Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycosylceramide flippase activity

ATP10B ATP10D

4.17e-053752GO:0140351
GeneOntologyBiologicalProcessmicrovillus assembly

TNIK MYO1A MINK1 MAP4K4

2.77e-0628734GO:0030033
GeneOntologyBiologicalProcessmicrovillus organization

TNIK MYO1A MINK1 MAP4K4

6.18e-0634734GO:0032528
DomainCNH

TNIK MINK1 MAP4K4

2.02e-0514733SM00036
DomainCNH

TNIK MINK1 MAP4K4

2.52e-0515733PF00780
DomainCNH

TNIK MINK1 MAP4K4

2.52e-0515733PS50219
DomainCNH_dom

TNIK MINK1 MAP4K4

2.52e-0515733IPR001180
DomainIGv

BTN3A3 PTGFRN BTN3A2 BTN3A1

2.12e-0475734SM00406
DomainPROTEIN_KINASE_ATP

TNIK STK10 MAP3K8 MINK1 SIK2 ROS1 LTK MAP4K4

4.16e-04459738PS00107
DomainProt_kinase_dom

TNIK STK10 MAP3K8 MINK1 SIK2 ROS1 LTK MAP4K4

6.31e-04489738IPR000719
DomainHydrolase_3

ATP10B ATP10D

6.64e-0410732PF08282
DomainPROTEIN_KINASE_DOM

TNIK STK10 MAP3K8 MINK1 SIK2 ROS1 LTK MAP4K4

6.65e-04493738PS50011
DomainProtein_kinase_ATP_BS

TNIK STK10 MINK1 SIK2 ROS1 LTK MAP4K4

6.91e-04379737IPR017441
DomainV-set

BTN3A3 SLAMF7 PTGFRN BTN3A2 BTN3A1

7.68e-04184735PF07686
DomainTyr_kinase_rcpt_2_CS

ROS1 LTK

8.10e-0411732IPR002011
DomainRECEPTOR_TYR_KIN_II

ROS1 LTK

9.70e-0412732PS00239
DomainIg_V-set

BTN3A3 SLAMF7 PTGFRN BTN3A2 BTN3A1

1.09e-03199735IPR013106
DomainKinase-like_dom

TNIK STK10 MAP3K8 MINK1 SIK2 ROS1 LTK MAP4K4

1.23e-03542738IPR011009
DomainP_typ_ATPase_c

ATP10B ATP10D

1.33e-0314732IPR032630
DomainP-type_ATPase_N

ATP10B ATP10D

1.33e-0314732IPR032631
DomainP-type_ATPase_IV

ATP10B ATP10D

1.33e-0314732IPR006539
DomainPhoLip_ATPase_C

ATP10B ATP10D

1.33e-0314732PF16212
DomainPhoLip_ATPase_N

ATP10B ATP10D

1.33e-0314732PF16209
DomainSer/Thr_kinase_AS

TNIK STK10 MAP3K8 MINK1 SIK2 MAP4K4

2.71e-03357736IPR008271
DomainS_TKc

TNIK STK10 MAP3K8 MINK1 SIK2 MAP4K4

2.79e-03359736SM00220
DomainPROTEIN_KINASE_ST

TNIK STK10 MAP3K8 MINK1 SIK2 MAP4K4

2.91e-03362736PS00108
DomainPkinase

TNIK STK10 MAP3K8 MINK1 SIK2 MAP4K4

3.74e-03381736PF00069
DomainIG

BTN3A3 SLAMF7 PTGFRN BTN3A2 BTN3A1 FCRL6

6.04e-03421736SM00409
DomainIg_sub

BTN3A3 SLAMF7 PTGFRN BTN3A2 BTN3A1 FCRL6

6.04e-03421736IPR003599
Domain-

ATP10B ATP10D

6.93e-03327323.40.1110.10
Domain-

ATP10B ATP10D

6.93e-03327322.70.150.10
PathwayREACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS

BTN3A3 BTN3A2 BTN3A1

1.21e-0512553M27738
PathwayWP_HIPPOYAP_SIGNALING

TNIK MINK1 MAP4K4

8.21e-0522553M39821
Pubmed

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.

BTN3A3 BTN3A2 BTN3A1

9.63e-09375322767497
Pubmed

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.

BTN3A3 BTN3A2 BTN3A1

3.85e-08475339142074
Pubmed

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

BTN3A3 BTN3A2 BTN3A1

9.60e-08575329339503
Pubmed

The cluster of BTN genes in the extended major histocompatibility complex.

BTN3A3 BTN3A2 BTN3A1

3.35e-07775311170752
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PPP1R26 STK10 SDSL TNRC18 EIF4ENIF1 TLN1 EIF2B3 LTK ARHGEF11 BIRC6 BTN3A2 CABLES1 THAP11

6.39e-071105751335748872
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TNIK STK10 AHCYL1 TRAFD1 EIF4ENIF1 JADE3 MAP3K8 EIF2B3 SIK2 XPA MAP4K4 PDLIM5

2.17e-061038751226673895
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

TNIK MINK1 MAP4K4

4.30e-061575322797597
Pubmed

Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.

