Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2A SUV39H2

4.89e-0444152GO:0140938
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2A SUV39H2

1.17e-0368152GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2A SUV39H2

1.20e-0369152GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2A SUV39H2

1.27e-0371152GO:0042054
GeneOntologyMolecularFunctionprotein methyltransferase activity

KMT2A SUV39H2

2.65e-03103152GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

KMT2A SUV39H2

2.75e-03105152GO:0008170
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

KMT2A SUV39H2

7.20e-03172152GO:0008757
GeneOntologyMolecularFunctionmethyltransferase activity

KMT2A SUV39H2

1.09e-02213152GO:0008168
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

KMT2A SUV39H2

1.19e-02224152GO:0016741
GeneOntologyMolecularFunctionhistone modifying activity

KMT2A SUV39H2

1.25e-02229152GO:0140993
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

CRIM1 SKIL VWC2L KCP

2.01e-06131154GO:0030510
GeneOntologyBiologicalProcessBMP signaling pathway

CRIM1 SKIL VWC2L KCP

1.01e-05197154GO:0030509
GeneOntologyBiologicalProcessresponse to BMP

CRIM1 SKIL VWC2L KCP

1.43e-05215154GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

CRIM1 SKIL VWC2L KCP

1.43e-05215154GO:0071773
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

CRIM1 SKIL VWC2L

2.47e-0580153GO:0030514
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CRIM1 SKIL VWC2L KCP

9.28e-05347154GO:0090092
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

CRIM1 SKIL VWC2L

1.61e-04150153GO:0090288
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

CRIM1 SKIL VWC2L KCP

1.80e-04412154GO:0090287
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

CRIM1 SKIL VWC2L KCP

2.42e-04445154GO:0141091
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

CRIM1 SKIL VWC2L KCP KMT2A

2.50e-04850155GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

CRIM1 SKIL VWC2L KCP KMT2A

2.98e-04883155GO:0070848
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

CRIM1 SKIL VWC2L KCP

3.28e-04482154GO:0007178
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CRIM1 SKIL VWC2L

4.82e-04218153GO:0090101
GeneOntologyBiologicalProcesscircadian rhythm

KMT2A SUV39H2 AGRP

7.02e-04248153GO:0007623
GeneOntologyBiologicalProcessregulation of neuron differentiation

VWC2L JAG1 NOTCH3

7.61e-04255153GO:0045664
GeneOntologyBiologicalProcessglomerulus development

JAG1 NOTCH3

1.40e-0377152GO:0032835
GeneOntologyBiologicalProcessartery morphogenesis

JAG1 NOTCH3

1.99e-0392152GO:0048844
GeneOntologyBiologicalProcessrhythmic process

KMT2A SUV39H2 AGRP

2.05e-03360153GO:0048511
GeneOntologyBiologicalProcessnegative regulation of neuron differentiation

