Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ASH	ASPM HYDIN	1.16e-05	2	64	2	IPR031549
Domain	ASH	ASPM HYDIN	1.16e-05	2	64	2	PF15780
Domain	EF-hand_Ca_insen	ACTN4 ACTN1	1.72e-04	6	64	2	IPR014837
Domain	EFhand_Ca_insen	ACTN4 ACTN1	1.72e-04	6	64	2	PF08726
Domain	AC_N	ADCY2 ADCY3	3.19e-04	8	64	2	IPR032628
Domain	Adcy	ADCY2 ADCY3	3.19e-04	8	64	2	IPR030672
Domain	AC_N	ADCY2 ADCY3	3.19e-04	8	64	2	PF16214
Domain	Diacylglycerol_kinase_cat_dom	CERKL DGKZ	1.18e-03	15	64	2	IPR001206
Domain	DAGK_cat	CERKL DGKZ	1.18e-03	15	64	2	PF00781
Domain	DAGK	CERKL DGKZ	1.18e-03	15	64	2	PS50146
Domain	CH	ASPM ACTN4 ACTN1	1.44e-03	65	64	3	SM00033
Domain	A/G_cyclase_CS	ADCY2 ADCY3	1.52e-03	17	64	2	IPR018297
Domain	NAD/diacylglycerol_kinase	CERKL DGKZ	1.52e-03	17	64	2	IPR016064
Domain	Nucleotide_cyclase	ADCY2 ADCY3	1.71e-03	18	64	2	IPR029787
Domain	-	ADCY2 ADCY3	1.71e-03	18	64	2	3.30.70.1230
Domain	CH	ASPM ACTN4 ACTN1	1.78e-03	70	64	3	PF00307
Domain	-	ASPM ACTN4 ACTN1	1.86e-03	71	64	3	1.10.418.10
Domain	GUANYLATE_CYCLASE_1	ADCY2 ADCY3	1.90e-03	19	64	2	PS00452
Domain	Guanylate_cyc	ADCY2 ADCY3	1.90e-03	19	64	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY2 ADCY3	1.90e-03	19	64	2	PS50125
Domain	A/G_cyclase	ADCY2 ADCY3	1.90e-03	19	64	2	IPR001054
Domain	CYCc	ADCY2 ADCY3	1.90e-03	19	64	2	SM00044
Domain	CH	ASPM ACTN4 ACTN1	2.01e-03	73	64	3	PS50021
Domain	CH-domain	ASPM ACTN4 ACTN1	2.17e-03	75	64	3	IPR001715
Domain	Actinin_actin-bd_CS	ACTN4 ACTN1	2.79e-03	23	64	2	IPR001589
Domain	Spectrin	ACTN4 ACTN1	2.79e-03	23	64	2	PF00435
Domain	ACTININ_2	ACTN4 ACTN1	2.79e-03	23	64	2	PS00020
Domain	ACTININ_1	ACTN4 ACTN1	2.79e-03	23	64	2	PS00019
Domain	Cadherin_cytoplasmic-dom	CDH4 CDH15	3.30e-03	25	64	2	IPR000233
Domain	Cadherin_C	CDH4 CDH15	3.30e-03	25	64	2	PF01049
Domain	Catenin_binding_dom	CDH4 CDH15	4.42e-03	29	64	2	IPR027397
Domain	Spectrin_repeat	ACTN4 ACTN1	4.42e-03	29	64	2	IPR002017
Domain	-	CDH4 CDH15	4.42e-03	29	64	2	4.10.900.10
Domain	Spectrin/alpha-actinin	ACTN4 ACTN1	5.37e-03	32	64	2	IPR018159
Domain	SPEC	ACTN4 ACTN1	5.37e-03	32	64	2	SM00150
Domain	Sc_DH/Rdtase_CS	HSD11B2 HSD11B1L	6.39e-03	35	64	2	IPR020904
Pathway	REACTOME_CELL_JUNCTION_ORGANIZATION	ACTN1 CDH4 ITGB4 SDK1 CDH15	5.18e-06	73	49	5	MM15126
Pathway	REACTOME_CELL_CELL_COMMUNICATION	ACTN4 ACTN1 CDH4 ITGB4 SDK1 CDH15	1.52e-05	155	49	6	M522
Pathway	REACTOME_CELL_CELL_COMMUNICATION	ACTN1 CDH4 ITGB4 SDK1 CDH15	1.98e-05	96	49	5	MM14592
Pathway	REACTOME_CELL_JUNCTION_ORGANIZATION	ACTN1 CDH4 ITGB4 SDK1 CDH15	5.15e-05	117	49	5	M19248
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	ACTN4 ACTN1 ITGB4	1.50e-04	30	49	3	M47724
Pubmed	Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.	ACTN4 ACTN1	3.44e-06	2	65	2	34010028
Pubmed	An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.	ACTN4 ACTN1	3.44e-06	2	65	2	23557398
Pubmed	Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.	ACTN4 ACTN1	3.44e-06	2	65	2	20037648
Pubmed	HAMLET binding to α-actinin facilitates tumor cell detachment.	ACTN4 ACTN1	3.44e-06	2	65	2	21408150
Pubmed	Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.	ACTN4 ACTN1	3.44e-06	2	65	2	28797528
Pubmed	α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.	ACTN4 ACTN1	3.44e-06	2	65	2	23454549
Pubmed	Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.	ACTN4 ACTN1	3.44e-06	2	65	2	20156433
Pubmed	Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.	ACTN4 ACTN1	1.03e-05	3	65	2	16751418
Pubmed	α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.	ACTN4 ACTN1	1.03e-05	3	65	2	21784188
