Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	CUX2 NUMBL TPRN LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK SNAP91 DIAPH1 KEL LGR6 STRC AGRN PALLD PLXNB1 STRCP1 DNM2	2.95e-06	748	153	19	GO:0048667
GeneOntologyBiologicalProcess	neuron projection development	CUX2 FOXO6 NUMBL TPRN LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK BHLHE23 AP2A1 SNAP91 DIAPH1 KEL LGR6 STRC AGRN PALLD MYO16 PLXNB1 STRCP1 DNM2 SEZ6 TBX6	8.66e-06	1285	153	25	GO:0031175
GeneOntologyBiologicalProcess	embryonic organ development	CDX2 TPRN COL27A1 BIRC6 PALB2 ZFPM2 EPN2 HOXB3 HAND1 TBXT STRC SUFU STRCP1 FOXI1 TBX6	1.92e-05	561	153	15	GO:0048568
GeneOntologyBiologicalProcess	axonogenesis	NUMBL LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK SNAP91 DIAPH1 KEL LGR6 AGRN PALLD PLXNB1 DNM2	2.13e-05	566	153	15	GO:0007409
GeneOntologyBiologicalProcess	animal organ morphogenesis	CDX2 UNCX BCL2L11 TPRN COL27A1 SYNPO2L LAMA2 FGFRL1 BCL2 FOXI3 PALB2 ZFPM2 HOXB3 BHLHE23 ASXL3 TLE2 HAND1 TBXT LTBP3 STRC SUFU STRCP1 FOXI1 TBX6	2.13e-05	1269	153	24	GO:0009887
GeneOntologyBiologicalProcess	axon development	NUMBL LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK BHLHE23 SNAP91 DIAPH1 KEL LGR6 AGRN PALLD PLXNB1 DNM2	2.37e-05	642	153	16	GO:0061564
GeneOntologyBiologicalProcess	cell morphogenesis	CUX2 NUMBL TPRN COL27A1 LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK CDH24 SNAP91 DIAPH1 PXN KEL LGR6 STRC AGRN PALLD MYO16 PLXNB1 STRCP1 DNM2	2.43e-05	1194	153	23	GO:0000902
GeneOntologyBiologicalProcess	neuron development	CUX2 FOXO6 NUMBL TPRN LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK BHLHE23 AP2A1 SNAP91 DIAPH1 KEL FEV LGR6 STRC AGRN PALLD MYO16 PLXNB1 STRCP1 DNM2 SEZ6 TBX6	2.71e-05	1463	153	26	GO:0048666
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	CDX2 SUPT20HL2 SSBP2 ZFPM2 SBNO2 NUFIP1 HOXB3 JUND TAF3 KMT2D BHLHE23 KLF10 ASXL3 ZMIZ2 MED25 HAND1 MLLT6 TBXT FEV CHD6 USF2 AGRN IQCE FOXI1 TBX6	3.25e-05	1390	153	25	GO:0045944
GeneOntologyBiologicalProcess	synaptic vesicle endocytosis	ARPC3 AP2A1 SNAP91 CLTC DIAPH1 DNM2	8.08e-05	96	153	6	GO:0048488
GeneOntologyBiologicalProcess	transferrin transport	LMTK2 CLTC DNM2	8.38e-05	12	153	3	GO:0033572
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CUX2 NUMBL LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK SNAP91 DIAPH1 KEL LGR6 AGRN PALLD MYO16 PLXNB1 DNM2	9.83e-05	802	153	17	GO:0048812
GeneOntologyBiologicalProcess	presynaptic endocytosis	ARPC3 AP2A1 SNAP91 CLTC DIAPH1 DNM2	1.13e-04	102	153	6	GO:0140238
GeneOntologyBiologicalProcess	positive regulation of cellular component biogenesis	CUX2 BCL2L11 SYNPO2L ADGRB2 DCTN1 SLITRK1 CCK TTBK1 SNAP91 MED25 PXN PAN3 AGRN DNM2	1.14e-04	582	153	14	GO:0044089
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	CUX2 NUMBL LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK SNAP91 DIAPH1 KEL LGR6 AGRN PALLD MYO16 PLXNB1 DNM2	1.26e-04	819	153	17	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	CUX2 NUMBL LAMA2 LMTK2 BCL2 SLITRK1 SEMA4G CCK SNAP91 DIAPH1 KEL LGR6 AGRN PALLD MYO16 PLXNB1 DNM2	1.40e-04	826	153	17	GO:0048858
GeneOntologyBiologicalProcess	negative regulation of retinal cell programmed cell death	BCL2 BHLHE23	1.63e-04	3	153	2	GO:0046671
GeneOntologyBiologicalProcess	synaptic vesicle recycling	ARPC3 AP2A1 SNAP91 CLTC DIAPH1 DNM2	1.80e-04	111	153	6	GO:0036465
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	SIN3B KLF11 CUX2 CDX2 MAGEL2 HMX1 CIC ZFPM2 SBNO2 HOXB3 JUND OTP ZNF469 TAF3 KLF10 BAZ2A TLE2 MED25 MAP3K10 HAND1 TBXT SUFU TBX6	2.63e-04	1399	153	23	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	SIN3B KLF11 CUX2 CDX2 MAGEL2 HMX1 CIC ZFPM2 HOXB3 JUND OTP ZNF469 TAF3 KLF10 MED25 HAND1 TBXT SUFU TBX6	3.03e-04	1053	153	19	GO:0000122
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	SIN3B KLF11 CUX2 CDX2 MAGEL2 HMX1 CIC ZFPM2 SBNO2 HOXB3 JUND OTP ZNF469 TAF3 KLF10 BAZ2A TLE2 MED25 MAP3K10 HAND1 TBXT SUFU TBX6	3.03e-04	1413	153	23	GO:1902679
GeneOntologyBiologicalProcess	cell fate specification	FOXI3 DHH TBXT FEV SUFU TBX6	3.14e-04	123	153	6	GO:0001708
GeneOntologyBiologicalProcess	negative regulation of hyaluronan biosynthetic process	AP2A1 CLTC	3.25e-04	4	153	2	GO:1900126
GeneOntologyBiologicalProcess	behavior	CELF6 CUX2 FOXO6 BCL2 VWA1 ZZEF1 DCTN1 SLITRK1 CIC CCK TTBK1 NRXN2 ZFHX2 FEV AGRN SEZ6 BAHCC1	3.40e-04	891	153	17	GO:0007610
GeneOntologyCellularComponent	chromatin	SIN3B KLF11 CUX2 CDX2 FOXO6 UNCX SUPT20HL2 HMX1 CIC ZFPM2 NUFIP1 FANCA NKX1-2 HOXB3 JUND OTP BHLHE23 KLF10 BAZ2A ZMIZ2 ZFHX2 HAND1 TBXT FEV CHD6 USF2 FOXI1 TBX6	3.46e-06	1480	154	28	GO:0000785
GeneOntologyCellularComponent	clathrin vesicle coat	EPN3 EPN2 AP2A1 SNAP91 CLTC	8.39e-06	38	154	5	GO:0030125
GeneOntologyCellularComponent	vesicle coat	EPN3 SEC31A EPN2 AP2A1 SNAP91 CLTC	9.99e-06	67	154	6	GO:0030120
GeneOntologyCellularComponent	clathrin coat	EPN3 EPN2 AP2A1 SNAP91 CLTC	5.74e-05	56	154	5	GO:0030118
GeneOntologyCellularComponent	membrane coat	EPN3 SEC31A EPN2 AP2A1 SNAP91 CLTC	1.35e-04	106	154	6	GO:0030117
GeneOntologyCellularComponent	coated membrane	EPN3 SEC31A EPN2 AP2A1 SNAP91 CLTC	1.35e-04	106	154	6	GO:0048475
GeneOntologyCellularComponent	clathrin coat of endocytic vesicle	EPN2 AP2A1 SNAP91	1.67e-04	15	154	3	GO:0030128
GeneOntologyCellularComponent	clathrin-coated pit	EPN3 AP2A1 SNAP91 CLTC DNM2	3.13e-04	80	154	5	GO:0005905
GeneOntologyCellularComponent	endolysosome membrane	RNF167 AP2A1 CLTC	4.08e-04	20	154	3	GO:0036020
GeneOntologyCellularComponent	clathrin coat of coated pit	AP2A1 SNAP91 CLTC	4.73e-04	21	154	3	GO:0030132
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle	EPN2 AP2A1 SNAP91 CLTC DNM2	9.12e-04	101	154	5	GO:0045334
GeneOntologyCellularComponent	coated vesicle membrane	EPN3 SEC31A EPN2 AP2A1 SNAP91 CLTC SEC16A	1.09e-03	215	154	7	GO:0030662
GeneOntologyCellularComponent	endolysosome	RNF167 AP2A1 CLTC	1.38e-03	30	154	3	GO:0036019
Domain	ENTH	EPN3 EPN2 SNAP91	4.12e-05	9	150	3	PS50942