JAG1 NOTCH3

2.08e-0394152GO:0045665
MousePhenoincreased B cell derived lymphoma incidence

SKIL KMT2A SUV39H2

2.39e-0558143MP:0002023
DomainVWC

CRIM1 VWCE VWC2L KCP MUC5B JAG1 FCGBP

5.11e-1638157SM00214
DomainVWF_dom

CRIM1 VWCE VWC2L KCP MUC5B JAG1 FCGBP

1.09e-1542157IPR001007
DomainVWC_out

CRIM1 VWCE KCP MUC5B JAG1 FCGBP

2.29e-1519156SM00215
DomainVWFC_1

CRIM1 VWCE VWC2L KCP MUC5B

5.90e-1136155PS01208
DomainVWFC_2

CRIM1 VWCE VWC2L KCP MUC5B

7.85e-1138155PS50184
DomainVWC

CRIM1 VWCE KCP MUC5B

5.45e-0928154PF00093
DomainC8

KCP MUC5B FCGBP

1.19e-0713153SM00832
DomainUnchr_dom_Cys-rich

KCP MUC5B FCGBP

1.19e-0713153IPR014853
DomainTIL_dom

KCP MUC5B FCGBP

1.52e-0714153IPR002919
DomainVWFD

KCP MUC5B FCGBP

2.33e-0716153PS51233
DomainVWD

KCP MUC5B FCGBP

2.33e-0716153SM00216
DomainVWF_type-D

KCP MUC5B FCGBP

2.33e-0716153IPR001846
DomainVWD

KCP MUC5B FCGBP

2.33e-0716153PF00094
DomainGrowth_fac_rcpt_

CRIM1 VWCE JAG1 NOTCH3

5.95e-06156154IPR009030
DomainEGF_extracell

ITGB7 JAG1 NOTCH3

1.40e-0560153IPR013111
DomainEGF_2

ITGB7 JAG1 NOTCH3

1.40e-0560153PF07974
DomainEGF

VWCE JAG1 NOTCH3 FCGBP

2.99e-05235154SM00181
DomainEGF-like_dom

VWCE JAG1 NOTCH3 FCGBP

3.75e-05249154IPR000742
DomainTIL

MUC5B FCGBP

3.96e-0512152PF01826
DomainC8

MUC5B FCGBP

3.96e-0512152PF08742
DomainEGF_1

VWCE ITGB7 JAG1 NOTCH3

4.12e-05255154PS00022
DomainEGF_CA

VWCE JAG1 NOTCH3

4.12e-0586153PF07645
DomainEGF-like_CS

VWCE ITGB7 JAG1 NOTCH3

4.51e-05261154IPR013032
DomainEGF_2

VWCE ITGB7 JAG1 NOTCH3

4.78e-05265154PS01186
DomainEGF_Ca-bd_CS

VWCE JAG1 NOTCH3

5.91e-0597153IPR018097
DomainEGF_CA

VWCE JAG1 NOTCH3

6.28e-0599153PS01187
DomainASX_HYDROXYL

VWCE JAG1 NOTCH3

6.47e-05100153PS00010
DomainPostSET

KMT2A SUV39H2

7.18e-0516152SM00508
DomainPost-SET_dom

KMT2A SUV39H2

7.18e-0516152IPR003616
DomainPOST_SET

KMT2A SUV39H2

7.18e-0516152PS50868
DomainEGF-type_Asp/Asn_hydroxyl_site

VWCE JAG1 NOTCH3

7.69e-05106153IPR000152
DomainEGF_CA

VWCE JAG1 NOTCH3

1.17e-04122153SM00179
DomainEGF-like_Ca-bd_dom

VWCE JAG1 NOTCH3

1.23e-04124153IPR001881
DomainhEGF

JAG1 NOTCH3

2.25e-0428152PF12661
DomainSET

KMT2A SUV39H2

4.85e-0441152PF00856
DomainSET

KMT2A SUV39H2

6.11e-0446152SM00317
DomainSET_dom

KMT2A SUV39H2

7.21e-0450152IPR001214
DomainSET

KMT2A SUV39H2

7.21e-0450152PS50280
DomainEGF_3

VWCE JAG1 NOTCH3

8.00e-04235153PS50026
DomainEGF

JAG1 NOTCH3

4.48e-03126152PF00008
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

JAG1 NOTCH3

2.38e-051292M47532
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG1 NOTCH3

2.82e-051392M47423
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG1 NOTCH3

6.16e-051992MM15594
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG1 NOTCH3

1.08e-042592M27879
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG1 NOTCH3

1.26e-042792M39545
PathwayWP_CIRCADIAN_RHYTHM_GENES

KMT2A SUV39H2 AGRP

2.25e-0420193M39605
PathwayWP_NEOVASCULARIZATION_PROCESSES

JAG1 NOTCH3

2.39e-043792M39506
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG1 NOTCH3

2.65e-043992MM14604
PathwayWP_NOTCH_SIGNALING_WP268

JAG1 NOTCH3

3.54e-044592M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG1 NOTCH3

3.70e-044692MM15971
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2A SUV39H2

3.70e-044692MM14933
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG1 NOTCH3

