Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcell cortex

FGB DST MACF1

8.23e-04371113GO:0005938
DomainGAR

DST MACF1

4.72e-066112PS51460
DomainGAS_dom

DST MACF1

4.72e-066112IPR003108
Domain-

DST MACF1

4.72e-0661123.30.920.20
Domain-

DST MACF1

4.72e-0661123.90.1290.10
DomainGAS2

DST MACF1

4.72e-066112PF02187
DomainGAS2

DST MACF1

4.72e-066112SM00243
DomainPlectin_repeat

DST MACF1

6.61e-067112IPR001101
DomainPlectin

DST MACF1

6.61e-067112PF00681
DomainPLEC

DST MACF1

6.61e-067112SM00250
DomainACTININ_2

DST MACF1

7.92e-0523112PS00020
DomainActinin_actin-bd_CS

DST MACF1

7.92e-0523112IPR001589
DomainACTININ_1

DST MACF1

7.92e-0523112PS00019
DomainSpectrin

DST MACF1

7.92e-0523112PF00435
DomainSpectrin_repeat

DST MACF1

1.27e-0429112IPR002017
DomainSpectrin/alpha-actinin

DST MACF1

1.55e-0432112IPR018159
DomainSPEC

DST MACF1

1.55e-0432112SM00150
DomainCH

DST MACF1

6.43e-0465112SM00033
DomainCH

DST MACF1

7.45e-0470112PF00307
Domain-

DST MACF1

7.66e-04711121.10.418.10
DomainCH

DST MACF1

8.10e-0473112PS50021
DomainCH-domain

DST MACF1

8.55e-0475112IPR001715
DomainEF-hand_7

DST MACF1

1.10e-0385112PF13499
DomainEF-hand_1

DST MACF1

3.45e-03152112PF00036
DomainEFh

DST MACF1

3.72e-03158112SM00054
DomainEF_Hand_1_Ca_BS

DST MACF1

4.54e-03175112IPR018247
DomainEF_HAND_1

DST MACF1

6.12e-03204112PS00018
DomainSH3

DST MACF1

6.84e-03216112PS50002
DomainSH3_domain

DST MACF1

7.08e-03220112IPR001452
DomainEF_HAND_2

DST MACF1

7.78e-03231112PS50222
DomainEF_hand_dom

DST MACF1

7.85e-03232112IPR002048
Domain-

DST MACF1

9.85e-032611121.10.238.10
DomainEF-hand-dom_pair

DST MACF1

1.18e-02287112IPR011992
DomainKinase-like_dom

DST MACF1

3.89e-02542112IPR011009
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

9.09e-08211211002341
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

2.73e-07311212399109
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1

5.45e-0741128954775
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

TOP2A TNRC18 DST MACF1

2.55e-0633211437433992
Pubmed

The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.

DST MACF1

4.99e-061111216815997
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

DST MACF1

1.72e-052011221689717
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

TOP2A DST MACF1

4.77e-0523411336243803
Pubmed

Interaction network of human early embryonic transcription factors.

TOP2A TNRC18 DNTTIP1

1.58e-0435111338297188
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

TOP2A TNRC18

1.81e-046411222865885
InteractionMEX3A interactions

TOP2A TNRC18 DST MACF1

3.85e-05384114int:MEX3A
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

3.59e-06872939
GeneFamilyEF-hand domain containing

DST MACF1

2.95e-0321972863
CoexpressionJAK2_DN.V1_DN

TNRC18 MGAT5 MACF1

2.76e-05147113M2872
CoexpressionTRAVAGLINI_LUNG_ALVEOLAR_FIBROBLAST_CELL

CHRDL1 DST MACF1

3.82e-05164113M41676
CoexpressionGSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

TOP2A CREG2 AFG1L

6.80e-05199113M7967
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

MGAT5 DST MACF1

8.21e-05212113M39221
CoexpressionDAUER_STAT3_TARGETS_UP

FEM1C FGB

1.79e-0448112M12391
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

9.33e-061751131799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.29e-051951134243190ad291d56694e2155954dbaa879c9d3844
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.29e-05195113df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.31e-0519611342e9828222a9663525d571633e8a454c30bfa7f8
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.31e-05196113cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.31e-051961139737a5f006d37b549f281e1863aca558e1e4dc99
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 DST MACF1

1.31e-051961137d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.33e-0519711394a9603cbd3516fbcce871909693b88f20d41713
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST MACF1

