Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessERAD pathway

SEL1L HERPUD1 UBXN6

1.43e-04119183GO:0036503
GeneOntologyBiologicalProcesssynaptic vesicle clustering

SYN3 SYN1

1.64e-0422182GO:0097091
GeneOntologyBiologicalProcessretrograde protein transport, ER to cytosol

SEL1L HERPUD1

2.88e-0429182GO:0030970
GeneOntologyBiologicalProcessendoplasmic reticulum to cytosol transport

SEL1L HERPUD1

2.88e-0429182GO:1903513
GeneOntologyBiologicalProcessprotein exit from endoplasmic reticulum

SEL1L HERPUD1

8.94e-0451182GO:0032527
GeneOntologyBiologicalProcesssynaptic vesicle localization

SYN3 SYN1

1.72e-0371182GO:0097479
GeneOntologyCellularComponentextrinsic component of synaptic vesicle membrane

SYN3 SYN1

2.08e-0425182GO:0098850
GeneOntologyCellularComponentextrinsic component of organelle membrane

SYN3 SYN1

6.19e-0443182GO:0031312
MousePhenoimpaired social transmission of food preference

SYN3 SYN1

5.10e-0511142MP:0002969
MousePhenoincreased synaptic depression

SYN3 SYN1

7.22e-0513142MP:0002916
MousePhenoimpaired discrimination learning

SYN3 SYN1

8.42e-0514142MP:0012296
MousePhenoabnormal discrimination learning

SYN3 SYN1

3.72e-0429142MP:0002802
DomainSynapsin_pre-ATP-grasp_dom

SYN3 SYN1

2.34e-063172IPR020897
DomainSynapsin_ATP-bd_dom

SYN3 SYN1

2.34e-063172IPR020898
DomainSynapsin_C

SYN3 SYN1

2.34e-063172PF02750
DomainSynapsin

SYN3 SYN1

2.34e-063172PF02078
DomainSYNAPSIN_1

SYN3 SYN1

2.34e-063172PS00415
DomainSYNAPSIN_2

SYN3 SYN1

2.34e-063172PS00416
DomainSynapsin_CS

SYN3 SYN1

2.34e-063172IPR019735
DomainSynapsin_P_site

SYN3 SYN1

2.34e-063172IPR019736
DomainSynapsin

SYN3 SYN1

2.34e-063172IPR001359
DomainSynapsin_N

SYN3 SYN1

2.34e-063172PF10581
DomainHMGI/Y_DNA-bd_CS

PRB1 PRB3 PRB2

2.77e-0631173IPR000637
Domain-

SYN3 SYN1

6.05e-05131723.40.50.20
DomainPreATP-grasp_dom

SYN3 SYN1

7.05e-0514172IPR016185
Domain-

SYN3 SYN1

8.13e-05151723.30.1490.20
Domain-

SYN3 SYN1

1.18e-04181723.30.470.20
DomainATP_grasp_subdomain_1

SYN3 SYN1

1.18e-0418172IPR013815
DomainATP_grasp_subdomain_2

SYN3 SYN1

3.57e-0431172IPR013816
DomainUbiquitin-rel_dom

HERPUD1 UBXN6

1.19e-02184172IPR029071
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

SYN3 SYN1

1.60e-0418152M27043
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

SYN3 SYN1

1.60e-0418152MM14702
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

SYN3 SYN1

2.64e-0423152MM14852
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

SYN3 SYN1

2.64e-0423152M12627
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

SYN3 SYN1

1.31e-0351152M39457
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SYN3 SYN1

1.31e-0351152MM14499
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SYN3 SYN1

1.31e-0351152M4281
Pubmed

The involvement of proline-rich protein Mus musculus predicted gene 4736 in ocular surface functions.

PRB1 PRB3 PRB2

4.65e-10418327588265
Pubmed

Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.

PRB1 PRB3 PRB2

4.65e-1041832851479
Pubmed

Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.

PRB1 PRB3 PRB2

2.33e-0961832993301
Pubmed

Fractionation and characterization of basic proline-rich peptides of human parotid saliva and the amino acid sequence of proline-rich peptide P-E.

PRB1 PRB2

2.53e-0721827118863
Pubmed

Basic proline-rich proteins from human parotid saliva: complete covalent structure of protein IB-9 and partial structure of protein IB-6, members of a polymorphic pair.

