Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phospholipase activator activity	ARHGAP6 CCL3L1 CCL5	5.57e-05	23	65	3	GO:0016004
GeneOntologyMolecularFunction	lipase activator activity	ARHGAP6 CCL3L1 CCL5	9.11e-05	27	65	3	GO:0060229
GeneOntologyMolecularFunction	hydroperoxy icosatetraenoate dehydratase activity	CYP1A1 CYP1A2	2.17e-04	7	65	2	GO:0106256
GeneOntologyMolecularFunction	cobalt ion binding	MYT1L EPAS1	2.88e-04	8	65	2	GO:0050897
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP1A1 CYP1A2	2.88e-04	8	65	2	GO:0101021
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP1A1 CYP1A2	5.63e-04	11	65	2	GO:0101020
GeneOntologyMolecularFunction	SH2 domain binding	DAB1 TRPV4 FGFR1	6.49e-04	52	65	3	GO:0042169
GeneOntologyMolecularFunction	CCR1 chemokine receptor binding	CCL3L1 CCL5	6.74e-04	12	65	2	GO:0031726
GeneOntologyMolecularFunction	CCR5 chemokine receptor binding	CCL3L1 CCL5	7.95e-04	13	65	2	GO:0031730
GeneOntologyBiologicalProcess	positive regulation of phospholipase activity	ARHGAP6 CCL5 FGFR1	1.06e-05	14	65	3	GO:0010518
GeneOntologyBiologicalProcess	regulation of phospholipase activity	ARHGAP6 CCL5 FGFR1	4.41e-05	22	65	3	GO:0010517
GeneOntologyBiologicalProcess	positive regulation of lipase activity	ARHGAP6 CCL5 FGFR1	6.54e-05	25	65	3	GO:0060193
GeneOntologyBiologicalProcess	dibenzo-p-dioxin metabolic process	CYP1A1 CYP1A2	9.72e-05	5	65	2	GO:0018894
GeneOntologyBiologicalProcess	regulation of parathyroid hormone secretion	FGFR1 GNAS	9.72e-05	5	65	2	GO:2000828
GeneOntologyBiologicalProcess	multicellular organismal-level water homeostasis	TRPV4 AKAP11 NFAT5	1.82e-04	35	65	3	GO:0050891
GeneOntologyBiologicalProcess	multicellular organismal-level chemical homeostasis	TRPV4 AKAP11 NFAT5 EPAS1	1.87e-04	90	65	4	GO:0140962
GeneOntologyBiologicalProcess	parathyroid hormone secretion	FGFR1 GNAS	2.03e-04	7	65	2	GO:0035898
GeneOntologyCellularComponent	sperm midpiece	FSIP2 PCDH11Y PCDH11X TACR3	4.42e-05	64	64	4	GO:0097225
HumanPheno	Short metatarsal	FLNB TRPV4 FGFR1 GNAS	8.33e-05	62	20	4	HP:0010743
HumanPheno	Short tubular bones of the hand	FLNB TRPV4	8.75e-05	4	20	2	HP:0001248
HumanPheno	Short-trunked dwarfism	FLNB TRPV4	8.75e-05	4	20	2	HP:0003500
HumanPheno	Aplasia/Hypoplasia of metatarsal bones	FLNB TRPV4 FGFR1 GNAS	1.07e-04	66	20	4	HP:0001964
HumanPheno	Abnormality of the humerus	FLNB TRPV4 FGFR1 GNAS	1.20e-04	68	20	4	HP:0003063
HumanPheno	Subcortical cerebral atrophy	ESPN PDZD7 FGFR1	1.43e-04	27	20	3	HP:0012157
HumanPheno	Short middle phalanx of toe	TRPV4 FGFR1	1.45e-04	5	20	2	HP:0003795
Domain	Cyt_P450_E_grp-I_CYP1	CYP1A1 CYP1A2	1.12e-05	2	63	2	IPR008066
Domain	Protocadherin	PCDH11Y PCDH11X	1.11e-04	5	63	2	PF08374
Domain	Protocadherin	PCDH11Y PCDH11X	1.11e-04	5	63	2	IPR013585
Pathway	REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET	CYP1A1 CYP1A2	1.80e-04	7	42	2	MM14856
Pathway	REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET	CYP1A1 CYP1A2	2.40e-04	8	42	2	M27135
Pathway	REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE	CYP1A1 CYP1A2	3.08e-04	9	42	2	M27143
Pathway	PID_RHOA_REG_PATHWAY	ARHGAP6 ARHGEF12 ARHGEF17	3.41e-04	46	42	3	M68
Pathway	WP_FATTY_ACID_OMEGAOXIDATION	CYP1A1 CYP1A2	3.84e-04	10	42	2	MM15833
Pathway	WP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY	FOSB FGFR1 EPAS1	4.37e-04	50	42	3	M48087
Pathway	REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE	CYP1A1 CYP1A2	4.69e-04	11	42	2	MM14863
Pathway	REACTOME_SUMOYLATION_OF_IMMUNE_RESPONSE_PROTEINS	TOPORS EIF2AK2	5.61e-04	12	42	2	M27404
Pathway	WP_ESTROGEN_RECEPTOR_PATHWAY	CYP1A1 CYP1A2	6.62e-04	13	42	2	M39496
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY	ARHGEF12 CCL5	6.62e-04	13	42	2	M47547
Pathway	WP_FATTY_ACID_OMEGAOXIDATION	CYP1A1 CYP1A2	8.88e-04	15	42	2	M39717
Pathway	BIOCARTA_RACC_PATHWAY	TRPV4 GNAS	8.88e-04	15	42	2	M22002
Pubmed	Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.	CYP1A1 CYP1A2	3.44e-06	2	65	2	25680282
Pubmed	Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.	CYP1A1 CYP1A2	3.44e-06	2	65	2	2425809
Pubmed	The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modern Homo sapiens.	PCDH11Y PCDH11X	3.44e-06	2	65	2	23600975
Pubmed	Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.	CYP1A1 CYP1A2	3.44e-06	2	65	2	25703676
Pubmed	Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.	CYP1A1 CYP1A2	3.44e-06	2	65	2	3000715
Pubmed	A comparative analysis of the pig, mouse, and human PCDHX genes.	PCDH11Y PCDH11X	3.44e-06	2	65	2	15112107
Pubmed	Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.	CYP1A1 CYP1A2	3.44e-06	2	65	2	12147246
Pubmed	Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.	CYP1A1 CYP1A2	3.44e-06	2	65	2	17852022
Pubmed	Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes.	CYP1A1 CYP1A2	3.44e-06	2	65	2	4054433
Pubmed	Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.	CYP1A1 CYP1A2	3.44e-06	2	65	2	31147315
Pubmed	Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice.	CYP1A1 CYP1A2	3.44e-06	2	65	2	8001243
Pubmed	Metabolism of 4-n-nonylphenol by non-modified and CYP1A1- and CYP1A2-transgenic cell cultures of tobacco.	CYP1A1 CYP1A2	3.44e-06	2	65	2	16402549
Pubmed	The effect of CYP1A1 and CYP1A2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.	CYP1A1 CYP1A2	3.44e-06	2	65	2	24443269
Pubmed	Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.	CYP1A1 CYP1A2	3.44e-06	2	65	2	14980704
Pubmed	Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.	CYP1A1 CYP1A2	3.44e-06	2	65	2	16426572
