Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

TRPM4 ANO9 CACNA2D1 SLC36A1 ABCB7 SLC10A4 TMC6 ABCC11 PANX2 SLC1A5 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SLC16A14 SCN2A SCN3A TMCO3 ABCG8

2.94e-06118011421GO:0022857
GeneOntologyMolecularFunctiontransporter activity

TRPM4 ANO9 CACNA2D1 ATG9B SLC36A1 ABCB7 SLC10A4 TMC6 ABCC11 PANX2 SLC1A5 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SLC16A14 SCN2A SCN3A TMCO3 ABCG8

3.25e-06128911422GO:0005215
GeneOntologyMolecularFunctionL-alanine transmembrane transporter activity

SLC36A1 SLC36A2 SLC3A2

1.48e-0591143GO:0015180
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC36A1 ABCB7 SLC10A4 ABCC11 SLC1A5 SLC36A2 SLC3A2 ATP8A1 ABCC8 SLC16A14 TMCO3 ABCG8

1.83e-0547711412GO:0022804
GeneOntologyMolecularFunctionproline:proton symporter activity

SLC36A1 SLC36A2

3.23e-0521142GO:0005297
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TRPM4 ANO9 CACNA2D1 SLC36A1 SLC10A4 TMC6 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A TMCO3

4.53e-0579311415GO:0015075
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC36A1 SLC36A2 SLC3A2

4.97e-05131143GO:0015173
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A

6.30e-05141143GO:0031402
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC36A1 SLC1A5 SLC36A2 SLC3A2

8.67e-05411144GO:0015175
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC36A1 SLC36A2 SLC3A2

9.61e-05161143GO:0022858
GeneOntologyMolecularFunctionL-tyrosine transmembrane transporter activity

SLC36A1 SLC36A2

9.66e-0531142GO:0005302
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TRPM4 ANO9 CACNA2D1 SLC36A1 SLC10A4 ABCC11 SLC36A2 SLC3A2 KCNG2 ABCC8 SCN1A SCN2A SCN3A TMCO3

1.07e-0475811414GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPM4 CACNA2D1 SLC36A1 SLC10A4 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A TMCO3

1.07e-0466411413GO:0008324
GeneOntologyMolecularFunctiongated channel activity

TRPM4 ANO9 CACNA2D1 TMC6 SLC1A5 KCNG2 ABCC8 SCN1A SCN2A

1.28e-043341149GO:0022836
GeneOntologyMolecularFunctionABC-type transporter activity

ABCB7 ABCC11 ABCC8 ABCG8

1.75e-04491144GO:0140359
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC36A1 SLC10A4 ABCC11 SLC1A5 SLC36A2 SLC3A2 SLC16A14

1.87e-042071147GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC36A1 SLC10A4 ABCC11 SLC1A5 SLC36A2 SLC3A2 SLC16A14

1.93e-042081147GO:0005342
GeneOntologyMolecularFunctionchannel activity

TRPM4 ANO9 CACNA2D1 TMC6 PANX2 SLC1A5 KCNG2 ABCC8 SCN1A SCN2A SCN3A

2.10e-0452511411GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPM4 ANO9 CACNA2D1 TMC6 PANX2 SLC1A5 KCNG2 ABCC8 SCN1A SCN2A SCN3A

2.13e-0452611411GO:0022803
GeneOntologyMolecularFunctionsodium channel activity

TRPM4 SCN1A SCN2A SCN3A

2.21e-04521144GO:0005272
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPM4 CACNA2D1 SLC36A1 SLC10A4 SLC36A2 SLC3A2 KCNG2 ABCC8 SCN1A SCN2A SCN3A TMCO3

2.47e-0462711412GO:0022890
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.75e-04551144GO:0042974
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM4 CACNA2D1 SLC10A4 SLC3A2 KCNG2 ABCC8 SCN1A SCN2A SCN3A TMCO3

3.34e-0446511410GO:0046873
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCB7 ABCC11 ATP8A1 ABCC8 ABCG8

4.05e-041091145GO:0042626
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN2A SCN3A

4.28e-04261143GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A

4.28e-04261143GO:0031420
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

TRPM4 SLC10A4 SLC3A2 SCN1A SCN2A SCN3A

4.49e-041711146GO:0015081
GeneOntologyMolecularFunctionamino acid:proton symporter activity

SLC36A1 SLC36A2

4.77e-0461142GO:0005280
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

TRPM4 CACNA2D1 KCNG2 ABCC8 SCN1A SCN2A

6.24e-041821146GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

TRPM4 CACNA2D1 KCNG2 ABCC8 SCN1A SCN2A

6.61e-041841146GO:0022832
GeneOntologyMolecularFunctionL-proline transmembrane transporter activity

SLC36A1 SLC36A2

6.66e-0471142GO:0015193
GeneOntologyMolecularFunctionnuclear receptor binding

NR4A1 PRAMEF1 PRAMEF2 PRAMEF13 MED24 PRAMEF14

7.19e-041871146GO:0016922
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC36A1 SLC1A5 SLC36A2 SLC3A2

7.29e-04711144GO:0015179
GeneOntologyMolecularFunctionlipid transporter activity

ANO9 ATG9B SLC10A4 ABCC11 ATP8A1 ABCG8

9.18e-041961146GO:0005319
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.25e-03821144GO:1990756
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPM4 ANO9 CACNA2D1 TMC6 KCNG2 ABCC8 SCN1A SCN2A SCN3A

1.28e-034591149GO:0005216
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC36A1 SLC1A5 SLC36A2 SLC3A2

1.31e-03831144GO:0015101
GeneOntologyMolecularFunctionglycine transmembrane transporter activity

SLC36A1 SLC36A2

1.41e-03101142GO:0015187
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC36A1 SLC10A4 ABCC11 SLC1A5 SLC36A2 SLC3A2 SLC16A14

1.47e-032931147GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC36A1 SLC10A4 SLC1A5 SLC36A2 SLC3A2 SLC16A14 TMCO3

1.56e-032961147GO:0015291
GeneOntologyMolecularFunctionG protein-coupled receptor activity

NPBWR1 UTS2R GPR18 GPR20 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1 OR8G2P TAS2R5 MRGPRX4

1.60e-0388411413GO:0004930
GeneOntologyMolecularFunctionsymporter activity

SLC36A1 SLC10A4 SLC1A5 SLC36A2 SLC16A14

1.70e-031501145GO:0015293
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC36A1 SLC10A4 SLC36A2 SLC3A2 ATP8A1 ABCC8 TMCO3

1.72e-033011147GO:0022853
GeneOntologyMolecularFunctionenzyme-substrate adaptor activity

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.15e-03951144GO:0140767
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D5 RALGAPB ARHGEF38 HMGCR BCR ARHGEF15 TBC1D17 RASGEF1C RIC8A

2.51e-035071149GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D5 RALGAPB ARHGEF38 HMGCR BCR ARHGEF15 TBC1D17 RASGEF1C RIC8A

2.51e-035071149GO:0030695
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO9 ATG9B ATP8A1

3.09e-03511143GO:0140303
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC36A1 SLC1A5 SLC36A2 SLC3A2

3.09e-031051144GO:0015171
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM4 CACNA2D1 KCNG2 ABCC8 SCN1A SCN2A SCN3A

3.56e-033431147GO:0005261
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCB7 ABCC11 ATP8A1 ABCC8 ABCG8

3.57e-031781145GO:0015399
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCB7 ABCF3 ABCC11 MCM4 ATP8A1 ABCC8 DNAH8 ABCG8

3.81e-034411148GO:0016887
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A

4.15e-03171142GO:0099508
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

ESAM LRRC4C JAM3

5.13e-03611143GO:0098632
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D5 RALGAPB BCR ARHGEF15 TBC1D17 RIC8A

5.35e-032791146GO:0005096
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

NPBWR1 UTS2R BDKRB1 MRGPRX4

7.14e-031331144GO:0008528
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO9 ATG9B

7.56e-03231142GO:0017128
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response to non-antigenic stimulus

FFAR3 GPR42 FFAR2

1.60e-0731133GO:0002879
GeneOntologyBiologicalProcesscirculatory system process

MKKS TRPM4 CACNA2D1 UTS2R CALCA FFAR3 GPR42 HMGCR BCR SLC1A5 BDKRB1 KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A

