Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionCCR4-NOT complex binding

MARF1 GARRE1

1.84e-053502GO:1905762
PathwayBIOCARTA_PPARG_PATHWAY

PPARGC1A MED1

1.47e-047382MM1573
PathwayBIOCARTA_PPARG_PATHWAY

PPARGC1A MED1

1.96e-048382M22058
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRANK1 MYO6 MCF2L KAT6B GARRE1

5.04e-071045259205841
Pubmed

Therapeutic potential of ginsenoside Rg3 and Rf for Huntington's disease.

PPARGC1A HTT

2.19e-06252234128157
Pubmed

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

PPARGC1A HTT

2.19e-06252217018277
Pubmed

Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex.

PPARGC1A MED1

6.57e-06352224458359
Pubmed

Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.

PPARGC1A HTT

1.31e-05452227008868
Pubmed

Recurrent activating mutations of PPARγ associated with luminal bladder tumors.

PPARGC1A MED1

1.31e-05452230651555
Pubmed

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis.

MYO6 HTT

2.19e-05552215837803
Pubmed

A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.

PPARGC1A MED1

2.19e-05552215026545
Pubmed

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.

PPARGC1A MED1

2.19e-05552217011503
Pubmed

Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis.

PPARGC1A TLR2

2.19e-05552220657826
Pubmed

Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor γ (PPARγ) modulators.

PPARGC1A MED1

2.19e-05552222070604
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ANKRD36B NUSAP1 CDSN MYO6 ZNF451 MARF1 TNRC6B MED1 RRBP1 DCUN1D3

3.06e-051371521036244648
Pubmed

The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.

PPARGC1A MED1

3.28e-05652217468099
Pubmed

Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene.

PPARGC1A MED1

3.28e-05652219782026
Pubmed

Amino acids important for ligand specificity of the human constitutive androstane receptor.

PPARGC1A MED1

3.28e-05652215572376
Pubmed

Human transcription factor protein interaction networks.

TRERF1 NUSAP1 UBE2O MYO6 ZNF451 UBR4 MARF1 TNRC6B HERC1 GARRE1

4.35e-051429521035140242
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ANKRD36B WDR64 MYO6 UBR4 REV3L MED1 MCF2L

4.42e-0563852731182584
Pubmed

S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.

PPARGC1A MED1

4.58e-05752217704298
Pubmed

Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.

UBE2O MYO6 UBR4

5.88e-055052317550899
Pubmed

Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.

PPARGC1A MED1

6.10e-05852223178929
Pubmed

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

PPARGC1A MED1

7.84e-05952214636573
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

PTPN13 MYO6 DOCK11 MARF1 TNRC6B MED1 RRBP1

9.76e-0572452736232890
Pubmed

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.

PPARGC1A MED1

9.79e-051052230595551
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATRN UBE2O PTPN13 MYO6 ZNF451 UBR4 ANKRD36 REV3L RRBP1

1.10e-04128552935914814
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

PPARGC1A MED1

1.20e-041152215681609
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBE2O TRANK1 TOPBP1 RRBP1 KAT6B GARRE1

1.35e-0452952614621295
Pubmed

A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis.

PPARGC1A TLR2

1.43e-041252221966468
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

PPARGC1A MED1

1.43e-041252212189208
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

UBE2O PTPN13 OSBPL11 TNRC6B MED1 HTT

1.66e-0454952638280479
Pubmed

Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues.

PPARGC1A MED1

1.69e-041352233888560
Pubmed

Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles.

TLR2 IL17RC

1.69e-041352230824326
Pubmed

Pigmentation-related genes and their implication in malignant melanoma susceptibility.

ATRN HPS1

1.97e-041452219320733
Pubmed

Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.

MED1 HTT

2.60e-041652227721240
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

UBE2O PTPN13 TNRC6B RRBP1

2.74e-0420952436779422
Pubmed

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.

PPARGC1A MED1

2.94e-041752228291835
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATRN ABCB9 UBR4

3.06e-048752312465718
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

PPARGC1A MED1

4.52e-042152219596656
Pubmed

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.

