Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A5 PXDN SPON1 EMID1

2.52e-04188334GO:0005201
MousePhenoabnormal lens capsule morphology

PEX7 COL4A5 PXDN

8.02e-0620283MP:0003236
DomainEMI

UMODL1 EMID1

1.27e-0410322PF07546
DomainEMI_domain

UMODL1 EMID1

3.36e-0416322IPR011489
DomainEMI

UMODL1 EMID1

3.81e-0417322PS51041
DomainEGF_extracell

ADAM8 STAB1

4.73e-0360322IPR013111
DomainEGF_2

ADAM8 STAB1

4.73e-0360322PF07974
DomainEGF_3

ADAM8 UMODL1 STAB1

7.45e-03235323PS50026
DomainEGF

ADAM8 UMODL1 STAB1

7.45e-03235323SM00181
DomainEGF-like_dom

ADAM8 UMODL1 STAB1

8.73e-03249323IPR000742
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A5 PXDN

2.60e-0418192M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A5 PXDN

2.60e-0418192MM14882
PathwayWP_ETHER_LIPID_BIOSYNTHESIS

PEX7 ARSA

3.22e-0420192M46451
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

IRS2 KMT2D UNC45A ACACB UBR5 SEC16A

4.93e-0641837634709266
Pubmed

Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.

MARCHF7 UBR5

1.65e-05637225594175
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

COL4A5 PXDN SPON1 EMID1

2.99e-0516737422159717
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

ITPRID2 UNC45A PXDN SEC16A

6.28e-0520237433005030
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MAST1 SNPH PXDN UBR5 SEC16A

6.86e-0540737512693553
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

UBR5 SPON1 STAB1 SEC16A

9.53e-0522537412168954
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

COL4A5 IRS2 KMT2D EMID1 TMEM132A BAHCC1 SEC16A

1.43e-04110537735748872
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

KMT2D ITPRID2 UBR5 SEC16A

1.76e-0426437432814769
Pubmed

Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.

UNC45A UBR5 SEC16A

3.22e-0412537336030824
Pubmed

Identification of novel markers of mouse fetal ovary development.

M1AP ADAM8

3.52e-042637222844512
Pubmed

Interaction network of human early embryonic transcription factors.

KMT2D ACACB BAHCC1 SEC16A

5.18e-0435137438297188
Pubmed

Inceptor counteracts insulin signalling in β-cells to control glycaemia.

IRS2 ACACB

6.05e-043437233505018
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

ZSWIM8 IRS2 UBR5

7.49e-0416737325659891
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

COL4A5 MARCHF7 BAHCC1

7.89e-0417037315582152
Pubmed

Impact of WIN site inhibitor on the WDR5 interactome.

KMT2D UBR5

9.67e-044337233472061
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

KMT2D UBR5 SEC16A

9.92e-0418437332908313
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 SNPH ANK1 ACACB

8.93e-06163364b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 SNPH ANK1 ACACB

8.93e-06163364c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCellfacs-Marrow-KLS-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 SNPH ACACB SPACA1

9.15e-06164364d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

PXDN SPON1 EMID1 BAHCC1

9.37e-061653647b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SNPH ANK1 ADAM8 PNPO

1.01e-051683648f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

KCNN2 SNPH PXDN EMID1

1.38e-051823648b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A5 PXDN CSMD2 EMID1

1.57e-05188364997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 CSMD2 UMODL1 SPON1

1.70e-0519236425460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNN2 PXDN EMID1

2.08e-0414336327e06327f96cb72bd111ea6ece6307e5ebb3a146
ToppCellE15.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

M1AP ANK1 PNPO

2.08e-04143363e4207ff9e8248813356631631bbf31a63f23ad3c
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNN2 PXDN EMID1

2.08e-041433634edef95ae2a1ef4fc4b0d4fadf75bfc54b583932
ToppCellE15.5-Hematopoietic-Erythroid|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