Pubmed	Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.	ACTN4 ACTN1	1.03e-05	3	65	2	23890175
Pubmed	Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis.	ACTN4 ACTN1	1.03e-05	3	65	2	16951376
Pubmed	Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.	ACTN4 ACTN1	2.06e-05	4	65	2	23515331
Pubmed	Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.	ACTN4 ACTN1	2.06e-05	4	65	2	1629252
Pubmed	An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.	ACTN4 ACTN1	2.06e-05	4	65	2	2116421
Pubmed	Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.	ACTN4 ACTN1	2.06e-05	4	65	2	22351778
Pubmed	CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.	ACTN4 ACTN1	2.06e-05	4	65	2	10753915
Pubmed	Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.	ACTN4 ACTN1	2.06e-05	4	65	2	16807302
Pubmed	Interactions of a hemidesmosome component and actinin family members.	ACTN4 ACTN1	2.06e-05	4	65	2	11739652
Pubmed	Structural dynamics of alpha-actinin-vinculin interactions.	ACTN4 ACTN1	2.06e-05	4	65	2	15988023
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	UBR4 ACTN1 CDH4 ITGB4 ADCY3 DYNC1H1	3.14e-05	322	65	6	26514267
Pubmed	Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.	ACTN4 ACTN1	3.43e-05	5	65	2	15841212
Pubmed	Mammalian adenylyl cyclase family members are randomly located on different chromosomes.	ADCY2 ADCY3	3.43e-05	5	65	2	7959689
Pubmed	The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.	ACTN4 ACTN1	3.43e-05	5	65	2	12837758
Pubmed	Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.	ACTN4 ACTN1	3.43e-05	5	65	2	19943616
Pubmed	The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.	ACTN4 ACTN1	3.43e-05	5	65	2	16501493
Pubmed	Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.	ACTN4 ACTN1	5.13e-05	6	65	2	18425115
Pubmed	The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.	ACTN4 ACTN1	5.13e-05	6	65	2	22693585
Pubmed	Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse.	ADCY2 ADCY3	5.13e-05	6	65	2	7766992
Pubmed	The protein-tyrosine phosphatase SHP-1 regulates the phosphorylation of alpha-actinin.	ACTN4 ACTN1	5.13e-05	6	65	2	15070900
Pubmed	Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.	ADCY2 ADCY3	5.13e-05	6	65	2	11549699
Pubmed	Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.	ACTN4 ACTN1	7.18e-05	7	65	2	11724819
Pubmed	Differential expression of adenylyl cyclase mRNAs in lacrimal glands of NZB/NZW and NOD pre-autoimmune mice.	ADCY2 ADCY3	7.18e-05	7	65	2	12613887
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	UBR4 ACTN4 ACTN1 PC DYNC1H1	8.01e-05	235	65	5	28378594
Pubmed	Mice deficient in alpha-actinin-4 have severe glomerular disease.	ACTN4 ACTN1	9.56e-05	8	65	2	12782671
Pubmed	CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.	ACTN4 ACTN1	9.56e-05	8	65	2	20215401
Pubmed	RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.	ACTN1 MAP3K1	9.56e-05	8	65	2	14581471
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	ACTN4 ACTN1 DYNC1H1	1.08e-04	49	65	3	21362503
Pubmed	Identification of novel germline polymorphisms governing capecitabine sensitivity.	SH2D4B ADCY2	1.23e-04	9	65	2	22864933
Pubmed	Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.	ADCY2 ADCY3	1.23e-04	9	65	2	9417641
Pubmed	Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.	ADCY2 ADCY3	1.23e-04	9	65	2	12503609
Pubmed	Role of the calcium modulated cyclases in the development of the retinal projections.	ADCY2 ADCY3	1.23e-04	9	65	2	17229090
