Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

1.60e-0835465GO:0015020
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 GTDC1

8.54e-06211466GO:0016758
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in AV node cell action potential

CACNA1C CACNB2

1.56e-053462GO:0086056
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

2.63e-05153465GO:0008194
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 GTDC1

4.93e-05288466GO:0016757
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNB2

5.17e-055462GO:0086007
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1C CACNB2

4.64e-0414462GO:0008331
GeneOntologyMolecularFunctionATP-dependent activity

DHX16 DHX33 DNAH12 KIF13A MYO7A DDX60 NLRP3

4.74e-04614467GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

DHX16 DHX33 DNAH12 KIF13A DDX60 NLRP3

4.97e-04441466GO:0016887
GeneOntologyMolecularFunctionRNA helicase activity

DHX16 DHX33 DDX60

7.71e-0478463GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DHX16 DHX33 DDX60

8.30e-0480463GO:0008186
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DHX16 DHX33 DNAH12 KIF13A DDX60 NLRP3 GSPT1

1.85e-03775467GO:0017111
GeneOntologyMolecularFunctionretinoic acid binding

UGT2B4 UGT2B7

1.89e-0328462GO:0001972
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH12 KIF13A MYO7A

2.54e-03118463GO:0003774
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

DHX16 METTL1 DHX33 GTDC1 DDX60

2.63e-03417465GO:0140098
GeneOntologyMolecularFunctionpyrophosphatase activity

DHX16 DHX33 DNAH12 KIF13A DDX60 NLRP3 GSPT1

2.89e-03839467GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DHX16 DHX33 DNAH12 KIF13A DDX60 NLRP3 GSPT1

2.90e-03840467GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DHX16 DHX33 DNAH12 KIF13A DDX60 NLRP3 GSPT1

2.90e-03840467GO:0016818
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1C CACNB2

5.04e-0346462GO:0005245
GeneOntologyMolecularFunctionretinoid binding

UGT2B4 UGT2B7

5.47e-0348462GO:0005501
GeneOntologyMolecularFunctionADP binding

MYO7A NLRP3

5.47e-0348462GO:0043531
GeneOntologyMolecularFunctionisoprenoid binding

UGT2B4 UGT2B7

5.70e-0349462GO:0019840
GeneOntologyMolecularFunctionhelicase activity

DHX16 DHX33 DDX60

5.75e-03158463GO:0004386
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.51e-098464GO:0070980
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.50e-0910464GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.06e-0812464GO:0052697
GeneOntologyBiologicalProcesscellular glucuronidation

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.26e-0721464GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.12e-0726464GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.12e-0726464GO:0006063
GeneOntologyBiologicalProcessbenzene-containing compound metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.35e-0637464GO:0042537
GeneOntologyBiologicalProcessxenobiotic catabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.35e-0637464GO:0042178
GeneOntologyBiologicalProcessandrogen metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.51e-0638464GO:0008209
GeneOntologyBiologicalProcessestrogen metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.42e-0652464GO:0008210
GeneOntologyBiologicalProcessmembrane depolarization during atrial cardiac muscle cell action potential

CACNA1C CACNB2

1.46e-053462GO:0098912
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNB2

4.85e-055462GO:1904879
GeneOntologyBiologicalProcessmembrane depolarization during AV node cell action potential

CACNA1C CACNB2

7.26e-056462GO:0086045
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT2B4 UGT2B7 FANCB UGT2B28 UGT2B11

1.32e-04222465GO:0071466
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.73e-04141464GO:0006805
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

CACNA1C CACNB2

3.17e-0412462GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

CACNA1C CACNB2

3.17e-0412462GO:0086016
GeneOntologyBiologicalProcessactin filament-based movement

CACNA1C CACNB2 FGF13 MYO7A

3.73e-04153464GO:0030048
GeneOntologyBiologicalProcesshormone metabolic process

UGT2B4 UGT2B7 CHST9 UGT2B28 UGT2B11

4.26e-04286465GO:0042445
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

CACNA1C CACNB2

5.02e-0415462GO:0086067
GeneOntologyBiologicalProcesspositive regulation of cation transmembrane transport

CACNA1C CACNB2 FGF13 F2

6.06e-04174464GO:1904064
GeneOntologyBiologicalProcessregulation of hormone levels

UGT2B4 UGT2B7 CACNA1C CHST9 UGT2B28 UGT2B11 F2

7.43e-04684467GO:0010817
GeneOntologyBiologicalProcessprotein localization to plasma membrane

CACNB2 FGF13 RAPGEF6 KIF13A FYB2

7.50e-04324465GO:0072659
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell communication

CACNA1C CACNB2

8.12e-0419462GO:0086066
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell signaling

CACNA1C CACNB2

8.12e-0419462GO:0086026
GeneOntologyBiologicalProcessatrial cardiac muscle cell action potential

