Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZSCAN12 HIVEP2 ZSCAN5A SRF POU3F4 HNF4A FOXJ3 CLOCK ELL3 MEIS2 HSF5 IKZF5 ZSCAN5B TFCP2L1 ZFHX4 GLI3 NFYC NFAT5 FOXK1 ZFP62 TBX5 RAD23B	2.32e-05	1271	130	22	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZSCAN12 HIVEP2 ZSCAN5A SRF POU3F4 HNF4A FOXJ3 CLOCK MEIS2 HSF5 IKZF5 ZSCAN5B TFCP2L1 ZFHX4 GLI3 NFYC NFAT5 FOXK1 ZFP62 TBX5 RAD23B	5.25e-05	1244	130	21	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZSCAN12 HIVEP2 ZSCAN5A SRF POU3F4 HNF4A FOXJ3 CLOCK CREBBP MEIS2 HSF5 IKZF5 ZSCAN5B TFCP2L1 ZFHX4 GLI3 NFYC NFAT5 FOXK1 ZFP62 TBX5 RAD23B	1.78e-04	1459	130	22	GO:0000977
GeneOntologyMolecularFunction	chromatin binding	ASXL1 ERCC6 EP400 SRF SIN3A UPF1 HNF4A CLOCK CREBBP IKZF5 NCOA5 PRDM11 GLI3 NFAT5	3.31e-04	739	130	14	GO:0003682
GeneOntologyMolecularFunction	transcription factor binding	ASXL1 CRTC3 SRF HIPK2 TACC2 SIN3A HNF4A CLOCK CREBBP MEIS2 ARID2 NFAT5 TBX5 RAD23B	4.00e-04	753	130	14	GO:0008134
GeneOntologyMolecularFunction	DNA helicase activity	ERCC6 UPF1 ZRANB3 NAV2	7.14e-04	62	130	4	GO:0003678
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ASXL1 CRTC3 HIVEP2 ERCC6 SRF AKNA HIPK2 HNF4A FOXJ3 CLOCK CREBBP ELL3 MEIS2 KMT2C TFCP2L1 GLI3 ARID2 SS18L1 NFYC NFAT5 MAML3 ZFP62 TBX5	1.59e-05	1390	129	23	GO:0045944
GeneOntologyCellularComponent	chromatin	ERCC6 EP400 SRF POU3F4 SIN3A UPF1 HNF4A FOXJ3 CLOCK CREBBP MEIS2 TFCP2L1 ZFHX4 BRDT ARID2 SS18L1 NFYC BICRAL NFAT5 SAP130 FOXK1 TBX5	7.95e-05	1480	127	22	GO:0000785
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	ERCC6 EP400 ARID2 SS18L1 BICRAL	3.01e-04	96	127	5	GO:0070603
HumanPheno	Abnormal pupillary function	SH3TC2 ERCC6 KIF21A RPGR DNMBP ALK	2.49e-05	79	39	6	HP:0007686
HumanPheno	Miosis	ERCC6 KIF21A DNMBP ALK	4.54e-05	27	39	4	HP:0000616
HumanPheno	Y-shaped metatarsals	GLI3 TBX5	5.71e-05	2	39	2	HP:0010567
HumanPheno	Abnormal pupil morphology	SH3TC2 ERCC6 KIF21A SIN3A RPGR DNMBP ALK	6.24e-05	136	39	7	HP:0000615
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31C2 SPATA31C1 SPATA31A5	9.84e-09	12	126	5	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31C2 SPATA31C1 SPATA31A5	9.84e-09	12	126	5	IPR027970
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SEMA6C ZSCAN12 EP400 KIF21A AKNA SPG11 SIK3 FOXJ3 CLOCK URGCP KMT2C DST TECPR2 KLHL21 NAV2 DNMBP GARRE1	1.84e-11	529	131	17	14621295
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	CRTC3 UBQLN1 ANK3 EP400 BEAN1 UBR4 SIN3A TSC22D2 FOXJ3 ZRANB3 MAP4K1 ARID2 IGSF9B SAP130 ADGRL3	9.79e-11	430	131	15	35044719
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5	2.87e-09	6	131	4	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5	2.87e-09	6	131	4	25930072
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZSCAN12 ZSCAN5A SRF FOXJ3 CLOCK MEIS2 IKZF5 ZSCAN5B TFCP2L1 BRDT GLI3 ARID2 SLTM NFYC NFAT5 FOXK1 TBX5	1.12e-08	808	131	17	20412781
Pubmed	Human transcription factor protein interaction networks.	ASXL1 EP400 SEC24A UBR4 HIPK2 SIN3A UPF1 HNF4A CREBBP IKZF5 KMT2C DST ZFHX4 GLI3 PPIL3 ARID2 SS18L1 NFYC SAP130 PRRC2A GARRE1 FOXK1	1.94e-08	1429	131	22	35140242
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5 ADAMTS12	2.82e-08	24	131	5	32212159
Pubmed	A human MAP kinase interactome.	CRTC3 HIVEP2 ANK3 HIPK2 SIK3 CREBBP KMT2C DST ARID2 NFYC NAV2 BICRAL TNS1	4.29e-08	486	131	13	20936779
Pubmed	A census of human transcription factors: function, expression and evolution.	HIVEP2 SRF AKNA POU3F4 TSC22D2 HNF4A FOXJ3 CLOCK MEIS2 HSF5 TFCP2L1 ZFHX4 GLI3 NFYC NFAT5 FOXK1 TBX5	6.07e-08	908	131	17	19274049
Pubmed	Tagging genes with cassette-exchange sites.	FLNB UBR4 CREBBP DMXL1 NCOA5 KMT2C SLTM NAV2 RPGR FHIT TNS1	6.38e-08	335	131	11	15741177
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HIVEP2 SRF POU3F4 TACC2 HNF4A FOXJ3 CREBBP MEIS2 KMT2C TFCP2L1 GLI3 NFAT5 MAML3 FOXK1 TOP3A	8.10e-08	709	131	15	22988430
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	EP400 MAGI3 FOXJ3 DSCAML1 DST BICRAL NFAT5	6.58e-07	130	131	7	12421765
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CRTC3 HIVEP2 SEC24A MAGI3 PLEKHG2 SIK3 DST STARD9 MAP4K1 KIAA1217 NAV2 DNMBP GARRE1 FOXK1 TNS3	9.47e-07	861	131	15	36931259
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ROBO4 MXRA5 TNC UBR4 IGSF5 SIK3 CSMD2 FOXJ3 CREBBP ARID2 SS18L1 ARHGAP45 MAML3	9.48e-07	638	131	13	31182584
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERCC6 EP400 LGR4 SIN3A SIK3 CREBBP ELL3 ZFHX4 BRDT KLHL21 GLI3 ARID2 SS18L1 BICRAL SAP130 GARRE1 FOXK1	1.08e-06	1116	131	17	31753913
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZSCAN5A SRF POU3F4 HNF4A FOXJ3 CLOCK MEIS2 HSF5 TFCP2L1 GLI3 NFAT5 FOXK1	1.12e-06	544	131	12	28473536
Pubmed	Generation and analysis of 280,000 human expressed sequence tags.	SEC16B HIVEP2 SIK3 TSC22D2 CPS1 ADAMTS12 DST NAV2 DNMBP NFAT5	1.44e-06	368	131	10	8889549
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	EP400 HIPK2 TACC2 ZCCHC2 CREBBP PAPOLG ARID2 KIAA1217 DNMBP GARRE1 FOXK1 TOP3A	2.49e-06	588	131	12	38580884
