2 GATA4 TBR1

9.32e-05121874176de42c088988fe1a7838f96add26ee8a30e543
ToppCellmild_COVID-19-B_cell|mild_COVID-19 / disease group, cell group and cell class (v2)

GLI3 SIPA1L1 RUBCNL FCRL5

1.30e-041328744b372483bc106aecc7b96a09131e1695e54e7dc4
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

GJA1 FNDC1 ADGRF5 RAI14

2.36e-04154874511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HIVEP2 GLI3 VCAN RNF19B

2.41e-04155874cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

TRERF1 GJA1 RNF19B MTSS1

2.47e-04156874ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCelldroplet-Heart-nan-3m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIPE MTSS1 NUP214 AASDH

2.54e-04157874d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCell368C-Myeloid-Dendritic-cDC1|368C / Donor, Lineage, Cell class and subclass (all cells)

LIPE RUBCNL HRNR ACSF2

2.60e-04158874c276a259e20ee704e2d04baf693e8d677f96f654
ToppCell368C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LIPE RUBCNL HRNR ACSF2

2.79e-041618741011094c54381d52566e24c92f89f2efc2aa3eea
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LIPE RUBCNL HRNR ACSF2

2.92e-04163874299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT8 MICALL2 LRRTM2 RAI14

2.99e-04164874c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

FNDC1 VCAN RAI14 BSN

2.99e-041648749b4a6007abae992db871d9f6f731d5af724de30d
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT8 MICALL2 LRRTM2 RAI14

2.99e-0416487476b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT8 MICALL2 LRRTM2 RAI14

2.99e-04164874911081739174ec68bc0893c804e4276b206bea7d
DiseaseATRIOVENTRICULAR CANAL DEFECT

GJA1 GATA4

2.40e-053842C1389016
DiseaseAtrioventricular Septal Defect

GJA1 GATA4

2.40e-053842C1389018
Diseasetestosterone measurement

B3GALT1 MAGI1 LIPE MAP1A TRAPPC12 TPRN APLNR GATA4 AKR1B15 RAB40A ARHGAP21 BRWD1

2.56e-0412758412EFO_0004908
Diseasesymmetrical dimethylarginine measurement

AKR1B10 AKR1B15

2.85e-049842EFO_0006523
Diseaseplatelet component distribution width

PRUNE2 HIVEP2 EPC1 MTSS1 GATA4 LAMA5 ADGRF5 BTBD2 BRWD1

2.98e-04755849EFO_0007984
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

SLCO4C1 GIN1

4.33e-0411842EFO_0801871
Diseaseheart rate

GJA1 FNDC3B SIPA1L1 ARHGAP21 C6orf132

4.67e-04225845EFO_0004326
Diseasesialate O-acetylesterase measurement

SIAE BTBD2

5.19e-0412842EFO_0803073
Diseaseneutrophil count

TRERF1 HIVEP3 PRUNE2 MAGI1 HIVEP2 SGIP1 LRP10 RBBP8 ADGRF5 FCRL5 LY75 HTT

5.29e-0413828412EFO_0004833
Diseasesalicylurate measurement

B3GALT1 ABLIM1

6.12e-0413842EFO_0010532
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP3 HIVEP2

