Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ATP13A4 MYH9 PSMC4 RAD54L2 KATNA1 MORC2 ARID1A BLM STARD9 MACF1 POLQ DNAH6 ATP2B1	4.04e-05	614	112	13	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP13A4 PSMC4 RAD54L2 KATNA1 MORC2 BLM MACF1 POLQ DNAH6 ATP2B1	1.90e-04	441	112	10	GO:0016887
GeneOntologyMolecularFunction	actin filament binding	MYH9 SYNE1 PANX1 ERMN XIRP2 MACF1 TLN2	2.95e-04	227	112	7	GO:0051015
GeneOntologyMolecularFunction	transcription coactivator activity	NCOA2 KDM5A CAMTA2 ACTL6A ARID1A KMT2C MED7 MED13	3.11e-04	303	112	8	GO:0003713
GeneOntologyMolecularFunction	actin binding	MYH9 SYNE1 PANX1 ERMN XIRP2 PHACTR3 MACF1 TLN2 DIAPH3 PALLD	3.66e-04	479	112	10	GO:0003779
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	CUL2 RGPD8 KCMF1 UBR4 HECTD4 RGPD1 FBXO30 UBR5 UBR3 MED7	6.15e-04	512	112	10	GO:0019787
GeneOntologyMolecularFunction	alpha-actinin binding	CACNA1C XIRP2 PALLD	6.89e-04	31	112	3	GO:0051393
GeneOntologyMolecularFunction	aminoacyltransferase activity	CUL2 RGPD8 KCMF1 UBR4 HECTD4 RGPD1 FBXO30 UBR5 UBR3 MED7	8.25e-04	532	112	10	GO:0016755
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1B KMT2C	8.54e-04	8	112	2	GO:0140945
GeneOntologyMolecularFunction	potassium:chloride symporter activity	SLC12A1 SLC12A7	1.09e-03	9	112	2	GO:0015379
GeneOntologyMolecularFunction	cytoskeletal protein binding	VAPA CACNA1C MYH9 SYNE1 PANX1 KATNA1 MAP10 ERMN XIRP2 STARD9 PHACTR3 MACF1 TLN2 DIAPH3 PALLD	1.22e-03	1099	112	15	GO:0008092
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1C ATP13A4 SLC11A2 PANX1 SLC12A1 SLC12A7 ATP2B1 SLC30A10 SLC4A9	1.23e-03	465	112	9	GO:0046873
GeneOntologyMolecularFunction	acyltransferase activity	CUL2 RGPD8 KCMF1 UBR4 HECTD4 RGPD1 FBXO30 KMT2C UBR5 SCP2 UBR3 MED7	1.36e-03	775	112	12	GO:0016746
GeneOntologyMolecularFunction	manganese ion transmembrane transporter activity	SLC11A2 SLC30A10	1.36e-03	10	112	2	GO:0005384
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1B KMT2C	1.36e-03	10	112	2	GO:0140999
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	ATP13A4 SLC11A2 SLC12A1 SLC12A7 ATP2B1 SLC30A10 SLC4A9	1.55e-03	301	112	7	GO:0022853
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1C ATP13A4 PANX1 ATP2B1 SLC30A10	1.62e-03	151	112	5	GO:0015085
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP13A4 ATP2B1	1.66e-03	11	112	2	GO:0005388
GeneOntologyMolecularFunction	actinin binding	CACNA1C XIRP2 PALLD	1.80e-03	43	112	3	GO:0042805
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RGPD8 KCMF1 UBR4 RGPD1 FBXO30 UBR5 UBR3 MED7	1.82e-03	398	112	8	GO:0061659
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	NCOA2 CUL2 MYH9 KDM5A SYNE1 KSR2 CAMTA2 ACTL6A RAD54L2 ARID1A STAP1 AKAP12 KMT2C MED7 MED13	2.08e-03	1160	112	15	GO:0030674
MousePheno	left sided brachiocephalic trunk	MORC2 PRRC2B	4.10e-05	2	90	2	MP:0013953
