Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium/calmodulin-dependent protein kinase activity

CAMK2A CAMK2B CAMK2D CAMK2G

2.37e-05271264GO:0004683
GeneOntologyMolecularFunctionpeptide hormone binding

VIPR1 GCGR CRHR1 CRHR2 GLP1R

2.50e-05551265GO:0017046
GeneOntologyMolecularFunctionhormone binding

VIPR1 GCGR CRHR1 CRHR2 GLP1R ATP1A1

4.86e-051031266GO:0042562
GeneOntologyMolecularFunctioncalmodulin binding

IQCF2 CAMK2A IQCF1 CAMK2B CAMK2D CAMK2G OBSCN TRPV6

1.07e-042301268GO:0005516
GeneOntologyMolecularFunctioncorticotropin-releasing hormone receptor activity

CRHR1 CRHR2

1.18e-0431262GO:0043404
GeneOntologyMolecularFunctioncorticotrophin-releasing factor receptor activity

CRHR1 CRHR2

1.18e-0431262GO:0015056
GeneOntologyMolecularFunctionglucagon receptor activity

GCGR GLP1R

1.18e-0431262GO:0004967
GeneOntologyMolecularFunctioncarbon-sulfur lyase activity

CENPVL2 CENPVL3 CENPVL1

1.29e-04161263GO:0016846
GeneOntologyMolecularFunctionprotein-phosphatidylethanolamide deconjugating activity

ATG4A ATG4B

2.35e-0441262GO:0019786
GeneOntologyMolecularFunctionankyrin binding

OBSCN SPTBN4 ATP1A1

3.96e-04231263GO:0030506
GeneOntologyMolecularFunctionhelicase activity

CHD2 SRCAP IFIH1 HLTF DDX21 MOV10

5.03e-041581266GO:0004386
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

EZR ARFGEF2 ARFGEF1

5.10e-04251263GO:0034237
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

CHD2 VARS2 SRCAP TERF1 IFIH1 PSTK TRMT44 NYNRIN HLTF DDX21 MOV10 DNMT3L

7.93e-0464512612GO:0140640
GeneOntologyMolecularFunctioncadherin binding

EZR EPS8L2 SWAP70 OBSCN CDH19 EIF2S3 CDH8 PACSIN2

1.41e-033391268GO:0045296
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

VIPR1 GCGR CRHR1 CRHR2 GLP1R

1.56e-031331265GO:0008528
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD2 SRCAP HLTF

1.63e-03371263GO:0140658
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine kinase activity

CAMK2A CAMK2B

1.72e-03101262GO:0009931
GeneOntologyMolecularFunctionpeptide receptor activity

VIPR1 GCGR CRHR1 CRHR2 GLP1R

1.95e-031401265GO:0001653
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

CAMK2B POTEI

2.09e-03111262GO:0098973
GeneOntologyBiologicalProcessregulation of metal ion transport

HFE KLHL24 CAMK2A CAMK2B CAMK2D CAMK2G CRHR1 CRHR2 SPTBN4 TMEM168 GLP1R ATP1A1

3.65e-0549312212GO:0010959
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

HFE KLHL24 CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C CRHR1 CRHR2 SPTBN4 TMEM168 GLP1R ATP1A1

3.80e-0557712213GO:0043269
GeneOntologyCellularComponentcalcium- and calmodulin-dependent protein kinase complex