3.86e-044792M7946
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG1 NOTCH3

4.20e-044992M618
PathwayPID_NOTCH_PATHWAY

JAG1 NOTCH3

6.08e-045992M17
PathwayWP_NOTCH_SIGNALING_WP61

JAG1 NOTCH3

6.50e-046192M39540
PathwayWP_LUNG_FIBROSIS

SKIL MUC5B

6.93e-046392M39477
PathwayWP_HISTONE_MODIFICATIONS

KMT2A SUV39H2

7.38e-046592M39374
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC5B NOTCH3

8.08e-046892M27303
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

SKIL KMT2A AGRP JAG1 NOTCH3

8.22e-04138795M734
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2A SUV39H2

8.56e-047092M27231
PathwayWP_LUNG_FIBROSIS

SKIL MUC5B

9.30e-047392MM15827
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG1 NOTCH3

1.17e-038292MM15922
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG1 NOTCH3

2.41e-0311892M39852
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC5B NOTCH3

3.51e-0314392M27275
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

JAG1 NOTCH3

4.43e-0316192M39770
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2A SUV39H2

5.21e-0317592MM14941
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG1 NOTCH3

1.01e-0224692M10189
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC5B NOTCH3

1.04e-0225092M27554
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

SKIL KMT2A NOTCH3

1.06e-0276893MM14851
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2A SUV39H2

1.22e-0227292M29619
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

SKIL KMT2A NOTCH3

2.29e-02102293MM15436
Pubmed

Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling Pathway.

JAG1 NOTCH3

1.74e-07215214714274
Pubmed

Protein and mRNA expression of notch pathway components in operable tumors of patients with laryngeal cancer.

JAG1 NOTCH3

1.74e-07215225368251
Pubmed

Mechanosensitivity of Jagged-Notch signaling can induce a switch-type behavior in vascular homeostasis.

JAG1 NOTCH3

1.74e-07215229610298
Pubmed

Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion.

JAG1 NOTCH3

1.74e-07215218632624
Pubmed

Expression of Notch 3 and Jagged 1 Is Associated With Merkel Cell Polyomavirus Status and Prognosis in Merkel Cell Carcinoma.

JAG1 NOTCH3

1.74e-07215230591475
Pubmed

Jagged1/Notch3 Signaling Modulates Hemangioma-Derived Pericyte Proliferation and Maturation.

JAG1 NOTCH3

1.74e-07215227941324
Pubmed

Expression of Jagged1/Notch3 Signaling Pathway and their Relationship with the Tumor Angiogenesis in TNBC.

JAG1 NOTCH3

1.74e-07215228625320
Pubmed

The role of endothelial cell-bound Jagged1 in Notch3-induced human coronary artery smooth muscle cell differentiation.

JAG1 NOTCH3

1.74e-07215222204979
Pubmed

NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1.

JAG1 NOTCH3

1.74e-07215219150886
Pubmed

Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL.

JAG1 NOTCH3

1.74e-07215225499214
Pubmed

Regulation of vascular smooth muscle cell phenotype in three-dimensional coculture system by Jagged1-selective Notch3 signaling.

JAG1 NOTCH3

1.74e-07215224138322
Pubmed

Prognostic Subcellular Notch2, Notch3 and Jagged1 Localization Patterns in Early Triple-negative Breast Cancer.

JAG1 NOTCH3

1.74e-07215228476798
Pubmed

Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.

JAG1 NOTCH3

5.21e-07315230502484
Pubmed

Targeted genome modification in mice using zinc-finger nucleases.

JAG1 NOTCH3

5.21e-07315220628038
Pubmed

Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development.

JAG1 NOTCH3

5.21e-0731528923452
Pubmed

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

JAG1 NOTCH3

5.21e-07315212482954
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5B JAG1 NOTCH3

6.85e-074115322675208
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

JAG1 NOTCH3

1.04e-06415219147503
Pubmed

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland.

JAG1 NOTCH3

1.04e-06415218060036
Pubmed

Association analysis of Notch pathway signalling genes in diabetic nephropathy.

JAG1 NOTCH3

1.04e-06415221103979
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

JAG1 NOTCH3

1.04e-06415210551863
Pubmed

Soluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signaling.

JAG1 NOTCH3

1.04e-06415228045060
Pubmed

Activation of Notch signaling in human tongue carcinoma.