Domain	ENTH	EPN3 EPN2 SNAP91	4.12e-05	9	150	3	SM00273
Domain	ENTH	EPN3 EPN2 SNAP91	5.85e-05	10	150	3	IPR013809
Domain	ZF_PHD_2	KMT2B TAF3 KMT2D BAZ2A ASXL3 MLLT6	1.17e-04	95	150	6	PS50016
Domain	ZF_PHD_1	KMT2B TAF3 KMT2D BAZ2A ASXL3 MLLT6	1.24e-04	96	150	6	PS01359
Domain	Homeobox_CS	CUX2 CDX2 UNCX HMX1 NKX1-2 HOXB3 OTP ZFHX2	1.31e-04	186	150	8	IPR017970
Domain	Sec16_C	SEC31A SEC16A	1.91e-04	3	150	2	PF12931
Domain	ACE1_Sec16_Sec31	SEC31A SEC16A	1.91e-04	3	150	2	IPR024298
Domain	LAM_G_DOMAIN	COL27A1 LAMA2 NRXN2 AGRN	2.39e-04	38	150	4	PS50025
Domain	PHD	KMT2B TAF3 KMT2D BAZ2A MLLT6	3.43e-04	75	150	5	PF00628
Domain	Znf_PHD-finger	KMT2B TAF3 KMT2D BAZ2A MLLT6	4.37e-04	79	150	5	IPR019787
Domain	Homeobox	CUX2 CDX2 UNCX HMX1 NKX1-2 HOXB3 OTP ZFHX2	6.16e-04	234	150	8	PF00046
Domain	FYrich_C	KMT2B KMT2D	6.31e-04	5	150	2	IPR003889
Domain	FYrich_N	KMT2B KMT2D	6.31e-04	5	150	2	IPR003888
Domain	FYRC	KMT2B KMT2D	6.31e-04	5	150	2	SM00542
Domain	FYRN	KMT2B KMT2D	6.31e-04	5	150	2	SM00541
Domain	FYRN	KMT2B KMT2D	6.31e-04	5	150	2	PF05964
Domain	FYRC	KMT2B KMT2D	6.31e-04	5	150	2	PF05965
Domain	FYRC	KMT2B KMT2D	6.31e-04	5	150	2	PS51543
Domain	FYRN	KMT2B KMT2D	6.31e-04	5	150	2	PS51542
Domain	HOMEOBOX_1	CUX2 CDX2 UNCX HMX1 NKX1-2 HOXB3 OTP ZFHX2	6.52e-04	236	150	8	PS00027
Domain	HOX	CUX2 CDX2 UNCX HMX1 NKX1-2 HOXB3 OTP ZFHX2	6.70e-04	237	150	8	SM00389
Domain	EPHD	KMT2B KMT2D MLLT6	6.99e-04	22	150	3	PS51805
Domain	HOMEOBOX_2	CUX2 CDX2 UNCX HMX1 NKX1-2 HOXB3 OTP ZFHX2	7.08e-04	239	150	8	PS50071
Domain	Homeobox_dom	CUX2 CDX2 UNCX HMX1 NKX1-2 HOXB3 OTP ZFHX2	7.08e-04	239	150	8	IPR001356
Domain	PHD	KMT2B TAF3 KMT2D BAZ2A MLLT6	7.54e-04	89	150	5	SM00249
Domain	Znf_PHD	KMT2B TAF3 KMT2D BAZ2A MLLT6	8.35e-04	91	150	5	IPR001965
Domain	ENTH	EPN3 EPN2	9.41e-04	6	150	2	PF01417
Domain	TF_Brachyury	TBXT TBX6	9.41e-04	6	150	2	IPR002070
Domain	-	EPN3 EPN2 SNAP91	1.15e-03	26	150	3	1.25.40.90
Domain	Laminin_G	COL27A1 LAMA2 NRXN2 AGRN	1.21e-03	58	150	4	IPR001791
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPN3 KMT2B ZNF628 BCL2L11 PUF60 SPEG MEX3D ADGRB2 LMTK2 FGFRL1 FAM110A MBD6 FHIP1B ZZEF1 DCTN1 BIRC6 REXO1 CIC PLEKHH3 SBNO2 FANCA STK10 JUND TNRC18 KMT2D DNAJC14 KLF10 AP2A1 ZMIZ2 MCM3AP SEC16A PXN MLLT6 IRS2 LTBP3 SUFU AGRN UVRAG CEP170B SOWAHB WNK2 IQCE BAHCC1	3.12e-28	1105	156	43	35748872
Pubmed	A census of human transcription factors: function, expression and evolution.	KLF11 CUX2 CDX2 UNCX HMX1 FOXI3 CIC ZFPM2 HOXB3 JUND OTP KMT2D BHLHE23 KLF10 ZFHX2 HAND1 TBXT FEV USF2 FOXI1 TBX6	8.83e-10	908	156	21	19274049
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	CUX2 MAGEL2 IPO7 CIC STK10 ZNF469 TNRC18 ZMIZ2 CLTC MLLT6 SUFU UVRAG WNK2 IQCE FOXI1	1.17e-09	430	156	15	35044719
Pubmed	Functional proteomics mapping of a human signaling pathway.	EPN3 TTF2 KMT2B TPRN PDCD7 ZZEF1 DCTN1 EPN2 KMT2D KLF10 AP2A1 MCM3AP DIAPH1 CHD6 LTBP3 DNM2	1.17e-08	591	156	16	15231748
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SIN3B KLF11 CUX2 HMX1 BIRC6 CIC NKX1-2 JUND OTP CITED4 BAZ2A ZMIZ2 PXN ZFHX2 HAND1 TBXT USF2	2.36e-08	709	156	17	22988430
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TTF2 SIN3B KMT2B IPO7 UNCX PUF60 ARPC3 CIC PALB2 STK10 ZC3H10 JUND TNRC18 KMT2D TRIR ZMIZ2 CLTC MLLT6 USF2 DNM2 CPSF7	2.62e-08	1103	156	21	34189442
Pubmed	A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation.	CDX2 UNCX NKX1-2 TBXT TBX6	2.22e-07	30	156	5	32597756
Pubmed	Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells.	EPN2 AP2A1 CLTC	3.53e-07	4	156	3	10336464
Pubmed	Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein.	BCL2L11 MEX3D BCL2	3.53e-07	4	156	3	14769789
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SIN3B AMPD2 NUMBL PRR36 ADGRB2 SEC31A DCTN1 ARPC3 AP2A1 SNAP91 CLTC SEC16A DIAPH1 OTUD4 AGRN CEP170B WNK2 DNM2	3.66e-07	963	156	18	28671696
Pubmed	APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.	NUMBL DCTN1 AP2A1 CLTC	3.76e-07	14	156	4	29262337
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SIN3B KMT2B DCTN1 BIRC6 CIC PALB2 KMT2D ZMIZ2 SEC16A PXN IRS2 CHD6	4.60e-07	418	156	12	34709266
Pubmed	Human transcription factor protein interaction networks.	SIN3B KMT2B SSBP2 MBD6 ARPC3 CIC ZFPM2 JUND TAF3 KMT2D KLF10 ZMIZ2 SEC16A OTUD4 MLLT6 TBXT FEV CHD6 PAN3 SUFU FOXI1 CPSF7	4.66e-07	1429	156	22	35140242
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2B SSBP2 MBD6 TNRC18 TAF3 KMT2D ASXL3 ZMIZ2 MCM3AP SEC16A BAHCC1	5.98e-07	351	156	11	38297188
Pubmed	Cdx2 regulation of posterior development through non-Hox targets.	CDX2 UNCX TBXT TBX6	6.80e-07	16	156	4	19906845
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KLF11 CUX2 CDX2 CIC ZFPL1 NUFIP1 ZC3H10 CITED4 KLF10 BAZ2A ZMIZ2 PXN HAND1 MLLT6 TBXT USF2	8.04e-07	808	156	16	20412781
Pubmed	Lineage tracing of axial progenitors using Nkx1-2CreERT2 mice defines their trunk and tail contributions.	NKX1-2 TBXT TBX6	8.79e-07	5	156	3	30201686
Pubmed	Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.	AP2A1 SNAP91 CLTC	8.79e-07	5	156	3	10436022
Pubmed	TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration.	CDX2 UNCX TBXT TBX6	8.86e-07	17	156	4	35950911
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	KLF11 CUX2 CDX2 UNCX HMX1 JUND BHLHE23 KLF10 TBXT FEV USF2 FOXI1 TBX6	1.18e-06	544	156	13	28473536
Pubmed	Functional assay of effectors of ADP ribosylation factor 6 during clathrin/AP-2 coat recruitment to membranes.	AP2A1 SNAP91 CLTC	1.75e-06	6	156	3	16413285
Pubmed	Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos.	CDX2 UNCX TBXT TBX6	1.78e-06	20	156	4	19853565
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AMPD2 LMTK2 PTPN23 SEC31A ARFIP1 DCTN1 SBNO2 CHST8 CLTC SEC16A DIAPH1 OTUD4 PAN3 USF2 AGRN TAPBP PLXNB1 DNM2	1.97e-06	1084	156	18	11544199
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TTF2 AMPD2 IPO7 ZFPM2 TNRC18 KMT2D ZMIZ2 SEC16A DIAPH1 SUFU BAHCC1	2.03e-06	398	156	11	35016035
Pubmed	Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence.	CDX2 UNCX TBXT TBX6	2.20e-06	21	156	4	22675207