BTN3A2 BTN3A1

4.59e-06275221918970
Pubmed

The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.

BTN3A2 BTN3A1

4.59e-06275222846996
Pubmed

CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.

BTN3A2 BTN3A1

4.59e-06275221113407
Pubmed

A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

BTN3A3 BTN3A2 BTN3A1

7.68e-06187539149941
Pubmed

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

TNIK MINK1

1.37e-05375218930710
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

TNIK STK10 AHCYL1 MINK1 MAP4K4 BTN3A2 CABLES1

1.75e-0537775738117590
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

TRAFD1 EIF4ENIF1 MAP4K4 BIRC6 VPS53 CABLES1

1.77e-0525175629778605
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SF3B3 TRAFD1 EIF4ENIF1 RADX EIF2B3 STYXL2 VPS53 CLUH RUSF1 MOV10 PPP4R3A THAP11

2.45e-051321751227173435
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SF3B3 EIF4ENIF1 KDM5A TLN1 MINK1 FAM83D CLUH PDLIM5 MOV10

2.58e-0572475936232890
Pubmed

Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex.

BTN3A2 BTN3A1

2.75e-0547529382921
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TNIK UBE2O EIF4ENIF1 RADX MAP4K4 BIRC6 CLUH RUSF1 PDLIM5

2.84e-0573375934672954
Pubmed

BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.

BTN3A3 BTN3A1

6.84e-05675220208008
Pubmed

NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation.

MAP3K8 MAP4K4

6.84e-05675218439422
Pubmed

Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.

ATP10B ATP10D

6.84e-05675225947375
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PPP1R26 TNRC18 ELAPOR1 BIRC6 PTGFRN MOV10 PPP4R3A

9.53e-0549375715368895
Pubmed

MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation.

TNIK HGH1 MINK1 HDDC2 MAP4K4

1.07e-0421675532640226
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

STK10 JADE3 TLN1 MINK1 SIK2 FAM83D MAP4K4 AKAP7 CABLES1

1.48e-0491075936736316
Pubmed

A secreted protein microarray platform for extracellular protein interaction discovery.

NGFR SLAMF7 BTN3A1

1.86e-045175321982860
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

TNIK SOX11 EIF4ENIF1 XPA MAP4K4

1.96e-0424675515345747
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

MAP3K8 MINK1 SIK2 MAP4K4 PDLIM5 CABLES1

2.33e-0440175625852190
Pubmed

Common variants on chromosome 6p22.1 are associated with schizophrenia.

BTN3A2 BTN3A1

2.49e-041175219571809
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

STK10 TRAFD1 JADE3 KDM5A MINK1 MAP4K4 CLUH PPP4R3A

2.63e-0477475815302935
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

AHCYL1 UBE2O HGH1 ZPR1 TLN1 EIF2B3 GBP1 BIRC6 CLUH PDLIM5 PPP4R3A

2.77e-041455751122863883
Pubmed

The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.

MINK1 MAP4K4

2.99e-041275235027733
Pubmed

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

ATP10B ATP10D

2.99e-041275221914794
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TNIK STK10 BTN3A3 MINK1 MAP4K4 CABLES1

3.02e-0442175636976175
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNIK AHCYL1 UBE2O SF3B3 TLN1 MINK1 SIK2 GATB ALAS1 MAP4K4 CLUH

3.33e-041487751133957083
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

MAP3K8 ROS1

4.11e-04147529151674
Pubmed

Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.

AJAP1 PTGFRN

4.11e-041475219850283
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

BTN3A3 ATP1B1 BTN3A2 RUSF1

5.82e-0417675428692057
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

AHCYL1 UBE2O RADX ATP1B1 MAP4K4 MOV10 THAP11

6.10e-0467075722990118
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

TNIK STK10 MAP4K4

6.52e-047875317192257
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

PPP1R26 STK10 TNRC18 UBE2O CLUH RUSF1 THAP11

7.19e-0468975736543142
Pubmed

A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.

SF3B3 KLHL13 TLN1 FAM83D

7.60e-0418975431594818
Pubmed

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

PDLIM5 BIK

7.66e-041975219767753
Pubmed

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.

PDLIM5 BIK

8.50e-042075220564319
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

TLN1 ARHGEF11 BIRC6 PDLIM5 MOV10

9.01e-0434475530333137
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

UBE2O TRAFD1 HGH1 TLN1 EIF2B3 PTGFRN VPS53 CAPN15

9.56e-0494275831073040
Pubmed

TIM-1 Ubiquitination Mediates Dengue Virus Entry.

ATP1B1 NDFIP1

1.13e-032375229742433
Pubmed

A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels.

UBE2O ATP1B1

1.23e-032475225240745
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

SF3B3 MAP3K8 KLHL13 MINK1 MAP4K4

1.27e-0337275522939624
Pubmed

HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3.