MousePheno	embryonic lethality before implantation, complete penetrance	RGPD8 RGPD1 PSMC4 ZNF407 XAB2 SF3B1 UBR3 ATP2B1	4.82e-05	203	90	8	MP:0011094
MousePheno	abnormal extraembryonic tissue morphology	NCOA2 CACNA1C MYH9 UBR4 FRYL RAD54L2 MORC2 ARID1A SNX13 UBR5 USP7 C3 SCFD1 ATP2B1 KDM6A PRRC2B TP53BP2	5.82e-05	908	90	17	MP:0002086
MousePheno	embryonic lethality prior to organogenesis, complete penetrance	MYH9 RGPD8 RGPD1 PSMC4 ZNF407 RAD54L2 ARID1A SLC2A3 XAB2 SF3B1 USP7 UBR3 MACF1 SCFD1 ATP2B1	1.12e-04	772	90	15	MP:0014259
MousePheno	embryonic lethality prior to tooth bud stage, complete penetrance	MYH9 RGPD8 RGPD1 PSMC4 ZNF407 RAD54L2 ARID1A SLC2A3 XAB2 SF3B1 USP7 UBR3 MACF1 SCFD1 ATP2B1	1.24e-04	779	90	15	MP:0014257
MousePheno	abnormal embryo development	MYH9 SETD1B RGPD8 RBMS1 UBR4 RGPD1 PSMC4 ZNF407 RAD54L2 MORC2 ARID1A XAB2 BLM UBR5 USP7 MACF1 RPRD2 SCFD1 DIAPH3 CLSPN KDM6A	1.27e-04	1370	90	21	MP:0001672
MousePheno	embryonic lethality before implantation	RGPD8 RGPD1 PSMC4 ZNF407 XAB2 SF3B1 UBR3 ATP2B1	1.64e-04	242	90	8	MP:0006204
Domain	ZnF_UBR1	UBR4 UBR5 UBR3	7.42e-06	7	113	3	SM00396
Domain	ZF_UBR	UBR4 UBR5 UBR3	7.42e-06	7	113	3	PS51157
Domain	zf-UBR	UBR4 UBR5 UBR3	7.42e-06	7	113	3	PF02207
Domain	Znf_UBR	UBR4 UBR5 UBR3	7.42e-06	7	113	3	IPR003126
Domain	Grip	RGPD8 RGPD1 RGPD5	3.43e-05	11	113	3	SM00755
Domain	GRIP	RGPD8 RGPD1 RGPD5	3.43e-05	11	113	3	PF01465
Domain	Ran_BP1	RGPD8 RGPD1 RGPD5	4.56e-05	12	113	3	PF00638
Domain	RANBD1	RGPD8 RGPD1 RGPD5	4.56e-05	12	113	3	PS50196
Domain	GRIP_dom	RGPD8 RGPD1 RGPD5	4.56e-05	12	113	3	IPR000237
Domain	GRIP	RGPD8 RGPD1 RGPD5	4.56e-05	12	113	3	PS50913
Domain	RanBD	RGPD8 RGPD1 RGPD5	5.90e-05	13	113	3	SM00160
Domain	Ran_bind_dom	RGPD8 RGPD1 RGPD5	5.90e-05	13	113	3	IPR000156
Domain	PXA	SNX13 SNX25	2.16e-04	4	113	2	SM00313
Domain	LRRC37AB_C	LRRC37A2 LRRC37A	2.16e-04	4	113	2	IPR029423
Domain	PXA	SNX13 SNX25	2.16e-04	4	113	2	PS51207
Domain	PXA	SNX13 SNX25	2.16e-04	4	113	2	PF02194
Domain	LRRC37AB_C	LRRC37A2 LRRC37A	2.16e-04	4	113	2	PF14914
Domain	Sorting_nexin_C	SNX13 SNX25	2.16e-04	4	113	2	IPR013937
Domain	LRRC37_N	LRRC37A2 LRRC37A	2.16e-04	4	113	2	IPR032754
Domain	LRRC37	LRRC37A2 LRRC37A	2.16e-04	4	113	2	PF15779
Domain	Phox_assoc	SNX13 SNX25	2.16e-04	4	113	2	IPR003114
Domain	Nexin_C	SNX13 SNX25	2.16e-04	4	113	2	PF08628
Domain	LRRC37A/B-like	LRRC37A2 LRRC37A	2.16e-04	4	113	2	IPR015753
Domain	TPR_1	RGPD8 RGPD1 TTC6 KDM6A RGPD5	2.16e-04	90	113	5	IPR001440
Domain	TPR_1	RGPD8 RGPD1 TTC6 KDM6A RGPD5	2.16e-04	90	113	5	PF00515
Domain	TPR-contain_dom	RGPD8 RGPD1 XAB2 TTC6 KDM6A RGPD5	3.03e-04	150	113	6	IPR013026
Domain	EXOC3/Sec6	EXOC3 EXOC3L1	3.59e-04	5	113	2	IPR010326
Domain	Sec6	EXOC3 EXOC3L1	3.59e-04	5	113	2	PF06046
Domain	Rab_bind	RGPD8 RGPD1	7.47e-04	7	113	2	PF16704
Domain	SLC12A_fam	SLC12A1 SLC12A7	7.47e-04	7	113	2	IPR004842
Domain	GCC2_Rab_bind	RGPD8 RGPD1	7.47e-04	7	113	2	IPR032023
Domain	SLC12_C	SLC12A1 SLC12A7	9.92e-04	8	113	2	IPR018491