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	UBR4 AKNA KMT2C DST STARD9 GLI3 CCDC17 TNS3	3.07e-06	233	131	8	37704626
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	UBQLN1 EP400 SIN3A UPF1 FOXJ3 CREBBP IKZF5 KMT2C PPIL3 ARID2 BICRAL SAP130 HNRNPLL PRRC2A FOXK1 RAD23B	4.28e-06	1103	131	16	34189442
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ZSCAN12 UFSP2 SIDT1 ZCCHC2 HNF4A ADAMTS12 TENM1 NAV2 IGSF9B TNS1 GARRE1	8.33e-06	552	131	11	10737800
Pubmed	Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.	SHC3 ALK	1.41e-05	2	131	2	12185581
Pubmed	MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity.	KMT2C TNS3	1.41e-05	2	131	2	33824309
Pubmed	Tensin Regulates Fundamental Biological Processes by Interacting with Integrins of Tonsil-Derived Mesenchymal Stem Cells.	TNS1 TNS3	1.41e-05	2	131	2	35954177
Pubmed	Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control.	FOXJ3 FOXK1	1.41e-05	2	131	2	22740631
Pubmed	CBP and SRF co-regulate dendritic growth and synaptic maturation.	SRF CREBBP	1.41e-05	2	131	2	30850733
Pubmed	Kv1.3 contains an alternative C-terminal ER exit motif and is recruited into COPII vesicles by Sec24a.	SEC24A KCNA3	1.41e-05	2	131	2	26156069
Pubmed	CREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expression.	HNF4A CREBBP	1.41e-05	2	131	2	10085149
Pubmed	Functional association between CBP and HNF4 in trans-activation.	HNF4A CREBBP	1.41e-05	2	131	2	9434765
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C HIVEP2 EP400 UBR4 AKNA DUS1L KMT2C DST KLHL21 NAV2 DNMBP FOXK1 TOP3A RASAL1 CD276	1.90e-05	1105	131	15	35748872
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	EP400 SRF CREBBP KMT2C ZFHX4 ARID2 NFYC BICRAL FOXK1	2.13e-05	398	131	9	35016035
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HIVEP2 POU3F4 SIN3A HNF4A CLOCK CREBBP MEIS2 PAPOLG NCOA5 TFCP2L1 GLI3 SS18L1 MAML3	2.87e-05	877	131	13	20211142
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	FLNB ASXL1 CREBBP DUS1L DST PRRC2A FOXK1 TNS3	3.96e-05	332	131	8	37433992
Pubmed	Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF.	SRF FOXK1	4.21e-05	3	131	2	17670796
Pubmed	Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.	HIPK2 CREBBP	4.21e-05	3	131	2	11740489
Pubmed	Sin3 interacts with Foxk1 and regulates myogenic progenitors.	SIN3A FOXK1	4.21e-05	3	131	2	22476904
Pubmed	Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair genes.	ERCC6 RAD23B	4.21e-05	3	131	2	19444904
Pubmed	Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB.	SRF CREBBP	4.21e-05	3	131	2	22649236
Pubmed	Acetylation regulates transcription factor activity at multiple levels.	HNF4A CREBBP	4.21e-05	3	131	2	10882110
Pubmed	PML-nuclear bodies are involved in cellular serum response.	SRF CREBBP	4.21e-05	3	131	2	12622724
Pubmed	The CREB-binding protein (CBP) cooperates with the serum response factor for transactivation of the c-fos serum response element.	SRF CREBBP	4.21e-05	3	131	2	9388250
Pubmed	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.	CREBBP SS18L1	4.21e-05	3	131	2	14716005
Pubmed	Mediator modulates Gli3-dependent Sonic hedgehog signaling.	CREBBP GLI3	4.21e-05	3	131	2	17000779
Pubmed	Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.	CREBBP GLI3	4.21e-05	3	131	2	10075717
Pubmed	Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.	EP400 CREBBP	4.21e-05	3	131	2	9590171
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	ASXL1 KMT2C FOXK1	5.68e-05	20	131	3	29785026
Pubmed	Interaction network of human early embryonic transcription factors.	HIVEP2 EP400 CREBBP KMT2C ZFHX4 ARID2 SS18L1 FOXK1	5.86e-05	351	131	8	38297188
Pubmed	Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia.	TNC MEIS2 GLI3	6.61e-05	21	131	3	23650387
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	LGR4 CPS1 HNF4A	6.61e-05	21	131	3	27088858
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	COL12A1 TNC ZSCAN5A LGR4 ZSCAN5B DST SLTM TNS1	7.40e-05	363	131	8	14691545
Pubmed	CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription.	CLOCK CREBBP	8.41e-05	4	131	2	19922678
Pubmed	Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.	ZSCAN5A ZSCAN5B	8.41e-05	4	131	2	31155506
Pubmed	Nuclear protein CBP is a coactivator for the transcription factor CREB.	CREBBP GLI3	8.41e-05	4	131	2	7913207
Pubmed	A proteomic approach identifies SAFB-like transcription modulator (SLTM) as a bidirectional regulator of GLI family zinc finger transcription factors.	GLI3 SLTM	8.41e-05	4	131	2	30782847
Pubmed	A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons.	SRF CREBBP	8.41e-05	4	131	2	16427017
Pubmed	High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk.	ERCC6 RAD23B	8.41e-05	4	131	2	17728339
Pubmed	Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc.	SHC3 KCNA3	8.41e-05	4	131	2	19166614
Pubmed	Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.	TNS1 TNS3	8.41e-05	4	131	2	19194507
Pubmed	Sumoylation controls CLOCK-BMAL1-mediated clock resetting via CBP recruitment in nuclear transcriptional foci.	CLOCK CREBBP	8.41e-05	4	131	2	26164627