6.12e-0413842DOID:0050787 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

TRERF1 GJA1 FNDC3B KRT8 RAP1GAP LIPE TRAPPC12 SIPA1L1 NUP214 FCRL5

9.42e-0410748410C0006142
Diseaseskin hydration measurement

ABLIM1 ARHGAP21

1.62e-0321842EFO_0009586
Diseasecytokine measurement

MAGI1 SLCO4C1 GIN1 RBBP8 FCRL5 ARHGAP21

2.05e-03461846EFO_0004873
Diseasehypertrophic cardiomyopathy

FNDC3B KMT2C CCDC136

2.33e-0392843EFO_0000538
DiseaseNeurodevelopmental Disorders

HIVEP3 KMT2C TBR1

2.40e-0393843C1535926

Protein segments in the cluster

PeptideGeneStartEntry
FSTSGHAYTDTGKAS

VDAC3

41

Q9Y277
EAGPAHSYTSSSESP

EP400

1796

Q96L91
SGVYKGLHLSSTTPT

EPC1

691

Q9H2F5
DYKSPHVTGSGASAG

MLLT6

426

P55198
SSPLTIYSGSEASGH

VCAN

2826

P13611
AKAHGTSSYTPDKSS

RBBP8

236

Q99708
SHIPSSKTASLPGYG

ABLIM1

646

O14639
TRPTSSYTGSKPFSH

B3GALT1

26

Q9Y5Z6
HSKGITVTAYSPLGS

AKR1B10

201

O60218
TTGSPKGATLSHYNI

ACSF2

266

Q96CM8
PTFDKSSTTVYIGSH

AASDH

776

Q4L235
SPSGTLTITSGHAQY

EFR3A

791

Q14156
SYHSTQTDLGPSLGK

RAI14

386

Q9P0K7
SPYSHLGGIDYKTTT

RAB40A

41

Q8WXH6
SPYSHLGGIDYKTTT

RAB40AL

41

P0C0E4
SVGSASPHGSSEKSS

RUBCNL

111

Q9H714
STFGNAGSSHLDYPK

RAD1

191

O60671
IHTKTTSGYAGGLSS

KRT8

411

P05787
EKSASYSSGHSQGPG

APLNR

341

P35414
SGTLGHPGSLDETTY

FXN

81

Q16595
TTYSSHSTTLPKTTG

MUC4

546

Q99102
SSSSYHVGDKEIPTT

LRRTM2

386

O43300
SGSYGHLSASAISPA

GLI3

331

P10071
PPTSNGLSGYKDSSH

KMT2C

4171

Q8NEZ4
GVFSSPGYTHLASVS

LRP10

201

Q7Z4F1
STQVSHIGPGTYSSK

LEXM

61

Q3ZCV2
HIGPGTYSSKETCFS

LEXM

66

Q3ZCV2
SSFSHSTPSGNGKYL

MAP1A

1291

P78559
QETYDSPASHSSKTG

MAGI1

586

Q96QZ7
YSSAPGGTTIHTASA

KIAA2026

1841

Q5HYC2
LTGSSGSFQATHYPK

TMPRSS15

231

P98073
PSAYSGEKLSSHDFS

BSN

3446

Q9UPA5
TLHSGAYKATGEPGT

MICALL2

221

Q8IY33
YHEDVTLGSSSAPSG

FCRL5

601

Q96RD9
SHYSLSSESHVGPTG

MTSS1

351

O43312
YPGTGSKSDHGTSQA

FAM214A

301

Q32MH5
SRGPYESGSSHSSGL

HRNR

1506

Q86YZ3
PSTSGKRSSDGSLSH

PPFIA1

231

Q13136
ASDTCHSYGGTLPSV

LY75

976

O60449
TGEPPSYSSGSDSSK

NUP214

496

P35658
TLFVGGLPASSHSSK

LAMA5

3466

O15230
YTTGTPKATSSHQGL

NUTM1

956

Q86Y26
GKKHTTTPSTSLYAT

C6orf132

16

Q5T0Z8
TEPGLSSHYGHSSSV

GATA4

366

P43694
TSKSSSLGSFYHLPS

HTT

1221

P42858
SGSATEYTFTHLKPG

FNDC3B

626

Q53EP0
STGADTHPQGKYSSL

FNDC1

931

Q4ZHG4
KYPTEGISHVTSPSS

CEP85

6

Q6P2H3
KGKSDPYHATSGALS

GJA1

241

P17302
SSSSGDVGKLHYPTG

DENND4C

1436

Q5VZ89
SSRTAYLGTHKTSAG

BRWD1

1481

Q9NSI6
YLGTHKTSAGISSGV

BRWD1

1486

Q9NSI6
HYTLNGKSSTIPSCG

HASPIN

666

Q8TF76
SPGSGKYLAVASHDS

EML5

1091

Q05BV3
TACATLKGPDSHYGT

BTBD2

466

Q9BX70
KPSSHSQYTSSGSVS

MED1

1076

Q15648
MSGYSGTSPHEKTSA

LIPE

271

Q05469
GHVGLPSVSYASSGA

PAOX

106

Q6QHF9
TKHTSGLSYGQESGP

RNF19B

266

Q6ZMZ0
KFLNVSSSYPHSGGS

TBR1

16

Q16650
SLSSPETGKYSEHSG

PRUNE2

1636

Q8WUY3
LSYGTLPDGSDSTKS

NIPAL2

361

Q9H841
TGEYHSTTLPSERSG

GIN1

21

Q9NXP7
SSSGTPHKRDSFIYS

RAP1GAP

596

P47736
SGIDTTSYGPSHGST

SIPA1L1

1326

O43166
TSYGPSHGSTASLGA

SIPA1L1

1331

O43166
SSGTGILKASSSHPS

SIMC1

636

Q8NDZ2
GSIPYDSVTGPSKHS

SIAE

241

Q9HAT2
SFPSDTSTHTFGAGK

SIX6OS1

536

Q8N1H7
HSKGITVTAYSPLGS

AKR1B15

201

C9JRZ8
GDYKVTFHTGSSSLP

ADGRF5

596

Q8IZF2
KSSEPSGSLGLSDYS

CCDC136

206

Q96JN2
HGSTLSVSASPEKSY

USP6NL

671

Q92738
HSPKAYSGGRSSSSN

RBMXL3

361

Q8N7X1
KYPGSLSSTVHSENS

REV3L

626

O60673
ITHGSFSGSLQGYPS

RLF

1076

Q13129
YGKSGLLTSHTTDSL

TRAPPC12

411

Q8WVT3
AHNSGLPSLTSSLYS

STIM2

446

Q9P246
EEPGSTKGKHFYSSS

SGIP1

91

Q9BQI5
DSVPTHKSSLYIGTG

SLCO4C1

256

Q6ZQN7
SSSTSLLGQKKPGYH

SF3B1

71

O75533
LSPGSKGSTESGYFS

HIVEP3

381

Q5T1R4
SGSKTSLDSGVPHYS

ZDBF2

996

Q9HCK1
SGYGAVTASKHSNSP

SMTNL2

256

Q2TAL5
SSYKGPPSEGSSETS

SUCO

1156

Q9UBS9
KAGGNSSTSIFTHPS

ZSWIM8

1251

A7E2V4
PEGSSGLSSYTPKHS

TPRN

651

Q4KMQ1
PAKPHSVSSAGSSYK

UBN1

886

Q9NPG3
NLLSPHSKGSTDSGY

HIVEP2

386

P31629
PSGILLKSGNYSGHS

ARHGAP21

341

Q5T5U3
SSPSEHGPRKSYSLG

TREX1

166

Q9NSU2
PACSTHEKDTSYSSG

ZNF235

291

Q14590
QSGYCSVKSSPSHST

TRERF1

1061

Q96PN7
GPESTTFHSSPGYTK

MUC12

361

Q9UKN1
SGLVEESTAYHSSPG

MUC12

1906

Q9UKN1
SGLVEESTTYHSSPG

MUC12

4546

Q9UKN1