Pubmed	β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation.	CDX2 UNCX TBXT TBX6	2.20e-06	21	156	4	24284205
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B TBC1D2 REXO1 CIC PALB2 STK10 JUND TAF3 KMT2D BAZ2A CLTC SEC16A OTUD4 IRS2 DNM2	2.35e-06	774	156	15	15302935
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SIN3B COL27A1 PTPN23 BIRC6 SLITRK1 REXO1 SEMA4G EPN2 TNRC18 TTBK1 POM121B PALLD	2.56e-06	493	156	12	15368895
Pubmed	Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.	DCTN1 AP2A1 CLTC SEC16A	2.68e-06	22	156	4	26950368
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	IPO7 LAMA2 FAM110A SEC31A DCTN1 BIRC6 RNF167 KLF10 CLTC PXN PALLD DNM2	2.78e-06	497	156	12	23414517
Pubmed	Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis.	UNCX TBXT TBX6	3.06e-06	7	156	3	37024462
Pubmed	Primate gastrulation and early organogenesis at single-cell resolution.	CDX2 TBXT TBX6	3.06e-06	7	156	3	36517595
Pubmed	Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.	KMT2B KMT2D TBXT	3.06e-06	7	156	3	16540515
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	KLF11 KMT2B NUMBL PUF60 MBD6 CIC ZFPM2 ZC3H10 MLLT6 CHD6 AGRN WNK2 CPSF7	3.99e-06	608	156	13	16713569
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TTF2 NUMBL MEX3D SEC31A ARPC3 NUFIP1 STK10 AP2A1 MCM3AP SEC16A AGFG2 PXN OTUD4 IRS2 PAN3 UVRAG FAM83A	4.65e-06	1038	156	17	26673895
Pubmed	BRACHYURY directs histone acetylation to target loci during mesoderm development.	UNCX TBXT TBX6	4.88e-06	8	156	3	29141987
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TTF2 SIN3B NUMBL PUF60 PTPN23 ARFIP1 DCTN1 CIC GSR TRIR BAZ2A SEC16A IRS2 PLSCR3 PALLD DNM2	5.14e-06	934	156	16	33916271
Pubmed	Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.	NUMBL EPN2 AGFG2	7.29e-06	9	156	3	9303539
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	PTPN23 BIRC6 AP2A1 CLTC SEC16A	7.62e-06	60	156	5	34761192
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TTF2 SIN3B KMT2B PUF60 PTPN23 DCTN1 TAF3 KMT2D BAZ2A CLTC SEC16A PALLD	7.63e-06	549	156	12	38280479
Pubmed	Segmental border is defined by Ripply2-mediated Tbx6 repression independent of Mesp2.	UNCX TBXT TBX6	1.04e-05	10	156	3	25641698
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	IPO7 DCTN1 ARPC3 CLTC SEC16A DIAPH1 PALLD DNM2	1.18e-05	235	156	8	28378594
Pubmed	Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development.	CDX2 HAND1 TBXT	1.42e-05	11	156	3	12015300
Pubmed	MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.	CDX2 KMT2D TBXT	1.42e-05	11	156	3	37012455
Pubmed	Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development.	CDX2 HAND1 TBXT	1.42e-05	11	156	3	18794365
Pubmed	Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.	UNCX TBXT TBX6	1.42e-05	11	156	3	17584735
Pubmed	A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm.	UNCX TBXT TBX6	1.89e-05	12	156	3	34446717
Pubmed	A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production.	UNCX TBXT TBX6	1.89e-05	12	156	3	36123354
Pubmed	Involvement of the mitochondrial pathway and Bim/Bcl-2 balance in dihydroartemisinin-induced apoptosis in human breast cancer in vitro.	BCL2L11 BCL2	2.00e-05	2	156	2	23138847
Pubmed	Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells.	BCL2L11 BCL2	2.00e-05	2	156	2	25336632
Pubmed	Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer.	BCL2L11 BCL2	2.00e-05	2	156	2	23845444
Pubmed	Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice.	BCL2L11 BCL2	2.00e-05	2	156	2	22257939
Pubmed	Bcl-2 inhibits the innate immune response during early pathogenesis of murine congenital muscular dystrophy.	LAMA2 BCL2	2.00e-05	2	156	2	21850221
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	2.00e-05	2	156	2	35640156
Pubmed	Nkx1-2 is a transcriptional repressor and is essential for the activation of Brachyury in P19 mouse embryonal carcinoma cell.	NKX1-2 TBXT	2.00e-05	2	156	2	22475651
Pubmed	Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1.	KLF11 SPEG	2.00e-05	2	156	2	10973969
Pubmed	BH3-only molecule Bim mediates β-cell death in IRS2 deficiency.	BCL2L11 IRS2	2.00e-05	2	156	2	24760140
Pubmed	Genetic variants of TBX6 and TBXT identified in patients with congenital scoliosis in Southern China.	TBXT TBX6	2.00e-05	2	156	2	32672867
Pubmed	Productive entry of HIV-1 during cell-to-cell transmission via dynamin-dependent endocytosis.	SNAP91 DNM2	2.00e-05	2	156	2	23678185
Pubmed	Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.	LAMA2 AGRN	2.00e-05	2	156	2	16103356
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	2.00e-05	2	156	2	34910522
Pubmed	BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.	CDX2 TBXT	2.00e-05	2	156	2	21816365
Pubmed	Phagocytosis-induced apoptosis in macrophages is mediated by up-regulation and activation of the Bcl-2 homology domain 3-only protein Bim.	BCL2L11 BCL2	2.00e-05	2	156	2	15634885
Pubmed	Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis.	BCL2L11 BCL2	2.00e-05	2	156	2	17591857
Pubmed	A missense T (Brachyury) mutation contributes to vertebral malformations.	TBXT TBX6	2.00e-05	2	156	2	18466071
Pubmed	Dynamic transcriptional changes of TIEG1 and TIEG2 during mouse tissue development.	KLF11 KLF10	2.00e-05	2	156	2	20201061
Pubmed	Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth.	KLF11 KLF10	2.00e-05	2	156	2	9748269
Pubmed	Mixed lineage kinase 2 interacts with clathrin and influences clathrin-coated vesicle trafficking.	CLTC MAP3K10	2.00e-05	2	156	2	12105200
Pubmed	Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression.	BCL2L11 BCL2	2.00e-05	2	156	2	22081075
Pubmed	Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim.	BCL2L11 BCL2	2.00e-05	2	156	2	11709185
Pubmed	Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87.	BCL2 PXN	2.00e-05	2	156	2	25826088
Pubmed	The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins.	BCL2L11 BCL2	2.00e-05	2	156	2	19651893
Pubmed	Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.	BCL2L11 BCL2	2.00e-05	2	156	2	19805519