M1AP ANK1 PNPO

2.08e-0414336315a7b93c381ef0f455f99f3abf4b2b9454d35bc4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAST1 ITPRID2 SPON1

2.17e-04145363b961b69befb15ff6f58635e0d4bda88ea732a346
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor|bone_marrow / Manually curated celltypes from each tissue

UMODL1 EMID1 BAHCC1

2.35e-04149363078e1e5765e476ba85c23fb8f6892b6698cbcbdb
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

ANK1 CSMD2 PNPO

2.54e-04153363654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

ANK1 CSMD2 PNPO

2.54e-04153363105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ADAM8 FAM157C TMEM132A

2.63e-04155363cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

PXDN UMODL1 BAHCC1

2.68e-04156363b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A5 ARSA PXDN

2.73e-04157363ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A5 ARSA PXDN

2.73e-04157363c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCellCOPD-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

PXDN ADAM8 TMEM132A

2.79e-041583638f66979e92f886d86cecbd26aaa0c5915c049734
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAST1 SNPH SVOPL

3.00e-04162363e73c644ce1db34f1d390878954e86fa0b3a455a1
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A5 PXDN TMEM132A

3.00e-0416236357d627259d27f39885bf416d74bcb6656db6e27b
ToppCellLPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNN2 SNPH BAHCC1

3.05e-041633636b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 ADAM8 PNPO

3.11e-04164363f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 ADAM8 TMEM132A

3.11e-0416436378de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCelllymphoid-B_cell-pro-B|lymphoid / Lineage, cell class and subclass

PXDN EMID1 BAHCC1

3.16e-041653638126c2f7810fc6e09b18783aadf6434ae12b0514
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK1 ADAM8 TMEM132A

3.16e-04165363c39f0479955c4e23921f7a450d3bc251a002200f
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

UMODL1 EMID1 BAHCC1

3.28e-04167363cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

PXDN SPON1 STAB1

3.34e-04168363aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PXDN ADAM8 SPON1

3.34e-041683633fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAST1 CSMD2 FAM13C

3.34e-04168363327b02f19f4a8607c033203824fdc60a1254331f
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PXDN ANK1 ADAM8

3.39e-041693630425d2580ed325178f522c0093ff4623de6ce7a8
ToppCellAdult-Immune-enucleated_erythrocyte-D122|Adult / Lineage, Cell type, age group and donor

ANK1 ADAM8 EMID1

3.39e-04169363d5624e5b3687bd3f18f3a2b47a94d11eb1fbdb75
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PXDN ANK1 ADAM8

3.39e-04169363fec669968a77060bd77ee8695034e35a642c984f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PXDN ANK1 EMID1

3.45e-0417036336dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

ANK1 SVOPL EMID1

3.51e-041713633ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SKOR1 MAST1 ANK1

3.51e-0417136399176a932569fa1c7e1c01009684f5a65244b96e
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A5 FAM13C SPON1

3.63e-041733631f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM8 SVOPL EMID1

3.70e-0417436364d13a7a9757e85f4f4af876c687dd18a7efa01a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

M1AP ADAM8 BAHCC1

3.70e-041743637be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

EMID1 BAHCC1 STAB1

3.70e-04174363029394e107bf7ad58056d2216070aa2e964fff12
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PXDN SPON1 EMID1

3.70e-04174363f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

M1AP ADAM8 SVOPL

3.70e-0417436336080fa12497faa752ff07ae52cd3864053eafef
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

M1AP ADAM8 BAHCC1

3.76e-041753631b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

PXDN CSMD2 SPON1

3.82e-04176363852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PXDN CSMD2 SPON1

3.82e-04176363d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

IRS2 ACACB SPON1

3.95e-04178363278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARSA PNPO STAB1

3.95e-0417836330d2b54462fd16222ad2e3806be6143e834b29e0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PXDN ANK1 EMID1

3.95e-041783632a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADAM8 SVOPL EMID1

