Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type peptidase activity

MASP1 RELN PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN MMP2

6.72e-062071269GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

MASP1 RELN PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN MMP2

8.14e-062121269GO:0017171
GeneOntologyMolecularFunctionserine-type endopeptidase activity

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN MMP2

2.80e-051901268GO:0004252
GeneOntologyMolecularFunctionextracellular matrix structural constituent

RELN SSPOP THBS3 FBN2 HMCN1 IGFBP6 TNXB

1.93e-041881267GO:0005201
GeneOntologyMolecularFunctionendopeptidase activity

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 ADAMTS13 TYSND1 CORIN ADAM33 MMP2

4.04e-0443012610GO:0004175
GeneOntologyCellularComponentextracellular matrix

RELN CD248 ADAMTS13 SSPOP ITGB4 LGALS3BP THBS3 FBN2 PHOSPHO1 HMCN1 IGFBP6 OTOGL SEMA3B FGFR2 FLRT1 MMP2 ANGPTL7 TNXB HCFC1

1.67e-0865612719GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

RELN CD248 ADAMTS13 SSPOP ITGB4 LGALS3BP THBS3 FBN2 PHOSPHO1 HMCN1 IGFBP6 OTOGL SEMA3B FGFR2 FLRT1 MMP2 ANGPTL7 TNXB HCFC1

1.75e-0865812719GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

RELN SSPOP ITGB4 LGALS3BP THBS3 FBN2 HMCN1 IGFBP6 SEMA3B FGFR2 MMP2 ANGPTL7 TNXB HCFC1

4.30e-0653012714GO:0062023
GeneOntologyCellularComponentaxon

DPYSL2 RELN MYCBP2 PRSS12 CNTNAP1 DYRK1A BLOC1S5 KCNJ11 TRPV4 C4A PAWR MAPK1 PUM1 HCFC1 PINK1

3.37e-0489112715GO:0030424
DomainEGF_1

MASP1 RELN CD248 CNTNAP1 SSPOP ITGB4 THBS3 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD ADAM33 TNXB NOTCH4

1.51e-1125512516PS00022
DomainEGF_2

MASP1 RELN CD248 CNTNAP1 SSPOP ITGB4 THBS3 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD ADAM33 TNXB NOTCH4

2.69e-1126512516PS01186
DomainEGF_3

MASP1 RELN CD248 CNTNAP1 SSPOP THBS3 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD ADAM33 TNXB NOTCH4

5.33e-1123512515PS50026
DomainEGF-like_CS

MASP1 RELN CD248 CNTNAP1 ITGB4 THBS3 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD ADAM33 TNXB NOTCH4

2.33e-1026112515IPR013032
DomainEGF-like_dom

MASP1 RELN CD248 CNTNAP1 THBS3 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD ADAM33 TNXB NOTCH4

1.28e-0924912514IPR000742
DomainEGF_CA

MASP1 CD248 THBS3 FAT1 FBN2 HMCN1 UMODL1 UMOD NOTCH4

6.00e-09861259PF07645
DomainEGF

RELN CD248 CNTNAP1 THBS3 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD ADAM33 TNXB NOTCH4