JAG1 NOTCH3

1.04e-06415220819128
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

JAG1 NOTCH3

1.04e-06415220040020
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

JAG1 NOTCH3

1.73e-06515211006133
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

JAG1 NOTCH3

1.73e-06515215882997
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG1 NOTCH3

1.73e-06515215064243
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

JAG1 NOTCH3

1.73e-06515221602525
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

JAG1 NOTCH3

1.73e-06515220554499
Pubmed

A study on Notch signaling in human breast cancer.

JAG1 NOTCH3

2.60e-06615217822320
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

JAG1 NOTCH3

2.60e-06615219603167
Pubmed

The complex interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells.

JAG1 NOTCH3

2.60e-06615224788939
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

JAG1 NOTCH3

2.60e-06615212244553
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

JAG1 NOTCH3

2.60e-06615222526456
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

JAG1 NOTCH3

2.60e-0661529108364
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

JAG1 NOTCH3

3.64e-06715224711412
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG1 NOTCH3

3.64e-06715210383933
Pubmed

Human ligands of the Notch receptor.

JAG1 NOTCH3

3.64e-06715210079256
Pubmed

Impaired expression of Notch signaling genes in aged human skeletal muscle.

JAG1 NOTCH3

3.64e-06715217301032
Pubmed

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium.

JAG1 NOTCH3

3.64e-06715211344305
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG1 NOTCH3

3.64e-06715212846471
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG1 NOTCH3

4.85e-06815222652674
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

JAG1 NOTCH3

4.85e-06815212242716
Pubmed

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

JAG1 NOTCH3

4.85e-06815215465493
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG1 NOTCH3

4.85e-0681529858718
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

JAG1 NOTCH3

4.85e-06815222156581
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG1 NOTCH3

4.85e-06815211044610
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG1 NOTCH3

6.24e-06915211118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG1 NOTCH3

6.24e-06915216245338
Pubmed

The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression.

JAG1 NOTCH3

6.24e-06915217709399
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG1 NOTCH3

7.80e-061015223665443
Pubmed

Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.

JAG1 NOTCH3

7.80e-061015221068062
Pubmed

Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

JAG1 NOTCH3

7.80e-061015224015274
Pubmed

A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice.

JAG1 NOTCH3

7.80e-061015231590629
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG1 NOTCH3

9.53e-061115210878608
Pubmed

Pericytes are progenitors for coronary artery smooth muscle.

JAG1 NOTCH3

9.53e-061115226479710
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

JAG1 NOTCH3

9.53e-061115215499562
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

JAG1 NOTCH3

9.53e-06111529187150
Pubmed

Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor.

JAG1 NOTCH3

9.53e-061115226577899
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG1 NOTCH3

9.53e-061115212866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG1 NOTCH3

1.14e-051215215465494
Pubmed

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.

JAG1 NOTCH3

1.14e-051215232147304
Pubmed

Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.

JAG1 NOTCH3

1.14e-051215214732396
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG1 NOTCH3

1.35e-051315231202705
Pubmed

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency.

JAG1 NOTCH3

1.35e-051315234990407
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG1 NOTCH3

1.35e-051315211578869
Pubmed

Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.

JAG1 NOTCH3

1.35e-051315221632926
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

JAG1 NOTCH3

1.35e-051315220558824
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

JAG1 NOTCH3

1.58e-051415228192800
Pubmed

Defining brain wiring patterns and mechanisms through gene trapping in mice.

CRIM1 NOTCH3

1.58e-051415211242070
Pubmed

Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.

JAG1 NOTCH3

1.58e-051415225100656
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG1 NOTCH3

1.58e-051415214757642
Pubmed

Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors.

JAG1 NOTCH3

1.58e-051415225564622
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG1 NOTCH3

1.82e-051515212971992
Pubmed

Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.

KMT2A SUV39H2

1.82e-051515235907431
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG1 NOTCH3

1.82e-051515212167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG1 NOTCH3

1.82e-051515216914494
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

JAG1 NOTCH3

2.08e-051615227641601
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG1 NOTCH3

2.08e-051615212617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG1 NOTCH3

2.08e-051615210842072
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG1 NOTCH3

2.08e-051615232161758
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG1 NOTCH3

2.08e-051615217273555
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG1 NOTCH3

2.35e-051715218694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG1 NOTCH3

2.35e-051715215821257
Pubmed

Notch signalling controls pancreatic cell differentiation.

