Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponent9+2 motile cilium

RSPH10B2 RSPH10B CFAP221 CFAP65

1.50e-05238144GO:0097729
GeneOntologyCellularComponentmotile cilium

RSPH10B2 RSPH10B CFAP221 CFAP65

7.15e-05355144GO:0031514
MousePhenodecreased total fat pad weight

FOXP2 RBL1

7.83e-0519102MP:0008907
DomainFOXP-CC

FOXP2 FOXP4

2.68e-064132IPR032354
DomainFOXP-CC

FOXP2 FOXP4

2.68e-064132PF16159
DomainPapD-like

CFAP221 CFAP65

1.61e-059132IPR008962
DomainTF_fork_head_CS_2

FOXP2 FOXP4

4.55e-0446132IPR030456
DomainTF_fork_head_CS_1

FOXP2 FOXP4

4.75e-0447132IPR018122
DomainFORK_HEAD_3

FOXP2 FOXP4

5.16e-0449132PS50039
DomainFH

FOXP2 FOXP4

5.16e-0449132SM00339
DomainFORK_HEAD_1

FOXP2 FOXP4

5.16e-0449132PS00657
DomainFORK_HEAD_2

FOXP2 FOXP4

5.16e-0449132PS00658
DomainForkhead

FOXP2 FOXP4

5.16e-0449132PF00250
DomainFork_head_dom

FOXP2 FOXP4

5.16e-0449132IPR001766
Domain-

FOXP2 FOXP4

9.72e-032181321.10.10.10
DomainWHTH_DNA-bd_dom

FOXP2 FOXP4

1.19e-02242132IPR011991
DomainZINC_FINGER_C2H2_2

CBLL1 FOXP2 FOXP4

1.49e-02775133PS50157
DomainZINC_FINGER_C2H2_1

CBLL1 FOXP2 FOXP4

1.50e-02777133PS00028
DomainZnf_C2H2-like

CBLL1 FOXP2 FOXP4

1.60e-02796133IPR015880
DomainZnF_C2H2

CBLL1 FOXP2 FOXP4

1.67e-02808133SM00355
Pubmed

Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues.

FOXP2 FOXP4

4.51e-07314214516685
Pubmed

Human-specific transcriptional regulation of CNS development genes by FOXP2.

FOXP2 FOXP4

4.51e-07314219907493
Pubmed

Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.

FOXP2 FOXP4

4.51e-07314225027557
Pubmed

Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System.

FOXP2 FOXP4

4.51e-07314228507505
Pubmed

Exome sequencing supports a de novo mutational paradigm for schizophrenia.

CELF2 MTOR CFAP65

5.08e-074014321822266
Pubmed

Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

FOXP2 FOXP4

9.02e-07414214701752
Pubmed

Identification and characterization of T reg-like cells in zebrafish.

FOXP2 FOXP4

9.02e-07414229066577
Pubmed

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

FOXP2 FOXP4

2.25e-06614228591638
Pubmed

Generation of mice with a conditional Foxp2 null allele.

FOXP2 FOXP4

2.25e-06614217619227
Pubmed

Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6.

FOXP2 FOXP4

3.16e-06714220185820
Pubmed

Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.

FOXP2 FOXP4

6.76e-061014228384713
Pubmed

Foxp1/2/4 regulate endochondral ossification as a suppresser complex.

FOXP2 FOXP4

8.26e-061114225527076
Pubmed

Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases.

FOXP2 MTOR

9.91e-061214224857653
Pubmed

Tat predominantly associates with host promoter elements in HIV-1-infected T-cells - regulatory basis of transcriptional repression of c-Rel.

FOXP2 FOXP4

1.58e-051514225472883
Pubmed

The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.

FOXP2 FOXP4

1.80e-051614226021489
Pubmed

Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.

FOXP2 FOXP4

1.80e-051614222542185
Pubmed

Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates.

FOXP2 FOXP4

3.46e-052214232049024
Pubmed

Cerebellar cortical lamination and foliation require cyclin A2.

FOXP2 FOXP4

3.79e-052314224184637
Pubmed

Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.

FOXP2 FOXP4

4.49e-052514217428829
Pubmed

Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development.

FOXP2 FOXP4

4.86e-052614227341756
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

FOXP2 FOXP4

5.65e-052814229365100
Pubmed

Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.