6.27e-0923512513SM00181
DomainEGF_Ca-bd_CS

MASP1 CD248 THBS3 FAT1 FBN2 HMCN1 UMODL1 UMOD NOTCH4

1.75e-08971259IPR018097
DomainEGF_CA

MASP1 CD248 THBS3 FAT1 FBN2 HMCN1 UMODL1 UMOD NOTCH4

2.10e-08991259PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

MASP1 CD248 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD NOTCH4

3.83e-081061259IPR000152
DomainGrowth_fac_rcpt_

CD248 THBS3 FAT1 FBN2 HMCN1 IGFBP6 UMODL1 UMOD TNXB NOTCH4

9.64e-0815612510IPR009030
DomainEGF_CA

MASP1 CD248 THBS3 FAT1 FBN2 HMCN1 UMODL1 UMOD NOTCH4

1.30e-071221259SM00179
DomainEGF-like_Ca-bd_dom

MASP1 CD248 THBS3 FAT1 FBN2 HMCN1 UMODL1 UMOD NOTCH4

1.50e-071241259IPR001881
DomainASX_HYDROXYL

MASP1 FAT1 NRXN3 FBN2 HMCN1 UMODL1 UMOD NOTCH4

3.57e-071001258PS00010
DomainEGF

CD248 CNTNAP1 FAT1 NRXN3 HMCN1 UMOD TNXB NOTCH4

2.09e-061261258PF00008
DomainTryp_SPc

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN

1.37e-051171257SM00020
DomainTrypsin_dom

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN

1.71e-051211257IPR001254
DomainTrypsin

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN

1.71e-051211257PF00089
DomainPeptidase_S1_PA

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 TYSND1 CORIN

1.90e-051231257IPR009003
DomainSR

PRSS12 TMPRSS4 LGALS3BP CORIN

2.17e-05251254SM00202
DomainSRCR-like_dom

PRSS12 TMPRSS4 LGALS3BP CORIN

2.55e-05261254IPR017448
DomainSRCR_1

PRSS12 TMPRSS4 LGALS3BP CORIN

2.55e-05261254PS00420
DomainSRCR_2

PRSS12 TMPRSS4 LGALS3BP CORIN

2.55e-05261254PS50287
DomainSRCR

PRSS12 TMPRSS4 LGALS3BP CORIN

2.98e-05271254IPR001190
DomainTRYPSIN_SER

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 CORIN

3.13e-05901256IPR033116
DomainTRYPSIN_HIS

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 CORIN

6.70e-051031256IPR018114
DomainTRYPSIN_SER

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 CORIN

7.87e-051061256PS00135
DomainTRYPSIN_HIS

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 CORIN

8.29e-051071256PS00134
DomainPeptidase_S1A

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 CORIN

1.12e-041131256IPR001314
DomainTRYPSIN_DOM

MASP1 PRSS12 KLK12 TMPRSS4 PRSS33 CORIN

1.24e-041151256PS50240
Domain-

PRSS12 TMPRSS4 LGALS3BP

6.04e-042512533.10.250.10
DomainLaminin_G

CNTNAP1 THBS3 FAT1 NRXN3

6.14e-04581254IPR001791
DomainEGF_extracell

RELN ITGB4 ADAM33 TNXB

6.98e-04601254IPR013111
DomainEGF_2

RELN ITGB4 ADAM33 TNXB

6.98e-04601254PF07974
DomainFibrinogen_C

CNTNAP1 ANGPTL7 TNXB

7.61e-04271253PF00147
DomainTSP_1

THSD7A ADAMTS13 SSPOP HMCN1

8.40e-04631254PF00090
DomainIg-like_fold

SIGLEC12 LILRB3 MYCBP2 LILRA6 VSIG10 ITGB4 HMCN1 UMODL1 SEMA3B FGFR2 FLRT1 TNXB HCFC1

9.03e-0470612513IPR013783
DomainSRCR_2

TMPRSS4 CORIN

9.13e-0471252PF15494
DomainFBG

CNTNAP1 ANGPTL7 TNXB

9.42e-04291253SM00186
DomainTSP1

THSD7A ADAMTS13 SSPOP HMCN1

9.44e-04651254SM00209
DomainTSP1_rpt

THSD7A ADAMTS13 SSPOP HMCN1

9.44e-04651254IPR000884
DomainTSP1

THSD7A ADAMTS13 SSPOP HMCN1

9.44e-04651254PS50092
Domain-

CNTNAP1 ANGPTL7 TNXB

1.04e-033012533.90.215.10
DomainFibrinogen_a/b/g_C_1

CNTNAP1 ANGPTL7 TNXB

1.04e-03301253IPR014716
DomainN6_MTASE

ZCCHC4 MGAM2

1.21e-0381252PS00092
DomainFIBRINOGEN_C_1

CNTNAP1 ANGPTL7 TNXB

1.26e-03321253PS00514
DomainFibrinogen_a/b/g_C_dom

CNTNAP1 ANGPTL7 TNXB

1.26e-03321253IPR002181
DomainFIBRINOGEN_C_2

CNTNAP1 ANGPTL7 TNXB

1.26e-03321253PS51406
Domainig

SIGLEC12 LILRB3 LILRA6 VSIG10 HMCN1 SEMA3B

1.77e-031901256PF00047
DomainImmunoglobulin

SIGLEC12 LILRB3 LILRA6 VSIG10 HMCN1 SEMA3B

1.77e-031901256IPR013151
DomainUBA

VPS13D LATS2 UBQLN3

1.78e-03361253PF00627
DomainLAM_G_DOMAIN

CNTNAP1 FAT1 NRXN3

2.08e-03381253PS50025
DomainGFP-like

HMCN1 UMOD

2.35e-03111252IPR023413
Domain-

HMCN1 UMOD

2.35e-031112522.40.155.10
DomainLaminin_G_2

CNTNAP1 FAT1 NRXN3

2.41e-03401253PF02210
DomainPept_M10_metallopeptidase

ADAMTS13 ADAM33 MMP2

2.97e-03431253IPR001818
DomainUBA

VPS13D LATS2 UBQLN3

3.17e-03441253IPR015940
DomainLamG

CNTNAP1 FAT1 NRXN3

3.17e-03441253SM00282
DomainLdl_recept_a

TMPRSS4 SSPOP CORIN

3.38e-03451253PF00057
Domain-

TMPRSS4 SSPOP CORIN

3.60e-034612534.10.400.10
Domain-

CNTNAP1 THBS3 FAT1 NRXN3

3.81e-039512542.60.120.200
DomainUBA

VPS13D LATS2 UBQLN3

3.83e-03471253PS50030
DomainZP_2

UMODL1 UMOD

3.84e-03141252PS51034
DomainZP_1

UMODL1 UMOD

3.84e-03141252PS00682
DomainNeurexin-like

CNTNAP1 NRXN3

3.84e-03141252IPR003585
Domain4.1m

CNTNAP1 NRXN3

3.84e-03141252SM00294
DomainLDLRA_1

TMPRSS4 SSPOP CORIN

4.06e-03481253PS01209
DomainLDrepeatLR_classA_rpt

TMPRSS4 SSPOP CORIN

4.31e-03491253IPR002172
DomainLDLa

TMPRSS4 SSPOP CORIN

4.31e-03491253SM00192
DomainLDLRA_2

TMPRSS4 SSPOP CORIN

4.31e-03491253PS50068
DomainAnk

LRRK1 CLPB NFKBIE TRPV4 GPANK1 NOTCH4

4.36e-032281256PF00023
DomainZP

UMODL1 UMOD

4.41e-03151252SM00241
Domain-

SIGLEC12 MYCBP2 VSIG10 ITGB4 HMCN1 UMODL1 SEMA3B FGFR2 FLRT1 TNXB HCFC1

4.96e-03663125112.60.40.10
DomainCUB

MASP1 ADAMTS13 SEZ6L2

5.37e-03531253PS01180
DomainEMI

SSPOP UMODL1

5.66e-03171252PS51041
DomainZP_dom

UMODL1 UMOD

5.66e-03171252IPR001507
DomainZona_pellucida

UMODL1 UMOD

5.66e-03171252PF00100
DomainSUSHI

MASP1 CD248 SEZ6L2

6.27e-03561253PS50923
Domain-

LRRK1 CLPB NFKBIE TRPV4 GPANK1 NOTCH4

6.51e-0324812561.25.40.20
DomainSushi_SCR_CCP_dom

MASP1 CD248 SEZ6L2

6.58e-03571253IPR000436
DomainCUB_dom

MASP1 ADAMTS13 SEZ6L2

6.58e-03571253IPR000859
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYCBP2 SHC1 DYRK1A LHPP LRRK1 BIRC6 ITGB4 DIP2A FAT1 TNRC18 SARS2 PNPLA6 LATS2 KCNJ11 HELZ2 FGFR2 NUP188 PUM1 BRAT1 ULK2 HCFC1

8.21e-1011051292135748872
Pubmed

Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

DDAH2 C4A TNXB GPANK1 NOTCH4

1.95e-0655129514656967
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

DPYSL2 MYCBP2 SUN1 CNTNAP1 SEZ6L2 ITGB4 LGALS3BP THBS3 FAT1 FBN2 GTF3C1 SEMA3B PKD2 IPO13 C4A MMP2 MTARC1

2.34e-0612011291735696571
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

MYCBP2 TYSND1 ACTR3 TKT NUP188 FLOT1 BRAT1 MTARC1

6.85e-06264129832814769
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

THSD7A ADAMTS13 SSPOP HMCN1 MMP2

9.10e-0675129520637190
Pubmed

Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer.

PKD2 TRPV4

1.37e-052129220682256
Pubmed

Tumor stroma marker endosialin (Tem1) is a binding partner of metastasis-related protein Mac-2 BP/90K.

CD248 LGALS3BP

1.37e-052129218490383
Pubmed

TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression.

TROAP DYRK1A

1.37e-052129233500384
Pubmed

Association study between the TNXB locus and schizophrenia in a Japanese population.

TNXB NOTCH4

1.37e-052129217192952
Pubmed

Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.

LILRB3 LILRA6

1.37e-052129233526815
Pubmed

Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B.

IGFBP6 SEMA3B

1.37e-052129218985860
Pubmed

Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells.

SHC1 PINK1

1.37e-052129220637729
Pubmed

TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.

PKD2 TRPV4

1.37e-052129223977387
Pubmed

Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.

LILRB3 LILRA6

1.37e-052129236449053
Pubmed

Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway.

MMP2 TNXB

1.37e-052129215212943
Pubmed

Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.

SHC1 ITGB4

1.37e-052129211044453
Pubmed

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.

LILRB3 LILRA6

1.37e-052129219617579
Pubmed

Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration.

UMODL1 UMOD

1.37e-052129223190605
Pubmed

Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.

SHC1 MAPK1

1.37e-052129223584453
Pubmed

Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.