PRB1 PRB2

2.53e-0721826924859
Pubmed

Clones from the human gene complex coding for salivary proline-rich proteins.

PRB1 PRB2

2.53e-0721826089212
Pubmed

Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.

SYN3 SYN1

7.59e-07318221621590
Pubmed

Synapsins differentially control dopamine and serotonin release.

SYN3 SYN1

7.59e-07318220660258
Pubmed

Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission.

SYN3 SYN1

7.59e-07318222805168
Pubmed

Synapsin condensation controls synaptic vesicle sequestering and dynamics.

SYN3 SYN1

7.59e-07318237872159
Pubmed

DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression.

SYN3 SYN1

7.59e-07318227515700
Pubmed

The Knockout of Synapsin II in Mice Impairs Social Behavior and Functional Connectivity Generating an ASD-like Phenotype.

SYN3 SYN1

7.59e-07318228922833
Pubmed

Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.

SYN3 SYN1

7.59e-07318218945891
Pubmed

The structure and evolution of the human salivary proline-rich protein gene family.

PRB1 PRB2

7.59e-0731828422499
Pubmed

Molecular genetics of human salivary proteins and their polymorphisms.

PRB1 PRB3

7.59e-0731823055850
Pubmed

Autism-related behavioral abnormalities in synapsin knockout mice.

SYN3 SYN1

7.59e-07318223280234
Pubmed

Synapsin Isoforms Regulating GABA Release from Hippocampal Interneurons.

SYN3 SYN1

7.59e-07318227335405
Pubmed

Synapsins contribute to the dynamic spatial organization of synaptic vesicles in an activity-dependent manner.

SYN3 SYN1

7.59e-07318222933803
Pubmed

Synapsins regulate brain-derived neurotrophic factor-mediated synaptic potentiation and axon elongation by acting on membrane rafts.

SYN3 SYN1

7.59e-07318228245069
Pubmed

Temporal evolution of neurophysiological and behavioral features of synapsin I/II/III triple knock-out mice.

SYN3 SYN1

7.59e-07318222846639
Pubmed

Synapsin 2a tetramerisation selectively controls the presynaptic nanoscale organisation of reserve synaptic vesicles.

SYN3 SYN1

7.59e-07318238472171
Pubmed

Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.

SYN3 SYN1

7.59e-07318216554471
Pubmed

The Lack of Synapsin Alters Presynaptic Plasticity at Hippocampal Mossy Fibers in Male Mice.

SYN3 SYN1

7.59e-07318238866497
Pubmed

Synaptic and extrasynaptic origin of the excitation/inhibition imbalance in the hippocampus of synapsin I/II/III knockout mice.

SYN3 SYN1

7.59e-07318222368083
Pubmed

ERK activation in axonal varicosities modulates presynaptic plasticity in the CA3 region of the hippocampus through synapsin I.

SYN3 SYN1

7.59e-07318219487674
Pubmed

Maternal synapsin autoantibodies are associated with neurodevelopmental delay.

SYN3 SYN1

7.59e-07318236742338
Pubmed

Different presynaptic roles of synapsins at excitatory and inhibitory synapses.

SYN3 SYN1

7.59e-07318215601943
Pubmed

Synapsin selectively controls the mobility of resting pool vesicles at hippocampal terminals.

SYN3 SYN1

7.59e-07318222442064
Pubmed

Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin.

SYN3 SYN1

7.59e-07318218077680
Pubmed

Molecular evolution of the synapsin gene family.

SYN3 SYN1

7.59e-07318210578110
Pubmed

Epileptic synapsin triple knockout mice exhibit progressive long-term aberrant plasticity in the entorhinal cortex.

SYN3 SYN1

7.59e-07318223236212
Pubmed

Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam.

SYN3 SYN1

7.59e-07318220804820
Pubmed

The readily-releasable pool dynamically regulates multivesicular release.

SYN3 SYN1

7.59e-07318231364987
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

RBM33 WDR33 GARRE1 R3HDM1

1.02e-0615218438360978
Pubmed

cDNA clones for mouse parotid proline-rich proteins. mRNA regulation by isoprenaline and the nucleotide sequence of proline-rich protein cDNA MP5.

PRB1 PRB3

1.52e-0641821339347
Pubmed

Ubxd1 is a novel co-factor of the human p97 ATPase.