JAG1 NOTCH3

2.35e-051715210476967
Pubmed

Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens.

JAG1 NOTCH3

2.35e-051715230059908
Pubmed

Lunatic fringe null female mice are infertile due to defects in meiotic maturation.

JAG1 NOTCH3

2.65e-051815215659488
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG1 NOTCH3

2.65e-051815218093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG1 NOTCH3

2.65e-051815215689374
Pubmed

A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development.

JAG1 NOTCH3

2.96e-051915228438836
Pubmed

RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.

JAG1 NOTCH3

2.96e-051915220335360
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG1 NOTCH3

2.96e-051915216518823
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG1 NOTCH3

3.63e-052115228656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG1 NOTCH3

3.63e-052115214702043
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG1 NOTCH3

3.99e-052215221750033
Pubmed

An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.

JAG1 NOTCH3

3.99e-052215229140246
Pubmed

Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.

JAG1 NOTCH3

4.37e-052315228036337
Pubmed

Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade.

JAG1 NOTCH3

4.37e-052315231789590
Pubmed

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.

JAG1 NOTCH3

4.37e-052315236239412
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG1 NOTCH3

4.37e-052315214701881
InteractionFBLN1 interactions

SKIL AGRP NOTCH3

1.10e-04129153int:FBLN1
InteractionOXT interactions

KMT2A ITGB7

1.18e-0422152int:OXT
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2A SUV39H2

1.23e-043492487
CoexpressionTRAVAGLINI_LUNG_VASCULAR_SMOOTH_MUSCLE_CELL

CRIM1 JAG1 NOTCH3

5.35e-0661153M41672
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG1 NOTCH3

3.65e-0516152M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG1 NOTCH3

3.65e-0516152MM1296
CoexpressionJONES_OVARY_PERICYTE

CRIM1 JAG1 NOTCH3

1.19e-04172153M48351
CoexpressionHALLMARK_NOTCH_SIGNALING

JAG1 NOTCH3

1.50e-0432152M5903
CoexpressionNABA_ECM_GLYCOPROTEINS

CRIM1 VWCE KCP

1.62e-04191153MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

CRIM1 VWCE KCP

1.75e-04196153M3008
CoexpressionLIU_CDX2_TARGETS_UP

JAG1 NOTCH3

1.80e-0435152M16637
CoexpressionNABA_MATRISOME

CRIM1 VWCE VWC2L KCP MUC5B

1.81e-041008155MM17056
CoexpressionGSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN

VWC2L KCP SUV39H2

1.86e-04200153M9356
CoexpressionGSE17721_LPS_VS_CPG_8H_BMDC_UP

CRIM1 SKIL KMT2A

1.86e-04200153M4003
CoexpressionNABA_MATRISOME

CRIM1 VWCE VWC2L KCP MUC5B

1.97e-041026155M5889
CoexpressionJONES_OVARY_MAST_CELL

CRIM1 JAG1

3.26e-0447152M48356
CoexpressionWANG_BARRETTS_ESOPHAGUS_UP

MUC5B FCGBP

3.99e-0452152M6225
CoexpressionIKEDA_MIR1_TARGETS_UP

CRIM1 JAG1

4.30e-0454152MM927
CoexpressionIKEDA_MIR1_TARGETS_UP

CRIM1 JAG1

4.30e-0454152M2372
CoexpressionNABA_CORE_MATRISOME

CRIM1 VWCE KCP

4.49e-04270153MM17057
CoexpressionTABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING

LRRC58 SKIL ITGB7

4.59e-04272153MM3825
CoexpressionNABA_CORE_MATRISOME

CRIM1 VWCE KCP

4.73e-04275153M5884
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

CRIM1 KCP JAG1 NOTCH3

4.98e-072001548c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

CRIM1 JAG1 NOTCH3

1.87e-051581538d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CRIM1 JAG1 NOTCH3

1.95e-0516015329c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5B NOTCH3 FCGBP

