Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

DAB2 APP PICALM

1.52e-0434613GO:0050750
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

DAB2 APP PICALM

2.29e-0439613GO:0070325
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6A TNRC6B TNRC6C

7.91e-0614593GO:0060213
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6A TNRC6B TNRC6C

1.21e-0516593GO:0060211
GeneOntologyBiologicalProcesspositive regulation of receptor-mediated endocytosis

SELE DAB2 APP TF

4.05e-0567594GO:0048260
GeneOntologyBiologicalProcesscollateral sprouting in absence of injury

COBL APP

8.00e-055592GO:0048669
GeneOntologyBiologicalProcessregulation of receptor-mediated endocytosis

SELE DAB2 APP TF PICALM

8.36e-05156595GO:0048259
GeneOntologyBiologicalProcessnuclear-transcribed mRNA poly(A) tail shortening

TNRC6A TNRC6B TNRC6C

1.14e-0433593GO:0000289
GeneOntologyBiologicalProcesspositive regulation of receptor internalization

SELE DAB2 APP

1.25e-0434593GO:0002092
GeneOntologyCellularComponentclathrin-coated pit

SELE DAB2 APP TF PICALM

3.08e-0680595GO:0005905
GeneOntologyCellularComponentendosome to plasma membrane transport vesicle

APP PICALM

2.35e-053592GO:0070381
GeneOntologyCellularComponentP-body

TNRC6A TNRC6B TNRC6C YTHDF2

1.98e-04102594GO:0000932
GeneOntologyCellularComponentendoplasmic reticulum lumen

EDEM3 SCG3 APP POGLUT2 F5 TF

3.40e-04332596GO:0005788
DomainAgo_hook

TNRC6A TNRC6B TNRC6C

3.31e-083613PF10427
DomainTNRC6_PABC-bd

TNRC6A TNRC6B TNRC6C

3.31e-083613IPR032226
DomainArgonaute_hook_dom

TNRC6A TNRC6B TNRC6C

3.31e-083613IPR019486
DomainTNRC6-PABC_bdg

TNRC6A TNRC6B TNRC6C

3.31e-083613PF16608
DomainM_domain

TNRC6A TNRC6C

1.05e-052612PF12938
DomainGW182_M_dom

TNRC6A TNRC6C

1.05e-052612IPR026805
DomainBAT2_N

PRRC2A PRRC2B

3.14e-053612PF07001
DomainBAT2_N

PRRC2A PRRC2B

3.14e-053612IPR009738
DomainPRRC2

PRRC2A PRRC2B

3.14e-053612IPR033184
DomainUBA-like

TNRC6A TNRC6B TNRC6C

1.20e-0364613IPR009060
DomainCupredoxin

F5 PKHD1L1

2.32e-0322612IPR008972
DomainJmjC

KDM6A JMJD1C

2.77e-0324612PF02373
Domain-

PCF11 PICALM

3.24e-03266121.25.40.90
DomainENTH_VHS

PCF11 PICALM

4.02e-0329612IPR008942
DomainTIG

CAMTA1 PKHD1L1

4.59e-0331612PF01833
DomainIg_E-set

CAMTA1 POGLUT2 PKHD1L1

4.78e-03104613IPR014756
DomainJMJC

KDM6A JMJD1C

4.89e-0332612PS51184
DomainIPT

CAMTA1 PKHD1L1

4.89e-0332612IPR002909
DomainJmjC_dom

KDM6A JMJD1C

4.89e-0332612IPR003347
DomainJmjC

KDM6A JMJD1C

5.19e-0333612SM00558
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6A TNRC6B TNRC6C

7.93e-077413M46421
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

TNRC6A TNRC6B TNRC6C

1.90e-069413M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

TNRC6A TNRC6B TNRC6C

1.90e-069413M46436
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

TNRC6A TNRC6B TNRC6C

2.70e-0610413M48013
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

TNRC6A TNRC6B TNRC6C

6.40e-0613413M46434
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

TNRC6A TNRC6B TNRC6C

1.51e-0517413M27788
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

TNRC6A TNRC6B TNRC6C

2.14e-0519413M48238
PathwayREACTOME_PTEN_REGULATION

PSMF1 TNRC6A TNRC6B TNRC6C HDAC7

4.89e-05139415M27646
PathwayREACTOME_TGFBR3_EXPRESSION

TNRC6A TNRC6B TNRC6C

7.11e-0528413M48253
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

TNRC6A TNRC6B TNRC6C

1.07e-0432413M48012
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

TNRC6A TNRC6B TNRC6C

1.07e-0432413M27900
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6A TNRC6B

1.23e-046412MM15083
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

TNRC6A TNRC6B TNRC6C

1.28e-0434413M46422
PathwayREACTOME_ONCOGENE_INDUCED_SENESCENCE

TNRC6A TNRC6B TNRC6C

1.40e-0435413M27190
PathwayREACTOME_MAPK6_MAPK4_SIGNALING

PSMF1 TNRC6A TNRC6B TNRC6C

1.49e-0493414M27572
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

TNRC6A TNRC6B TNRC6C

1.66e-0437413M29790
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

TNRC6A TNRC6B TNRC6C

2.25e-0441413M29748
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

PSMF1 PDE1B TNRC6A TNRC6B TNRC6C HDAC7

2.67e-04313416M27867
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

TNRC6A TNRC6B TNRC6C

3.39e-0447413M29777
PathwayREACTOME_SIGNALING_BY_TGFBR3

TNRC6A TNRC6B TNRC6C

3.83e-0449413M48250
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

SCG3 APP F5 TF

3.96e-04120414MM14982
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

SCG3 APP F5 TF

4.49e-04124414M27285
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

SCG3 APP F5 TF

5.37e-04130414MM15455
PathwayREACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2

SCG3 APP F5 TF

5.69e-04132414M724
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

TNRC6A TNRC6B TNRC6C

6.31e-0458413M11980
PathwayREACTOME_SIGNALING_BY_NOTCH

PSMF1 TNRC6A TNRC6B TNRC6C HDAC7

6.97e-04246415M10189
PathwayREACTOME_CA2_PATHWAY

TNRC6A TNRC6B TNRC6C

7.67e-0462413M27321
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

TNRC6A TNRC6B TNRC6C

8.03e-0463413M27862
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

PSMF1 TNRC6A TNRC6B TNRC6C

8.30e-04146414M27288
PathwayREACTOME_HEMOSTASIS

SELE PDE1B SCG3 APP F5 TF JMJD1C

1.17e-03571417MM14472
PathwayREACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS

PCF11 WDR33

1.52e-0320412M497
PathwayREACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS

PCF11 WDR33

1.52e-0320412MM15469
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

TNRC6A TNRC6B TNRC6C

1.85e-0384413M27495
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

TNRC6A TNRC6B TNRC6C

2.25e-0390413M820
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

PCF11 PSMF1 SF3B1 WDR33 TNRC6A TNRC6B ZNF235 KDM6A HDAC7

2.26e-031022419MM15436
PathwayKEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION

KDM6A JMJD1C

2.57e-0326412M47439
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TNRC6A TNRC6B TNRC6C

2.63e-0395413M48268
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

TNRC6A TNRC6B TNRC6C

2.70e-0396413M27792
PathwayREACTOME_HEMOSTASIS

SELE PDE1B SCG3 APP F5 TF JMJD1C

3.13e-03679417M8395
PathwayWP_KLEEFSTRA_SYNDROME

ASXL1 KDM6A

3.19e-0329412M48076
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA

PCF11 WDR33

3.19e-0329412M783
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA

PCF11 WDR33

3.19e-0329412MM15444
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

DAB2 TF PICALM

3.21e-03102413MM15498
Pubmed

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.