LILRB3 LILRA6

1.37e-052129224096970
Pubmed

A Method to Identify p62's UBA Domain Interacting Proteins.

RELN TKT ULK2

1.76e-0514129314702098
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

DPYSL2 HAUS6 BIRC6 ACTR3 GTF3C1 GLDC TKT NUP188 PUM1 ALDH5A1

3.22e-055341291035032548
Pubmed

Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.

C4A TNXB NOTCH4

3.26e-0517129323028341
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DPYSL2 MYCBP2 DDX42 BIRC6 ACTR3 GTF3C1 POP1 HELZ2 NUP188 PUM1 HCFC1

3.38e-056531291122586326
Pubmed

Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach.

DDAH2 TNXB NOTCH4

3.91e-0518129319143821
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYCBP2 SUN1 SHC1 ARMCX4 BIRC6 LGALS3BP DIP2A VPS13D SARS2 CLPB MCUR1 SAMM50 NUP188 FLOT1 ALDH5A1 DDX4 MTARC1

4.01e-0514961291732877691
Pubmed

Expression of aquaporin 8 and phosphorylation of Erk1/2 in cervical epithelial carcinogenesis: correlation with clinicopathological parameters.

AQP8 MAPK1

4.09e-053129225120769
Pubmed

circPKD2 inhibits the glioma cell proliferation, invasion and glycolytic metabolism through regulating the miR-1278/LATS2 axis.

LATS2 PKD2

4.09e-053129236796622
Pubmed

LATS2 as a poor prognostic marker regulates non-small cell lung cancer invasion by modulating MMPs expression.

LATS2 MMP2

4.09e-053129227470365
Pubmed

Activation of extracellular signal-related kinase in abdominal aortic aneurysm.

MMP2 MAPK1

4.09e-053129226988568
Pubmed

Ouabain elicits human glioblastoma cells apoptosis by generating reactive oxygen species in ERK-p66SHC-dependent pathway.

SHC1 MAPK1

4.09e-053129225217205
Pubmed

The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.

FGFR2 MMP2

4.09e-053129225975224
Pubmed

PINK1 alleviates palmitate induced insulin resistance in HepG2 cells by suppressing ROS mediated MAPK pathways.

MAPK1 PINK1

4.09e-053129227423393
Pubmed

RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.

FGFR2 MAPK1

4.09e-053129217694057
Pubmed

PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.

ITGB4 PKD2

4.09e-053129226580203
Pubmed

Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice.

DYRK1A MAPK1

4.09e-053129222923366
Pubmed

Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion.

PKD2 MMP2

4.09e-053129226507660
Pubmed

Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2).

SHC1 FGFR2

4.09e-053129218840094
Pubmed

Protein Interaction Network of Human Protein Kinase D2 Revealed by Chemical Cross-Linking/Mass Spectrometry.

ACTR3 PKD2

4.09e-053129227559607
Pubmed

Role of MMP2 and MMP9 in TRPV4-induced lung injury.

TRPV4 MMP2

4.09e-053129225150065
Pubmed

Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion.

MMP2 TNXB

4.09e-053129212419962
Pubmed

TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel.

PKD2 TRPV4

4.09e-053129225114176
Pubmed

Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.

C4A TNXB

4.09e-053129218058064
Pubmed

Expression of the IIIc variant of FGF receptor-1 confers mitogenic responsiveness to heparin and FGF-5 in TAKA-1 pancreatic ductal cells.

FGFR2 MAPK1

4.09e-053129211876253
Pubmed

Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB.

FOSB MMP2

4.09e-053129216699069
Pubmed

Association between metalloproteinases 2 and 9 activity and ERK1/2 phosphorylation status in head and neck cancers: an ex vivo study.

MMP2 MAPK1

4.09e-053129220811691
Pubmed

Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK.

TRPV4 MAPK1

4.09e-053129226043006
Pubmed

Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs.

PKD2 TRPV4

4.09e-053129215858826
Pubmed

Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct.

PKD2 TRPV4

4.09e-053129231313950
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

ABCA3 FBN2 FGFR2 MMP2

4.26e-0552129430389913
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

RELN SSPOP FBN2 HMCN1 TNXB HCFC1

5.08e-05175129628071719
Pubmed

Global landscape of HIV-human protein complexes.

CHAF1A SUN1 CNTNAP1 LARS1 TYSND1 LGALS3BP FBN2 FLOT1 SLC27A4

5.51e-05457129922190034
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

SIGLEC12 KLK12 TMPRSS4 SEZ6L2 ADAM33 SLC49A3 FLRT1 SHISAL2A ANGPTL7

5.79e-05460129920562862
Pubmed

ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.

MASP1 KRT16 SHC1 FBN2 HCFC1

6.62e-05113129534474245
Pubmed

Recombination in the class III region of the mouse major histocompatibility complex.

C4A TNXB NOTCH4

7.29e-052212937916002
Pubmed

ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.

PKD2 MAPK1

8.15e-054129219766642
Pubmed

Non-redundant role of Shc in Erk activation by cytoskeletal reorganization.

SHC1 MAPK1

8.15e-054129214576154
Pubmed

Primary Cilia Deficiency Induces Intracranial Aneurysm.

PKD2 MMP2

8.15e-054129228800037
Pubmed

Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival.

MYCBP2 PAWR

8.15e-054129224992930
Pubmed

Human chorionic gonadotropin β induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells.

MMP2 MAPK1

8.15e-054129223424616
Pubmed

Ligation of beta4 integrins activates PKB/Akt and ERK1/2 by distinct pathways-relevance of the keratin filament.

ITGB4 MAPK1

8.15e-054129220307589
Pubmed

[Baicalein induces HeLa cell growth inhibition by down-regulation of matrix metalloproteinases and activating extracellular signal-regulated kinase].

MMP2 MAPK1

8.15e-054129225108429
Pubmed

Prenatal exposure to cocaine decreases adenylyl cyclase activity in embryonic mouse striatum.

FOSB MAPK1

8.15e-054129214741752
Pubmed

ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression.

KRT16 MAPK1

8.15e-054129217623675
Pubmed

The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling.

FGFR2 MAPK1

8.15e-054129220503384
Pubmed

Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes.

SHC1 ITGB4

8.15e-05412927556090
Pubmed

NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis.

FOSB NOTCH4

8.15e-054129237478314
Pubmed

A sperm component, HSD-3.8 (SPAG1), interacts with G-protein beta 1 subunit and activates extracellular signal-regulated kinases (ERK).

SPAG1 MAPK1

8.15e-054129216368546
Pubmed

A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers.

FOSB MMP2

8.15e-054129212371906
Pubmed

AKT and MAPK signaling in KGF-treated and UVB-exposed human epidermal cells.

FGFR2 MAPK1

8.15e-054129217458890
Pubmed

Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling.

FGFR2 MAPK1

8.15e-054129219117954
Pubmed

Spatial and temporal patterns of ERK signaling during mouse embryogenesis.

FGFR2 MAPK1

8.15e-054129212925581
Pubmed

Growth hormone (GH) induces the formation of protein complexes involving Stat5, Erk2, Shc and serine phosphorylated proteins.