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	2.00e-05	2	156	2	11687802
Pubmed	Select Bcl-2 antagonism restores chemotherapy sensitivity in high-risk neuroblastoma.	BCL2L11 BCL2	2.00e-05	2	156	2	26874859
Pubmed	BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents.	BCL2L11 BCL2	2.00e-05	2	156	2	17692808
Pubmed	Bim and Bcl-2 mutually affect the expression of the other in T cells.	BCL2L11 BCL2	2.00e-05	2	156	2	17785775
Pubmed	Axl promotes cutaneous squamous cell carcinoma survival through negative regulation of pro-apoptotic Bcl-2 family members.	AXL BCL2	2.00e-05	2	156	2	21068757
Pubmed	Bcl-2-enhanced efficacy of microtubule-targeting chemotherapy through Bim overexpression: implications for cancer treatment.	BCL2L11 BCL2	2.00e-05	2	156	2	23358890
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2B KMT2D	2.00e-05	2	156	2	35506254
Pubmed	Polycystic kidney disease prevented by transgenic RNA interference.	BCL2L11 BCL2	2.00e-05	2	156	2	15818405
Pubmed	Opposing effects of bim and bcl-2 on lung endothelial cell migration.	BCL2L11 BCL2	2.00e-05	2	156	2	20656893
Pubmed	Anti-apoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts.	BCL2L11 BCL2	2.00e-05	2	156	2	19846553
Pubmed	Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer.	BCL2 PXN	2.00e-05	2	156	2	25323586
Pubmed	The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.	HAND1 TBXT TBX6	3.11e-05	14	156	3	10837126
Pubmed	Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation.	AP2A1 CLTC DNM2	3.11e-05	14	156	3	20802490
Pubmed	Redundant and nonredundant organismal functions of EPS15 and EPS15L1.	AP2A1 CLTC DNM2	3.11e-05	14	156	3	30692166
Pubmed	Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation.	SEC31A ZFPL1 INTS15	3.11e-05	14	156	3	34995116
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AMPD2 NUMBL LMTK2 CBARP CIC EPN2 KCNA7 SEC16A MAP3K10 IRS2 PAN3 UVRAG PALLD CEP170B	3.63e-05	861	156	14	36931259
Pubmed	LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.	AP2A1 SNAP91 CLTC	3.87e-05	15	156	3	21307259
Pubmed	Cdx2 is essential for axial elongation in mouse development.	CDX2 TBXT TBX6	3.87e-05	15	156	3	15136723
Pubmed	Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes.	CDX2 TBXT TBX6	4.75e-05	16	156	3	30661984
Pubmed	Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos.	CDX2 TBXT TBX6	4.75e-05	16	156	3	15057272
Pubmed	Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development.	UNCX TBXT TBX6	4.75e-05	16	156	3	24633704
Pubmed	Genomic analysis of mouse retinal development.	SIN3B KMT2B FGFRL1 SEMA4G GSR RNF167 CITED4 NRXN2 BAZ2A ARHGAP27 USF2 AGRN TAPBP SEZ6 CPSF7	5.08e-05	1006	156	15	15226823
Pubmed	Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation.	UNCX TBXT TBX6	5.75e-05	17	156	3	18045842
Pubmed	Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model.	SPEG DNM2	5.98e-05	3	156	2	35763354
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	5.98e-05	3	156	2	30801007
Pubmed	Critical role for Tbx6 in mesoderm specification in the mouse embryo.	TBXT TBX6	5.98e-05	3	156	2	12915233
Pubmed	Focal adhesion kinase, paxillin, and bcl-2: analysis of expression, phosphorylation, and association during morphogenesis.	BCL2 PXN	5.98e-05	3	156	2	10417825
Interaction	TOP3B interactions	EPN3 KMT2B ZNF628 BCL2L11 PUF60 SPEG MEX3D ADGRB2 LMTK2 FGFRL1 FAM110A MBD6 FHIP1B ZZEF1 DCTN1 BIRC6 ARPC3 REXO1 CIC PLEKHH3 SBNO2 FANCA STK10 JUND TNRC18 KMT2D DNAJC14 KLF10 AP2A1 ZMIZ2 MCM3AP SEC16A PXN OTUD4 MLLT6 IRS2 LTBP3 SUFU AGRN UVRAG CEP170B SOWAHB WNK2 IQCE BAHCC1	1.12e-16	1470	151	45	int:TOP3B
Interaction	TLE3 interactions	ATE1 CIC JUND TNRC18 KMT2D TLE2 ZMIZ2 MCM3AP AGFG2 OTUD4 MLLT6 TBXT FEV CHD6 FOXI1 CPSF7	2.44e-08	376	151	16	int:TLE3
Interaction	EPS15 interactions	EPN3 NUMBL PTPN23 EPN2 AP2A1 SNAP91 CLTC AGFG2 MLLT6 DNM2	6.43e-06	220	151	10	int:EPS15
GeneFamily	PHD finger proteins	KMT2B TAF3 KMT2D BAZ2A MLLT6	2.22e-04	90	110	5	88
GeneFamily	Ataxins\|Trinucleotide repeat containing	NUMBL TNRC18 KMT2D	4.57e-04	25	110	3	775
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	CDX2 UNCX HMX1 GJA3 OTP BHLHE23 DHH HAND1 TBXT FEV LGR6	7.57e-07	272	156	11	M1938
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	CDX2 UNCX HMX1 GJA3 OTP BHLHE23 DHH HAND1 TBXT FEV LGR6	1.08e-06	282	156	11	MM822
Coexpression	GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_UP	BCL2 SLITRK1 CIC TRIR ZMIZ2 MCM3AP AGRN TAPBP TBX6	3.19e-06	199	156	9	M9038
Coexpression	GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN	BCL2L11 PUF60 SSBP2 SLITRK1 NUFIP1 TRIR AGRN FAM8A1 CAPN15	3.32e-06	200	156	9	M9055
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	AMPD2 REXO1 CIC SBNO2 FANCA KMT2D ZMIZ2 INTS15 AGRN CAPN15 CPSF7	6.15e-06	338	156	11	M17094
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	CDX2 UNCX PRR36 HMX1 NKX1-2 HOXB3 OTP BHLHE23 DHH KCNA7 NRXN2 HAND1 TBXT FEV	1.27e-05	591	156	14	M2019
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	CDX2 UNCX PRR36 HMX1 NKX1-2 HOXB3 OTP BHLHE23 DHH KCNA7 NRXN2 HAND1 TBXT FEV	1.54e-05	601	156	14	MM866
Coexpression	GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP	TDRD9 SEC31A GSR JUND KMT2D DNAJC14 INTS15 SEC16A	2.76e-05	200	156	8	M7764
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_SMG_CELL	KLF11 NUMBL FGFRL1 PTPN23 BCL2 SBNO2 STK10 CITED4 C2CD4D AGFG2 ARHGAP27 PALLD WNK2 IQCE FAM83A	6.39e-05	775	156	15	M45713
Coexpression	IBRAHIM_NRF1_DOWN	SSBP2 PLEKHH3 HOXB3 JUND TNRC18 AGRN PLXNB1	6.60e-05	167	156	7	M42512
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	UNCX ADGRB2 HMX1 CCK BHLHE23 DHH NRXN2 TBXT CACNA1I FEV MYO16	6.66e-05	438	156	11	M1954
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	UNCX ADGRB2 HMX1 CCK BHLHE23 DHH NRXN2 TBXT CACNA1I FEV MYO16	6.93e-05	440	156	11	MM832
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	MAGEL2 LAMA2 ZBTB47 CIC THBD DHH NRXN2 LTBP3	3.42e-07	188	156	8	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPN3 TPRN CCK CHST8 ARHGAP27 CEP170B SOWAHB FAM83A	4.70e-07	196	156	8	9554ac6eb5f381bcde3ba40c32aa3fc340974540