TNRC6A TNRC6B TNRC6C

5.39e-09362334108231
Pubmed

Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.

TNRC6A TNRC6B TNRC6C

5.39e-09362316880270
Pubmed

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.

TNRC6A TNRC6B TNRC6C

5.39e-09362331670606
Pubmed

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.

TNRC6A TNRC6B TNRC6C

2.16e-08462321063388
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

C2CD3 SVIL TNRC6A TNRC6B CEP152 TRIM24 JMJD1C

3.98e-0818462732908313
Pubmed

Human transcription factor protein interaction networks.

PCF11 ASXL1 WDR33 SVIL TNRC6A TNRC6B CEP152 TNRC6C TRIM24 KDM6A PRRC2A JMJD1C YTHDF2 PRRC2B

1.68e-071429621435140242
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

TNRC6A TNRC6B TNRC6C

1.88e-07762319470757
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

TNRC6A TNRC6B TNRC6C

1.88e-07762319383768
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PLEKHG1 C2CD3 CALD1 SVIL TNRC6A TNRC6B COBL CEP152 TNRC6C YTHDF2 PRRC2B

2.95e-07853621128718761
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

WDR33 TNRC6A TNRC6B TNRC6C JMJD1C PRRC2B

3.17e-0715262638360978
Pubmed

TRIM24 is an insulin-responsive regulator of P-bodies.

SF3B1 TNRC6A TNRC6B TNRC6C TRIM24

3.31e-078062535803934
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

EXPH5 SVIL TNRC6A TNRC6B PICALM JMJD1C PRRC2B

4.50e-0726362734702444
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PLEKHG1 ASXL1 SPHKAP TNRC6B COBL TNRC6C CAMTA1 PRRC2B

6.39e-0740762812693553
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

PCF11 SLC4A7 WDR33 TNRC6A DAB2 JMJD1C

8.54e-0718062635198878
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

PCF11 WDR33 TNRC6A TNRC6B TRIM24 JMJD1C YTHDF2 PRRC2B

1.52e-0645762832344865
Pubmed

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

SF3B1 TNRC6A TNRC6B TNRC6C POGLUT2 JMJD1C YTHDF2

1.57e-0631762730997501
Pubmed

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

TNRC6A TNRC6B TNRC6C

1.94e-061462319716330
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

TNRC6A DAB2 TNRC6B COBL CEP152 PICALM

2.04e-0620962636779422
Pubmed

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.

TNRC6A TNRC6B TNRC6C

2.42e-061562321981923
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

PCF11 SF3B1 CALD1 WDR33 COBL PRRC2A YTHDF2

2.49e-0634062724332808
Pubmed

Role of GW182 protein in the cell.

TNRC6A TNRC6B

3.13e-06262229791863
Pubmed

Lack of association between PICALM rs3851179 polymorphism and Alzheimer's disease in Chinese population and APOEε4-negative subgroup.

APP PICALM

3.13e-06262223040034
Pubmed

Prognostic interaction between bone marrow morphology and SF3B1 and ASXL1 mutations in myelodysplastic syndromes with ring sideroblasts.

ASXL1 SF3B1

3.13e-06262229434284
Pubmed

Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis.

APP PICALM

3.13e-06262222539346
Pubmed

The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.

TF PICALM

3.13e-06262222363754
Pubmed

A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity.

APP PICALM

3.13e-06262222888099
Pubmed

The role of PTB domain containing adaptor proteins on PICALM-mediated APP endocytosis and localization.

APP PICALM

3.13e-06262231300465
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

PCF11 SF3B1 CCDC88B F5 PRRC2A JMJD1C PRRC2B

3.69e-0636162726167880
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

SLC4A7 SF3B1 CALD1 APP PRRC2A JMJD1C C18orf32

4.73e-0637562732788342
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

SVIL TNRC6A TNRC6B CEP152 CAMTA1 PRRC2A JMJD1C C18orf32

4.92e-0653662815840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

SVIL TNRC6A TNRC6B CEP152 CAMTA1 PRRC2A JMJD1C C18orf32

5.06e-0653862810512203
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PCF11 SF3B1 CALD1 WDR33 MCM4 TRIM24 PRRC2A PICALM JMJD1C YTHDF2

6.80e-06954621036373674
Pubmed

Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.

TNRC6A TNRC6B TNRC6C

8.11e-062262322187428
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PCF11 WDR33 TRIM24 KDM6A JMJD1C PRRC2B

8.48e-0626862633640491
Pubmed

Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.

TNRC6A TNRC6B TNRC6C

9.31e-062362328811219
Pubmed

Genetic landscape of recurrent ASXL1, U2AF1, SF3B1, SRSF2, and EZH2 mutations in 304 Chinese patients with myelodysplastic syndromes.

ASXL1 SF3B1

9.37e-06362226508027
Pubmed

Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies.

CFHR1 ADGRE2

9.37e-06362231273197
Pubmed

The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide.

APP PICALM

9.37e-06362219450545
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SF3B1 CALD1 TNRC6B TRIM24 PICALM JMJD1C YTHDF2

1.42e-0544462734795231
Pubmed

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.

TNRC6A TNRC6C

1.87e-05462223172285
Pubmed

Mutations and karyotype predict treatment response in myelodysplastic syndromes.

ASXL1 SF3B1

1.87e-05462230152885
Pubmed

Crystal structures of the Dab homology domains of mouse disabled 1 and 2.

DAB2 APP

1.87e-05462212826668
Pubmed

Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.

TNRC6A TNRC6C

1.87e-05462220181956
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PLEKHG1 C2CD3 SLC4A7 EXPH5 SVIL COBL CEP152 HDAC7 YTHDF2

2.10e-0586162936931259
Pubmed

APP, APOE, complement receptor 1, clusterin and PICALM and their involvement in the herpes simplex life cycle.

APP PICALM

3.12e-05562220674675
Pubmed

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.

TNRC6B TNRC6C

3.12e-05562219838187
Pubmed

Selectin haplotypes and the risk of venous thrombosis: influence of linkage disequilibrium with the factor V Leiden mutation.