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	CREBBP KMT2C	8.41e-05	4	131	2	28398509
Pubmed	Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.	SIN3A FOXK1	8.41e-05	4	131	2	25402684
Pubmed	Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1.	CLOCK CREBBP	8.41e-05	4	131	2	16606840
Pubmed	Vitamin A depletion is associated with low phosphoenolpyruvate carboxykinase mRNA levels during late fetal development and at birth in mice.	HNF4A CREBBP	8.41e-05	4	131	2	12840167
Pubmed	Binding and modulation of p53 by p300/CBP coactivators.	EP400 CREBBP	8.41e-05	4	131	2	9194565
Pubmed	ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.	ZSCAN5A ZSCAN5B	8.41e-05	4	131	2	27732952
Pubmed	Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes.	SRF TBX5	8.41e-05	4	131	2	15591049
Pubmed	Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice.	SRF HNF4A	8.41e-05	4	131	2	19205030
Pubmed	Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.	TNC HMCN1	8.41e-05	4	131	2	34504132
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	EP400 UBR4 CLOCK MEIS2 ZFHX4 GLI3 SAP130	1.01e-04	282	131	7	23667531
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CRTC3 ABCC4 COL12A1 UFSP2 ANK3 TNC CPS1 HNF4A KMT2C DST TECPR2 NFYC RPGR SAP130 CA6	1.12e-04	1293	131	15	15342556
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBQLN1 UBR4 PRRC2A RAD23B	1.16e-04	66	131	4	24811749
Pubmed	Inactivation of tensin3 in mice results in growth retardation and postnatal lethality.	TNS1 TNS3	1.40e-04	5	131	2	15733665
Pubmed	The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.	TNS1 TNS3	1.40e-04	5	131	2	17190795
Pubmed	Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.	FHIT ALK	1.40e-04	5	131	2	23991058
Pubmed	Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.	SEC16B PRRC2A	1.40e-04	5	131	2	23121087
Pubmed	The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.	SIN3A CREBBP	1.40e-04	5	131	2	10823891
Pubmed	Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor.	SRF TBX5	1.40e-04	5	131	2	30242271
Pubmed	Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages.	CRTC3 SIK3	1.40e-04	5	131	2	23033494
Pubmed	The effect of DNA repair defects on reproductive performance in nucleotide excision repair (NER) mouse models: an epidemiological approach.	ERCC6 RAD23B	1.40e-04	5	131	2	16315091
Pubmed	Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus.	CLOCK CREBBP	1.40e-04	5	131	2	25961797
Pubmed	RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP.	HNF4A CREBBP	1.40e-04	5	131	2	28128295
Pubmed	Hypoxic adaptation engages the CBP/CREST-induced coactivator complex of Creb-HIF-1α in transactivating murine neuroblastic glucose transporter.	CREBBP SS18L1	1.40e-04	5	131	2	23321477
Pubmed	Evaluation of genetic susceptibility loci for obesity in Chinese women.	SEC16B PRRC2A	1.40e-04	5	131	2	20616199
Pubmed	Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.	UBQLN1 RAD23B	1.40e-04	5	131	2	11827521
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB ABCC4 HIVEP2 ANK3 SRF HIPK2 MAGI3 FOXJ3 CREBBP KMT2C TECPR2 KIAA1217 IGSF9B NFAT5 SAP130 MAML3	1.58e-04	1489	131	16	28611215
Pubmed	A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification.	HNF4A GLI3 TBX5	1.78e-04	29	131	3	27320915
Pubmed	Multiple roles of mesenchymal beta-catenin during murine limb patterning.	COL12A1 MEIS2 TBX5	1.97e-04	30	131	3	16495310
Pubmed	The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3.	HIPK2 CREBBP	2.09e-04	6	131	2	16055500
Pubmed	14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).	CRTC3 SIK3	2.09e-04	6	131	2	29211348
Pubmed	Genetic analysis of the hypothalamic corticotropin-releasing factor system.	SHC3 CRHR1	2.09e-04	6	131	2	15705776
Pubmed	Circadian regulator CLOCK is a histone acetyltransferase.	CLOCK CREBBP	2.09e-04	6	131	2	16678094
Pubmed	A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis.	CREBBP MEIS2	2.09e-04	6	131	2	15161102
Pubmed	Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.	SIN3A CREBBP	2.09e-04	6	131	2	14761981
Pubmed	Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock.	CLOCK CREBBP	2.09e-04	6	131	2	20930143
Pubmed	Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study.	ERCC6 RAD23B	2.09e-04	6	131	2	16399771
Pubmed	Recruitment of Sprouty1 to immune synapse regulates T cell receptor signaling.	SPRY1 MAP4K1	2.09e-04	6	131	2	19915061
Pubmed	Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.	CLOCK TFCP2L1 ARID2 SAP130	2.10e-04	77	131	4	19505873
Pubmed	Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.	ABCC4 UBQLN1 RAD23B	2.17e-04	31	131	3	26222436
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ASXL1 SIK3 DSCAML1 KMT2C DST NAV2	2.19e-04	225	131	6	12168954
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	EP400 SIN3A KMT2C KIAA1217 SAP130	2.37e-04	146	131	5	23892456
Interaction	SMARCA4 interactions	ERCC6 EP400 SRF SIN3A UPF1 SIK3 HNF4A CREBBP TFCP2L1 KCNA3 BRDT GLI3 ARID2 SS18L1 BICRAL TBX5	3.56e-08	462	127	16	int:SMARCA4
Interaction	FHL2 interactions	EP400 SRF HIPK2 SIN3A PLEKHG2 CREBBP PRDM11 KIAA1217 NFYC NFAT5 SAP130 FOXK1	7.91e-06	396	127	12	int:FHL2