Pubmed	Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains.	PCDH11Y PCDH11X	3.44e-06	2	65	2	22744706
Pubmed	Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.	PCDH11Y PCDH11X	3.44e-06	2	65	2	11003707
Pubmed	Pcdh11x Negatively Regulates Dendritic Branching.	PCDH11Y PCDH11X	3.44e-06	2	65	2	25687328
Pubmed	The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population.	CYP1A1 CYP1A2	3.44e-06	2	65	2	33046100
Pubmed	Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues.	CYP1A1 CYP1A2	3.44e-06	2	65	2	7781742
Pubmed	Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.	CYP1A1 CYP1A2	3.44e-06	2	65	2	11207026
Pubmed	Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.	CYP1A1 CYP1A2	3.44e-06	2	65	2	3785172
Pubmed	Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4.	CYP1A1 CYP1A2	3.44e-06	2	65	2	3860967
Pubmed	Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.	CYP1A1 CYP1A2	3.44e-06	2	65	2	16609368
Pubmed	CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.	CYP1A1 CYP1A2	3.44e-06	2	65	2	19276377
Pubmed	Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.	CYP1A1 CYP1A2	3.44e-06	2	65	2	15094312
Pubmed	Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).	CYP1A1 CYP1A2	3.44e-06	2	65	2	17052995
Pubmed	Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture.	CYP1A1 CYP1A2	3.44e-06	2	65	2	1335375
Pubmed	Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.	CYP1A1 CYP1A2	3.44e-06	2	65	2	8095225
Pubmed	CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines.	CYP1A1 CYP1A2	3.44e-06	2	65	2	19285097
Pubmed	A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.	CYP1A1 CYP1A2	3.44e-06	2	65	2	16505155
Pubmed	[Association of polymorph variants of CYP1A2 and CYP1A1 genes with reproductive and thyroid diseases in female workers of petrochemical industry].	CYP1A1 CYP1A2	3.44e-06	2	65	2	22855999
Pubmed	Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene.	CYP1A1 CYP1A2	3.44e-06	2	65	2	12438513
Pubmed	Quantitative analysis of alternative transcripts of human PCDH11X/Y genes.	PCDH11Y PCDH11X	3.44e-06	2	65	2	19859901
Pubmed	Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2.	CYP1A1 CYP1A2	3.44e-06	2	65	2	8274012
Pubmed	Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.	CYP1A1 CYP1A2	3.44e-06	2	65	2	1452456
Pubmed	Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.	PCDH11Y PCDH11X	3.44e-06	2	65	2	22592879
Pubmed	Amino-terminal sequence and structure of monoclonal antibody immunopurified cytochromes P-450.	CYP1A1 CYP1A2	3.44e-06	2	65	2	3718958
Pubmed	Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.	CYP1A1 CYP1A2	3.44e-06	2	65	2	14637164
Pubmed	Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.	PCDH11Y PCDH11X	3.44e-06	2	65	2	14727141
Pubmed	Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment.	CYP1A1 CYP1A2	3.44e-06	2	65	2	16516144
Pubmed	Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.	CYP1A1 CYP1A2	3.44e-06	2	65	2	21262253
Pubmed	Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.	CYP1A1 CYP1A2	3.44e-06	2	65	2	28698457
Pubmed	Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells.	CYP1A1 CYP1A2	3.44e-06	2	65	2	26953171
Pubmed	Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.	CYP1A1 CYP1A2	3.44e-06	2	65	2	18493746
Pubmed	[Association of cytochrome P450 genes polymorphisms (CYP1A1 and CYP1A2) with the development of chronic obstructive pulmonary disease in Bashkortostan].	CYP1A1 CYP1A2	3.44e-06	2	65	2	18389617
Pubmed	Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2.	CYP1A1 CYP1A2	3.44e-06	2	65	2	32726451
Pubmed	A shuffled CYP1A library shows both structural integrity and functional diversity.	CYP1A1 CYP1A2	3.44e-06	2	65	2	17823232
Pubmed	Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.	PCDH11Y PCDH11X	3.44e-06	2	65	2	21276771
Pubmed	Isolation and characterization of full-length mouse cDNA and genomic clones of 3-methylcholanthrene-inducible cytochrome P1-450 and P3-450.	CYP1A1 CYP1A2	3.44e-06	2	65	2	6548461
Pubmed	Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.	CYP1A1 CYP1A2	3.44e-06	2	65	2	3988744
Pubmed	CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.	CYP1A1 CYP1A2	3.44e-06	2	65	2	26643992
Pubmed	Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer.	CYP1A1 CYP1A2	3.44e-06	2	65	2	34242741
Pubmed	Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.	CYP1A1 CYP1A2	3.44e-06	2	65	2	10623596
Pubmed	Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.	CYP1A1 CYP1A2	3.44e-06	2	65	2	22949628
Pubmed	Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.	CYP1A1 CYP1A2	3.44e-06	2	65	2	21081470
Pubmed	Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.	PCDH11Y PCDH11X	3.44e-06	2	65	2	16874762
Pubmed	PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.	PCDH11Y PCDH11X	3.44e-06	2	65	2	16825765
Pubmed	Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity.	CYP1A1 CYP1A2	3.44e-06	2	65	2	9295056
Pubmed	In situ hybridization of Cyp1a1, Cyp1a2 and Ah receptor mRNAs expressed in murine ocular tissues.	CYP1A1 CYP1A2	1.03e-05	3	65	2	8795463
Pubmed	Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.	CYP1A1 CYP1A2	1.03e-05	3	65	2	17997381
Pubmed	Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample.	CYP1A1 CYP1A2	1.03e-05	3	65	2	24926919
Pubmed	Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.	CYP1A1 CYP1A2	1.03e-05	3	65	2	15643613
Pubmed	Contribution of CYP19A1, CYP1A1, and CYP1A2 polymorphisms in coronary heart disease risk among the Chinese Han population.	CYP1A1 CYP1A2	1.03e-05	3	65	2	35380334