SHC1 MAPK1

8.15e-054129210996427
Pubmed

FGFR2c-mediated ERK-MAPK activity regulates coronal suture development.

FGFR2 MAPK1

8.15e-054129227034231
Pubmed

A kinase shRNA screen links LATS2 and the pRB tumor suppressor.

DYRK1A LATS2

8.15e-054129221498571
Pubmed

OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts.

PKD2 FLOT1

8.15e-054129225180832
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

DPYSL2 KRT16 TKT PAWR FGD5 FLOT1

8.24e-05191129633762435
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

MYCBP2 DYRK1A ACTR3 VPS13D SARS2 PNPLA6 SAMM50 PUM1 BRAT1 MTARC1

9.21e-056061291036538041
Pubmed

Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.

DYRK1A ITGB4 MAPK1 DDX4

1.03e-0465129418729074
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

HAUS6 TROAP DDX42 TSEN2 ACTR3 LGALS3BP GTF3C1 TKT POP1 PAWR SAMM50 NUP188 FLOT1 HCFC1

1.03e-0411551291420360068
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DPYSL2 HAUS6 TROAP NELFA CHAF1A ITGB4 GTF3C1 BRAT1 HCFC1

1.14e-04503129916964243
Pubmed

The mouse as a model for the effects of MHC genes on human disease.

DDAH2 C4A TNXB GPANK1

1.16e-0467129410871872
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

KRT16 MYCBP2 SUN1 DDX42 LARS1 ACTR3 LGALS3BP GTF3C1 PAWR NUP188 MAPK1 PUM1 FLOT1

1.17e-0410241291324711643
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

RNASEH2B MASP1 HAUS6 TRAF5 NELFA CHAF1A DYRK1A VSIG10 BIRC6 TSEN2 CLPB TKT MCUR1 NUP188 ULK2

1.25e-0413271291532694731
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

THSD7A ZNFX1 SSPOP TSEN2 VPS13D

1.28e-04130129512421765
Pubmed

Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis.

MAPK1 DDX4

1.36e-045129226985001
Pubmed

P66(ShcA) interacts with MAPKAP kinase 2 and regulates its activity.

SHC1 MAPK1

1.36e-045129215094067
Pubmed

Des-γ-carboxyl prothrombin induces matrix metalloproteinase activity in hepatocellular carcinoma cells by involving the ERK1/2 MAPK signalling pathway.

MMP2 MAPK1

1.36e-045129221349701
Pubmed

Up-regulation of matrix metalloproteinases-2 and -9 via an Erk1/2/NF-κB pathway in murine mast cells infected with Toxoplasma gondii.

MMP2 MAPK1

1.36e-045129223664424
Pubmed

Toward a structure-based comprehension of the lectin pathway of complement.

MASP1 C4A

1.36e-045129223911397
Pubmed

Human chorionic gonadotropin stimulates trophoblast invasion through extracellularly regulated kinase and AKT signaling.

MMP2 MAPK1

1.36e-045129218063683
Pubmed

Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons.

PCP2 PNPLA6

1.36e-045129216186328
Pubmed

An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.

PUM1 DDX4

1.36e-045129227170441
Pubmed

Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D.

MASP1 C4A

1.36e-045129220038603
Pubmed

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin beta1-ERK1/2 and-MMP2 signaling.

MMP2 MAPK1

1.36e-045129219930715
Pubmed

Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.

ITGB4 FGFR2 MAPK1

1.37e-0427129323466739
Pubmed

The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.

ITGB4 FGFR2 MMP2

1.70e-0429129319094228
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

FBN2 FGFR2 MMP2

1.88e-0430129332882513
Pubmed

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.

LGALS3BP PDLIM3 SEMA3B C4A SLC27A4 PINK1

2.01e-04225129623341629
Pubmed

PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways.

MMP2 MAPK1

2.03e-046129219199380
Cytoband6p21.3

DDAH2 C4A FLOT1 TNXB GPANK1 NOTCH4

7.99e-0525012966p21.3
CytobandEnsembl 112 genes in cytogenetic band chr6p21

DDAH2 NFKBIE C4A FLOT1 TNXB GPANK1 NOTCH4

5.76e-045031297chr6p21
Cytoband16p12

AQP8 GTF3C1

6.97e-0414129216p12
Cytoband4q35

FAT1 PDLIM3

8.03e-041512924q35
GeneFamilyProteases, serine

MASP1 PRSS12 TMPRSS4 PRSS33 CORIN

1.09e-0563845738
GeneFamilyUPF1 like RNA helicases

ZNFX1 HELZ2

1.14e-03118421169
GeneFamilyHAD Asp-based non-protein phosphatases

LHPP PHOSPHO1

1.14e-03118421045
GeneFamilyChaperonins

CLPB CCT6B

2.15e-0315842587
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ADVENTITIAL_FIBROBLAST

THBS3 PDLIM3 IGFBP6 BST1 ADAM33 TNXB

1.33e-06711286M45664
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN SSPOP THBS3 FBN2 HMCN1 IGFBP6 OTOGL TNXB

4.66e-061911288MM17059
CoexpressionDESCARTES_FETAL_CEREBELLUM_VASCULAR_ENDOTHELIAL_CELLS

CD248 PRSS12 SRARP SHC1 LATS2 PHOSPHO1 HELZ2 FGD5 SAMM50 TNXB SLC38A3 NOTCH4 PINK1

1.71e-0564512813M40158
CoexpressionNABA_MATRISOME

MASP1 RELN PRSS12 ADAMTS13 SSPOP THBS3 FBN2 HMCN1 IGFBP6 OTOGL SEMA3B ADAM33 MMP2 ANGPTL7 TNXB HCFC1

3.36e-05100812816MM17056
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN SSPOP THBS3 FBN2 HMCN1 IGFBP6 TNXB

5.18e-051961287M3008
CoexpressionNABA_CORE_MATRISOME

RELN SSPOP THBS3 FBN2 HMCN1 IGFBP6 OTOGL TNXB

5.63e-052701288MM17057
CoexpressionGSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN

MYCBP2 VSIG10 BIRC6 CHRNA4 LGALS3BP HELZ2 NUP188

5.70e-051991287M7332
CoexpressionGSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN

FOSB SHC1 THBS3 LATS2 CLPB PAWR FLOT1

5.88e-052001287M8199
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDAH2 CD248 ZCCHC4 NRXN3 IGFBP6 GLDC FGD5 MMP2 TNXB

3.37e-09183129907ca2786e62eca9feecf5e54a11864a960f7641a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS12 CNTNAP1 CRPPA PDLIM3 IGFBP6 ADAM33 MMP2 TNXB

5.43e-08179129802c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCelldroplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 THSD7A ARMCX4 ITGB4 SYT15 PDLIM3 FGD5 NOTCH4

7.93e-081881298405efea75233ecf70f7d19b630230798d817b7f2
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 FOSB THBS3 IGFBP6 MMP2 TNXB