Pubmed	Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN.	RBPJ ITGB4	1.23e-04	9	65	2	25016959
Pubmed	Purification and characterization of a soluble form of mammalian adenylyl cyclase.	ADCY2 ADCY3	1.53e-04	10	65	2	8663304
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY2 ADCY3	1.53e-04	10	65	2	16615126
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	ACTN4 ACTN1	1.53e-04	10	65	2	20368620
Pubmed	Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.	ADCY2 ADCY3	1.53e-04	10	65	2	11884542
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SACS DGKZ ACTN4 ACTN1 DYNC1H1	1.85e-04	281	65	5	28706196
Pubmed	Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.	ADCY2 ADCY3	1.87e-04	11	65	2	11299302
Pubmed	Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.	ADCY2 ADCY3	1.87e-04	11	65	2	10089566
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	ADCY2 ADCY3	1.87e-04	11	65	2	10808179
Pubmed	HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.	ADCY2 ADCY3	2.24e-04	12	65	2	10807185
Pubmed	Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.	ACTN4 ACTN1	2.24e-04	12	65	2	15465019
Pubmed	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	MDM1 BRWD1	2.65e-04	13	65	2	22365631
Pubmed	Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.	ACTN4 ACTN1	2.65e-04	13	65	2	28079882
Pubmed	Thirteen genes (Cebpb, E2f1, Tcf4, Cyp24, Pck1, Acra4, Edn3, Kcnb1, Mc3r, Ntsr, Cd40, Plcg1 and Rcad) that probably lie in the distal imprinting region of mouse chromosome 2 are not monoallelically expressed.	CDH4 CHRNA4	3.08e-04	14	65	2	7781998
Pubmed	Mechanical regulation of glycolysis via cytoskeleton architecture.	ACTN4 ACTN1	3.08e-04	14	65	2	32051585
Pubmed	Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.	ADCY2 ADCY3	3.08e-04	14	65	2	14993377
Pubmed	Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.	ACTN4 ACTN1	3.56e-04	15	65	2	11440986
Pubmed	Mechanism of GTP hydrolysis by G-protein alpha subunits.	ADCY2 ADCY3	3.56e-04	15	65	2	7937899
Pubmed	cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes.	ADCY2 ADCY3	3.56e-04	15	65	2	2165385
Pubmed	IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.	ELP3 DYNC1H1	3.56e-04	15	65	2	18303054
Pubmed	Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.	CEPT1 WDR33 PC ITGB4	3.83e-04	182	65	4	32239614
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY2 ADCY3	4.06e-04	16	65	2	17567809
Pubmed	Cadherin expression in the developing mouse olfactory system.	CDH4 CDH15	4.06e-04	16	65	2	17278136
Pubmed	Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins.	ACTN4 ACTN1	4.06e-04	16	65	2	16944923
Pubmed	Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.	ACTN4 ACTN1	4.06e-04	16	65	2	35390516
Pubmed	Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.	ITGB4 ADCY3	4.06e-04	16	65	2	21067603
Pubmed	Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on Notch signals.	RBPJ CDH15	4.59e-04	17	65	2	22940113
Pubmed	Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.	GALNT14 INTS8	4.59e-04	17	65	2	25102180
Pubmed	Luzp4 defines a new mRNA export pathway in cancer cells.	NXF2 ACTN4 ACTN1	4.62e-04	80	65	3	25662211
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	SACS WDR81 HYDIN	4.62e-04	80	65	3	19389623
Pubmed	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.	UBR4 ASPM DYNC1H1	5.33e-04	84	65	3	29563501
Pubmed	Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.	GALNT14 PC	6.39e-04	20	65	2	22174851
Pubmed	E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.	CDH4 CDH15	6.39e-04	20	65	2	7806582