Interaction	PAX6 interactions	EP400 HIPK2 CREBBP MEIS2 KMT2C ZFHX4 ARID2 SS18L1 NFYC SAP130 FOXK1	2.07e-05	366	127	11	int:PAX6
Interaction	SP7 interactions	EP400 SIN3A CREBBP KMT2C ZFHX4 PPIL3 ARID2 SS18L1 SAP130 FOXK1	2.32e-05	304	127	10	int:SP7
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	2.24e-04	8	131	2	chr9q12
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ROBO4 MXRA5 IGSF5 DSCAML1 HMCN1 IGSF9B	7.92e-05	161	80	6	593
GeneFamily	Collagens\|Collagen proteoglycans	COL12A1 COL15A1	1.92e-04	5	80	2	575
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TNS1 TNS3	5.32e-04	8	80	2	837
GeneFamily	Fibronectin type III domain containing	ROBO4 COL12A1 TNC DSCAML1 IGSF9B	7.18e-04	160	80	5	555
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CLOCK CREBBP	2.52e-03	17	80	2	486
Coexpression	LAKE_ADULT_KIDNEY_C21_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_B	KIF21A LGR4 MAGI3 SIK3 RNF150 KMT2C TFCP2L1 FHIT	4.72e-08	103	130	8	M39240
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	FLNB ASXL1 HIVEP2 SEC24A SPG11 SIK3 TSC22D2 FOXJ3 CLOCK CREBBP MEIS2 UTP18 DST NFYC BICRAL RPGR DNMBP GARRE1 RAD23B	4.77e-08	856	130	19	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	FLNB HIVEP2 SEC24A FOXJ3 CLOCK CREBBP MEIS2 UTP18 DST NFYC RPGR DNMBP RAD23B	5.95e-07	466	130	13	M13522
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	ANK3 LGR4 SIK3 TSC22D2 RNF150 DST KIAA1217 NAV2 FHIT	1.01e-06	208	130	9	M39233
Coexpression	GSE13306_TREG_VS_TCONV_SPLEEN_UP	ASXL1 HIVEP2 SEC24A HIPK2 DSCAML1 STARD9 KIAA1217 ZC3H12D	7.32e-06	200	130	8	M3224
Coexpression	AIZARANI_LIVER_C10_MVECS_1	ROBO4 SPRY1 FLNB COL15A1 PALMD MEIS2 RPGR TNS1 GARRE1	8.25e-06	269	130	9	M39114
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	ABCC4 KIF21A HIPK2 LGR4 MAGI3 TFCP2L1 KIAA1217	1.12e-05	152	130	7	M39239
Coexpression	LAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET	HIVEP2 ANK3 MAGI3 SIK3 TSC22D2 KIAA1217 NFAT5 MAML3	2.73e-05	240	130	8	M39236
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	COL12A1 HIPK2 MEIS2 DST TNS1 MAML3 TNS3	2.99e-05	177	130	7	M39245
Coexpression	GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	CRTC3 UBQLN1 HSF5 ORMDL3 ZC3H12D IGSF9B FHIT	5.90e-05	197	130	7	M6512
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_MID_SCHWANN_CELL	COL15A1 ANK3 TNC IFITM2 STARD9 KANK4 TNS1 TNS3	5.96e-05	268	130	8	M45796
Coexpression	GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP	ABCC4 SRF ZCCHC2 CREBBP URGCP PAPOLG KLHL21	6.49e-05	200	130	7	M8042
Coexpression	GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_DN	HIPK2 LGR4 TACC2 UTP18 HNRNPLL GARRE1 RAD23B	6.49e-05	200	130	7	M6607
Coexpression	LAKE_ADULT_KIDNEY_C28_INTERSTITIUM	TNC MEIS2 DST KIAA1217 NAV2	7.01e-05	86	130	5	M39247
Coexpression	HAY_BONE_MARROW_STROMAL	SPRY1 MXRA5 COL12A1 TNC TACC2 PALMD MEIS2 ZFHX4 GLI3 KIAA1217 NAV2 TNS3 CD276	1.18e-04	767	130	13	M39209
Coexpression	LAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES	SIK3 MEIS2 DST TNS1 MAML3 ADGRL3	1.27e-04	155	130	6	M39246
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB COL12A1 PALMD MEIS2 KMT2C DST HMCN1 KIAA1217 GARRE1 ADGRL3	2.02e-11	200	131	11	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ASXL1 MXRA5 COL12A1 COL15A1 NCOA5 ADAMTS12 DNMBP GARRE1 TNS3	4.89e-09	188	131	9	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	MXRA5 COL12A1 COL15A1 TNC CSMD2 ADAMTS12 DST HMCN1 GLI3	7.35e-09	197	131	9	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB COL12A1 PALMD MEIS2 DST KIAA1217 GARRE1 ADGRL3	8.38e-09	200	131	9	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC MEIS2 RNF150 UTP18 KANK4 NAV2	2.00e-08	155	131	8	82e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC MEIS2 RNF150 UTP18 KANK4 NAV2	2.00e-08	155	131	8	979c1d53b435a82c57d16707eed8ba7346326866
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	FLNB COL12A1 ANK3 MAGI3 TACC2 DST NAV2 TNS1	4.10e-08	170	131	8	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 ELL3 MEIS2 ADAMTS12 GLI3 KIAA1217 NAV2	7.57e-08	184	131	8	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3 KIAA1217	9.69e-08	190	131	8	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3 KIAA1217	9.69e-08	190	131	8	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3 KIAA1217	1.01e-07	191	131	8	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3 KIAA1217	1.05e-07	192	131	8	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 ZFHX4 GLI3 KIAA1217 NAV2	1.05e-07	192	131	8	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MXRA5 COL12A1 COL15A1 CSMD2 ADAMTS12 HMCN1 ZFHX4 GLI3	1.05e-07	192	131	8	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3 KIAA1217	1.05e-07	192	131	8	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL12A1 COL15A1 TNC MEIS2 ADAMTS12 RNF150 ZFHX4 NAV2	1.18e-07	195	131	8	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 LGR4 MAGI3 TACC2 TFCP2L1 ZFHX4 FHIT RASAL1	1.23e-07	196	131	8	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1 