1.33e-0519711313896ec65ccda0b928c91d41112dc01b480036b7
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

CHRDL1 DST MACF1

1.33e-051971136c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 DST MACF1

1.35e-05198113f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.37e-051991137f4840ae6a888380feca722543e5e52783f3e35d
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.37e-05199113fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.37e-051991139a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

CHRDL1 DST MACF1

1.37e-05199113f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.37e-05199113301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCelldistal-mesenchymal-Alveolar_Fibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.37e-05199113655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

CHRDL1 DST MACF1

1.37e-051991139c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

TOP2A DST MACF1

1.37e-051991137ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CHRDL1 DST MACF1

1.37e-05199113b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 DST MACF1

1.37e-0519911366a79732caf2f04c09b4d9832377aa01ca477677
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CHRDL1 DST MACF1

1.39e-05200113aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 DST MACF1

1.39e-052001138978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.39e-052001135c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.39e-05200113c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCellmedial-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.39e-05200113cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHRDL1 DST MACF1

1.39e-05200113a510deaada669e690329183e18df02870bd204b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHRDL1 DST MACF1

1.39e-05200113dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCelldistal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 DST MACF1

1.39e-0520011320112be28f80baffad92641c9cfd7c3718967dbb
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

TOP2A MACF1

4.83e-04135112ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DST MACF1

4.83e-04135112b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CREG2 CHRDL1

4.97e-041371128e2fa2ef8becace96a68bb85c002329110902fbb
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-dnT|Multiple_Sclerosis / Disease, Lineage and Cell Type

TOP2A AFG1L

5.57e-04145112d24894be1d6664df9a6af8ea33f2ffce0c718635
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOP2A CREG2

5.80e-041481125983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A CREG2

6.03e-04151112f3406094ce79cc80398b82d58ca6fd87a96e68d4
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A CREG2

6.03e-04151112523dcd243c285a6b74830a93c82cca8784edd658
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

CREG2 CHRDL1

6.27e-04154112dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

CREG2 CHRDL1

6.27e-041541124bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CREG2 CHRDL1

6.44e-0415611296747447ba7dc2c10079cee44394b19ce60b2f41
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A FEM1C

6.44e-041561128349604bd801e20d33770f7d8243598c3756302b
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MGAT5 MACF1

6.68e-041591122881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DST MACF1

6.77e-041601120293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DST MACF1

6.77e-041601123eaae86fa08f7651021316f8e5811bf48055591e
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

DST AFG1L

6.85e-041611129fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

FEM1C DST

7.02e-04163112d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

TOP2A AFG1L

7.37e-04167112315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 MGAT5

7.46e-041681122781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCellControl-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

MGAT5 DST

7.46e-04168112d7118d39253ed9790908b850088ebfc5a86f4065
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

7.46e-04168112e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MGAT5 MACF1

7.54e-04169112c3a6179a64589a370108fea809b157839347759c
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CHRDL1 DST

7.63e-041701126c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TOP2A AFG1L

7.72e-041711124ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 MGAT5

7.72e-0417111270963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 MGAT5

7.81e-0417211284d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1

7.90e-041731120672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1

7.90e-04173112869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1

7.90e-04173112870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

TOP2A CHRDL1

7.99e-04174112029394e107bf7ad58056d2216070aa2e964fff12
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1

8.09e-041751121ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 DST

8.09e-04175112334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 DST

8.09e-04175112da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP|lymph-node_spleen / Manually curated celltypes from each tissue

TOP2A CHRDL1

8.18e-04176112de67ed15a50d2515ba6d152c1011a3367f77aedd
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TOP2A CHRDL1

8.18e-041761126b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A MGAT5

8.18e-04176112a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOP2A CREG2

8.27e-0417711267cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCellfacs-Brain_Myeloid-Striatum|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB MACF1

8.27e-04177112efb1990fd1d216f64261e81017299783afb24a1e
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB DST

8.36e-041781125cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB DST

8.36e-04178112f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FEM1C MACF1

8.36e-04178112c87945146b2734141f07b39d268e0d8086ee0364
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DST MACF1

8.36e-04178112ad3de3e03a401dac64431a541899445262246347
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|368C / Donor, Lineage, Cell class and subclass (all cells)

TOP2A AFG1L

8.46e-04179112ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

8.46e-041791127394e77e665bf16d3733df91bb12907be460ab44
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 DST

8.55e-04180112af2bafcd1b2082629de3ea336711add01565c4c4
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 DST