Domain	SLC12	SLC12A1 SLC12A7	9.92e-04	8	113	2	PF03522
Domain	TPR	RGPD8 RGPD1 XAB2 TTC6 KDM6A	1.13e-03	129	113	5	SM00028
Domain	-	RGPD8 RGPD1	1.58e-03	10	113	2	1.10.220.60
Domain	RGS	MYH9 SNX13 SNX25	1.68e-03	39	113	3	IPR016137
Pathway	WP_KLEEFSTRA_SYNDROME	ACTL6A ARID1A KMT2C KDM6A	2.37e-05	29	83	4	M48076
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	VAPA CACNA1C MYH9 RGPD8 KDM5A SYNE1 UBR4 DPPA2 RGPD1 RAD54L2 ARID1A SF3B1 STARD9 SNX25 PLXNA4 MACF1 CCAR2 DIAPH3 POLQ DNAH6 ATP2B1 MED13 PRRC2B ZNF292 NSMCE4A RGPD5	1.43e-12	1442	116	26	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 SETD1B SYNE1 CAMTA2 SNX13 UBR5 STARD9 PDE4DIP PLCL2 MACF1 CCAR2 PPIP5K1 DISP2 PRRC2B SEZ6L	7.69e-12	407	116	15	12693553
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOA2 USP34 SETD1B RGPD8 PSMC4 EXOC3 RAD54L2 ARID1A BLM UBR5 USP7 MACF1 DIAPH3 CRYBG3 CLSPN SLX4 PRRC2B	1.30e-11	588	116	17	38580884
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	NCOA2 SYNE1 UBR4 FBXO30 AKAP12 KMT2C SF3B1 XIRP2 STARD9 PDE4DIP PRICKLE2 ZNF292	2.29e-11	233	116	12	37704626
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NCOA2 USP34 KDM5A SYNE1 UBR4 HECTD4 APBA1 RAD54L2 ARID1A XAB2 SF3B1 SCG2 PDE4DIP USP7 MACF1 TLN2 REPS2 KDM6A SLX4 MED13 SEZ6L ZNF292	2.59e-10	1285	116	22	35914814
Pubmed	Human transcription factor protein interaction networks.	VAPA NCOA2 CUL2 KDM5A RBMS1 KCMF1 UBR4 RGPD1 PSMC4 ACTL6A RAD54L2 MORC2 ARID1A BLM KMT2C USP7 CCAR2 ELF2 RPRD2 KDM6A SLX4 PRRC2B FILIP1L	3.18e-10	1429	116	23	35140242
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	USP34 PSMC4 RAD54L2 ARID1A BLM SF3B1 TRMT2A UBR5 ETAA1 RPRD2 MED7 ATP2B1 SLX4 MED13	4.01e-10	453	116	14	29656893
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 MYH9 RGPD8 KDM5A SYNE1 UBR4 KSR2 HECTD4 RGPD1 AKAP12 SF3B1 UBR5 PDE4DIP MACF1 CCAR2 TLN2 UNC79 PRRC2B TP53BP2	4.92e-10	963	116	19	28671696
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	MYH9 SETD1B KDM5A RBMS1 KCMF1 UBR4 PABPC4L KATNA1 MORC2 XAB2 KMT2C SLC12A1 TRMT2A UBR5 USP7 ELF2 DIAPH3 STRA6 CLSPN MED13 ZNF292	2.83e-09	1327	116	21	32694731
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	VAPA RGPD8 SYNE1 RGPD1 EXOC3 ACTL6A ARID1A FBXO30 XAB2 AKAP12 BLM SF3B1 UBR5 CCAR2 TLN2 SLX4 PRRC2B NSMCE4A RGPD5	9.53e-09	1155	116	19	20360068
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA2 ACTL6A ARID1A XAB2 USP7 ELF2 RPRD2 KDM6A MED13 PRRC2B	2.49e-08	268	116	10	33640491
Pubmed	Interaction network of human early embryonic transcription factors.	NCOA2 KDM5A RGPD1 ACTL6A RAD54L2 ARID1A KMT2C ELF2 KDM6A SLX4 PRRC2B	2.89e-08	351	116	11	38297188
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP34 SYNE1 RAD54L2 SNX13 SIK2 MACF1 FAM131B	5.08e-08	101	116	7	9872452
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	SETD1B ACTL6A ARID1A KMT2C SF3B1 KDM6A	5.78e-08	61	116	6	20305087