TNRC6B RRBP1

4.52e-042152233029523
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

UBE2O PTPN13 MYO6 OSBPL11 TNRC6B MED1 RRBP1

4.60e-0493452733916271
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

ATRN SYCP2 MYO6

4.60e-0410052326073538
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ANKRD36B ANKRD36 WNK3

4.74e-0410152310997877
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

CDSN MYO6 ZNF451 TNRC6B MED1

5.26e-0444452534795231
Pubmed

The association of innate immune response gene polymorphisms and puerperal group A streptococcal sepsis.

MYLK TLR2

5.44e-042352220207250
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRERF1 MPP2 UBE2O DOCK11 UBR4 TNRC6B WNK3

5.52e-0496352728671696
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

UBE2O PTPN13 MYO6 TNRC6B

6.51e-0426352434702444
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

DOCK11 UBR4 TNRC6B MCF2L HTT

7.13e-0447552531040226
Pubmed

Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.

PPARGC1A MED1

8.08e-042852228159809
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TRANK1 MYO6 DOCK11 HERC1 RRBP1

8.73e-0449752536774506
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 ABCB9 OSBPL11 MED1 RRBP1 KAT6B

1.02e-0377452615302935
Pubmed

The DNA sequence and comparative analysis of human chromosome 20.

ATRN SEMG2 SYCP2 BCAS1 RRBP1

1.04e-0351752511780052
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NUSAP1 FAM184B PPARGC1A PTPN13 HPS1 OSBPL11 HERC1

1.10e-03108452711544199
Pubmed

TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.

UBR4 MED1

1.12e-033352233567268
Pubmed

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.

NUSAP1 PPARGC1A

1.49e-033852238196272
Cytoband3q21

MYLK OSBPL11

3.29e-04245123q21
Cytoband2q11.2

ANKRD36B ANKRD36

2.94e-03725122q11.2
CoexpressionAIZARANI_LIVER_C9_LSECS_1

MYO6 ZNF451 HERC1 RRBP1 MCF2L GARRE1

2.69e-05304516M39113
CoexpressionMTOR_UP.N4.V1_DN

ANKRD36B MARF1 TNRC6B GALNT6 GARRE1

2.92e-05184515M2756
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ATRN JARID2 PTPN13 ZNF451 TOPBP1 REV3L MED1 KAT6B GARRE1

3.60e-05856519M4500
CoexpressionGSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP

SYCP2 PTPN13 P2RX5 UBR4 HTT

3.67e-05193515M9056
CoexpressionGSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN

TRERF1 TOPBP1 OSBPL11 MED1 GARRE1

4.24e-05199515M3177
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN

ANKRD36B GAS2L1 HPS1 MARF1 TNRC6B

4.24e-05199515M8861
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

PTPN13 ZNF451 UBR4 ANKRD36 HERC1

4.35e-05200515M9889
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

MARF1 TNRC6B HERC1 KAT6B CSMD3

1.81e-06177515e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TRANK1 MYLK MARF1 OSBPL11 MED1

2.30e-0618651503db813598b67b1e08f759758a1c2023396921fa
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB9 BCAS1 GALNT6 RRBP1 MCF2L

2.76e-061935156a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

TLR2 TNRC6B ANKRD36 BCAS1 REV3L

3.21e-06199515c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCelldroplet-Heart-nan-18m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 UBE2O ANKRD36 GALNT6

5.51e-06101514af4a84e4993d4e80c834e1591556b3b3781deaf3
ToppCelldroplet-Heart-nan-18m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 UBE2O ABCB9 ANKRD36

6.19e-06104514060f0baca239ab89c18be40c1aa31931f4791b62
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

NUSAP1 MYLK MYO6 ANKRD36

2.56e-05149514651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MPP2 CDSN PTPN13 MYO6

3.30e-0515951450d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANKRD36B ABCB9 ANKRD36 RRBP1