CACNA1C CACNB2

8.12e-0419462GO:0086014
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transmembrane transport

CACNA1C CACNB2 FGF13 F2

8.75e-04192464GO:0034767
GeneOntologyBiologicalProcesschondroitin sulfate biosynthetic process

CHST9 UGDH

9.01e-0420462GO:0030206
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1C CACNB2 FGF13

9.65e-0487463GO:0086001
GeneOntologyBiologicalProcessregulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNB2

1.09e-0322462GO:1902514
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1C CACNB2 FGF13

1.17e-0393463GO:0086003
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA1C CACNB2

1.19e-0323462GO:0086012
GeneOntologyBiologicalProcesscalcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNB2

1.19e-0323462GO:0061577
GeneOntologyCellularComponentnuclear outer membrane

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.77e-0640464GO:0005640
GeneOntologyCellularComponentCA3 pyramidal cell dendrite

SLC4A10 MAP2

1.42e-053462GO:0097442
GeneOntologyCellularComponentNLRP3 inflammasome complex

DHX33 NLRP3

1.32e-048462GO:0072559
GeneOntologyCellularComponentbasal dendrite

SLC4A10 MAP2

2.11e-0410462GO:0097441
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1C CACNB2

3.08e-0412462GO:1990454
GeneOntologyCellularComponentorganelle outer membrane

UGT2B4 UGT2B7 TOMM20L UGT2B28 UGT2B11

3.58e-04279465GO:0031968
GeneOntologyCellularComponentouter membrane

UGT2B4 UGT2B7 TOMM20L UGT2B28 UGT2B11

3.70e-04281465GO:0019867
GeneOntologyCellularComponentT-tubule

CACNA1C CACNB2 AHNAK

7.01e-0479463GO:0030315
GeneOntologyCellularComponentcanonical inflammasome complex

DHX33 NLRP3

7.09e-0418462GO:0061702
GeneOntologyCellularComponentsarcolemma

CACNA1C CACNB2 FGF13 AHNAK

8.01e-04190464GO:0042383
GeneOntologyCellularComponentapical dendrite

SLC4A10 MAP2

2.25e-0332462GO:0097440
DomainUDPGT

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

1.28e-0921455PS00375
DomainUDPGT

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

1.28e-0921455PF00201
DomainUDP_glucos_trans

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

1.28e-0921455IPR002213
DomainP-loop_NTPase

DHX16 CACNB2 DHX33 DNAH12 KIF13A MYO7A DDX60 NLRP3 GSPT1

1.60e-04848459IPR027417
DomainDEAD

DHX16 DHX33 DDX60

7.23e-0473453PF00270
DomainDEAD/DEAH_box_helicase_dom

DHX16 DHX33 DDX60

7.23e-0473453IPR011545
DomainDUF1605

DHX16 DHX33

7.54e-0417452IPR011709
DomainOB_NTP_bind

DHX16 DHX33

7.54e-0417452PF07717
DomainHA2

DHX16 DHX33

8.47e-0418452PF04408
DomainHelicase-assoc_dom

DHX16 DHX33

8.47e-0418452IPR007502
DomainHA2

DHX16 DHX33

8.47e-0418452SM00847
Domain-

DHX16 CACNB2 DHX33 DNAH12 MYO7A DDX60 GSPT1

1.90e-037464573.40.50.300
DomainHelicase_C

DHX16 DHX33 DDX60

2.18e-03107453PF00271
DomainHELICc

DHX16 DHX33 DDX60

2.18e-03107453SM00490
DomainHelicase_C

DHX16 DHX33 DDX60

2.24e-03108453IPR001650
DomainHELICASE_CTER

DHX16 DHX33 DDX60

2.30e-03109453PS51194
DomainHELICASE_ATP_BIND_1

DHX16 DHX33 DDX60

2.30e-03109453PS51192
DomainDEXDc

DHX16 DHX33 DDX60

2.30e-03109453SM00487
DomainHelicase_ATP-bd

DHX16 DHX33 DDX60

2.36e-03110453IPR014001
DomainDNA/RNA_helicase_DEAH_CS

DHX16 DHX33

3.21e-0335452IPR002464
DomainDEAH_ATP_HELICASE

DHX16 DHX33

3.78e-0338452PS00690
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

1.09e-1124326MM14599
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

1.43e-1125326M17787
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

2.24e-0925325MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

2.24e-0925325M605
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

2.76e-0926325M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

4.11e-0928325M19580
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

4.43e-0844325M45014
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

4.98e-0845325MM15694
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.05e-0752325M14171
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

1.28e-07107326MM14595
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

1.43e-07109326M18788
PathwayREACTOME_PREDNISONE_ADME

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.88e-0723324MM16639
PathwayREACTOME_PARACETAMOL_ADME