SELE F5

3.12e-05562218182036
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PCF11 C2CD3 SF3B1 CALD1 WDR33 SCG3 PCDHGA1 CAPRIN2 STOX1 PRRC2B MYBPC1

4.35e-051442621135575683
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

PLEKHG1 C2CD3 CEP152

4.35e-053862336674791
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TNRC6A TNRC6B TNRC6C PRRC2B LDB2

4.47e-0521862533378226
Pubmed

Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta.

APP TF

4.67e-05662218813964
Pubmed

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries.

DAB2 TF

4.67e-05662212857860
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SF3B1 PDE1B SPHKAP SVIL TNRC6B PRRC2A PICALM PRRC2B LDB2

5.02e-0596362928671696
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

SLC4A7 SVIL ZNF235 APP JMJD1C PRRC2B

5.26e-0537162615747579
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CALD1 WDR33 TNRC6B KDM6A PRRC2A JMJD1C PRRC2B

5.46e-0554962738280479
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF469 STOX1 ZNF235

5.89e-054262334673265
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

WDR33 MCM4 PRRC2A

6.33e-054362334672947
Pubmed

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.

APP TF

6.53e-05762218353773
Pubmed

Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.

SELE F5

6.53e-0576221694218
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PCF11 SF3B1 SVIL DAB2 MCM4 KDM6A HDAC7 PRRC2A

6.80e-0577462815302935
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

TNRC6A TNRC6B PRRC2A JMJD1C PRRC2B

7.33e-0524262534011540
Pubmed

A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.

TNRC6A TNRC6C

8.69e-05862224768540
Pubmed

The mutational landscape of lethal castration-resistant prostate cancer.

ASXL1 KDM6A

8.69e-05862222722839
Pubmed

Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.

DAB2 APP

1.12e-04962211247302
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

SVIL TNRC6A COBL PRRC2A YTHDF2

1.31e-0427462534244482
Pubmed

Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.

DAB2 PICALM

1.39e-041062227237791
Pubmed

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

APP PICALM

1.39e-041062226005850
Pubmed

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.

TNRC6A TNRC6C

1.39e-041062221984185
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PLEKHG1 CALD1 TNRC6A TNRC6B CEP152 HDAC7

1.44e-0444662624255178
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

EDEM3 ZNF469 CAPRIN2 TNRC6A TNRC6B APP TRIM24 TF PRRC2B

1.54e-04111662931753913
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

PCF11 TNRC6A TRIM24

1.63e-045962328813667
Pubmed

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.

TNRC6A TNRC6C

1.70e-041162221984184
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

C2CD3 TNRC6A TNRC6B PRRC2A YTHDF2 PRRC2B

1.74e-0446262631138677
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PCF11 EDEM3 ASXL1 SF3B1 CALD1 SVIL CEP152 TF PRRC2B

1.99e-04115562920360068
Pubmed

TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression.

MCM4 TRIM24

2.04e-041262230479348
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

TNRC6A TNRC6B MCM4 TF

2.25e-0416662435687106
Pubmed

A human MAP kinase interactome.

SF3B1 EXPH5 TNRC6A DAB2 COBL CCDC88B

2.29e-0448662620936779
Pubmed

Genetic influences on blood pressure within the Stanislas Cohort.

SELE F5

2.41e-041362215076187
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SF3B1 CALD1 TNRC6B MCM4 PRRC2A PICALM YTHDF2 PRRC2B

2.46e-0493462833916271
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

APP KDM6A YTHDF2

2.60e-046962332238831
Pubmed

Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.

TRIM24 JMJD1C

2.81e-041462211500849
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

ASXL1 SVIL MCM4 PRRC2A PRRC2B

3.19e-0433262537433992
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

EDEM3 SLC4A7 WDR33 TNRC6A TNRC6B JMJD1C YTHDF2

3.23e-0473362734672954
Pubmed

Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population.

SELE F5

3.23e-041562211341749
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

EDEM3 SLC4A7 TNRC6B APP POGLUT2 PICALM YTHDF2 PRRC2B

4.07e-04100762834597346
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

TRIM24 KDM6A JMJD1C

4.48e-048362328794006
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PCF11 SLC4A7 SF3B1 TNRC6A TNRC6B PKHD1L1 PRRC2B

4.58e-0477762735844135
Pubmed

Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21.

APP TF

4.70e-04186221783381
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

EXPH5 CAPRIN2 AKNAD1 COBL

5.29e-0420862433230847
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PCF11 C2CD3 SVIL TNRC6A APP KDM6A PRRC2A PRRC2B

5.33e-04104962827880917
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZSCAN20 CALD1 ZNF235 TRIM24 PKHD1L1 KDM6A LDB2

5.77e-0480862720412781
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

ASXL1 KDM6A

5.82e-042062229785026
Pubmed

Characterization of the proteins of isolated human platelet alpha-granules. Evidence for a separate alpha-granule-pool of the glycoproteins IIb and IIIa.

SCG3 TF

6.42e-04216226457647
Pubmed

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.

TNRC6B PRRC2B

6.42e-042162233029523
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

PCF11 SF3B1 WDR33 SVIL TNRC6A TNRC6B PRRC2A YTHDF2 PRRC2B

6.92e-04137162936244648
Pubmed

Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.

SELE F5

7.06e-042262212871600
Pubmed

PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA.

PRRC2A PRRC2B

7.06e-042262238507412
Pubmed

The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.

TNRC6A TNRC6B PRRC2A

7.06e-049762337151849
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ASXL1 TNRC6B TNRC6C CAMTA1