4.99e-0773311317GO:0003013
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TRPM4 ANO9 CACNA2D1 SLC36A1 ABCB7 CALCA FFAR1 TMC6 ABCC11 PANX2 BDKRB1 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

6.13e-07111511321GO:0034220
GeneOntologyBiologicalProcessregulation of acute inflammatory response to non-antigenic stimulus

FFAR3 GPR42 FFAR2

6.38e-0741133GO:0002877
GeneOntologyBiologicalProcessmonoatomic ion transport

TRPM4 ANO9 CACNA2D1 SLC36A1 ABCB7 CALCA FFAR1 SLC10A4 TMC6 ABCC11 PANX2 BDKRB1 SLC36A2 SLC3A2 TG KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

1.27e-06137411323GO:0006811
GeneOntologyBiologicalProcessmembrane depolarization during action potential

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

1.49e-06361135GO:0086010
GeneOntologyBiologicalProcessacute inflammatory response to non-antigenic stimulus

FFAR3 GPR42 FFAR2

1.59e-0651133GO:0002525
GeneOntologyBiologicalProcessaction potential

TRPM4 CACNA2D1 FFAR3 GPR42 KCNG2 ABCC8 SCN1A SCN2A SCN3A

1.65e-062011139GO:0001508
GeneOntologyBiologicalProcessnegative regulation of blood pressure

MKKS UTS2R CALCA FFAR3 GPR42 BDKRB1

2.33e-06701136GO:0045776
GeneOntologyBiologicalProcessblood circulation

MKKS TRPM4 CACNA2D1 UTS2R CALCA FFAR3 GPR42 HMGCR BCR BDKRB1 KCNG2 ABCC8 SCN1A SCN2A SCN3A

2.56e-0664811315GO:0008015
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TRPM4 CACNA2D1 SLC36A1 ABCB7 CALCA FFAR1 BDKRB1 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

1.44e-0594211317GO:0098655
GeneOntologyBiologicalProcessmonoatomic cation transport

TRPM4 CACNA2D1 SLC36A1 ABCB7 CALCA FFAR1 SLC10A4 PANX2 BDKRB1 SLC36A2 SLC3A2 KCNG2 ATP8A1 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

1.61e-05115711319GO:0006812
GeneOntologyBiologicalProcessnegative regulation of insulin secretion

FFAR3 GPR42 FFAR2 HMGCR ABCC8

2.28e-05621135GO:0046676
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

2.28e-05621135GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

FFAR3 GPR42 SCN1A SCN2A SCN3A

2.46e-05631135GO:0019228
GeneOntologyBiologicalProcessL-alanine transport

SLC36A1 SLC36A2 SLC3A2

2.56e-05111133GO:0015808
GeneOntologyBiologicalProcessbehavior

MKKS TRPM4 UTS2R CALCA SLC10A4 HMGCR ATP8A1 TAS2R5 ABCC8 SCN1A SCN2A SCN3A VPS35 MRGPRX4 RIC8A HTT

2.81e-0589111316GO:0007610
GeneOntologyBiologicalProcesssomatic stem cell population maintenance

PRAMEF1 PRAMEF2 PRAMEF13 MED24 PRAMEF14 MED7

2.87e-051081136GO:0035019
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

TRPM4 CACNA2D1 UTS2R CALCA FFAR1 ACKR4 BDKRB1 RIC3

3.29e-052241138GO:0007204
GeneOntologyBiologicalProcesstransmission of nerve impulse

FFAR3 GPR42 SCN1A SCN2A SCN3A JAM3

3.53e-051121136GO:0019226
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TRPM4 ANO9 CACNA2D1 SLC36A1 ABCB7 CALCA FFAR1 BDKRB1 SLC36A2 SLC3A2 KCNG2 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

3.81e-05101711317GO:0098660
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

TRPM4 CACNA2D1 SLC36A1 ABCB7 CALCA FFAR1 BDKRB1 SLC36A2 SLC3A2 KCNG2 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

4.23e-0592211316GO:0098662
GeneOntologyBiologicalProcessproline transport

SLC36A1 SLC36A2 SLC3A2

4.40e-05131133GO:0015824
GeneOntologyBiologicalProcessnegative regulation of peptide hormone secretion

FFAR3 GPR42 FFAR2 HMGCR ABCC8

5.04e-05731135GO:0090278
GeneOntologyBiologicalProcessnegative regulation of peptide secretion

FFAR3 GPR42 FFAR2 HMGCR ABCC8

5.74e-05751135GO:0002792
GeneOntologyBiologicalProcessblastocyst formation

PRAMEF1 PRAMEF2 PRAMEF13 MFNG PRAMEF14

6.93e-05781135GO:0001825
GeneOntologyBiologicalProcessmembrane depolarization during bundle of His cell action potential

TRPM4 CACNA2D1

8.89e-0531132GO:0086048
GeneOntologyBiologicalProcesscardiac muscle cell action potential

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

1.17e-04871135GO:0086001
GeneOntologyBiologicalProcessvascular process in circulatory system

MKKS TRPM4 UTS2R CALCA HMGCR BCR SLC1A5 ATP8A1 ABCC8

1.17e-043441139GO:0003018
GeneOntologyBiologicalProcesspositive regulation of action potential

TRPM4 FFAR3 GPR42

1.23e-04181133GO:0045760
GeneOntologyBiologicalProcessalanine transport

SLC36A1 SLC36A2 SLC3A2

1.23e-04181133GO:0032328
GeneOntologyBiologicalProcesshormone transport

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 SLC3A2 ABCC8 HTT

1.33e-0443211310GO:0009914
GeneOntologyBiologicalProcessinsulin secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 HTT

1.34e-042741138GO:0030073
GeneOntologyBiologicalProcessorganic cation transport

SLC36A1 FFAR3 GPR42 SLC1A5 SLC36A2 SLC3A2

1.48e-041451136GO:0015695
GeneOntologyBiologicalProcesscardiac muscle cell contraction

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

1.60e-04931135GO:0086003
GeneOntologyBiologicalProcessoocyte development

PRAMEF1 PRAMEF2 PRAMEF13 WASHC5 PRAMEF14

2.14e-04991135GO:0048599
GeneOntologyBiologicalProcessheart contraction

TRPM4 CACNA2D1 FFAR3 GPR42 KCNG2 SCN1A SCN2A SCN3A

2.38e-042981138GO:0060047
GeneOntologyBiologicalProcessnegative regulation of protein secretion

FFAR3 GPR42 FFAR2 HMGCR ABCC8

2.58e-041031135GO:0050709
GeneOntologyBiologicalProcessoocyte differentiation

PRAMEF1 PRAMEF2 PRAMEF13 WASHC5 PRAMEF14

2.58e-041031135GO:0009994
GeneOntologyBiologicalProcessnegative regulation of hormone secretion

FFAR3 GPR42 FFAR2 HMGCR ABCC8

2.58e-041031135GO:0046888
GeneOntologyBiologicalProcessimport across plasma membrane

TRPM4 CACNA2D1 SLC36A1 SLC1A5 SLC36A2 SLC3A2 ABCC8

2.78e-042301137GO:0098739
GeneOntologyBiologicalProcessregulation of insulin secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8

2.85e-042311137GO:0050796
GeneOntologyBiologicalProcessamino acid import across plasma membrane

SLC36A1 SLC1A5 SLC36A2 SLC3A2

2.88e-04581134GO:0089718
GeneOntologyBiologicalProcessheart process

TRPM4 CACNA2D1 FFAR3 GPR42 KCNG2 SCN1A SCN2A SCN3A

3.04e-043091138GO:0003015
GeneOntologyBiologicalProcessL-amino acid transport

SLC36A1 SLC1A5 SLC36A2 SLC3A2 ABCC8

3.21e-041081135GO:0015807
GeneOntologyBiologicalProcessneutral amino acid transport

SLC36A1 SLC1A5 SLC36A2 SLC3A2

3.29e-04601134GO:0015804
GeneOntologyBiologicalProcessstem cell population maintenance

PRAMEF1 PRAMEF2 PRAMEF13 FANCD2 MED24 PRAMEF14 MED7

3.33e-042371137GO:0019827
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D5 RALGAPB BCR ARHGEF15 TBC1D17