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.70e-0639324MM15695
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.09e-0641324M7399
PathwayREACTOME_DRUG_ADME

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

4.30e-06109325M45012
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.07e-0651324M17726
PathwayREACTOME_DRUG_ADME

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

6.61e-06119325MM15692
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.88e-0655324M14933
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

8.49e-06219326MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

8.71e-06220326M10320
PathwayKEGG_RETINOL_METABOLISM

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.26e-0564324M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.80e-0570324M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.02e-0572324M9257
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CACNA1C CACNB2 FGF13

5.04e-0532323M27455
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT2B4 UGT2B7 CHST9 UGT2B28 UGT2B11

5.29e-05183325M39588
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CACNA1C CACNB2

1.39e-048322MM15197
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT2B4 UGT2B7

4.47e-0414322M39328
PathwayREACTOME_PHASE_2_PLATEAU_PHASE

CACNA1C CACNB2

4.47e-0414322MM15198
PathwayREACTOME_PHASE_2_PLATEAU_PHASE

CACNA1C CACNB2

5.15e-0415322M27456
PathwayKEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING

CACNA1C CACNB2

1.02e-0321322M47950
PathwayWP_IL1_AND_MEGAKARYOCYTES_IN_OBESITY

F2 NLRP3

1.34e-0324322M39399
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1C CACNB2

1.45e-0325322M47948
PathwayREACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION

CACNA1C CACNB2

1.82e-0328322M10679
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1C CACNB2 PPP2R5D

1.85e-03108323M17034
PathwayREACTOME_CARDIAC_CONDUCTION

CACNA1C CACNB2 FGF13

3.13e-03130323M27454
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.02e-10747426074487
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.04e-10847432093886
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

USP7 CACNA1C DNAH12 F2 KIAA0825 MAP2 MYO7A ZNF592

3.17e-0749747836774506
Pubmed

Dynamic interactions between L-type voltage-sensitive calcium channel Cav1.2 subunits and ahnak in osteoblastic cells.

CACNA1C AHNAK

1.79e-06247219261907
Pubmed

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

UGT2B4 UGT2B7

1.79e-06247210222050
Pubmed

Mechanisms and Regulation of Cardiac CaV1.2 Trafficking.

CACNA1C CACNB2

1.79e-06247234072954
Pubmed

The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome.

DHX33 NLRP3

1.79e-06247223871209
Pubmed

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.

UGT2B4 UGT2B7

1.79e-06247217263731
Pubmed

Quantitative analysis of UGT2B28 mRNA expression by real-time RT-PCR and application to human tissue distribution study.

UGT2B28 UGT2B11

1.79e-06247221679149
Pubmed

Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation.

CACNA1C AHNAK

1.79e-06247216319140
Pubmed

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

UGT2B4 UGT2B7

1.79e-06247215319348
Pubmed

New short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channel.

CACNA1C CACNB2

1.79e-06247215339916
Pubmed

Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ₂.

CACNB2 AHNAK

1.79e-06247222497893
Pubmed

Genetic characterization of a new splice variant of the beta2 subunit of the voltage-dependent calcium channel.

CACNA1C CACNB2

1.79e-06247214674701
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.98e-066647419898482
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

USP7 ZNF592 ASH2L SFMBT2 AHNAK

4.16e-0617747526206133
Pubmed

Myosin VIIA is specifically associated with calmodulin and microtubule-associated protein-2B (MAP-2B).

MAP2 MYO7A

5.36e-06347211171103
Pubmed

Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.

CACNA1C CACNB2

5.36e-06347220817017
Pubmed

Chronic atrial fibrillation increases microRNA-21 in human atrial myocytes decreasing L-type calcium current.

CACNA1C CACNB2

5.36e-06347225107449
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B7

5.36e-0634727835904
Pubmed

Functional properties of the CaV1.2 calcium channel activated by calmodulin in the absence of alpha2delta subunits.

CACNA1C CACNB2

5.36e-06347219106618
Pubmed

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation.

USP7 NLRP3

5.36e-06347230206189
Pubmed

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

UGT2B4 UGT2B11

5.36e-0634728333863
Pubmed

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

UGT2B4 UGT2B7

5.36e-06347229138287
Pubmed

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.

CACNA1C CACNB2

5.36e-06347217224476
Pubmed

Requirement of the Ca2+ channel β2 subunit for sympathetic PKA phosphorylation.

CACNA1C CACNB2

5.36e-06347233602505
Pubmed

Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability.

SLC4A10 MAP2

5.36e-06347218165320
Pubmed

Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.

UGT2B4 UGT2B7

5.36e-06347222092298
Pubmed

Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits.

CACNA1C CACNB2

1.07e-05447218535142
Pubmed

Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol.

UGT2B4 UGT2B7

1.07e-05447216849011
Pubmed

Regional expression of L-type calcium channel subunits during cardiac development.