Pubmed	Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.	ACTN4 ACTN1	7.06e-04	21	65	2	12202484
Pubmed	Canonical notch signaling functions as a commitment switch in the epidermal lineage.	RBPJ ITGB4	7.06e-04	21	65	2	17079689
Pubmed	AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis.	RBPJ ITGB4	7.06e-04	21	65	2	18824566
Pubmed	Proteomic identification of the TRAF6 regulation of vacuolar ATPase for osteoclast function.	ACTN4 ACTN1	7.06e-04	21	65	2	16196101
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	PTPRF UBR4 ACTN4 ELP3 INTS8 DYNC1H1	7.07e-04	573	65	6	28330616
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	UBR4 WDR81 ACTN4 ACTN1 PC HYDIN DYNC1H1	7.64e-04	807	65	7	30575818
Pubmed	Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis.	IBA57 CEPT1 ACTN4 ACTN1	7.93e-04	221	65	4	31796584
Pubmed	Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.	RBPJ ITGB4	8.48e-04	23	65	2	24337118
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	UBR4 ACTN4 ACTN1 DYNC1H1 BRWD1	9.10e-04	399	65	5	37536630
Pubmed	Gene network analysis in a pediatric cohort identifies novel lung function genes.	CERKL WDR33	9.24e-04	24	65	2	24023788
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	PTPRF ACTN4 ACTN1 ITGB4 DYNC1H1	1.11e-03	417	65	5	19199708
Pubmed	Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.	ACTN4 ACTN1	1.17e-03	27	65	2	36899856
Pubmed	Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.	ACTN4 ACTN1 DYNC1H1	1.20e-03	111	65	3	21163940
Pubmed	Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.	CDH4 PDZD2	1.26e-03	28	65	2	24322204
Pubmed	Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice.	ACTN4 PC	1.26e-03	28	65	2	30947518
Pubmed	Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.	UBR4 DYNC1H1	1.26e-03	28	65	2	35227662
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	DGKZ ACTN4 ACTN1 PC ELP3	1.27e-03	430	65	5	32581705
Pubmed	Proteomic profiling of Myc-associated proteins.	RBPJ SDK1 PDZD2	1.29e-03	114	65	3	21150319
Pubmed	The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.	ITGB4 MAP3K1	1.35e-03	29	65	2	19094228
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	ACTN4 ACTN1 DYNC1H1	1.43e-03	118	65	3	27377895
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	TSEN34 ACTN4 TYSND1 DYNC1H1	1.53e-03	264	65	4	32814769
Pubmed	Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.	SACS ASPM	1.54e-03	31	65	2	27798109
Pubmed	E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1.	ACTN4 ACTN1	1.54e-03	31	65	2	33777788
Pubmed	Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.	ACTN4 ACTN1	1.54e-03	31	65	2	14630798
Pubmed	Glucagon and regulation of glucose metabolism.	ADCY2 ADCY3	1.54e-03	31	65	2	12626323
Pubmed	ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.	RBPJ ITGB4	1.54e-03	31	65	2	22274697
GeneFamily	Actinins	ACTN4 ACTN1	3.79e-05	4	46	2	1112
GeneFamily	CD molecules\|Type I classical cadherins	CDH4 CDH15	6.30e-05	5	46	2	1185
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY2 ADCY3	2.81e-04	10	46	2	53
