Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F3 CYP4F12 CYP4F11

4.11e-075703GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F3 CYP4F12 CYP4F11

1.43e-067703GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F3 CYP4F12 CYP4F11

1.43e-067703GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F3 CYP4F12 CYP4F11

4.86e-0610703GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F3 CYP4F12 CYP4F11

4.86e-0610703GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F3 CYP4F12 CYP4F11

4.86e-0610703GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F3 CYP4F12 CYP4F11

1.15e-0513703GO:0016713
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A1 COL4A3 COL4A5 COL5A1

2.02e-0546704GO:0030020
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F3 CYP4F12 CYP4F11

7.92e-0524703GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F3 CYP4F12 CYP4F11

1.14e-0427703GO:0008391
GeneOntologyMolecularFunctionaromatase activity

CYP4F3 CYP4F12 CYP4F11

2.49e-0435703GO:0070330
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F3 CYP4F12 CYP4F11

3.71e-0440703GO:0016709
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

5.17e-04188705GO:0005201
GeneOntologyMolecularFunctionlipid transporter activity

GRAMD1B ABCC3 ABCA6 GRAMD1A XKR8

6.25e-04196705GO:0005319
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F3 CYP4F12 CYP4F11

6.77e-0449703GO:0016712
GeneOntologyMolecularFunctionplatelet-derived growth factor binding

COL4A1 COL5A1

7.82e-0412702GO:0048407
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A8 SLC39A14

9.22e-0413702GO:0140410
GeneOntologyMolecularFunctionarachidonate binding

CYP4F12 CYP4F11

1.24e-0315702GO:0050544
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A18 ABCC3 SLC4A8 ABCA6 SLC39A14 NDUFA10 SLC35B1

1.39e-03477707GO:0022804
GeneOntologyMolecularFunctionicosanoid binding

CYP4F12 CYP4F11

1.41e-0316702GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F12 CYP4F11

1.41e-0316702GO:0050543
GeneOntologyMolecularFunctiontransporter activity

SLC6A18 GRAMD1B SLC41A2 ABCC3 SLC4A8 ABCA6 GRAMD1A XKR8 SLC39A14 NDUFA10 SLC14A2 SLC35B1

1.62e-0312897012GO:0005215
GeneOntologyMolecularFunctioncholesterol transfer activity

GRAMD1B GRAMD1A

3.18e-0324702GO:0120020
GeneOntologyMolecularFunctionsterol transfer activity

GRAMD1B GRAMD1A

3.45e-0325702GO:0120015
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A18 SLC39A14

3.73e-0326702GO:0015296
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F12 CYP4F11

4.32e-0328702GO:0036041
GeneOntologyBiologicalProcesscollagen-activated tyrosine kinase receptor signaling pathway

COL4A1 COL4A3 GP6 COL4A5

6.25e-0812714GO:0038063
GeneOntologyBiologicalProcesscollagen-activated signaling pathway

COL4A1 COL4A3 GP6 COL4A5

3.80e-0718714GO:0038065
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F3 CYP4F12 CYP4F11

7.76e-076713GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F3 CYP4F12 CYP4F11

1.35e-067713GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F3 CYP4F12 CYP4F11

2.16e-068713GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F3 CYP4F12 CYP4F11

6.32e-0611713GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F3 CYP4F12 CYP4F11

8.41e-0612713GO:0042758
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F12 CYP4F11

3.50e-053712GO:0042361
GeneOntologyBiologicalProcessextracellular matrix organization

COL4A1 COL4A3 COL4A5 COL5A1 ADAMTS7 HAPLN2 LAMB3 SMAD3

4.51e-05377718GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL4A1 COL4A3 COL4A5 COL5A1 ADAMTS7 HAPLN2 LAMB3 SMAD3

4.59e-05378718GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL4A1 COL4A3 COL4A5 COL5A1 ADAMTS7 HAPLN2 LAMB3 SMAD3

4.68e-05379718GO:0045229
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F3 CYP4F12 CYP4F11

5.74e-0522713GO:1901569
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

ACSM1 CYP4F3 CYP4F12 CYP4F11 DAGLA

6.87e-05124715GO:0001676
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F12 CYP4F11

6.98e-054712GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F12 CYP4F11

6.98e-054712GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F12 CYP4F11

6.98e-054712GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F12 CYP4F11

6.98e-054712GO:0042377
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F3 CYP4F12 CYP4F11 DAGLA

8.89e-0568714GO:0019369
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F12 CYP4F11

1.74e-046712GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F12 CYP4F11

1.74e-046712GO:0062232
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F3 CYP4F12 CYP4F11

3.79e-0441713GO:0006691
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP4F3 CYP4F12 ALDH1A3 CYP4F11 DAGLA

3.91e-04180715GO:0120254
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F12 CYP4F11

6.30e-0411712GO:0042373
GeneOntologyBiologicalProcessfatty acid catabolic process

LPIN2 CYP4F3 CYP4F12 CYP4F11

6.90e-04116714GO:0009062
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F12 CYP4F11

7.54e-0412712GO:0042363
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A1 COL4A3 COL4A5 COL5A1

7.41e-0721724GO:0098644
GeneOntologyCellularComponentcollagen type IV trimer

COL4A1 COL4A3 COL4A5

7.78e-076723GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A1 COL4A3 COL4A5

2.17e-068723GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A1 COL4A3 COL4A5

2.17e-068723GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A1 COL4A3 COL4A5

2.17e-068723GO:0098645
GeneOntologyCellularComponentbasement membrane

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

6.38e-05122725GO:0005604
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL4A1 COL4A3 COL4A5 COL5A1 ADAMTS7 CERCAM F5

1.46e-04332727GO:0005788
GeneOntologyCellularComponentcollagen trimer

COL4A1 COL4A3 COL4A5 COL5A1

2.42e-0488724GO:0005581
GeneOntologyCellularComponentendoplasmic reticulum-plasma membrane contact site

GRAMD1B GRAMD1A

8.90e-0413722GO:0140268
GeneOntologyCellularComponentapical part of cell

SLC6A18 SLC4A8 CYP4F3 CYP4F12 SLC39A14 NEDD1 SLC14A2 CYP4F11

9.60e-04592728GO:0045177
GeneOntologyCellularComponentapical plasma membrane

SLC6A18 SLC4A8 CYP4F3 CYP4F12 SLC39A14 SLC14A2 CYP4F11

1.42e-03487727GO:0016324
GeneOntologyCellularComponentextracellular matrix

COL4A1 COL4A3 COL4A5 COL5A1 ADAMTS7 HAPLN2 LAMB3 CRISP3

1.84e-03656728GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A1 COL4A3 COL4A5 COL5A1 ADAMTS7 HAPLN2 LAMB3 CRISP3