8.55e-04180112f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellfacs-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB MACF1

8.55e-04180112c0c3144011856d005aebd5cdc79f89fee32083a8
ToppCellfacs-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGB MACF1

8.55e-0418011287fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 DST

8.64e-041811122b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST

8.64e-04181112b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 DST

8.64e-041811126aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 DST

8.64e-0418111240d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

8.64e-041811125bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

TOP2A FGB

8.64e-04181112be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DST MACF1

8.64e-04181112beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

8.64e-041811128e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 DST

8.64e-0418111240df0afcb6848202da54670e84f22d7c3a515d01
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST

8.74e-0418211253c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TOP2A FGB

8.83e-041831120d21befacefc6c597e7b501ed41b7fe9385a78df
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 DST

8.83e-041831124d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TOP2A AFG1L

8.83e-04183112f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

TOP2A MGAT5

8.93e-04184112c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

TOP2A MGAT5

8.93e-041841122fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

FEM1C DST

8.93e-041841127fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DST MACF1

8.93e-04184112d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP2A MGAT5

9.03e-04185112969248b63d4ce335f223528de756bcddffadbd77
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CHRDL1 DST

9.03e-041851121ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

9.03e-041851129197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

TOP2A DST

9.03e-041851129d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

TOP2A CREG2

9.03e-041851120ae9c646679c69a553eda670aef0e0495feb0286
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

9.03e-04185112b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 DST

9.03e-04185112ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST MACF1

2.02e-044952GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_3
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST MACF1

2.10e-045052GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST MACF1

2.10e-045052GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drugdicentrine

FGB CHRDL1

1.16e-0511112CID000101300
Drugbeta-propiolactone

FGB DST

1.04e-0432112CID000002365
DrugAC1LAKND

CHRDL1 DST

3.95e-0462112CID000470146
Drugrebamipide

TOP2A FGB

5.78e-0475112ctd:C052785
DrugAC1NMZ1B

FGB DST

5.78e-0475112CID005034185
DrugN-acetyl-4-benzoquinoneimine

TOP2A DNTTIP1

6.09e-0477112ctd:C028473
Drugplakin

DST MACF1

6.90e-0482112CID000018752
Drugticlopidine

FGB DST

1.09e-03103112CID000005472
Drugmonodansylcadaverine

FGB MGAT5

1.26e-03111112CID000004247
DrugPPACK

FGB DST

1.30e-03113112CID003036757
Diseasecancer (implicated_via_orthology)

TOP2A DST MACF1

1.16e-04268113DOID:162 (implicated_via_orthology)
DiseaseIGF-1 measurement

TOP2A FGB AFG1L

6.72e-04488113EFO_0004627
Diseaseopen-angle glaucoma

MGAT5 DST

2.21e-03191112EFO_0004190
Diseasegout

MGAT5 DST

2.32e-03196112EFO_0004274
Diseaseoptic disc size measurement

MGAT5 MACF1

2.54e-03205112EFO_0004832
Diseasecleft lip

MGAT5 DST

4.79e-03284112EFO_0003959
DiseaseMalignant neoplasm of breast

TOP2A FEM1C MACF1

6.37e-031074113C0006142
DiseaseFEV/FEC ratio

MGAT5 CHRDL1 DST

9.23e-031228113EFO_0004713
Diseasetestosterone measurement

MGAT5 CHRDL1 MACF1

1.02e-021275113EFO_0004908
Diseasefatty acid measurement

MGAT5 MACF1

1.10e-02436112EFO_0005110

Protein segments in the cluster

PeptideGeneStartEntry
MDMFYAYVEMKRKKR

AFG1L

146

Q8WV93
MRKWPRQYEWFFMKM

CREG2

246

Q8IUH2
LKYWKKAMNMRYSDR

FEM1C

266

Q96JP0
YSMMKKHEEFRWMRL

MGAT5

226

Q09328
YMRWMNHKKSRVMDF

DST

7191

Q03001
KGSWYSMRKMSMKIR

FGB

471

P02675
KYMRWMNHKKSRVMD

MACF1

3161

O94854
MRKKWKMGGMKYIFS

CHRDL1

1

Q9BU40
YSWMRKKEERMYAMK

TNRC18

1456

O15417
SWMVEKMRKYMETLR

DNTTIP1

301

Q9H147
YKKMFKQTWMDNMGR

TOP2A

186

P11388