CACNA1C CACNB2

1.07e-05447215108317
Pubmed

Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.

CACNA1C CACNB2

1.78e-05547219723630
Pubmed

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

UGT2B4 UGT2B7

1.78e-05547215318931
Pubmed

Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.

CACNA1C CACNB2

1.78e-05547216787652
Pubmed

Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.

CACNA1C MAP2

1.78e-05547219564422
Pubmed

Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.

CACNA1C MAP2

2.67e-05647221224388
Pubmed

Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer.

UGT2B7 UGT2B28

3.74e-05747220056642
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT2B4 UGT2B7

4.98e-05847218052087
Pubmed

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

UGT2B4 UGT2B7

4.98e-05847210748067
Pubmed

The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.

DHX33 NLRP3

4.98e-05847225172487
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B4 UGT2B7

4.98e-05847218719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B4 UGT2B7

4.98e-05847220142249
Pubmed

Biological insights from 108 schizophrenia-associated genetic loci.

SLC4A10 CACNA1C CACNB2 MPHOSPH9 MSL2

5.52e-0530347525056061
Pubmed

Functional skewing of TRIM21-SIRT5 interplay dictates IL-1β production in DSS-induced colitis.

USP7 CS

6.40e-05947235770730
Pubmed

Fibroblast growth factor 13 is a microtubule-stabilizing protein regulating neuronal polarization and migration.

FGF13 MAP2

9.75e-051147222726441
Pubmed

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

CACNA1C CACNB2

9.75e-051147218809727
Pubmed

Transient microglial absence assists postmigratory cortical neurons in proper differentiation.

MAP2 IL6ST

9.75e-051147232242005
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B4 UGT2B7

1.17e-041247220308471
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT2B4 UGT2B7

1.17e-041247218161889
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

USP7 METTL1 CS PPP2R5D KIF13A MAP2 AHNAK GSPT1 UGDH

1.24e-04145547922863883
Pubmed

Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.

CACNA1C CACNB2

1.61e-041447229107716
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1C CACNB2

1.86e-041547220188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1C CACNB2

1.86e-041547224453333
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

CACNB2 RAPGEF6 MYO7A

2.11e-048547323055939
Pubmed

Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.

USP7 SPEN

2.70e-041847219640993
Pubmed

The contribution of de novo coding mutations to autism spectrum disorder.

PPP2R5D SPEN

2.70e-041847225363768
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT2B4 UGT2B7

2.70e-041847220056724
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

USP7 KIF13A DDX60 AHNAK

2.84e-0423447436243803
Pubmed

Identification of novel ARF binding proteins by two-hybrid screening.

AHNAK GSPT1

3.69e-042147216582619
Pubmed

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.

CACNA1C MAP2

4.06e-042247236877136
Pubmed

Gene-environment interaction impacts on heart development and embryo survival.

CACNA1C CACNB2

4.06e-042247230787001
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

USP7 SPEN ZNF592 ASH2L AHNAK

4.20e-0446947527634302
Pubmed

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

CACNA1C CACNB2 MPHOSPH9

4.39e-0410947323974872
Pubmed

Brugada Syndrome

CACNA1C CACNB2

4.84e-042447220301690
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

DNAH12 UGT2B11 ZNF839 MAP2 MYO7A

5.41e-0449647531343991
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP7 RAPGEF6 ZNF839 SPEN MYO7A ZNF592 AHNAK

6.65e-04110547735748872
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

USP7 CS PPP2R5D ZNF592 AHNAK UGDH

7.41e-0480947632129710
Pubmed

Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages.

MAP2 MYO7A

7.59e-043047235320729
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

USP7 RAPGEF6 SPEN ASH2L AHNAK

8.55e-0454947538280479
Pubmed

Maternal diabetes alters transcriptional programs in the developing embryo.

MAP2 IL6ST

8.64e-043247219538749
Pubmed

Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.

SIM2 ASH2L

9.19e-043347224705356
Pubmed

Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.

FGF13 MAP2

9.19e-043347230037926
Pubmed

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

NLRP3 MSL2

1.03e-033547223969696
Pubmed

Downregulation of HERC5 E3 ligase attenuates the ubiquitination of CtBP1 to inhibit apoptosis in colorectal cancer cells.

NLRP3 UGDH

1.16e-033747234147029
Pubmed

Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer.