MESP1 ATP1B1

1.33e-032575227518902
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EIF4ENIF1 KDM5A TLN1 MINK1 ELAPOR1 CDC42EP5 FAM83D ATP1B1 ARHGEF11 MOV10

1.38e-031497751031527615
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PPP1R26 MAP4K4 CLUH

1.42e-031027539734811
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TNIK TLN1 SIK2 BIRC6

1.45e-0322575412168954
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TNIK STK10 AHCYL1 MINK1 MAP4K4 ATP10D

1.45e-0356975630639242
Pubmed

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.

EIF4ENIF1 TLN1 PDLIM5

1.63e-0310775330995489
Pubmed

DNA cloning using in vitro site-specific recombination.

CATSPERZ EIF2B3 TKTL1 SLAMF7 PDLIM5 MOV10 CAPN15

1.63e-0379475711076863
Pubmed

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.

ARHGEF11 RFXAP

1.67e-032875225752541
Pubmed

Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.

MAP4K4 CABLES1

1.67e-032875224462114
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

TRAFD1 HGH1 TLN1 PDLIM5

1.70e-0323575428378594
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

TNRC18 TRAFD1 KDM5A

1.76e-0311075326841866
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1B1 ATP10D

1.79e-032975215071553
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

UBE2O EIF4ENIF1 PDLIM5 MOV10

1.89e-0324275434011540
CytobandEnsembl 112 genes in cytogenetic band chr1p13

AHCYL1 ELAPOR1 PTGFRN MOV10

4.08e-04211754chr1p13
Cytoband1p13.2

AHCYL1 MOV10

2.60e-03467521p13.2
GeneFamilyButyrophilins|V-set domain containing|C2-set domain containing

BTN3A3 BTN3A2 BTN3A1

4.83e-0615413458
GeneFamilyAdenosine receptors|V-set domain containing

BTN3A3 SLAMF7 PTGFRN BTN3A2 BTN3A1

3.23e-05163415590
GeneFamilyATPase phospholipid transporting

ATP10B ATP10D

5.17e-04154121210
GeneFamilyReceptor Tyrosine Kinases|CD molecules

ROS1 LTK

3.71e-0340412321
CoexpressionGSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN

BTN3A3 TRAFD1 GBP1 ALAS1 BTN3A2 BTN3A1

2.31e-05199756M7645
CoexpressionGSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN

BTN3A3 TRAFD1 GBP1 BTN3A2 BTN3A1 ATP10D

2.31e-05199756M9595
CoexpressionGSE22886_CTRL_VS_LPS_24H_DC_DN

BTN3A3 TEX30 GBP1 SLAMF7 BTN3A2 BTN3A1

2.38e-05200756M4520
CoexpressionGSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_UP

BTN3A3 TRAFD1 GBP1 BTN3A2 BTN3A1 ATP10D

2.38e-05200756M9598
CoexpressionGSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN

BTN3A3 TRAFD1 GBP1 BTN3A2 BTN3A1 ATP10D

2.38e-05200756M9576
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

STK10 BTN3A3 KDM5A MINK1 GBP1 XPA LY96 MAP4K4 BTN3A2 BTN3A1 ATP10D MOV10 NDFIP1

6.20e-0512777513MM1032
CoexpressionLIM_MAMMARY_STEM_CELL_DN

SDSL ZSCAN20 ELAPOR1 GATB SLC49A3 ATP1B1 BIK

1.92e-04417757M2574
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN

ITPKC BICDL1 BTN3A3 BTN3A1 PDLIM5

2.12e-04189755M8275
CoexpressionGSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP

SDSL GBP1 SLAMF7 ARHGEF11 BTN3A2

2.17e-04190755M8021
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

AHCYL1 EIF4ENIF1 KDM5A MINK1 GATB GBP1 XPA LY96 MAP4K4 ATP10D NDFIP1

2.26e-0410727511MM1031
CoexpressionGSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN

STK10 BICDL1 MYO1A MAP3K8 ALAS1

2.45e-04195755M7263
CoexpressionGSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_UP

SOX11 SLC49A3 LTK ATP1B1 BTN3A1

2.51e-04196755M8157
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN

TRAFD1 GBP1 BTN3A2 BTN3A1 PPP4R3A

2.51e-04196755M6129
CoexpressionGSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP

TRAFD1 GBP1 FAM83D BTN3A2 BTN3A1

2.51e-04196755M6156
CoexpressionLIM_MAMMARY_STEM_CELL_DN

SDSL ZSCAN20 ELAPOR1 GATB SLC49A3 ATP1B1 BIK

2.52e-04436757MM1326
CoexpressionGSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN

TNRC18 GBP1 TKTL1 MAP4K4 BTN3A2

2.57e-04197755M8227
CoexpressionGSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP

BTN3A3 GBP1 BTN3A2 BTN3A1 MOV10

2.57e-04197755M7543
CoexpressionGAUTAM_EYE_CORNEA_CONJUNCTIVAL_CELLS

MAP3K8 ATP10B PDLIM5 BIK

2.65e-04108754M43607
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN

BTN3A3 GBP1 SLAMF7 BTN3A2 BTN3A1

2.69e-04199755M4635
CoexpressionGSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN

BTN3A3 TRAFD1 GBP1 BTN3A1 ATP10D

2.69e-04199755M8971
CoexpressionGSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP

BTN3A3 TRAFD1 GBP1 ALAS1 ATP1B1

2.69e-04199755M7655
CoexpressionGSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN

BTN3A3 SLC49A3 ARHGEF11 BTN3A2 BTN3A1

2.69e-04199755M6843
CoexpressionGSE11924_TH1_VS_TH17_CD4_TCELL_DN

SIK2 LY96 MAP4K4 ATP10D AKAP7

2.69e-04199755M3163
CoexpressionGSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN

STK10 ITPKC TLN1 MINK1 ATP1B1

2.75e-04200755M9472
CoexpressionGSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_DN

SOX11 STK10 SDSL EIF4ENIF1 ATP1B1

2.75e-04200755M5124
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN

BTN3A3 GBP1 HDDC2 TKTL1 SLAMF7

2.75e-04200755M4632
CoexpressionGSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP

KLHL13 GATB VPS53 PDLIM5 ATP10D

2.75e-04200755M6600
CoexpressionGSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN

TNIK ITPKC TRAFD1 GBP1 ATP10D

2.75e-04200755M9593
CoexpressionGSE1432_6H_VS_24H_IFNG_MICROGLIA_DN

BTN3A3 TKTL1 BTN3A1 AKAP7 THAP11

2.75e-04200755M3416
CoexpressionGSE1432_1H_VS_24H_IFNG_MICROGLIA_DN

BTN3A3 GBP1 BTN3A1 AKAP7 THAP11

2.75e-04200755M3414
CoexpressionGSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_DN

BICDL1 TNRC18 UBE2O KDM5A MINK1

2.75e-04200755M3960
CoexpressionGSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN

ITPKC AHCYL1 HGH1 SLAMF7 NDFIP1

2.75e-04200755M6095
CoexpressionGSE557_CIITA_KO_VS_I_AB_KO_DC_UP

MAP3K8 XPA PDLIM5 AKAP7 NDFIP1

2.75e-04200755M6012
CoexpressionDESCARTES_ORGANOGENESIS_DEFINITIVE_ERYTHROID_LINEAGE

BTN3A3 BTN3A2 BTN3A1

3.13e-0446753MM3654
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

BICDL1 NGFR AMER3 PTGFRN BIK

3.45e-04210755M2010
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6 PPP4R3A

3.99e-081957579990440bda7fac5d00ef80444fab07459be625e1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6 PPP4R3A

4.13e-08196757418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6 PPP4R3A

4.13e-08196757581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6 PPP4R3A

4.13e-081967576beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6 PPP4R3A

4.13e-08196757c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

TNIK STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

4.74e-08200757f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR1 CDC42EP5 FAM83D ATP10B MESP1 BIK

1.02e-06197756da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

1.02e-06197756836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR1 CDC42EP5 FAM83D ATP10B MESP1 BIK

1.02e-061977563fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

1.02e-06197756d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCell21-Trachea-Epithelial-Club-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

ITPKC MAP3K8 CDC42EP5 ATP10B ATP1B1 BIK

1.05e-06198756e735d82e5151c98b5724c543f8ad633c8ed824d2
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

1.08e-06199756df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

STK10 BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

1.08e-06199756ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellhealthy_donor-Lymphocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

TNIK BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

1.08e-061997562841e16d54acd344ba454f024e285c28abc37319
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR1 CDC42EP5 FAM83D MESP1 ATP1B1 BIK

1.08e-061997561e693d7bb481bf03a943b460a69787229625d7b1
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

STK10 FAM83D SLAMF7 BTN3A2 BTN3A1 FCRL6

1.08e-061997567d69785717073491b5fb81bf24db0175f86cd0b0
ToppCellsevere-Myeloid-Eosinophils|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK TEX30 ALAS1 PDLIM5 ATP10D

1.01e-05170755863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BTN3A3 SLAMF7 BTN3A2 BTN3A1 PPP4R3A

1.23e-05177755d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BTN3A3 SLAMF7 BTN3A2 BTN3A1 PPP4R3A

1.23e-05177755f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

BTN3A3 SLAMF7 BTN3A2 BTN3A1 PPP4R3A

1.23e-051777556978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

BTN3A3 SLAMF7 BTN3A2 BTN3A1 PPP4R3A

1.23e-05177755936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BTN3A3 SLAMF7 BTN3A2 BTN3A1 PPP4R3A

1.23e-05177755d5aeda113afaa2425874394610344570c9078478
ToppCellASK428-Immune-NK_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

STK10 SLAMF7 BTN3A2 BTN3A1 FCRL6

1.33e-05180755857d09446e3e6737e83d0f10bfda2ba282d5ba75
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK TEX30 ALAS1 PDLIM5 ATP10D

1.33e-05180755ac03812b1409435c55d323a7516deeac82bd3509
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

STK10 MAP3K8 TLN1 SLAMF7 FCRL6

1.44e-05183755f593a89b0aa8fffdfa403769916facfd30358521
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