HERPUD1 UBXN6

1.52e-06418218656546
Pubmed

Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

SYN3 SYN1

2.53e-06518211867766
Pubmed

The intriguing heterogeneity of human salivary proline-rich proteins: Short title: Salivary proline-rich protein species.

PRB3 PRB2

2.53e-06518226375204
Pubmed

Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.

SEL1L HERPUD1

2.53e-06518226471130
Pubmed

Homo- and heterodimerization of synapsins.

SYN3 SYN1

2.53e-06518210358015
Pubmed

Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).

SEL1L HERPUD1

3.79e-06618228827405
Pubmed

Development of the mouse neuromuscular junction in the absence of regulated secretion.

SYN3 SYN1

7.07e-06818212895513
Pubmed

Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality.

SEL1L HERPUD1

7.07e-06818220197277
Pubmed

Molecular determinants of synapsin targeting to presynaptic terminals.

SYN3 SYN1

7.07e-06818215071120
Pubmed

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation.

SYN3 SEL1L UBXN6

7.99e-067618329599191
Pubmed

gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.

SEL1L HERPUD1

1.39e-051118226424800
Pubmed

Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum.

SEL1L HERPUD1

1.66e-051218223867461
Pubmed

NANOS2 promotes male germ cell development independent of meiosis suppression.

PRB3 PRB2

3.85e-051818224183939
Pubmed

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK).

SEL1L HERPUD1

4.30e-051918225660456
Pubmed

Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.

SYN3 SYN1

4.30e-051918215529118
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

RBM33 WDR33 R3HDM1

1.05e-0418018335198878
Pubmed

The synaptic vesicle cycle.

SYN3 SYN1

1.17e-043118215217342
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MED25 RBM33 WDR33 GARRE1

2.05e-0458818438580884
Pubmed

Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

HERPUD1 R3HDM1

2.26e-04431827584026
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RBM33 WDR33 HERPUD1 R3HDM1

4.73e-0473318434672954
InteractionALG13 interactions

RBM33 WDR33 GARRE1 R3HDM1

1.82e-05183184int:ALG13
InteractionEYA4 interactions

RBM33 WDR33 GARRE1 R3HDM1

5.52e-05243184int:EYA4
Cytoband12p13.2

PRB1 PRB3 PRB2

7.11e-074518312p13.2
CytobandEnsembl 112 genes in cytogenetic band chr12p13

PRB1 PRB3 PRB2

3.38e-04353183chr12p13
GeneFamilyProline rich proteins

PRB1 PRB3 PRB2

4.46e-096123972
GeneFamilySynapsins

SYN3 SYN1

1.21e-0631221325
CoexpressionTRAVAGLINI_LUNG_SEROUS_CELL

PRB1 PRB3 PRB2

3.73e-0596183M41657
CoexpressionAtlassalivary gland

PRB1 PRB3 PRB2

4.50e-0583183salivary gland
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 HERPUD1 PRB2

9.19e-0719118413460059a0c1ed9f476cef28b8ad4c06349056c6
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 HERPUD1 PRB2

9.58e-0719318456145861ef5e7655db9ad0d11b82f72dcadf285d
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 HERPUD1 PRB2

9.58e-071931843d1710a6060d3a70994a206334ccb16cd63e5f20
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB1 PRB3 PRB2

5.25e-051841835433ba7bbab553ff668619822d1a9208e15cd59f
ToppCellSerous|World / shred by cell class for bronchial biopsy

PRB1 PRB3 PRB2

5.25e-0518418309d0d1525c11dd326efd942684c03f79d992cf3b
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB1 PRB3 PRB2

5.25e-05184183f0cbb5b76e092be4188a9804ef5cf7a83cd7644f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-SMG_serous_secreting_cell-SMG_serous_(nasal)-SMG_serous_(nasal)_L.0.6.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

5.59e-0518818302b3aae071ff1f469d52a4d513a4eb46ae70bba3
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-SMG_serous_secreting_cell-SMG_serous_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

5.77e-05190183e3a07dcffb75375693738bef1668353f4cdba5d7
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-SMG_serous_secreting_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

5.77e-05190183f6f8451eef5a387b0a1fd2e90ab965928ea2ea82
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

5.96e-0519218348b69d6f46e583378186d2993a202f9584688bfa
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB1 PRB3 PRB2

6.14e-05194183d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRB1 PRB3 PRB2