1.88e-03658728GO:0030312
HumanPhenoLenticonus

COL4A3 COL4A5 PRPH2

9.45e-0610233HP:0001142
HumanPhenoGlomerular basement membrane lamellation

COL4A3 COL4A5

5.84e-053232HP:0030034
HumanPhenoAbnormality of lens shape

COL4A3 COL4A5 PRPH2

6.28e-0518233HP:0011526
HumanPhenoProlonged bleeding time

MPL GP6 COL5A1 F5

6.34e-0550234HP:0003010
MousePhenoabnormal renal glomerulus basement membrane morphology

COL4A1 COL4A3 COL4A5 SMAD3

3.91e-0544614MP:0011348
MousePhenohematuria

COL4A1 COL4A3 COL4A5

7.29e-0519613MP:0005161
MousePhenoabnormal lens capsule morphology

COL4A1 COL4A5 LIM2

8.55e-0520613MP:0003236
DomainC4

COL4A1 COL4A3 COL4A5

1.00e-066703SM00111
Domain-

COL4A1 COL4A3 COL4A5

1.00e-0667032.170.240.10
DomainCollagen_VI_NC

COL4A1 COL4A3 COL4A5

1.00e-066703IPR001442
DomainC4

COL4A1 COL4A3 COL4A5

1.00e-066703PF01413
DomainNC1_IV

COL4A1 COL4A3 COL4A5

1.00e-066703PS51403
DomainVAST

GRAMD1B GRAMD1A

4.14e-053702PS51778
DomainDUF4782

GRAMD1B GRAMD1A

4.14e-053702IPR031968
DomainDUF4782

GRAMD1B GRAMD1A

4.14e-053702PF16016
DomainCTDL_fold

COL4A1 COL4A3 COL4A5 HAPLN2 KLRG1

5.06e-05107705IPR016187
DomainCollagen

COL4A1 COL4A3 COL4A5 COL5A1

2.91e-0485704IPR008160
DomainCollagen

COL4A1 COL4A3 COL4A5 COL5A1

2.91e-0485704PF01391
DomainCyt_P450_E_grp-I

CYP4F3 CYP4F12 CYP4F11

6.39e-0445703IPR002401
DomainCyt_P450_CS

CYP4F3 CYP4F12 CYP4F11

1.03e-0353703IPR017972
DomainCYTOCHROME_P450

CYP4F3 CYP4F12 CYP4F11

1.28e-0357703PS00086
Domain-

CYP4F3 CYP4F12 CYP4F11

1.34e-03587031.10.630.10
Domainp450

CYP4F3 CYP4F12 CYP4F11

1.34e-0358703PF00067
DomainCyt_P450

CYP4F3 CYP4F12 CYP4F11

1.48e-0360703IPR001128
DomainGRAM

GRAMD1B GRAMD1A

1.61e-0316702SM00568
Domain-

PIK3C3 TRRAP

1.61e-03167021.10.1070.11
DomainPI3Kc

PIK3C3 TRRAP

1.61e-0316702SM00146
DomainPI3/4_kinase_cat_dom

PIK3C3 TRRAP

2.04e-0318702IPR000403
DomainPI3_PI4_kinase

PIK3C3 TRRAP

2.04e-0318702PF00454
DomainPI3_4_KINASE_3

PIK3C3 TRRAP

2.04e-0318702PS50290
DomainPI3_4_KINASE_1

PIK3C3 TRRAP

2.04e-0318702PS00915
DomainPI3_4_KINASE_2

PIK3C3 TRRAP

2.04e-0318702PS00916
DomainGRAM

GRAMD1B GRAMD1A

3.05e-0322702PF02893
DomainGRAM

GRAMD1B GRAMD1A

3.05e-0322702IPR004182
DomainHormR

GIPR CALCRL

3.93e-0325702SM00008
DomainHRM

GIPR CALCRL

4.91e-0328702PF02793
DomainGPCR_2_secretin-like_CS

GIPR CALCRL

7.19e-0334702IPR017983
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A1 COL4A3 COL4A5 LAMB3

2.95e-0715564M27161
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A1

1.03e-0620564MM15061
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A3 COL4A5 F5

1.87e-0623564M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A3 COL4A5 F5

1.87e-0623564MM1427
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

3.50e-0659565M27218
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

4.14e-0661565M27103
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A3 COL4A5 LAMB3

5.67e-0630564M27216
PathwayPID_INTEGRIN1_PATHWAY

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

6.13e-0666565M18
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A3 COL4A5

6.99e-0610563M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A3 COL4A5

6.99e-0610563MM1560
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A1

7.39e-0632564MM14924
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A3 COL4A5

9.58e-0611563M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A3 COL4A5

1.27e-0512563MM1526
PathwayREACTOME_EICOSANOIDS

CYP4F3 CYP4F12 CYP4F11

1.27e-0512563M27129
PathwayREACTOME_EICOSANOIDS

CYP4F3 CYP4F12 CYP4F11

1.27e-0512563MM14845
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A3 COL4A5 COL5A1

1.49e-0538564MM14969
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A3 COL4A5

1.65e-0513563MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A3 COL4A5

1.65e-0513563M12950
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A3 COL4A5 COL5A1

2.03e-0541564MM15538
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A3 COL4A5

2.10e-0514563MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A3 COL4A5

2.10e-0514563M6487
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F3 CYP4F12 CYP4F11

2.10e-0514563MM15842
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A1

2.23e-0542564M7169
PathwayREACTOME_FATTY_ACIDS

CYP4F3 CYP4F12 CYP4F11

2.61e-0515563M27126
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A3 COL4A5

2.61e-0515563MM14922
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A3 COL4A5 COL5A1

2.69e-0544564M27812
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

2.80e-0590565M631
PathwayPID_SYNDECAN_1_PATHWAY

COL4A1 COL4A3 COL4A5 COL5A1

3.22e-0546564M198
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A3 COL4A5 COL5A1

4.49e-0550564MM14796
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A3 COL4A5

4.64e-0518563M27164
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F3 CYP4F12 CYP4F11

4.64e-0518563MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F3 CYP4F12 CYP4F11

4.64e-0518563MM14841
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A3 COL4A5

4.64e-0518563MM14882
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A3 COL4A5 COL5A1