ADGRL3	1.44e-07	200	131	8	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1 ADGRL3	1.44e-07	200	131	8	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1 ADGRL3	1.44e-07	200	131	8	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1 ADGRL3	1.44e-07	200	131	8	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	ABCC4 ANK3 MAGI3 TACC2 SHC3 TFCP2L1 KIAA1217	5.51e-07	163	131	7	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 DST GLI3 KIAA1217 RPGR ALK ADGRL3	6.75e-07	168	131	7	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	ZRANB3 MEIS2 HSF5 DST ARID2 IGSF9B NFAT5	9.59e-07	177	131	7	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ASXL1 COL12A1 HIVEP2 NCOA5 HMCN1 GARRE1 TNS3	9.95e-07	178	131	7	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CPS1 DSCAML1 HMCN1 ZFHX4 TENM1 ADGRL3	1.24e-06	184	131	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CPS1 DSCAML1 HMCN1 ZFHX4 TENM1 ADGRL3	1.24e-06	184	131	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CPS1 DSCAML1 HMCN1 ZFHX4 TENM1 ADGRL3	1.24e-06	184	131	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL12A1 COL15A1 MEIS2 ADAMTS12 ZFHX4 NAV2 TNS1	1.38e-06	187	131	7	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 TACC2 TSC22D2 SHC3 RNF150 TFCP2L1 HMCN1	1.43e-06	188	131	7	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 TACC2 TSC22D2 SHC3 RNF150 TFCP2L1 HMCN1	1.43e-06	188	131	7	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ASXL1 ANK3 KIF21A SIDT1 AKNA TACC2 FGFBP2	1.43e-06	188	131	7	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 TSC22D2 SHC3 RNF150 TFCP2L1 HMCN1 NAV2	1.49e-06	189	131	7	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	ASK428-Epithelial-Transformed_epithelium\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	SH3TC2 MXRA5 BEAN1 CPS1 ZFHX4 GLI3 TBX5	1.49e-06	189	131	7	87189275234b5d59484c58acbb14a09903f2b578
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 TSC22D2 SHC3 RNF150 TFCP2L1 HMCN1 NAV2	1.49e-06	189	131	7	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 GLI3 KIAA1217 NAV2	1.59e-06	191	131	7	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ROBO4 SPRY1 HIPK2 MEIS2 KIAA1217 RPGR TNS1	1.59e-06	191	131	7	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 GLI3 KIAA1217 NAV2	1.59e-06	191	131	7	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 ZFHX4 GLI3 KIAA1217	1.65e-06	192	131	7	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	TNC ADAMTS12 DST HMCN1 NAV2 MAML3 TNS3	1.65e-06	192	131	7	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	FLNB ASXL1 KIF21A LGR4 MAGI3 HNF4A ZRANB3	1.71e-06	193	131	7	503a979328c68b096680b71359a26f02fafdff35
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB IFITM2 PALMD MEIS2 DST HMCN1 GARRE1	1.71e-06	193	131	7	58c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 ZFHX4 NAV2 ADGRL3	1.77e-06	194	131	7	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB PALMD MEIS2 DST HMCN1 KIAA1217 ADGRL3	1.77e-06	194	131	7	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 TNC MEIS2 ADAMTS12 DST GLI3 KIAA1217	1.77e-06	194	131	7	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 ZFHX4 KIAA1217 NAV2	1.77e-06	194	131	7	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 TNC MEIS2 ADAMTS12 DST GLI3 KIAA1217	1.77e-06	194	131	7	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 COL12A1 TNC KIF21A ZFHX4 GLI3 KANK4	1.83e-06	195	131	7	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 KIAA1217	1.83e-06	195	131	7	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 LGR4 TSC22D2 SHC3 RNF150 TFCP2L1 HMCN1	1.83e-06	195	131	7	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 KIAA1217	1.83e-06	195	131	7	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3	1.89e-06	196	131	7	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3	1.89e-06	196	131	7	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 TNC MEIS2 ADAMTS12 RNF150 NAV2 TNS3	1.96e-06	197	131	7	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 TNC SHC3 MEIS2 ADAMTS12 GLI3	1.96e-06	197	131	7	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 TNC MEIS2 ADAMTS12 RNF150 NAV2 TNS3	1.96e-06	197	131	7	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPRY1 TNC ADAMTS12 DST HMCN1 GLI3 TBX5	2.02e-06	198	131	7	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	367C-Endothelial_cells\|367C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 SPRY1 FLNB PALMD MEIS2 RPGR GARRE1	2.09e-06	199	131	7	636ff80938907f137e955388797072ab45289062
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	SPRY1 TNC ADAMTS12 DST HMCN1 GLI3 TBX5	2.09e-06	199	131	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNB MXRA5 COL12A1 COL15A1 TNC DST ADGRL3	2.09e-06	199	131	7	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPRY1 MXRA5 TNC ADAMTS12 DST HMCN1 TBX5	2.09e-06	199	131	7	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPRY1 MXRA5 TNC ADAMTS12 DST HMCN1 TBX5	2.09e-06	199	131	7	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	367C-Endothelial_cells-Endothelial-A_(Artery)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 SPRY1 FLNB PALMD MEIS2 RPGR GARRE1	2.09e-06	199	131	7	29ed081bd5204a32068b420f2244f3704891547b