UGT2B4 UGT2B11

1.22e-033847220214802
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1C CACNB2

1.22e-033847230786075
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

SLC4A10 CACNA1C DHX33 MAP2

1.24e-0334747417114649
CytobandEnsembl 112 genes in cytogenetic band chr4q13

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.09e-05157474chr4q13
Cytoband4q13

UGT2B4 UGT2B7

1.07e-04154724q13
Cytoband4q13.2

UGT2B28 UGT2B11

4.68e-04314724q13.2
GeneFamilyUDP glucuronosyltransferases

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

3.91e-0932355363
GeneFamilyDEAH-box helicases

DHX16 DHX33

4.29e-0416352500
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNB2

1.15e-0326352253
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

MAP2 MYO7A

1.43e-0329352396
CoexpressionWENG_POR_TARGETS_LIVER_UP

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

3.59e-0853465MM1203
CoexpressionTERAMOTO_OPN_TARGETS_CLUSTER_7

SLC4A10 RAPGEF6 UGDH

4.05e-0618463M1203
CoexpressionTERAMOTO_OPN_TARGETS_CLUSTER_7

SLC4A10 RAPGEF6 UGDH

4.81e-0619463MM524
CoexpressionGSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN

FGF13 RAPGEF6 F2 SFMBT2 IL6ST

1.58e-05180465M6878
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

2.04e-05190465MM1311
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 DDX60

2.33e-05330466MM1120
CoexpressionGSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_DN

RAPGEF6 TEF DDX60 SFMBT2 IL6ST

2.55e-05199465M9031
CoexpressionGSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP

FGF13 RAPGEF6 TEF DDX60 SFMBT2

2.62e-05200465M4584
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11

2.68e-05201465MM1294
CoexpressionVANLOO_SP3_TARGETS_DN

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.23e-05103464MM919
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.07e-05121464MM935
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP

UGT2B4 UGT2B7 CS UGT2B28 UGT2B11

1.03e-04267465MM984
CoexpressionBOCHKIS_FOXA2_TARGETS

UGT2B4 UGT2B7 CS UGT2B28 UGT2B11 IL6ST

1.59e-04467466MM1233
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

CHST9 SPEN SFMBT2 AHNAK NLRP3

6.92e-07162465810881210e015c788814e4fe8d7a24c929cf2621
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FANCB PPP2R5D GTDC1 ZNF592 DDX60

1.33e-06185465daea170d827226dda6750bf1838ffd82f070c4d4
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNA1C CACNB2 CHST9 FYB2

7.69e-061224641cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGF13 SFMBT2 AHNAK NLRP3

2.52e-05165464651d40eadb1b34de618af94c167f43635729d43f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 AHNAK IL6ST NLRP3

2.97e-051724647fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 AHNAK IL6ST NLRP3

2.97e-051724642a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCelldroplet-Marrow-nan-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2 KIAA0825 AHNAK IL6ST

3.04e-051734646d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

UGT2B4 CACNA1C CACNB2 FYB2

3.86e-05184464e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHST9 FGF13 F2 FYB2

3.95e-051854645dee5645240637e135677732a35fd416b37367d4
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CACNA1C CACNB2 KIF13A MAP2

4.20e-0518846434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAPGEF6 SFMBT2 IL6ST GSPT1

4.20e-05188464939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.29e-05189464aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 FGF13 SIM2 MAP2

4.29e-051894648c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

CACNA1C CACNB2 CHST9 FYB2

4.29e-051894645e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.29e-051894648977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 FGF13 SIM2 MAP2

4.29e-051894645d902a4660a27548764bf04c6de152b565da835c
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

CACNA1C CACNB2 CHST9 FYB2

4.38e-05190464de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.38e-051904643fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.47e-051914645a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.47e-0519146455ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.65e-05193464f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.65e-0519346442df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UGT2B7 CHST9 FGF13 SIM2

4.75e-05194464e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

UGT2B7 CACNA1C CACNB2 FYB2

4.84e-0519546475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZFHX2 DNAH12 KIAA0825 FYB2

5.04e-0519746474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x5'-Liver-Lymphocytic_T_CD4|Liver / Manually curated celltypes from each tissue

RAPGEF6 AHNAK IL6ST GSPT1

5.04e-051974644891111894b741555f549deec6af8006376d9358
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

USP7 CS AHNAK GSPT1

5.34e-05200464cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

USP7 CS AHNAK GSPT1

5.34e-052004640d76b006d8e8b32174e65e400acd0674354b962c
DrugAC1NOWCJ

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

8.35e-0935465CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

8.35e-0935465CID010436171
Drugtestosterone glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.91e-0841465CID000108192
DrugC1 11-32

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.37e-0818464CID000443077
DrugC11131

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.37e-0818464CID000443076
DrugT4-G

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.53e-0819464CID000152424
DrugAC1NQGK1

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

6.51e-0852465CID005195977
Drugestriol-16-glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

8.51e-0821464CID000122281
Drug4-hydroxybiphenyl

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.24e-0759465CID000007103
Drugestradiol-3-glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.26e-0723464CID000066651
Drugfibrates

UGT2B4 UGT2B7 FANCB UGT2B28 UGT2B11 F2

1.35e-07118466CID000002797
DrugUDP-alpha-d-xylopyranose

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.35e-0760465CID000001165
Drug3-OHBaP