ToppCell	(08)_Brush+PNEC-(0)_Reference\|(08)_Brush+PNEC / shred by cell type by condition	NUMBL MEX3D FAM110A PLEKHH3 RNF167 AP2A1 AGRN PLXNB1	4.88e-07	197	156	8	d500bfed2a76f7300f2f17b60962c18a40efd084
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8\|GI_large-bowel / Manually curated celltypes from each tissue	CDX2 NUMBL ZBTB47 IGFBP2 FEV LGR6 BAHCC1	2.01e-06	166	156	7	13bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPEG LAMA2 ZFPM2 HOXB3 LTBP3 LGR6 PALLD	3.08e-06	177	156	7	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFRL1 CBARP FAM110A JUND IRS2 LTBP3 PALLD	4.74e-06	189	156	7	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	SPEG COL27A1 VWA1 THBD TLE2 LGR6 PALLD	6.02e-06	196	156	7	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAPSA CUX2 FOXO6 TLE2 CLTC TAPBP	2.39e-05	163	156	6	d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPEG ZFPM2 HOXB3 LTBP3 LGR6 PALLD	2.48e-05	164	156	6	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD7 ZC3H10 MCM3AP CACNA1I KEL PAN3	2.65e-05	166	156	6	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD7 ZC3H10 MCM3AP CACNA1I KEL PAN3	2.65e-05	166	156	6	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGFBP2 ZFHX2 PLXNB1 IQCE FAM83A TBX6	3.68e-05	176	156	6	87de432c680b80555342afac864599bbc002c040
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CUX2 MAGEL2 SEMA4G TLE2 CHD6 MYO16	4.43e-05	182	156	6	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUMBL LAMA2 VWA1 DHH TMEM200C WNK2	4.86e-05	185	156	6	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFRL1 CBARP FAM110A JUND IRS2 LTBP3	5.00e-05	186	156	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_Synovial_Sarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	CUX2 CHST8 BHLHE23 KCNA7 FEV	5.09e-05	114	156	5	674d34a35f403ba938a2a109a68bf34bdc3657c9
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_Synovial_Sarcoma-3\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	CUX2 CHST8 BHLHE23 KCNA7 FEV	5.09e-05	114	156	5	cbed6161fc307056ef1ac08b0f62c8c544866884
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPN3 UNCX CHST8 GJA3 IGFBP2 LTBP3	5.16e-05	187	156	6	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCK CDH24 TLE2 PALLD TMEM200C MYO16	5.16e-05	187	156	6	d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEG COL27A1 ZFPM2 LGR6 PALLD MYO16	5.80e-05	191	156	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 SEC31A JUND CLTC SEC16A CEP170B	6.14e-05	193	156	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 SEC31A JUND CLTC SEC16A CEP170B	6.14e-05	193	156	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 SEC31A JUND CLTC SEC16A CEP170B	6.32e-05	194	156	6	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL SPEG LAMA2 ZFPM2 LGR6 PALLD	6.32e-05	194	156	6	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B FAM110A BIRC6 CCK JUND PAN3	6.50e-05	195	156	6	2c03d1a2f208b6737311458a4bd8f2e4444de29a
ToppCell	facs-Skin-Skin_Anagen\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B FAM110A BIRC6 CCK JUND PAN3	6.50e-05	195	156	6	ffd87cc7ae9b141bf48e072ea1a1420794499790
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 AXL COL27A1 LAMA2 CHST8 PALLD	6.50e-05	195	156	6	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	facs-Skin-Skin_Anagen-18m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B FAM110A BIRC6 CCK JUND PAN3	6.50e-05	195	156	6	0d37dd66a8d60fc9cda3d6e3c4fbe67e577b890e
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	AXL COL27A1 TBC1D2 ZBTB47 ZNF469 LTBP3	6.50e-05	195	156	6	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 AXL COL27A1 LAMA2 CCK PALLD	6.50e-05	195	156	6	095b8e0be385b6390420589124a95fa4ba3682ab
ToppCell	TCGA-Thryoid-Primary_Tumor\|TCGA-Thryoid / Sample_Type by Project: Shred V9	PRR36 TBC1D2 PLEKHN1 CDH24 AGRN CEP170B	6.50e-05	195	156	6	7cdee2ae90edf15e4cbcf70797b8caf1f037b0ef
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AXL LAMA2 CLTC IRS2 LTBP3 PAN3	6.50e-05	195	156	6	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma\|TCGA-Thryoid / Sample_Type by Project: Shred V9	PRR36 TBC1D2 PLEKHN1 CDH24 AGRN CEP170B	6.50e-05	195	156	6	b61b8c931bd0ca3678486653ae1d7e9915c696c7
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NUMBL LAMA2 ZFPM2 ZNF469 NRXN2 PALLD	6.69e-05	196	156	6	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSB1 IPO7 LAMA2 SEC31A IRS2 LTBP3	6.69e-05	196	156	6	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPRN CCK ARHGAP27 CEP170B SOWAHB FAM83A	6.69e-05	196	156	6	22fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL SPEG LAMA2 ZFPM2 PALLD WNK2	6.69e-05	196	156	6	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AXL SPEG LAMA2 ZFPM2 LGR6 PALLD	6.69e-05	196	156	6	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-41\|World / Primary Cells by Cluster	WSB1 TDRD9 ADGRB2 ZFPM2 CHD6 MYO16	6.69e-05	196	156	6	dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	AXL MEX3D LMTK2 FBXL17 MCM3AP CAPN15	6.69e-05	196	156	6	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSB1 IPO7 LAMA2 SEC31A IRS2 LTBP3	6.69e-05	196	156	6	9bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL SPEG LAMA2 ZFPM2 PALLD WNK2	6.69e-05	196	156	6	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Control-Endothelial-Endothelial-Activated_Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BCL2L11 FAM110A THBD IGFBP2 PXN	6.76e-05	121	156	5	a5962d1c476e6966870832b72d511607e047248b
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA4G TLE2 CEP170B WNK2 PLXNB1 DNM2	6.88e-05	197	156	6	e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA4G TLE2 CEP170B WNK2 PLXNB1 DNM2	6.88e-05	197	156	6	19cf283537c853fa902852e7b8ac1139729a931a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IPO7 AXL COL27A1 LAMA2 ZFPM2 PALLD	7.07e-05	198	156	6	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHST8 OTP SNAP91 ASXL3 WNK2 FOXI1	7.07e-05	198	156	6	e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCell	5'-Adult-Distal_Rectal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA4G TLE2 CEP170B WNK2 PLXNB1 DNM2	7.07e-05	198	156	6	db26c20321f9ab102d6484f22ddb2bde684067b1