5.66e-0553564MM14566
PathwayBIOCARTA_AMI_PATHWAY

COL4A1 COL4A3 COL4A5

6.45e-0520563M15394
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A3 COL4A5 COL5A1

7.54e-0557564MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A3 COL4A5 COL5A1

8.08e-0558564M2049
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A3 COL4A5 COL5A1

9.85e-0561564MM14637
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A3 COL4A5 COL5A1

1.12e-0463564M11187
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A3 COL4A5 COL5A1

1.19e-0464564M26953
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F3 CYP4F12 CYP4F11

1.28e-0425563MM14858
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A3 COL4A5 COL5A1

1.42e-0467564M26999
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A1 COL4A3 COL4A5 COL5A1

2.09e-0474564M160
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3

2.29e-04140565M587
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A18 SLC41A2 SLC39A14 SLC14A2

2.32e-0476564MM15072
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A1

2.32e-0476564MM14867
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A1 COL4A3 COL4A5 COL5A1

2.32e-0476564M27219
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A3 COL4A5 COL5A1

2.32e-0476564MM14573
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F3 CYP4F12 CYP4F11

2.98e-0433563MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F3 CYP4F12 CYP4F11

2.98e-0433563MM15963
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A18 SLC41A2 SLC39A14 SLC14A2

3.40e-0484564M27334
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL4A1 GP6 COL5A1 LAMB3

3.40e-0484564M7098
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A1

3.56e-0485564M16441
PathwayWP_SMALL_CELL_LUNG_CANCER

COL4A1 COL4A3 COL4A5 LAMB3

5.66e-0496564M39834
PathwayPID_INTEGRIN3_PATHWAY

COL4A1 COL4A3 COL4A5

6.55e-0443563M53
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F12 CYP4F11

8.33e-0411562MM14863
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F3 CYP4F11

9.97e-0412562M27128
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A1 COL4A3 COL4A5 COL5A1

1.08e-03114564MM14571
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F3 CYP4F12 CYP4F11

1.82e-0361563MM14861
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F3 CYP4F12 CYP4F11

1.90e-0362563M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F3 CYP4F12 CYP4F11

2.08e-0364563M5650
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F3 CYP4F12 CYP4F11

2.28e-0366563MM14839
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A18 SLC41A2 SLC4A8 SLC39A14 SLC14A2

2.49e-03238565MM15076
PathwayREACTOME_METAL_ION_SLC_TRANSPORTERS

SLC41A2 SLC39A14

2.81e-0320562MM15077
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A18 SLC41A2 SLC4A8 SLC39A14 SLC14A2

3.03e-03249565M5988
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F3 CYP4F11

3.10e-0321562M27137
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

GPBAR1 GIPR ADCY4 CALCRL

3.47e-03157564M4904
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

COL4A1 COL4A3 COL4A5 COL5A1 KRTAP13-4 MARS1 SMAD3

3.57e-03502567MM14537
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

COL4A1 COL4A3 COL4A5 SMAD3

3.80e-03161564M39770
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

GIPR CALCRL

4.04e-0324562MM15992
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

GIPR CALCRL

4.04e-0324562M39643
PathwayREACTOME_METAL_ION_SLC_TRANSPORTERS

SLC41A2 SLC39A14

4.04e-0324562M18795
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

COL4A1 COL4A3 COL4A5 LAMB3

8.73e-09127348918877
Pubmed

Identification of an Altered Matrix Signature in Kidney Aging and Disease.

COL4A1 COL4A3 COL4A5

8.87e-09373334049963
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A1 COL4A3 COL4A5 LAMB3

2.40e-08157349264260
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F3 CYP4F12 CYP4F11

3.54e-08473318065749
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL4A1 GRAMD1B COL4A5 COL5A1 ABCC3 XPO6 SURF4 GRAMD1A NAGA SEL1L3 LAMB3 CERCAM SLC39A14 PTGFRN

1.76e-071201731435696571
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A1 COL4A3 COL4A5

1.77e-0767339506531
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A1 COL4A3 COL4A5

1.77e-0767337495302
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A1 COL4A3 COL4A5

1.77e-0767332426947
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A1 COL4A3 COL4A5

1.77e-07673323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A1 COL4A3 COL4A5

1.77e-0767336811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A1 COL4A3 COL4A5

1.77e-0767336389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A1 COL4A3 COL4A5

1.77e-07673312225806
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A1 COL4A3 COL4A5

1.77e-07673310534397
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F3 CYP4F12 CYP4F11

1.77e-0767339068972
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A1 COL4A3 COL4A5

1.77e-0767339673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A1 COL4A3 COL4A5

1.77e-07673311732842
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A1 COL4A3 COL4A5

1.77e-07673319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A1 COL4A3 COL4A5

1.77e-0767336988303
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

COL4A1 COL4A3 COL4A5 LAMB3

2.58e-072673424742657
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A1 COL4A3 COL4A5

3.09e-07773310639489
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A1 COL4A3 COL4A5

3.09e-07773311711546
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A1 COL4A3 COL4A5

3.09e-0777338006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A1 COL4A3 COL4A5

3.09e-07773310416788
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A1 COL4A3 COL4A5

3.09e-07773310716744
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A1 COL4A3 COL4A5

3.09e-0777331724753
Pubmed

Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.

COL4A1 COL4A3 COL4A5

3.09e-0777337521231
Pubmed

Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals.

COL4A1 COL4A3 COL4A5

3.09e-07773317418794
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

COL4A1 COL4A5 COL5A1 LAMB3

4.08e-072973422613833
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A1 COL4A3 COL4A5

4.93e-0787333997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A1 COL4A3 COL4A5

4.93e-07873329422532
Pubmed

Mice develop normally without tenascin.

COL4A1 COL4A3 COL4A5

4.93e-0787331383086
Pubmed

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

COL4A1 COL4A3 COL4A5

4.93e-0787331377218
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A1 COL4A3 COL4A5

4.93e-07873310382266
Pubmed

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.

COL4A1 COL4A3 COL4A5

4.93e-07873310970885
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A1 COL4A3 COL4A5

7.38e-0797338562707
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A1 COL4A3 COL4A5

7.38e-0797339878537
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A1 COL4A3 COL4A5

7.38e-07973312101409
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A1 COL4A3 COL4A5

1.05e-06107339415455
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A1 COL4A3 COL4A5

1.05e-06107339136074
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A1 COL4A3 COL4A5

1.45e-061173314998921
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A1 COL4A3 COL4A5

1.45e-06117337500359
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A1 COL4A3 COL4A5

1.45e-06117339731539
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

COL4A1 COL4A3 COL4A5 LAMB3

1.54e-064073427068110
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A1 COL4A3 COL4A5

1.93e-061273312180907
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A1 COL4A3 COL4A5

1.93e-061273315837576
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A1 COL4A3 COL4A5

1.93e-061273316024816
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A1 COL4A3 COL4A5

2.50e-06137339833687
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A1 COL4A3 COL4A5

3.18e-061473312878203
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A1 COL4A3 COL4A5

3.96e-061573310625553
Pubmed

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.