CAMK2A CAMK2B CAMK2D CAMK2G

5.68e-0951234GO:0005954
DomainCaMKII_AD

CAMK2A CAMK2B CAMK2D CAMK2G

1.85e-0941244PF08332
DomainCa/CaM-dep_prot_kinase-assoc

CAMK2A CAMK2B CAMK2D CAMK2G

1.85e-0941244IPR013543
DomainHormR

VIPR1 GCGR CRHR1 CRHR2 GLP1R

5.68e-07251245SM00008
DomainHRM

VIPR1 GCGR CRHR1 CRHR2 GLP1R

1.03e-06281245PF02793
Domain-

CAMK2A CAMK2B CAMK2D CAMK2G

1.26e-061312443.10.450.50
DomainNTF2-like_dom

CAMK2A CAMK2B CAMK2D CAMK2G

2.39e-06151244IPR032710
DomainGPCR_2_secretin-like_CS

VIPR1 GCGR CRHR1 CRHR2 GLP1R

2.84e-06341245IPR017983
DomainGPCR_2_extracellular_dom

VIPR1 GCGR CRHR1 CRHR2 GLP1R

6.50e-06401245IPR001879
DomainG_PROTEIN_RECEP_F2_1

VIPR1 GCGR CRHR1 CRHR2 GLP1R

6.50e-06401245PS00649
DomainG_PROTEIN_RECEP_F2_3

VIPR1 GCGR CRHR1 CRHR2 GLP1R

6.50e-06401245PS50227
Domain7tm_2

VIPR1 GCGR CRHR1 CRHR2 GLP1R

1.98e-05501245PF00002
DomainG_PROTEIN_RECEP_F2_2

VIPR1 GCGR CRHR1 CRHR2 GLP1R

1.98e-05501245PS00650
DomainIQ_motif_EF-hand-BS

IQCF2 IQCF1 OBSCN MYO15B IQCA1 CEP131

2.99e-05901246IPR000048
DomainIQ

IQCF2 IQCF1 OBSCN MYO15B IQCA1 CEP131

3.61e-05931246PS50096
DomainLMF

LMF1 LMF2

4.37e-0521242IPR009613
DomainGPCR_2_GLP1/glucagon_rcpt

GCGR GLP1R

4.37e-0521242IPR003290
DomainLMF1

LMF1 LMF2

4.37e-0521242PF06762
DomainANK

POTEB3 POTEG POTED POTEC POTEM TRPV6 ASB4 POTEI POTEA

4.59e-052511249SM00248
DomainGPCR_2_secretin-like

VIPR1 GCGR CRHR1 CRHR2 GLP1R

4.85e-05601245IPR000832
DomainGPCR_2-like

VIPR1 GCGR CRHR1 CRHR2 GLP1R

4.85e-05601245IPR017981
DomainANK_REPEAT

POTEB3 POTEG POTED POTEC POTEM TRPV6 ASB4 POTEI POTEA

4.88e-052531249PS50088
DomainANK_REP_REGION

POTEB3 POTEG POTED POTEC POTEM TRPV6 ASB4 POTEI POTEA

5.03e-052541249PS50297
DomainG_PROTEIN_RECEP_F2_4

VIPR1 GCGR CRHR1 CRHR2 GLP1R

5.26e-05611245PS50261
DomainAnkyrin_rpt

POTEB3 POTEG POTED POTEC POTEM TRPV6 ASB4 POTEI POTEA

6.39e-052621249IPR002110
DomainAnk_2

POTEB3 POTEG POTEC POTEM TRPV6 ASB4 POTEI POTEA

9.50e-052151248PF12796
DomainGPCR_2_CRF_rcpt

CRHR1 CRHR2

1.31e-0431242IPR003051
DomainAnk

POTEG POTED POTEC POTEM TRPV6 ASB4 POTEI POTEA

1.43e-042281248PF00023
DomainIQ

IQCF2 IQCF1 OBSCN IQCA1 CEP131

2.04e-04811245SM00015
Domain-

POTEB3 POTEG POTEC POTEM TRPV6 ASB4 POTEI POTEA

2.53e-0424812481.25.40.20
DomainDCB_dom

ARFGEF2 ARFGEF1

2.60e-0441242IPR032629
DomainPeptidase_C54

ATG4A ATG4B

2.60e-0441242PF03416
DomainSec7_C

ARFGEF2 ARFGEF1

2.60e-0441242IPR015403
DomainDUF1981

ARFGEF2 ARFGEF1

2.60e-0441242PF09324
DomainPeptidase_C54

ATG4A ATG4B

2.60e-0441242IPR005078
DomainSec7_N

ARFGEF2 ARFGEF1

2.60e-0441242IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

2.60e-0441242PF12783
DomainDCB

ARFGEF2 ARFGEF1

2.60e-0441242PF16213
DomainAnkyrin_rpt-contain_dom

POTEB3 POTEG POTEC POTEM TRPV6 ASB4 POTEI POTEA

2.97e-042541248IPR020683
DomainNUT

NUTM2A NUTM2B

4.32e-0451242IPR024310
DomainNUT_N

NUTM2A NUTM2B

4.32e-0451242IPR024309
DomainNUT

NUTM2A NUTM2B

4.32e-0451242PF12881
DomainINTEGRASE

GIN1 NYNRIN

4.32e-0451242PS50994
DomainIntegrase_cat-core

GIN1 NYNRIN

4.32e-0451242IPR001584
DomainHelicase_C

CHD2 SRCAP IFIH1 HLTF DDX21

7.37e-041071245PF00271
DomainHELICc

CHD2 SRCAP IFIH1 HLTF DDX21

7.37e-041071245SM00490
DomainHelicase_C

CHD2 SRCAP IFIH1 HLTF DDX21

7.69e-041081245IPR001650
DomainHELICASE_CTER

CHD2 SRCAP IFIH1 HLTF DDX21

8.01e-041091245PS51194
DomainHELICASE_ATP_BIND_1

CHD2 SRCAP IFIH1 HLTF DDX21

8.01e-041091245PS51192
DomainDEXDc

CHD2 SRCAP IFIH1 HLTF DDX21

8.01e-041091245SM00487
DomainHelicase_ATP-bd

CHD2 SRCAP IFIH1 HLTF DDX21

8.35e-041101245IPR014001
DomainSWIM

ZSWIM1 MAP3K1

8.98e-0471242PF04434
DomainCa/CaM-dep_Ca-dep_prot_Kinase

CAMK2A CAMK2B CAMK2D CAMK2G

1.15e-03691244IPR020636
DomainSNF2_N

CHD2 SRCAP HLTF

1.23e-03321243IPR000330
DomainSNF2_N

CHD2 SRCAP HLTF

1.23e-03321243PF00176
DomainIQ

IQCF2 IQCF1 OBSCN CEP131

1.28e-03711244PF00612
DomainZF_SWIM

ZSWIM1 MAP3K1

1.53e-0391242PS50966
DomainZnf_SWIM

ZSWIM1 MAP3K1

1.53e-0391242IPR007527
Domain-

ARFGEF2 ARFGEF1

4.34e-031512421.10.1000.11
DomainSec7

ARFGEF2 ARFGEF1

4.34e-03151242PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1

4.34e-03151242IPR023394
DomaintRNAsynth_Ia_anticodon-bd

VARS2 CEP131

4.34e-03151242IPR009080
DomainSEC7

ARFGEF2 ARFGEF1

4.94e-03161242PS50190
DomainSec7

ARFGEF2 ARFGEF1

4.94e-03161242SM00222
DomainSec7_dom

ARFGEF2 ARFGEF1

4.94e-03161242IPR000904
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

1.50e-0721875M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

1.50e-0721875M27944
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

1.93e-0722875MM15104
PathwayREACTOME_LONG_TERM_POTENTIATION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

2.46e-0723875M27949
PathwayREACTOME_CAMK_IV_MEDIATED_PHOSPHORYLATION_OF_CREB

CAMK2A CAMK2B CAMK2D CAMK2G

2.76e-0710874M26910
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

VIPR1 GCGR CRHR1 CRHR2 GLP1R

3.09e-0724875MM15992
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

VIPR1 GCGR CRHR1 CRHR2 GLP1R

3.09e-0724875M39643
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

3.84e-0725875M47511
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

1.29e-0614874M47386
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

1.29e-0614874M47388
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

CAMK2A CAMK2B CAMK2D CAMK2G MOV10

1.41e-0632875M27900
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

1.65e-0633875M39875
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

1.75e-0615874M47385
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

2.24e-0635875MM15109
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

3.03e-0617874M47387
PathwayPID_IFNG_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G MAP3K1

4.43e-0640875M161
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

4.89e-0619874M47957
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G

4.89e-0619874MM15473
PathwayREACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR

CAMK2A CAMK2B CAMK2D CAMK2G

6.08e-0620874M17670
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

7.16e-0644875M27934
PathwayWP_NOCGMPPKG_MEDIATED_NEUROPROTECTION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

9.97e-0647875M39531
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CAMK2A CAMK2B CAMK2D CAMK2G

1.10e-0523874MM14953
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

1.10e-0523874M47512
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

1.31e-0524874M47509
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

1.55e-0525874M47510
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

1.99e-0554875M27460
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

1.99e-0554875MM15202
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

2.18e-0555875M971
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G

2.47e-0528874M837
PathwayKEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

2.47e-0528874M47508
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

2.59e-0557875MM15643
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

CAMK2A CAMK2B CAMK2D CAMK2G

2.86e-0529874MM15028
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

VIPR1 GCGR CRHR1 CRHR2 GLP1R

3.33e-0560875MM14964
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

CAMK2A CAMK2B CAMK2D CAMK2G

3.75e-0531874M7223
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

CAMK2A CAMK2B CAMK2D CAMK2G MOV10

4.23e-0563875M27862
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CAMK2A CAMK2B CAMK2D CAMK2G

4.26e-0532874M27455
PathwayREACTOME_RAF_ACTIVATION

CAMK2A CAMK2B CAMK2D CAMK2G

5.45e-0534874M27556
PathwayREACTOME_RAF_ACTIVATION

CAMK2A CAMK2B CAMK2D CAMK2G

6.12e-0535874MM15271
PathwayKEGG_OOCYTE_MEIOSIS

CAMK2A CAMK2B CAMK2D CAMK2G ANAPC2 ESPL1

6.92e-05113876M16817
PathwayKEGG_LONG_TERM_POTENTIATION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

7.04e-0570875M3115
PathwayREACTOME_CA_DEPENDENT_EVENTS

CAMK2A CAMK2B CAMK2D CAMK2G

7.65e-0537874M749
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CAMK2A CAMK2B CAMK2D CAMK2G

8.51e-0538874M27255
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO4 CAMK2A CAMK2B CAMK2D CAMK2G TRPV6 ATP1A1

1.06e-04176877MM15718
PathwayREACTOME_DAG_AND_IP3_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G

1.15e-0441874M512
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO4 CAMK2A CAMK2B CAMK2D CAMK2G TRPV6 ATP1A1