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.73e-0763465CID000025890
DrugL-idaro-1,4-lactone

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.88e-0728464CID000078997
Drug7-hydroxycoumarin glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.34e-0729464CID000125641
Drugeugenol

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

3.65e-0773465CID000003314
Drug7-hydroxycoumarin

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

4.18e-0775465CID005281426
DrugAC1N8H7N

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

5.09e-0778465CID004318740
DrugAC1Q6OQG

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.72e-0733464CID000009686
DrugBP-3,6-quinol

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.72e-0733464CID000119292
Drugestrone-3-glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

7.29e-0735464CID000115255
Drugmenthol

UGT2B4 UGT2B7 UGT2B28 UGT2B11 SPEN

8.79e-0787465CID000001254
Drugl-borneol

UGT2B4 UGT2B7 UGT2B28 UGT2B11

9.17e-0737464CID000010049
Drugglucosiduronate

UGT2B4 UGT2B7 CHST9 UGT2B28 UGT2B11 UGDH

1.20e-06171466CID000000610
Drugharmol

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.26e-0640464CID000068094
DrugBiliton

UGT2B4 UGT2B7 F2 MYO7A

1.40e-0641464CID000002974
Drug2-AF

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.40e-0641464CID000005800
Drug1-naphthol

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.59e-0698465CID000007005
Drugandrosterone glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.70e-0643464CID000114833
Drug7,8-benzoquinoline

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.70e-0643464CID000009191
DrugMS-222

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.87e-0644464CID000011400
Druguridine 5'-diphosphoglucuronic acid

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

2.15e-06189466CID000000390
Drugsalicylamide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.66e-0648464CID000005147
Drugoxazepam

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.97e-0653464CID000004616
Drug2-hydroxyestriol

UGT2B7 UGT2B11

3.99e-062462ctd:C008012
Drug7-methoxycoumarin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.33e-0657464CID000010748
Drugphenolphthalein

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.71e-0658464CID000004764
Drugurochloralic acid

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.12e-0659464CID003036914
Drug4-hydroxyestrone

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.12e-0659464CID000018418
Drugacetaminophen glucuronide

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.12e-0659464CID000083944
DrugSN-38G

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.12e-0659464CID000443154
Drug4-methylumbelliferone

UGT2B4 UGT2B7 CHST9 UGT2B28 UGT2B11

6.88e-06132465CID003364573
DrugUDP - Na

UGT2B4 UGT2B7 UGT3A2 UGT2B28 UGT2B11 UGDH

7.52e-06235466CID000001158
Druganiline

UGT2B4 UGT2B7 METTL1 UGT2B28 UGT2B11

9.81e-06142465CID000006115
DrugMeldola

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.08e-0568464CID000081507
Drugmethoxyresorufin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.15e-0569464CID000119220
Drug5 alpha-dihydroaldosterone

UGT2B4 UGT2B7

1.20e-053462CID003036614
Drug2,2,2-trichloroethanol

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.43e-0573464CID000008259
DrugHymecromone

UGT2B4 UGT2B7 UGT2B11

1.72e-0525463ctd:D006923
Drug16-epiestriol

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.77e-0577464CID000003269
DrugAC1LCF1F

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

1.80e-05161465CID000627275
DrugAC1L1BH2

UGT2B4 UGT2B7 FANCB F2

1.86e-0578464CID000001436
Drugbenzyloxyresorufin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

1.86e-0578464CID000114982
Drugacridine

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.16e-0581464CID000009215
Drugpheophytin

UGT2B4 UGT2B7 FANCB UGT2B28 UGT2B11 UGDH

2.20e-05284466CID000000250
DrugNSC-686960

CACNA1C CACNB2

2.39e-054462CID000192816
Drugaminopyrine

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

2.41e-05171465CID000006009
Drug5 alpha-androstane

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.50e-0584464CID000094144
Drug7-ethoxycoumarin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.74e-0586464CID000035703
Drug4-nitrophenol

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

2.84e-05177465CID000000980
Drugpentoxyresorufin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

2.87e-0587464CID000107683
Drug4-aminobiphenyl

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.58e-0592464CID000007102
Drugp-nitroanisole

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.58e-0592464CID000007485
Drugclofibrate