ToppCell	367C-Endothelial_cells-Endothelial-A_(Artery)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ROBO4 SPRY1 FLNB PALMD MEIS2 RPGR GARRE1	2.09e-06	199	131	7	c2d85f80037f209a4a329790f475d9f98f590262
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	COL12A1 COL15A1 TNC MEIS2 ADAMTS12 DST NAV2	2.09e-06	199	131	7	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 KIAA1217 GARRE1 ADGRL3	2.16e-06	200	131	7	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1	2.16e-06	200	131	7	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB COL12A1 PALMD MEIS2 KIAA1217 GARRE1	2.16e-06	200	131	7	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ROBO4 SPRY1 FLNB COL15A1 PALMD RPGR GARRE1	2.16e-06	200	131	7	27507c4b41d45c7cc50e4993169c0302be22ee34
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL12A1 COL15A1 HMCN1 STARD9 TENM1 NAV2 TBX5	2.16e-06	200	131	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 KIAA1217 GARRE1 ADGRL3	2.16e-06	200	131	7	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1	2.16e-06	200	131	7	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 KIAA1217 GARRE1 ADGRL3	2.16e-06	200	131	7	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1	2.16e-06	200	131	7	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Endothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ROBO4 SPRY1 FLNB COL15A1 PALMD RPGR GARRE1	2.16e-06	200	131	7	b65fb8d378abd91cdabf5faac5f4b90d527f8c44
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ROBO4 SPRY1 FLNB COL15A1 PALMD RPGR GARRE1	2.16e-06	200	131	7	2cb6e35add34b9dc564ebcf5d3cbc761325ca9f4
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ROBO4 FLNB PALMD MEIS2 DST KIAA1217 GARRE1	2.16e-06	200	131	7	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPRY1 MXRA5 COL15A1 HMCN1 TENM1 NAV2 TBX5	2.16e-06	200	131	7	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	ABCC4 ANK3 MAGI3 TACC2 SHC3 TFCP2L1	7.16e-06	157	131	6	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 MAGI3 TACC2 TFCP2L1 KIAA1217 NAV2	8.56e-06	162	131	6	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS9 ELL3 MEIS2 IGSF9B RPGR TBX5	1.05e-05	168	131	6	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS9 ELL3 MEIS2 IGSF9B RPGR TBX5	1.05e-05	168	131	6	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 COL12A1 TNC POU3F4 ADAMTS12 TENM1	1.09e-05	169	131	6	1d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 COL12A1 TNC POU3F4 ADAMTS12 TENM1	1.09e-05	169	131	6	58098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF21A AKNA HIPK2 RGS9 FGFBP2 TENM1	1.20e-05	172	131	6	86f52f486d67217fc1b8443ab362c975df2974a4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF21A AKNA HIPK2 RGS9 FGFBP2 TENM1	1.20e-05	172	131	6	fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF21A AKNA HIPK2 RGS9 FGFBP2 TENM1	1.20e-05	172	131	6	e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 SIDT1 MAP4K1 IGSF9B ADGRL3 TBX5	1.29e-05	174	131	6	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-E\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ROBO4 HIPK2 IFITM2 MEIS2 KIAA1217 ADGRL3	1.29e-05	174	131	6	4a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL12A1 DST HMCN1 NAV2 TNS1 TBX5	1.33e-05	175	131	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPG11 DSCAML1 HSF5 PAPOLG RPGR RASAL1	1.33e-05	175	131	6	91cb819a1786020713b7e64480de0545380daae9
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 COL15A1 DSCAML1 CRHR1 TENM1 NAV2	1.33e-05	175	131	6	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	ZRANB3 HSF5 DST ARID2 IGSF9B NFAT5	1.37e-05	176	131	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	SPRY1 MXRA5 DST HMCN1 KANK4 TBX5	1.42e-05	177	131	6	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SPRY1 MXRA5 DST HMCN1 KANK4 TBX5	1.42e-05	177	131	6	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 SHC3 TFCP2L1 HMCN1 TENM1 NAV2	1.42e-05	177	131	6	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCC4 ANK3 MAGI3 TACC2 SHC3 KIAA1217	1.46e-05	178	131	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 MEIS2 ADAMTS12 ZFHX4 KIAA1217	1.46e-05	178	131	6	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC4 MXRA5 TNC ADAMTS12 ALK ADGRL3	1.51e-05	179	131	6	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MXRA5 COL12A1 COL15A1 TNC ADAMTS12 HMCN1	1.56e-05	180	131	6	935c091bbcd6d10b81dc4731779e5bd98205c99f
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ASXL1 SH3TC2 ZSCAN12 HIVEP2 HIPK2 VPS26C PALMD NFYC BICRAL	5.81e-07	175	126	9	5908_DN
Drug	Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; HL60; HT_HG-U133A	ABCC4 ERCC6 ZSCAN5A TSC22D2 ZCCHC2 CPS1 CREBBP PAPOLG DNMBP	1.26e-06	192	126	9	2919_DN
Drug	Methylene Chloride	ZSCAN12 HIVEP2 ZCCHC2 CLOCK ZFHX4 NFAT5 HNRNPLL ZFP62	3.57e-06	163	126	8	ctd:D008752
Drug	irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A	HIVEP2 LGR4 TACC2 MEIS2 ZFHX4 GLI3 NAV2 TNS3	5.08e-06	171	126	8	7535_DN