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CACNA1C KCMF1 PSMC4 EXOC3 ACTL6A MORC2 TTC6 BLM KMT2C XIRP2 USP7 ZNF292	1.14e-07	497	116	12	36774506
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 FRAS1 SETD1B UBR4 KSR2 HECTD4 PANX1 FRYL CFAP43 ARID1A KMT2C USP7 TLN2 DISP2 MED13 PRRC2B AHNAK2	1.61e-07	1105	116	17	35748872
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	VAPA MYH9 PSMC4 ACTL6A ARID1A SF3B1 PALLD AHNAK2 FILIP1L	2.34e-07	259	116	9	31162944
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	VAPA MYH9 RGPD8 UBR4 RGPD1 APBA1 PSMC4 SF3B1 SNX25 PDE4DIP PRICKLE2 USP7 UBR3 MACF1 TLN2 CRYBG3 FAM131B	2.47e-07	1139	116	17	36417873
Pubmed	Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.	KCMF1 UBR4 PSMC4 UBR5 USP7 UBR3	2.75e-07	79	116	6	27325702
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL2 FRAS1 EXOC3 RAD54L2 MORC2 XAB2 TRMT2A SIK2 CRYBG3 CLSPN SLC12A7 PALLD PRRC2B	2.85e-07	650	116	13	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 MYH9 UBR4 FRYL ARID1A XAB2 BLM SF3B1 UBR5 USP7 MACF1 CCAR2 PRRC2B	3.00e-07	653	116	13	22586326
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	NCOA2 MYH9 RAD54L2 XAB2 BLM SF3B1 USP7 ELF2 PALLD SLX4 AHNAK2	3.07e-07	444	116	11	34795231
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA2 ACTL6A ARID1A KMT2C USP7 RPRD2 DIAPH3 KDM6A PALLD PRRC2B TP53BP2 RGPD5	3.30e-07	549	116	12	38280479
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	UBR4 CDH23 KATNA1 CYP46A1 SF3B1 MACF1 TLN2 DNAH6 PALLD PRRC2B	3.95e-07	361	116	10	26167880
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 KCMF1 UBR4 ARID1A UBR5 USP7 MACF1 CCAR2 SCFD1	4.77e-07	282	116	9	23667531
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYH9 SETD1B UBR4 PSMC4 EXOC3 ACTL6A ARID1A BLM SF3B1 UBR5 USP7 MACF1 CCAR2 SCFD1 ATP2B1 PALLD TP53BP2 AHNAK2	5.65e-07	1353	116	18	29467282
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	SETD1B PSMC4 KMT2C UBR5 KDM6A	7.11e-07	50	116	5	37974198
Pubmed	Functional proteomics mapping of a human signaling pathway.	UBR4 XAB2 SF3B1 ZFYVE9 UBR5 PDE4DIP PHACTR3 PLCL2 MACF1 DIAPH3 KDM6A TP53BP2	7.17e-07	591	116	12	15231748
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	NCOA2 USP34 ACTL6A ARID1A KMT2C SF3B1 USP7 KDM6A	7.98e-07	220	116	8	35785414
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	RGPD8 UBR4 RGPD1 ACTL6A ARID1A AKAP12 UBR5	8.67e-07	153	116	7	26365490
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 SYNE1 KMT2C UBR5 SIK2 MACF1 TLN2 RPRD2	9.45e-07	225	116	8	12168954
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD8 RGPD1 RGPD5	1.25e-06	7	116	3	15710750
Pubmed	New nomenclature for chromatin-modifying enzymes.	NCOA2 SETD1B KDM5A KMT2C KDM6A	1.38e-06	57	116	5	18022353
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 MYH9 RGPD8 KDM5A UBR4 RGPD1 UBR5 DIAPH3 CRYBG3 TP53BP2	1.48e-06	418	116	10	34709266