6.14e-05194183e90f6717e3421f8978d1fc1b2f30dcf69f6fcce7
ToppCell3'-Broncho-tracheal_SMG-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

6.14e-05194183f1d057c4bf57e75ad5a821e5f3de335dbff69062
ToppCell3'-Broncho-tracheal_SMG|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

6.14e-0519418342558822d7e260e7d8cf2539f1f7426e5774edfb
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRB1 PRB3 PRB2

6.14e-051941830d97dee07846416c77a861994912a9207f29ceb3
ToppCellproximal-Epithelial-Serous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRB1 PRB3 PRB2

6.24e-0519518306b73abc1f32543f2a51db52dc6424a2a398fe0f
ToppCellproximal-Epithelial-Serous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRB1 PRB3 PRB2

6.24e-05195183cb62f04f0e45bfb36eed2e7a3fc54d6d390b2ed1
ToppCellproximal-3-Epithelial-Serous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRB1 PRB3 PRB2

6.24e-0519518324a6a566143b04e37ad002e4c55037a0460ac2ef
ToppCellcellseq2|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB1 PRB3 PRB2

6.33e-05196183d9e1b8386817a668eca90288b6d0e20be4138bf8
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRB1 PRB3 PRB2

6.43e-0519718392a66e3b5ddc3d55527c31e0d9cff15c2203ecfc
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB1 PRB3 PRB2

6.43e-05197183d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRB1 PRB3 PRB2

6.43e-05197183e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRB1 PRB3 PRB2

6.43e-0519718340bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRB1 PRB3 PRB2

6.52e-05198183162881a04a981741a0e26e32e0c3c694282701c6
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRB1 PRB3 PRB2

6.72e-0520018361bae10c8b12196d9cee766897971b81cb897191
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRB1 PRB3 PRB2

6.72e-05200183e9908b6cba21a59023cf8d0f98fbd1d1f7de6b44
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-7|TCGA-Breast / Sample_Type by Project: Shred V9

PRB1 PRB2

9.16e-041121820a2cb8b1339a397e11fcf9e48258bdfa2e89a3ce
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6|TCGA-Bladder / Sample_Type by Project: Shred V9

PRB1 PRB2

9.98e-04117182e13c50260d81e8f2ea99e5c680c9699da246067b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-7|TCGA-Pancreas / Sample_Type by Project: Shred V9

PRB1 PRB2

1.12e-03124182c6e0c45e9ac128540baddfeb4599a0d5ec3f14cb
ToppCellCOVID-19_Severe-MAIT|World / disease group, cell group and cell class

ADAMTSL5 GARRE1

1.53e-031451828d63f97812f63329ef9c940b291dc5a1c4d90690
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SHISAL1 MAGEL2

1.59e-031481824d43efee96a6493abd78e9ca41aab73db0c80626
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

SYN3 ADAMTSL5

1.59e-0314818281a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellCOVID-19_Severe-MAIT|COVID-19_Severe / disease group, cell group and cell class

ADAMTSL5 GARRE1

1.63e-03150182923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

1.70e-031531823724dd498b982be693ddff9cea7671863acf3ff8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

1.70e-03153182d810fc5aff28449ce79b4148558b260878a2c696
ToppCellGoblet|World / Class top

PRB1 HERPUD1

1.78e-03157182b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEL1L HERPUD1

1.78e-0315718263502d0fd5972d71cdbe13bde167592c70acec32
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL5 SHISAL1

1.81e-03158182d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

1.81e-031581826b51e5ee08e23924f5edbaf0a845a9232fb7ff7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL5 SHISAL1

1.81e-03158182e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

1.81e-031581828dd83a2a4c2ec9cdc3a03df8b51ee22bee1c2888
ToppCellGoblet-gob-1|World / Class top

PRB1 HERPUD1

1.83e-0315918262d4ca2b538382419252e306d7a789b64420fb18
ToppCellCOVID-19-kidney-Plasma|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEL1L HERPUD1

1.85e-03160182f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYN1 SHISAL1

1.90e-03162182f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYN1 SHISAL1

1.90e-03162182c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYN1 SHISAL1

1.90e-031621825d902bb31e691aea9749617cc88303c2448f24b8
ToppCellDendritic_Cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SYN1 HERPUD1

1.92e-031631825fff3932c1c259010e3add7a3b2301df2fa37df1
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYN1 HERPUD1