1.48e-05184755c2ca984551baf4becbefbe58bd1889828542b045
ToppCellnormal-na-Lymphocytic_NK-NK_dim-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MAP3K8 TLN1 SLAMF7 BTN3A2 FCRL6

1.52e-05185755b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

1.77e-05191755cd709bbcd320373468ea7f058ee5fda8a067b5d0
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

1.77e-0519175514851529025cfc2b665f71ebad04150ec543da7a
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

1.77e-05191755e14b22e882ac92acf8c8b6ee997ef8e799c7a8d5
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

TRAFD1 GBP1 SLAMF7 ARHGEF11 MOV10

1.82e-051927551a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ELAPOR1 CDC42EP5 FAM83D ATP10B BIK

1.87e-0519375571bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR1 FAM83D ATP10B MESP1 BIK

1.87e-05193755605fc2a25ed6846fb283b2918cfed98df6039d6b
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ELAPOR1 CDC42EP5 FAM83D ATP10B BIK

1.87e-05193755b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

ITPKC CDC42EP5 FAM83D ATP10B ATP1B1

1.87e-05193755518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

ITPKC CDC42EP5 FAM83D ATP10B ATP1B1

1.87e-051937554e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCellMild_COVID-19|World / Disease group,lineage and cell class （2021.01.30）

BTN3A3 TRAFD1 MINK1 BTN3A2 BTN3A1

1.87e-05193755325b0768827bf8701bfb7f686bb11fd8b1a41a5c
ToppCellCD8+_Memory_T_cell-CV-6|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

BTN3A3 TRAFD1 TLN1 GBP1 SLAMF7

1.91e-0519475535a347c3824757b9de8b7f49db46e73e7fb63a4f
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ELAPOR1 CDC42EP5 FAM83D ATP10B BIK

1.91e-05194755d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TRAFD1 GBP1 LY96 BTN3A1 MOV10

1.91e-05194755267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K8 HDDC2 TKTL1 SLAMF7 FCRL6

1.91e-0519475552e09b14159b609af00264a8f38accf37ba8f464
ToppCellNasal_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

1.96e-051957557509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

1.96e-05195755d7e92bcbd05b93e86a1e1397e44ad27a9e2e637a
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

STK10 KDM5A SLAMF7 BTN3A2 FCRL6

1.96e-05195755003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellGoblet_1|World / shred by cell class for nasal brushing

BICDL1 CDC42EP5 ATP10B MESP1 ATP1B1

1.96e-05195755d9e4889a2e7b7c97c07c15b043b77837739462e4
ToppCellBAL-Mild|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

BTN3A3 TRAFD1 MINK1 BTN3A2 BTN3A1

2.01e-051967556566e6671257f7df4d3f375e84f0b292ab4bcde1
ToppCellBAL-Mild|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BTN3A3 TRAFD1 MINK1 BTN3A2 BTN3A1

2.01e-051967553408d561d29802fca9eff5c54ccf70818d240cea
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

2.01e-05196755af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNIK LTK SLAMF7 BTN3A1 FCRL6

2.01e-05196755093fb240e72911dfd360aa6edf8ed2d611c78a1e
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

2.01e-0519675591902e135c05d1214d915c8d8e6037929c2501b8
ToppCellMild|World / Disease group and Cell class

TRAFD1 GBP1 BTN3A2 BTN3A1 FCRL6

2.01e-051967555e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TNIK LTK SLAMF7 BTN3A1 FCRL6

2.01e-05196755c06caba0c91b8ee66f42bc43ec75eb2475f07056
ToppCell(1)_T_cells-(1)_T_CD8_CytT|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MAP3K8 SLAMF7 BTN3A2 BTN3A1 FCRL6

2.01e-051967553a4ba9ca84ce6b35038765da8c55812587b58bc2
ToppCellNS-moderate-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BICDL1 CDC42EP5 ATP10B MESP1 BIK

2.01e-0519675547930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ELAPOR1 CDC42EP5 FAM83D MESP1 SLAMF7

2.01e-05196755057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCellT_cells-CTLs|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

STK10 GBP1 SLAMF7 BTN3A1 FCRL6

2.06e-0519775528117cf300e169182571fbad0de1681a484a435a
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR1 CDC42EP5 FAM83D ATP10B BIK

2.06e-05197755a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELAPOR1 CDC42EP5 ATP10B ATP1B1 CLUH

2.06e-051977559ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELAPOR1 CDC42EP5 ATP10B ATP1B1 CLUH

2.06e-05197755c0250509836f1be04f5e54386191d7bb1e1da652
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ELAPOR1 CDC42EP5 FAM83D MESP1 SLAMF7

2.06e-051977553f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

2.06e-05197755adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

STK10 SLAMF7 BTN3A2 BTN3A1 FCRL6

2.06e-051977552de34e20915a247bee75aa40495e23c20bb23e18
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

2.11e-051987553477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellmild_COVID-19_(asymptomatic)-NK|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TNIK HDDC2 SLAMF7 BTN3A2 FCRL6

2.11e-051987551e43181c13e054570046c7a973ddc1c586e259b0
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