1.98e-05161153bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AGRP JAG1 NOTCH3

2.13e-05165153f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellClub_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MUC5B NOTCH3 FCGBP

2.21e-05167153dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

AGRP JAG1 NOTCH3

2.37e-05171153e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CRIM1 JAG1 NOTCH3

2.42e-05172153c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

CRIM1 KCP NOTCH3

2.42e-05172153858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC5B NOTCH3 FCGBP

2.50e-051741537d2f802f493f19a068e097b2909a9000e2160266
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP JAG1 FCGBP

2.50e-05174153a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 SUV39H2 NOTCH3

2.54e-0517515315c69dd5635c9251c535f1e22467712e9667ae92
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 JAG1 NOTCH3

2.68e-05178153066dbc4cc2083c549d98122ed44707127f34d582
ToppCellClub_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5B NOTCH3 FCGBP

2.68e-05178153be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC58 JAG1 NOTCH3

2.86e-05182153da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCellCerebellum-Endothelial-MURAL|Cerebellum / BrainAtlas - Mouse McCarroll V32

LRRC58 JAG1 NOTCH3

2.86e-05182153b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRIM1 KCP NOTCH3

2.91e-051831538a799807fbf24456a9811e0c64068187940a2f71
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

CRIM1 KCP NOTCH3

2.91e-05183153fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRIM1 KCP NOTCH3

2.95e-05184153327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

CRIM1 JAG1 NOTCH3

3.00e-051851534905adaeeffd353e089578e5ea614437dbe794e6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRIM1 JAG1 NOTCH3

3.05e-051861534780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 KCP NOTCH3

3.10e-05187153fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

CRIM1 KCP NOTCH3

3.10e-0518715362759efb660179402fb574ce5701c89a2e17bcfe
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

CRIM1 JAG1 NOTCH3

3.10e-05187153464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 KCP NOTCH3

3.15e-05188153ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|343B / Donor, Lineage, Cell class and subclass (all cells)

MUC5B NOTCH3 FCGBP

3.20e-05189153b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|343B / Donor, Lineage, Cell class and subclass (all cells)

MUC5B NOTCH3 FCGBP

3.20e-05189153a8246acf31f02c85421268245afb651aa8788f14
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIM1 JAG1 NOTCH3

3.20e-05189153d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 JAG1 NOTCH3

3.25e-05190153d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell(7)_Epithelial-G_(Club-Clara_cells)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MUC5B NOTCH3 FCGBP

3.25e-05190153593fd1451038b155826a48de4caa38f44406d0b9
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

CRIM1 JAG1 NOTCH3

3.30e-05191153fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MUC5B NOTCH3 FCGBP

3.35e-05192153c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCellMatrixFB-Fibroblast-D_(Pericyte)|MatrixFB / shred on cell class and cell subclass (v4)

CRIM1 JAG1 NOTCH3

3.35e-05192153630444302511f511ec6976bc045a3b4b9d8d4547
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 KCP NOTCH3

3.35e-05192153158cc5736f154da1cb3186ffbf186eae10483e48
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 KCP NOTCH3

3.35e-05192153f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MUC5B NOTCH3 FCGBP

3.40e-051931538ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MUC5B NOTCH3 FCGBP

3.40e-051931530e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCellCOPD-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

MUC5B NOTCH3 FCGBP

3.46e-0519415372a2e0cba171ab59aa176e91a59a54c562af0390
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

CRIM1 JAG1 NOTCH3

3.46e-051941533892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LRRC58 JAG1

3.46e-05194153e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCell15-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

CRIM1 JAG1 NOTCH3

3.46e-051941535c1218d239c88082496924653ed2a092dc44a906
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LRRC58 JAG1

3.46e-051941534b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MUC5B NOTCH3 FCGBP

3.51e-05195153b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIM1 JAG1 NOTCH3

3.51e-051951535dc874641ad9537e4c1369825c1fb0a59f12a83d
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC5B NOTCH3 FCGBP

3.56e-0519615391a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC5B NOTCH3 FCGBP

3.56e-05196153e819088a74d29e958371aa851ac9c74ec55367b7
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC5B NOTCH3 FCGBP