COL4A1 COL4A3 COL4A5

3.96e-061573310706142
Pubmed

Distinct expression patterns of alpha1 (IV) and alpha5 (IV) collagen chains in cylindroma and malignant cylindroma.

COL4A1 COL4A5

4.35e-06273215583824
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

4.35e-06273217980168
Pubmed

Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome.

COL4A3 COL4A5

4.35e-06273235177655
Pubmed

Mutation detection of COL4An gene based on mRNA of peripheral blood lymphocytes and prenatal diagnosis of Alport syndrome in China.

COL4A3 COL4A5

4.35e-06273221143337
Pubmed

Prevalence Estimates of Predicted Pathogenic COL4A3-COL4A5 Variants in a Population Sequencing Database and Their Implications for Alport Syndrome.

COL4A3 COL4A5

4.35e-06273234400539
Pubmed

Possible Digenic Disease in a Caucasian Family with COL4A3 and COL4A5 Mutations.

COL4A3 COL4A5

4.35e-06273230661074
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

4.35e-06273215364545
Pubmed

Spectrum of clinical features and type IV collagen alpha-chain distribution in Chinese patients with Alport syndrome.

COL4A3 COL4A5

4.35e-06273216940319
Pubmed

Guidelines for Genetic Testing and Management of Alport Syndrome.

COL4A3 COL4A5

4.35e-06273234930753
Pubmed

Expression and Clinical Significance of KLRG1 and 2B4 on T Cells in the Peripheral Blood and Tumour of Patients with Cervical Cancer.

CD244 KLRG1

4.35e-06273233401997
Pubmed

Discordance between skin biopsy and kidney biopsy in an X-linked carrier of Alport syndrome.

COL4A3 COL4A5

4.35e-06273217294221
Pubmed

Aster Proteins Regulate the Accessible Cholesterol Pool in the Plasma Membrane.

GRAMD1B GRAMD1A

4.35e-06273232719109
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A1 COL4A3 COL4A5

4.87e-061673315878328
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLC6A18 COL4A1 SLC41A2 SLC4A8 SLC14A2 SLC35B1

5.79e-0621273619521566
Pubmed

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.

COL4A1 COL4A3 COL4A5

7.08e-06187339160753
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL4A1 COL4A3 COL4A5

8.39e-061973315689378
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

COL4A1 COL4A3 COL4A5 COL5A1

9.09e-066273428344315
Pubmed

The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2.

COL4A1 COL4A3 COL4A5

1.15e-052173323325811
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL4A1 COL4A3 LAMB3

1.15e-052173327856617
Pubmed

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome.

COL4A3 COL4A5

1.30e-05373227576055
Pubmed

Novel COL4A5, COL4A4, and COL4A3 mutations in Alport syndrome.

COL4A3 COL4A5

1.30e-05373215954103
Pubmed

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure.

COL4A3 COL5A1

1.30e-05373214676276
Pubmed

Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

COL4A1 COL4A3

1.30e-0537323025878
Pubmed

Alport syndrome: impact of digenic inheritance in patients management.

COL4A3 COL4A5

1.30e-05373227859054
Pubmed

Sixteen novel mutations identified in COL4A3, COL4A4, and COL4A5 genes in Slovenian families with Alport syndrome and benign familial hematuria.

COL4A3 COL4A5

1.30e-05373217396119
Pubmed

A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers.

COL4A3 COL4A5

1.30e-05373224522496
Pubmed

The localization and secretion of type IV collagen in synovial capillaries by immunohistochemistry using a monoclonal antibody against human type IV collagen.

COL4A1 COL4A5

1.30e-0537326386565
Pubmed

Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches.

COL4A3 COL4A5

1.30e-0537327962065
Pubmed

Novel mutations in COL4A3, COL4A4, and COL4A5 in Chinese patients with Alport Syndrome.

COL4A3 COL4A5

1.30e-05373228542346
Pubmed

Collagen Family Genes Associated with Risk of Recurrence after Radiation Therapy for Vestibular Schwannoma and Pan-Cancer Analysis.

COL4A1 COL5A1

1.30e-05373234691289
Pubmed

Autosomal dominant form of type IV collagen nephropathy exists among patients with hereditary nephritis difficult to diagnose clinicopathologically.

COL4A3 COL4A5

1.30e-05373228704582
Pubmed

Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.

COL4A3 COL4A5

1.30e-05373218930919
Pubmed

Integration of Genetic Testing and Pathology for the Diagnosis of Adults with FSGS.

COL4A3 COL4A5

1.30e-05373230647093
Pubmed

Four novel mutations identified in the COL4A3, COL4A4 and COL4A5 genes in 10 families with Alport syndrome.

COL4A3 COL4A5

1.30e-05373238978054
Pubmed

Alport Syndrome

COL4A3 COL4A5

1.30e-05373220301386
Pubmed

Pathogenicity of a Human Laminin β2 Mutation Revealed in Models of Alport Syndrome.

COL4A3 COL4A5

1.30e-05373229263159
Pubmed

Genetic Variants of the COL4A3 , COL4A4 , and COL4A5 Genes Contribute to Thinned Glomerular Basement Membrane Lesions in Sporadic IgA Nephropathy Patients.

COL4A3 COL4A5

1.30e-05373236130833
Pubmed

A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.

COL4A3 COL4A5

1.30e-05373214507670
Pubmed

Genetic diagnosis of Alport syndrome in 16 Chinese families.

COL4A3 COL4A5

1.30e-05373238433557
Pubmed

Evidence of digenic inheritance in Alport syndrome.

COL4A3 COL4A5

1.30e-05373225575550
Pubmed

COL4A6 is dispensable for autosomal recessive Alport syndrome.

COL4A3 COL4A5

1.30e-05373227377778
Pubmed

Functional interaction between COL4A1/COL4A2 and SMAD3 risk loci for coronary artery disease.

COL4A1 SMAD3

1.30e-05373226310581
Pubmed

Unbiased next generation sequencing analysis confirms the existence of autosomal dominant Alport syndrome in a relevant fraction of cases.