4.01e-04179363810972561d1ae5a68389b54ceeac7a49890513a4
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK1 SVOPL EMID1

4.08e-04180363f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PXDN FAM13C STAB1

4.08e-0418036379c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK1 SVOPL EMID1

4.08e-04180363b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITPRID2 CSMD2 FAM13C

4.15e-041813632b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITPRID2 CSMD2 FAM13C

4.15e-041813636aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A5 FAM13C SPON1

4.15e-0418136325915e2500430a902db37d79a749ce2990b69810
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITPRID2 CSMD2 FAM13C

4.15e-0418136340df0afcb6848202da54670e84f22d7c3a515d01
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.15e-041813630c3f469bed108994ed696230e3c30343f7a301d3
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITPRID2 CSMD2 FAM13C

4.15e-0418136340d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PXDN ANK1 EMID1

4.21e-04182363d3a037268f026eb2f84428b1821022503cef7756
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN2 SPON1 EMID1

4.28e-0418336399bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

ANK1 SVOPL EMID1

4.35e-04184363b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

FAM157A IRS2 FAM157C

4.35e-04184363ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PXDN ANK1 EMID1

4.42e-041853630b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACACB EMID1 STAB1

4.42e-0418536359acaf025353405948dc34ccccf37ec5c08ea903
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.49e-0418636341e03be964044dae690d566bd078dab3d8045eba
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

ANK1 SVOPL EMID1

4.49e-0418636359c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

KCNN2 PXDN TMEM132A

4.49e-041863632e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

KCNN2 PXDN TMEM132A

4.49e-04186363c3449e54454009973818fc1101933c6f0168258c
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

KCNN2 PXDN TMEM132A

4.49e-04186363f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

KCNN2 PXDN TMEM132A

4.49e-041863632b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.56e-04187363401be371b32066db926de3415bb4ce9465749dc3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.56e-041873635c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.56e-0418736393c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST1 ANK1 TMEM132A

4.56e-041873631b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.56e-041873635d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK1 SVOPL EMID1

4.70e-0418936356156325cc36b1329bf483f81bb74f371ef15e20
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PXDN SPON1 EMID1

4.70e-0418936371397e993a77d70b2eeede240bdfc7660b558987
ToppCellIPF-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

FAM157A IRS2 FAM157C

4.70e-04189363ad7bb3a7de8e48c145e4382f90d30bb2159c2b76
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PXDN SPON1 EMID1

4.70e-041893634eea4759520c312bd17a681034d8074e47093d2b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SKOR1 ANK1 TMEM132A

4.70e-04189363f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

FAM157A UMODL1 FAM157C

4.70e-041893635c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

FAM157A UMODL1 FAM157C

4.78e-04190363ed978cd5d9da87b49878a330e362762c487f849f
ToppCellIPF-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

FAM157A IRS2 FAM157C

4.78e-04190363ffa890138394f579fee53fcfac6c121bf86adc26
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.78e-041903635c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.78e-041903633a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellIPF-Myeloid-cMonocyte|IPF / Disease state, Lineage and Cell class

FAM157A IRS2 FAM157C

4.78e-04190363a099f51f2b7618b6712af38eedd5ee64d8663a4a
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

FAM157A UMODL1 FAM157C

4.78e-04190363f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.78e-04190363b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZSWIM8 KMT2D ADAM8

4.78e-041903633f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACACB BAHCC1 STAB1

4.78e-0419036363018acb7ad80415e861643162abdc2e55968ee4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A5 ACACB SPON1

4.78e-041903632de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.78e-041903631c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PXDN SPON1 EMID1

4.92e-041923639093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM8 SVOPL EMID1

4.92e-04192363758ca0dacf313787effda36e6d1adb809e5b3a4e
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.92e-04192363f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PXDN SPON1 EMID1