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 CERKL NHS HYDIN PDZD2	4.19e-06	164	65	5	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLI1 FAM110D ITGB4 SH2D4B SDK1	5.29e-06	172	65	5	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 ADCY2 HYDIN	7.73e-06	186	65	5	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 HYDIN MAP3K1	8.79e-06	191	65	5	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGPP1 HSD11B2 SLC14A2 SH2D4B	8.60e-05	159	65	4	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SGPP1 SLC41A1 SDK1 RETREG3	1.04e-04	167	65	4	b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT14 NHS SDK1 HYDIN	1.06e-04	168	65	4	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SGPP1 HSD11B2 SLC14A2 SDK1	1.09e-04	169	65	4	0332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 MDM1 DGKZ ACTN1	1.14e-04	171	65	4	355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GALNT14 NHS SDK1 HYDIN	1.33e-04	178	65	4	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CERKL ACTN1 SEC14L5 PDZD2	1.36e-04	179	65	4	9ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	NHS ACTN1 SDK1 ADCY3	1.36e-04	179	65	4	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDR81 SDK1 ADCY2 PDZD2	1.36e-04	179	65	4	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLI1 HUS1B FAM110D ITGB4	1.42e-04	181	65	4	72c28baf4fd417ff4a7068603830d55074960144
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLI1 HUS1B FAM110D ITGB4	1.42e-04	181	65	4	2ac4d3e8987d5a009d7908d8787e18165826202a
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLI1 HUS1B FAM110D ITGB4	1.42e-04	181	65	4	2628c7ac345eaaeecf8e34617e81948925962cb9
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	GALNT14 NHS HYDIN LYG1	1.51e-04	184	65	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FLI1 FAM110D ITGB4 PDZD2	1.51e-04	184	65	4	7e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 PTPRF SLC41A1 ITGB4	1.57e-04	186	65	4	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132E MDM1 ASPM INTS8	1.57e-04	186	65	4	3993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 HYDIN MAP3K1 LYG1	1.57e-04	186	65	4	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM132E MDM1 ASPM INTS8	1.57e-04	186	65	4	ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS HYDIN PDZD2	1.57e-04	186	65	4	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 HYDIN	1.57e-04	186	65	4	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 TMEM132E NHS PDZD2	1.57e-04	186	65	4	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS HYDIN PDZD2	1.60e-04	187	65	4	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NHS CDH4 SDK1 CHRNA4	1.60e-04	187	65	4	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS HYDIN PDZD2	1.64e-04	188	65	4	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 FAM110D ACTN4 ACTN1	1.67e-04	189	65	4	d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SGPP1 HSD11B2 SLC14A2 SDK1	1.67e-04	189	65	4	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 HYDIN	1.67e-04	189	65	4	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NHS SDK1 HYDIN MAP3K1	1.67e-04	189	65	4	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 FAM110D ACTN4 ACTN1	1.67e-04	189	65	4	476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 FAM110D ACTN4 ACTN1	1.67e-04	189	65	4	3fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NHS SDK1 HYDIN MAP3K1	1.67e-04	189	65	4	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 HYDIN MAP3K1 LYG1	1.67e-04	189	65	4	bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FLI1 NHS ADCY3 PDZD2	1.71e-04	190	65	4	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	GALNT14 NHS SDK1 ADCY2	1.71e-04	190	65	4	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	Frontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NXF2 SLC34A3 SEC14L5	1.73e-04	74	65	3	a53f2e1f1044f3745a1eff5ba6275c8f1fbf3ae0
ToppCell	Frontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NXF2 SLC34A3 SEC14L5	1.73e-04	74	65	3	ae547cb8bbd780b19d9c6b555c27dad932dcc753