1.92e-031631823087224d3f16f5d3aecc3e1e4366220231afe31f
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L HERPUD1

1.97e-0316518221a82a975f550080b6674750b06212205cd16742
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEL1L HERPUD1

1.97e-031651829e2fa634f4749e35aa5dca43476477b5d362afd7
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYN1 MAGEL2

1.97e-031651824e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEL1L HERPUD1

1.97e-0316518279c6ad394266ff092029375883660028e944a3c8
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL5 YBX2

1.99e-031661827495961adcefe5c1fb288913b1a5236328a04703
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

GARRE1 R3HDM1

1.99e-031661829afa33b5ad27dc33576be592f9b22d8161366838
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL5 SYN1

2.02e-03167182fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

2.02e-031671820130743084dbcb20e10f96715d30961122150cbf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

2.02e-03167182c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEL1L HERPUD1

2.02e-031671827bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYN1 SHISAL1

2.02e-03167182d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GARRE1 YBX2

2.04e-0316818232e4d82efaccf336d347e4063253c3635a3ec672
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEL1L HERPUD1

2.06e-031691820c2384f780ec25710ebb35c0b0df8f4afb53c9b1
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

SEL1L HERPUD1

2.09e-0317018253634da9e9c72f6400639954c286c6e38ea5a188
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

SEL1L HERPUD1

2.11e-03171182a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PRB1 PRB3

2.14e-031721826b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEL1L HERPUD1

2.16e-031731820ca2169a275404118038c0489a48062879488765
ToppCell5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYN1 HERPUD1

2.16e-03173182b335ca2a247156eba821943b2b9fc9922230b409
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

SEL1L HERPUD1

2.16e-03173182300904fd35536a69be81d76fe33fe16544523ceb
ToppCellPlasma_cells|World / lung cells shred on cell class, cell subclass, sample id

SEL1L HERPUD1

2.16e-0317318252a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEL1L HERPUD1

2.16e-0317318268bcc0eee15df9cf3516c641709154301bd7b38f
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHISAL1 GARRE1

2.16e-03173182b57d14e2c2368304cb903562d06ce8228f53857c
ToppCellfacs-Marrow-KLS-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYN3 SEL1L

2.16e-03173182295bfe1efa648173c2d5981025bc61c576baf53f
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma|bone_marrow / Manually curated celltypes from each tissue

SEL1L HERPUD1

2.18e-03174182b1931028cf80af5eff6da15d7f0196205f17926f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HERPUD1 YBX2

2.18e-03174182c2fc78dd6c440737ded59676961e4c7b923084ce
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HERPUD1 YBX2

2.18e-03174182021ebc6ec022b992d7b25333ba0b7416371e041b
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L HERPUD1

2.18e-031741823b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRB1 PRB2

2.21e-031751828727252bcbc70bfa2ff72e7421df9cfe6fd4eed7
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEL1L HERPUD1

2.21e-03175182ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

SEL1L HERPUD1

2.21e-03175182fb23858cfce71509cafbe0d9728e678012ff2962
ToppCellfacs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L HERPUD1

2.21e-031751824be01bf30331162f1998216fb2871a4e626dc440
ToppCellfacs-Marrow-T-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L HERPUD1

2.21e-031751820a01e0104cfa3091bc05b0f1d087c941688169a5
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRB1 PRB2

2.21e-03175182c083abe368e5c0dc2b0f27f375c9271a2d7ff64f
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEL1L HERPUD1

2.21e-0317518228b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCell(03)_Secretory-(4)_1wkpi|(03)_Secretory / shred by cell type and Timepoint

SEL1L HERPUD1

2.21e-0317518206b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEL1L HERPUD1

2.23e-03176182125be81311f87563ca321472fcce6e0e0ae24c16
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 R3HDM1

2.23e-03176182212e643c50c68462d4b016428ab30eeb7868ef40
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 R3HDM1

2.23e-0317618207abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

SEL1L HERPUD1

2.23e-031761829125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L HERPUD1

2.23e-03176182acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 R3HDM1

2.23e-03176182c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L HERPUD1

2.23e-03176182606704098bfdf8bfef740a3544a372fae1e75969
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEL1L HERPUD1

2.23e-0317618267d6dc38708692f8c58cea5ed896f10718e9ffa6
ToppCell-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SEL1L HERPUD1

2.26e-03177182ae2d2e138946535596fa30a55207f261cafda461
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MED25 SYN1