Pubmed	CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD.	CYP1A1 CYP1A2	1.03e-05	3	65	2	20080081
Pubmed	Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss.	CYP1A1 CYP1A2	1.03e-05	3	65	2	15299091
Pubmed	Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer.	CYP1A1 CYP1A2	1.03e-05	3	65	2	15734958
Pubmed	Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk.	CYP1A1 CYP1A2	1.03e-05	3	65	2	24668907
Pubmed	Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan.	CYP1A1 CYP1A2	1.03e-05	3	65	2	19452301
Pubmed	Hydration and Structural Adaptations of the Human CYP1A1, CYP1A2, and CYP1B1 Active Sites by Molecular Dynamics Simulations.	CYP1A1 CYP1A2	1.03e-05	3	65	2	37511239
Pubmed	Meat intake, metabolic genes and colorectal cancer.	CYP1A1 CYP1A2	1.03e-05	3	65	2	12484238
Pubmed	Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1.	CYP1A1 CYP1A2	1.03e-05	3	65	2	38081439
Pubmed	Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.	CYP1A1 CYP1A2	1.03e-05	3	65	2	24497629
Pubmed	CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.	CYP1A1 CYP1A2	1.03e-05	3	65	2	19666078
Pubmed	The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences.	CYP1A1 CYP1A2	1.03e-05	3	65	2	6547952
Pubmed	Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.	CYP1A1 CYP1A2	1.03e-05	3	65	2	18814841
Pubmed	Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways.	CYP1A1 CYP1A2	1.03e-05	3	65	2	23956430
Pubmed	Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.	CYP1A1 CYP1A2	1.03e-05	3	65	2	21357676
Pubmed	Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.	CYP1A1 CYP1A2	1.03e-05	3	65	2	22086975
Pubmed	Adenomyosis: genetics of estrogen metabolism.	CYP1A1 CYP1A2	1.03e-05	3	65	2	30878995
Pubmed	TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw.	TRPV4 FGFR1	1.03e-05	3	65	2	30385747
Pubmed	Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.	CYP1A1 CYP1A2	1.03e-05	3	65	2	23353840
Pubmed	Differential Susceptibility to Benzo[a]pyrene Exposure during Gestation and Lactation in Mice with Genetic Variations in the Aryl Hydrocarbon Receptor and Cyp1 Genes.	CYP1A1 CYP1A2	1.03e-05	3	65	2	37755789
Pubmed	NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I.	CYP1A1 CYP1A2	1.03e-05	3	65	2	22982977
Pubmed	Genetic polymorphism of estrogen metabolizing enzymes in Siberian women with breast cancer.	CYP1A1 CYP1A2	1.03e-05	3	65	2	21977969
Pubmed	Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells.	CYP1A1 CYP1A2	1.03e-05	3	65	2	28245756
Pubmed	Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.	CYP1A1 CYP1A2	1.03e-05	3	65	2	18372398
Pubmed	Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.	CYP1A1 CYP1A2	1.03e-05	3	65	2	12398935
Pubmed	Accumulation of the nuclear dioxin (Ah) receptor and transcriptional activation of the mouse Cyp1a-1 and Cyp1a-2 genes.	CYP1A1 CYP1A2	1.03e-05	3	65	2	8215422
Pubmed	Where and what is the right shift factor or cerebral dominance gene? A critique of Francks et al. (2007).	PCDH11Y PCDH11X	1.03e-05	3	65	2	19125366
Pubmed	Regulation of cytochrome P-450 isozymes CYP1A1, CYP1A2 and CYP2B10 by three benzodioxole compounds.	CYP1A1 CYP1A2	1.03e-05	3	65	2	7750163
Pubmed	Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.	CYP1A1 CYP1A2	1.03e-05	3	65	2	24349309
Pubmed	Influence of CYP1A1/CYP1A2 and AHR polymorphisms on systemic olanzapine exposure.	CYP1A1 CYP1A2	1.03e-05	3	65	2	23492908
Pubmed	Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan.	CYP1A1 CYP1A2	1.03e-05	3	65	2	20047124
Pubmed	Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.	CYP1A1 CYP1A2	1.03e-05	3	65	2	16377763
Pubmed	Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption.	CYP1A1 CYP1A2	1.03e-05	3	65	2	22854411
Pubmed	Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes.	CYP1A1 CYP1A2	1.03e-05	3	65	2	23776235
Pubmed	Mixed-ligand copper(II) complexes activate aryl hydrocarbon receptor AhR and induce CYP1A genes expression in human hepatocytes and human cell lines.	CYP1A1 CYP1A2	1.03e-05	3	65	2	27180721
Pubmed	Non-clustered protocadherin.	PCDH11Y PCDH11X	1.03e-05	3	65	2	21173574
Pubmed	Cadherin expression in the somatosensory cortex: evidence for a combinatorial molecular code at the single-cell level.	PCDH11Y PCDH11X	1.03e-05	3	65	2	21129452
GeneFamily	Cytochrome P450 family 1	CYP1A1 CYP1A2	2.44e-05	4	37	2	1000
GeneFamily	Non-clustered protocadherins	PCDH11Y PCDH11X	2.66e-04	12	37	2	21
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ELFN1 PCDH11X AKAP11 EIF2AK2	4.96e-04	181	37	4	694
GeneFamily	PDZ domain containing	RADIL ARHGEF12 PDZD7	3.67e-03	152	37	3	1220
GeneFamily	Chemokine ligands\|Endogenous ligands	CCL3L1 CCL5	3.82e-03	45	37	2	483
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF12 ARHGEF17	8.05e-03	66	37	2	722
GeneFamily	Actins\|Deafness associated genes	ESPN PDZD7	2.24e-02	113	37	2	1152
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Tacr3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ELFN1 FOSB PCDH11X SP9 TACR3	5.60e-07	109	65	5	92ab514fd8d6711f55de9671fc80da22b20ad248
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LURAP1L ELFN1 PCDH11X SP9 TACR3	3.18e-06	155	65	5	79264ff283e36a059040a5aa9fe7337be694cb52
ToppCell	COVID-19_Severe-PLT_3\|COVID-19_Severe / Disease Group and Platelet Clusters	SECISBP2 FAM124A CCL5 GNAS VWDE	3.83e-06	161	65	5	cd4ed3fa3cd8b159ab10cf9b2ad5cd05640530d0
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	CCM2L ELFN1 FAM124A TACR3 EPAS1	4.71e-06	168	65	5	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	GAS2L1 CCM2L FAM124A FGFR1 EPAS1	7.53e-06	185	65	5	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GAS2L1 ARHGAP6 STON2 CCL5 GNAS	7.53e-06	185	65	5	0a2c8ce92a257d0ec5bcc8efa22792d53752c665