3.56e-05196153e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CRIM1 JAG1 NOTCH3

3.56e-051961531d94cecd378a829dd8014fc086d7fca48c953a91
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC5B NOTCH3 FCGBP

3.56e-05196153a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CRIM1 JAG1 NOTCH3

3.56e-05196153aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIM1 JAG1 NOTCH3

3.62e-051971534d63a274828ebb951db78421c2823453d862cd49
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIM1 JAG1 NOTCH3

3.62e-0519715315a08b04acb1cb7e84aeb072c650ce07374181f5
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MUC5B NOTCH3 FCGBP

3.62e-051971534cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCelldistal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRIM1 JAG1 NOTCH3

3.67e-0519815337ce7b485ffb207e75afd1b576b486c6d59fc136
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B NOTCH3 FCGBP

3.67e-05198153fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 JAG1 NOTCH3

3.67e-0519815377288df94286382170a266474ab85960519e8449
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 JAG1 NOTCH3

3.67e-051981532ee195f20a4f91fa1dcad9eaf96d6086e3b0fb4a
ToppCell(2)_MNPs-(2)_Dendritic_Cells|(2)_MNPs / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

SKIL ITGB7 FCGBP

3.67e-051981534c1f155298b7d0afddfeb2744b369a1ffd823916
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CRIM1 JAG1 NOTCH3

3.73e-051991539a08c25bb4851ad4ac9db8916422280f71378c2c
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B NOTCH3 FCGBP

3.73e-051991532b357cc08c425a58d45aa6c086101c8fff53e218
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRIM1 KCP NOTCH3

3.73e-05199153929f809579368201331d9099d8904b6e3c41797b
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CRIM1 JAG1 NOTCH3

3.73e-051991532ed10c5e15c9d5ed0a8bea580842348d5698a07b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

LRRC58 KMT2A NOTCH3

3.73e-05199153358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5AC+_High|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MUC5B NOTCH3 FCGBP

3.73e-05199153a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRIM1 KCP NOTCH3

3.73e-05199153854628ce91068093c14bd4d45ba38c41469f3549
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5B+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MUC5B NOTCH3 FCGBP

3.73e-051991534ab45996e6bca406c77895a5998982b8ab1cf210
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CRIM1 KCP NOTCH3

3.79e-05200153b5b5a32925f225610fe25a021a742d6397162863
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B NOTCH3 FCGBP

3.79e-05200153b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRIM1 KCP NOTCH3

3.79e-052001534e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CRIM1 KCP NOTCH3

3.79e-05200153cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CRIM1 JAG1 NOTCH3

3.79e-05200153c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

CRIM1 KCP NOTCH3

3.79e-05200153bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellClub-club-11|World / Class top

MUC5B FCGBP

1.53e-0455152d1d832e1c98a89e2b461127922c3e4d7f42d7401
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

2.54e-04711522220e1b02baa71961cfc85536bafeb313e588bf3
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

2.54e-0471152cc5de8bbcfefa2bf93cc137c74b49a745d5da229
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a8.Fezf2-Slc17a8_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VWCE AGRP

2.62e-0472152e3f4d1df43cc41b0424f27485a00ddca9e905f95
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Tmsb4x_(Tmsb4x)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGB7 MUC5B

3.73e-0486152db67c05c876a5649371c0dc6c941cc371bc2feb8
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Tmsb4x_(Tmsb4x)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGB7 MUC5B

3.73e-04861522778446e035c5585bce28ed0ef93b87b6ad90c6e
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Thalamus / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

3.82e-04871525d1dbbd86d82cbce4f2a3365242eb92d9c821a9e
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

3.82e-04871520c3a3ed1f279ed29a0113cc73ae590157a4b7334
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2|Thalamus / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

3.82e-0487152a93dbe73b337cc2d93208822728b9badf30b6870
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Thalamus / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

3.82e-048715245ef27ba84f731e4b2188813cd6931950e5164ac
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

VWC2L AGRP

4.55e-0495152ffbf3e362384c87b9db690ed39cd215e1f68375c
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)|Striatum / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