4.09e-05168514f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCelldroplet-Marrow-BM_(NON-STC)|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 UBE2O ANKRD36 HERC1

4.48e-051725146004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 UBE2O ANKRD36 HERC1

4.48e-0517251431c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ANKRD36B TNRC6B ANKRD36 HERC1

5.46e-05181514f2315414e714ac86211546a935660c4be6e85f1b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A SYCP2 TRANK1 CSMD3

5.82e-051845142cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A SYCP2 TRANK1 CSMD3

5.82e-05184514ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A SYCP2 TRANK1 CSMD3

5.82e-051845142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ANKRD36 GALNT6 RRBP1

5.82e-0518451401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MPP2 PPARGC1A MCF2L WNK3

5.95e-05185514c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM184B BCAS1 SPATS1 CSMD3

6.33e-051885148385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM184B PPARGC1A CDSN BCAS1

6.33e-05188514c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM184B PPARGC1A CDSN BCAS1

6.33e-051885143b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM184B BCAS1 SPATS1 CSMD3

6.33e-05188514cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB9 BCAS1 GALNT6 RRBP1

6.46e-051895145a0fd34928117f162c83ca1b068aa8f7069a6765
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ANKRD36 GALNT6 RRBP1

6.59e-0519051423f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM184B BCAS1 SPATS1 CSMD3

6.59e-05190514e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ANKRD36 GALNT6 RRBP1

6.59e-051905143c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ATRN JARID2 TNRC6B RRBP1

6.87e-05192514916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID-19_Severe-Plasmablast|World / disease group, cell group and cell class

NUSAP1 ABCB9 P2RX5 RRBP1

6.87e-05192514a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ATRN JARID2 TNRC6B RRBP1

7.01e-05193514e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANKRD36B TRANK1 KAT6B DCUN1D3

7.29e-0519551483c125223e7ca0f08a31414b3a16347912564765
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

SYCP2 MYO6 ANKRD36 RRBP1

7.58e-051975140fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN MYO6 BCAS1 GALNT6

7.73e-0519851427f0654fb0857e93f030e1a4b1c307b31576bbcd
ToppCellMS-Multiple_Sclerosis-Lymphocyte-B-Plasmablast|Multiple_Sclerosis / Disease, condition lineage and cell class

NUSAP1 ABCB9 P2RX5 RRBP1

7.73e-05198514c30b71b998acde080adb90a2016a165c5ed17a81
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD36B ANKRD36 HERC1 CSMD3

7.73e-051985140ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JARID2 DOCK11 UBR4 TLR2

7.89e-05199514379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PTPN13 ABCB9 RRBP1 WNK3

7.89e-05199514121de4e02585de3a3010398387c523bacf8ce546
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN MYO6 BCAS1 RRBP1

8.04e-05200514fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ANKRD36B ANKRD36 GALNT6 RRBP1

8.04e-05200514292c63693eb7f435335a8cfba07aa35b72139393
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPARGC1A GALNT6 RRBP1 MCF2L

8.04e-05200514030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO6 BCAS1 GALNT6 MCF2L

8.04e-05200514d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

ANKRD36B ANKRD36 HERC1 CSMD3

8.04e-0520051448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN MYO6 BCAS1 RRBP1

8.04e-05200514f0c338877e39226a90c4effe12f6501d33542a73
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BCAS1 GALNT6 RRBP1 MCF2L

8.04e-052005140eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BCAS1 GALNT6 RRBP1 MCF2L

8.04e-0520051485c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 UBE2O ANKRD36

1.76e-0495513756d76830b8e7e8903b2bc7a39a38880be684297
DrugPipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A

MPP2 PTPN13 ABCB9 HPS1 TNRC6B BCAS1

4.24e-061955066821_DN
Drug5-(3-((3-(5-methoxybenzisoxazol-3-yl)benzimidazol-1-yl)methyl)phenyl)-5-methyloxazolidinedione