2.11e-05198755e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCellBiopsy_Other_PF-Epithelial-MUC5AC+_High|Biopsy_Other_PF / Sample group, Lineage and Cell type

ELAPOR1 CDC42EP5 ATP10B MESP1 BIK

2.11e-0519875530e6177e216f66caddcd009fafef0e07369f4d8e
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

2.11e-05198755da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

2.16e-0519975573704e8d774b3d08a311f69137972b07015c38f6
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

2.16e-051997558bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCell(1)_T_cell-(10)_CD8_T|(1)_T_cell / shred on Cell_type and subtype

BTN3A3 MAP3K8 SLAMF7 BTN3A1 FCRL6

2.16e-05199755d04896156e9ef6dda5f4f69fefdc7038c617d969
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

2.16e-051997550c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCellBiopsy_IPF-Epithelial-MUC5AC+_High|Biopsy_IPF / Sample group, Lineage and Cell type

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

2.16e-0519975551cb306e36537a53968c55187bd87c83e1706187
ToppCellControl-Control-Lymphocyte-T/NK-CD8+_Tem|Control / Disease, condition lineage and cell class

TNIK SLAMF7 BTN3A2 BTN3A1 FCRL6

2.21e-05200755fddb3df5b90eb97ef8ed80fac320c1a90903f012
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42EP5 ATP10B MESP1 ATP1B1 BIK

2.21e-05200755b68d212159b9d04866ba02ff55c35be247805eec
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

BTN3A3 SLAMF7 BTN3A2 BTN3A1 FCRL6

2.21e-052007552281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR1 CDC42EP5 FAM83D MESP1 BIK

2.21e-05200755133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCellsevere-NK|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MAP3K8 TLN1 HDDC2 SLAMF7 FCRL6

2.21e-05200755d6767f06fe13be8110a86c2a6029be2dd9ce666c
ToppCellileum-Absorptive_Enterocytes|ileum / shred on tissue and cell subclass

MYO1A KDM5A ATP1B1

4.53e-0541753650cec538c6acd92f45d804b3c94248c6231aa21
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PPP1R26 LTK SLAMF7 BIK

1.05e-04145754fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

EIF4ENIF1 FAM83D ATP10B ATP1B1

1.33e-04154754a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ELAPOR1 ATP10B ALAS1 ATP1B1

1.58e-04161754c4970501c038ed36de447da70eabff020ad78713
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ELAPOR1 ATP10B ALAS1 ATP1B1

1.58e-0416175441a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCell368C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KLHL13 SLAMF7 FCRL6 BIK

1.58e-041617541011094c54381d52566e24c92f89f2efc2aa3eea
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR1 CDC42EP5 FAM83D BIK

1.65e-0416375422fa5d017ff796394394d952ec151e2d1beb8248
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK10 SDSL AJAP1 RADX

1.77e-041667540a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellnormal_Pleural_Fluid-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

SOX11 CDC42EP5 FAM83D CAPN15

1.77e-04166754d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ELAPOR1 FAM83D ATP10B ATP1B1

1.81e-04167754a90f905ef38437752e2b0b71bd0322a184de1861
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TKTL1 SLAMF7 BTN3A2 FCRL6

1.85e-04168754696b31bedbc7d40817a733e8c6ec2633404be619
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BICDL1 TKTL1 FCRL6 NDFIP1

1.90e-04169754cc1b60eb50a274ffd72c67082c19e43af775e949
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MESP1 LTK SLAMF7 CABLES1

1.94e-04170754c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

BICDL1 TEX30 PNPLA1 MESP1

2.03e-04172754e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SDSL TKTL1 SLAMF7 MAP4K4

2.03e-04172754965a9f62b73a7e3531c343121a7c507b7e1bfe05
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TEX30 FAM83D TKTL1 MESP1

2.03e-04172754fe3d0d8cb5f613ac2cfff450599698f1533a354f
ToppCellASK454-Epithelial-Transformed_epithelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

ZSCAN20 EIF4ENIF1 PPP4R1L ATP1B1

2.03e-041727543986f0f098ef5e096c8d9ee3d335b8404083701f
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HDDC2 SLAMF7 BIRC6 RFXAP

2.07e-0417375428c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

ELAPOR1 GATB FCRL6 AKAP7

2.12e-04174754390bd41ef114464f3db3e0cac4e67fe7571b4c23
ToppCellASK452-Immune-NK_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLAMF7 BTN3A2 BTN3A1 FCRL6

2.12e-04174754b84e6dc1c003a677234ce3a818650ff58a45dd09
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAFD1 GBP1 LY96 BTN3A1

2.17e-0417575497616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B1|343B / Donor, Lineage, Cell class and subclass (all cells)

STK10 SLAMF7 BTN3A2 FCRL6

2.17e-04175754b1003230c39b2a9ceb43cb80728061d906ed0835
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R26 PTGFRN VPS53 CABLES1

2.21e-0417675476fdf211bce101e83a27d822cb399487bd107027
ComputationalNeighborhood of CASP8