COL4A3 COL4A5

1.30e-05373224033287
Pubmed

Characterization of assembly of recombinant type IV collagen alpha3, alpha4, and alpha5 chains in transfected cell strains.

COL4A3 COL4A5

1.30e-05373214633121
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

COL4A1 COL4A3 COL4A5 LAMB3

2.38e-057973418757743
Pubmed

Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.

COL4A1 COL4A3

2.60e-0547327827955
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F12 CYP4F11

2.60e-05473222665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F12 CYP4F11

2.60e-05473211185557
Pubmed

Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.

GP6 F5

2.60e-05473219278955
Pubmed

Two-hybrid analysis reveals multiple direct interactions for thrombospondin 1.

COL5A1 LAMB3

2.60e-0547329840442
InteractionMMP9 interactions

COL4A1 COL4A3 COL4A5 COL5A1 SMAD3

3.57e-0667705int:MMP9
InteractionDCN interactions

COL4A1 COL4A3 COL4A5 COL5A1

1.49e-0543704int:DCN
Cytoband19p13.1

CYP4F12 CYP4F11

2.68e-034873219p13.1
Cytoband16p11.2

PPP4C ASPHD1 XPO6

3.56e-0319173316p11.2
GeneFamilyCollagens

COL4A1 COL4A3 COL4A5 COL5A1

1.31e-0546574490
GeneFamilyCytochrome P450 family 4

CYP4F3 CYP4F12 CYP4F11

1.97e-04365731003
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

GRAMD1B GRAMD1A

7.45e-04135721146
GeneFamilySolute carriers

SLC6A18 SLC41A2 SLC4A8 SLC39A14 SLC14A2 SLC35B1

1.48e-03395576752
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A1 COL4A3 COL4A5 LAMB3

4.45e-0723724M48001
CoexpressionGU_PDEF_TARGETS_UP

COL4A1 COL4A5 COL5A1 PIK3C3 SMAD3

1.54e-0671725M3955
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A1 COL4A3 COL4A5 LAMB3

4.44e-0640724M5887
CoexpressionNABA_COLLAGENS

COL4A1 COL4A3 COL4A5 COL5A1

5.96e-0643724MM17060
CoexpressionNABA_COLLAGENS

COL4A1 COL4A3 COL4A5 COL5A1

6.54e-0644724M3005
CoexpressionBILBAN_B_CLL_LPL_UP

FRY ABCA6 SLC39A14 TRRAP

2.94e-0564724M19930
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 GIPR FRY LPIN2 LAMB3 ALDH1A3 SLC14A2

1.90e-0818073749829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A1 COL4A3 COL5A1 ABCA6 ACSM1 CALCRL SMAD3

2.86e-0819173770c067c54084bfb02c29bab085f4defd477194fb
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL4A1 COL4A3 COL5A1 ABCA6 ACSM1 CALCRL SMAD3

2.97e-08192737356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

COL4A1 COL4A3 COL5A1 ABCA6 ACSM1 CALCRL SMAD3

3.18e-0819473711c79a8c56ece42713b04b321982e41e239f07a5
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A1 COL4A3 COL5A1 ABCA6 ACSM1 CALCRL SMAD3

3.30e-08195737ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 COL4A5 COL5A1 LAMB3 TDRD1

2.77e-0716273657d627259d27f39885bf416d74bcb6656db6e27b
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 ADCY4 TMEM204 ADAMTS7 CALCRL TM4SF19

5.14e-07180736efc4c5a4dea456527526bbfd88cf70d803893671
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A1 COL4A3 COL5A1 ABCA6 ACSM1 CALCRL

7.05e-0719073612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 SLC41A2 COL5A1 ABCC3 SEL1L3 SMAD3

7.50e-071927368b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 TMEM204 GRAMD1A CALCRL SLC39A14

7.73e-07193736c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL4A1 COL4A3 COL5A1 ABCA6 ACSM1 CALCRL

7.73e-07193736dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 TMEM204 GRAMD1A CALCRL SLC39A14

7.73e-07193736682ce63b73a7d02eef240673db67058d7507f744
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

COL4A1 COL4A3 ABCA6 SLC39A14 ALDH1A3 SMAD3

7.96e-07194736803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 TMEM204 GRAMD1A CALCRL SLC39A14

8.21e-0719573653b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 FRY TMEM204 CALCRL TDRD1

9.24e-071997360602e2b2aa56d106da63bd342a38bef437b4d496
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CERCAM ALDH1A3 SLC14A2 TM4SF19

4.08e-061457358da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 SEL1L3 ALDH1A3 SLC14A2

4.98e-0615173516fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A1 COL5A1 ADAMTS7 SLC39A14 SLC14A2

6.60e-061607358a4746463ca1976f7d6de803496c851249ced797
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GRAMD1B COL4A5 TMEM243 HDAC8 KLRG1

7.22e-0616373513f76f2979558f5cd27fbfd1659b413b3cac18f5
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A18 GRAMD1B COL4A3 ABCC3 ACSM1

8.13e-06167735ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A18 GRAMD1B COL4A3 ABCC3 ACSM1

8.61e-06169735f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ASPHD1 ACSM1 ALDH1A3 F5 CYP4F11

9.64e-06173735e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

ASPHD1 ACSM1 ALDH1A3 F5 CYP4F11

9.64e-0617373574ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A1 ASPHD1 TMEM204 CALCRL SLC39A14

1.02e-05175735f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell368C-Endothelial_cells-Endothelial-E|368C / Donor, Lineage, Cell class and subclass (all cells)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.17e-051807358ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A5 COL5A1 CERCAM DAGLA

1.17e-0518073539ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell368C-Endothelial_cells-Endothelial-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.17e-05180735394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ACP6 XPO6 NAGA TRRAP FAM200B

1.27e-05183735807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL5A1 SEL1L3 CERCAM ALDH1A3

1.30e-05184735da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCelldroplet-Fat-Mat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 FRY TMEM204 MYO10 CALCRL

1.33e-05185735d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ACP6 XPO6 NAGA TRRAP FAM200B

1.37e-0518673576cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCellfacs-Heart-LV-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 ADCY4 TMEM204 MYO10 CALCRL

1.40e-051877351bc338c22d645a854f8d8eb8a064c441121fb673
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 ADCY4 TMEM204 CALCRL SLC39A14

1.44e-051887355959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCellPND07-28-samps-Endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL4A1 ADCY4 TMEM204 MYO10 CALCRL