1.35e-04183877M997
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

CAMK2A CAMK2B CAMK2D CAMK2G

1.52e-0444874M39845
PathwayREACTOME_SIGNALING_BY_MODERATE_KINASE_ACTIVITY_BRAF_MUTANTS

CAMK2A CAMK2B CAMK2D CAMK2G

1.66e-0445874M27623
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

CAMK2A CAMK2B CAMK2D CAMK2G AAAS

2.57e-0492875MM14951
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

2.84e-0494875M2843
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

VIPR1 GCGR CRHR1 CRHR2 GLP1R

2.84e-0494875M797
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

CAMK2A CAMK2B CAMK2D CAMK2G

3.38e-0454874M26911
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G IRF7

3.45e-0498875M965
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

CAMK2A CAMK2B CAMK2D CAMK2G AAAS

3.97e-04101875M27253
PathwayKEGG_GNRH_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G MAP3K1

3.97e-04101875M1979
PathwayREACTOME_CARDIAC_CONDUCTION

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

4.34e-04103875MM15196
PathwayKEGG_GLIOMA

CAMK2A CAMK2B CAMK2D CAMK2G

6.88e-0465874M1835
PathwayREACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS

CAMK2A CAMK2B CAMK2D CAMK2G

6.88e-0465874M38994
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO4 HFE LMF1 CAMK2A CAMK2B CAMK2D CAMK2G EIF2S3B LMF2 EIF2S3 TRPV6 ATP1A1

9.34e-046818712MM14985
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

CDH19 CDH8 MOV10

9.89e-0432873M48012
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII_CAMKK_CAMKIV_CASCASDE

CAMK2B CAMK2G

1.03e-038872M10546
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

CAMK2A CAMK2B CAMK2D CAMK2G EIF2S3B TERF1 AAAS EIF2S3 ANAPC2 MIOS

1.07e-035058710MM15548
PathwayREACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS

VIPR1 GCGR GLP1R

1.08e-0333873MM15066
PathwayREACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS

VIPR1 GCGR GLP1R

1.08e-0333873M10322
PathwayKEGG_NEUROTROPHIN_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G MAP3K1

1.08e-03126875M16763
PathwayWP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3

CAMK2A CAMK2B CAMK2D CAMK2G

1.18e-0375874M39568
PathwayREACTOME_CARDIAC_CONDUCTION

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

1.25e-03130875M27454
PathwayREACTOME_RECYCLING_OF_EIF2_GDP

EIF2S3B EIF2S3

1.32e-039872MM15418
PathwayREACTOME_INTERFERON_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G IRF7 AAAS EIF2S3

1.48e-03273877M983
PathwayREACTOME_CELLULAR_RESPONSE_TO_MITOCHONDRIAL_STRESS

EIF2S3B EIF2S3

1.64e-0310872MM17234
PathwayBIOCARTA_EIF_PATHWAY

EIF2S3B EIF2S3

1.64e-0310872MM1394
PathwayBIOCARTA_EIF2_PATHWAY

EIF2S3B EIF2S3

1.64e-0310872MM1469
PathwayWP_MRNA_VACCINE_ACTIVATION_OF_DENDRITIC_CELL_AND_INDUCTION_OF_IFN1

IRF7 IFIH1

1.64e-0310872M45510
PathwayREACTOME_ONCOGENIC_MAPK_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G

1.64e-0382874M27626
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

1.73e-03140875M42572
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

VIPR1 GCGR CRHR1 CRHR2 GLP1R

1.90e-03143875MM15055
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

1.96e-03144875MM14501
PathwayREACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES

LMF1 LMF2

2.00e-0311872MM15559
PathwayKEGG_ERBB_SIGNALING_PATHWAY

CAMK2A CAMK2B CAMK2D CAMK2G

2.04e-0387874M12467
PathwayREACTOME_OPIOID_SIGNALLING

CAMK2A CAMK2B CAMK2D CAMK2G

2.31e-0390874M6467
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

CDH19 SDK1 CDH8 MOV10

2.31e-0390874M820
PathwayREACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR

EIF2S3B EIF2S3

2.39e-0312872MM14981
PathwayWP_ERBB_SIGNALING

CAMK2A CAMK2B CAMK2D CAMK2G

2.50e-0392874M39715
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

CAMK2A CAMK2B CAMK2D CAMK2G CRHR1

2.62e-03154875MM15974
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

CAMK2A CAMK2B CAMK2D CAMK2G CRHR1

2.77e-03156875M39475
PathwayKEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION

ATG4A ATG4B

2.81e-0313872M47458
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

VIPR1 GCGR CRHR1 CRHR2 GLP1R

2.85e-03157875M4904
PathwayKEGG_MELANOGENESIS

CAMK2A CAMK2B CAMK2D CAMK2G

3.51e-03101874M7761
PathwayREACTOME_MUSCLE_CONTRACTION

CAMK2A CAMK2B CAMK2D CAMK2G ATP1A1

3.53e-03165875MM15026
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

IRF7 IFIH1

3.75e-0315872M953
PathwayKEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_ANAPHASE

ANAPC2 ESPL1

4.27e-0316872M47871
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING

ANAPC2 ESPL1

4.27e-0316872M47476
Pubmed

Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system.

CAMK2A CAMK2B CAMK2D CAMK2G

1.98e-104132410381553
Pubmed

Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells.

CAMK2A CAMK2B CAMK2D CAMK2G

1.98e-104132417367784
Pubmed

[Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions].

CAMK2A CAMK2B CAMK2D CAMK2G

1.98e-104132411889801
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

5.66e-101213258665664
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

CAMK2A CAMK2B CAMK2D CAMK2G GRIN2C

5.66e-1012132512815021
Pubmed

Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein.

CAMK2A CAMK2B CAMK2D CAMK2G

9.88e-105132411013247
Pubmed

Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.

CAMK2A CAMK2B CAMK2D CAMK2G

9.88e-105132418218981
Pubmed

Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.

CAMK2A CAMK2B CAMK2D CAMK2G

9.88e-105132421209221
Pubmed

Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.

CAMK2A CAMK2B CAMK2D CAMK2G

9.88e-105132414722083
Pubmed

Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.

CAMK2A CAMK2B CAMK2D CAMK2G

9.88e-105132416436603
Pubmed

Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6.

CAMK2A CAMK2B CAMK2D CAMK2G

2.96e-096132418948074
Pubmed

Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.

POTEB3 POTEG POTED POTEA

6.88e-097132415276201
Pubmed

Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II.

CAMK2A CAMK2B CAMK2D CAMK2G

6.88e-09713249115241
Pubmed

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.

POTEB3 POTED POTEC POTEA

1.37e-088132412475935
Pubmed

Ca(2+)/CaM-dependent kinases: from activation to function.

CAMK2A CAMK2B CAMK2D CAMK2G

1.37e-088132411264466
Pubmed

Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.

CAMK2A CAMK2B CAMK2D CAMK2G

1.37e-088132420668654
Pubmed

Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.

CAMK2A CAMK2B CAMK2D CAMK2G

2.46e-089132412660151
Pubmed

Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.

POTED POTEM POTEI POTEA

2.46e-089132416364570
Pubmed

CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo.

CAMK2A CAMK2B CAMK2D CAMK2G

4.09e-0810132428361052
Pubmed

The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo.

CAMK2A CAMK2B CAMK2D CAMK2G

4.09e-0810132419776387
Pubmed

Identification of novel human tumor cell-specific CaMK-II variants.

CAMK2B CAMK2D CAMK2G

5.34e-08313239060999
Pubmed

Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.