8.60e-08190129847077579496c5340e99f61499427a3a36b566da3
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 FOSB THBS3 IGFBP6 MMP2 TNXB

8.95e-081911298a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 FOSB THBS3 IGFBP6 MMP2 TNXB

8.95e-08191129819c67a812b8ce97472d316acd15aeefe8736000d
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 PRSS12 THBS3 IGFBP6 MMP2 TNXB

9.70e-081931298428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 THBS3 IGFBP6 SEMA3B ADAM33 MMP2 TNXB

1.01e-0719412980e315c63407fa00643722a7d6138b1502f79b10d
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 THBS3 IGFBP6 SEMA3B ADAM33 MMP2 TNXB

1.01e-071941298c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCellwk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD248 THBS3 FBN2 PDLIM3 IGFBP6 BST1 ADAM33 MMP2

1.23e-0719912988de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRSS12 CRPPA ADAMTS13 FAT1 PDLIM3 PKD2 MMP2 TNXB

1.28e-07200129809537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 EXD3 LATS2 IGFBP6 ADAM33 ANGPTL7 TNXB MTARC1

1.28e-072001298f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRSS12 CRPPA FAT1 PDLIM3 PKD2 ADAM33 MMP2 TNXB

1.28e-07200129808bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

KRT16 TMPRSS4 ITGB4 FAT1 OTOGL SEMA3B ANGPTL7

3.85e-071571297dd08dc19d434e94a194076c462ee273c682abf55
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

KRT16 TMPRSS4 ITGB4 FAT1 OTOGL SEMA3B ANGPTL7

3.85e-07157129770fd6c46db4250c7de5c4686a9500689402737f6
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 THBS3 PDLIM3 IGFBP6 OTOGL MMP2 TNXB

1.08e-0618312972beb5414958d38a5341870d55229f3b1707e76bf
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS12 CRPPA ADAMTS13 PDLIM3 ADAM33 MMP2 TNXB

1.16e-0618512976712512100ccef456d2e2bd201d0987986c92ac9
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FBN2 IGFBP6 SEMA3B MMP2 TNXB

1.16e-06185129701bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

CD248 CHRNA4 IGFBP6 ADAM33 MMP2 ANGPTL7 TNXB

1.16e-0618512972c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

MASP1 CD248 PDLIM3 IGFBP6 ADAM33 MMP2 TNXB

1.16e-061851297fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

CD248 CHRNA4 IGFBP6 ADAM33 MMP2 ANGPTL7 TNXB

1.16e-06185129737db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS12 CRPPA ADAMTS13 PDLIM3 ADAM33 MMP2 TNXB

1.16e-0618512973b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A ITGB4 SYT15 PDLIM3 FGD5 FLRT1 NOTCH4

1.20e-0618612975d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDAH2 THSD7A ARMCX4 ITGB4 SYT15 PDLIM3 NOTCH4

1.20e-0618612979c7924875f70420720149287c500b4dfa8d24673
ToppCellfacs-Trachea-nan-24m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 THBS3 IGFBP6 MMP2 TNXB

1.25e-06187129771385068e3fd0bfa7822ae176113a49460c8636b
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDAH2 THSD7A ARMCX4 ITGB4 SYT15 PDLIM3 NOTCH4

1.25e-06187129712129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellfacs-Trachea-nan-24m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 THBS3 IGFBP6 MMP2 TNXB

1.25e-061871297b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDAH2 THSD7A ARMCX4 ITGB4 SYT15 PDLIM3 NOTCH4

1.25e-06187129783930ef55191eff9006113feaeabb3c2fa21fd05
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FOSB CHRNA4 IGFBP6 ADAM33 TNXB

1.25e-0618712977beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCellfacs-Trachea-nan-24m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 THBS3 IGFBP6 MMP2 TNXB

1.25e-061871297e891e571f6bb9433a0046215de6cabd89ed1effc
ToppCellmetastatic_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

SIGLEC12 HK3 HMCN1 UMODL1 BST1 TKT SHISAL2A

1.25e-0618712977375f70a970a5d5a58b7c33ada2dcf6dcef525c6
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 IGFBP6 MMP2 ANGPTL7 TNXB

1.25e-0618712972c145e9d11424939dd99012a8cedf5d998b966e9
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FBN2 IGFBP6 SEMA3B MMP2 TNXB

1.29e-061881297e54e09d34e263d5709c337914809e61e74e20591
ToppCelldroplet-Fat-Scat-21m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FBN2 IGFBP6 SEMA3B MMP2 TNXB

1.29e-0618812977fc9810ab14354cb512e2b1285562009c10203f5
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

THSD7A ITGB4 SYT15 NRXN3 PDLIM3 TRPV4 MMP2

1.29e-0618812972777eb7689b271c199021fe7d9db88ccebff14de
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 THBS3 IGFBP6 MMP2 TNXB

1.29e-0618812972cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN PRSS12 TNRC18 POP1 SEMA3B IPO13 TRPT1

1.29e-061881297c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A CD248 THBS3 IGFBP6 MMP2 ANGPTL7 TNXB

1.29e-061881297bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

DDAH2 CD248 HMCN1 IGFBP6 ADAM33 MMP2 TNXB

1.29e-061881297409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FOSB THBS3 IGFBP6 MMP2 TNXB

1.34e-061891297bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 PRSS12 THBS3 IGFBP6 MMP2 TNXB

1.34e-0618912970a8b827bba1efd885ad6c06929251c741dc3a541
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 THBS3 IGFBP6 MMP2 TNXB

1.34e-06189129756f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

RELN PRSS12 FBN2 IGFBP6 SEMA3B ADAM33 MMP2

1.39e-0619012973aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCellfacs-SCAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 THSD7A CD248 IGFBP6 ADAM33 MMP2 TNXB

1.39e-061901297dc7e92f1b18d0f5efec11d09d56ba954d4f8b3bd
ToppCellfacs-SCAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 THSD7A CD248 IGFBP6 ADAM33 MMP2 TNXB

1.39e-0619012970bb06df3d5a50416854370f234718c6cec3d773b
ToppCellfacs-SCAT-Fat-24m-Mesenchymal|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 THSD7A CD248 IGFBP6 ADAM33 MMP2 TNXB

1.39e-061901297008290bb5c79446681dd6bf354336c57ad0d6f13
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FOSB THBS3 IGFBP6 MMP2 TNXB

1.39e-061901297f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 FOSB THBS3 IGFBP6 MMP2 TNXB

1.39e-061901297c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A CD248 FAT1 IGFBP6 PKD2 MMP2 TNXB

1.44e-061911297b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 CD248 PRSS12 THBS3 IGFBP6 MMP2 TNXB

1.54e-061931297eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDAH2 CD248 THBS3 IGFBP6 PKD2 MMP2 TNXB

1.54e-06193129725248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDAH2 CD248 THBS3 IGFBP6 PKD2 MMP2 TNXB

1.54e-061931297f1f1097204e07a7bed416425b8256942038a734f
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A ARMCX4 ITGB4 SYT15 NRXN3 HMCN1 FGD5