3.35e-041091135GO:0090630
GeneOntologyBiologicalProcessmetal ion transport

TRPM4 CACNA2D1 ABCB7 CALCA FFAR1 SLC10A4 BDKRB1 SLC3A2 KCNG2 ABCC8 SCN1A SCN2A SCN3A TMCO3 HTT

3.66e-04100011315GO:0030001
GeneOntologyBiologicalProcessregulation of hormone levels

TRPM4 FFAR1 CYP3A43 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 SLC3A2 TG ABCC8 HTT

3.73e-0468411312GO:0010817
GeneOntologyBiologicalProcessmaintenance of cell number

PRAMEF1 PRAMEF2 PRAMEF13 FANCD2 MED24 PRAMEF14 MED7

3.77e-042421137GO:0098727
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC36A1 SLC10A4 ABCC11 SLC1A5 SLC36A2 SLC3A2 ABCC8 SLC16A14 PLA2G4F

4.29e-044101139GO:0046942
GeneOntologyBiologicalProcesspositive regulation of neuronal action potential

FFAR3 GPR42

4.40e-0461132GO:1904457
GeneOntologyBiologicalProcessorganic acid transport

SLC36A1 SLC10A4 ABCC11 SLC1A5 SLC36A2 SLC3A2 ABCC8 SLC16A14 PLA2G4F

4.44e-044121139GO:0015849
GeneOntologyBiologicalProcesspeptide hormone secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 HTT

5.10e-043341138GO:0030072
GeneOntologyBiologicalProcesshormone secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 ABCC8 HTT

5.10e-044201139GO:0046879
GeneOntologyBiologicalProcessmembrane depolarization

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

5.42e-041211135GO:0051899
GeneOntologyBiologicalProcessexport from cell

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 NR4A1 BCR SLC1A5 SLC36A2 WASHC5 ABCC8 VPS35 MRGPRX4 HTT

5.43e-04115311316GO:0140352
GeneOntologyBiologicalProcessglucose homeostasis

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HECTD4 HMGCR ABCC8

5.51e-043381138GO:0042593
GeneOntologyBiologicalProcessresponse to fatty acid

FFAR1 FFAR3 GPR42 FFAR2

5.61e-04691134GO:0070542
GeneOntologyBiologicalProcesscarbohydrate homeostasis

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HECTD4 HMGCR ABCC8

5.62e-043391138GO:0033500
GeneOntologyBiologicalProcesspeptide secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 HTT

6.07e-043431138GO:0002790
GeneOntologyBiologicalProcessbundle of His cell action potential

TRPM4 CACNA2D1

6.14e-0471132GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

TRPM4 CACNA2D1

6.14e-0471132GO:0086028
GeneOntologyBiologicalProcessactin-mediated cell contraction

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

6.75e-041271135GO:0070252
GeneOntologyBiologicalProcessregulation of protein secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 VPS35

6.92e-043501138GO:0050708
GeneOntologyBiologicalProcesssecretion by cell

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 NR4A1 BCR SLC1A5 WASHC5 ABCC8 VPS35 MRGPRX4 HTT

6.98e-04106411315GO:0032940
GeneOntologyBiologicalProcesspeptide transport

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 HTT

7.59e-043551138GO:0015833
GeneOntologyBiologicalProcessimport into cell

TRPM4 CACNA2D1 SLC36A1 CALCA TBC1D5 COLEC10 BCR SLC1A5 SLC36A2 SLC3A2 STAB1 ATP8A1 WASHC5 ABCC8 SRPX

7.68e-04107411315GO:0098657
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

GPR18 GPR20 CALCA FFAR1 FFAR2

8.31e-041331135GO:0007200
GeneOntologyBiologicalProcessregulation of peptide hormone secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8

8.40e-042771137GO:0090276
GeneOntologyBiologicalProcessnon-motile cilium assembly

MKKS TMEM67 TMEM17 HTT

8.92e-04781134GO:1905515
GeneOntologyBiologicalProcessvisual learning

HMGCR ABCC8 RIC8A HTT

8.92e-04781134GO:0008542
GeneOntologyBiologicalProcesssignal release

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 NR4A1 ABCC8 VPS35 HTT

9.20e-0465311311GO:0023061
GeneOntologyBiologicalProcessregulation of peptide transport

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8

9.33e-042821137GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8

9.33e-042821137GO:0002791
GeneOntologyBiologicalProcesssecretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR NIBAN2 NR4A1 BCR SLC1A5 WASHC5 ABCC8 VPS35 MRGPRX4 PLA2G4F HTT

1.00e-03122111316GO:0046903
GeneOntologyBiologicalProcessregulation of action potential

TRPM4 CACNA2D1 FFAR3 GPR42

1.03e-03811134GO:0098900
GeneOntologyBiologicalProcessprotein localization to perinuclear region of cytoplasm

FHIP1B FHIP1A

1.04e-0391132GO:1905719
GeneOntologyBiologicalProcessregulation of heart rate by chemical signal

FFAR3 GPR42

1.04e-0391132GO:0003062
GeneOntologyBiologicalProcessnegative regulation of secretion by cell

FFAR3 GPR42 FFAR2 HMGCR BCR ABCC8

1.17e-032141136GO:1903531
GeneOntologyBiologicalProcesscilium organization

MKKS TMEM67 CATIP TMEM17 TBC1D5 TBC1D17 WDR11 DNAH8 HTT

1.23e-034761139GO:0044782
GeneOntologyBiologicalProcessstriated muscle contraction

TRPM4 CACNA2D1 NR4A1 SCN1A SCN2A SCN3A

1.26e-032171136GO:0006941
GeneOntologyBiologicalProcessvisual behavior

HMGCR ABCC8 RIC8A HTT

1.28e-03861134GO:0007632
GeneOntologyBiologicalProcessprotein secretion

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 VPS35 HTT

1.31e-034801139GO:0009306
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC36A1 SLC1A5 SLC36A2 SLC3A2

1.34e-03871134GO:1902475
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 VPS35 HTT

1.37e-034831139GO:0035592
GeneOntologyBiologicalProcessprotein localization to extracellular region

TRPM4 FFAR1 FFAR3 GPR42 FFAR2 HMGCR ABCC8 VPS35 HTT

1.51e-034901139GO:0071692
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

NPBWR1 UTS2R GPR18 GPR20 CALCA FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1 OR8G2P TAS2R5 VPS35 MRGPRX4 RIC8A HTT

1.53e-03139511317GO:0007186
GeneOntologyBiologicalProcessnegative regulation of protein transport

FFAR3 GPR42 FFAR2 HMGCR ABCC8

1.55e-031531135GO:0051224
GeneOntologyBiologicalProcessactin filament-based movement

TRPM4 CACNA2D1 SCN1A SCN2A SCN3A

1.55e-031531135GO:0030048
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response

FFAR3 GPR42 FFAR2

1.57e-03421133GO:0002675
GeneOntologyBiologicalProcesscellular response to fatty acid

FFAR3 GPR42 FFAR2

1.57e-03421133GO:0071398
GeneOntologyBiologicalProcessmaintenance of blood-brain barrier

ESAM ABCC8 JAM3

1.57e-03421133GO:0035633
GeneOntologyBiologicalProcesscalcium ion transport into cytosol

CACNA2D1 CALCA FFAR1

1.57e-03421133GO:0060402
GeneOntologyBiologicalProcessproline transmembrane transport

SLC36A1 SLC36A2

1.58e-03111132GO:0035524
GeneOntologyBiologicalProcessmuscle contraction

MKKS TRPM4 CACNA2D1 CALCA NR4A1 SCN1A SCN2A SCN3A

1.63e-034001138GO:0006936
GeneOntologyBiologicalProcessoogenesis

PRAMEF1 PRAMEF2 PRAMEF13 WASHC5 PRAMEF14

1.69e-031561135GO:0048477
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHGB5 ESAM COLEC10 NECTIN3 LRRC4C PCDHGB4 RIC8A

1.70e-033131137GO:0098742
GeneOntologyBiologicalProcessregulation of postsynapse assembly

NECTIN3 ARHGEF15 VPS35

1.80e-03441133GO:0150052
GeneOntologyCellularComponentsodium channel complex

TRPM4 SCN1A SCN2A SCN3A

1.79e-05291144GO:0034706
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A

1.02e-04171143GO:0001518
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.25e-04471144GO:0031462
GeneOntologyCellularComponentcation channel complex