7.09e-0422562412168954
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

SF3B1 CALD1 DAB2 PRRC2A

7.21e-0422662437839992
InteractionCNOT9 interactions

PCF11 PLEKHG1 ANXA2R TNRC6A TNRC6B CEP152 TNRC6C PRRC2A JMJD1C YTHDF2 PRRC2B

1.08e-102316211int:CNOT9
InteractionCNOT7 interactions

ANXA2R TNRC6A TNRC6B TNRC6C APP PRRC2A YTHDF2 PRRC2B

1.09e-08140628int:CNOT7
InteractionTNRC6A interactions

PCF11 TNRC6A TNRC6B CEP152 TNRC6C TRIM24 PRRC2A PICALM YTHDF2 PRRC2B

1.30e-082806210int:TNRC6A
InteractionCNOT6L interactions

ANXA2R TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

1.42e-0893627int:CNOT6L
InteractionGARRE1 interactions

PLEKHG1 TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

4.34e-08167628int:GARRE1
InteractionSMG7 interactions

PCF11 TNRC6A TNRC6B CEP152 TNRC6C TRIM24 PRRC2A JMJD1C YTHDF2 PRRC2B

4.45e-083196210int:SMG7
InteractionPAN3 interactions

SVIL TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2

4.74e-0865626int:PAN3
InteractionCNOT2 interactions

CALD1 TNRC6A TNRC6B TNRC6C PRRC2A JMJD1C YTHDF2 PRRC2B

7.12e-08178628int:CNOT2
InteractionZFP36 interactions

TNRC6A TNRC6B TNRC6C APP HDAC7 PRRC2A YTHDF2 PRRC2B

8.11e-08181628int:ZFP36
InteractionALG13 interactions

PCF11 WDR33 TNRC6A TNRC6B PRRC2A JMJD1C YTHDF2 PRRC2B

8.82e-08183628int:ALG13
InteractionSYNE3 interactions

PLEKHG1 C2CD3 EXPH5 TNRC6A TNRC6B CEP152 TNRC6C APP POGLUT2 PICALM PRRC2B

9.70e-084446211int:SYNE3
InteractionSMG5 interactions

TNRC6A TNRC6B CEP152 APP PRRC2A YTHDF2

2.23e-0784626int:SMG5
InteractionCNOT3 interactions

ANXA2R TNRC6A TNRC6B CEP152 TNRC6C TRIM24 PRRC2A YTHDF2

2.27e-07207628int:CNOT3
InteractionCELF1 interactions

PCF11 WDR33 TNRC6A TNRC6B TNRC6C APP PRRC2A YTHDF2 PRRC2B

2.29e-07288629int:CELF1
InteractionCPEB1 interactions

TNRC6A TNRC6B TNRC6C APP PRRC2A YTHDF2 PRRC2B

3.20e-07146627int:CPEB1
InteractionCNOT1 interactions

ANXA2R TNRC6A TNRC6B CEP152 TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

3.72e-07305629int:CNOT1
InteractionUNK interactions

SLC4A7 SF3B1 TNRC6A TNRC6B ZFYVE19 TNRC6C PRRC2A PICALM YTHDF2 PRRC2B

4.36e-074086210int:UNK
InteractionCEP85 interactions

TNRC6A TNRC6B CEP152 TNRC6C PRRC2A YTHDF2 PRRC2B

8.59e-07169627int:CEP85
InteractionHELZ interactions

CHIA TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

1.17e-06257628int:HELZ
InteractionAGO1 interactions

TNRC6A TNRC6B TNRC6C APP TRIM24 PRRC2A YTHDF2

1.46e-06183627int:AGO1
InteractionSMAP2 interactions

DAB2 TNRC6B TNRC6C PRRC2A PICALM YTHDF2 PRRC2B

1.82e-06189627int:SMAP2
InteractionTNRC6B interactions

TNRC6A TNRC6B CEP152 TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

2.34e-06282628int:TNRC6B
InteractionFAM184A interactions

PLEKHG1 TNRC6A TNRC6B TNRC6C APP

2.79e-0672625int:FAM184A
InteractionR3HDM2 interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

2.80e-06129626int:R3HDM2
InteractionTNRC6C interactions

TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2

4.15e-06138626int:TNRC6C
InteractionCNOT10 interactions

TNRC6A TNRC6B CEP152 TNRC6C PRRC2A YTHDF2

4.70e-06141626int:CNOT10
InteractionANKRD17 interactions

TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

5.92e-06226627int:ANKRD17
InteractionAGO3 interactions

TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2

7.51e-06153626int:AGO3
InteractionLATS1 interactions

PLEKHG1 SF3B1 SVIL TNRC6A TNRC6B CEP152 TNRC6C APP MYBPC1

7.56e-06440629int:LATS1
InteractionCPEB4 interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

8.40e-06156626int:CPEB4
InteractionODF2 interactions

PLEKHG1 SVIL TNRC6A TNRC6B TNRC6C APP

9.03e-06158626int:ODF2
InteractionEIF4E2 interactions

TNRC6A TNRC6B TNRC6C APP HDAC7 PRRC2A YTHDF2

1.03e-05246627int:EIF4E2
InteractionPRRC2B interactions

TNRC6A TNRC6B APP PRRC2A PICALM YTHDF2 PRRC2B

1.67e-05265627int:PRRC2B
InteractionRNF214 interactions

TNRC6B CEP152 PICALM YTHDF2 PRRC2B

1.70e-05104625int:RNF214
InteractionCEP135 interactions

PLEKHG1 C2CD3 TNRC6A TNRC6B CEP152 TNRC6C PRRC2B

1.97e-05272627int:CEP135
InteractionANKHD1-EIF4EBP3 interactions

TNRC6A TNRC6B PRRC2A YTHDF2 PRRC2B

2.04e-05108625int:ANKHD1-EIF4EBP3
InteractionCNOT11 interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2

2.44e-05112625int:CNOT11
InteractionSTIL interactions

PLEKHG1 C2CD3 TNRC6A TNRC6B CEP152 TNRC6C

2.57e-05190626int:STIL
InteractionCNOT6 interactions

TNRC6A TNRC6B TNRC6C YTHDF2

2.65e-0556624int:CNOT6
InteractionFAM120C interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

2.65e-05191626int:FAM120C
InteractionCEP192 interactions

TNRC6A TNRC6B CEP152 TNRC6C PRRC2A PRRC2B

2.73e-05192626int:CEP192
InteractionPUM1 interactions

TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

2.78e-05287627int:PUM1
InteractionCFHR2 interactions

CFHR1 APP

2.79e-053622int:CFHR2
InteractionAGO4 interactions

TNRC6A TNRC6B TNRC6C APP TRIM24

3.13e-05118625int:AGO4
InteractionFUBP3 interactions

TNRC6A TNRC6B TNRC6C APP PRRC2A YTHDF2 PRRC2B

3.46e-05297627int:FUBP3
InteractionUBAP2L interactions

SF3B1 TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

3.53e-05298627int:UBAP2L
InteractionAP2A1 interactions

SF3B1 TNRC6A DAB2 TNRC6B TNRC6C APP PICALM

3.61e-05299627int:AP2A1
InteractionSAMD4B interactions

PLEKHG1 TNRC6B CEP152 YTHDF2 PRRC2B

3.68e-05122625int:SAMD4B
InteractionNUP35 interactions

PCF11 WDR33 TNRC6A TNRC6B TRIM24 JMJD1C YTHDF2 PRRC2B

4.50e-05424628int:NUP35
InteractionSEC16A interactions

PSMF1 WDR33 TNRC6A TNRC6B TNRC6C PRRC2A PICALM PRRC2B

4.65e-05426628int:SEC16A
InteractionRNF43 interactions

EXPH5 SVIL TNRC6A TNRC6B TRIM24 PICALM JMJD1C PRRC2B

4.73e-05427628int:RNF43
InteractionYTHDF2 interactions

TNRC6A TNRC6B TNRC6C APP PRRC2A YTHDF2 PRRC2B

4.73e-05312627int:YTHDF2
InteractionCNOT4 interactions

TNRC6A TNRC6B TRIM24 YTHDF2

4.78e-0565624int:CNOT4
InteractionZC3H7A interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

5.14e-05215626int:ZC3H7A
InteractionMEX3B interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