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A	SPRY1 FLNB SIDT1 FHIT TNS1 PRRC2A ADGRL3 RAD23B	1.38e-05	196	126	8	1864_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA	ASXL1 ABCC4 SEC24A SIDT1 TACC2 UPF1 BICRAL TOP3A	1.38e-05	196	126	8	1082_UP
Disease	longitudinal alcohol consumption measurement	SPATA31C2 SPATA31C1 IGSF9B	6.12e-06	9	125	3	EFO_0007645
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	SPG11 SIK3 CPS1 HNF4A	1.91e-04	67	125	4	EFO_0008595, EFO_0020946
Disease	beta-1,4-galactosyltransferase 7 measurement	SIK3 FAM153A	2.64e-04	6	125	2	EFO_0802314
Disease	renal overload-type gout	SPATA31C2 SPATA31C1	2.64e-04	6	125	2	EFO_0021525
Disease	Age related macular degeneration	ERCC6 HMCN1 RPGR	2.77e-04	30	125	3	C0242383
Disease	Asperger syndrome	SLTM FHIT	3.69e-04	7	125	2	EFO_0003757
Disease	eosinophil cationic protein measurement	SPATA31C2 SPATA31C1	4.90e-04	8	125	2	EFO_0010913
Disease	Attached earlobe	HIVEP2 KIAA1217	4.90e-04	8	125	2	HP_0009907
Disease	major depressive disorder	CELF4 ZSCAN12 HIVEP2 NCOA5 FHIT	5.30e-04	155	125	5	MONDO_0002009
Disease	cortical surface area measurement	SPRY1 FLNB ANK3 SIDT1 HIPK2 TSC22D2 CPS1 CRHR1 MEIS2 GLI3 RP1L1 NAV2 TNS1 PRRC2A RAD23B	5.80e-04	1345	125	15	EFO_0010736
Disease	X-21467 measurement	CPS1 DNMBP	6.29e-04	9	125	2	EFO_0020007
Disease	neutrophil count	SEMA6C FLNB HIVEP2 MAGI3 IFITM2 PLEKHG2 SIK3 ZCCHC2 CPS1 HNF4A CREBBP ZRANB3 RP1L1 ARHGAP45 TNS3	7.65e-04	1382	125	15	EFO_0004833
Disease	immunoglobulin isotype switching measurement	UBR4 PAPOLG ARHGAP45	8.66e-04	44	125	3	EFO_0010128
Disease	cortical thickness	FLNB COL12A1 SIDT1 LGR4 TACC2 TSC22D2 CLOCK CRHR1 GLI3 NAV2 FHIT TNS1 RAD23B	9.01e-04	1113	125	13	EFO_0004840
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	SEC16B TSC22D2 KLHL21 FHIT NFAT5 PRRC2A MAML3	9.43e-04	364	125	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	argininosuccinate measurement	ABCC4 ALK	9.55e-04	11	125	2	EFO_0010461
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	SPG11 SIK3 CPS1 HNF4A	9.82e-04	103	125	4	EFO_0008595, EFO_0020944
Disease	heart rate variability measurement, response to antipsychotic drug	COL12A1 NAV2 SAP130	9.86e-04	46	125	3	EFO_0008003, GO_0097332
Disease	response to xenobiotic stimulus	CELF4 UBR4 CSMD2 MEIS2 FHIT	1.09e-03	182	125	5	GO_0009410
Disease	free androgen index	AKNA SIN3A CPS1 HNF4A ZFHX4 FHIT DNMBP	1.10e-03	374	125	7	EFO_0007005
Disease	cleft palate (is_implicated_in)	FLNB MEIS2	1.14e-03	12	125	2	DOID:674 (is_implicated_in)
Disease	body fat percentage	SEC16B TSC22D2 KLHL21 IGSF9B FHIT NFAT5 PRRC2A MAML3	1.15e-03	488	125	8	EFO_0007800
Disease	Prostatic Neoplasms	ABCC4 COL15A1 IGSF5 CREBBP KMT2C ARID2 FHIT CD276 RAD23B	1.27e-03	616	125	9	C0033578
Disease	Malignant neoplasm of prostate	ABCC4 COL15A1 IGSF5 CREBBP KMT2C ARID2 FHIT CD276 RAD23B	1.27e-03	616	125	9	C0376358
Disease	egg allergy measurement, parental genotype effect measurement	SPATA31C2 SPATA31C1	1.35e-03	13	125	2	EFO_0005939, EFO_0007018
Disease	Fetal Alcohol Spectrum Disorders	ANK3 SRF	1.35e-03	13	125	2	C2985290
Disease	Diffuse Large B-Cell Lymphoma	CREBBP PRDM11 ALK	1.66e-03	55	125	3	C0079744
Disease	myelodysplastic syndrome (implicated_via_orthology)	ASXL1 CREBBP	1.80e-03	15	125	2	DOID:0050908 (implicated_via_orthology)
Disease	urate measurement, spine bone mineral density	SH3TC2 NAV2 FHIT	1.93e-03	58	125	3	EFO_0004531, EFO_0007701
Disease	amygdala volume change measurement	SPATA31C2 SPATA31C1	2.05e-03	16	125	2	EFO_0021490
Disease	waist-hip ratio	SEC16B COL15A1 ANK3 LGR4 SIK3 TSC22D2 CLOCK CRHR1 MEIS2 UTP18 GLI3 NFAT5 MAML3	2.13e-03	1226	125	13	EFO_0004343
Disease	FEV/FEC ratio	ASXL1 HIVEP2 COL15A1 IFITM2 DST HMCN1 BRDT NAV2 CCDC17 TNS1 CD276 TBX5 RAD23B	2.16e-03	1228	125	13	EFO_0004713
Disease	mood instability measurement	CELF4 HIVEP2 NCOA5 FOXK1	2.18e-03	128	125	4	EFO_0008475
Disease	proprotein convertase subtilisin/kexin type 7 measurement	SIK3 DSCAML1	2.32e-03	17	125	2	EFO_0008270
Disease	Fetal Alcohol Syndrome	ANK3 SRF	2.32e-03	17	125	2	C0015923
Disease	waist circumference	SEC16B TSC22D2 RNF150 NAV2 FHIT NFAT5 PRRC2A	2.40e-03	429	125	7	EFO_0004342
Disease	Age-related macular degeneration	ERCC6 HMCN1	2.61e-03	18	125	2	cv:C0242383
Disease	squamous cell carcinoma (is_implicated_in)	KMT2C FHIT	2.61e-03	18	125	2	DOID:1749 (is_implicated_in)
Disease	smoking cessation	ASXL1 CELF4 ANK3 KIAA1217 NFAT5 MAML3	2.67e-03	325	125	6	EFO_0004319
Disease	Osteoarthritis of hip	TNC CRHR1	3.22e-03	20	125	2	C0029410
Disease	serum homoarginine measurement	CPS1 TNS1	3.22e-03	20	125	2	EFO_0005421
Disease	citrulline measurement	CPS1 RP1L1	3.22e-03	20	125	2	EFO_0009777
Disease	apolipoprotein A 1 measurement	AKNA SPG11 SIK3 TSC22D2 CPS1 HNF4A ZRANB3 KANK4 CCDC17 FOXK1	3.32e-03	848	125	10	EFO_0004614
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	SPG11 SIK3 CPS1 HNF4A	3.34e-03	144	125	4	EFO_0004611, EFO_0020943
Disease	Manic Disorder	ANK3 ZCCHC2 STARD9	3.44e-03	71	125	3	C0024713