TRPM4 CACNA2D1 KCNG2 ABCC8 SCN1A SCN2A SCN3A

3.08e-042351147GO:0034703
GeneOntologyCellularComponentautophagosome

ATG9B TBC1D5 TBC1D17 SRPX HTT

4.92e-041191145GO:0005776
DomainGPR40-rel_orph

FFAR1 FFAR3 GPR42 FFAR2

1.23e-0941124IPR013312
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

4.14e-0661123PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

4.14e-0661123IPR024583
DomainABC_transporter_CS

ABCB7 ABCF3 ABCC11 ABCC8 ABCG8

5.05e-06421125IPR017871
DomainABC_tran

ABCB7 ABCF3 ABCC11 ABCC8 ABCG8

9.88e-06481125PF00005
DomainABC_TRANSPORTER_2

ABCB7 ABCF3 ABCC11 ABCC8 ABCG8

9.88e-06481125PS50893
DomainABC_TRANSPORTER_1

ABCB7 ABCF3 ABCC11 ABCC8 ABCG8

1.10e-05491125PS00211
DomainABC_transporter-like

ABCB7 ABCF3 ABCC11 ABCC8 ABCG8

1.21e-05501125IPR003439
DomainNa_channel_asu

SCN1A SCN2A SCN3A

2.44e-05101123IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A

2.44e-05101123IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A

2.44e-05101123PF06512
DomainGPR40_recept_FA

FFAR1 FFAR2

3.56e-0521122IPR013313
DomainPRAME_family

PRAMEF1 PRAMEF2 PRAMEF13

1.90e-04191123IPR026271
DomainKASH

SYNE4 SYNE3

2.12e-0441122PF10541
DomainKASH

SYNE4 SYNE3

2.12e-0441122IPR012315
DomainRetinoicA-induced_16-like

FHIP1B FHIP1A

2.12e-0441122IPR019384
DomainRAI16-like

FHIP1B FHIP1A

2.12e-0441122PF10257
DomainKASH

SYNE4 SYNE3

2.12e-0441122PS51049
DomainKASH

SYNE4 SYNE3

2.12e-0441122SM01249
DomainAAA+_ATPase

ABCB7 ABCF3 ABCC11 MCM4 ABCC8 DNAH8

2.31e-041441126IPR003593
DomainAAA

ABCB7 ABCF3 ABCC11 MCM4 ABCC8 DNAH8

2.31e-041441126SM00382
DomainChannel_four-helix_dom

KCNG2 SCN1A SCN2A SCN3A

3.79e-04571124IPR027359
Domain-

KCNG2 SCN1A SCN2A SCN3A

3.79e-045711241.20.120.350
DomainABC_membrane

ABCB7 ABCC11 ABCC8

3.88e-04241123PF00664
DomainABC_TM1F

ABCB7 ABCC11 ABCC8

6.17e-04281123PS50929
DomainABC1_TM_dom

ABCB7 ABCC11 ABCC8

6.17e-04281123IPR011527
DomainIon_trans_dom

TRPM4 KCNG2 SCN1A SCN2A SCN3A

6.19e-041141125IPR005821
DomainIon_trans

TRPM4 KCNG2 SCN1A SCN2A SCN3A

6.19e-041141125PF00520
Domain7tm_1

NPBWR1 UTS2R GPR18 GPR20 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1 OR8G2P MRGPRX4

7.53e-0467711212PF00001
DomainG_PROTEIN_RECEP_F1_1

NPBWR1 UTS2R GPR18 GPR20 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1 OR8G2P MRGPRX4

8.34e-0468511212PS00237
DomainG_PROTEIN_RECEP_F1_2

NPBWR1 UTS2R GPR18 GPR20 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1 OR8G2P MRGPRX4

8.99e-0469111212PS50262
DomainGPCR_Rhodpsn

NPBWR1 UTS2R GPR18 GPR20 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1 OR8G2P MRGPRX4

9.11e-0469211212IPR000276
DomainHis_Pase_clade-2

MINPP1 PXYLP1

9.75e-0481122IPR000560
DomainHis_Phos_2

MINPP1 PXYLP1

9.75e-0481122PF00328
DomainGPCR_Rhodpsn_7TM

NPBWR1 UTS2R GPR18 GPR20 FFAR1 FFAR3 FFAR2 ACKR4 BDKRB1 OR8G2P MRGPRX4

2.30e-0367011211IPR017452
DomainAa_trans

SLC36A1 SLC36A2

4.57e-03171122PF01490
DomainAA_transpt_TM

SLC36A1 SLC36A2

4.57e-03171122IPR013057
PathwayREACTOME_FREE_FATTY_ACID_RECEPTORS

FFAR1 FFAR3 FFAR2

2.02e-065843M27368
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

NPBWR1 GPR18 GPR20 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1

2.37e-05260849M39397
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC36A1 SLC1A5 SLC36A2 SLC3A2

3.71e-0532844MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC36A1 SLC1A5 SLC36A2 SLC3A2

4.21e-0533844M188
PathwayREACTOME_SIGNALING_BY_GPCR

NPBWR1 UTS2R GPR18 GPR20 CALCA FFAR1 FFAR3 GPR42 FFAR2 ARHGEF38 ACKR4 BDKRB1 ARHGEF15

1.08e-046468413MM14962
PathwayKEGG_ABC_TRANSPORTERS

ABCB7 ABCC11 ABCC8 ABCG8

1.33e-0444844M11911
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

NPBWR1 UTS2R GPR18 FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1

1.59e-04333849MM14963
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TRPM4 TAS2R5 SCN2A SCN3A

1.72e-0447844M42524
PathwayWP_GPCRS_NONODORANT

NPBWR1 UTS2R GPR18 FFAR1 FFAR3 GPR42 FFAR2 BDKRB1

1.83e-04266848MM15843
PathwayREACTOME_GPCR_LIGAND_BINDING

NPBWR1 UTS2R GPR18 CALCA FFAR1 FFAR3 GPR42 FFAR2 ACKR4 BDKRB1

2.31e-044308410MM15160
PathwayREACTOME_SIGNALING_BY_GPCR

NPBWR1 UTS2R GPR18 GPR20 CALCA FFAR1 FFAR3 FFAR2 ARHGEF38 ACKR4 BDKRB1 ARHGEF15 TAS2R5

2.46e-047028413M746
PathwayREACTOME_GPCR_LIGAND_BINDING

NPBWR1 UTS2R GPR18 CALCA FFAR1 FFAR3 FFAR2 ACKR4 BDKRB1 TAS2R5

4.16e-044638410M507
PathwayWP_SCFA_AND_SKELETAL_MUSCLE_SUBSTRATE_METABOLISM

FFAR3 FFAR2

5.18e-046842M39453
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A

6.00e-0428843M45519
PathwayWP_MRNA_PROTEIN_AND_METABOLITE_INDUCATION_PATHWAY_BY_CYCLOSPORIN_A

SLC1A5 SLC3A2

7.23e-047842M42540
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

NPBWR1 UTS2R GPR18 FFAR1 FFAR3 FFAR2 ACKR4 BDKRB1

7.70e-04330848M18334
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN3A

8.13e-0431843M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN3A

8.94e-0432843M27455
Pubmed

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.

FFAR1 FFAR3 GPR42 FFAR2

1.09e-10411449344866
Pubmed

A family of fatty acid binding receptors.

FFAR1 FFAR3 GPR42 FFAR2

1.09e-104114415684720
Pubmed

Fatty acid binding receptors and their physiological role in type 2 diabetes.

FFAR1 FFAR3 GPR42 FFAR2

5.46e-105114419009545
Pubmed

Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis.

FFAR1 FFAR3 GPR42 FFAR2

1.63e-096114419460454
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

3.43e-083114312610651
Pubmed

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

FFAR3 GPR42 FFAR2

3.43e-083114312496283
Pubmed

Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.

FFAR3 GPR42 FFAR2

3.43e-083114323665276
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

3.43e-083114323859570
Pubmed

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.

FFAR3 GPR42 FFAR2

3.43e-083114334210970
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

3.43e-083114318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

3.43e-083114317544618
Pubmed

Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3.

FFAR3 GPR42 FFAR2

3.43e-083114331719611
Pubmed

Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43.

FFAR3 GPR42 FFAR2

3.43e-083114316123168
Pubmed

GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 and GPR41 proteins.

FFAR1 FFAR3 GPR42

3.43e-083114322493486
Pubmed

Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.