STK10 BTN3A3 BTN3A2 BTN3A1

1.06e-0527564GNF2_CASP8
ComputationalNeighborhood of SNRK

STK10 BTN3A3 BTN3A2 BTN3A1

1.23e-0528564GNF2_SNRK
ComputationalNeighborhood of ITGAL

STK10 BTN3A3 BTN3A2 BTN3A1

1.85e-0455564GNF2_ITGAL
DrugMafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A

BICDL1 TRAFD1 MINK1 GBP1 RFXAP VPS53 BTN3A1 PDLIM5

2.80e-071977585499_UP
DrugPyrimethamine [58-14-0]; Down 200; 16uM; PC3; HT_HG-U133A

ITPKC BTN3A3 TLN1 MINK1 GBP1 BTN3A2 CAPN15

4.07e-061987574194_DN
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

DNAH3 AJAP1 MAP3K8 HDDC2 RUSF1 CAPN15 BIK

4.21e-061997571021_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

TNIK ATP1B1 BTN3A1 PDLIM5 ATP10D BIK

3.67e-051887561306_UP
DrugSalbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A

MINK1 VPS53 RUSF1 AKAP7 CAPN15 BIK

4.01e-051917567376_DN
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; PC3; HT_HG-U133A

TLN1 MINK1 GBP1 VPS53 PPP4R3A CAPN15

4.25e-051937564226_DN
DrugCefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A

BTN3A3 TLN1 MINK1 GBP1 PPP4R3A CAPN15

4.25e-051937564245_DN
DrugClemizole hydrochloride [1163-36-6]; Up 200; 11uM; HL60; HT_HG-U133A

MINK1 ATP10B ARHGEF11 VPS53 RUSF1 PDLIM5

4.63e-051967562339_UP
DrugBromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A

TNIK BICDL1 MINK1 ATP10B LTK RFXAP

4.77e-051977563617_UP
DrugSulmazole [73384-60-8]; Down 200; 14uM; PC3; HT_HG-U133A

ITPKC TLN1 GATB SLAMF7 ARHGEF11 RUSF1

4.77e-051977564009_DN
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

TNIK KDM5A MINK1 ATP10B BTN3A1 PDLIM5

4.77e-051977567504_DN
DrugHydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; PC3; HT_HG-U133A

TNIK ITPKC DNAH3 TRAFD1 GBP1 RUSF1

4.77e-051977567309_DN
DrugMephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A

STK10 BTN3A3 ARHGEF11 BTN3A1 AKAP7 CAPN15

4.90e-051987567384_DN
DrugSulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A

BICDL1 ELAPOR1 ATP10B TKTL1 SLAMF7 BTN3A2

4.90e-051987563218_UP
DrugTyloxapol [25301-02-4]; Down 200; 4uM; HL60; HT_HG-U133A

ITPKC KDM5A RFXAP BTN3A1 CAPN15 BIK

5.04e-051997563074_DN
Diseaseprogressive familial intrahepatic cholestasis (implicated_via_orthology)

ATP10B ATP10D

1.71e-053712DOID:0070221 (implicated_via_orthology)
Diseaseglucose metabolism decline measurement, cingulate cortex measurement

VPS53 PPP4R3A

2.03e-049712EFO_0007738, EFO_0009392
Diseaseepilepsy (implicated_via_orthology)

TNIK MINK1 ATP1B1 MAP4K4

6.54e-04163714DOID:1826 (implicated_via_orthology)
Diseasedevelopmental dysplasia of the hip

AJAP1 VPS53

6.70e-0416712EFO_1000648
Diseasedecreased susceptibility to hepatitis C infection