2.26e-03177182164ffbbf798defa3728197deb1a14b661490e525
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 R3HDM1

2.26e-031771828b003ed7887479c3a010ef37dd981b748256bda7
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYN3 SHISAL1

2.26e-0317718212f8627124acbf436e75681ff1ce429ff5e3f256
ToppCellNS-critical-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SEL1L HERPUD1

2.26e-03177182bbea488582f1eb863950c660afed9159630f6960
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYN3 SHISAL1

2.26e-03177182fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L R3HDM1

2.26e-03177182c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCelltumor_Lung-B_lymphocytes-MALT_B_cells|tumor_Lung / Location, Cell class and cell subclass

SEL1L HERPUD1

2.26e-0317718237e03f51925345f5f716ef3abe1d2c4ccf129020
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEL1L R3HDM1

2.26e-03177182ff97398d2adb83063b7c53a264bfae86ea7ea304
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

SEL1L WDR33 HERPUD1 R3HDM1

1.06e-051801845223_UP
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A

SEL1L MED25 SHISAL1 HERPUD1

1.31e-051901845786_UP
DrugAlthiazide [5588-16-9]; Down 200; 10.4uM; PC3; HT_HG-U133A

MED25 SHISAL1 WDR33 R3HDM1

1.48e-051961844491_DN
DrugCloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; PC3; HT_HG-U133A

SEL1L MED25 SS18 SHISAL1

1.51e-051971842126_DN
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

SYN3 SEL1L SS18 YBX2

1.54e-051981843743_UP
DrugButirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A

MED25 SHISAL1 WDR33 R3HDM1

1.57e-051991846080_UP
DrugPS-5

PRB1 HERPUD1

2.65e-0510182CID000196445
DrugC06784

PRB1 HERPUD1

6.16e-0515182CID000441178
Drug2brh

SYN3 SYN1

1.23e-0421182CID000848641
DrugAC1NRB38

SYN3 SYN1

2.20e-0428182CID005288237
DrugAC1L1AUZ

SYN3 SYN1 HERPUD1

2.43e-04157183CID000001160
DrugSpiperone [749-02-0]; Up 200; 10.2uM; PC3; HT_HG-U133A

SEL1L MED25 HERPUD1

2.67e-041621835777_UP
DrugAC1MO08Q

SYN3 SYN1

2.71e-0431182CID003336188
Drugthapsigargin; Up 200; 0.1uM; MCF7; HT_HG-U133A

SEL1L WDR33 HERPUD1

3.07e-041701837053_UP
DrugCyclosporin A [59865-13-3]; Up 200; 3.4uM; PC3; HT_HG-U133A

SEL1L SHISAL1 HERPUD1

3.18e-041721834586_UP
DrugPhenoxybenzamine hydrochloride [63-92-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

SEL1L HERPUD1 GARRE1

3.23e-041731836451_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

SEL1L WDR33 HERPUD1

3.29e-041741835215_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

SEL1L WDR33 HERPUD1

3.35e-041751831006_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

SEL1L WDR33 HERPUD1

3.35e-041751835222_UP
Drugpantoprazole

PRB1 HERPUD1

3.46e-0435182CID000004679
DrugChlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; PC3; HT_HG-U133A

SEL1L SS18 HERPUD1

3.46e-041771831822_UP
Druggeldanamycin; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L MED25 HERPUD1

3.57e-041791834452_UP
DrugTriamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A

SEL1L SS18 HERPUD1

3.57e-041791831819_UP
DrugAzacyclonol [115-46-8]; Up 200; 15uM; PC3; HG-U133A

SEL1L SHISAL1 HERPUD1

3.63e-041801831937_UP
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L WDR33 HERPUD1

3.81e-041831831206_UP
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L WDR33 HERPUD1

3.94e-041851831226_UP
Druggeldanamycin; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L WDR33 HERPUD1

4.00e-041861831228_UP
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L WDR33 HERPUD1

4.06e-041871831218_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

SEL1L WDR33 HERPUD1

4.13e-041881836926_UP
DrugForskolin, from Coleus forskohlii; Up 200; 0.5uM; PC3; HT_HG-U133A

SEL1L SS18 SHISAL1

4.13e-041881837104_UP
DrugGSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A

MED25 SS18 GARRE1

4.13e-041881837097_DN
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L WDR33 HERPUD1