1.54e-06193129758c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CD248 ADAMTS13 NRXN3 FGFR2 MMP2 TNXB

1.59e-061941297415801a3dfacf05f2b603fb424df3d045190a812
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CD248 ADAMTS13 NRXN3 FGFR2 MMP2 TNXB

1.59e-061941297256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 THBS3 IGFBP6 MMP2 TNXB

1.59e-0619412973d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CD248 ADAMTS13 NRXN3 FGFR2 MMP2 TNXB

1.59e-0619412977942bc83c1bdca687795b91aa232824d603f9b09
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 PDLIM3 IGFBP6 PKD2 ADAM33 MMP2 TNXB

1.65e-061951297f54bc4454270ff06e85596f98199372b50d0179f
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPYSL2 LILRB3 HK3 LILRA6 FBN2 BST1 MTARC1

1.65e-061951297580ed65b4152483b642a7e7dbdf00d03588c46f6
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 FOSB IGFBP6 MMP2 ANGPTL7 TNXB

1.71e-06196129783669ffdfe663885086571ccb0809f62aaba9752
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD248 FOSB NRXN3 PDLIM3 HMCN1 ADAM33 MMP2

1.77e-061971297378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS3 FBN2 IGFBP6 SEMA3B PKD2 MMP2 ANGPTL7

1.83e-061981297524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCellwk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD248 THBS3 PDLIM3 IGFBP6 ADAM33 MMP2 TNXB

1.89e-061991297ab0589c068c24aa989bdca083504fbad0c15221d
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

CD248 THBS3 PDLIM3 IGFBP6 ADAM33 MMP2 TNXB

1.95e-0620012979996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDLIM3 HMCN1 PKD2 ADAM33 MMP2 SH3RF3 TNXB

1.95e-062001297389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

CD248 PRSS12 FAT1 PDLIM3 PKD2 MMP2 TNXB

1.95e-062001297a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD248 PDLIM3 HMCN1 IGFBP6 ADAM33 MMP2 TNXB

1.95e-0620012976e3d1ae0ef84d3075afa40129a41169996462672
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

DPYSL2 MASP1 CD248 IGFBP6 ADAM33 MMP2 TNXB

1.95e-062001297f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellBiopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

CD248 PDLIM3 HMCN1 IGFBP6 ADAM33 MMP2 TNXB

1.95e-062001297d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCellnormal_Lung-Fibroblasts-COL14A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

CD248 PDLIM3 IGFBP6 SEMA3B ADAM33 MMP2 TNXB

1.95e-062001297ee3d06865a6300e1279edf6664320b71647f5efb
ToppCellBAL-Mild-Myeloid-TRAM-TRAM2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PCP2 PRSS33 PDZD7 TSEN2 PNPLA6 ULK2

5.24e-06151129645392bb1c6358beff33da0ca84f7696fb5824f30
ToppCellBAL-Mild-Myeloid-TRAM-TRAM2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PCP2 PRSS33 PDZD7 TSEN2 PNPLA6 ULK2

5.24e-0615112963d861285c71abe220b19a069eb9876199c6c8f39
ToppCellMild_COVID-19-Myeloid-TRAM2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

PCP2 PRSS33 PDZD7 TSEN2 PNPLA6 ULK2

5.86e-061541296ab648f6b29eb9e499e46cbdbaf3c5cf6b94d1f64
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS13 PDLIM3 ADAM33 MMP2 SLC38A3 PINK1

6.55e-0615712961e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD248 IGFBP6 ADAM33 MMP2 ANGPTL7 TNXB

1.43e-051801296c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD248 IGFBP6 ADAM33 MMP2 ANGPTL7 TNXB

1.43e-05180129632c6a3886428d82fb4355d987c6d2645f333447b
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A ARMCX4 ITGB4 SYT15 PDLIM3 CORIN

1.43e-05180129667c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MASP1 ADAMTS13 PDLIM3 HMCN1 ADAM33 TNXB

1.47e-051811296b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A ARMCX4 ITGB4 PDLIM3 FGD5 FLRT1

1.47e-0518112964ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

SIGLEC12 HK3 LGALS3BP PNPLA6 HMCN1 CORIN

1.52e-051821296a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A ITGB4 SYT15 PDLIM3 FGD5 FLRT1

1.52e-051821296c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A ITGB4 SYT15 PDLIM3 FGD5 FLRT1

1.52e-051821296d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 IGFBP6 ADAM33 MMP2 ANGPTL7 TNXB

1.52e-051821296d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

TMPRSS4 AQP8 ITGB4 HMCN1 TRPV4 FGFR2

1.57e-05183129600a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 THBS3 IGFBP6 ADAM33 MMP2 TNXB

1.57e-05183129606a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

KRT16 TMPRSS4 ITGB4 FAT1 PAWR FGFR2

1.57e-0518312960f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SSPOP FAT1 FBN2 HMCN1 OTOGL

1.62e-0518412962cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A ITGB4 SYT15 PDLIM3 FGD5 NOTCH4

1.62e-051841296087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 IGFBP6 GLDC MMP2 ANGPTL7 TNXB

1.62e-0518412964a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SSPOP FAT1 FBN2 HMCN1 OTOGL

1.62e-051841296ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SSPOP FAT1 FBN2 HMCN1 OTOGL

1.62e-0518412962b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

THSD7A ITGB4 SYT15 NRXN3 TRPV4 FGD5

1.62e-051841296b4c561924c508536fd2112e91e32176b95fdf63a
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PRSS12 IGFBP6 BST1 ADAM33 FLRT1 TNXB

1.62e-051841296607b55022de21ddb6a2d75e085df76df7abf6624
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A ITGB4 SYT15 FGD5 MMP2 NOTCH4

1.67e-051851296f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD7A LRRK1 ITGB4 HMCN1 IGFBP6 FGD5

1.72e-0518612962d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 DPYSL2 CD248 IGFBP6 MMP2 TNXB

1.72e-051861296ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD248 THBS3 IGFBP6 ADAM33 MMP2 TNXB

1.72e-0518612967c1807fca590cdccf7f5734460bac228d33964ca
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A ITGB4 SYT15 FGD5 MMP2 NOTCH4

1.77e-051871296e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A ITGB4 SYT15 FGD5 MMP2 NOTCH4

1.83e-051881296ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN ACADL CHRNA4 LGALS3BP FAT1 FLRT1

1.83e-0518812960501a8aa850bd2e347020abd1cac4d8075738189
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 3 measurement

LILRB3 LILRA6

2.68e-0461262EFO_0802705
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 6 measurement

LILRB3 LILRA6

2.68e-0461262EFO_0801767
DiseaseHead and Neck Neoplasms

FAT1 FGFR2 MAPK1

3.78e-04331263C0018671
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 CNTNAP1 DYRK1A NRXN3 MAPK1