PPARGC1A MED1

1.42e-053502ctd:C570539
DrugSB219994

PPARGC1A MED1

2.83e-054502ctd:C480767
DrugLY117018

PPARGC1A PTPN13 MED1

3.50e-0529503CID000104946
DrugTCDF

PPARGC1A CDSN MED1

5.68e-0534503CID000039929
DrugTrifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A

MYLK ABCB9 TLR2 RRBP1 MCF2L

5.70e-051885055442_UP
Druglomustine; Down 200; 100uM; MCF7; HT_HG-U133A

MPP2 SYCP2 ABCB9 HPS1 KAT6B

6.62e-051945057089_DN
Drug5252917; Down 200; 14uM; MCF7; HT_HG-U133A_EA

MPP2 HPS1 MED1 RRBP1 KAT6B

6.78e-05195505944_DN
DrugNS-398; Down 200; 10uM; PC3; HT_HG-U133A

MPP2 ABCB9 IL17RC MED1 MCF2L

6.78e-051955056892_DN
DrugNiflumic acid [4394-00-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A

ATRN PTPN13 BCAS1 MCF2L GARRE1

6.95e-051965057430_DN
DrugEsculetin [305-01-1]; Up 200; 22.4uM; HL60; HT_HG-U133A

SYCP2 TRANK1 MYLK IL17RC RRBP1

7.12e-051975053120_UP
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; PC3; HT_HG-U133A

SEMG2 GAS2L1 SYCP2 TLR2 MCF2L

7.29e-051985054470_UP
DrugBromperidol [10457-90-6]; Up 200; 9.6uM; HL60; HG-U133A

GAS2L1 HPS1 OSBPL11 KAT6B HTT

7.29e-051985051723_UP
Drug5211181; Down 200; 12uM; MCF7; HT_HG-U133A_EA

MPP2 HPS1 TNRC6B RRBP1 KAT6B

7.29e-05198505950_DN
DrugN6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA

MPP2 HPS1 TNRC6B RRBP1 KAT6B

7.47e-05199505959_DN
Diseaseosteoarthritis

MPP2 MYLK MCF2L CSMD3

5.07e-04222494MONDO_0005178
DiseaseHuntington's disease (is_implicated_in)

PPARGC1A HTT

6.68e-0423492DOID:12858 (is_implicated_in)
Diseaseresponse to TNF antagonist, joint damage measurement

MPP2 CSMD3

7.91e-0425492EFO_0004653, EFO_0005413
DiseaseDrug habituation

FAM184B MYO6 CSMD3

9.32e-04115493C0013170
DiseaseSubstance-Related Disorders

FAM184B MYO6 CSMD3

9.32e-04115493C0236969
DiseaseDrug abuse

FAM184B MYO6 CSMD3

9.32e-04115493C0013146
DiseaseDrug Use Disorders

FAM184B MYO6 CSMD3

9.32e-04115493C0013222
DiseaseDrug Dependence

FAM184B MYO6 CSMD3

9.32e-04115493C1510472
DiseaseSubstance Dependence

FAM184B MYO6 CSMD3

9.32e-04115493C0038580
DiseaseSubstance Use Disorders

FAM184B MYO6 CSMD3

9.32e-04115493C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

FAM184B MYO6 CSMD3

9.32e-04115493C0029231
DiseasePrescription Drug Abuse

FAM184B MYO6 CSMD3

9.32e-04115493C4316881
DiseaseSubstance abuse problem

FAM184B MYO6 CSMD3

9.56e-04116493C0740858
DiseaseHuntington's disease (implicated_via_orthology)

PPARGC1A HTT

1.30e-0332492DOID:12858 (implicated_via_orthology)
DiseaseTinnitus

MPP2 PTPN13 TNRC6B

1.33e-03130493HP_0000360
Diseasebreast cancer (is_implicated_in)

PTPN13 TLR2 KAT6B

2.00e-03150493DOID:1612 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
KTCGSNLQGPSGTFT