1.48e-05189735eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD1B ADCY4 CALCRL ALDH1A3 F5

1.48e-05189735b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL4A1 ADCY4 TMEM204 MYO10 CALCRL

1.48e-05189735d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 ADCY4 FRY TMEM204 MYO10

1.52e-0519073589d1d686cc683206534e2157554d7d0df5d53497
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 TMEM204 CALCRL TDRD1

1.52e-0519073506bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 ADCY4 FRY TMEM204 MYO10

1.52e-0519073565ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCellFibroblasts-CD55+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL4A1 ADAMTS7 SLC39A14 ALDH1A3 F5

1.63e-051937358f4bf9a2fbedae35432dad96730b00c70185874c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL5A1 CERCAM ALDH1A3 SLC14A2

1.63e-051937350f2167eef8203a5659c8c72e4e77646003d64797
ToppCellsevere-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

XPO6 SEL1L3 XKR8 CYP4F3 F5

1.63e-05193735f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 TMEM204 MYO10 CALCRL PTGFRN

1.63e-051937352483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 ADCY4 TMEM204 MYO10 CALCRL

1.68e-051947356115c20ffe414378508f3879e67815b6062341a7
ToppCellPND28-Endothelial-Endothelial_blood-vessel|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 ADCY4 TMEM204 MYO10 CALCRL

1.68e-051947356317e9cdf96eb020f84d50bf41f803db5c9c04a0
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

COL4A1 COL4A3 ABCA6 ACSM1 CALCRL

1.68e-05194735014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 FRY TMEM204 MYO10 CALCRL

1.68e-05194735ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellPND28-Endothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 ADCY4 TMEM204 MYO10 CALCRL

1.68e-05194735b592c713204db7ae2f34a54f2d03d13834593c57
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 FRY TMEM204 MYO10 CALCRL

1.68e-05194735cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCell367C-Endothelial_cells-Endothelial-E-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.72e-0519573565fc50e3818e902028fc4226070fa57609c66b9c
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

COL4A3 COL5A1 ABCA6 ACSM1 SMAD3

1.72e-05195735f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A3 COL5A1 ABCA6 ACSM1 SMAD3

1.72e-05195735a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell367C-Endothelial_cells-Endothelial-E|367C / Donor, Lineage, Cell class and subclass (all cells)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.72e-051957353b79e6bb525b17192ecec9e1227a29c419968144
ToppCelldroplet-Limb_Muscle-MUSCLE-1m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A5 COL5A1 KLHL21 CERCAM

1.72e-05195735fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL5A1 ADCY4 TMEM204 TDRD1

1.76e-0519673512d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 TMEM204 CALCRL TDRD1

1.76e-05196735ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A1 ABCA6 MYO10 SLC39A14 ALDH1A3

1.80e-05197735fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 TMEM204 CALCRL TDRD1

1.80e-0519773562c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCelltumor_Lung-Endothelial_cells|tumor_Lung / Location, Cell class and cell subclass

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.80e-051977356870b311c54a73723768276a58456620f5217d43
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 FRY TMEM204 ADAMTS7

1.80e-05197735a312d9cf4ced949307eb9620be4eed926300b892
ToppCell(4)_Blood_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.80e-051977351b82979a41ef46c814c82527a585900586d71260
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A5 COL5A1 CERCAM CALCRL

1.80e-0519773586145bc1e585b4ae136e755cafd6579da2abfa65
ToppCell(4)_Endothelial_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.80e-05197735dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 TMEM204 CALCRL TDRD1

1.80e-0519773516f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCell(6)_Endothelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.85e-05198735f38f49d532fa6211f57e36ee494478bdd3f4f89c
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.85e-051987355228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.85e-0519873597ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A5 COL5A1 CERCAM PTGFRN

1.85e-051987350dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell(6)_Endothelial-A_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.85e-0519873544f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A5 COL5A1 CERCAM PTGFRN

1.85e-05198735b086af292a508a156266c2d899ba1caf820bf61c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 COL5A1 SURF4 CERCAM PTGFRN

1.85e-051987351b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.85e-051987355e274f29cc796dae7d64d6035e904816c25f9914
ToppCell(6)_Endothelial-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.85e-05198735a5e1b321376caf262ea48904d31afd1b8e9d3be2
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.89e-051997356cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.89e-0519973582758d0cee9387d002e3f68a6faa324134fb7564
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL4A3 COL4A5 LPIN2 LAMB3 CERCAM

1.89e-05199735a270630626df614f8605abddb7dee7c4d74f6149
ToppCell3'-Parenchyma_lung-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.89e-05199735920299626a9ec8e50d944f5a7667e855de7edd72
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.89e-05199735ddfb725ccbcadbd188e20b60a7567e1f8245f18d
ToppCellnormal_Lung-Endothelial_cells|normal_Lung / Location, Cell class and cell subclass

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.89e-051997356dff5e10370d2b43afe6e3428f5f3aa37ccc32ff
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 TMEM204 ADAMTS7 CALCRL

1.89e-05199735463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellTracheal-10x3prime_v2-Endothelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-052007352e51195810bca8a98488a8a06c538feaa27f1f28
ToppCelldistal-1-Endothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-052007358f25b27c10e89cf9d0091bd53c24ce63ed7d6222
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-0520073530dc7ffef2052ee8610cdca952ca12f240bcec50
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADCY4 SEL1L3 CALCRL ALDH1A3 F5

1.94e-0520073577ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCelldistal-Endothelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-05200735b17c9607d4986f8f1facc6b564d4c15c48e58915
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-05200735ec92fe4eafe527d351ee73c9735e96855ac506a3
ToppCelldistal-2-Endothelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-05200735bc1781cff7a4602057a59ef65cf16c3a9459c628
ToppCelldistal-3-Endothelial|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-05200735c000264843f611a28a473b5a92195b163f46c4f4
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

ADCY4 FRY CALCRL ALDH1A3 F5

1.94e-05200735b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 ADCY4 FRY TMEM204 CALCRL

1.94e-05200735061ba851f941c616ddb462512e826c412881c3ce
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 GIPR ALDH1A3 SLC14A2

6.78e-05133734f303ab771482281d8793974f9f5279cee09431fe
ToppCellP03-Hematopoietic|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MPL GP6 CD244 F5

8.51e-051417344a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

ACP6 BPIFC YWHAH-AS1 KLRG1

9.99e-051477344ba9a86ab7033688a9a2a2dc84c001a49af835b4
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MPL GP6 CD244 F5

1.05e-0414973443d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MPL GP6 CD244 F5