CAMK2B CAMK2D CAMK2G

5.34e-083132310819240
Pubmed

Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.

CAMK2B CAMK2D CAMK2G

5.34e-083132320844140
Pubmed

Calcium/calmodulin-dependent protein kinase II and calmodulin: regulators of the meiotic spindle in mouse eggs.

CAMK2A CAMK2B CAMK2G

5.34e-08313239882483
Pubmed

Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma.

CAMK2A CAMK2B CAMK2D CAMK2G

9.58e-081213248615909
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

CAMK2A CAMK2B CAMK2D CAMK2G

1.93e-0714132410373510
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

CAMK2A CAMK2B CAMK2D CAMK2G

2.62e-0715132414622581
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

CAMK2A CAMK2B CAMK2D CAMK2G

2.62e-071513249481670
Pubmed

Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin.

CAMK2A CAMK2B CAMK2G

5.31e-075132311160423
Pubmed

Alpha-kinase anchoring protein alphaKAP interacts with SERCA2A to spatially position Ca2+/calmodulin-dependent protein kinase II and modulate phospholamban phosphorylation.

CAMK2A CAMK2D CAMK2G

5.31e-075132319671701
Pubmed

PTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning.

CAMK2A CAMK2B CAMK2G

5.31e-075132328636948
Pubmed

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

CAMK2A CAMK2B CAMK2D CAMK2G

5.82e-0718132418311135
Pubmed

Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2.

CAMK2A CAMK2D CAMK2G

1.06e-066132316120608
Pubmed

Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.

CENPVL2 CENPVL3 CENPVL1

1.06e-066132327250503
Pubmed

Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.

POTEG POTEC POTEM

1.06e-066132317171436
Pubmed

Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.

CAMK2A CAMK2D CAMK2G

1.06e-066132311972023
Pubmed

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice.

CAMK2A CAMK2D SPTBN4

1.06e-066132320877009
Pubmed

ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion.

CAMK2A CAMK2D CAMK2G

1.85e-067132334932950
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

CAMK2A CAMK2B CAMK2G CNTNAP1 NIPSNAP1 EIF2S3B NDUFA13 EIF2S3 ATP1A1 GNL1 CCDC9 PACSIN2

4.71e-066211321222794259
Pubmed

N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.

CAMK2A CAMK2B GRIN2C

6.29e-0610132319332541
Pubmed

Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors.

VIPR1 CRHR1 GLP1R

6.29e-0610132315670850
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

EZR CAMK2A CAMK2B CAMK2D CAMK2G THTPA ATG4B ATP1A1 PACSIN2

6.64e-06341132929791485
Pubmed

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

VIPR1 GCGR CRHR1 CRHR2 GLP1R

7.25e-0670132512036966
Pubmed

PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome.

CAMK2A CAMK2D CAMK2G

8.62e-0611132321491429
Pubmed

Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells.

ATG4A ATG4B

1.43e-052132237701987
Pubmed

Expression and subcellular localization of CRH and its receptors in human endometrial cancer.

CRHR1 CRHR2

1.43e-052132219433256
Pubmed

The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.

CAMK2B CAMK2G

1.43e-052132215294044
Pubmed

A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme.

CAMK2A CAMK2B

1.43e-052132221884935
Pubmed

Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling.

CRHR1 CRHR2

1.43e-052132219098121
Pubmed

Design and preparation of the class B G protein-coupled receptors GLP-1R and GCGR for 19 F-NMR studies in solution.

GCGR GLP1R

1.43e-052132233369025
Pubmed

Localization of a (CA)n repeat in glucagon-like peptide-1 receptor gene (Glp1r) to proximal mouse chromosome 17 and its linkage to other markers.

GCGR GLP1R

1.43e-05213227613039
Pubmed

Corticotropin-releasing factor receptors induce calcium mobilization through cross-talk with Gq-coupled receptors.

CRHR1 CRHR2

1.43e-052132220594969
Pubmed

Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome.

CRHR1 CRHR2

1.43e-052132237543650
Pubmed

Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation.

CAMK2A CAMK2B

1.43e-052132232149607
Pubmed

[PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice].

CAMK2D CAMK2G

1.43e-052132238597448
Pubmed

Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents.

GCGR GLP1R

1.43e-052132223203689
Pubmed

Quantitative proteomics analysis of CaMKII phosphorylation and the CaMKII interactome in the mouse forebrain.

CAMK2A CAMK2B

1.43e-052132225650780
Pubmed

Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.

CRHR1 CRHR2

1.43e-052132222467522
Pubmed

Protein Kinase A Subunit Balance Regulates Lipid Metabolism in Caenorhabditis elegans and Mammalian Adipocytes.

CAMK2A CAMK2B

1.43e-052132227496951
Pubmed

Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice.

GCGR GLP1R

1.43e-052132219602537
Pubmed

Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.

GCGR GLP1R

1.43e-052132227226600
Pubmed

Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice.

CAMK2A CAMK2D

1.43e-052132220538682
Pubmed

CaMK-II oligomerization potential determined using CFP/YFP FRET.

CAMK2B CAMK2D

1.43e-052132216185778
Pubmed

Domain structure responsible for the different properties between alpha and beta Ca2+/calmodulin-dependent protein kinase II analyzed by their chimera enzymes.

CAMK2A CAMK2B

1.43e-052132218703025
Pubmed

Changes in Ca(2+)/calmodulin-dependent protein kinase II activity and its relation to performance in passive avoidance response and long-term potentiation formation in mice prenatally exposed to diethylstilbestrol.

CAMK2A CAMK2B

1.43e-052132217184923
Pubmed

Decreased expression of calmodulin kinase II and calcineurin messenger RNAs in the mouse hippocampus after kainic acid-induced seizures.

CAMK2A CAMK2B

1.43e-05213229523577
Pubmed

Dysregulation of bladder corticotropin-releasing hormone receptor in the pathogenesis of human interstitial cystitis/bladder pain syndrome.

CRHR1 CRHR2

1.43e-052132231844086
Pubmed

Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance.

CAMK2D CAMK2G

1.43e-052132234303021
Pubmed

Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin.

CRHR1 CRHR2

1.43e-052132217170072
Pubmed

Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.

CRHR1 CRHR2

1.43e-052132214724656
Pubmed

Molecular cloning and sequence analyses of calcium/calmodulin-dependent protein kinase II from fetal and adult human brain. Sequence analyses of human brain calciuum/calmodulin-dependent protein kinase II.

CAMK2A CAMK2B

1.43e-052132211710563
Pubmed

Joint effect of RRP9 and DDX21 on development of colorectal cancer and keloid.

RRP9 DDX21

1.43e-052132237988222
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

1.43e-052132223918382
Pubmed

Expression of corticotropin-releasing hormone receptor type 1 and type 2 in human pregnant myometrium.

CRHR1 CRHR2

1.43e-052132217959885
Pubmed

Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts.

CRHR1 CRHR2

1.43e-052132218325997
Pubmed

Association study between the corticotropin-releasing hormone receptor 2 gene and suicidality in bipolar disorder.

CRHR1 CRHR2

1.43e-052132217532191
Pubmed

RRP9 and DDX21 as new biomarkers of colorectal cancer.

RRP9 DDX21

1.43e-052132237904456
Pubmed

The highly selective CRF(2) receptor antagonist K41498 binds to presynaptic CRF(2) receptors in rat brain.