ToppCell	mLN-ILC-ILC\|mLN / Region, Cell class and subclass	SSBP2 PLEKHN1 JUND KLF10 SNAP91 C2CD4D	7.27e-05	199	156	6	ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCell	mLN-ILC\|mLN / Region, Cell class and subclass	SSBP2 PLEKHN1 JUND KLF10 SNAP91 C2CD4D	7.27e-05	199	156	6	d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCell	mLN-(3)_ILC\|mLN / shred on region, Cell_type, and subtype	SSBP2 PLEKHN1 JUND KLF10 SNAP91 C2CD4D	7.27e-05	199	156	6	00e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCell	mLN-(3)_ILC-(30)_ILC\|mLN / shred on region, Cell_type, and subtype	SSBP2 PLEKHN1 JUND KLF10 SNAP91 C2CD4D	7.27e-05	199	156	6	33ac6d77099076df01299be429f4ba96f2f34cc1
ToppCell	11.5-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	SPEG COL27A1 THBD TLE2 LGR6 PALLD	7.27e-05	199	156	6	1a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCell	facs-Trachea-nan-3m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 AXL LAMA2 FGFRL1 SEC31A LTBP3	7.27e-05	199	156	6	67f78c070c56e44fba36542041bf7fa1c291807c
ToppCell	facs-Trachea-nan-3m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 AXL LAMA2 FGFRL1 SEC31A LTBP3	7.27e-05	199	156	6	1ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	NAPSA LTBP3 STRC CEP170B PLXNB1 DNM2	7.48e-05	200	156	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	MBD6 PLEKHN1 PXN MLLT6 LTBP3	8.19e-05	126	156	5	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
Computational	B lymphoma expression clusters.	WSB1 STK10 KLF10 ZMIZ2 SEC16A IRS2	2.93e-05	80	81	6	MODULE_358
Computational	Genes in the cancer module 262.	WSB1 STK10 KLF10 ZMIZ2 SEC16A IRS2	1.03e-04	100	81	6	MODULE_261
Drug	o-nitrophenyl beta-D-fucopyranoside	EPN3 NUMBL EPN2 AP2A1 SNAP91 CLTC DNM2	6.37e-07	74	152	7	CID000004597
Drug	Carcinine [56897-53-1]; Down 200; 22uM; PC3; HT_HG-U133A	ADGRB2 SEMA4G ZFPL1 SBNO2 JUND ZMIZ2 MED25 PXN USF2 AGRN	7.18e-07	193	152	10	4225_DN
Drug	Doxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A	AXL ADGRB2 SBNO2 JUND ZMIZ2 MED25 PXN PLSCR3 PLXNB1 CAPN15	7.88e-07	195	152	10	4235_DN
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	SIN3B KLF11 BCL2 CIC SBNO2 BAZ2A PXN PLSCR3 DNM2 CAPN15	8.65e-07	197	152	10	7201_DN
Drug	Zaprinast [37762-06-4]; Down 200; 14.8uM; PC3; HT_HG-U133A	SPEG SSBP2 ZZEF1 SBNO2 JUND MED25 PXN CACNA1I USF2	6.20e-06	193	152	9	6749_DN
Drug	Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; PC3; HT_HG-U133A	AXL ADGRB2 ZZEF1 SBNO2 JUND ZMIZ2 PXN PLXNB1 CPSF7	6.20e-06	193	152	9	4241_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A	SSBP2 SBNO2 MED25 DIAPH1 PXN OTUD4 IRS2 AGRN CAPN15	6.46e-06	194	152	9	4301_DN
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A	PRR36 CIC SBNO2 EPN2 DIAPH1 PLSCR3 USF2 PLXNB1 IQCE	7.02e-06	196	152	9	1679_DN
Drug	Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	WSB1 CUX2 BCL2 HMX1 BAZ2A MED25 TBXT CACNA1I AGRN	7.62e-06	198	152	9	5797_UP
Drug	Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; MCF7; HT_HG-U133A	BCL2 CIC SBNO2 JUND BAZ2A PXN PLSCR3 AGRN DNM2	7.94e-06	199	152	9	3435_DN
Drug	Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; MCF7; HT_HG-U133A	TTF2 CIC PXN OTUD4 PLSCR3 USF2 AGRN DNM2 CAPN15	7.94e-06	199	152	9	3273_UP
Drug	AC1L9IF6	AXL CCK OTP TBXT	1.05e-05	21	152	4	CID000445701
Drug	Ethisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A	ZZEF1 ZMIZ2 MED25 PXN USF2 AGRN CAPN15 BAHCC1	4.27e-05	190	152	8	4340_DN
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; PC3; HT_HG-U133A	ADGRB2 ZZEF1 JUND PXN USF2 AGRN PLXNB1 CAPN15	4.77e-05	193	152	8	4226_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	AXL ADGRB2 SBNO2 JUND ZMIZ2 PXN AGRN PLXNB1	4.95e-05	194	152	8	4331_DN
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; PC3; HT_HG-U133A	ADGRB2 SBNO2 JUND MED25 AGRN PLXNB1 CAPN15 CPSF7	4.95e-05	194	152	8	4246_DN
Drug	Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A	TBC1D2 CIC JUND PXN TBXT CACNA1I AGRN CAPN15	4.95e-05	194	152	8	4310_UP
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A	KMT2B CIC SBNO2 EPN2 JUND DIAPH1 USF2 CAPN15	4.95e-05	194	152	8	1699_DN
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	ADGRB2 SEMA4G SBNO2 JUND TLE2 MED25 PXN AGRN	4.95e-05	194	152	8	4335_DN
Drug	Aconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A	PRR36 SPEG TBC1D2 LAMA2 CHST8 ZMIZ2 IRS2 PLSCR3	4.95e-05	194	152	8	2776_UP
Drug	Fosfosal [6064-83-1]; Down 200; 18.4uM; PC3; HT_HG-U133A	ADGRB2 ZZEF1 JUND ZMIZ2 MED25 PXN AGRN CAPN15	4.95e-05	194	152	8	4239_DN
Drug	Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HG-U133A	TTF2 LAMA2 ZZEF1 ZMIZ2 ZFHX2 HAND1 CACNA1I USF2	5.13e-05	195	152	8	1884_UP
Drug	Gabazine [105538-73-6]; Down 200; 10.8uM; PC3; HT_HG-U133A	ZZEF1 SBNO2 JUND DIAPH1 PXN AGRN PLXNB1 CAPN15	5.32e-05	196	152	8	4236_DN
Drug	Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A	CIC SBNO2 EPN2 THBD INTS15 PXN PLSCR3 CEP170B	5.32e-05	196	152	8	3422_DN
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	WSB1 KMT2B CIC ZFPL1 STK10 JUND KLF10 IRS2	5.32e-05	196	152	8	5318_UP
Drug	Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A	LAMA2 ZZEF1 SEMA4G ZMIZ2 ZFHX2 HAND1 USF2 AGRN	5.32e-05	196	152	8	1546_UP
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; PC3; HT_HG-U133A	KMT2B JUND BAZ2A MED25 AGFG2 PXN AGRN TBX6	5.32e-05	196	152	8	4307_UP
Drug	Epitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A	SBNO2 JUND MED25 PXN AGRN DNM2 CAPN15 CPSF7	5.32e-05	196	152	8	4204_DN
Drug	Acetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT_HG-U133A	TTF2 SIN3B EPN2 JUND AGFG2 PXN USF2 IQCE	5.32e-05	196	152	8	1686_DN
Drug	Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A	WSB1 SPEG CHST8 BAZ2A ZMIZ2 TBXT CACNA1I KEL	5.52e-05	197	152	8	5046_UP