FOXP2 FOXP4

7.89e-053314218662545
Pubmed

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.

FOXP2 CELF2

8.89e-053514237758766
Pubmed

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.

FOXP2 MTOR

8.89e-053514235858542
Pubmed

Epithelial inactivation of Yy1 abrogates lung branching morphogenesis.

FOXP2 FOXP4

1.35e-044314226329601
Pubmed

Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer.

RRP1B MTOR

2.90e-046314234718347
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

FOXP2 RRP1B MTOR

3.62e-0435814332460013
Pubmed

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.

FOXP2 MTOR

3.68e-047114229346117
InteractionBNC2 interactions

FOXP2 FOXP4

3.48e-0513142int:BNC2
InteractionTOX interactions

FOXP2 FOXP4

4.06e-0514142int:TOX
InteractionTFDP1 interactions

FOXP2 RBL1 FOXP4

9.70e-05133143int:TFDP1
Cytoband7p22.1

RSPH10B2 RSPH10B

9.26e-05471427p22.1
CytobandEnsembl 112 genes in cytogenetic band chr7p22

RSPH10B2 RSPH10B

7.52e-04134142chr7p22
GeneFamilyForkhead boxes

FOXP2 FOXP4

1.53e-044382508
CoexpressionDESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS

RSPH10B2 RSPH10B CFAP221 CFAP65

1.91e-05317144M40298
CoexpressionGSE360_DC_VS_MAC_T_GONDII_UP

CELF2 RRP1B TNK1

1.45e-04198143M5183
CoexpressionGSE31082_DP_VS_CD8_SP_THYMOCYTE_DN

FOXP2 RRP1B SLC26A11

1.50e-04200143M5068
CoexpressionGSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN

RRP1B MTOR RBL1

1.50e-04200143M9672
CoexpressionDESCARTES_FETAL_LUNG_CILIATED_EPITHELIAL_CELLS

RSPH10B2 RSPH10B CFAP221 CFAP65

1.51e-04540144M40241
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_UP

MTOR FOXP4

1.75e-0437142M1367
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_UP

MTOR FOXP4

1.84e-0438142MM782
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_UP

MTOR FOXP4

3.20e-0450142M847
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_UP

MTOR FOXP4

3.20e-0450142MM789
CoexpressionDESCARTES_MAIN_FETAL_CILIATED_EPITHELIAL_CELLS

RSPH10B2 RSPH10B CFAP221 CFAP65

3.61e-04678144M40124
CoexpressionDESCARTES_ORGANOGENESIS_EPENDYMAL_CELL

RSPH10B CFAP221 CFAP65

4.11e-04282143MM3642
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 RSPH10B CFAP221 CFAP65

3.52e-07198144f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

RSPH10B2 RSPH10B CFAP221 CFAP65

3.66e-072001443305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 RSPH10B CFAP221 CFAP65

3.66e-0720014473ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

RSPH10B CFAP221 CFAP65

1.45e-0515614310d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXP2 CELF2 FOXP4

2.45e-051861434e94158db52df41d71e67b02b9895a358eebee0f
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

FOXP2 CFAP221 CFAP65

2.69e-05192143354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CELF2 CFAP221

2.69e-051921435c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RSPH10B2 CFAP221 CFAP65

2.73e-05193143ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RSPH10B CFAP221 CFAP65

2.73e-05193143e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RSPH10B CFAP221 CFAP65

2.77e-05194143756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

RSPH10B CFAP221 CFAP65

2.82e-0519514360067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

RSPH10B CFAP221 CFAP65

2.95e-051981436d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 CFAP221 CFAP65

3.04e-05200143af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RSPH10B CFAP221 CFAP65

3.04e-052001434992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 CFAP221 CFAP65

3.04e-05200143e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RSPH10B2 CFAP221 CFAP65

3.04e-0520014331d75c26055177d656df1fbb10b764cebd61e122
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

CFAP221 CFAP65

4.82e-04105142339e53aaa2b5255f248e0993268f6acd63762084
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTOR FOXP4

5.58e-0411314291e73e3b93be242fef0f14eddd8085a1f1c730ef
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTOR FOXP4

5.58e-04113142357bc20edc5bc14eab8262d52260ed1686e9dc54
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RRP1B TNK1