CRHR1 CRHR2

1.43e-052132212110614
Pubmed

HPA axis genes may modulate the effect of childhood adversities on decision-making in suicide attempters.

CRHR1 CRHR2

1.43e-052132223177644
Pubmed

Different effects of chronic social defeat on social behavior and the brain CRF system in adult male C57 mice with different susceptibilities.

CRHR1 CRHR2

1.43e-052132232057826
Pubmed

Identification of Nipsnap1 as a novel auxiliary protein inhibiting TRPV6 activity.

NIPSNAP1 TRPV6

1.43e-052132218392847
Pubmed

Distinct distribution of corticotropin releasing factor receptors in human breast cancer.

CRHR1 CRHR2

1.43e-052132220630588
Pubmed

Synaptic memory requires CaMKII.

CAMK2A CAMK2B

1.43e-052132234908526
Pubmed

A role for CaMKII in T cell memory.

CAMK2B CAMK2G

1.43e-052132210693762
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

1.43e-052132217360629
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

1.43e-052132210716990
Pubmed

Measurement of the Activity of the Atg4 Cysteine Proteases.

ATG4A ATG4B

1.43e-052132228253956
Pubmed

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.

CAMK2A CAMK2B

1.43e-052132229100089
Pubmed

Effect of CRHR1 and CRHR2 gene polymorphisms and childhood trauma in suicide attempt.

CRHR1 CRHR2

1.43e-052132230874897
Pubmed

Expression and functional characterization of membrane-integrated mammalian corticotropin releasing factor receptors 1 and 2 in Escherichia coli.

CRHR1 CRHR2

1.43e-052132224465390
Pubmed

CaMKII is essential for the function of the enteric nervous system.

CAMK2A CAMK2G

1.43e-052132222952977
Pubmed

Ligand-Receptor Interactions and Machine Learning in GCGR and GLP-1R Drug Discovery.

GCGR GLP1R

1.43e-052132233920024
Pubmed

Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.

CAMK2A CAMK2D

1.43e-052132221252154
Pubmed

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia.

LMF1 LMF2

1.43e-052132217994020
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

1.43e-052132218203920
Pubmed

Differential effects of oxyntomodulin and GLP-1 on glucose metabolism.

GCGR GLP1R

1.43e-052132222621866
Pubmed

Downregulation of ARFGEF1 and CAMK2B by promoter hypermethylation in breast cancer cells.

CAMK2B ARFGEF1

1.43e-052132221871176
Pubmed

CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation.

CAMK2D CAMK2G

1.43e-052132231619570
Pubmed

Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway.

CAMK2D CAMK2G

1.43e-052132229992531
Pubmed

Tissue-specific and glucose-dependent expression of receptor genes for glucagon and glucagon-like peptide-1 (GLP-1).

GCGR GLP1R

1.43e-05213229105899
InteractionCAMK2N1 interactions

CAMK2A CAMK2B CAMK2D CAMK2G

3.07e-07101274int:CAMK2N1
InteractionPOTED interactions

POTEB3 POTED POTEC

9.73e-0741273int:POTED
InteractionPOTEC interactions

POTEB3 POTEG POTED POTEC

1.03e-06131274int:POTEC
InteractionCIBAR2 interactions

CAMK2B CAMK2D CAMK2G

8.40e-0671273int:CIBAR2
InteractionCAMK2N2 interactions

CAMK2A CAMK2B CAMK2G

8.40e-0671273int:CAMK2N2
InteractionPDE4A interactions

CAMK2A CAMK2B CAMK2D CAMK2G

3.63e-05301274int:PDE4A
InteractionPOTEG interactions

POTEG POTEC POTEA

5.16e-05121273int:POTEG
InteractionTTC5 interactions

SWAP70 CAMK2A CAMK2B CAMK2D CAMK2G

5.60e-05651275int:TTC5
Cytoband3p21.2

IQCF2 IQCF1 RRP9

2.18e-051913233p21.2
CytobandEnsembl 112 genes in cytogenetic band chr10q22

CAMK2G ZNF503-AS2 NUTM2E NUTM2B P4HA1 DDX21

3.28e-052081326chr10q22
CytobandXp11.22

CENPVL2 CENPVL3 CENPVL1

5.18e-04541323Xp11.22
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEG POTED POTEC POTEM POTEI POTEA

5.41e-1213726685
GeneFamilyAnkyrin repeat domain containing

POTEG POTED POTEC POTEM TRPV6 ASB4 POTEI POTEA

5.25e-06242728403
GeneFamilyCorticotropin releasing hormone receptors

CRHR1 CRHR2

1.56e-052722266
GeneFamilyGlucagon receptor family

GCGR GLP1R

2.32e-046722269
GeneFamilyZinc fingers SWIM-type|Mitogen-activated protein kinase kinase kinases

ZSWIM1 MAP3K1

5.53e-04972290
GeneFamilyCD molecules|Type II classical cadherins

CDH19 CDH8

1.19e-03137221186
CoexpressionGSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN

SHFL IRF7 IFIH1 SLC25A43 TMEM168 NYNRIN HLTF MOV10

6.67e-061991298M3286
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

CAMK2A DDR2 FREM1 SLIT2 THBS2 ENPEP SDK1

1.80e-061931327ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell368C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LMF1 APOBEC3D IRF7 VARS2 MYO15B CHST15

1.22e-051711326f3bf5805823d5733b58742172e7668725ce82931
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR SWAP70 CAMK2D MAP3K1 DDX21 CCDC191

1.30e-051731326d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8L2 PCDHGA11 CAMK2B CAMK2D FBXL12 ENPEP

1.43e-05176132629cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ANO4 CAMK2A DDR2 MXRA8 SLIT2 THBS2

1.43e-0517613262e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8L2 PCDHGA11 CAMK2B CAMK2D FBXL12 ENPEP

1.43e-05176132601774a86d7d92f31a056b753f9844f923038003e
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

ANO4 CAMK2A DDR2 MXRA8 SLIT2 THBS2

1.43e-051761326f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDR2 MXRA8 FREM1 SLIT2 THBS2 ENPEP

1.96e-0518613265473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

DDR2 MXRA8 FREM1 TRIL SLIT2 ENPEP

2.08e-0518813263f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

MXRA8 FREM1 TRIL SLIT2 CHST15 ENPEP

2.27e-0519113263379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 FREM1 SLIT2 THBS2 SDK1

2.34e-0519213264e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR SWAP70 MAP3K1 SLC25A43 DDX21 CCDC191

2.41e-05193132608696a99309f5b088692ddac8cca35413b5e810d
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

EVC2 DDR2 MXRA8 CDH19 SLIT2 THBS2

2.48e-051941326d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

DDR2 CDH19 SLIT2 THBS2 DDX21 SDK1

2.48e-051941326803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

EVC2 DDR2 CDH19 FREM1 SLIT2 THBS2

2.55e-051951326f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

CAMK2A DDR2 FREM1 SLIT2 ENPEP SDK1

2.55e-05195132661c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EVC2 DDR2 FREM1 NUTM2E TRIL THBS2

2.70e-05197132631c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

DDR2 MXRA8 FREM1 SLIT2 THBS2 SDK1

2.78e-05198132626e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

VIPR1 MXRA8 CDH19 SLIT2 THBS2 SDK1

2.78e-051981326bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

DDR2 FREM1 SLIT2 THBS2 ENPEP SDK1

2.86e-0519913264bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IRF7 CHD2 IFIH1 KANSL1 DDX21 PHIP