FFAR3 GPR42 FFAR2

3.43e-083114323066016
Pubmed

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.

FFAR3 GPR42 FFAR2

3.43e-083114325581519
Pubmed

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.

FFAR3 GPR42 FFAR2

3.43e-083114322190648
Pubmed

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.

FFAR3 GPR42 FFAR2

3.43e-083114331272808
Pubmed

GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes.

FFAR3 GPR42 FFAR2

3.43e-083114323885020
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

3.43e-083114314973256
Pubmed

Dietary Fiber Confers Protection against Flu by Shaping Ly6c- Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism.

FFAR3 GPR42 FFAR2

3.43e-083114329768180
Pubmed

GPR41 and GPR43 regulate CD8+ T cell priming during herpes simplex virus type 1 infection.

FFAR3 GPR42 FFAR2

3.43e-083114338524121
Pubmed

Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function.

FFAR3 GPR42 FFAR2

3.43e-083114338329121
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PIGN USP34 TMEM67 CACNA2D1 COL7A1 NAT14 ABCB7 ERP44 HMGCR NECTIN3 MINPP1 SLC3A2 VPS35 LTN1 LTBR TMEM164 TMCO3 HTT

7.51e-0812011141835696571
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A

1.37e-074114317537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A

1.37e-074114335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A

1.37e-074114329578003
Pubmed

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41).

FFAR3 GPR42 FFAR2

1.37e-074114321518883
Pubmed

Free Fatty Acid Receptors in Health and Disease.

FFAR1 FFAR3 FFAR2

1.37e-074114331487233
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

1.37e-074114335801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

1.37e-07411438974318
Pubmed

Microbial metabolites, short-chain fatty acids, restrain tissue bacterial load, chronic inflammation, and associated cancer in the colon of mice.

FFAR3 GPR42 FFAR2

1.37e-074114329644622
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.23e-0718114423894331
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.23e-0718114412890732
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.23e-0718114429731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.23e-0718114414675769
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

3.41e-07511431679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A

3.41e-07511438812438
Pubmed

Receptor-specific regulation of ERK1/2 activation by members of the "free fatty acid receptor" family.

FFAR1 FFAR3 FFAR2

3.41e-075114322712802
Pubmed

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.

FFAR3 GPR42 FFAR2

3.41e-075114324327954
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

3.41e-075114324337656
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

4.09e-0719114428604677
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

5.09e-0720114426694250
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

5.09e-0720114416580637
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

5.09e-0720114421425410
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A

6.81e-076114323652591
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

7.65e-0722114431729367
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

9.24e-0723114419480014
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.31e-0625114437451217
Pubmed

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.31e-0625114412620990
Pubmed

Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.55e-0626114418500982
Pubmed

Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.

FFAR3 GPR42 FFAR2

1.90e-068114334626852
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.11e-0628114425089626
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.81e-0630114438786026
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A

2.84e-069114316382098
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A

2.84e-069114315746173
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC36A1 SLC1A5 SLC36A2 SLC3A2

3.22e-0631114418195088
Pubmed

LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.67e-0632114437889087
Pubmed

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.

TBC1D5 WASHC5 VPS35

4.05e-0610114320923837
Pubmed

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.

NECTIN3 SLC1A5 SLC3A2 RIC8A SEMA4A JAM3

5.08e-06132114626439863
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

5.30e-0635114419389355
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

7.38e-061211438169823
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A

7.38e-0612114330175250
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A

9.58e-0613114315123669
Pubmed

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.

FFAR3 GPR42

1.07e-052114225637492
Pubmed

Variants in genes encoding the SUR1-TRPM4 non-selective cation channel and sudden infant death syndrome (SIDS): potentially increased risk for cerebral edema.

TRPM4 ABCC8

1.07e-052114235474489
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

1.07e-052114229649454
Pubmed

Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters.

SLC36A1 SLC36A2

1.07e-052114211959859
Pubmed

Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.

FFAR3 GPR42

1.07e-052114230478340
Pubmed

3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.

FFAR3 GPR42

1.07e-052114238040866
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

1.07e-052114220346423
Pubmed

Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.

FFAR3 GPR42

1.07e-052114235408893
Pubmed

FFAR3 modulates insulin secretion and global gene expression in mouse islets.

FFAR3 GPR42

1.07e-052114226091414
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

1.07e-052114210827969
Pubmed

GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.

FFAR3 GPR42

1.07e-052114227550964
Pubmed

Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.

FFAR3 GPR42

1.07e-052114235858247
Pubmed

Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids.

FFAR3 FFAR2

1.07e-052114218801738
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

1.07e-052114219694741
Pubmed

Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury.

TRPM4 ABCC8

1.07e-052114230484364
Pubmed

The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.

TRPM4 ABCC8

1.07e-052114227246103
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

1.07e-052114211245985
Pubmed

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

FFAR3 GPR42

1.07e-052114222506074
Pubmed

Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.

FFAR3 GPR42

1.07e-052114232073900
Pubmed

Short-chain fatty acids, GPR41 and GPR43 ligands, inhibit TNF-α-induced MCP-1 expression by modulating p38 and JNK signaling pathways in human renal cortical epithelial cells.

FFAR3 FFAR2

1.07e-052114228322790
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

1.07e-05211421317301
Pubmed

The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.

FFAR3 GPR42

1.07e-052114224748202
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

1.07e-052114223016767
Pubmed

The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.

FFAR3 GPR42

1.07e-052114236362376
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

1.07e-052114227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

1.07e-052114233096315
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

1.07e-052114224990319
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

1.07e-052114231439038
Pubmed

Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma.

FFAR3 FFAR2

1.07e-052114228075383
Pubmed

Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line.

FFAR3 FFAR2

1.07e-052114216887331
Pubmed

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.

FFAR3 GPR42

1.07e-052114220399779
Pubmed

Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.

TRPM4 ABCC8

1.07e-052114234309670
Pubmed

Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.

FFAR3 GPR42

1.07e-052114219630535
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

1.07e-052114226311622
Pubmed

Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.

TRPM4 ABCC8

1.07e-052114226172285
Pubmed

International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions.

FFAR1 FFAR2

1.07e-052114219047536
Cytoband19q13.1

FFAR1 FFAR3 GPR42 FFAR2

1.12e-0555114419q13.1
Cytoband1p36.21

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.92e-056311441p36.21
CytobandEnsembl 112 genes in cytogenetic band chr19q13

TRPM4 NAT14 FFAR1 FFAR3 GPR42 FFAR2 HIF3A SYNE4 SLC1A5 TBC1D17 MAP4K1

1.94e-04119211411chr19q13
Cytoband15q15.1

EXD1 RPAP1 PLA2G4F

2.23e-0447114315q15.1
CytobandEnsembl 112 genes in cytogenetic band chr11p15

ANO9 CALCA FHIP1B ABCC8 MRGPRX4 RIC8A RIC3

5.40e-045641147chr11p15
Cytoband2q24.3

SCN1A SCN2A

7.17e-041611422q24.3
Cytoband5q33.1

SLC36A1 SLC36A2

1.91e-032611425q33.1
Cytoband2p15

USP34 TMEM17

2.71e-033111422p15
Cytoband4q31.3

PRSS48 FHIP1A

2.71e-033111424q31.3
CytobandEnsembl 112 genes in cytogenetic band chr5q33

SLC36A1 SLC36A2 MED7

3.23e-031181143chr5q33
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A

3.98e-031271143chr2q24
Cytoband3p21.1

COL7A1 STAB1

4.93e-034211423p21.1
CytobandEnsembl 112 genes in cytogenetic band chr2p15

USP34 TMEM17

5.40e-03441142chr2p15
GeneFamilyFree fatty acid receptors

FFAR1 FFAR3 FFAR2

5.08e-074923203
GeneFamilyPRAME family

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

6.17e-0624924686
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A

1.05e-0599231203
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE4 SYNE3

1.53e-0449221252
GeneFamilyG protein-coupled receptors, Class A orphans

GPR18 GPR20 GPR42 MRGPRX4

6.72e-0478924262
GeneFamilyATP binding cassette subfamily C

ABCC11 ABCC8

1.93e-0313922807
CoexpressionKINNEY_DNMT1_METHYLATION_TARGETS

FFAR3 GPR42 PRAMEF1 PRAMEF2 PRAMEF13

3.58e-07341145MM955
CoexpressionMIKKELSEN_ES_ICP_WITH_H3K4ME3

TNK1 TMEM67 COL7A1 NAT14 PRAMEF1 PRAMEF2 PRAMEF13 ARHGEF15 MED24 MFNG PRAMEF14 SCN1A STOML1 ZC3H12D

1.11e-0580711414MM855
CoexpressionKOHOUTEK_CCNT2_TARGETS

CALCA PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.81e-05811145MM938
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 HIF3A LRRC4C ATP8A1 SCN1A PLA2G4F TMEM164 FHIP1A