4.84e-049815226250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

4.84e-049815242875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2|Striatum / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

4.84e-04981527a62a77ca83153dacff4d02d6e32104227d0980d
ToppCell(05)_Secretory-(1)_GFP|(05)_Secretory / shred by cell type by condition

MUC5B FCGBP

5.04e-04100152838340a2b7c76f603e0ef2fe4fd170bd0dbce685
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGB7 FCGBP

5.34e-04103152287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B FCGBP

5.87e-0410815275d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2L KCP

5.87e-04108152fcc26843a8788f0fe3cec14dcae083830da80b8f
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2L KCP

5.87e-04108152c1c68e328fdf5216f23845b4de9a3b1bbe61b11c
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B FCGBP

5.87e-041081529c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGB7 MUC5B

6.09e-04110152ee45592e936d32881c0f3429c21360670e5b3ce3
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGB7 MUC5B

6.09e-04110152b9c8014fd2820e5ea28a7e02fd24227b99e71eb3
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP NOTCH3

6.65e-041151527a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP NOTCH3

6.65e-04115152c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP NOTCH3

6.65e-04115152ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellfacs-Skin-nan-24m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP FCGBP

7.36e-0412115280c79ce48664f65909ba1d167cc7bfcfedeef520
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWCE SUV39H2

8.75e-041321526f711fe84135406a8114a898a14c5ea0dfad74f2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCP FCGBP

9.55e-041381522e46d546ad962aa0fde5b1c18c2a5370a4424e9f
ComputationalTrachea genes.

CRIM1 MUC5B NOTCH3 FCGBP

3.82e-04415104MODULE_6
ComputationalPlacenta genes.

CRIM1 JAG1 NOTCH3 FCGBP

5.80e-04463104MODULE_38
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JAG1 NOTCH3

9.32e-0450102GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PERICYTE_LIKE
DiseaseCarcinoma, Pancreatic Ductal

JAG1 NOTCH3

5.74e-0524142C0887833
DiseaseGlioblastoma

JAG1 NOTCH3

6.31e-0479142C0017636
DiseaseGiant Cell Glioblastoma

JAG1 NOTCH3

7.13e-0484142C0334588
Diseasedepressive symptom measurement

VWC2L KMT2A ZPBP

9.66e-04426143EFO_0007006
Diseaseinsomnia measurement

VWC2L KMT2A ZPBP

1.08e-03443143EFO_0007876
DiseaseGlioblastoma Multiforme

JAG1 NOTCH3

1.24e-03111142C1621958
Diseasephysical activity measurement

CRIM1 VWC2L

5.85e-03245142EFO_0008002
DiseaseLung Neoplasms

JAG1 NOTCH3

6.81e-03265142C0024121
DiseaseMalignant neoplasm of lung

JAG1 NOTCH3

6.86e-03266142C0242379
Diseasecancer (implicated_via_orthology)

ITGB7 NOTCH3

6.96e-03268142DOID:162 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GQQVPCCDPCATCYC

AGRP

96

O00253
NDAGACVPAQECPCY

MUC5B

741

Q9HC84
CVDGVNTYNCQCPPE

NOTCH3

251

Q9UM47
CPNPKCGGVYFDCCV

LRRC58

296

Q96CX6
YGALCDQCPGCKTPC

ITGB7

631

P26010
PAVCEGPCVEGCQCD

FCGBP

1976

Q9Y6R7
CPGSIVQGVCGCCYT

CRIM1

51

Q9NZV1
GQCPGCQVPEDCGVC

KMT2A

1156

Q03164
IDYCEPNPCQNGAQC

JAG1

526

P78504
YVQPDAPCIQCLECC

SKIL

281

P12757
IPGQCCPVCDGCEYQ

KCP

361

Q6ZWJ8
RQGPCCPSCDGCLYQ

KCP

716

Q6ZWJ8
IYECNSRCQCGPDCP

SUV39H2

226

Q9H5I1
PDGECCPVCRDCNYE

VWCE

676

Q96DN2
CPECCVICSPGSYNP

ZPBP

316

Q9BS86
CVCALDGPVCDQPEC

VWC2L

76

B2RUY7