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GAS2L1 ARHGAP6 STON2 CCL5 GNAS	7.73e-06	186	65	5	4a9b5b3a56229629161d5404db2b8dd76e10cf4b
ToppCell	severe-Others\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	7.73e-06	186	65	5	234a4bc7c3529daf8804f2a366887d02a47075cd
ToppCell	severe-Others-Megakaryocytes\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	7.93e-06	187	65	5	ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCell	Multiple_Sclerosis-Other\|Multiple_Sclerosis / Disease, Lineage and Cell Type	LURAP1L GAS2L1 ARHGAP6 STON2 RNF10	7.93e-06	187	65	5	ca6f53e841fd016804e6e8ccf0199877b0e5cbdd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMG1 FOSB CCL3L1 CCL5 GNAS	8.35e-06	189	65	5	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	ESPN FOSB DUSP16 CCL5 EPAS1	8.57e-06	190	65	5	0c7eb8f4f2926af01bf44d5c9f239be7b81c67fe
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	8.79e-06	191	65	5	b9070e62e28e818631e2bbb48e097d1307777a5c
ToppCell	COVID-19_Severe-Platelet\|World / disease group, cell group and cell class	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	8.79e-06	191	65	5	b8a9fa264ce9fa14ac5e1a6c15025bb6dfe76a11
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	8.79e-06	191	65	5	960e0267786794454acbc77ddc766fd5dce99820
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1A1 FLNB APC2 TRPV4 EPAS1	9.01e-06	192	65	5	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1A1 FLNB APC2 TRPV4 EPAS1	9.01e-06	192	65	5	845cc9c18b4436b07dd3ce7980052683937546d2
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1A1 FLNB APC2 TRPV4 EPAS1	9.01e-06	192	65	5	c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell	COVID-19_Severe-Platelet\|COVID-19_Severe / disease group, cell group and cell class	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	9.24e-06	193	65	5	d9c2d2f72f9ea01e089f5d769801bcd7de4da617
ToppCell	severe_COVID-19-Platelet\|severe_COVID-19 / disease group, cell group and cell class (v2)	GAS2L1 ARHGAP6 STON2 CCL5 GNAS	9.96e-06	196	65	5	2b835fc3db81550555cbbcb3e823d9197ee35662
ToppCell	mLN-ILC-ILC\|mLN / Region, Cell class and subclass	ESPN LURAP1L GAS2L1 FOSB EPAS1	1.07e-05	199	65	5	ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCell	mLN-ILC\|mLN / Region, Cell class and subclass	ESPN LURAP1L GAS2L1 FOSB EPAS1	1.07e-05	199	65	5	d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCell	mLN-(3)_ILC\|mLN / shred on region, Cell_type, and subtype	ESPN LURAP1L GAS2L1 FOSB EPAS1	1.07e-05	199	65	5	00e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCell	mLN-(3)_ILC-(30)_ILC\|mLN / shred on region, Cell_type, and subtype	ESPN LURAP1L GAS2L1 FOSB EPAS1	1.07e-05	199	65	5	33ac6d77099076df01299be429f4ba96f2f34cc1
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MYT1L PCDH11Y PCDH11X DAB1 MEGF11	1.10e-05	200	65	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MYT1L PCDH11Y PCDH11X DAB1 MEGF11	1.10e-05	200	65	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MYT1L PCDH11Y PCDH11X DAB1 MEGF11	1.10e-05	200	65	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	COVID-19-COVID-19_Severe-Others\|COVID-19_Severe / Disease, condition lineage and cell class	GAS2L1 ARHGAP6 STON2 ARHGEF12 CCL5	1.10e-05	200	65	5	932b310a2838e4b354b90460fa904a8ebca4747a
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MYT1L PCDH11Y PCDH11X DAB1 MEGF11	1.10e-05	200	65	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	MS-Multiple_Sclerosis-Others\|Multiple_Sclerosis / Disease, condition lineage and cell class	LURAP1L GAS2L1 ARHGAP6 STON2 RNF10	1.10e-05	200	65	5	3aa674db6c3e999d8175dd1e9349c18d15ec4e9b
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MYT1L PCDH11Y PCDH11X DAB1 MEGF11	1.10e-05	200	65	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MYT1L PCDH11Y PCDH11X DAB1 MEGF11	1.10e-05	200	65	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Control-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYT1L STON2 TRPV4 RFX6	3.59e-05	127	65	4	556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Platelets-Platelets\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GAS2L1 STON2 CCL5 GNAS	5.85e-05	144	65	4	9b59a5723cb1855e0c4a83b7714535cc4de9c8e5
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Platelets\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GAS2L1 STON2 CCL5 GNAS	5.85e-05	144	65	4	e2d7547bf5152e14003aaf2713f695a153d195a1
ToppCell	MS-CD8-memory_CD4\|MS / Condition, Cell_class and T cell subcluster	APC2 CCL5 VWDE EPAS1	7.60e-05	154	65	4	aec893cf3e1cf90e18a9117183fc7a1f397425a9
ToppCell	C_02\|World / shred on cell type and cluster	ESPN FLNB DAB1 PDZD7	9.92e-05	165	65	4	a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	LURAP1L ELFN1 SP9 GNAS	1.04e-04	167	65	4	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LURAP1L ARHGAP6 RADIL STON2	1.06e-04	168	65	4	2d056cfbb470a088a0682576753535fb4528d48f
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	GAS2L1 CCM2L PCDH11Y PCDH11X	1.06e-04	168	65	4	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APC2 STON2 ARHGEF12 NIPAL3	1.09e-04	169	65	4	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	LURAP1L ELFN1 SP9 GNAS	1.09e-04	169	65	4	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	wk_20-22-Hematologic-Meg-ery-Megakaryocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GABRE GAS2L1 ARHGAP6 STON2	1.11e-04	170	65	4	eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell	Healthy_donor-MAIT\|World / disease group, cell group and cell class (v2)	FOSB DUSP16 CCL3L1 CCL5	1.16e-04	172	65	4	6524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-thrombocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LURAP1L GAS2L1 ARHGAP6 STON2	1.16e-04	172	65	4	1a9b99c7fc297d9e4b6098bf0c4fb98927a05f6d