2.90e-0818711485df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellBac-SEP-Lymphocyte-B-B_intermediate|Bac-SEP / Disease, Lineage and Cell Type

GPR18 ESAM SCN2A DNAH8 JAM3 RIC3

3.71e-061611146bcd122af09cbb99d1816200d9c367af8b7f36873
ToppCellcontrol-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GPR18 SYNE3 MAP4K1 SCN3A ZC3H12D DNAH8

7.26e-061811146e414303bb90e5fe7b667c2acf9a50f8694b90e54
ToppCellNS-control-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GPR18 SYNE3 MAP4K1 SCN3A ZC3H12D DNAH8

7.49e-0618211464b9b55154a79992112c1c467e8752c3cdbb541d9
ToppCelldroplet-Bladder-nan-24m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR20 PCDHGB5 ESAM ACKR4 STAB1 MFNG

8.22e-06185114690caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FHIP1B INTS5 SYNE3 WDR11 LTN1 TMEM164

8.48e-061861146927723ad579bbd9947ff525bd501e222d3fa9289
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

ESAM HIF3A NR4A1 ARHGEF15 ABCC8 JAM3

8.74e-061871146f3548817f2fded5978137bb252cb628ac199e4f6
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESAM NECTIN3 ACKR4 ARHGEF15 STAB1 MFNG

9.01e-061881146db0652f000d459493321b53239326706eace598c
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NECTIN3 ACKR4 STAB1 MFNG ATP8A1 VPS35

9.29e-06189114609dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM NECTIN3 ACKR4 ARHGEF15 STAB1 MFNG

9.29e-0618911467b6cb745c0a637d6addc105a79059ed488fced39
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

CACNA2D1 CALCA FFAR2 ARHGEF15 MFNG SCN3A

9.29e-0618911466baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

ATP8A1 MAP4K1 SCN3A ZC3H12D DNAH8 RIC3

9.57e-061901146374d8fd63c733178acab07682ed1519693efab45
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164 FHIP1A

9.86e-061911146a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

CACNA2D1 CALCA ABCC8 SCN2A SCN3A RIC3

9.86e-06191114676311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164 FHIP1A

1.02e-05192114658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 LRRC4C ATP8A1 SCN1A PLA2G4F FHIP1A

1.02e-051921146cc9911e182a289779a2612bc213daae5607689e7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 LRRC4C ATP8A1 PLA2G4F TMEM164 FHIP1A

1.02e-051921146fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellNeuroendocrine|World / Class top

CACNA2D1 CALCA FFAR2 ARHGEF15 MFNG SCN3A

1.02e-0519211460199da3ef9ddb6673e9aa41f346f374838aec182
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164 FHIP1A

1.05e-051931146fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164 FHIP1A

1.05e-051931146f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 ATP8A1 ABCC8 SCN3A FHIP1A RIC3

1.08e-051941146b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellSepsis-Bac-SEP-Lymphocyte-B-B_intermediate|Bac-SEP / Disease, condition lineage and cell class

GPR18 ESAM SCN2A DNAH8 JAM3 RIC3

1.14e-0519611461611920211beb1a3691e3853e0314792a74279a0
ToppCellInfluenza-Influenza_Severe-Lymphocyte-B-B_intermediate|Influenza_Severe / Disease, condition lineage and cell class

GPR18 MAP4K1 ZC3H12D DNAH8 JAM3 RIC3

1.21e-051981146ab622fee61714471af3a7be0af356e8a484dcaff
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164 FHIP1A

1.21e-051981146f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HMGCR HIF3A LRRC4C ABCC8 SCN1A SCN2A

1.25e-05199114619a97e27a4758e794ce7246d295e112b47931a48
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF38 HMGCR ATP8A1 SCN1A PLA2G4F TMEM164

1.25e-0519911462dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ESAM HIF3A ARHGEF15 ABCC8 SRPX JAM3

1.28e-052001146ec9a18576a3d08ddfceb70d114c4ab861fbb0d08
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FFAR3 BDKRB1 MAP4K1 SPOCD1

4.14e-057511449a82db6281326acc534b800e02b262a8617a147e
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FFAR3 BDKRB1 MAP4K1 SPOCD1

4.14e-057511447678e7d514560c774b56fc0a20312d561c89f587
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FFAR3 BDKRB1 MAP4K1 SPOCD1

4.14e-057511447f1fc575fca42352434f7188c7a95b50372aeefa
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM BCR STAB1 MFNG SCN3A

4.22e-05150114596b160f163030fbf48aedc37d6ae224e11492c52
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

HIF3A ARHGEF15 ABCC8 SRPX JAM3

5.74e-0516011450cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR18 NR4A1 SLC1A5 MAP4K1 SEMA4A

5.74e-0516011451f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP INTS5 SCN2A RASGEF1C SRPX

6.27e-051631145360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP INTS5 SCN2A RASGEF1C SRPX

6.27e-051631145b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BCR STAB1 KCNG2 SCN1A SCN3A

6.45e-0516411454cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BCR STAB1 KCNG2 SCN1A SCN3A

6.45e-0516411457a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BCR STAB1 KCNG2 SCN1A SCN3A

6.45e-0516411455e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BCR STAB1 KCNG2 SCN1A SCN3A

6.45e-051641145f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC10A4 BCR STAB1 SCN1A SCN3A

6.64e-051651145347b59aa625a8a960828b8620824d8ac48990e07
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR18 SLC10A4 TG MAP4K1 ZC3H12D

6.64e-05165114536415924d05373e9dd3665be599f4f3f40bf0497
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC10A4 BCR STAB1 SCN1A SCN3A

6.64e-051651145507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC10A4 BCR STAB1 SCN1A SCN3A

6.64e-05165114539a25be081a5d59c7cf107a997d352793d5025fb
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR18 SLC10A4 TG MAP4K1 ZC3H12D

6.64e-05165114556310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC10A4 BCR STAB1 SCN1A SCN3A

6.64e-0516511451890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

ESAM ABCC8 SRPX PRSS48 JAM3

7.43e-051691145e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATG9B MFNG MAP4K1 ABCC8 ZC3H12D

8.08e-051721145425970e9ce8943f7e2ba6ca958e7a3a29baa798c
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATG9B MFNG MAP4K1 ABCC8 ZC3H12D

8.08e-051721145ca0cc0e92b6cdce5016f18fcb2ec1508cb222502
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA2D1 FFAR2 NR4A1 SCN2A SCN3A

8.53e-051741145a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCelldroplet-Liver-LIVER-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM ACKR4 ARHGEF15 DNAH8 JAM3

9.00e-0517611454d2fb51e71bed0d72f3d7f89d395744860885a5f
ToppCelldroplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM ACKR4 ARHGEF15 DNAH8 JAM3

9.00e-0517611454880fa20b50eb10358e08567e08559ef2954f237
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA2D1 FFAR1 ABCC8 SCN2A SCN3A

9.00e-0517611452e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TNK1 CACNA2D1 PAMR1 BDKRB1 SRPX

9.00e-051761145bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCelldroplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM ACKR4 ARHGEF15 DNAH8 JAM3

9.00e-051761145fcdddd949ca05b3ecde240db9e38296a6eab2d6a
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TNK1 CACNA2D1 PAMR1 BDKRB1 SRPX

9.24e-0517711453d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellNS-critical-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GPR18 MAP4K1 SCN3A ZC3H12D DNAH8

9.24e-051771145d4db058c09012ec9fbde61277a9f86d9956de8fc
ToppCellNS-moderate-d_16-33-Lymphoid-B_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GPR18 NR4A1 SCN3A ZC3H12D DNAH8

9.24e-051771145320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COLEC10 LRRC4C RASGEF1C SEMA4A ABCG8

9.49e-051781145c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell15-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