Drug	Flunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SEMA4G SBNO2 FANCA BAZ2A PLSCR3 CAPN15 FOXI1 BAHCC1	5.72e-05	198	152	8	6023_DN
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A	WSB1 KMT2B EPN2 CHST8 FANCA TLE2 IRS2 CAPN15	5.72e-05	198	152	8	5259_DN
Drug	genistein; Down 200; 10uM; MCF7; HG-U133A	SSBP2 SBNO2 ZFHX2 IRS2 PLSCR3 USF2 PLXNB1 BAHCC1	5.72e-05	198	152	8	638_DN
Drug	Iodixanol [92339-11-2]; Up 200; 2.6uM; HL60; HT_HG-U133A	SSBP2 ZZEF1 SEMA4G HOXB3 KMT2D CACNA1I PALLD PLXNB1	5.72e-05	198	152	8	3023_UP
Drug	Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A	PRR36 CIC SBNO2 STK10 TLE2 ZMIZ2 CAPN15 BAHCC1	5.72e-05	198	152	8	2797_UP
Drug	Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A	ZZEF1 DCTN1 ZFPL1 PLEKHH3 EPN2 ZMIZ2 AGRN BAHCC1	5.72e-05	198	152	8	2848_UP
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A	CIC SEMA4G IGFBP2 BAZ2A TLE2 DIAPH1 PXN KEL	5.92e-05	199	152	8	6349_UP
Drug	Niacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A	WSB1 KMT2B TBC1D2 ZMIZ2 ZFHX2 IRS2 FOXI1 BAHCC1	5.92e-05	199	152	8	3381_DN
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A	KMT2B TBC1D2 ADGRB2 LMTK2 BCL2 JUND BAZ2A ZMIZ2	5.92e-05	199	152	8	3741_DN
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A	SBNO2 ZMIZ2 MED25 PXN IRS2 AGRN PLXNB1 CAPN15	5.92e-05	199	152	8	4297_DN
Drug	estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	BCL2L11 ZFPL1 CHST8 FANCA THBD KLF10 USF2 CAPN15	5.92e-05	199	152	8	1021_UP
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	2.60e-05	2	151	2	DOID:0110471 (implicated_via_orthology)
Disease	breast carcinoma	AMPD2 CUX2 BCL2L11 LMTK2 SSBP2 BCL2 ATE1 PALB2 ZFPM2 CITED4 TTBK1 PRSS42P TBXT LGR6 ARHGAP27 BAHCC1	7.14e-05	1019	151	16	EFO_0000305
Disease	Diffuse Large B-Cell Lymphoma	BCL2 SEC31A KMT2D CLTC	1.83e-04	55	151	4	C0079744
Disease	DnaJ homolog subfamily B member 11 measurement	ZFPM2 MICA	3.85e-04	6	151	2	EFO_0801537
Disease	mean corpuscular hemoglobin concentration	CUX2 BCL2L11 AXL FBXL17 BCL2 ARFIP1 SEC16A OTUD4 CACNA1I IRS2 PAN3 USF2 MYO16 CAPN15 TBX6	5.68e-04	1105	151	15	EFO_0004528
Disease	Nonsyndromic genetic hearing loss	TPRN DIAPH1 STRC FOXI1	6.35e-04	76	151	4	cv:C5680182
Disease	Pancreatic carcinoma, familial	PALB2 PALLD	9.15e-04	9	151	2	C2931038
Disease	uveitis	TNRC18 MICA	9.15e-04	9	151	2	EFO_1001231
Disease	age at menopause	IPO7 BCL2L11 FBXL17 BIRC6 TNRC18 CHD6 TAPBP	9.66e-04	302	151	7	EFO_0004704
Disease	cataract (implicated_via_orthology)	CCK GSR GJA3	9.72e-04	38	151	3	DOID:83 (implicated_via_orthology)
Disease	Congenital small ears	HMX1 FOXI3 KMT2D	1.21e-03	41	151	3	C0152423
Disease	venous thromboembolism, von Willebrand factor measurement	TTF2 ZFPM2 MICA	1.30e-03	42	151	3	EFO_0004286, EFO_0004629
Disease	Microphthalmos	HMX1 KMT2D	1.39e-03	11	151	2	C0026010
Disease	coagulation factor XA measurement	COL27A1 FAM110A	1.39e-03	11	151	2	EFO_0020266
Disease	hearing impairment	TPRN FANCA DIAPH1 FOXI1	1.64e-03	98	151	4	C1384666
Disease	motor neuron disease (implicated_via_orthology)	VWA1 DCTN1	1.66e-03	12	151	2	DOID:231 (implicated_via_orthology)
Disease	intracranial aneurysm (is_implicated_in)	BCL2 KMT2D	1.66e-03	12	151	2	DOID:10941 (is_implicated_in)
Disease	tumor necrosis factor receptor superfamily member EDAR measurement	ZFPM2 SUFU	1.66e-03	12	151	2	EFO_0008310
Disease	dickkopf‐related protein 1 measurement	ZFPM2 SUFU	1.66e-03	12	151	2	EFO_0010620
Disease	coagulation factor X measurement	COL27A1 FAM110A	1.96e-03	13	151	2	EFO_0020265
Disease	putamen volume change measurement	TAF3 MYO16	1.96e-03	13	151	2	EFO_0021495
Disease	Alzheimer's disease (is_marker_for)	BCL2 GSR THBD IGFBP2 SNAP91 IRS2	2.14e-03	257	151	6	DOID:10652 (is_marker_for)
Disease	Medulloblastoma	PALB2 IRS2 SUFU	2.16e-03	50	151	3	C0025149
Disease	Fanconi anemia	PALB2 FANCA	2.27e-03	14	151	2	cv:C0015625
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	TPRN STRC FOXI1	2.29e-03	51	151	3	cv:CN043650
Disease	non-melanoma skin carcinoma	SBNO2 FANCA ZNF469 TAF3 C2CD4D MICA	2.50e-03	265	151	6	EFO_0009260
Disease	Lymphoma, Follicular, Grade 2	BCL2 KMT2D	2.61e-03	15	151	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	BCL2 KMT2D	2.61e-03	15	151	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	BCL2 KMT2D	2.61e-03	15	151	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	BCL2 KMT2D	2.61e-03	15	151	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	BCL2 KMT2D	2.61e-03	15	151	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	BCL2 KMT2D	2.61e-03	15	151	2	C0079758
Disease	Autosomal Recessive Centronuclear Myopathy	SPEG DNM2	2.61e-03	15	151	2	C3645536
Disease	hepcidin:transferrin saturation ratio	SLITRK1 PAN3	2.61e-03	15	151	2	EFO_0007902
Disease	mean reticulocyte volume	BCL2L11 BCL2 REXO1 SBNO2 ZNF469 KLF10 AGFG2 OTUD4 IRS2 MYO16 TBX6	2.80e-03	799	151	11	EFO_0010701
Disease	reticulocyte count	BCL2L11 FGFRL1 BCL2 FAM110A ARFIP1 BIRC6 SBNO2 NUFIP1 ZNF469 OTUD4 KEL IRS2 TBX6	2.85e-03	1045	151	13	EFO_0007986
Disease	T-Cell Lymphoma	KMT2D ASXL3	2.98e-03	16	151	2	C0079772
Disease	Huntington's disease (biomarker_via_orthology)	BCL2 GSR	2.98e-03	16	151	2	DOID:12858 (biomarker_via_orthology)
Disease	bipolar disorder	FOXO6 TDRD9 SSBP2 PALB2 KMT2D DHH SNAP91 SUFU WNK2	2.99e-03	577	151	9	MONDO_0004985
Disease	response to radiation, Urinary retention	MEX3D DNM2	3.36e-03	17	151	2	GO_0009314, HP_0000016
Disease	iritis	TNRC18 MICA	3.36e-03	17	151	2	EFO_1000997
Disease	basophil measurement	BCL2 ZNF469 MICA	3.63e-03	60	151	3	EFO_0803539
Disease	Bone marrow hypocellularity	PALB2 FANCA	3.77e-03	18	151	2	C1855710
Disease	platelet-derived growth factor BB measurement	ZFPM2 MICA SUFU	3.81e-03	61	151	3	EFO_0008264
Disease	Adenocarcinoma of prostate	PALB2 FANCA	4.65e-03	20	151	2	C0007112
Disease	Lymphoma, Follicular	BCL2 KMT2D	4.65e-03	20	151	2	C0024301
Disease	bitter alcoholic beverage consumption measurement	UNCX CIC NRXN2 BAHCC1	4.93e-03	133	151	4	EFO_0010092