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-thrombocytic-platelet\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LURAP1L GAS2L1 ARHGAP6 STON2	1.16e-04	172	65	4	d588ca825ab301910c1378e009b766c809b0bd5e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LURAP1L FOSB FIGN C2orf78	1.16e-04	172	65	4	107417cfab7775bc1f80807115047abfb50b7a7e
ToppCell	cellseq-Immune-Hematopoietic-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GAS2L1 ARHGAP6 STON2 CCL5	1.16e-04	172	65	4	d0c3fb48c61762dcefca858cf13c9da8eb6d0f5e
ToppCell	cellseq-Immune-Hematopoietic-Megakaryocyte/Platelet\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GAS2L1 ARHGAP6 STON2 CCL5	1.16e-04	172	65	4	eb2915165cab2660511e4b70c3a6d3ab2f770809
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	LURAP1L GAS2L1 ARHGAP6 STON2	1.24e-04	175	65	4	5ca3369ce2c2bb88ba097260195aecd67cec1a3a
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|lymph-node_spleen / Manually curated celltypes from each tissue	LURAP1L GAS2L1 ARHGAP6 STON2	1.27e-04	176	65	4	50fe3fd862dd6a6550ebb8c27f337cde468efedc
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP6 FOSB FIGN ARHGEF17	1.30e-04	177	65	4	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 PCDH11Y PCDH11X MEGF11	1.30e-04	177	65	4	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LURAP1L ARHGEF12 ARHGEF17 EPAS1	1.33e-04	178	65	4	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LURAP1L TRPV4 FAM124A SLC1A4	1.33e-04	178	65	4	6d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LURAP1L TRPV4 FAM124A SLC1A4	1.33e-04	178	65	4	d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RADIL PCDH11X FGFR1 EPAS1	1.33e-04	178	65	4	375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP6 PCDH11Y PCDH11X MEGF11	1.36e-04	179	65	4	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DAB1 NIPAL3 FIGN MEGF11	1.36e-04	179	65	4	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LURAP1L NHSL1 FLNB STON2	1.39e-04	180	65	4	c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCell	megakaryocytic-Platelet\|World / Lineage and Cell class	LURAP1L GAS2L1 ARHGAP6 STON2	1.39e-04	180	65	4	c007c3e63c2bb35ed34327dd8863899b5db93115
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYT1L CCM2L NIPAL3 EPAS1	1.39e-04	180	65	4	b35a8c6169f4b548b912af005e92ae7c6596f376
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LURAP1L ARHGAP6 FIGN ARHGEF17	1.42e-04	181	65	4	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	TRPV4 FGFR1 SLC1A4 NR1D2	1.42e-04	181	65	4	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	Healthy_donor-MAIT\|Healthy_donor / disease group, cell group and cell class (v2)	FOSB DUSP16 CCL3L1 CCL5	1.45e-04	182	65	4	ac7c83464487ecde3df6804a99551307bd768f21
ToppCell	severe_influenza-Platelet\|severe_influenza / disease group, cell group and cell class (v2)	LURAP1L GAS2L1 ARHGAP6 STON2	1.45e-04	182	65	4	2018b71ec26bf3cd7ecdc04d5473900a697cd58a
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|bone_marrow / Manually curated celltypes from each tissue	LURAP1L GAS2L1 ARHGAP6 STON2	1.45e-04	182	65	4	1a755ea44daf8447a3a1c30de7fdb9c3888bcbde
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 PDZD7 FGFR1 NIPAL3	1.45e-04	182	65	4	ccfee33de0faebbe69099d4ff3c3971f6a708b99
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS2L1 MEGF8 FAM124A NIPAL3	1.48e-04	183	65	4	3ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell	10x5'v1-week_17-19-Hematopoietic-MK-MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LURAP1L GAS2L1 ARHGAP6 CCL5	1.48e-04	183	65	4	9c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCell	control-Others\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GAS2L1 ARHGAP6 STON2 CCL5	1.51e-04	184	65	4	a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	FLNB CCM2L TRPV4 EPAS1	1.51e-04	184	65	4	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	control-Others-Megakaryocytes\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GAS2L1 ARHGAP6 STON2 CCL5	1.51e-04	184	65	4	213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCell	megakaryocytic\|World / Lineage and Cell class	LURAP1L GAS2L1 ARHGAP6 STON2	1.51e-04	184	65	4	b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.54e-04	185	65	4	9bff336510c80cd762b4e41b4570475033e709ca
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.54e-04	185	65	4	452d49c7835a4d55e41caefa44dac5cab30e7ced
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic-Megakaryocytic-Megakaryocyte\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.54e-04	185	65	4	53f5136ee1bd101dd5ac8a2c9e63b0c3b987657e
ToppCell	HSPCs-Eo/Baso_prog.\|HSPCs / Lineage and Cell class	FLNB FOSB DUSP16 STON2	1.54e-04	185	65	4	1ae29c0077bfc57e8896e59a21f20af43e7ff5b7
ToppCell	Multiple_Sclerosis-Other-Platelet\|Multiple_Sclerosis / Disease, Lineage and Cell Type	LURAP1L GAS2L1 ARHGAP6 STON2	1.54e-04	185	65	4	2e480dde7ecb2f88ff005f86ef732a1cf0209d45
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRE SKIDA1 PDZD7 FIGN	1.54e-04	185	65	4	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic-Megakaryocytic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.54e-04	185	65	4	67ac5c2bacdbdcb40ee65c44da55b3f597b410ee