Disease	attention function measurement	CSMD2 DST KIAA1217 ALK	3.68e-03	148	125	4	EFO_0007636
Disease	age at menarche	SEMA6C SEC16B FOXJ3 DSCAML1 DST ZFHX4 FHIT NFAT5	3.87e-03	594	125	8	EFO_0004703

Protein segments in the cluster

Peptide	Gene	Start	Entry
VMQTVSQAGAVHGAL	EP400	1676	Q96L91
AAGQTVVAQPVHMQQ	EP400	2951	Q96L91
GHPTQEMTFGAQASV	CCDC17	36	Q96LX7
PGAEQTGIQNKTQMH	CDY2A	191	Q9Y6F7
NQGQSLPGSSREHMA	ELL3	171	Q9HB65
LTQVGVSQGHNMCPD	CSMD2	331	Q7Z408
EQLSNGITVMHPSGD	BRDT	766	Q58F21
TSVMDTLPLNGNHGN	ADGRL3	1191	Q9HAR2
NLTATQMSFPVQGVH	ARID2	661	Q68CP9
QMSFPVQGVHTVAQT	ARID2	666	Q68CP9
ETLTQVSPQMTGHAG	CREBBP	241	Q92793
VSPQMTGHAGLNTAQ	CREBBP	246	Q92793
VQGVMSAEGNLHNPA	DUS1L	226	Q6P1R4
GPQAQGLVMEAATHS	DNMBP	526	Q6XZF7
QQDAHGSVTITGQPM	CD276	446	Q5ZPR3
GEFPMVNNGHTVQIS	CA6	76	P23280
VNNGHTVQISLPSTM	CA6	81	P23280
MNLHQVLTGAVNPGD	DMXL1	1	Q9Y485
TGVMQIETGPANHIF	DMXL1	2981	Q9Y485
MPNEGIPHSSQTQEQ	ERCC6	1	Q03468
PLNGEHTQAGTAMSR	ASXL1	701	Q8IXJ9
NMVTGLFHNPSIGNA	ADAMTS12	276	P58397
QLPHVMQVVTQDGTG	RASAL1	631	O95294
EAGSGHMNYIQVTPQ	RAD23B	351	P54727
AANTVDITQPGQHMA	RGS9	461	O75916
HSNQHMNTVDQPLGV	INSYN2A	176	Q6ZSG2
NPSGSVVMVSGLHQL	HNRNPLL	331	Q8WVV9
MPNEGIPHSSQTQEQ	ERCC6	1	P0DP91
TNGLGIGVNESIHNM	PALMD	291	Q9NP74
VGAATGAHSQMQLVQ	IGHV1-58	11	A0A0C4DH39
GAHSQMQLVQSGPEV	IGHV1-58	16	A0A0C4DH39
GQQMLGQISATSHIN	GLI3	1341	P10071
PMHSQGQQFSGVSQL	KMT2C	2341	Q8NEZ4
TSVTGQVLGGPHNLM	HIPK2	101	Q9H2X6
GHSMVQAVGTLQTQT	ARHGAP45	351	Q92619
MGQSQANHIPGDRSA	MAGI3	961	Q5TCQ9
GQSMLVNSAITQQHP	MAML3	916	Q96JK9
MNHIVQTFSPVNSGQ	IFITM2	1	Q01629
SQGPVGMETETINQQ	DST	5306	Q03001
NSVDPNVGGQVMDIH	MEIS2	461	O14770
NVIVANTMPTHLSNG	HNF4A	401	P41235
NGNHVANSPVSIMVV	FLNB	1981	O75369
HLVSQTTAQMGQPQA	NCOA5	556	Q9HCD5
VPGQTVSEEATGVHM	FAM153A	186	Q9UHL3
GPQAHMQQVTSSLKG	FGFBP2	121	Q9BYJ0
VIEEGGMNHSAFPQT	KCNA3	531	P22001
ASMVQQFPNLTGTVH	LGR4	306	Q9BXB1
QQTHHVNMISGSVSG	IKZF5	21	Q9H5V7
QPQATLFHNTAGGTM	NFAT5	1416	O94916
GQTTPVTMQVGEGQQ	NFYC	186	Q13952
SLVHADSAGMQQGSP	POU3F4	16	P49335
LQVHVAPSISGSNNM	HMCN1	2006	Q96RW7
GHTDHMVTNTSNGQP	ABCC4	1301	O15439
QGQPHLNGMSNITKT	PAPOLG	626	Q9BWT3
FQTHDQIGMISAGPS	UPF1	971	Q92900
MGVHTGDSVVVAPAQ	CPS1	656	P31327
SMQDGPEAGQTVKHV	FHIT	81	P49789
GGNFTSEMIIHNVEP	IGSF5	101	Q9NSI5
PSMNQVHVGGSLAVL	KLHL21	496	Q9UJP4
QGSVVGPHMSVNIVN	BICRAL	351	Q6AI39
MTAGSRQHALSVGPQ	COL12A1	371	Q99715
TISHMNVTGPQIRDG	DSCAML1	466	Q8TD84
GSNSVAQVSLSHPQM	FOXJ3	361	Q9UPW0
HFGSMSVGNSVNNIP	CRTC3	296	Q6UUV7
SVGNSVNNIPAAMTH	CRTC3	301	Q6UUV7
FNMGQSHQGSPLVTR	GARRE1	656	O15063
QTVASQMAPGVPGHT	FOXK1	586	P85037
QPNHSIHTGMVPQGT	AKNA	481	Q7Z591
QMPGHAEVALVNGSI	ANK3	1706	Q12955
VQLTMSPEVHQSNVG	CRHR1	201	P34998
TQGQTDVMVNTDPVH	KANK4	406	Q5T7N3
EQRTPAQGGLHTVSM	BEAN1	196	Q3B7T3
NMSIIQHSSPKQGSG	COL15A1	306	P39059
GQDLQHISNQKMPTG	DRICH1	56	Q6PGQ1
MNVGTAHSEVNPNTR	ORMDL3	1	Q8N138
FNVGSNTNETITMPH	RNF150	146	Q9ULK6
GEMSTEHRGPVQVTQ	MAP4K1	701	Q92918
QHVSQGIFMTQPATT	RPGR	561	Q92834
VHVQQGPQTMVSSSQ	HSF5	276	Q4G112
SVQFHPGAQIVMVAG	UTP18	256	Q9Y5J1
ASQVPQGHLQSMPTG	SPATA31C2	896	B4DYI2
VVVVASMQGAHGPES	TSC22D2	226	O75157
GSPQLGEGMFQHQTS	TBX5	446	Q99593
EGITSNTNNGSMVVH	SEC24A	246	O95486
TTMTHGVQNIGQTQG	PRDM11	381	Q9NQV5
SQVPQGHLQSMPTGN	SPATA31A7	1051	Q8IWB4
VVISNPHATMTQQGN	NAV2	1346	Q8IVL1
SQISGGAMDSQLHPN	PRRC2A	1846	P48634
AGMITQHSSNASPIN	SLTM	991	Q9NWH9
TNPGSFVLTGMHNGQ	SHC3	526	Q92529
QMQEQGKGNLHVTSP	KIAA1217	21	Q5T5P2
TNDMVNVTTPGQVHQ	SIN3A	196	Q96ST3
MIQPHGAASSSQFQG	SIK3	756	Q9Y2K2
PVISTIMGNGHQRSV	TENM1	1166	Q9UKZ4
ASVQQHGIQSAQGMS	SH3TC2	691	Q8TF17
GAMEVNSIGNHPQVQ	STARD9	2131	Q9P2P6
PQGHLQSTPTGNMQA	SPATA31C1	906	P0DKV0
IPTHMNALGSQANGS	TNS3	716	Q68CZ2
GPTGIHVVVSNEMVQ	TFCP2L1	436	Q9NZI6
SGQKEVHGMAQPSQN	SDF2	171	Q99470
MQVSHSQVQEPGGVP	SRF	441	P11831
GEQTQLEIATHMPGS	ROBO4	401	Q8WZ75
VEGGHVNMAFSQSNP	ALK	1471	Q9UM73
QAAINALHGSQTMPG	CELF4	206	Q9BZC1
VVPTNQIQSGMNTGH	CLOCK	601	O15516
QIQSGMNTGHIGTTQ	CLOCK	606	O15516
GQIGNGPSHVSMQQT	SS18L1	121	O75177
LANHFQSEGTPVMIG	UFSP2	386	Q9NUQ7
ANGLVHDPVMGSQAN	ZCCHC2	1081	Q9C0B9
QGTGHKQMFNPTEES	SPG11	2066	Q96JI7
SQVPQGHLQSMPTGN	SPATA31A3	1051	Q5VYP0
RMQQNGHDPSSGVQE	URGCP	536	Q8TCY9
HSIAANVNSPGQGML	ZFHX4	1591	Q86UP3
MGQEHTQAQPTQGAA	RP1L1	1486	Q8IWN7
SQVPQGHLQSMPTGN	SPATA31A5	1051	Q5VU36
SQGQLRHTSQGMGIP	IGSF9B	1131	Q9UPX0
TGQEIMSLGGHPNNV	KIF21A	1376	Q7Z4S6
SNDGSGNMVASHPIA	SIDT1	346	Q9NXL6
HNVRGVVSMANNGPN	PPIL3	81	Q9H2H8
GTTEPGHQQFIQQML	UBQLN1	516	Q9UMX0
ASSVNQMHPGTGQAR	ZSCAN5B	166	A6NJL1
QTGVGVASTVHLNPM	SAP130	531	Q9H0E3
IQGMEHLENGPSVSV	TNS1	311	Q9HBL0
EVMVSGFTQGHQTKP	TNC	1596	P24821
ASSVNQMRPGEGQAH	ZSCAN5A	166	Q9BUG6
NRESPGQAGMNSIHS	ZSCAN5A	321	Q9BUG6
VAVDGMAGPHSNITV	SEMA6C	426	Q9H3T2
MDPQNQHGSGSSLVV	SPRY1	1	O43609
ALDTIDVQGHPQTGM	TACC2	366	O95359
GVSLVSVHSSPNDQM	TECPR2	1266	O15040
EMLQTHLGPGENTVS	SEC16B	826	Q96JE7
QGSHFQPSTVEMVDG	TOP3A	496	Q13472
PIVIDGSNVAMSHGN	ZC3H12D	91	A2A288
ITHQTMPIGQRGSEQ	ZFP62	101	Q8NB50
STQESMGLHRAQGAP	PLEKHG2	1366	Q9H7P9
MSTFGSHEGQRQPQI	HIVEP2	36	P31629
MQSSGIPNGGHIRQE	UBR4	2741	Q5T4S7
PGEQVSVHTGEQEMF	ZSCAN12	131	O43309
HQGVSLTMEGTVNLQ	VPS26C	36	O14972
TPQGSAVMQIDSLNH	ZRANB3	646	Q5FWF4
ATPVNNEGTQHMSGP	MXRA5	1541	Q9NR99
NEGTQHMSGPNELST	MXRA5	1546	Q9NR99