4.19e-041891831225_UP
DrugLidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A

SEL1L WDR33 R3HDM1

4.26e-041901834421_DN
DrugDomperidone maleate; Up 200; 7.4uM; HL60; HT_HG-U133A

SEL1L SS18 HERPUD1

4.46e-041931831301_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

SEL1L MED25 HERPUD1

4.46e-041931835914_UP
DrugCotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HT_HG-U133A

MED25 SS18 SHISAL1

4.46e-041931834650_DN
DrugDiprophylline [479-18-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

SEL1L SHISAL1 UBXN6

4.46e-041931831811_DN
DrugClemizole hydrochloride [1163-36-6]; Down 200; 11uM; PC3; HT_HG-U133A

MED25 SS18 WDR33

4.46e-041931833672_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A

SEL1L WDR33 R3HDM1

4.46e-041931834410_DN
DrugLynestrenol [52-76-6]; Down 200; 14uM; PC3; HT_HG-U133A

MED25 SS18 WDR33

4.52e-041941836756_DN
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A

SEL1L SS18 HERPUD1

4.52e-041941832068_UP
DrugProstaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A

MED25 SS18 GARRE1

4.52e-041941836555_DN
DrugFluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

MED25 GARRE1 UBXN6

4.52e-041941833194_DN
DrugH-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A

SEL1L SHISAL1 YBX2

4.59e-041951836873_UP
DrugST021200; Down 200; 10uM; PC3; HT_HG-U133A

SHISAL1 WDR33 GARRE1

4.59e-041951837493_DN
DrugTrimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A

SEL1L SS18 SHISAL1

4.59e-041951837377_UP
DrugKawain [500-64-1]; Up 200; 17.4uM; PC3; HT_HG-U133A

SEL1L SHISAL1 R3HDM1

4.66e-041961837369_UP
DrugGemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A

SEL1L SS18 SHISAL1

4.66e-041961832113_DN
DrugAdamantamine fumarate [80789-67-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A

SEL1L SS18 R3HDM1

4.66e-041961834806_UP
DrugPralidoxime chloride [51-15-0]; Down 200; 23.2uM; HL60; HT_HG-U133A

SS18 WDR33 UBXN6

4.66e-041961833066_DN
DrugTroleandomycin [2751-09-9]; Down 200; 5uM; PC3; HT_HG-U133A

MED25 SS18 WDR33

4.66e-041961833985_DN
DrugTodralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A

SEL1L SS18 UBXN6

4.66e-041961831841_DN
DrugNicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A

SEL1L SS18 SHISAL1

4.66e-041961832058_UP
DrugSulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; MCF7; HT_HG-U133A

SEL1L MED25 R3HDM1

4.73e-041971836090_UP
DrugBezafibrate [41859-67-0]; Up 200; 11uM; HL60; HT_HG-U133A

SEL1L SS18 WDR33

4.73e-041971831275_UP
DrugTrifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; PC3; HT_HG-U133A

SEL1L SS18 HERPUD1

4.73e-041971836341_UP
DrugHydroflumethiazide [135-09-1]; Down 200; 12uM; PC3; HT_HG-U133A

MED25 SS18 SHISAL1

4.73e-041971831809_DN
DrugSulfameter [651-06-9]; Up 200; 14.2uM; PC3; HT_HG-U133A

SYN3 SEL1L MED25

4.73e-041971835732_UP
DrugFlupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; PC3; HT_HG-U133A

MED25 SHISAL1 HERPUD1

4.73e-041971836708_UP
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; PC3; HT_HG-U133A

SEL1L MED25 SHISAL1

4.73e-041971831796_DN
DrugGliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A

SS18 WDR33 GARRE1

4.73e-041971832870_DN
Drug0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A

SEL1L HERPUD1 R3HDM1

4.80e-041981837391_UP
DrugLaudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; PC3; HT_HG-U133A

SEL1L MED25 R3HDM1

4.80e-041981837270_UP
DrugPentolinium bitartrate [52-62-0]; Down 200; 7.4uM; PC3; HT_HG-U133A

MED25 SHISAL1 GARRE1

4.80e-041981833676_DN
DrugGlipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A

SEL1L SS18 UBXN6

4.80e-041981834991_DN
DrugPiretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A

SS18 GARRE1 UBXN6

4.80e-041981836144_DN
DrugCinoxacin [28657-80-9]; Up 200; 15.2uM; PC3; HT_HG-U133A