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.57e-04	186	65	4	9e2e8e2c3de711734cdb4775bafb0757b4db97b1
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LURAP1L GAS2L1 ARHGAP6 STON2	1.57e-04	186	65	4	107bc473f5e57238390f8e0ab9f7263a8f93948c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.57e-04	186	65	4	8fbf5cb31192066b4c202f80baf6d7f2bdefedb9
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LURAP1L GAS2L1 ARHGAP6 STON2	1.57e-04	186	65	4	13a9ddcf93b0c4319ab9d484af5e2056e9754caa
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.57e-04	186	65	4	1dfd3fc4012bf0254adfa1f5eddadc9b6107455b
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic-Megakaryocytic\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LURAP1L GAS2L1 ARHGAP6 STON2	1.57e-04	186	65	4	49d23c985b2f5e16790f4d7ccf81ef7b794c0877
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	CCM2L ELFN1 PCDH11X EPAS1	1.57e-04	186	65	4	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SMG1 ARHGAP6 ARHGEF12 NFAT5	1.57e-04	186	65	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	FLNB PCDH11Y PCDH11X EPAS1	1.60e-04	187	65	4	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOSB FIGN ARHGEF17 EPAS1	1.60e-04	187	65	4	150023e6a50c9da461f2321074d2d5e96caafb06
ToppCell	RV-07._Pericyte\|World / Chamber and Cluster_Paper	ARHGAP6 FIGN ARHGEF17 EPAS1	1.60e-04	187	65	4	dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell	10x5'v1-week_17-19-Hematopoietic-MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LURAP1L GAS2L1 ARHGAP6 CCL5	1.60e-04	187	65	4	34cad5ac8602fe88ca3d421257190c9a388d4cb0
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB CCM2L EPAS1 MGME1	1.60e-04	187	65	4	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB CCM2L EPAS1 MGME1	1.60e-04	187	65	4	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ARHGAP6 CCL3L1 TRPV4 FGFR1	1.60e-04	187	65	4	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GABRE CCM2L FAM124A EPAS1	1.60e-04	187	65	4	03de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell	severe_influenza-Platelet\|World / disease group, cell group and cell class (v2)	LURAP1L GAS2L1 ARHGAP6 STON2	1.64e-04	188	65	4	b54632baa682aaf51100d44e7f114a54d5edd695
ToppCell	Control\|World / Disease Group and Platelet Clusters	FOSB SECISBP2 CCL5 GNAS	1.64e-04	188	65	4	f07654b215279abaf1c0882cdf41fbe31580a2ca
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GAS2L1 ARHGAP6 CCL5 GNAS	1.67e-04	189	65	4	d357fa946b9d6af46c15402f68758fb9c747bcaf
Drug	sulfaphenazole	CYP1A1 CYP1A2 FLNB TRPV4	7.54e-06	44	65	4	CID000005335
Drug	Pigment Yellow 74	CYP1A1 CYP1A2	8.03e-06	2	65	2	CID000022829
Drug	pyridoxal isonicotinoyl hydrazone	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C021079
Drug	2-methoxy-4-aminoazobenzene	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C053767
Drug	nitroaniline	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C008625
Drug	3,4,3',4'-tetrachloroazoxybenzene	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C013280
Drug	7H-dibenzo(c,g)carbazole	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C013478
Drug	2,7-dinitrofluorene	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C085049
Drug	cloflucarban	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C005055
Drug	beta-apo-8'-carotenal	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C110652
Drug	propachlor	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C011088
Drug	musk xylene	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C031447
Drug	allocryptopine	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C109505
Drug	2,7-FAA	CYP1A1 CYP1A2	8.03e-06	2	65	2	CID000009352
Drug	protopine	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C009093
Drug	sesamex	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:C100180
Drug	Canthaxanthin	CYP1A1 CYP1A2	8.03e-06	2	65	2	ctd:D016644
Drug	3-aminofluorene	CYP1A1 CYP1A2	2.40e-05	3	65	2	CID000022818
Drug	1-aminofluorene	CYP1A1 CYP1A2	2.40e-05	3	65	2	CID000022817
Drug	2,2',4,6'-tetramethoxystilbene	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C541980
Drug	2,3-diaminotoluene	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C100420
Drug	2-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C522525
Drug	6-nitrobenzo(a)pyrene	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C034699
Drug	chlortoluron	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C007033
Drug	Aminoquinolines	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:D000634
Drug	7-(deoxyadenosin-N(6)--yl)aristolactam II	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C405699
Drug	2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C519626
Drug	scutellarein	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C458179
Drug	1,2,3,7,8-pentachlorodibenzofuran	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C057584
Drug	genkwanin	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C014568
Drug	1-methoxyrutaecarpine	CYP1A1 CYP1A2	2.40e-05	3	65	2	CID005319487
Drug	Suppressor Factors, Immunologic	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:D013491
Drug	7-nitrobenzanthracene	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C038954
Drug	alyssin	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C524316
Drug	2-oxohexyl isothiocyanate	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C524315
Drug	1,2-dichloroethylene	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:C035384