6.14e-05222626int:MEX3B
InteractionKIZ interactions

TNRC6A TNRC6B TNRC6C

7.69e-0527623int:KIZ
InteractionNINL interactions

PLEKHG1 SVIL TNRC6A TNRC6B COBL CEP152 TNRC6C PRRC2B

7.72e-05458628int:NINL
InteractionCNOT8 interactions

TNRC6A TNRC6B TNRC6C YTHDF2

7.95e-0574624int:CNOT8
InteractionPUM2 interactions

TNRC6B TRIM24 PRRC2A YTHDF2 PRRC2B

8.10e-05144625int:PUM2
InteractionDAZL interactions

TNRC6A TNRC6B PRRC2A YTHDF2 PRRC2B

8.37e-05145625int:DAZL
InteractionGSK3A interactions

WDR33 TNRC6A DAB2 TNRC6B COBL CEP152 APP PICALM

8.45e-05464628int:GSK3A
InteractionCTIF interactions

TNRC6B TNRC6C PRRC2A YTHDF2

9.29e-0577624int:CTIF
InteractionEYA4 interactions

WDR33 TNRC6A TNRC6B TNRC6C JMJD1C PRRC2B

1.01e-04243626int:EYA4
InteractionYTHDF3 interactions

TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

1.08e-04246626int:YTHDF3
InteractionNIN interactions

PLEKHG1 C2CD3 SVIL TNRC6A TNRC6B CEP152 YTHDF2

1.14e-04359627int:NIN
InteractionBICD1 interactions

PLEKHG1 C2CD3 CALD1 TNRC6A TNRC6B TNRC6C

1.18e-04250626int:BICD1
InteractionSOX7 interactions

APP TRIM24 KDM6A JMJD1C

1.19e-0482624int:SOX7
InteractionAP2B1 interactions

TNRC6A DAB2 TNRC6B CEP152 TNRC6C APP PICALM

1.44e-04373627int:AP2B1
InteractionSPATA2 interactions

TNRC6A TNRC6B TNRC6C APP

1.49e-0487624int:SPATA2
InteractionDCP1A interactions

TNRC6A TNRC6B TNRC6C TRIM24 YTHDF2

1.58e-04166625int:DCP1A
InteractionMIF interactions

ASXL1 TNRC6A TNRC6B MCM4 TNRC6C TRIM24

1.59e-04264626int:MIF
InteractionLZTS2 interactions

PLEKHG1 RTP5 WDR33 EXPH5 TNRC6A TNRC6B CEP152 TNRC6C

1.67e-04512628int:LZTS2
InteractionTNKS1BP1 interactions

ANXA2R TNRC6A TNRC6B TRIM24 YTHDF2

1.67e-04168625int:TNKS1BP1
InteractionMKRN2 interactions

TNRC6A TNRC6B TNRC6C APP PRRC2A YTHDF2 PRRC2B

1.75e-04385627int:MKRN2
InteractionPRRC2A interactions

PSMF1 TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2 PRRC2B

1.87e-04389627int:PRRC2A
InteractionAR interactions

PCF11 ASXL1 SF3B1 WDR33 EXPH5 SVIL TRIM24 KDM6A HDAC7 JMJD1C PRRC2B

1.97e-049926211int:AR
InteractionMPHOSPH9 interactions

SVIL TNRC6A TNRC6B TNRC6C

2.10e-0495624int:MPHOSPH9
InteractionSMC5 interactions

PCF11 SF3B1 CALD1 WDR33 MCM4 TRIM24 HDAC7 PRRC2A PICALM JMJD1C YTHDF2

2.11e-0410006211int:SMC5
InteractionPAN2 interactions

CALD1 SVIL TNRC6A TNRC6B TNRC6C PRRC2A YTHDF2

2.11e-04397627int:PAN2
InteractionGIGYF1 interactions

TNRC6A TNRC6B TNRC6C HDAC7 YTHDF2

2.13e-04177625int:GIGYF1
InteractionPATL1 interactions

TNRC6A TNRC6B APP YTHDF2 PRRC2B

2.13e-04177625int:PATL1
InteractionTBK1 interactions

PSMF1 TNRC6A TNRC6B CEP152 TNRC6C APP TF

2.28e-04402627int:TBK1
InteractionRBFOX2 interactions

ASXL1 PSMF1 CALD1 TNRC6A PRRC2A PRRC2B

2.36e-04284626int:RBFOX2
InteractionGLI3 interactions

TNRC6A TNRC6B YTHDF2 PRRC2B

2.36e-0498624int:GLI3
InteractionQKI interactions

PSMF1 CALD1 TNRC6A APP PRRC2B

2.96e-04190625int:QKI
InteractionKCNA3 interactions

CALD1 EXPH5 CAPRIN2 AKNAD1 TNRC6B COBL MCM4 PRRC2A JMJD1C YTHDF2

3.01e-048716210int:KCNA3
InteractionEIF4ENIF1 interactions

TNRC6A TNRC6B TRIM24 PRRC2A YTHDF2 PRRC2B

3.16e-04300626int:EIF4ENIF1
InteractionPOMZP3 interactions

APP PRRC2A

3.31e-049622int:POMZP3
InteractionMYO18A interactions

CALD1 SVIL DAB2 COBL HDAC7 PICALM

3.33e-04303626int:MYO18A
InteractionLIMA1 interactions

CALD1 SVIL DAB2 COBL APP HDAC7 PICALM

3.38e-04429627int:LIMA1
InteractionAMOT interactions

PLEKHG1 TNRC6A TNRC6B CEP152 APP MYBPC1

3.89e-04312626int:AMOT
InteractionC10orf88 interactions

TNRC6B TNRC6C APP PICALM

4.07e-04113624int:C10orf88
InteractionRBM47 interactions

TNRC6B PRRC2A PICALM YTHDF2 PRRC2B

4.10e-04204625int:RBM47
InteractionRBMS1 interactions

TNRC6A TNRC6B PRRC2A YTHDF2 PRRC2B

4.38e-04207625int:RBMS1
InteractionSEZ6L interactions

APP TRIM24

5.03e-0411622int:SEZ6L
InteractionZNF449 interactions

ZSCAN20 APP

5.03e-0411622int:ZNF449
InteractionZYX interactions

SVIL TNRC6A TNRC6B COBL CEP152 YTHDF2

5.15e-04329626int:ZYX
InteractionDTX2 interactions

PCF11 SLC4A7 WDR33 TNRC6A DAB2 JMJD1C

5.24e-04330626int:DTX2
InteractionPXN interactions

SELE PLEKHG1 TNRC6A TNRC6B CEP152 PICALM

5.58e-04334626int:PXN
InteractionAGO2 interactions

TNRC6A TNRC6B TNRC6C TRIM24 PRRC2A YTHDF2 PRRC2B

5.98e-04472627int:AGO2
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6A TNRC6B TNRC6C

1.62e-0525363775
GeneFamilyPHD finger proteins|Lysine demethylases

KDM6A JMJD1C

1.03e-0324362485
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELE CFHR1

5.74e-03573621179
CoexpressionGSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP

PLEKHG1 EDEM3 C2CD3 SVIL TNRC6B APP

8.66e-06200636M8500
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

CALD1 SVIL APP JMJD1C LDB2

2.00e-05137635M39241
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 PIK3C2G ANXA2R SCG3 PKHD1L1 TF

2.05e-07179636ec1d7017da325647b629de703135a404bbdc627d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG1 CALD1 SPHKAP APP PKHD1L1 LDB2

2.19e-07181636e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG1 CALD1 SPHKAP APP PKHD1L1 LDB2

2.57e-0718663620340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PLEKHG1 CALD1 AKNAD1 PKHD1L1 LDB2

4.65e-06173635a81992965137195d20fc498f750975303961a828
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 CALD1 APP PKHD1L1 LDB2

5.06e-0617663598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 CALD1 APP PKHD1L1 LDB2

5.06e-06176635c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell356C-Endothelial_cells-Endothelial-D|356C / Donor, Lineage, Cell class and subclass (all cells)

SELE PLEKHG1 CALD1 APP LDB2

5.20e-06177635a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCell356C-Endothelial_cells-Endothelial-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

SELE PLEKHG1 CALD1 APP LDB2

5.20e-06177635ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SELE PLEKHG1 APP JMJD1C LDB2

5.50e-06179635754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 SCG3 APP PKHD1L1 LDB2

6.28e-0618463515cbddea9efb2346a2028d77edfe9ba32923568f
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 SCG3 APP PKHD1L1 LDB2

6.28e-061846350087c605c161fd8a39aa394f51994a04e8353bf1
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 SCG3 APP PKHD1L1 LDB2

6.28e-06184635968afa6b5ba84169377a24c150bb68749fa674d9
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 SCG3 APP PKHD1L1 LDB2

6.28e-06184635920f95625978132c2b6c76654ef6298244103e2d
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

PLEKHG1 CALD1 EXPH5 APP LDB2

6.28e-061846355f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 SLC4A7 APP JMJD1C LDB2

6.45e-06185635673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCG3 SPHKAP AKNAD1 F5 GRP

6.62e-061866352fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCG3 SPHKAP AKNAD1 F5 GRP

6.62e-06186635ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 PIK3C2G SCG3 PKHD1L1 GRP

6.62e-061866359579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCG3 SPHKAP AKNAD1 F5 GRP

6.62e-06186635714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCellASK428-Endothelial-Lymphatic|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CALD1 SCG3 APP PKHD1L1 LDB2

6.97e-06188635c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 CALD1 APP PKHD1L1 LDB2

6.97e-06188635aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|normal_Lung / Location, Cell class and cell subclass

CALD1 SCG3 APP PKHD1L1 LDB2

7.34e-061906352185db6007404a2b22325f91460dd17635be9bba
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

PLEKHG1 CALD1 APP PKHD1L1 LDB2

7.34e-0619063591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 DAB2 APP HDAC7 LDB2

7.53e-061916351924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 DAB2 APP HDAC7 LDB2

7.53e-0619163588f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 TNRC6A TNRC6B TRIM24 KDM6A

7.72e-06192635916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

PLEKHG1 CALD1 APP PKHD1L1 LDB2

7.92e-0619363568eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCellCOPD-Endothelial-Lymphatic|COPD / Disease state, Lineage and Cell class

PLEKHG1 CALD1 APP PKHD1L1 LDB2

7.92e-0619363518bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

7.92e-061936359ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

PLEKHG1 CALD1 APP PKHD1L1 LDB2

7.92e-06193635093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 TNRC6A TNRC6B TRIM24 KDM6A

7.92e-06193635e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELE PLEKHG1 ANXA2R DAB2 LDB2

7.92e-061936350f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PLEKHG1 SLC4A7 APP JMJD1C LDB2

7.92e-06193635479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.12e-06194635f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.12e-061946353b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

8.12e-061946359591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.12e-061946355d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellControl-Endothelial|Control / Disease state, Lineage and Cell class

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

8.12e-06194635485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.33e-06195635094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellEndothelial|World / Lineage, Cell type, age group and donor

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.54e-0619663596c6d78482a130ce4e29f6629972a06d10d7530e
ToppCellproximal-Endothelial-Lymphatic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 SCG3 APP PKHD1L1 LDB2

8.75e-061976358835961bd734a86063fd854cd2fb7028aefb7a72
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Endothelial-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

8.75e-06197635f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCellproximal-Endothelial-Lymphatic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 SCG3 APP PKHD1L1 LDB2

8.75e-061976358d79e747e344656e2bfc7fe872b4430dca941196
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

8.75e-06197635b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.75e-06197635ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

8.75e-061976351a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCG3 SPHKAP AKNAD1 F5 GRP

8.75e-061976353a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCell356C-Endothelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

SELE PLEKHG1 CALD1 APP LDB2

8.75e-06197635f20eda534b2b28986790b28ce150ca3ba067593a
ToppCellproximal-3-Endothelial-Lymphatic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 SCG3 APP PKHD1L1 LDB2

8.75e-061976351c64e4eb9bfbaf5d6b4349642858f83a00d4d4c6
ToppCell390C-Endothelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

SELE PLEKHG1 CALD1 APP LDB2

8.75e-06197635aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

8.75e-0619763596d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.97e-061986359ab0db78394e730f6866b2db80047149024ad5f6
ToppCelldistal-1-Endothelial-Bronchial_Vessel_1|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELE PLEKHG1 CALD1 APP LDB2

8.97e-061986355cd81fe1a21c0e1a7f0d5a62ddf8e422b05aedc7
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.97e-06198635b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.97e-06198635fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CALD1 APP PKHD1L1 LDB2

8.97e-06198635e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellParenchymal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CALD1 APP PKHD1L1 LDB2

9.19e-06199635a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCellBiopsy_Other_PF-Endothelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

SELE PLEKHG1 CALD1 APP LDB2

9.41e-06200635f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCellParenchymal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 CALD1 APP PKHD1L1 LDB2

9.41e-062006350e648e9eb96c83a94505d07323785a7a40997eb0
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 CALD1 APP PKHD1L1 LDB2

9.41e-06200635f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLEKHG1 CALD1 APP PKHD1L1 LDB2

9.41e-06200635e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PLEKHG1 CALD1 APP PKHD1L1 LDB2

9.41e-062006354ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCellBiopsy_Other_PF-Endothelial-Endothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

SELE PLEKHG1 CALD1 APP LDB2

9.41e-0620063540d57a383c79d3365e033d08efd9371f0bc5bf55
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 CALD1 EXPH5 APP LDB2

9.41e-062006357a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCellBronchial-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SELE PLEKHG1 CALD1 PKHD1L1 LDB2

9.41e-06200635ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3C2G AKNAD1 BCAS1 TF

3.91e-0513463464979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 SCG3 APP LDB2

7.79e-05160634958256e3d3836160763b82bb48f794087918d935
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EXPH5 SCG3 F5 CFAP65

8.18e-05162634f2a87019ff9b466617e90c60d182ab7d14581cc9
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