PTGFRN NDFIP1

6.70e-0416712EFO_0010101
Diseaseage of onset of asthma

LTK BTN3A2 NDFIP1

9.26e-0479713OBA_2001001
Diseasetriacylglycerol 48:2 measurement

ZPR1 VPS53

1.28e-0322712EFO_0010405
DiseaseTinnitus, wellbeing measurement

MAP3K8 GATB CAPN15

1.63e-0396713EFO_0007869, HP_0000360
DiseaseInhalant adrenergic use measurement

ATP10B BTN3A2 NDFIP1

1.63e-0396713EFO_0009941
Diseasecorpus callosum volume measurement

TNIK TLN1 PPP4R3A

1.83e-03100713EFO_0010299
Diseasetriacylglycerol 50:2 measurement

ZPR1 VPS53

2.54e-0331712EFO_0010409

Protein segments in the cluster

PeptideGeneStartEntry
TLDAEPMLAGCVARV

AMER3

666

Q8N944
LNMPLSEVCEGFDEE

CATSPERZ

41

Q9NTU4
AQRDDMIFEDCGDVP

ATP1B1

116

P05026
LAGELLAPVAAEAME

BIRC6

2416

Q9NR09
LAMVGEDADLPCHLF

BTN3A3

41

O00478
LAMVGEDADLPCHLF

BTN3A1

41

O00481
VDMPFATVDIQDDCG

AKAP7

36

Q9P0M2
MFQLAVDLPACEALG

AJAP1

31

Q9UKB5
DARGVLCEAQEAAMP

ARHGEF11

396

O15085
VLEPDMSCGEEAATA

GATB

221

O75879
LACIGDEMDVSLRAP

BIK

61

Q13323
ACCMELPAAAGDAVR

BICDL1

21

Q6ZP65
GADSVIMDLLEDPAC

ATP10B

791

O94823
ADMVLLFSTDPDGIC

ATP10D

191

Q9P241
EDLLADFEGPSIMDC

ITPKC

471

Q96DU7
IEHMICDTDPELGGA

PPP4R3A

431

Q6IN85
LDDMPENCICDVIGL

RADX

366

Q6NSI4
VLVDDMLPCDEAGCL

CAPN15

596

O75808
ITAIEMAEGAPPLCD

MAP4K4

221

O95819
SMDGAVCPLEELCDV

ALAS1

386

P13196
AMLDEECLRPGVVSD

MYO1A

451

Q9UBC5
PAADSCAIMEGEDVE

ELAPOR1

956

Q6UXG2
ADPAVGDMVQLLCEA

FCRL6

216

Q6DN72
EDIADDCSPGMRELI

MAP3K8

351

P41279
QLAECLCPEGMELAV

LTK

396

P29376
MALLSEGLDEVPAAC

FAM83D

1

Q9H4H8
AVIAALAICGIEMDE

PNPLA1

56

Q8N8W4
SGDLPCMENAVLALA

GBP1

306

P32455
CEFPIEAGDMFLEAL

PDLIM5

541

Q96HC4
LIFKMAADPECLDVG

KDM5A

616

P29375
AADPECLDVGLAAMV

KDM5A

621

P29375
MALALAALAAVEPAC

NDFIP1

1

Q9BT67
VCIPDDADMGTADSL

EIF2B3

76

Q9NR50
LCDVTLMPGDTDDAF

KLHL13

91

Q9P2N7
LAQEDCGLEEPTVAM

CABLES1

526

Q8TDN4
CEGDLAEAMPALEAA

DNAH3

2756

Q8TD57
AEAMPALEAALAALD

DNAH3

2761

Q8TD57
LAMVGEDADLPCHLF

BTN3A2

41

P78410
DAVLGVMDAARPEAA

CDC42EP5

101

Q6NZY7
EAISGSPEEMLFCLE

LY96

136

Q9Y6Y9
VHDMAECIVGDIAPA

HDDC2

76

Q7Z4H3
DCDNMRVTAFLDIPG

PPP4R1L

26

Q9P1A2
LNEDLAEMGCGPVDE

JADE3

151

Q92613
APCAALMAALAAAEP

HGH1

136

Q9BTY7
ITAIEMAEGAPPLCD

MINK1

221

Q8N4C8
EMVPGAADCNITADS

FUT5

96

Q11128
CIITVEGAALDPDDM

PTGFRN

711

Q9P2B2
MADDAGLETPLCSEQ

RUSF1

1

Q96GQ5
TEEGEFMACSPVALD

SOX11

21

P35716
DIKGAADEIMLPCEF

TRAFD1

281

O14545
EAGHCMEPESLVAIA

MOV10

646

Q9HCE1
EIDPICALQACMDGF

AHCYL1

341

O43865
SELPGLFDCEMLDAV

SIK2

901

Q9H0K1
LAVCGLVADFDPMGE

PPP1R26

96

Q5T8A7
LLVMQPCAGQDEAAA

RFXAP

46

O00287
ALFAEAACPEGQAME

MESP1

221

Q9BRJ9
DDERMLVEPACGAAL

SDSL

266

Q96GA7
VPCLASMIEDVLGEG

EIF4ENIF1

316

Q9NRA8
DCMEHAVLPVDGATL

CLUH

761

O75153
AMELAVECSFPVGEG

SLC49A3

361

Q6UXD7
EDPLAGMNALAAAAE

TNRC18

1336

O15417
CSVEIPELEFELGMA

ZPR1

331

O75312
ITAIEMAEGAPPLCD

TNIK

221

Q9UKE5
DPEEMAEDCNGAGLV

ZSCAN20

446

P17040
GLQSMSAPCVEADDA

NGFR

91

P08138
AQEACGPLEMDSALS

TLN1

1041

Q9Y490
RADAECPGMLESAEQ

STYXL2

76

Q5VZP5
CPGMLESAEQLLVED

STYXL2

81

Q5VZP5
PMLETDAEAGDSAQC

SOGA1

376

O94964
EFCPGGAVDAIMLEL

STK10

111

O94804
FRAALLEAGMPECTE

UBE2O

1276

Q9C0C9
EDGDVICLNSDDIMP

ROS1

2246

P08922
RAAASVMCHIEPDDG

TEX30

106

Q5JUR7
EGAADDPDSSMVLLC

SLAMF7

216

Q9NQ25
NDLDDPERGMIFVCS

SF3B3

276

Q15393
VQDLDAACDPALTAM

VPS53

606

Q5VIR6
MAAADGALPEAAALE

XPA

1

P23025
LQAATAGLEAAECPM

THAP11

211

Q96EK4
GIGEAVCAAVSMDPD

TKTL1

541

P51854