Drug	Trichloroepoxypropane	CYP1A1 CYP1A2	2.40e-05	3	65	2	ctd:D014239
Drug	2,4-Dinitrophenol	CYP1A1 CYP1A2 EPAS1	3.78e-05	23	65	3	ctd:D019297
Drug	terbutryne	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C010347
Drug	1-chloropyrene	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C040345
Drug	thiacloprid	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C417209
Drug	5,5'-bis-trifluoromethyl-2,2'-dichlorobiphenyl	CYP1A1 CYP1A2	4.80e-05	4	65	2	CID000057528
Drug	purpurin	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C511975
Drug	2-nitrofluoranthene	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C049030
Drug	1,2,3,5,6,7-hexachloronaphthalene	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C575652
Drug	7-methoxyresorufin	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C076580
Drug	2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C520611
Drug	KC 500	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C477388
Drug	3-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C549241
Drug	3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C520945
Drug	tasquinimod	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C516109
Drug	musk ketone	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C031448
Drug	3,6-dinitrobenzopyrene	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C068923
Drug	3-hydroxyrutaecarpine	CYP1A1 CYP1A2	4.80e-05	4	65	2	CID000637395
Drug	sinensetin	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C059295
Drug	PY74	CYP1A1 CYP1A2	4.80e-05	4	65	2	CID000017893
Drug	N-methyl-7H-dibenzo(c,g)carbazole	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C041150
Drug	alpha-hederin	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C010177
Drug	4-aminofluorene	CYP1A1 CYP1A2	4.80e-05	4	65	2	CID000023488
Drug	Quinolinium Compounds	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:D011806
Drug	olivacine	CYP1A1 CYP1A2	4.80e-05	4	65	2	ctd:C011521
Drug	fluorene	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C041509
Drug	aflatoxin B1-DNA adduct	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C072611
Drug	2,4,6-triphenyl-1-hexene	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C533342
Drug	diphenyl	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C010574
Drug	5,12-naphthacenequinone	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C468646
Drug	6-nitrochrysene	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C035986
Drug	N-(hydroxymethyl)carbaryl	CYP1A1 CYP1A2	7.98e-05	5	65	2	CID000021341
Drug	1,2,3,4,6,7-hexachlorinated naphthalene	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C412791
Drug	furafylline	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C050131
Drug	Benz(a)Anthracenes	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:D001551
Drug	naphtho(2,3-a)pyrene	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C501268
Drug	benzyloxyresorufin	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C057754
Drug	N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C062567
Drug	4-methoxyglucobrassicin	CYP1A1 CYP1A2	7.98e-05	5	65	2	CID000656562
Drug	benzyl selenocyanate	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C054108
Drug	Uroporphyrinogens	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:D014577
Drug	glucoerucin	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C119493
Drug	bilobalide	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C073710
Drug	AC1L1SC7	CYP1A1 CYP1A2	7.98e-05	5	65	2	CID000009110
Drug	1,2,4-trihydroxy-9,10-anthracenedione	CYP1A1 CYP1A2	7.98e-05	5	65	2	ctd:C410870
Drug	NSC 255317	CYP1A1 CYP1A2 TRPV4	8.53e-05	30	65	3	CID000099644
Drug	Indican	CYP1A1 CYP1A2 EPAS1	1.04e-04	32	65	3	ctd:D007200
Drug	Lanatoside C [17575-22-3]; Up 200; 4uM; MCF7; HT_HG-U133A	CYP1A1 FOSB YTHDC2 TOPORS NFAT5	1.06e-04	164	65	5	3963_UP
Drug	4'-methoxyflavone	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C487850
Drug	7-(deoxyguanosin-N(2)-yl)aristolactam I	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C077579
Drug	acacetin	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C023717
Drug	6-NCDF	CYP1A1 CYP1A2	1.19e-04	6	65	2	CID000130492
Drug	Anthracyclines	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:D018943
Drug	2,3,4-trichlorophenol	CYP1A1 CYP1A2	1.19e-04	6	65	2	CID000027582
Drug	heptylparaben	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C481602
Drug	metamitron	CYP1A1 CYP1A2	1.19e-04	6	65	2	CID000038854
Drug	pcDd	CYP1A1 CYP1A2	1.19e-04	6	65	2	CID000037207
Drug	isosafrole	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C015959
Drug	4-hydroxychalcone	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C451019
Drug	4-hydroxybenzyl isothiocyanate	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C031364
Drug	Deoxyguanosine	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:D003849
Drug	2,3,6-trichlorophenol	CYP1A1 CYP1A2	1.19e-04	6	65	2	CID000013618
Drug	green tea extract AR25	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C465546
Drug	3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole	CYP1A1 CYP1A2	1.19e-04	6	65	2	ctd:C104750
Disease	5-hydroxy-2-methylpyridine sulfate measurement	CYP1A1 CYP1A2	4.49e-06	2	63	2	EFO_0801051
Disease	serum clozapine measurement	CYP1A1 CYP1A2	4.49e-06	2	63	2	EFO_0600041
Disease	X-21286 measurement	CYP1A1 CYP1A2	2.68e-05	4	63	2	EFO_0800804
Disease	clubfoot (is_implicated_in)	CYP1A1 FLNB	4.47e-05	5	63	2	DOID:11836 (is_implicated_in)
Disease	Chronic Obstructive Airway Disease	CYP1A1 CYP1A2 TRPV4	4.83e-05	33	63	3	C0024117