SELE CALD1 APP LDB2

8.37e-05163634977a970b1296234c22178420294cea73506ee02f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SELE CALD1 APP LDB2

8.37e-05163634ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELE CALD1 SPHKAP MYBPC1

9.41e-05168634435ef2e4d702e978d54f9d1f5a047f39c691cc63
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 APP PKHD1L1 LDB2

9.63e-05169634987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

PLEKHG1 CALD1 COBL LDB2

9.85e-05170634e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

DAB2 COBL STOX1 APP

1.01e-04171634779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

DAB2 COBL STOX1 APP

1.01e-04171634debbb071d260639b16269c94d172766908325c58
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SCG3 SPHKAP F5 GRP

1.01e-04171634f4321133190a3df9d31f5d4021a464d3840145f1
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SCG3 SPHKAP F5 GRP

1.01e-04171634ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CALD1 APP PKHD1L1 LDB2

1.03e-04172634d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SCG3 SPHKAP F5 GRP

1.03e-04172634d0cdedd734406988a9a93d7300c7b1a8b4b45c38
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ANXA2R SCG3 PKHD1L1 LDB2

1.03e-04172634c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

PLEKHG1 CALD1 AKNAD1 PKHD1L1

1.03e-041726348a527dff06d841a86c7eb04a1dd9630787294da4
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

SELE PLEKHG1 CALD1 LDB2

1.03e-04172634c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ADGRE2 HDAC7 LDB2 CFAP65

1.08e-04174634b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF469 PIK3C2G GRP LDB2

1.08e-041746349cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

SELE CALD1 PKHD1L1 LDB2

1.08e-041746342dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

SCG3 SPHKAP F5 GRP

1.10e-041756344db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

SCG3 SPHKAP F5 GRP

1.10e-041756348d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3C2G SCG3 PKHD1L1 LDB2

1.13e-041766345d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

SELE CALD1 PKHD1L1 LDB2

1.13e-04176634043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

EDEM3 DAB2 STOX1 ADGRE2

1.15e-0417763443e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 SCG3 PKHD1L1 LDB2

1.15e-04177634b1775e05c28883a15c56628028770bc59d3233fb
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCG3 APP PKHD1L1 LDB2

1.18e-041786344b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

PLEKHG1 CALD1 PKHD1L1 LDB2

1.18e-04178634c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG1 CALD1 APP PKHD1L1

1.18e-04178634ad3de3e03a401dac64431a541899445262246347
ToppCellCOVID-19_Convalescent-PLT_1|World / Disease Group and Platelet Clusters

DAB2 TNRC6C LINC02915 C18orf32

1.20e-04179634d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 PIK3C2G SCG3 PKHD1L1

1.20e-0417963440c65e8623547aeb80f9cd2366e29072467ce069
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

SCG3 SPHKAP F5 GRP

1.20e-04179634988d0853c391da1e5004f73f3678047418d3f6d3
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCG3 SPHKAP PKHD1L1 MYBPC1

1.20e-041796344135f9e8cd8494cbc189e5210dded84659643fb8
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 APP JMJD1C LDB2

1.23e-04180634493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 CALD1 APP LDB2

1.23e-04180634b043f9ffb9a4cd427a15bebb86a711c7b08866e8
DrugAztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A

EDEM3 ASXL1 SLC4A7 TNRC6B CEP152 PRRC2A

1.60e-051976262282_DN
Drug(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A

EDEM3 SLC4A7 CEP152 APP KDM6A HDAC7

1.60e-051976264363_DN
DrugNomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A

SLC4A7 SVIL MCM4 CEP152 APP HDAC7

1.64e-051986262062_DN
DrugGuanabenz acetate [23256-50-0]; Down 200; 13.8uM; HL60; HG-U133A

SLC4A7 EXPH5 APP POGLUT2 ADGRE2 PRRC2B

1.69e-051996262045_DN
DiseaseMYELODYSPLASTIC SYNDROME

ASXL1 SF3B1

4.19e-055612614286
DiseaseMyelodysplastic syndrome

ASXL1 SF3B1

4.19e-055612cv:C3463824
DiseaseMental deterioration

APP PICALM

1.50e-049612C0234985
DiseaseMild cognitive disorder

APP PICALM

1.50e-049612C1270972
DiseaseUterine leiomyoma, estrogen-receptor negative breast cancer

EXPH5 TNRC6B

1.87e-0410612EFO_1000650, HP_0000131
DiseaseImpaired cognition

APP PICALM

3.76e-0414612C0338656
Diseasemyelodysplastic syndrome (implicated_via_orthology)

ASXL1 SF3B1

4.34e-0415612DOID:0050908 (implicated_via_orthology)
Diseasecortical thickness

PLEKHG1 ZNF469 SF3B1 TNRC6A TNRC6B STOX1 CAMTA1 LINC02915 JMJD1C

4.45e-041113619EFO_0004840
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

F5 JMJD1C

4.95e-0416612EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseasebody fat percentage

EDEM3 SPHKAP TNRC6A CAMTA1 PRRC2A PRRC2B

5.10e-04488616EFO_0007800
DiseaseAmnesia

APP GRP

5.60e-0417612C0002622
DiseaseTactile Amnesia

APP GRP

5.60e-0417612C0750906
DiseaseAmnestic State

APP GRP

5.60e-0417612C0750907
DiseaseDissociative Amnesia

APP GRP

5.60e-0417612C0236795
DiseaseGlobal Amnesia

APP GRP

5.60e-0417612C0262497
DiseaseHysterical amnesia

APP GRP

5.60e-0417612C0233750
DiseaseAlzheimer disease, psychotic symptoms

TNRC6C PICALM

5.60e-0417612EFO_0005940, MONDO_0004975
DiseaseTemporary Amnesia

APP GRP

5.60e-0417612C0233796
Diseaseacute myeloid leukemia (is_implicated_in)

CFHR1 ASXL1 PICALM

7.11e-0484613DOID:9119 (is_implicated_in)
Diseaseprothrombin time measurement

F5 JMJD1C

8.61e-0421612EFO_0008390
Diseaseplatelet component distribution width

SLC4A7 SVIL CAMTA1 HDAC7 PRRC2A JMJD1C MYBPC1

9.18e-04755617EFO_0007984
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

EDEM3 SPHKAP TNRC6A CAMTA1 PRRC2A

9.39e-04364615EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseAcute Confusional Senile Dementia

APP TF PICALM

1.14e-0399613C0546126
DiseaseAlzheimer's Disease, Focal Onset

APP TF PICALM

1.14e-0399613C0750900
DiseaseAlzheimer Disease, Early Onset

APP TF PICALM

1.14e-0399613C0750901
DiseasePresenile dementia

APP TF PICALM

1.14e-0399613C0011265
DiseaseAlzheimer Disease, Late Onset

APP TF PICALM

1.14e-0399613C0494463
Diseasemean platelet volume

PCDHGA1 SVIL TNRC6A BCAS1 CAMTA1 HDAC7 PICALM JMJD1C

1.15e-031020618EFO_0004584
DiseaseFamilial Alzheimer Disease (FAD)