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLSNALVPGGPAPPA	ADGRB2	246	O60241
GARAAPALAGTPAPP	CBARP	591	Q8N350
PALAGTPAPPAGAAR	CBARP	596	Q8N350
FPALPAALPAANGPV	MLLT6	761	P55198
QNLPPGFPASVAGPV	BAHCC1	846	Q9P281
GFPASVAGPVPSVFP	BAHCC1	851	Q9P281
GSDFLQPPQPAFPGR	CCDC117	16	Q8IWD4
NPGPPGPAATAAAEQ	CDX2	141	Q99626
VPSNPVAAPGFFIHP	BIRC6	1676	Q9NR09
PPSVQGHPFPEGAAA	CXorf49;	111	A8MYA2
PGTDAPGIPAALAFG	DCTN1	806	Q14203
FTGLPPAPAASGLKP	BAZ2A	11	Q9UIF9
GGDLPAAPAPRAPAQ	BHLHE23	46	Q8NDY6
SLQPPPGPFGAVAAA	FEV	216	Q99581
QAGAFAPQPLLPTPS	EPN3	601	Q9H201
QPQGPPPAAGAVASY	GSR	51	P00390
AQGACRGPTFAPLPP	AGRN	746	O00468
IEAGAFQGSPAPPLP	ARFIP1	61	P53367
FDGPAAQPSLGPTPE	AP2A1	686	O95782
QGPLAPPASPGPFAT	BCL2L11	61	O43521
PPFGAAAVPGTQLSP	SNAP91	866	O60641
GAPPLQSARSLPGPA	AMPD2	91	Q01433
PRAPGEPTPASFFIG	CEP170B	786	Q9Y4F5
AGALTQPVPPADPAG	CCK	16	P06307
PPFGFGVPAAPVLPF	DIAPH1	751	O60610
SGGPAQAPLPVLSPA	CUX2	751	O14529
APAGDKGFQPPSPSL	DMRTC1;	156	Q5HYR2
AAPLLPAAAANSPPG	CELF6	286	Q96J87
PPGGFAPAAINRSIP	ASXL3	1456	Q9C0F0
AAAAPTVAPGPAQPG	NUMBL	246	Q9Y6R0
QPFPAPVGPFDAAPA	NUMBL	461	Q9Y6R0
SFGPNPFLGPVPIAP	OTUD4	841	Q01804
LNPAFFPPPNATVGP	CPSF7	291	Q8N684
FLAALPDPSPSGPQA	IQCE	651	Q6IPM2
PVAGLPSAPPPQFSG	PTPN23	856	Q9H3S7
GPVQQSPHAALPPGF	INTS15	391	Q96N11
AGIFPFAPPGAAAEP	MICA	11	Q29983
PEPAPGAAFLPVLNG	CAPN15	71	O75808
VPSAPTGPGPLLEFA	FHIP1B	86	Q8N612
EFGAPPSPANFIQPG	GGT3P	431	A6NGU5
APQPAPGAAAASKPN	DNAJC14	666	Q6Y2X3
ACPLPPLAGGEAFPF	MBD6	506	Q96DN6
PLAGGEAFPFPSPEQ	MBD6	511	Q96DN6
PFLQPPPAAGTFGCS	FOXI3	91	A8MTJ6
VAPGAPAAPAGLQLP	MAP3K10	76	Q02779
QPGPPVAAANFPLGS	MAGEL2	696	Q9UJ55
APPEGQPAALGFTVA	LGR6	721	Q9HBX8
AHLAFPPEPAPVNAG	MYO16	1591	Q9Y6X6
PPAQSLNPFLAPGAP	EPN2	531	O95208
LNPFLAPGAPATSAP	EPN2	536	O95208
PISSAPGGLAPFSFP	MCM3AP	181	O60318
PNIGPSFPVGPFLSQ	ZFPM2	486	Q8WW38
ASPGRLFPGAPPTAA	JUND	26	P17535
TALQNPDGAAPPAPG	CDH24	701	Q86UP0
LPQRPGPFPGASAPF	PDCD7	41	Q8N8D1
GPFPGASAPFLQPPL	PDCD7	46	Q8N8D1
APVPAQVPAPAPGFA	PLSCR3	36	Q9NRY6
QVPAPAPGFALFPSP	PLSCR3	41	Q9NRY6
APGFALFPSPGPVAL	PLSCR3	46	Q9NRY6
LFPSPGPVALGSAAP	PLSCR3	51	Q9NRY6
NGPGTAVPAPTDFRP	PLXNB1	766	O43157
LGAFPPAAAARGPPK	FGFRL1	16	Q8N441
PPVAPPAAVAAVAGG	IGFBP2	56	P18065
APVVPSSFNFGGPAP	IPO7	1021	O95373
GPAAASSPARPPGLQ	FAM110A	171	Q9BQ89
AGPPATLPFPLAPAA	HMX1	296	Q9NP08
FNFDSALPPPPPGLA	FOXO6	466	A8MYZ6
APGVLFAPSAPAPNL	NRXN2	1546	Q9P2S2
VFAGFAPHPAALGPP	MEX3D	146	Q86XN8
AAPLPQTGAGEAPPA	LMTK2	26	Q8IWU2
QAAPGVGPPFSQAPA	MED25	311	Q71SY5
FPAGGPPPAAAAAAT	HAND1	56	O96004
FVGGAPPEFQPSPLR	LAMA2	2661	P24043
APVPPGAAPANGRLS	FAM83A	306	Q86UY5
PPGDPSAAFQGKDPA	KMT2B	1556	Q9UMN6
VPVGAAASFSAPPIP	DNM2	796	P50570
GQPPGAAKPALTPSF	POM121B	561	A6NF01
FGNSAAPAAAPTPAP	POM121B	581	A6NF01
QFGRAPVPPFAQPFG	PALLD	771	Q8WX93
GFPADEANSSPPLPG	PXN	161	P49023
PAFPILGTTPAFGPQ	PALB2	726	Q86YC2
VPLALAGAPVAGFPP	PAN3	86	Q58A45
ASAFGAGPTQPPHPV	IRS2	851	Q9Y4H2
AFGVAATPPQPIAAP	IRS2	1076	Q9Y4H2
PSPAGPVGINPAPFT	DERPC	451	P0CG12
PFPRVGSLPGTNPAA	DERPC	491	P0CG12
GLAAAAAAGPFPAPL	KCNA7	176	Q96RP8
TNFPIPGEPGFPLNA	ARPC3	101	O15145
PVAFNPFLIPGVSPG	CHD6	2606	Q8TD26
ARGPAPAPGDFAPVF	DHH	276	O43323
NPAGSRLSFPPVPGQ	C7orf57	191	Q8NEG2
GPPAAVQLFRGPTPS	FBXL17	171	Q9UF56
PAPGAGLPVPALFDS	FANCA	806	O15360
PAGAAGPAPRLSLQP	CACNA1I	926	Q9P0X4
GFGFDVPPQPPFQAA	HOXB3	26	P14651
PPAPAGGLPAAQSRL	C2CD4D	111	B7Z1M9
SPAPPGVIPFQSGFI	COL27A1	61	Q8IZC6
PPAQHAAFLVPLGPG	LTBP3	201	Q9NS15
GFQAQGHPPSLFPPK	ATE1	231	O95260
PNGTRLSPIAPAPGF	KLF10	336	Q13118
AAPAPQPVFVGPAVP	KLF11	321	O14901
LPGPNASPFLPQAYG	FOXI1	76	Q12951
QARAVGYPGAPPPAA	GJA3	281	Q9Y6H8
FPSGGAAVPQAAAPP	FAM8A1	151	Q9UBU6
LPTPGLPQFPSAAAA	OTP	176	Q5XKR4
NDSLGGLSPAPPPFL	SYNPO2L	496	Q9H987
AAAGPALLPSPGPAA	TAF3	821	Q5VWG9
ALAPRGPNASPTVGP	REXO1	126	Q8N1G1
PGPAAALPPGSAARA	UVRAG	16	Q9P2Y5
AAAAPSPVLGNIPPG	SSBP2	96	P81877
ALAGLGFPAPAEPQP	THBD	11	P07204
AGPPGLPATQDPAAL	PLEKHH3	316	Q7Z736
APPLPGAESFPGSQV	PLEKHN1	321	Q494U1
TPATPGGLPPAAAVA	PUF60	311	Q9UHX1
APAAAPPGAIPLNGF	TMEM200C	236	A6NKL6
VAPGAGPAAQAPALA	TDRD9	46	Q8NDG6
AAAPGSPFAPFLGPS	NKX1-2	286	Q9UD57
ALPSPPASFPGQAPF	PRR36	1021	Q9H6K5
ELPALGNPAAAAPPG	ARHGAP27	66	Q6ZUM4
APPPPAPVNGSVFIA	RNF167	71	Q9H6Y7
FGSLAPAPLVFPGPS	RNF167	321	Q9H6Y7
GAFGDAPATEQPPLP	SIN3B	746	O75182
FPAPLSLDAGPGVVP	SBNO2	1276	Q9Y2G9
SPGQRPPVPAAAAAG	SOWAHB	166	A6NEL2
DVQALGFLSGSPPPP	STRC	301	Q7RTU9
SFKPVQAPGSGAPAP	SUPT20HL2	591	P0C7V6
PGPRAFQLPDAGAAP	B3GNT9	51	Q6UX72
PLQTPAAPGAAAGPA	BCL2	71	P10415
AAPGAAAGPALSPVP	BCL2	76	P10415
PGFPQAVPPTGAFAS	AGFG2	401	O95081
AVPPTGAFASSFPAP	AGFG2	406	O95081
SSFQPFPAVPPPAAG	CITED4	71	Q96RK1
GPSGPAFVQPLLSAG	CIC	1046	Q96RK0
LTAGPSVAVPPQAPF	CLTC	1641	Q00610
PANSSDAPFIRPGPG	CHST8	126	Q9H2A9
LPQARPLPSPGAAGA	TNRC18	1351	O15417
GAGPAPTQLAALPAP	VWA1	316	Q6PCB0
NGPALADGPAPVSPL	TTBK1	1016	Q5TCY1
PPLGNLAPFNSGPAA	ZFHX2	2236	Q9C0A1
APAPKAPATPGAQLA	SEMA4G	656	Q9NTN9
GAPPPFDAQILPGAQ	NUFIP1	76	Q9UHK0
PVLQGPAPAGFSQHP	SEC16A	76	O15027
FAPGPLPTPFKTNGQ	SLITRK1	281	Q96PX8
AAVFARVASPPPGAP	SPEG	2276	Q15772
PAPGLAQPAAPAQAS	SARG	386	Q9BW04
AGKALAQAPAPAPGP	SARG	406	Q9BW04
AASSLAPGPPPFGLE	TAPBP	191	O15533
ANGSLEPPAQAAPGP	STK10	466	O94804
PAPGPTAPPAFASLF	SUFU	16	Q9UMX1
PAQPADRGSPAAPGQ	AXL	876	P30530
APGPEAGPPLNLFTS	PRSS42P	51	Q7Z5A4
ALRFQSLPPPAGPGT	SEZ6	331	Q53EL9
RLGPAQPGADSSFPP	TBX6	16	O95947
APPAVPFAPHFLQGG	TBX6	401	O95947
PPANPHPQFGGALSL	TBXT	256	O15178
GAAQRPGPAAASVPP	USF2	121	Q15853
GPAAPFPLAVIQNPF	USF2	136	Q15853
PPGPGTVALAQPAAS	ZBTB47	116	Q9UFB7
AALGPGAAPFAPLQP	ZMIZ2	721	Q8NF64
GAAPFAPLQPPSVPA	ZMIZ2	726	Q8NF64
NSFPGANFGVPPAEP	ZNF469	241	Q96JG9
FPPAPPAPGAAQIRA	TPRN	106	Q4KMQ1
GPGVAAPALPPAAAL	ZZEF1	36	O43149
DVQALGFLSGSPPPP	STRCP1	301	A6NGW2
HLFPPPTPIFAGGAN	WSB1	296	Q9Y6I7
PAPAALVAQPGAPGA	WNK2	96	Q9Y3S1
TAAPGLPVGSVPAPA	WNK2	676	Q9Y3S1
LVAPAGAPAAPPTNA	ZC3H10	331	Q96K80
PPSFSKPNIEGAPGA	SEC31A	1076	O94979
PVPFPSDALVGAGIP	TLE2	431	Q04725
NGPIFPPTNLAGPVA	ZFPL1	101	O95159
PPATPDAALAGNGPV	TBC1D2	151	Q9BYX2
PGPQRPDQSAAAAGP	TRIR	86	Q9BQ61
SVPAPGGPAAQAAPA	TTF2	321	Q9UNY4
PPAPPAQASFGAFSG	UNCX	416	A6NJT0
AGEKPGPAAPAPAAQ	ZNF628	21	Q5EBL2
VFPAGLLQPPFFHPG	KEL	551	P23276
GALGSPPPAAAPTIF	KMT2D	2111	O14686
SGFQALDVPPPAGPF	NAPSA	356	O96009