UGT2B4 UGT2B7 FANCB CS UGT2B28 UGT2B11

3.66e-05311466CID000002796
Drug2-naphthol

UGT2B4 UGT2B7 UGT2B28 UGT2B11

3.73e-0593464CID000008663
DrugNilvadipine

CACNA1C CACNB2

3.98e-055462DB06712
DrugNisoldipine

CACNA1C CACNB2

3.98e-055462DB00401
Drughyodeoxycholic acid

UGT2B4 UGT2B7

3.98e-055462ctd:C010471
DrugAmobarbital

UGT2B4 UGT2B7

3.98e-055462ctd:D000654
DrugB 874-67

CACNA1C CACNB2

3.98e-055462CID000195466
Drugmethyl beta-aminocrotonate

CACNA1C CACNB2

3.98e-055462CID000084253
Drugphenolphthalin

UGT2B4 UGT2B7

3.98e-055462CID000066494
Drugperfluorophenanthrene

CS MAP2

3.98e-055462CID000078972
Drugnemadipine-A

CACNA1C CACNB2

3.98e-055462CID002856102
DrugDCNB

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.06e-0595464CID000007443
Drugethoxyresorufin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.06e-0595464CID000003294
DrugDB04103

UGT2B4 UGT2B7 UGT2B28 UGT2B11

4.40e-0597464CID004469987
Drug2-butyl-6-methoxyphenol

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

4.74e-05197465CID011954184
DrugEpivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

USP7 ZNF839 ZNF592 IL6ST GSPT1

4.85e-051984656838_DN
Drug3-hydroxyandrostan-17-one

UGT2B4 UGT2B7 UGT2B28 UGT2B11

5.36e-05102464CID000000225
DrugUDP-N-acetylglucosamine

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH

5.46e-05203465CID000001167
Drug2-hydroxyestriol

UGT2B4 UGT2B7

5.96e-056462CID000014688
DrugCPU-23

CACNA1C CACNB2

5.96e-056462CID003036051
DrugMagnesium Sulfate

CACNA1C CACNB2

5.96e-056462DB00653
Drugchrysin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.23e-05106464CID005281607
Drugfluconazole

UGT2B4 UGT2B7 UGT2B28 UGT2B11

6.46e-05107464CID000003365
Drugdioxin

UGT2B4 UGT2B7 UGT2B28 SIM2 TEF UGT2B11

6.72e-05347466CID000015625
Drug2-naphthylamine

UGT2B4 UGT2B7 UGT2B28 UGT2B11

7.20e-05110464CID000007057
Drugarabinosyluracil

UGT2B4 UGT2B7 UGT2B28 UGT2B11 UGDH MSL2

7.51e-05354466CID000001177
Drugbenzo(a)pyrene

USP7 UGT2B4 UGT2B7 CS UGT2B28 UGT2B11

7.98e-05358466CID000002336
DrugAmlodipine

CACNA1C CACNB2

8.33e-057462DB00381
DrugIsradipine

CACNA1C CACNB2

8.33e-057462DB00270
Drugoxazepam glucuronide

UGT2B4 UGT2B7

8.33e-057462CID000160870
Drugranirestat

UGT2B4 UGT2B7

8.33e-057462ctd:C115070
Druglithocholic acid

UGT2B4 UGT2B7 UGT2B28 UGT2B11

8.85e-05116464CID000009903
Drugethoxyquin

UGT2B4 UGT2B7 UGT2B28 UGT2B11

8.85e-05116464CID000003293
DrugAC1Q7AUJ

UGT2B4 UGT2B7 UGT2B28 UGT2B11

9.15e-05117464CID000003303
Drugalpha-naphthoflavone

UGT2B4 UGT2B7 UGT2B28 UGT2B11

9.46e-05118464CID000011790
Drugbenzphetamine

UGT2B4 UGT2B7 UGT2B28 UGT2B11

9.77e-05119464CID000002341
Drugbasic copper carbonate

SPEN NLRP3

1.11e-048462CID000025503
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B7 UGT2B11

2.58e-079443EFO_0600040
DiseaseX-19141 measurement

UGT2B4 UGT2B7 UGT2B11

8.76e-0713443EFO_0800799
Diseasephosphatidylcholine 36:4 measurement

UGT2B4 UGT2B28 UGT2B11

2.49e-0618443EFO_0010382
DiseaseX-24947 measurement

UGT2B4 UGT2B7 UGT2B11

4.67e-0622443EFO_0800910
Diseasevitamin D deficiency

UGT2B4 UGT2B7 UGT2B11

2.32e-0537443EFO_0003762
Diseasebipolar disorder, anorexia nervosa

CACNA1C ZNF592

3.25e-056442MONDO_0004985, MONDO_0005351
Diseaseschizophrenia, anorexia nervosa

CACNA1C MPHOSPH9 ZNF592

5.11e-0548443MONDO_0005090, MONDO_0005351
DiseaseBrugada syndrome

CACNA1C CACNB2

6.05e-058442cv:C1142166
Diseasedisease progression measurement

UGT2B4 UGT2B7 UGT2B11

1.05e-0461443EFO_0008336
DiseaseShortened QT interval

CACNA1C CACNB2

1.19e-0411442C0151879
Diseaseattention deficit hyperactivity disorder, schizophrenia