CALCA FFAR2 ABCC8 SCN3A RIC3

9.75e-051791145bc04789f0fbd293fdcea66acba8cf227af251b7a
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164

1.00e-041801145198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALCA LRRC4C NR4A1 BDKRB1 SRPX

1.03e-041811145ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

PAMR1 SLC36A2 ABCC8 SRPX PLA2G4F

1.05e-041821145354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATG9B SLC10A4 PANX2 ABCC8 SCN1A

1.05e-04182114504ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CALCA SYNE4 SCN3A PLA2G4F RIC3

1.05e-041821145dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA2D1 NAT14 FFAR1 HIF3A ABCC8

1.08e-04183114549f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

NAT14 GPR20 ESAM LRRC4C BCR

1.11e-04184114583987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellfacs-Pancreas-Endocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM NR4A1 ACKR4 ARHGEF15 MFNG

1.14e-0418511457f9121bbff3471982aa8706a599922c2d28e6e9b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 PAMR1 COLEC10 LRRC4C JAM3

1.14e-041851145f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 BCR STAB1 ATP8A1 SCN3A

1.14e-041851145bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 BCR STAB1 WASHC5 SCN2A

1.14e-0418511451b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCellfacs-Pancreas-Endocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM NR4A1 ACKR4 ARHGEF15 MFNG

1.14e-0418511458159e0aef2c8826e0deac6fdc90505ac0400ba2b
ToppCellfacs-Pancreas-Endocrine-24m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM NR4A1 ACKR4 ARHGEF15 MFNG

1.14e-0418511458626fb015cfa20c847661b74ef51ca0dfd1025e0
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 BCR STAB1 WASHC5 SCN2A

1.14e-04185114502cbf492bc40abebaa93a3a208888afae72fbe06
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 PAMR1 COLEC10 LRRC4C JAM3

1.14e-04185114540e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 PAMR1 COLEC10 LRRC4C JAM3

1.14e-0418511455f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

HIF3A BCR ARHGEF15 SRPX JAM3

1.14e-041851145dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCB7 PAMR1 ESAM MED24 DNAH8

1.17e-04186114539e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM NECTIN3 ACKR4 MFNG ATP8A1

1.17e-0418611459d6cb36aa0aae69fe584dad31deafcfdcc9fd1db
ToppCellBL-critical-LOC-Lymphoid-B_cell|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GPR18 LRRC4C SCN3A DNAH8 JAM3

1.17e-04186114527d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 NIBAN2 NECTIN3 ATP8A1 SCN1A

1.17e-041861145acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCB7 PAMR1 ESAM MED24 DNAH8

1.17e-04186114502418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

HIF3A LRRC4C ARHGEF15 ABCC8 SRPX

1.20e-041871145e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ESAM ARHGEF15 STAB1 MFNG ATP8A1

1.20e-04187114503de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164

1.26e-041891145dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell18-Airway-Epithelial-Neuroendocrine|Airway / Age, Tissue, Lineage and Cell class

CALCA FFAR3 ABCC8 SCN3A RIC3

1.26e-041891145144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 SLC1A5 SLC36A2 SCN3A SRPX

1.26e-04189114540cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESAM NECTIN3 ACKR4 MFNG ATP8A1

1.29e-04190114552213cd2a6a20772d4f49ba9ac0407abafa528db
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

ESAM HIF3A ARHGEF15 ABCC8 JAM3

1.29e-041901145812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FFAR2 ABCC8 SCN3A NHLH1 RIC3

1.29e-0419011455f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIGN PANX2 STAB1 SYNE3 ZC3H12D

1.29e-04190114563018acb7ad80415e861643162abdc2e55968ee4
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ESAM HIF3A BCR ARHGEF15 JAM3

1.29e-0419011450e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

ESAM HIF3A ARHGEF15 ABCC8 SRPX

1.32e-041911145c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MCM4 HMGCR SLC1A5 SYNE3 ATP8A1

1.32e-0419111459454f642c3621370fa23640b631301346b300950
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ARHGEF38 ATP8A1 SCN1A PLA2G4F FHIP1A

1.32e-041911145276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

ESAM HIF3A ARHGEF15 ABCC8 JAM3

1.32e-041911145322237793a1278bafb14e63cab688b353e352dcc
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESAM NECTIN3 ACKR4 MFNG ATP8A1

1.32e-04191114540e617d3c93f03ae87baf6c0b2304b617f5fe782
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESAM NECTIN3 ACKR4 ARHGEF15 MFNG

1.35e-041921145ff435141329e3e29fa9b08a4d5b2f55074e7f9ab
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

ARHGEF38 ATP8A1 SCN1A PLA2G4F TMEM164

1.35e-04192114506013a07e3a873b1d1c0451643c528593ac32a9c
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESAM NECTIN3 ACKR4 ARHGEF15 MFNG

1.35e-041921145f094ac378e635cf5820e8a8b7a0152073a51ceae
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ESAM HIF3A ARHGEF15 ABCC8 SRPX

1.39e-041931145c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A

5.77e-06101093DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A

5.77e-06101093DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.05e-05121093DOID:0060170 (implicated_via_orthology)
Diseaseciliopathy (implicated_via_orthology)

MKKS TMEM67 WDR11 MAP4K1

1.45e-05401094DOID:0060340 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A

7.17e-05221093DOID:2030 (implicated_via_orthology)
DiseaseBiliary calculi

HMGCR ABCG8

8.07e-0541092C0242216
DiseaseCommon Bile Duct Calculi

HMGCR ABCG8

8.07e-0541092C0009438
DiseaseManic

STAB1 TRANK1 SCN2A DNAH8

2.04e-04781094C0338831
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

2.81e-0471092C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

2.81e-0471092C0751057
Diseaseepilepsy (implicated_via_orthology)

SLC1A5 BDKRB1 SCN1A SCN2A SCN3A

3.56e-041631095DOID:1826 (implicated_via_orthology)
DiseaseFebrile Convulsions

SCN1A SCN2A

4.79e-0491092C0009952
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

4.79e-0491092C3502809
Diseasehandedness

PAMR1 TBC1D5 BCR PCDHGB4

6.55e-041061094EFO_0009902
Diseaseresponse to ondansetron, QT interval

SLC36A1 SLC36A2

7.28e-04111092EFO_0004682, EFO_0020997
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

1.03e-03131092C0751122
DiseaseBardet-Biedl syndrome (is_implicated_in)

MKKS TMEM67

1.20e-03141092DOID:1935 (is_implicated_in)
DiseaseMMR-related febrile seizures

SCN1A SCN2A

1.38e-03151092EFO_0006519
Disease5-oxoproline measurement

LRRC4C DNAH8

1.57e-03161092EFO_0010988
Diseasepancreatitis

HECTD4 ABCG8

1.57e-03161092EFO_0000278
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

1.57e-03161092C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

1.99e-03181092HP_0002373
DiseaseBardet-Biedl syndrome

MKKS TMEM67

1.99e-03181092cv:C0752166
DiseaseHypercholesterolemia, Familial

HMGCR ABCG8

1.99e-03181092C0020445
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGB5 LRRC4C PCDHGB4

2.34e-03711093EFO_0007878, EFO_0007979
Diseasealpha-tocopherol measurement

CACNA2D1 SCN3A

2.46e-03201092EFO_0007898
DiseaseParkinson's disease (is_implicated_in)

HMGCR VPS35 HTT

2.83e-03761093DOID:14330 (is_implicated_in)
Diseasedyslexia

TBC1D5 PANX2 FHIP1A HTT

3.11e-031621094EFO_0005424
DiseaseEtat Marbre

SCN1A HTT

3.25e-03231092C0266487
DiseaseBrugada Syndrome (disorder)