5.03e-041521265DOID:0060041 (implicated_via_orthology)
Diseaseclinical treatment

MYCBP2 DYRK1A NOTCH4

7.20e-04411263EFO_0007056
DiseaseBone Diseases

TRPV4 MMP2

7.96e-04101262C0005940
Diseaseubiquitin-conjugating enzyme E2 G2 measurement

TNXB NOTCH4

7.96e-04101262EFO_0022035
DiseaseMalignant Head and Neck Neoplasm

FAT1 FGFR2 MAPK1

8.86e-04441263C0278996
Diseasechronic musculoskeletal pain

EXD3 SHISAL2A

1.16e-03121262EFO_0022195
Diseaseintracranial aneurysm (is_implicated_in)

PKD2 MMP2

1.16e-03121262DOID:10941 (is_implicated_in)
Diseasefocal segmental glomerulosclerosis (biomarker_via_orthology)

ACTR3 MMP2

1.16e-03121262DOID:1312 (biomarker_via_orthology)
Diseaseocular hypertension, response to triamcinolone acetonide

CRPPA ITGB4 OTOGL

1.21e-03491263EFO_0006954, EFO_1001069
Diseaseidiopathic osteonecrosis of the femoral head

CRPPA TSEN2 UMODL1

1.44e-03521263EFO_1001930
DiseaseMetabolic Bone Disorder

PHOSPHO1 MMP2

1.59e-03141262C0005944
Diseasephoneme awareness

DYRK1A ZNFX1

1.59e-03141262EFO_0021812
DiseaseOsteopenia

PHOSPHO1 MMP2

1.83e-03151262C0029453
Diseasecortical surface area measurement

DDAH2 DPYSL2 RELN MYCBP2 PRSS12 CHAF1A CRPPA FBN2 KCNJ11 PAWR FGFR2 SH3RF3 TNXB GPANK1

1.84e-03134512614EFO_0010736
DiseaseEndometrial Neoplasms

SEMA3B PAWR FGFR2

1.98e-03581263C0014170
Diseaseendoplasmic reticulum resident protein 29 measurement

TNXB NOTCH4

2.09e-03161262EFO_0020346
DiseasePre-Eclampsia

DDAH2 CORIN

2.09e-03161262C0032914
DiseaseMalignant neoplasm of breast

ABCA3 HK3 SRARP AQP8 THBS3 OTOGL POP1 ADAM33 FGD5 FGFR2 MMP2 NOTCH4

2.21e-03107412612C0006142
DiseaseAstrocytosis

ITGB4 MAPK1

2.36e-03171262C3887640
DiseaseGliosis

ITGB4 MAPK1

2.36e-03171262C0017639
Diseasefat body mass

ABCA3 MYCBP2 TMPRSS4 CRPPA CCT6B

2.44e-032171265EFO_0005409
DiseaseSeizures

CHRNA4 CLPB GLDC KCNJ11 PUM1

2.49e-032181265C0036572
DiseaseX-11470 measurement

TNXB NOTCH4

2.95e-03191262EFO_0021241
Diseasesquamous cell carcinoma (is_marker_for)

FGFR2 MMP2

2.95e-03191262DOID:1749 (is_marker_for)
Diseaseascending aortic diameter

MASP1 FBN2 HMCN1 FGD5

3.11e-031401264EFO_0021787
Diseasesaturated fatty acids to total fatty acids percentage

MTARC1 NOTCH4

3.60e-03211262EFO_0022305
DiseaseEndometrial Carcinoma

SEMA3B PAWR FGFR2

3.66e-03721263C0476089
Diseaseobesity

FAT1 NRXN3 FBN2 CLPB SLC38A3

3.82e-032411265EFO_0001073
Diseasetriacylglycerol 58:9 measurement

CCT6B TNXB

3.95e-03221262EFO_0010443
DiseaseDown syndrome (is_marker_for)

RELN DYRK1A

3.95e-03221262DOID:14250 (is_marker_for)
Diseasemethylcobalamin deficiency type cblE