CACNA1C MPHOSPH9 MSL2

1.21e-0464443EFO_0003888, MONDO_0005090
Diseaseautism spectrum disorder, schizophrenia

CACNA1C CACNB2 MPHOSPH9 F2 ZNF592

1.24e-04327445EFO_0003756, MONDO_0005090
Diseasechildhood trauma measurement, alcohol consumption measurement

CS SIM2 SFMBT2

1.65e-0471443EFO_0007878, EFO_0007979
Diseasediverticular disease

UGT2B4 UGT2B7 CACNB2 UGT2B11

4.21e-04236444EFO_0009959
Diseasehypertrophic cardiomyopathy (is_implicated_in)

CACNB2 CS

4.93e-0422442DOID:11984 (is_implicated_in)
DiseaseBrugada Syndrome (disorder)

CACNA1C CACNB2

5.87e-0424442C1142166
Diseasesensorineural hearing loss (is_implicated_in)

F2 MYO7A

1.11e-0333442DOID:10003 (is_implicated_in)
Diseasebipolar I disorder

CACNA1C CACNB2 ZNF592

1.23e-03141443EFO_0009963

Protein segments in the cluster

PeptideGeneStartEntry
LKFWPKTHSPKEVMF

PPP2R5D

366

Q14738
KFKMPDVHFKSPQIS

AHNAK

4506

Q09666
YKAKELEDPHAKKMP

DHX16

1016

O60231
PAVPMKDHDAIKLFV

CELF6

36

Q96J87
PHSKEKRMPFFKKTE

CACNB2

256

Q08289
HPKTMFSKDKDIIPF

ASH2L

186

Q9UBL3
SHMFPEEEQPKKIGK

KIAA0825

471

Q8IV33
TKRPPKADKEAHVMA

DDX60

1156

Q8IY21
SKEPHNAKFPAPMDK

DNAH12

2426

Q6ZR08
KDPKEFMEHIDVPKG

MPHOSPH9

61

Q99550
DKAVKEKIPSHHFMP

MSL2

431

Q9HCI7
KKVGFNPKKDIHFMP

GSPT1

246

P15170
FPKKKPIEHMEDLFA

FANCB

636

Q8NB91
FQATHPVMDLKAFPK

IL6ST

421

P40189
HLKEKAVPMPEASAF

CACNA1C

866

Q13936
REFALKHLPNDPMFK

CS

361

O75390
KMAAFPLEPKFAKTI

DHX33

496

Q9H6R0
AAHFLPKPLKVAMYK

FGF13

191

Q92913
LDKPAATVFKKEFPM

FAM172BP

296

A6NC97
KDPESFFKVLMHLKD

GTDC1

296

Q4AE62
PKITTEKKNHPDFMI

LINC00597

66

Q9H2U6
LDPNFPATLFKDKMK

MINAR1

56

Q9UPX6
FFKPLMPVKEEHKKR

KIF13A

1466

Q9H1H9
DLKKFKMHLEDYPPQ

NLRP3

21

Q96P20
PLFPVVKKDMTFLHE

RAPGEF6

1011

Q8TEU7
FPYPEPSAKHEDKKM

FYB2

371

Q5VWT5
SHVFSSKKPMLPAKF

SIM2

451

Q14190
HKFAEEDLKPQPMIK

TEF

206

Q10587
NPKFHMPEDVREKKE

CHST9

81

Q7L1S5
ERIHKKMLKPAFIFD

UGDH

426

O60701
LHKMKKAAIDPSAPA

ZFHX2

1216

Q9C0A1
DSPPSKKKRMDHVDF

SPEN

1221

Q96T58
HCKPAKPLPKEMEEF

UGT2B4

281

P06133
MFDHFCKKEPKPEPL

ZNF592

196

Q92610
MSKAHPPELKKFTDK

SNRPGP15

1

A8MWD9
EVDLHFMKKIPPGAE

SLC4A10

316

Q6U841
KFPLPMEVFKDHADL

SFMBT2

281

Q5VUG0
HCKPAKPLPKEMEEF

UGT2B11

281

O75310
FKIEEPHEAKPDKMA

MAP2

366

P11137
MKVEKDHLAKPFFPA

ZNF839

386

A8K0R7
LKVFKHTLPPKVFEM

TOMM20L

111

Q6UXN7
MKLKKPVAFSDYIHP

F2

466

P00734
HCKPAKPLPKEMEEF

UGT2B28

281

Q9BY64
LNHKRGPFMPDFKKE

UGT3A2

56

Q3SY77
HCKPAKPLPKEMEDF

UGT2B7

281

P16662
LPKFDKDHDVMLFLK

USP7

676

Q93009
KMFFLFPDPHFKRTK

METTL1

156

Q9UBP6
IKPNEFKKPMLFDRH

MYO7A

636

Q13402