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 PDZD2	1.74e-04	191	65	4	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 PDZD2	1.74e-04	191	65	4	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	FLI1 PTPRF ACTN1 ITGB4	1.78e-04	192	65	4	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRF HSD11B2 SLC14A2 SDK1	1.78e-04	192	65	4	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 FAM110D ACTN1 ITGB4	1.78e-04	192	65	4	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP1 PTPRF UBR4 HYDIN	1.78e-04	192	65	4	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	facs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP1 GALNT14 ACTN1 MAP3K1	1.81e-04	193	65	4	eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CERKL PTPRF SDK1 HYDIN	1.81e-04	193	65	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PTPRF UBR4 PC	1.81e-04	193	65	4	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PTPRF UBR4 PC	1.81e-04	193	65	4	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 FAM110D ACTN1 ITGB4	1.81e-04	193	65	4	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSD11B2 SLC14A2 ITGB4 SDK1	1.85e-04	194	65	4	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 FAM110D ACTN4 ITGB4	1.85e-04	194	65	4	e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 FAM110D ACTN4 ITGB4	1.85e-04	194	65	4	4b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	NYNRIN NHS ITGB4 ADCY3	1.88e-04	195	65	4	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC34A3 ITGB4 SEC14L5	1.95e-04	77	65	3	4d6e2486dd7702c4e0115567dd0a2c16617816aa
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC34A3 ITGB4 SEC14L5	1.95e-04	77	65	3	ddd54a5ef6a1fc8be1e852c2192204a749b819c1
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NHS ACTN1 SDK1 ADCY3	1.96e-04	197	65	4	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRF ACTN4 ACTN1 ITGB4	1.96e-04	197	65	4	f4dad4423384a2a25e064c849ffccf2811573be0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 NHS SDK1 HYDIN	1.96e-04	197	65	4	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLI1 FAM110D ACTN1 ITGB4	1.96e-04	197	65	4	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	Parenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IBA57 ZNF324B ADCY2 ADCY3	2.04e-04	199	65	4	6f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCell	Parenchymal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IBA57 ZNF324B ADCY2 ADCY3	2.04e-04	199	65	4	1aa99d21bf61b86df4a966dc47634044430aa39f
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLI1 FAM110D ACTN1 ITGB4	2.04e-04	199	65	4	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLI1 FAM110D ACTN1 ITGB4	2.08e-04	200	65	4	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GALNT14 NHS SDK1 ADCY2	2.08e-04	200	65	4	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CERKL SLC14A2 ADCY2 HYDIN	2.08e-04	200	65	4	4992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CERKL HYDIN SEC14L5 PDZD2	2.08e-04	200	65	4	0f23e72649a274043bf23e0952a9b5707c516acf
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GALNT14 NHS ITGB4 SDK1	2.08e-04	200	65	4	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC34A3 ITGB4 SEC14L5	2.35e-04	82	65	3	8d4b3339d34ee23060c85fb4e2e42bfe9579c738
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC34A3 ITGB4 SEC14L5	2.35e-04	82	65	3	0c07ac1e7eb64bca6b09979e204d4b86338b0e40
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN4 ACTN1	4.33e-05	5	62	2	DOID:0111128 (implicated_via_orthology)