4.92e-041923639ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

ANK1 SVOPL EMID1

4.92e-04192363cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SPON1 EMID1

4.92e-0419236343beaac1de99b9c1a6dab4a450b4e81286987b64
Diseasegastric adenocarcinoma (is_implicated_in)

KMT2D UBR5

7.47e-0511352DOID:3717 (is_implicated_in)
Diseasecoronary aneurysm

KCNN2 CSMD2

7.94e-0435352EFO_1000881
Diseaseleft ventricular systolic function measurement

PXDN SPON1

1.25e-0344352EFO_0008206
Diseasecongenital heart disease

KCNN2 DCAF4L2

2.24e-0359352EFO_0005207
DiseaseInsulin Sensitivity

IRS2 ACACB

2.32e-0360352C0920563
DiseaseInsulin Resistance

IRS2 ACACB

2.32e-0360352C0021655
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

IRS2 ACACB

2.71e-0365352DOID:0080208 (biomarker_via_orthology)
Diseasemetabolite measurement

ARSA MPV17L2 SVOPL STAB1

4.22e-03560354EFO_0004725

Protein segments in the cluster

PeptideGeneStartEntry
LFFRMVRGSLPATMC

UMODL1

821

Q5DID0
SSRLMGSSPASSFMG

BAHCC1

61

Q9P281
TSRMMGRFSGSELPS

CSMD2

2031

Q7Z408
SFMVDARGGSMRGSR

ANK1

916

P16157
RCIMAGSIGSSFPRM

ADAM8

361

P78325
DSGFSPLCQRMGAMV

ACACB

1356

O00763
RSASMFAVGCSMGPF

MPV17L2

61

Q567V2
LACSLMGPSRMSLFS

M1AP

51

Q8TC57
MSSCRYNGGVMRPLS

KCNN2

1

Q9H2S1
GSFPGMRRPGMLCSF

DCAF4L2

166

Q8NA75
GCGRPSSNKMLRSMG

FAM157A

126

C9JC47
MSAVCGGAARMLRTP

PEX7

1

O00628
CGRPSSNKMLRSMGG

FAM157C

131

P0CG43
DNGPETMRMSRGGCS

ARSA

281

P15289
CGRSAAMDLGPMRKS

PNPO

26

Q9NVS9
PFRSSALMGMCGSRS

ITPRID2

1041

P28290
SFPGGSMFRRTKSCR

MAST1

16

Q9Y2H9
GYMTMDRPLSHCGRS

IRS2

541

Q9Y4H2
MRATFSGSAGRLCPS

IRS2

601

Q9Y4H2
AGSCLRRFSTMPFMF

COL4A5

1506

P29400
PSSSLSARMMSGSRG

MARCHF7

16

Q9H992
MRRMALRPTAFSGCL

EMID1

121

Q96A84
MSPRGTGCSAGLLMT

SPACA1

1

Q9HBV2
ASMDAGMRRTRPGTS

POM121L1P

356

Q3SYA9
AGAMPISSRRCGMIT

SKOR1

141

P84550
SPCSISCGMGMRSRE

SPON1

511

Q9HCB6
MCARMAGRTTAAPRG

TMEM132A

1

Q24JP5
SIGSMMRALAGTYRC

KIR3DS1

181

Q14943
FMMPRSSSRCSCGDG

FAM13C

266

Q8NE31
MAMSLPGSRRTSAGS

SNPH

1

O15079
TMRALGMGTSGSLCR

SVOPL

426

Q8N434
LMSGRMPAASTCCGD

SEC16A

1681

O15027
MFFVRSSPVCGSGMT

PXDN

876

Q92626
SSPCSDRGVCMDGMS

STAB1

1976

Q9NY15
IRSARSAFCLTPMGM

ZSWIM8

1791

A7E2V4
GLAMLTSMRPTLCSR

UNC45A

841

Q9H3U1
ARGMTPFMSAVSGRA

UBR5

1111

O95071
MGSRDTRMGTGPFSS

KMT2D

3161

O14686