Disease	Chronic Airflow Obstruction	CYP1A1 CYP1A2 TRPV4	4.83e-05	33	63	3	C1527303
Disease	porphyria cutanea tarda (is_implicated_in)	CYP1A1 CYP1A2	6.69e-05	6	63	2	DOID:3132 (is_implicated_in)
Disease	plasma clozapine measurement	CYP1A1 CYP1A2	1.25e-04	8	63	2	EFO_0600038
Disease	advanced glycation end-product measurement	CYP1A1 CYP1A2	1.60e-04	9	63	2	EFO_0007819
Disease	theophylline measurement	CYP1A1 CYP1A2	2.00e-04	10	63	2	EFO_0021180
Disease	sweet beverage consumption measurement	CYP1A1 CYP1A2	2.00e-04	10	63	2	EFO_0010090
Disease	1,7-dimethylurate measurement	CYP1A1 CYP1A2	2.00e-04	10	63	2	EFO_0021512
Disease	coronary artery disease	CYP1A1 CYP1A2 SENP1 PCNX3 ELFN1 DAB1 ARHGEF12 FIGN NFAT5 VWDE	2.06e-04	1194	63	10	EFO_0001645
Disease	1-methylxanthine measurement	CYP1A1 CYP1A2	2.44e-04	11	63	2	EFO_0021174
Disease	plasma N-desmethylclozapine measurement	CYP1A1 CYP1A2	2.44e-04	11	63	2	EFO_0600039
Disease	5-acetylamino-6-amino-3-methyluracil measurement	CYP1A1 CYP1A2	2.44e-04	11	63	2	EFO_0800951
Disease	paraxanthine measurement	CYP1A1 CYP1A2	2.92e-04	12	63	2	EFO_0021178
Disease	renal cell carcinoma (biomarker_via_orthology)	CYP1A1 EPAS1	4.02e-04	14	63	2	DOID:4450 (biomarker_via_orthology)
Disease	1,3,7-trimethylurate measurement	CYP1A1 CYP1A2	4.63e-04	15	63	2	EFO_0021172
Disease	coffee consumption, cups of coffee per day measurement	CYP1A1 CYP1A2	5.28e-04	16	63	2	EFO_0004330, EFO_0006782
Disease	–	CCL3L1 CCL5	5.28e-04	16	63	2	609423
Disease	Susceptibility to HIV infection	CCL3L1 CCL5	5.28e-04	16	63	2	cv:C1836230
Disease	fatty liver disease (is_marker_for)	CCL5 FGFR1	5.98e-04	17	63	2	DOID:9452 (is_marker_for)
Disease	Disproportionate short stature	FLNB TRPV4 FGFR1	6.06e-04	77	63	3	C0878659
Disease	Idiopathic hypogonadotropic hypogonadism	FGFR1 TACR3	6.71e-04	18	63	2	C0342384
Disease	pulmonary hypertension (biomarker_via_orthology)	CYP1A1 TRPV4 EPAS1	6.78e-04	80	63	3	DOID:6432 (biomarker_via_orthology)
Disease	polycystic kidney disease (biomarker_via_orthology)	GNAS EPAS1	7.49e-04	19	63	2	DOID:0080322 (biomarker_via_orthology)
Disease	diet measurement, HOMA-B	DUSP16 NFAT5	7.49e-04	19	63	2	EFO_0004469, EFO_0008111
Disease	caffeine metabolite measurement	CYP1A1 CYP1A2	7.49e-04	19	63	2	EFO_0007872
Disease	serum urea measurement	CYP1A1 CYP1A2 GNAS NFAT5	8.12e-04	195	63	4	EFO_0009795
Disease	Lung Injury	CYP1A1 CYP1A2	9.18e-04	21	63	2	C0273115
Disease	Chronic Lung Injury	CYP1A1 CYP1A2	9.18e-04	21	63	2	C2350344
Disease	Infiltrating duct carcinoma of female breast	SMG1 FGFR1	9.18e-04	21	63	2	C3165106
Disease	electrocardiography	RADIL DAB1 RNF10 YTHDC2 FGFR1 EPAS1	9.33e-04	530	63	6	EFO_0004327
Disease	spontaneous preterm birth	MYT1L NHSL1 TOPORS	1.33e-03	101	63	3	EFO_0006917
Disease	sodium measurement	CYP1A1 CYP1A2 NFAT5	1.41e-03	103	63	3	EFO_0009282
Disease	response to perphenazine	MYT1L ELFN1	1.41e-03	26	63	2	GO_0097334
Disease	Kallmann Syndrome	FGFR1 TACR3	1.41e-03	26	63	2	C0162809
Disease	cystatin C measurement	CYP1A1 CYP1A2 CCM2L GNAS NFAT5	1.68e-03	402	63	5	EFO_0004617

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAAESPSATYSATFS	GNAS	536	P84996
SSSCSTPNSPEDYYT	EPAS1	476	Q99814
VTSSPAAFCSTDYSN	CDX4	101	O14627
SYSSSPEYTCRASQS	ELFN1	761	P0C7U0
QSAASRPSAYKTSSC	C2orf78	806	A6NCI8
ASSDSTPRASTVNYC	CEP44	341	Q9C0F1
SSPAYSSESECSSPS	AKAP11	301	Q9UKA4
SQDTFEACYSGTSTP	CCM2L	381	Q9NUG4
DIATCYSPRTSTESF	ARHGEF12	1321	Q9NZN5
SCSCSSSKSVTYEPD	RUBCNL	321	Q9H714
QTSSFYTDTSSPVAC	RFX6	851	Q8HWS3
SIASDPASSTSCYLE	CYP1A1	146	P04798
TFSIASDPASSSSCY	CYP1A2	146	P05177
PSSRSSSTEDFCYVF	RADIL	961	Q96JH8
CSSSSIAASYPVSRS	ARHGEF17	231	Q96PE2
SNLTEPSYSSSTCGS	FIGN	156	Q5HY92
SSSTCSLNSSENPYA	MEGF11	931	A6BM72
PTSSSSAVSEASFSY	NIPAL3	16	Q6P499
FSCRSISGSTYTPSE	MAF1	201	Q9H063
SFPSSSSSSSSSCYP	MAGEA10	51	P43363
SSGSACTSASLEPSY	NFS1	376	Q9Y697
ESAALVAFSTSSYSC	MGME1	21	Q9BQP7
SSPTSTLSNYDSCSS	ESPN	371	B1AK53
SSFCSTCSEDFTYRS	FSIP2	556	Q5CZC0
SVVSAYSAPSRFCST	FAM124A	426	Q86V42
YSLCGATPSQSDTSS	NHSL1	761	Q5SYE7
SSTETCYSAIPKASS	FLNB	2496	O75369
RYSTDSSSSTSCYSP	PCNX3	441	Q9H6A9
SSSSTSCYSPESSRG	PCNX3	446	Q9H6A9
CSYSSSSSSSTAPPA	KIAA0232	201	Q92628
SSVSSCASSAPYSSG	PDZD7	326	Q9H5P4
EPYRSSSCTSYSSCL	MEGF8	841	Q7Z7M0
SHSCPLSFSSFSYPE	GABRE	206	P78334
DSISKCSSSSSDPYS	PCDH11X	976	Q9BZA7
CSSFTTSSSPTIYST	NFAT5	81	O94916
SGSRCSSSPSAESQY	FOSB	11	P53539
FSCSSPASSSAASAK	ARHGAP6	11	O43182
DETPPCYSLSSSASS	APC2	1571	O95996
CYSLSSSASSLSEPE	APC2	1576	O95996
QPSLTCTSEAFSSYF	DAB1	466	O75553
YLSSGSFATTCESQS	EIF2AK2	176	P19525
CVTSSPSGSDTTYFS	FGFR1	101	P11362
SPCSTYLSFFSTPSE	ENTR1	206	Q96C92
PDSAYCSSSSSSSSL	GAS2L1	556	Q99501
SASYSAYSCSQLPTC	DUSP16	576	Q9BY84
ASASPYSSDTTPCCF	CCL5	21	P13501
CSSSSSYCSFPPSLS	LURAP1L	56	Q8IV03
SYCSFPPSLSSSSSS	LURAP1L	61	Q8IV03
SNCSSSSSDPYSVSD	PCDH11Y	1011	Q9BZA8
YISSSSSASSPASCH	NR1D2	11	Q14995
ATNECSSPTSSATYQ	SMG1	3521	Q96Q15
PESCSSDSESSSYSD	SKIDA1	376	Q1XH10
RSFTCSTRSAAYNPS	SENP1	56	Q9P0U3
ESSEACVFPSSAATY	SECISBP2	36	Q96T21
SASATSSFISSPYTS	TACR3	446	P29371
LASTSPTSSAFSSDY	SP9	91	P0CG40
SEDTSSPSFGCSYTD	STON2	156	Q8WXE9
LAADTPTACCFSYTS	CCL3L1	26	P16619
SYCSCSLDTAAYPSS	VWDE	621	Q8N2E2
ACSPSFSSYDCSDSY	VWDE	906	Q8N2E2
FATAFATCSSSATLP	SLC1A4	336	P43007
NSYTCSSDSALGPTS	RNF10	646	Q8N5U6
FDSDSDTFSSPFCLS	TBC1D16	226	Q8TBP0
SSLKSTDSSSYPSPC	YTHDC2	1251	Q9H6S0
SYSSGDSDVSRCSSP	TOPORS	521	Q9NS56
FPSTYLCETGFSTLS	ZBED9	1271	Q6R2W3
TYPSCRDSETFSTFL	TRPV4	656	Q9HBA0
SSYPGFSTSETTKIC	XRRA1	331	Q6P2D8
STCSSTLFLPHYASA	HECTD3	821	Q5T447
STSSYAPSSSSNLSC	MYT1L	691	Q9UL68
ASSTCSKSSFDYTHD	MYT1L	711	Q9UL68