APP TF PICALM

1.18e-03100613C0276496
DiseaseAlzheimer's Disease

APP TF PICALM

1.21e-03101613C0002395
Diseasepre-eclampsia (is_implicated_in)

STOX1 F5

1.22e-0325612DOID:10591 (is_implicated_in)
Diseasemean reticulocyte volume

ZNF469 SCG3 MCM4 BCAS1 HDAC7 JMJD1C LDB2

1.27e-03799617EFO_0010701
Diseaseinflammatory biomarker measurement

F5 JMJD1C

1.32e-0326612EFO_0004872
Diseaseneuroimaging measurement

PLEKHG1 ZNF469 TNRC6A TNRC6B CAMTA1 TF LINC02915 JMJD1C

1.55e-031069618EFO_0004346
DiseaseDevelopmental Academic Disorder

PDE1B APP

1.65e-0329612C1330966
DiseaseLearning Disorders

PDE1B APP

1.65e-0329612C0023186
DiseaseLearning Disturbance

PDE1B APP

1.65e-0329612C0751263
DiseaseAdult Learning Disorders

PDE1B APP

1.65e-0329612C0751262
DiseaseLearning Disabilities

PDE1B APP

1.65e-0329612C0751265
DiseaseHematopoetic Myelodysplasia

ASXL1 SF3B1

1.65e-0329612C2713368
Diseasecortical surface area measurement

PLEKHG1 ZNF469 SF3B1 TNRC6A TNRC6B STOX1 PRRC2A PICALM LINC02915

1.69e-031345619EFO_0010736
Diseasemyelodysplastic syndrome (is_implicated_in)

ASXL1 SF3B1

1.76e-0330612DOID:0050908 (is_implicated_in)
Diseaseblood pressure, chronic obstructive pulmonary disease

TNRC6A HDAC7

2.00e-0332612EFO_0000341, EFO_0004325

Protein segments in the cluster

PeptideGeneStartEntry
EKPKNQLWPESSTSD

CEP152

601

O94986
QASGSQPVGKWNSKD

CAMTA1

1311

Q9Y6Y1
RDPAWQKPQQKSEGA

CCDC88B

691

A6NC98
NVQNGKWDSDPSGTK

APP

46

P05067
LDWNQAQKSGDPGPS

ADGRE2

386

Q9UHX3
KNGATQGWDAPQEVP

CHIA

311

Q9BZP6
QWSQKEKTGERPANP

ACSM4

61

P0C7M7
AKPTEFSWPGTQKQQ

ANXA2R

86

Q3ZCQ2
GSSVDKDEKPNWNQS

ASXL1

1026

Q8IXJ9
SSANASKWSPPQNYK

ZFYVE19

136

Q96K21
WPKKAIQESNDTNKG

C18orf32

36

Q8TCD1
SEKPSVQSVKPWSDQ

MSANTD5

26

A0A3B3IT52
KPQNTNKECSWGSPI

PIK3C2G

116

O75747
KQEAQAGPWPFSSSQ

DAB2

356

P98082
AANPIESQWNPKKTT

MCM4

616

P33991
LPVPSSSWEDGKGKQ

CFAP65

1731

Q6ZU64
KAGEETLKNSQPPWD

JMJD1C

421

Q15652
DSNPNVSWGKKVQPI

EDEM3

896

Q9BZQ6
QPADENWDPTGTKKI

KDM6A

1006

O15550
PWNSKPPATQETKSE

LDB2

351

O43679
DSKSKNQPSFQWRQP

PDE1B

451

Q01064
PKALGNQQPSWDSED

GRP

101

P07492
TQKPLTEEAKNWAPG

SELE

86

P16581
KSAWDQPSLPEGNKN

EXPH5

1561

Q8NEV8
KSGTEPKENVENWQS

PCF11

576

O94913
GWSSPQTDQNKEPKS

C2CD3

2191

Q4AC94
GPQKSPLWEKNGSEN

COBL

451

O75128
NKNSWPKEQTPELTD

AKNAD1

156

Q5T1N1
EQDSKQPETPKSWEN

CAPRIN2

536

Q6IMN6
PLSEEGWKQKPNLNA

HDAC7

866

Q8WUI4
LNGNWTEPPQCKDST

CFHR1

191

Q03591
NKAPANKDPSESWTL

BCAS1

126

O75363
PNDKKSELLPAGWNN

PSMF1

46

Q92530
KKEPFSQQAPPNTDW

PCDHGA1

801

Q9Y5H4
KAPDPAWSANATKGN

RTP5

156

Q14D33
PSAKPSQWKREAVGN

SPHKAP

301

Q2M3C7
NTKANPGTNWGETLK

TNRC6C

646

Q9HCJ0
PPNPSNETLAQWKKD

SLC4A7

771

Q9Y6M7
VSWKPQDSSEQPQEK

SVIL

1081

O95425
AWGESTPLANKPGKQ

F5

981

P12259
WKKQNPGADTSAPTG

NKX1-1

351

Q15270
KDGTGWASKQEQSDP

PRRC2A

81

P48634
INEWLTKTPDGNKSP

CALD1

746

Q05682
AQKPQSPGWKNMSST

LINC02915

121

Q8N8G6
GTTKNDVNWSQPGEK

PICALM

556

Q13492
NSSNGKSEWLDPSQK

TRIM24

796

O15164
KPSNTSEKEQGPEFW

ZSCAN20

261

P17040
TGGKNPDPWAKNLNE

TF

561

P02787
TPKKLSSWDQAETPG

SF3B1

211

O75533
DTGKKPASWSQSPQN

STOX1

876

Q6ZVD7
PKDGTGWANKQDQQD

PRRC2B

81

Q5JSZ5
GWANKQDQQDPKSSS

PRRC2B

86

Q5JSZ5
SWDKNGSPNKQPSSE

PRRC2B

901

Q5JSZ5
TQDWALPEGPNQGAK

PKHD1L1

3136

Q86WI1
QANTGPPWESKNSTA

POGLUT2

291

Q6UW63
KPASTENGQWKGQAP

ZNF469

2426

Q96JG9
PLKIQKDGWASPQES

PLEKHG1

1051

Q9ULL1
SGSKDSQQPIKFWDP

WDR33

261

Q9C0J8
SQQPIKFWDPKTGQS

WDR33

266

Q9C0J8
PWTTDAKIQNKNCPG

ZNF614

66

Q8N883
NQEFPTGKVPNSWSK

ZNF235

171

Q14590
DPNKPTSWTENQAGK

SCG3

211

Q8WXD2
DSSKPVSSPDWNKQQ

TNRC6A

936

Q8NDV7
GTWDNKGPVAKAPSQ

YTHDF2

276

Q9Y5A9
EKTPSSWNENPSKDQ

TNRC6B

716

Q9UPQ9
PGKWTKNGLPVQESD

MYBPC1

461

Q00872