Disease	response to antineoplastic agent	GALNT14 UBR4 SH2D4B ADCY2	5.73e-05	99	62	4	GO_0097327
Disease	Congenital Hydrocephalus	WDR81 HYDIN	1.21e-04	8	62	2	C0020256
Disease	anxiety disorder, stress-related disorder	SDK1 ADCY2	2.83e-04	12	62	2	EFO_0006788, EFO_0010098
Disease	smoking behavior	PTPRF ACTN1 SLC14A2 SDK1 BRWD1	7.55e-04	341	62	5	EFO_0004318
Disease	neoplasm of mature B-cells	FLI1 SLC14A2	8.05e-04	20	62	2	EFO_0000096
Disease	Attention Deficit Disorder	STS CHRNA4	9.77e-04	22	62	2	C0041671
Disease	Minimal Brain Dysfunction	STS CHRNA4	9.77e-04	22	62	2	C1321905
Disease	Attention deficit hyperactivity disorder	STS CHRNA4	1.16e-03	24	62	2	C1263846
Disease	smoking behaviour measurement	PTPRF SDK1 CHRNA4 PRSS36	1.24e-03	222	62	4	EFO_0005671
Disease	C-C motif chemokine 7 measurement	ELP3 CDH4	1.70e-03	29	62	2	EFO_0008054
Disease	Severe Congenital Microcephaly	TSEN34 DYNC1H1	1.94e-03	31	62	2	C3853041
Disease	immature platelet measurement	ACTN1 ZNF324B SEC14L5	2.03e-03	119	62	3	EFO_0803541
Disease	microcephaly (implicated_via_orthology)	ASPM WDR81	2.07e-03	32	62	2	DOID:10907 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
IRIPSELIWRPDIVL	CHRNA4	111	P43681
PTWVRRVFLDIVPRL	CHRNA4	341	P43681
RRTIPWLENRVPENT	ACTN1	291	P12814
TVPVWRRQPVRVLSL	DNMT3L	181	Q9UJW3
RTIPWLEDRVPQKTI	ACTN4	311	O43707
RRKVTVEPHPELRVW	IBA57	146	Q5T440
LEPVTAWEVQVPRVR	HSD11B1L	286	Q7Z5J1
WIALSRLARPQRLPV	HSD11B2	66	P80365
PVRTRIVSRLKPDWV	ASPM	3436	Q8IZT6
RLPRLEEIRIWGPLQ	ADAMTS13	636	Q76LX8
LILSVDPWRIRQILI	INTS8	516	Q75QN2
VTVLQRRRPAWLPVR	SLC34A3	531	Q8N130
QVESPWRLIRPSVIS	PDZD2	571	O15018
VSAPTIPVRRRLAWD	MDM1	431	Q8TC05
RRVTWRLPPELIPRL	ITGB4	1386	P16144
RRLVLPVFGVLWITV	GALNT14	6	Q96FL9
WRVLLPSRPRAERVA	PRSS36	381	Q5K4E3
IIANRPWPRISLTII	ADCY2	671	Q08462
VRRVPSWIAPNLITI	CEPT1	76	Q9Y6K0
VLLRNVTLLPVAWRI	HYDIN	2956	Q4G0P3
ERRVIVPADPTLWTQ	FLI1	121	Q01543
PRTWDLRQLQVRERP	IFNL2	81	Q8IZJ0
RRKRDWVIPPINVPE	CDH4	166	P55283
PDRVTRRVLPYVLWL	ADCY3	131	O60266
VVLSERALRWRPIQP	CERKL	61	Q49MI3
AWKRRVVVPEVPLGI	BRWD1	736	Q9NSI6
DLWRGLPRVRPTIDI	C1QTNF8	51	P60827
RILALVPPWTRVYRV	ELP3	351	Q9H9T3
PILSTWIRVTVRIPV	FCRL3	366	Q96P31
WIRVTVRIPVSHPVL	FCRL3	371	Q96P31
TRIKEIQRRFPTWTP	LYG1	136	Q8N1E2
DLPVRVLPRRVWRDC	HUS1B	131	Q8NHY5
RPLETLPVEGLIRIW	DYNC1H1	2811	Q14204
RVPPVIVLENQGLRW	EMC9	126	Q9Y3B6
TIRWTIPPETLRKRN	CCDC168	7031	Q8NDH2
AAVVIPPTWILRARR	DGKZ	236	Q13574
IVRAPRVFPVLWTLI	SEC14L5	421	O43304
FPEVRLTSVRIVWQP	SDK1	1386	Q7Z5N4
TPVRKVTPAWVRQVL	SACS	621	Q9NZJ4
SRVRRAWVIPPISVS	CDH15	41	P55291
TRIQLSWLLPPQERI	PTPRF	526	P10586
PRVWVVPTQLRRDLI	NYNRIN	1531	Q9P2P1
EIRITTWRNRKPPER	NXF2	96	Q9GZY0
WLERRNRRGPVVVKP	MAP3K1	201	Q13233
IVSVWSPRRLRNDPV	TAS2R50	246	P59544
PRVLRPTLVISQWTE	RGL2	521	O15211
VPREVRPITWRLLSG	TBC1D22B	211	Q9NU19
PLRRVAVWPVLRERA	SPATA5L1	106	Q9BVQ7
VKGWRVPILPDRRSV	TMEM132E	551	Q6IEE7
RIVEPQWLCRQRRPA	NHS	6	Q6T4R5
DPLVGRRLVVIWVLV	SGPP1	156	Q9BX95
IRVPGILRWPRVIQA	STS	376	P08842
VALLPVWVVLARRSP	SLC41A1	296	Q8IVJ1
PPVSVVERNARVIQW	FAM110D	241	Q8TAY7
LSVLLARIPQRAPRW	ABHD10	31	Q9NUJ1
PLLSRVQAALVWERP	RETREG3	51	Q86VR2
RPRVVIQLERGEEPW	ZNF324	46	O75467
RPRPVKARPLDWRVQ	TSEN34	191	Q9BSV6
PPIWAIQVQLRSRRL	ZNRF4	381	Q8WWF5
RWVRQPVQVPVTLVR	RBPJ	416	Q06330
LALPVRTWERPLRPV	SH2D4B	281	Q5SQS7
RTWERPLRPVSRDVI	SH2D4B	286	Q5SQS7
PLRPVSRDVIVRWFK	SH2D4B	291	Q5SQS7
PVFVVRWTPEGRRLV	WDR33	121	Q9C0J8
LPPEQWRATRVEILR	UBR4	5046	Q5T4S7
WSEVQVPLLLRAIPV	SLC14A2	736	Q15849
ECPWRRLQELRELIP	PC	621	P11498
RVRTLQPDAPLWVRF	WDR81	786	Q562E7
EPVRVVWRLQRPLAE	TYSND1	546	Q2T9J0
RPRVVIQLERGEEPW	ZNF324B	46	Q6AW86