TRPM4 CACNA2D1

3.54e-03241092C1142166

Protein segments in the cluster

PeptideGeneStartEntry
FSPFLALSILVLLQA

CALCA

6

P06881
LFVLLVFLLPRRQLN

BDKRB1

56

P46663
LSAFVFPGELLLRLL

SLC1A5

86

Q15758
NLLLSLPEANLLTFL

BCR

1166

P11274
LRYLSLLCLLPLVAF

ADAM20

691

O43506
QRLILTPLSALLSLF

ARHGEF38

416

Q9NXL2
VLNLTRLTFFFLIPL

GPR18

186

Q14330
IPLFLFLAILRLSLN

GRAMD4

251

Q6IC98
RVFALTVLEFLLPLL

GPR20

196

Q99678
LALARALFARPDLLL

ABCF3

336

Q9NUQ8
QPRSDIFRLFDLVLL

ABCG8

271

Q9H221
SLLRRNQFILLVLFL

COLEC10

6

Q9Y6Z7
PLCLLLFSDLLLITQ

ARHGEF15

661

O94989
APLLALFSNLVEIRL

ANO9

561

A1A5B4
TFIILFNNLIPISLL

ATP8A1

346

Q9Y2Q0
FFREALLQISIPFLL

NIBAN2

491

Q96TA1
SEQPELQLRLFLLFL

OR8G2P

31

Q6IF36
AERLPVLFLFLLSLF

PCDHGB4

11

Q9UN71
TLLNTLAPLLLFRAR

LTN1

1381

O94822
DLLLESAFLELFILR

NR4A1

436

P22736
QFGLLPLLAFLLALA

SLC10A4

146

Q96EP9
LNLAVADLLLLFTLP

ACKR4

81

Q9NPB9
ISEPALLRTFLRFLL

FHIP1B

361

Q8N612
LSRFDLIFLLLDPQD

MCM4

641

P33991
ALILRAFLLTIPENA

MKKS

176

Q9NPJ1
IIFLTGLPANLLALR

FFAR2

16

O15552
LNEALPFFLLLIDLS

HMGCR

121

P04035
LINFLDLLDILIRSP

MED7

86

O43513
LEATYLLPLRLALLD

EXD1

251

Q8NHP7
RFVLASFALALLLPV

NAT14

56

Q8WUY8
FLRAPLNIIDILALL

KCNG2

246

Q9UJ96
LFLSLINDLFPGLQL

DNAH8

2066

Q96JB1
LASLNLLRLSVFFVP

ABCC11

421

Q96J66
ALFDPLLVVLLALQL

LRRC4C

21

Q9HCJ2
LCARLPDFFLLLLFR

JAM3

11

Q9BX67
VLALSLLLPKAFLSR

RIC3

16

Q7Z5B4
AERLPVLFLFLLSLF

PCDHGB5

11

Q9Y5G0
LNVPIESLRLRFALL

HECTD4

3506

Q9Y4D8
LALLPQRAVDLILSF

PLA2G4F

691

Q68DD2
NLTASDLLLLLFLPF

GPR42

56

O15529
ISEPALLEIFLRFIL

FHIP1A

346

Q05DH4
FNLAFAELRKLLPTL

NHLH1

91

Q02575
AFLTPLLRNIIISLA

HTT

2386

P42858
FLRLPLERLVFFLQS

KLHL26

201

Q53HC5
LDPFLLLISLFPFLT

CYP3A43

216

Q9HB55
LSLLLFFLPLAITAF

FFAR1

186

O14842
ILQQFLLSLTFPRLL

CACNA2D1

941

P54289
NLTASDLLLLLFLPF

FFAR3

56

O14843
LTSFLPAQLLRLYQL

SLC3A2

441

P08195
ALISDFLLFLLLRQP

CATIP

326

Q7Z7H3
LALNVDLLLFRGPFS

ATG9B

396

Q674R7
APLRTLLARQLVFFA

ATG9B

521

Q674R7
NLLRFLFLGLSALAP

ESAM

11

Q96AP7
FLSLPDLRCSLLLLV

ERP44

6

Q9BS26
FFVNDFSILRTLLPL

COL7A1

196

Q02388
HFSLFAQLELLLPFL

CNOT6

531

Q9ULM6
ALLQLLRAFPLARDV

MFNG

151

O00587
DLRIAQLRFLLSLPE

PSMD6

16

Q15008
LDVLSSLRLDPNFLL

FANCD2

246

Q9BXW9
NLSYVLLFRISLEPL

PRAMEF13

326

Q5VWM6
FTLVLPINIADFLLR

NPBWR1

86

P48145
LTFLQLLLISSLPRE

PAMR1

11

Q6UXH9
ALAALLLQLKLELPF

PANX2

36

Q96RD6
AVTAFLLLFLPRFLQ

TMEM67

21

Q5HYA8
LLLFLPRFLQAQTFS

TMEM67

26

Q5HYA8
LLQELRDPTLTFRLL

MAP4K1

781

Q92918
PELQLRLFLLFLGIC

OR8G3P

21

P0DMU2
RLLFPAVDDNLLKFL

TOP2B

836

Q02880
FLLAALVLSLILPRS

TMCO3

591

Q6UWJ1
LFLLLLFLLPIREED

SYNE3

936

Q6ZMZ3
RQPLTFLLILFLLFL

SYNE4

351

Q8N205
LLANFTLVLSIFILP

SLC16A14

386

Q7RTX9
NLSYVLLFRISLEPL

PRAMEF14

326

Q5SWL7
ENFLLFPLSLSFLLT

HIF3A

601

Q9Y2N7
PLNRVLANLFLLISS

MED24

896

O75448
LFLFQLLQLLLPTTT

SEMA4A

16

Q9H3S1
LSFLPFLVLLVLIRN

SLC36A2

206

Q495M3
NLSYVLLFRISLEPL

PRAMEF1

326

O95521
RFLLLLALAALLAFV

PXYLP1

6

Q8TE99
SLPALFNIGLLLFLV

SCN3A

1651

Q9NY46
RFLLSDQSLLLLPEY

SKIV2L

1041

Q15477
FSQLAPFEVRLLLLS

INTS5

931

Q6P9B9
NLSYVLLFRISLEPL

PRAMEF2

326

O60811
LQLRLLLRIPLYSFS

SRPX

401

P78539
ADFLFLSFQIIRLPL

MRGPRX4

71

Q96LA9
QFFDLRLLFLLTALR

RIC8A

161

Q9NPQ8
SLPALFNIGLLLFLV

SCN1A

1666

P35498
LLFQLSLPLNFLGTV

ABCB7

416

O75027
LLFLALLLQRTFLQA

ABCC8

361

Q09428
FSPFLALSILVLLQA

CALCA

6

P01258
QLPLILFLLFNEGLT

TMEM17

121

Q86X19
LIILDLSLFPLFQSS

TAS2R5

61

Q9NYW4
LLLLLRVLDPLLCDF

TBC1D17

466

Q9HA65
FLKLASALDLPLLRI

WASHC5

586

Q12768
QLALRLASLFPALFS

MINPP1

156

Q9UNW1
FLPFLVLLVFIRNLR

SLC36A1

201

Q7Z2H8
LLLPFIDSFQRVDLR

STOML1

106

Q9UBI4
ALLALLFPVVNTRLL

TMEM164

156

Q5U3C3
LIKAELAELPLRLFL

VPS35

571

Q96QK1
FLLSSRLFIEPRELL

RASGEF1C

66

Q8N431
LLFNLRDPRNLDLFL

SPOCD1

666

Q6ZMY3
SLPALFNIGLLLFLV

SCN2A

1656

Q99250
LLQQLDLVPAFSLFR

STAB1

1131

Q9NY15
FPFLTALLSLLNTLA

RPAP1

891

Q9BWH6
LSSPVLFQRLFSILL

PIGN

701

O95427
LLLFLLQINDILLAP

RALGAPB

166

Q86X10
DFLFPIVLLSLALLR

PRSS48

276

Q7RTY5
FPELSDLARLILLVQ

ZC3H12D

501

A2A288
LLPLAFFLLLATVFS

LTBR

231

P36941
VNLALADLLYLLSIP

UTS2R

91

Q9UKP6
PLLVALLCLFLRQLA

TNK1

216

Q13470
LAFNALLLLLLVAFI

TMC6

256

Q7Z403
RLLFGREFPLQDLLV

TBC1D5

336

Q92609
QEFLRDIFNLLFLLP

USP34

1811

Q70CQ2
DIFNLLFLLPSLKDR

USP34

1816

Q70CQ2
LLLLDASLPKPFFLR

TRANK1

1206

O15050
LLVPRASLALKAFLL

WDR11

846

Q9BZH6
LLLDPEFTLLQRCLL

WDR11

901

Q9BZH6
LLELPEFLLFLQHAI

TG

571

P01266
LLFLLLFSRVLLVDF

TRPM4

791

Q8TD43
LLLFPLLLFSRLCGA

NECTIN3

41

Q9NQS3