2.94e-05200132612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DDR2 FREM1 SLIT2 THBS2 ENPEP SDK1

2.94e-052001326cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

POTEG POTEC SLIT2 POTEM INAVA

5.33e-05136132527a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

POTEG POTEC SLIT2 POTEM INAVA

5.33e-05136132588b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EVC2 FBXL12 GRIN2C NUTM2E INAVA

7.96e-0514813251186ee0d15244fee74c1d09df3967c1b69f8ddce
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TLCD1 GRIN2C CDH19 TRIL

9.31e-05153132595b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TLCD1 GRIN2C CDH19 TRIL

9.31e-051531325b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TLCD1 GRIN2C CDH19 TRIL

9.31e-0515313253ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TLCD1 GRIN2C CDH19 TRIL

1.05e-0415713250551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCellfrontal_cortex-Non-neuronal-astrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TLCD1 GRIN2C CDH19 TRIL

1.05e-041571325803af734d7f775d294391e2b84e472a732e18cef
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TLCD1 GRIN2C CDH19 TRIL

1.05e-0415713259aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

HFE SHFL IRF7 ZNF365 IFIH1

1.12e-04159132597c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

HFE SHFL IRF7 ZNF365 IFIH1

1.12e-041591325fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

1.18e-041611325b19f82dd98a3064581793711bb70373f18abecd9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VIPR1 CAMK2B CRHR1 ZMYND10 CDH8

1.18e-041611325ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR SWAP70 MAP3K1 DDX21 CCDC191

1.25e-0416313256bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

LMF1 APOBEC3D IRF7 MYO15B CHST15

1.40e-0416713251e2fc1637769405a61f4c7e44945712a1888a299
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

CNTNAP1 CRHR2 SLIT2 GLP1R SDK1

1.44e-04168132500646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

VARS2 SPTBN4 GLP1R POTEI CDH8

1.48e-04169132596a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

VIPR1 OBSCN GLP1R BTNL9 PKN3

1.57e-041711325bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH19 FREM1 THBS2 GLP1R SDK1

1.57e-0417113254ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8L2 PCDHGA11 CAMK2B FBXL12 ENPEP

1.70e-041741325268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8L2 PCDHGA11 CAMK2B FBXL12 ENPEP

1.70e-0417413254cdf2eedc28d88d18241ee390092426fdf849e79
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ANO4 VWA3A FREM1 TRIL ZMYND10

1.79e-0417613258e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EPS8L2 DDR2 CDH19 THBS2 CDH8

1.84e-041771325915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C22orf42 CAMK2B FAM131C RASSF10 SPTBN4

1.84e-04177132543dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

1.94e-041791325b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM131C RASSF10 PEBP4 DNMT3L DUOXA2

1.99e-04180132535c73670da90cb6924e822a2426d13a675685f09
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

MXRA8 FREM1 TRIL SLIT2 ENPEP

1.99e-041801325adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LMF1 CAMK2A ZNF365 SLIT2 IQCA1

2.04e-04181132557994ff4ecffb15653aee00644d9f887f5e3461d
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHFL CAMK2A SIRT3 IQCA1 RRP9

2.15e-041831325b60638680b1882b5a47f5dbce08f545e93bb4d0f
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRF7 CHD2 IFIH1 PKN3 MOV10

2.26e-041851325f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

DDR2 FREM1 SLIT2 THBS2 SDK1

2.26e-041851325a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 CAMK2D CRHR2 PEBP4

2.32e-041861325d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 DDR2 CNTNAP1 MXRA8 THBS2

2.37e-041871325b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 DDR2 CNTNAP1 MXRA8 THBS2

2.37e-0418713259fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 DDR2 CNTNAP1 MXRA8 THBS2

2.37e-041871325e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DDR2 CDH19 FREM1 SLIT2 THBS2

2.43e-041881325fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

VWA3A ZMYND10 IQCA1 CCDC180 CCDC191

2.43e-0418813258f30535a32968a81a304315a49c0d90a77d36948
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.43e-0418813256740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 FREM1 SLIT2 SDK1

2.49e-041891325a153b83314cf52808f685296cff8c95af3f4983d
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.49e-041891325dc5164591dea45b420798b94dda211be03daa70c
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.55e-0419013251196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DDR2 MXRA8 FAM131C SLIT2 PLA2G4F

2.55e-04190132581f8f2cddf4c51b879f315260cd1fca80355a371
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DDR2 MXRA8 FAM131C SLIT2 PLA2G4F

2.55e-04190132520106e5213f6a7560554b8b4f84b23c5554ba975
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CAMK2D DDR2 SLIT2 THBS2 SDK1

2.55e-04190132545df8fee00f8949937863159d7aa042e72748d9b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

C22orf42 CAMK2B ZNF503-AS2 TXNDC16 ATP1A1

2.55e-0419013256e92c78799f34b31d098854503c796edb0dc7f80
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

DDR2 FREM1 SLIT2 THBS2 SDK1

2.55e-0419013253a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DDR2 MXRA8 FAM131C SLIT2 PLA2G4F

2.55e-041901325877b544decf302e0d41be23dffa1861f79c70914
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MXRA8 FREM1 SLIT2 THBS2 SDK1

2.55e-041901325d60395739458d7f47a3350ade751fe3819500320
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 FREM1 SLIT2 THBS2 SDK1

2.62e-041911325b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAMK2D SLIT2 THBS2 DDX21 SDK1

2.62e-04191132508720998aa55131d7377c4c67c4c935865bd7d79
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.62e-041911325a05e9a7eb137d804570dd7d8905975d735738767
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR KLHL24 ARFGEF2 CHD2 DDX21

2.62e-0419113251ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_mem-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ANO4 EZR SWAP70 POTEG POTEM

2.68e-041921325185dd150d3345cd29625052a46f3ed89f2a9a8f6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 FREM1 SLIT2 SDK1

2.68e-041921325dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 SLIT2 THBS2 SDK1

2.68e-041921325162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell18-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

EZR KLHL24 EPS8L2 SRCAP ATP1A1

2.68e-0419213259fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.68e-0419213252802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 FREM1 SLIT2 SDK1

2.68e-0419213253d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DDR2 MXRA8 FREM1 SLIT2 THBS2

2.68e-041921325e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.68e-0419213250afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCellP03-Mesenchymal-mesenchymal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.68e-041921325e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

VWA3A ZMYND10 IQCA1 CC2D2A CCDC191

2.75e-041931325c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.75e-0419313258d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A VIPR1 DDR2 MXRA8 SPTBN4

2.75e-0419313252483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.75e-0419313251b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 FREM1 SLIT2 SDK1

2.75e-041931325fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR EPS8L2 INAVA ATP1A1 DNMT3L

2.81e-0419413251531dcace28a14bd700e909a027426a8cee20337
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.81e-041941325f15e81ff12525523c62d13105cf264ea72205e2e
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.81e-0419413254f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 MXRA8 FREM1 SLIT2 SDK1

2.81e-0419413256e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 POTEG POTEM BTNL9

2.81e-04194132540c7f9bd69a8e843b81972e25a67f591021415dd
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EZR CHD2 PEBP4 PLA2G4F PACSIN2