6.18e-04119142abb7eb746073f3be44a8fab8456b756c1d52b5a3
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXP2 FOXP4

7.37e-041301426434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTOR FOXP4

7.60e-041321424152529611eeacf0c547e2a134d5b98c45426b13
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CELF2 RSPH10B

7.60e-041321427d6cd16ca1d83d9a618ef5b7fb300c1509eeb129
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CELF2 SLC26A11

7.94e-04135142b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

8.30e-04138142a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

RSPH10B2 CFAP221

8.78e-04142142369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

8.90e-041431427a7a9829ba63468c9745904d9e993590051207ab
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

9.53e-04148142d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

9.53e-04148142c8e93b87212f55774223caa385859c566fa1981f
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

9.92e-041511429cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

9.92e-0415114216fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

9.92e-0415114281cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CELF2 CFAP221

1.02e-031531428bc09b8b1a32a8d7ac8201c626d2b306e7cc2972
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

1.03e-031541424e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

1.03e-031541427556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

1.03e-0315414258072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP221 CFAP65

1.03e-031541429ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.08e-031581421cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.11e-0316014203b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCellSevere-Lymphoid-NK-Proliferating_T|Severe / Condition, Lineage, Cell class and cell subclass

RBL1 CFAP65

1.11e-03160142cb2276d9bd78508644420e9580d3c17b914224cb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.17e-031641421cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-Activated_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELF2 RBL1

1.17e-0316414224fdea5113d92b96f56b06dd2449910a3c785e69
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TNK1 RSPH10B

1.18e-03165142ebd668e87e5961a124d1d6fc25d1f03e4af05cd4
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

CBLL1 CFAP221

1.22e-03168142c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPH10B CFAP65

1.22e-03168142fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A11 TNK1

1.22e-031681422e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPH10B CFAP65

1.22e-031681427edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CFAP221

1.24e-03169142319cba07263bf41fcbcbfecd117f91b729394241
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RSPH10B CFAP221

1.24e-03169142fba841664939c771881ba97f14ef1df6635c04ff
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

RSPH10B2 CFAP65

1.24e-03169142425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

FOXP2 CELF2

1.24e-031691426373562ab3b1765060212a6a53d6543e7e942e80
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP221 CFAP65

1.24e-0316914214aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CFAP221

1.25e-031701425de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RSPH10B CFAP221

1.27e-0317114252aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.28e-031721420c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBL1 CFAP65

1.28e-03172142eba1568d4307e91c94fc616549057cbed8df5840
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

RSPH10B2 CFAP65

1.28e-031721426b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.28e-03172142eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP221 CFAP65

1.30e-03173142a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CFAP221

1.30e-031731429a2d42f8d9cb834856522661d524abb91c4637c5
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

RSPH10B CFAP221

1.31e-03174142f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCelldroplet-Lung-nan-21m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.33e-031751423ed22ea41810e73c02db4f2d03745e4ce7e43bb1
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RSPH10B2 CFAP65

1.33e-03175142c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP4 RSPH10B

1.33e-031751429a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

RSPH10B CFAP221

1.33e-03175142c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP4 RSPH10B

1.33e-031751422b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCelldroplet-Lung-nan-21m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.33e-031751428fb1e5f6aa68274adf322401db8c7b80e8c554d7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.33e-03175142e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RSPH10B2 CFAP65

1.33e-03175142b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP4 RSPH10B

1.33e-0317514254c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP221 CFAP65

1.34e-03176142dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.34e-03176142ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TNK1 RSPH10B2

1.34e-03176142bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXP2 SLC26A11

1.34e-03176142a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.36e-03177142bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TNK1 RSPH10B2

1.36e-031771423d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.36e-03177142ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.36e-03177142e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP221 CFAP65

1.36e-03177142d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP221 CFAP65

1.36e-03177142d5640f0097878f0dac671e51dc51310278bb2682
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

RSPH10B2 CFAP221

1.37e-03178142d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.37e-03178142579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.37e-031781424df6218b20c2f076c22346d23260964cc0d73e65
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CFAP221

1.37e-03178142f7f88879a05b2b5fa92cf5317b76f7a3064d1358
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.37e-03178142b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP221 CFAP65