CSMD3

546

Q7Z407
GGKSGTVSSQKQPAS

ANKRD36

641

A6QL64
GGKSGTVSSQKQPAS

ANKRD36B

351

Q8N2N9
GKIILQPCGSKSSSS

CDSN

441

Q15517
TAKGTQTGKSQCLLG

C6orf201

121

Q7Z4U5
TKCKNPSSTLGSKNG

DCUN1D3

6

Q8IWE4
GTFPKSAKGSRGSCN

KAT6B

86

Q8WYB5
AAKSKNCSSPQRGGS

MYLK

291

Q15746
QTGCGSSKGAEKGLQ

ERVS71-1

111

P61550
EKQKSSGLNLCTGTG

NADK2

301

Q4G0N4
TDPSNTGKGKCIEGS

ATRN

1006

O75882
NSKINPPGTCQGSKA

FAM184B

6

Q9ULE4
QCGQGNSTGPITKPK

HERC1

696

Q15751
LSGKKSISLAGCGTQ

OR2M4

86

Q96R27
GGPGNQTKDSSKTTI

KRT27

406

Q7Z3Y8
LTPNSGTLCGSLSGK

MPP2

326

Q14168
CGPASQSTLGLKGSL

NUSAP1

256

Q9BXS6
SSGTQGNNSTKKGPE

PPARGC1A

336

Q9UBK2
PLKCQKQRGASTSSG

FAM157B

336

P0CG42
GGGSSCSPVLSRKQK

HTT

426

P42858
SSSLCSQKGGVIKQG

DOCK11

156

Q5JSL3
SSSSLSVLGGKCGQP

GAS2L1

566

Q99501
NSGSGTCLTSQDKKP

GALNT6

591

Q8NCL4
PSGNGNKSSGGLQKT

GARRE1

521

O15063
AKATPGKGSQANSGS

MARF1

626

Q9Y4F3
GPSGSAQCLSSSGKA

MCF2L

1116

O15068
CSQKTSSELGKGPLA

HPS1

561

Q92902
AGKNSKGCNPSGHTQ

BCAS1

336

O75363
GGSGNTEPQKKGLSC

IL17RC

96

Q8NAC3
SQSKNSSQSGGKPGS

MED1

1141

Q15648
PKSTKGNGSYSVGSC

PTPN13

1981

Q12923
VTPNKNSSCGGGISS

OSBPL11

26

Q9BXB4
SGKNGSIENCLSKPT

JARID2

1201

Q92833
GSSSQKGNGSVCPQL

P2RX5

401

Q93086
QGNSPSGKGLSSQCS

SEMG2

146

Q02383
ALVGPSGSGKSSCVN

ABCB9

536

Q9NP78
PGLKTGTINCGTKSS

ZNF451

141

Q9Y4E5
GAKGNTPATGTTQGK

RRBP1

186

Q9P2E9
SGQGVVNKGSSNSPK

REV3L

1971

O60673
SKGCFANTTPSGKSV

SPATS1

56

Q496A3
SNSGVGGTIKSPKNN

SYCP2

1151

Q9BX26
ASVGKPSGGLCSSKN

ZNF556

401

Q9HAH1
QQCGGKPGVTFTSAK

UBE2O

911

Q9C0C9
KPCSSNTSKGQGEKI

ZNF625

291

Q96I27
KSQGSFKSVPCGATA

TRANK1

636

O15050
IKSSNGGSKTSPALC

UBR4

2151

Q5T4S7
CKGSSGSLNSIPSGL

TLR2

36

O60603
SAPSNGSGKNDSKGV

TOPBP1

1046

Q92547
LPGSTTSNKGKGSQC

TNRC6B

231

Q9UPQ9
CESSKGPQSSKGSKQ

WDR64

731

B1ANS9
KPGGTQSGYCSVKSS

TRERF1

1056

Q96PN7
GSGKSVAKTGPESNQ

WNK3

1481

Q9BYP7
GSTSGGCNLKNKSAQ

MYO6

356

Q9UM54