SEZ6L2 NRXN3 PINK1

3.95e-03741263MONDO_0009354
Diseasebehavioural disinhibition measurement

MASP1 CRPPA MMP2

4.10e-03751263EFO_0006946
Diseaseupper aerodigestive tract neoplasm

BIRC6 CHRNA4 FLOT1 TNXB SLC38A3

4.17e-032461265EFO_0004284

Protein segments in the cluster

PeptideGeneStartEntry
RAGRACEGDLVSPMG

UMODL1

546

Q5DID0
MSSPGEAVEGGVRCR

CHRNA4

471

P43681
VMHEIGGPNVESCGE

BST1

226

Q10588
VLALSMRGGAEGQPC

BRAT1

171

Q6PJG6
VQGELSESNCGAMPR

CNTNAP1

1241

P78357
GTEEICNGGMRPVVR

BIRC6

1231

Q9NR09
MSGGGTETPVGCEAA

BLOC1S5

1

Q8TDH9
PDECMQRTGGLFGSR

DDX4

171

Q9NQI0
CIGAIAMTEPGAGSD

ACADL

166

P28330
DGISCSPAGAMGAQA

CD248

346

Q9HCU0
PGVGRFVASMAASGC

ABCA3

1301

Q99758
FQGATVGLAPVEGMC

ADAM33

306

Q9BZ11
VDILAGGPVSGGCMN

AQP8

196

O94778
QGADREESPMTGVCV

DYRK1A

741

Q13627
ECGAPGARGAATAMD

CHAF1A

6

Q13111
RGNPNGMSREVAGVD

ARMCX4

261

Q5H9R4
GTIDMRGPGQADCAV

ADAMTS13

1201

Q76LX8
AMSTVGGNSEGAPCV

MMP2

336

P08253
PGGVNCAVGSAMLTR

PAWR

86

Q96IZ0
DRMEGQRCSLQAGPG

PCP2

36

Q8IVA1
AVAAVLPAGGCGERM

CRPPA

46

A4D126
PELEVFCDMETSGGG

ANGPTL7

156

O43827
SPQVGNGFRGCMDSI

FAT1

3966

Q14517
PLGEGCFGQVVMAEA

FGFR2

486

P21802
SVGAGEPRMAPVCES

HCFC1

1246

P51610
EPRMAPVCESLQGGS

HCFC1

1251

P51610
AAGAGPEMVRGQVFD

MAPK1

6

P28482
SRCVSMPGDISGLQG

PNPLA6

416

Q8IY17
GEGSGPVMLDEVRCT

PRSS12

336

P56730
LMGRLVGTEQSGQPC

KIAA0100

1041

Q14667
MDCGSVGGQRTQRLP

MCUR1

1

Q96AQ8
LGCGALMAAGDGVRQ

MPV17L2

31

Q567V2
METQFRRGGLGCSPA

MAGEA11

1

P43364
GVPVSEAECTAMGLR

MTARC1

71

Q5VT66
QGSGPIMLDEVQCTG

LGALS3BP

81

Q08380
GFMAGSRENPCQEQG

NELFA

461

Q9H3P2
PLMCAARAGQGAAVS

GPANK1

146

O95872
MNEPSNFVDGSVRGC

MGAM2

1376

Q2M2H8
TSNMVCAGGVPGQDA

KLK12

181

Q9UKR0
LCAGMEQSLRAGPNE

LATS2

536

Q9NRM7
AVCPERAMETLNGAG

LRRK1

21

Q38SD2
GMECRGSPLVVISQG

DPYSL2

436

Q16555
AGAQVDARMLNGCTP

NFKBIE

426

O00221
CQGVPVALSGRDMIG

DDX42

281

Q86XP3
IGFGGRMVTEECPLA

KCNJ11

131

Q14654
GPNEAMVVSGFCRSP

FLOT1

6

O75955
DRGGNGCLMAPEVST

PINK1

406

Q9BXM7
RMDICLGQEEPGSRG

PDZD7

346

Q9H5P4
GLRAEENPMVGALCG

FGD5

381

Q6ZNL6
SRGVQMDAEGPCGER

NRXN3

191

Q9Y4C0
TGGDVNVEMDAAPGV

KRT16

266

P08779
SPVVASGGNMTLRCG

LILRA6

131

Q6PI73
SPVVASGGNMTLRCG

LILRB3

131

O75022
IVGDVGGAQRCGMRA

LHPP

216

Q9H008
AACGQPRMSSRIVGG

PRSS33

26

Q8NF86
LRNVAGVPGDSGRMC

HK3

696

P52790
VTCEMAQGGGPATAF

ITGB4

1676

P16144
PDGVMLCGSHDGREV

RELN

2726

P78509
GGRPCEGNAVEIIMC

HMCN1

4621

Q96RW7
PGSIGVAGRSQDDAM

PUM1

66

Q14671
SQECAGLGEMPGSFV

FOSB

41

P53539
MCQGGDFTRPNGTDD

PPIAL4H

61

A0A075B767
EVMDAGCQESAGPER

POP1

771

Q99575
MAGRLPACVVDCGTG

ACTR3

1

P61158
MQTLEPSVVCVGGDG

CERKL

246

Q49MI3
GTVDSCMGDSGGPLV

CORIN

976

Q9Y5Q5
ACAGDSGGPMVTLNR

MASP1

641

P48740
PAVGNRIDVMGGSEE

HAUS6

716

Q7Z4H7
GVPSRAGLGMCALAA

CLPB

106

Q9H078
GCSGSMLETADGVPV

DIP2A

251

Q14689
EMDECFETGPQGGVA

FLRT1

346

Q9NZU1
PGLAVGMDGRVCVDT

FBN2

686

P35556
CGMGGPRTVVAGSSD

DDAH2

176

O95865
SSGPIQVRGRLDCGM

HELZ2

1151

Q9BYK8
VPMGVQTGDRICDGV

SAMM50

446

Q9Y512
MERREEQPGAAGAGA

IPO13

1

O94829
NSAGVQDTEMGPCRR

IGFBP6

151

P24592
CPVLDRSMQGGLVGN

C4A

1121

P0C0L4
GTRCQIIPNMGNGRD

OTOGL

106

Q3ZCN5
DVFIQMPASREEGGG

RNFT2

86

Q96EX2
PDLLRGAVFEGCGMT

SARS2

261

Q9NP81
GEEAVCSAGATPSMG

SYPL2

196

Q5VXT5
MEGTAGGERPSVVNG

TSEN2

161

Q8NCE0
GGLGDACMVGAINPE

SYT15

116

Q9BQS2
AIEDGCMVPGAGAIE

CCT6B

401

Q92526
GNQRVEDPARSCMEG

SLC38A3

31

Q99624
PASGAALGMVADCGV

ALDH5A1

81

P51649
TPMGGGCLAQARATL

SRARP

96

Q8NEQ6
TMERHRTCEGGPGVA

SSPOP

4786

A2VEC9
VTGGCLVMSQPDADR

THSD7A

1501

Q9UPZ6
QPCMDHDRQTGEGVG

LARS1

246

Q9P2J5
EVSPDCQGVNTGMAA

SHISAL2A

111

Q6UWV7
ANGDGGMTTVQCPDG

MYCBP2

1841

O75592
VHGGSGGAQRMPLCD

PDLIM3

281

Q53GG5
MCGGELSEPAGVVLS

SEZ6L2

526

Q6UXD5
VMCSGPEEGEEVGQA

NOTCH4

1526

Q99466
RPAVGVGDTGMEDAN

SIGLEC12

511

Q96PQ1
GDPGIISGMRSHCEI

TRPT1

161

Q86TN4
PDGEMNIASGCPRFV

TRAF5

511

O00463
VECSFPVGEGAATGM

SLC49A3

366

Q6UXD7
LQPSVLTMCNGGAGD

TNRC18

276

O15417
LTMCNGGAGDVGLPA

TNRC18

281

O15417
VGQGGARMAETCVPV

UMOD

206

P07911
HCGVSIGEDGPSQMA

TKT

416

P29401
MAAGVDCGDGVGARQ

RNASEH2B

1

Q5TBB1
GRAGMAAVASPTGNC

SLC27A4

546

Q6P1M0
GRAGSCPIESEMQGA

SH3RF3

771

Q8TEJ3
VEPGGGGSANSLRMC

SEMA3B

696

Q13214
EEPGRPAGEVSMGCL

SPAG1

766

Q07617
FPRDCGEEMQNGAGA

TNXB

4026

P22105
MCAGIPEGGVDTCQG

TMPRSS4

371

Q9NRS4
GGQCVPLNGGSSLDM

TROAP

451

Q12815
CGEVGMGPSSLNRHI

ZNF627

106

Q7L945
VMAAQPRSDGAEGQG

NUP188

791

Q5SRE5
VGDGANDFCPMGLLA

PHOSPHO1

201

Q8TCT1
NDFCPMGLLAGGDVA

PHOSPHO1

206

Q8TCT1
LGGSMARVGALSECP

THBS3

191

P49746
PGRLMAGCAAVGASL

PKD2

26

Q13563
VIGDCGGAMERGTCP

ZNFX1

1856

Q9P2E3
CDMPVGTAGRRASNE

ULK2

366

Q8IYT8
PDGQMLLTGSEDGCV

WDR38

31

Q5JTN6
SAGCRGSSGMEVVLP

ZCCHC4

16

Q9H5U6
VGPESGASCMVQIRG

VSIG10

296

Q8N0Z9
RVDQMEGGAAGPSAS

SUN1

396

O94901
MVAFSLDGPGGNCVA

GTF3C1

1556

Q12789
ERPMGSSQEEGLRCQ

TTLL10

71

Q6ZVT0
VVVPLDSMGNPRCDG

TRPV4

841

Q9HBA0
MPCLAGTGSVAGGIE

UBQLN3

546

Q9H347
RAADDGEGIVGAAMP

SHC1

86

P29353
GCMVSASRAGQPEAG

TYSND1

16

Q2T9J0
GREAVGSEGSRMFCP

VPS13D

1441

Q5THJ4
LVAESMGEECRGIPG

GLDC

496

P23378
MNAQVGICRPGDFGS

GLDC

731

P23378
DMLESCRGQRGEGPS

EXD3

61

Q8N9H8