2.81e-04194132597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

VWA3A ZMYND10 IQCA1 CC2D2A CCDC191

2.81e-0419413255aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CAMK2D DDR2 FREM1 SLIT2 SDK1

2.81e-04194132589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 POTEG POTEM BTNL9

2.88e-04195132551e6cfecd66a874673d0b79a295489a358bddfd5
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.88e-041951325cbe518b465b4ef32797ae6b608219207c08493df
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.88e-041951325b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXRA8 FREM1 TRIL SLIT2 ENPEP

2.88e-0419513251c1135be421af98cd0077bec1ff2c4158d42aa21
DrugTetracaone hydrochloride [136-47-0]; Down 200; 13.2uM; HL60; HG-U133A

ATG4A HFE EZR KLHL24 SHFL GIN1 IRF7 IFIH1 AAAS CEP131

1.66e-07199126101739_DN
Diseaseheart conduction disease (implicated_via_orthology)

CAMK2A CAMK2B CAMK2D CAMK2G

8.01e-06321184DOID:10273 (implicated_via_orthology)
DiseaseMEHMO syndrome (implicated_via_orthology)

EIF2S3B EIF2S3

1.59e-0521182DOID:0060801 (implicated_via_orthology)
Diseaseaminoacylase-1 measurement

IQCF1 RRP9

1.59e-0521182EFO_0020141
Diseasefunctional colonic disease (biomarker_via_orthology)

CRHR1 CRHR2

4.74e-0531182DOID:3877 (biomarker_via_orthology)
Diseaseachalasia (is_implicated_in)

VIPR1 AAAS

9.46e-0541182DOID:9164 (is_implicated_in)
DiseaseEndometrial Stromal Sarcoma

NUTM2A NUTM2B

1.57e-0451182C0206630
DiseaseClear cell sarcoma of kidney

NUTM2E NUTM2B

2.35e-0461182C0334488
Diseasehypopituitarism (implicated_via_orthology)

EIF2S3B EIF2S3

2.35e-0461182DOID:9406 (implicated_via_orthology)
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

CHD2 VARS2

3.29e-0471182DOID:0060475 (implicated_via_orthology)
Diseasehippocampal CA3 volume

MAP3K1 SLIT2 KANSL1

4.04e-04361183EFO_0009395
Diseaseirritable bowel syndrome (biomarker_via_orthology)

CRHR1 CRHR2

4.37e-0481182DOID:9778 (biomarker_via_orthology)
Diseaseleukodystrophy (implicated_via_orthology)

EIF2S3B EIF2S3

5.60e-0491182DOID:10579 (implicated_via_orthology)
Diseasevascular brain injury measurement, vascular brain injury