SYN3 MED25 SHISAL1

4.87e-041991835783_UP
DrugDiethylstilbestrol [56-53-1]; Up 200; 15uM; HL60; HT_HG-U133A

SEL1L MED25 SS18

4.87e-041991832567_UP
Drugclozapine; Up 200; 10uM; HL60; HT_HG-U133A

SEL1L MED25 SS18

4.87e-041991836188_UP
DrugTelenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; HL60; HT_HG-U133A

MED25 SS18 GARRE1

4.87e-041991832388_UP
DrugDehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; HL60; HT_HG-U133A

SYN3 SEL1L MED25

4.87e-041991833097_UP
DrugNalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A

SS18 SHISAL1 WDR33

4.87e-041991833668_DN
DrugBumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A

SEL1L MED25 WDR33

4.87e-041991835542_UP
DrugRacecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

SEL1L SHISAL1 YBX2

4.94e-042001835755_UP
DrugNaproxen [22204-53-1]; Up 200; 17.4uM; HL60; HT_HG-U133A

MED25 SS18 GARRE1

4.94e-042001831869_UP
Drugchlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A

MED25 SS18 R3HDM1

4.94e-042001832677_DN
DrugPromazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A

WDR33 HERPUD1 YBX2

4.94e-042001833752_UP
Drug2-nitro-5-thiocyanobenzoic acid

SYN3 SYN1

6.52e-0448182CID000092266
Drugpolysialoganglioside

SYN3 SYN1

7.07e-0450182CID006450319
Diseaseatrophic macular degeneration, age-related macular degeneration, wet macular degeneration

SYN3 HERPUD1

5.42e-0460172EFO_0001365, EFO_0004683, EFO_1001492
Diseaseleft ventricular structural measurement

SYN3 SS18

1.16e-0388172EFO_0008205
Diseaseage-related macular degeneration

SYN3 HERPUD1

1.19e-0389172EFO_0001365
Diseaseautism spectrum disorder (implicated_via_orthology)

SYN3 SYN1

3.41e-03152172DOID:0060041 (implicated_via_orthology)
Diseaseobsolete_red blood cell distribution width

SYN3 SS18 GARRE1 R3HDM1

6.38e-031347174EFO_0005192
Diseaseperiodontitis

SS18 PRB2

7.18e-03223172EFO_0000649

Protein segments in the cluster

PeptideGeneStartEntry
QQPVRSQVPGPPQPP

R3HDM1

511

Q15032
QPQRLPQPPEVGPQP

RBM33

1006

Q96EV2
RPRPVQNFPNDGPPP

HERPUD1

311

Q15011
RAPPQVPQGPQAPPA

MAGEL2

346

Q9UJ55
PGPILRPQNPGANPQ

MED25

631

Q71SY5
QPQPRGVEPQPPAAP

ADAMTSL5

331

Q6ZMM2
IGPQQPPPQPRAPGK

GARRE1

741

O15063
PQAPPAGQPQGPPRP

PRB2

391

P02812
QPAGPPAQQRPPPQG

SYN1

451

P17600
PAQQRPPPQGGPPQP

SYN1

456

P17600
GPGPQRQGPPLQQRP

SYN1

471

P17600
RQGPPLQQRPPPQGQ

SYN1

476

P17600
PPGGQQRQGPPQKPP

SYN1

581

P17600
GPQLGQPQPRPPPQG

SYN3

426

O14994
QPQPRPPPQGGPRQA

SYN3

431

O14994
PPPQGGPRQAQSPQP

SYN3

436

O14994
GPRPAPPQQEGPPEQ

SEL1L

776

Q9UBV2
PRPGQRAPQPQPPPG

SHISAL1

156

Q3SXP7
PQGPPPQEGNKPQRP

PRB3

246

Q04118
PQEGNKPQRPPPPGR

PRB3

251

Q04118
QPQAPPAGQPQGPPR

PRB1

366

P04280
QAPGPQQAPGPRQPA

YBX2

331

Q9Y2T7
PNQPAPRPPRQGPTN

UBXN6

36

Q9BZV1
GQRQIPPYRPPQQGP

SS18

246

Q15532
RPTQPGPPQPPQQRP

SS18

391

Q15532
QGPQGPPQGLPRPQD

WDR33

656

Q9C0J8