1.05e-041497341c5a2572741c47246d455c865e8e1677c9f49598
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

ACP6 XPO6 TRRAP FAM200B

1.23e-04155734a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GP6 ABCC3 BPIFC CMTM7

1.23e-0415573493bfcf5c12cbb61a1e0444312afd2aa411a8bf50
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CALCRL ALDH1A3 SLC14A2 SMAD3

1.23e-0415573477fdae85d36efb776db977eb424b32487ef222e4
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MPL GP6 CRISP3 SUCNR1

1.26e-04156734c380142e49b1e4ecacbf37587aafa57f8562b6ad
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIM2 CD244 KLRG1 DAGLA

1.35e-04159734d2de9391b00b6c47f5fe28a1bad6da2097107ee0
DrugMadecassol

COL4A1 COL4A3 COL4A5 COL5A1 SMAD3

3.40e-0746725CID000108062
Drug12(S)-hydroxyeicosatetraenoic acid

COL4A1 COL4A3 COL4A5 COL5A1 ADCY4 PIK3C3 CYP4F12

2.27e-06189727CID000001413
DrugVitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MPL GP6 GIPR LIM2 ADAMTS7 PRPH2 CYP4F12

3.09e-061987274413_UP
DrugGK-101

COL4A1 COL4A3 COL4A5 COL5A1

5.02e-0636724CID000161853
Drughalofuginone lactate

COL4A1 COL4A3 COL4A5 COL5A1 SMAD3

7.40e-0685725CID000062891
DrugAC1L18QD

MPL COL4A1 COL4A3 GP6 COL4A5 COL5A1 ADCY4 PRPH2

8.56e-06325728CID000000213
Drugtienilic acid

ABCC3 ADCY4 CYP4F3 CYP4F12 CYP4F11

1.15e-0593725CID000038409
DrugTaurochenodeoxycholic Acid

GPBAR1 ABCC3 SMAD3

1.34e-0515723ctd:D013655
Drugd-indobufen

COL4A1 COL4A3 COL4A5 COL5A1

1.90e-0550724CID000044562
Drugridogrel

COL4A1 COL4A3 COL4A5 COL5A1

2.22e-0552724CID005362391
DrugNSC49633

COL4A1 COL4A3 COL4A5 COL5A1

2.39e-0553724CID000023340
DrugCP-331

COL4A3 COL4A5

2.95e-053722CID000130967
DrugPPACK

COL4A1 COL4A3 GP6 COL4A5 COL5A1

2.96e-05113725CID003036757
Drugperfluorodecalin

GPBAR1 PPP4C PRPH2

3.33e-0520723CID000009386
Drugdimethylnitrosamine

COL4A3 COL4A5 ABCC3 MARS1 PRPH2 F5

3.67e-05196726CID000006124
DrugBezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A

GIPR ABCC3 ADAMTS7 PRPH2 CYP4F12 KLRG1

3.78e-051977262630_UP
DrugIsometheptene mucate; Up 200; 8.2uM; PC3; HT_HG-U133A

ABCC3 FRY ASPHD1 ADAMTS7 TDRD1 DAGLA

3.78e-051977265082_UP
Drugbenzphetamine

CD244 CYP4F3 CYP4F12 SLC14A2 CYP4F11

3.79e-05119725CID000002341
DrugDicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

COL5A1 ABCC3 SYNRG MARS1 LPIN2 SMAD3

3.89e-051987263423_DN
DrugAC1LAKND

COL4A1 COL4A3 COL4A5 COL5A1

4.46e-0562724CID000470146
DrugBrn 2557402

COL4A3 COL4A5

5.89e-054722CID000042742
Drug2f1b

COL4A3 COL4A5 LAMB3 SLC14A2

6.06e-0567724CID011963508
Drugpropoxyphene

PPP4C CYP4F3 CYP4F12 CYP4F11

6.06e-0567724CID000010100
DrugBAPN

COL4A1 COL4A3 COL4A5 COL5A1

7.61e-0571724CID000001647
Drugmalotilate

COL4A1 COL4A3 COL4A5 COL5A1

7.61e-0571724CID000004006
DrugDL-penicillamine

COL4A1 COL4A3 COL4A5 COL5A1 SLC39A14

7.95e-05139725CID000004727
DrugPCR 4099

COL4A1 COL4A3 COL4A5 COL5A1 ADCY4

7.95e-05139725CID000002806
DrugAC1NMZ1B

COL4A1 COL4A3 COL4A5 COL5A1

9.43e-0575724CID005034185
Drugdimethylmalonimidate

COL4A3 COL4A5

9.80e-055722CID000189133
DrugCyclo-rgdphg

COL4A3 COL4A5

9.80e-055722CID006449872
Drugstrontium ranelate

COL4A1 COL4A3 COL4A5 COL5A1

1.04e-0477724CID006918182
Drugprostacyclin sodium salt

COL4A1 COL4A3 COL4A5 GPBAR1 COL5A1 ADCY4

1.41e-04250726CID000000159
Drug4-fluoranylproline

COL4A3 COL4A5

1.47e-046722CID000450594
Diseasecollagen disease (implicated_via_orthology)

COL4A1 COL4A3 COL4A5

2.65e-0612693DOID:854 (implicated_via_orthology)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL4A1 COL4A5 COL5A1 SMAD3

7.35e-0653694C4707243
DiseaseAlport syndrome (is_implicated_in)

COL4A3 COL4A5

1.61e-053692DOID:10983 (is_implicated_in)
DiseaseAlport syndrome

COL4A3 COL4A5

1.61e-053692cv:C1567741
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A5

1.61e-053692cv:CN076135
DiseaseHematuria, Benign Familial

COL4A3 COL4A5

3.22e-054692C0241908
DiseaseAlport Syndrome

COL4A3 COL4A5

3.22e-054692C1567741
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A5

5.36e-055692C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A5

5.36e-055692C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A5

5.36e-055692C1567744
Diseasecorneal topography

COL4A3 COL5A1 ADAMTS7 SMAD3

1.27e-04109694EFO_0004345
DiseaseHematuria

COL4A1 COL4A5

1.92e-049692C0018965
Diseaseimmunoglobulin M measurement

GRAMD1B CMTM7

1.92e-049692EFO_0020466
Diseasemyopathy (implicated_via_orthology)

COL4A1 COL4A3 COL4A5

1.96e-0448693DOID:423 (implicated_via_orthology)
DiseaseBlood Coagulation Disorders