1.39e-031791425e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP221 CFAP65

1.39e-03179142d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP221 CFAP65

1.39e-031791428a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

FOXP2 CELF2

1.39e-03179142dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

FOXP2 CFAP221

1.40e-03180142198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

RSPH10B CFAP65

1.40e-0318014285fc9b164147b28545e2397d32302eea03ef6346
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CFAP221

1.40e-031801422ae39e26a8e7d5d4d3e1e71609a8ec36fd9855aa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.42e-031811429d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RSPH10B2 CFAP65

1.42e-031811425a4574f1bfd0b4ca78da7effda43420857e17296
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 CFAP221

1.42e-031811426a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXP2 CFAP221

1.42e-031811426e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 CFAP65

1.42e-0318114211cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

RSPH10B2 CFAP65

1.42e-03181142a4e891603645f694687e68e585744ddc1a3c8697
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RSPH10B2 CFAP65

1.42e-03181142dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Ciliated|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RSPH10B CFAP65

1.42e-031811428eed9d46d924b16f6dd1a025ff612244b02b4391
DrugAC1L1ABQ

FOXP2 MTOR

8.82e-0523142CID000000920
DrugLabetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A

RRP1B TNK1 RBL1

2.13e-041961433167_DN
DrugAzaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

RRP1B TNK1 MTOR

2.16e-041971437231_DN
DrugEthopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; HL60; HT_HG-U133A

CBLL1 RRP1B RBL1

2.20e-041981433038_DN
DrugGuanethidine sulfate [60-02-6]; Down 200; 13.4uM; PC3; HT_HG-U133A

CELF2 TNK1 RBL1

2.20e-041981435731_DN
DrugTolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; MCF7; HT_HG-U133A

RRP1B TNK1 RBL1

2.23e-041991431500_DN
DrugAzacyclonol [115-46-8]; Down 200; 15uM; PC3; HT_HG-U133A

RRP1B MTOR RBL1

2.26e-042001436298_DN
DrugMolPort-016-580-972

FOXP2 MTOR

4.40e-0451142CID009938589
Drughonokiol

MTOR RBL1

5.69e-0458142CID000072303
Diseasespecific developmental disorder (implicated_via_orthology)

FOXP2 FOXP4

1.07e-064132DOID:0060038 (implicated_via_orthology)
Diseaseautism spectrum disorder (is_implicated_in)

MBD5 FOXP2

2.14e-0516132DOID:0060041 (is_implicated_in)
DiseaseSchizophrenia

FOXP2 CELF2 MTOR CFAP65

4.59e-04883134C0036341
Diseasecongestive heart failure (is_marker_for)

MTOR FOXP4

5.83e-0482132DOID:6000 (is_marker_for)
Diseaseurinary albumin to creatinine ratio

FOXP2 CELF2

2.73e-03179132EFO_0007778
DiseaseMajor Depressive Disorder

FOXP2 MTOR

4.96e-03243132C1269683
DiseaseUnipolar Depression

FOXP2 MTOR

5.62e-03259132C0041696
Diseasecancer (implicated_via_orthology)

MTOR RBL1

6.00e-03268132DOID:162 (implicated_via_orthology)
Diseaseneuroticism measurement

MBD5 FOXP2 CELF2

6.61e-03909133EFO_0007660

Protein segments in the cluster

PeptideGeneStartEntry
IKTLPGMHHPIQMKP

CELF2

106

O95319
PSAAPPHEPTMKMRH

RSPH10B

566

P0C881
PSAAPPHEPTMKMRH

RSPH10B2

566

B2RC85
PPLKSMAMRLHFQPP

CFAP65

706

Q6ZU64
MTHLHMRPSEPKPSP

FOXP2

406

O15409
MMAHLHMRPSEPKPF

FOXP4

366

Q8IVH2
IMPPDKHHMSHIPPK

CBLL1

221

Q75N03
MEIPRAMFHHKPPQG

MBD5

321

Q9P267
VLMHKPLRHPGMPKG

MTOR

546

P42345
PPEKAMMHINFHRPP

CFAP221

281

Q4G0U5
MMHINFHRPPAKPKP

CFAP221

286

Q4G0U5
EHPPAVPMHNKRKRP

RRP1B

461

Q14684
HMMDAPPLSPFPHIK

RBL1

956

P28749
KLMRDHVPPVHPEMP

SLC26A11

216

Q86WA9
KRKPPHNHPMGMPGA

TNK1

561

Q13470