RASSF10 TRIL

1.20e-03131182EFO_0006791, EFO_0006800
DiseaseN-acetylglutamine measurement

IQCF1 RRP9

1.20e-03131182EFO_0800017
DiseaseCocaine-Related Disorders

CAMK2A CAMK2B CRHR1 CRHR2

1.27e-031171184C0236736
DiseaseCocaine Abuse

CAMK2A CAMK2B CRHR1 CRHR2

1.72e-031271184C0009171
DiseaseIntellectual Disability

CAMK2A CAMK2B KANSL1 EIF2S3 ATP1A1 PHIP TAT

2.18e-034471187C3714756
DiseaseAnorexia

CRHR1 CRHR2

2.33e-03181182C0003123
Diseasegestational age

FBXL12 VARS2 SLIT2 SDK1

2.33e-031381184EFO_0005112
DiseaseCocaine Dependence

CAMK2A CAMK2B CRHR1 CRHR2

2.39e-031391184C0600427
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

SLIT2 ZMYND10

2.59e-03191182DOID:9562 (implicated_via_orthology)
DiseaseOsteoarthritis of hip

HFE CRHR1

2.87e-03201182C0029410
DiseaseMajor Depressive Disorder

CAMK2A IRF7 CRHR1 EDEM1 ENPEP

2.99e-032431185C1269683
DiseaseUnipolar Depression

CAMK2A IRF7 CRHR1 EDEM1 ENPEP

3.92e-032591185C0041696

Protein segments in the cluster

PeptideGeneStartEntry
GRIANEWEEWRRRKE

EVI5L

91

Q96CN4
WRRAEGQAEWRAAQK

BTNL9

311

Q6UXG8
HHREQVWKRCINIWR

AAAS

71

Q9NRG9
ICRHLGRDWSWEKQK

ATG4A

91

Q8WYN0
RAWTVVRHDRLWTTR

CNTNAP1

621

P78357
RDWRWVLLRLHKAGA

APOBEC3D

141

Q96AK3
LREFHKWIERVVGWL

ANAPC2

286

Q9UJX6
VRVWSNIPAIRSRHW

DNMT3L

321

Q9UJW3
EHIRWNTKWRRAIPD

ASB4

346

Q9Y574
RLQWSRIWEVIGDHF

ARFGEF1

1181

Q9Y6D6
RIRLQWSRIWHVIGD

ARFGEF2

1126

Q9Y6D5
GSHAAAKRWLGRWRR

CENPVL1

46

A0A0U1RR11
IQNWWTRRKVRQEHG

ANO4

671

Q32M45
RHRWQGLVDTWKALK

CCDC180

341

Q9P1Z9
ARSKRWLKIIWRRHG

C22orf42

81

Q6IC83
DTWAAALRIQKVWRR

IQCA1

206

Q86XH1
ALVCRHLGRDWRWTQ

ATG4B

86

Q9Y4P1
HLGRDWRWTQRKRQP

ATG4B

91

Q9Y4P1
NKTRILRLWAAWGEE

RASSF10

106

A6NK89
QAWWRGTLVRRALLH

IQCF1

76

Q8N6M8
RLWRWHKSRLLQASE

PCDHGA11

716

Q9Y5H2
GWRLGWILIHDRRDI

TAT

286

P17735
GTRWISWRNRHGKQV

DDR2

126

Q16832
LEFRKSWERWRLEHL

GLP1R

411

P43220
SWERWRLEHLHIQRD

GLP1R

416

P43220
IHLLGLRVDWDDRWI

ATP1A1

881

P05023
PGIHAWQWSRELKLR

C9orf131

776

Q5VYM1
GHWLDKLRREWQMER

MPPE1

86

Q53F39
RQRFWRHWLVTDIKG

PEBP4

106

Q96S96
ILWGRIVNEWEDVRK

EVI5

136

O60447
EEHWQRHLARTTGRW

EVI5

536

O60447
GHWSIMKWNRERRRL

NDUFA13

46

Q9P0J0
RQHMRWLWDIGGRKS

FREM1

2096

Q5H8C1
HRWRLGKVLWEERNT

GCGR

416

P47871
RWQIWLAAERSRDQR

NRDE2

576

Q9H7Z3
LAAERSRDQRHWRPW

NRDE2

581

Q9H7Z3
VRSAVRKRWHRWQDH

CRHR2

366

Q13324
RHVPLRRRSEWKWAA

KANSL1

426

Q7Z3B3
RRRSEWKWAADRAAI

KANSL1

431

Q7Z3B3
DVGRRRKHQSWWQAL

EVC2

1181

Q86UK5
FEHNLETWRQLWRVL

GNL1

171

P36915
IEWLKQHRNTIREWF

ENPEP

936

Q07075
DARIFKAWAVARGRW

IRF7

56

Q92985
VWTLLHIRSAAERWK

OR6Q1

226

Q8NGQ2
RAWPTKLEWERHKIR

HFE

161

Q30201
REKRGPLWRHWRRET

PLA2G4F

26

Q68DD2
VLEDGRQWWKLRSRS

EPS8L2

521

Q9H6S3
RREDLDKLHRAAWWG

POTEB3

136

A0JP26
TVHWLREEAERGVLW

OBSCN

5401

Q5VST9
WVSNKWLHERGQEFR

P4HA1

511

P13674
RWQGWHSSERALERV

MYO15B

406

Q96JP2
EWARRWRQLVEKGPQ

PACSIN2

61

Q9UNF0
RGHSRWFWLVRVLLS

DUOXA2

46

Q1HG44
TDKREWWTGRLALDH

ESPL1

1771

Q14674
IWIRVASLNKGRWRH

KLHL24

386

Q6TFL4
GRQRKLWKDEGRWEH

CASC3

206

O15234
EKIMDWRPRHLTRWN

CC2D2A

1506

Q9P2K1
GSHAAAKRWLGRWRR

CENPVL2

46

P0DPI3
VSARDWLTRRNGKQW

FAHD2B

191

Q6P2I3
SDQEHIKLWRRNLWI

CHD2

1521

O14647
RHRKPTGQWRREWDA

CCDC9

281

Q9Y3X0
HSDRRILWITLRTWK

CCDC191

866

Q8NCU4
LGAQRERWETFRKLW

CENPVL3

96

A0A0U1RRI6
ARGRVAHLIEWKGWS

FAM131C

106

Q96AQ9
WHLGWTREFVEALRR

IFIH1

71

Q9BYX4
NSEVRSAIRKRWHRW

CRHR1

396

P34998
RWHRWQDKHSIRARV

CRHR1

406

P34998
EWVARRAVKALWNLR

EDEM1

326

Q92611
QAWWRGTLVRRTLLH

IQCF2

51

Q8IXL9
HKLTRDQWEDRIQVW

EZR

161

P15311
GVKHIARALRNVWQW

DCST2

176

Q5T1A1
KPFIDREWWHRTIQR

HLTF

606

Q14527
RVEKHWRLIGWGQIR

EIF2S3B

446

Q2VIR3
EEQRILNRSKRGWVW

CDH8

51

P55286
TEIQEKWHDSRRWQL

DDX21

691

Q9NR30
VRGNWQRWLKVRDLT

SDK1

1856

Q7Z5N4
RQAWEAGRTRKEEAW

CEP131

866

Q9UPN4
SEELKWWHERARLRS

INAVA

586

Q3KP66
RSHLRVKRGWVWNQF

CDH19

36

Q9H159
IRRKAGASWQDETRW

C4orf51

26

C9J302
ETRVWHRRDGKWLNV

CAMK2G

531

Q13555
ETRVWHRRDGKWQNV

CAMK2D

451

Q13557
VAEARTWHREGRWRV

PKD1

3916

P98161
TWHREGRWRVLRLGA

PKD1

3921

P98161
EGRRVSKAWLIRWSL

NYNRIN

1246

Q9P2P1
RELEIGVHWRDWRQL

PKN3

366

Q6P5Z2
VRREDLGKLHRAAWW

POTEA

61

Q6S8J7
RREDLDKLHRAAWWG

POTEC

136

B2RU33
AWKHEWLERRNRRGP

MAP3K1

196

Q13233
LEEGLWRAMREWQHT

NUTM2A

376

Q8IVF1
LEEGLWRAMREWQHT

NUTM2B

376

A6NNL0
LEEGLWRAMREWQHT

NUTM2E

376

B1AL46
TRNAAWRKRGWDENV

NIPSNAP1

246

Q9BPW8
RREDLDKLHRAAWWG

POTED

136

Q86YR6
VNKHWDVRIDSKAWR

RPUSD1

21

Q9UJJ7
LGRLVTRKSWLWQHD

MRPS34

76

P82930
LVRWHRMRGDQVLWV

VARS2

166

Q5ST30
QSEETRVWHRRDGKW

CAMK2B

636

Q13554
RVWHRRDGKWQNVHF

CAMK2B

641

Q13554
RVHIRDWREETLWKT

TRMT44

686

Q8IYL2
RWTQVRGWLRKLSAV

LMF2

386

Q9BU23
VQHRALELTGRWLLW

MOV10

456

Q9HCE1
RLVDDRWLWRHVDLT

FBXL12

36

Q9NXK8
VGHEVLRQRKNWWKD

GIN1

366

Q9NXP7
WRAAAALRLWGRVVE

SIRT3

6

Q9NTG7
RREDLDKLHRAAWWG

POTEI

136

P0CG38
GHRVWRAEGLRALWK

SLC25A43

56

Q8WUT9
ETRVWHRRDGKWQIV

CAMK2A

451

Q9UQM7
WLSADFAQERRWKRG

SRCAP

146

Q6ZRS2
GAWRRDIFGRIIWHK

MRPL47

166

Q9HD33
EPHWWTRKRFGIVRL

CHST15

286

Q7LFX5
DHVWWRRVPQRKEVS

SHFL

116

Q9NUL5
KLAREIRWRLWKAHE

ZNF503-AS2

161

A6NEH8
DRRTAEWVAWRLLGK

TXNDC16

286

Q9P2K2
QAELRRKWRRWHLQG

VIPR1

396

P32241
RNLLDAWRFWHKRAE

MIOS

701

Q9NXC5
DGTARIWQFKRREWK

PHIP

386

Q8WWQ0
GQEHRLGRWWRIKEA

RRP9

441

O43818
RWVRANHAAIWRIIL

PSTK

306

Q8IV42
RLRGLKRWMGDWHSQ

TRIL

366

Q7L0X0
DHWLRRREDSGWELK

THTPA

51

Q9BU02
THWRVAHERDELWRA

TRPV6

621

Q9H1D0
WHKLLGLWEARREAL

SPTBN4

1181

Q9H254
HLAWLSDWLRQRPRV

SLIT2

216

O94813
TPEKHRARKRQAWLW

TERF1

371

P54274
RLDTLIEWWREKNGS

TMEM168

521

Q9H0V1
RADPLRTWRWHNLLV

TLCD1

36

Q96CP7
LRRWKERETWEALAQ

SH2D4B

36

Q5SQS7
GHRRKNWTERWFVLK

SWAP70

221

Q9UH65
LHPAERKTQVWRWQS

ZNF365

66

Q70YC4
EIWERLERENRGKWQ

ZMYND10

336

O75800
QVRTLWHDPRNIGWK

THBS2

1091

P35442
NDRIWLAHRWRSRAE

ZSWIM1

236

Q9BR11
RREDLDKLHRAAWWG

POTEG

136

Q6S5H5
RREDLDKLHRAAWWG

POTEM

136

A6NI47
LHCWQIWKQRIRDLT

ZNF285

71

Q96NJ3
RRIEWLSLASRRIWG

VWA3A

491

A6NCI4
RVEKHWRLIGWGQIR

EIF2S3

446

P41091
GRHAAEGKWWVRKRI

LMF1

526

Q96S06
WTQDRLHDRQRVLHW

MXRA8

61

Q9BRK3
IALNRHRLWEMVGRW

GRIN2C

361

Q14957