COL5A1 F5

6.33e-0416692C0005779
Diseaseneoplasm of mature B-cells

GRAMD1B SLC14A2

9.96e-0420692EFO_0000096
Diseaseserum IgM measurement

GRAMD1B CMTM7

1.21e-0322692EFO_0004993
DiseaseRenal glomerular disease

COL4A3 COL4A5

1.32e-0323692C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A5

1.32e-0323692C4521256
Diseaseinflammatory biomarker measurement

GP6 F5

1.69e-0326692EFO_0004872
Diseasesodium measurement

GIPR ASPHD1 HDAC8

1.83e-03103693EFO_0009282

Protein segments in the cluster

PeptideGeneStartEntry
QTYYCSTACQRRDWS

TDRD1

186

Q9BXT4
GSCTTLLVYVRYAWQ

FAM200B

236

P0CF97
CNFASRNDYSYWLST

COL4A3

1511

Q01955
YAQYWDSTISSGLCI

ADAM20

381

O43506
GLYTSAYWCGQALVD

ABCA6

1051

Q8N139
GTVWINCYNALYAQA

ALDH1A3

461

P47895
ETAWALQSLGYTCYS

ADCY4

1031

Q8NFM4
IVTQYCVGANYTWLL

GIPR

221

P48546
QGRLYLSENWICFYS

GRAMD1A

121

Q96CP6
QGRLYLSENWICFYS

GRAMD1B

126

Q3KR37
YDAAPLTWSRCSRQY

ADAMTS7

421

Q9UKP4
CNFASRNDYSYWLST

COL4A1

1511

P02462
YSGYWSLCAAVNRAL

C9orf64

96

Q5T6V5
NQRSCYPYIISNRWL

ABCC3

1181

O15438
CYYAVSWLRQGFSIN

YWHAH-AS1

41

Q9Y442
CYLQTDSIAYWNATR

LIM2

51

P55344
TYNWNDCYIASGSLS

NEDD1

126

Q8NHV4
RLATYSQLYQAWTEG

HAPLN2

176

Q9GZV7
NQSRRGYWSCLLVYL

GPBAR1

76

Q8TDU6
ITCQASEGIGNYLYW

IGKV6D-41

41

A0A0C4DH26
ALTSLFLWYCYRLGS

ASPHD1

86

Q5U4P2
YRCSYQNGSLWSLPS

GP6

86

Q9HCN6
LVFCNSSSTVNWLGY

DDX28

401

Q9NUL7
NSYGSQWSPDYRCSV

MYO10

1111

Q9HD67
QWSPDYRCSVGTYNS

MYO10

1116

Q9HD67
IGYQCSRLYWSTVDA

KMT2B

1756

Q9UMN6
GNSYRLQSWLYSSRL

NDUFA10

126

O95299
YQWILCQGSNYSTCA

KLRG1

56

Q96E93
SRLYDCVWRYNSSVN

KLHL21

346

Q9UJP4
GCFLLWNLYVSSSQT

BPIFC

11

Q8NFQ6
QVVWYSSYLVGCGNA

CRISP3

141

P54108
LARVLAWTYTFYDNC

CYP4F11

31

Q9HBI6
VCNFASRNDYSYWLS

COL4A5

1526

P29400
LARILAWTYAFYNNC

CYP4F12

31

Q9HCS2
CYQSVAWQDAATGSY

COL5A1

1746

P20908
IVWLTQYYTSCNDLT

DAGLA

116

Q9Y4D2
KTWRVYQYLAADCTS

LAMB3

141

Q13751
YLASGAWQSSCYRPI

KRTAP13-4

136

Q3LI77
LARILAWTYTFYDNC

CYP4F3

31

Q08477
NWAIDRCYTGSYQLA

FRY

1221

Q5TBA9
YNLANTARCWTYLTG

HDAC8

306

Q9BY41
LDSQTYYSNFWCGIT

CERCAM

171

Q5T4B2
QASQSACYWLKGVRY

SLC39A14

316

Q15043
SCLVSRDGNVSYAWY

CD244

156

Q9BZW8
AIARSLYYNDNCWIS

CALCRL

271

Q16602
GNYYCVVSAWTKQRN

PTGFRN

511

Q9P2B2
EGTLWCSLYYITGNL

SEL1L3

836

Q68CR1
RYAYEWQRCLGSALN

SYNRG

1126

Q9UMZ2
PGSACRAWAYYSAVN

F5

1721

P12259
SNYSSWHYRSCLLPQ

RABGGTA

176

Q92696
SRACKNSTLANYLYW

PIK3C3

481

Q8NEB9
LAWISQGLYSCLETY

SLC41A2

331

Q96JW4
QRDYIDTTWNCGYLL

SURF4

51

O15260
YWSDYRDALSLQCLA

SLC4A8

466

Q2Y0W8
RTRSWLYAACSISYL

SLC35B1

81

P78383
ECQGSSAVSYFWYRQ

SLC6A18

151

Q96N87
NYGQSETGLICATYW

ACSM1

366

Q08AH1
ICVRSSLWTNYSAYS

CMTM7

61

Q96FZ5
FQYGWRCTTNENTYS

C11orf1

51

Q9H5F2
SSITACILIYWYRQG

TMEM243

71

Q9BU79
WVRGCRAALLSYYSS

PRPH2

246

P23942
FWCSISYYELNQRVG

SMAD3

231

P84022
LYPNYQSCWSLRQRT

ACP6

201

Q9NPH0
WAAQETCYQLRYTGE

MPL

416

P40238
RSYANGNWIYGDVLC

SUCNR1

81

Q9BXA5
GNWIYGDVLCISNRY

SUCNR1

86

Q9BXA5
PYTNLSWSCYLNIGA

TMEM204

161

Q9BSN7
SNTWCDLGINYYRQA

TTC37

776

Q6PGP7
QIGAWRFCLYFLSST

XPO6

41

Q96QU8
IYTGLWSYNCVLSCI

SLC14A2

341

Q15849
VWSAPNYCYRCGNVA

PPP4C

256

P60510
WYNCLTLAIYGSVDR

VIRMA

116

Q69YN4
YERLLYVTCSQNWEA

TRRAP

2471

Q9Y4A5
RQWNTLYLCGTDEYG

MARS1

301

P56192
NYLYDRSLWNSVCLE

TM4SF19

151

Q96DZ7
SGRAEYYQWVGICTS

XKR8

156

Q9H6D3
YQGTCRCAGTIYLWN

LPIN2

666

Q92539
NYSLLADICNLWRNY

NAGA

201

P17050