Pubmed	Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.	ARID1A KMT2C CCAR2 MED13 AHNAK2	1.64e-06	59	116	5	28813667
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	UBR4 PSMC4 RAD54L2 XAB2 SF3B1 USP7 CCAR2 PALLD AHNAK2	1.84e-06	332	116	9	32786267
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PSMC4 EXOC3 ARID1A BLM ZFYVE9 PLCL2 USP7 UBR3 CCAR2 CRYBG3 SLC12A7 ATP2B1 KDM6A PRRC2B TP53BP2	2.26e-06	1049	116	15	27880917
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	VAPA CUL2 MYH9 UBR4 PSMC4 FRYL ACTL6A ARID1A SLC2A3 XAB2 AKAP12 SF3B1 SCP2 SCFD1 PALLD PRRC2B AHNAK2	2.99e-06	1367	116	17	32687490
Pubmed	Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.	UBR4 UBR5 UBR3	2.99e-06	9	116	3	17855541
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SYNE1 APBA1 FRYL PDE4DIP MACF1 RGPD5	3.24e-06	120	116	6	31413325
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	XAB2 BLM SF3B1 UBR5 CCAR2 RPRD2 CLSPN SLX4 PRRC2B	3.32e-06	357	116	9	37059091
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	EXOC3 ARID1A FBXO30 BLM USP7 MACF1 TLN2 RPRD2 CRYBG3 TP53BP2	4.36e-06	472	116	10	38943005
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPM6B MYH9 SYNE1 ARID1A SLC2A3 ERMN SF3B1 PDE4DIP PLXNA4 PRICKLE2 USP7 MACF1 TLN2 DNAH6 ATP2B1 PRRC2B TP53BP2	5.48e-06	1431	116	17	37142655
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	KDM5A RBMS1 MORC2 XAB2 AKAP12 MACF1 DIAPH3 PALLD PRRC2B AHNAK2 ZNF292 NSMCE4A	5.78e-06	724	116	12	36232890
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	ACTL6A ARID1A XAB2 USP7 CCAR2 RPRD2	6.13e-06	134	116	6	25452129
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	MYH9 SETD1B PSMC4 ACTL6A FBXO30 KMT2C SAMD13 USP7 KDM6A ZNF292	6.61e-06	495	116	10	27705803
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	VAPA CUL2 MYH9 UBR4 PSMC4 SLC2A3 XAB2 AKAP12 SF3B1 UBR5 MACF1 CCAR2 C3 DIAPH3 PALLD PRRC2B	6.65e-06	1297	116	16	33545068
Pubmed	HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.	UBR4 UBR5 UBR3	7.78e-06	12	116	3	17360488
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA2 ARID1A ELF2 KDM6A ZNF292	8.93e-06	83	116	5	28794006
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	VAPA CUL2 FRAS1 SYNE1 UBR4 PSMC4 EXOC3 AKAP12 BLM SF3B1 UBR5 SIK2 MACF1 SCFD1 DIAPH3 CRYBG3 ATP2B1	9.05e-06	1487	116	17	33957083
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	ACTL6A ARID1A USP7 KDM6A	9.79e-06	40	116	4	34585037
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA2 ATP13A4 UBR4 RGPD1 ARID1A C17orf75 PHACTR3 ATP2B1 KDM6A PRRC2B AHNAK2	1.00e-05	638	116	11	31182584
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	NCOA2 MYH9 MORC2 SF3B1 UBR5	1.00e-05	85	116	5	16051665
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ACTL6A RAD54L2 MORC2 BLM RPRD2 POLQ SLX4	1.02e-05	222	116	7	37071664
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 EXOC3 FRYL BLM UBR5 USP7	1.04e-05	147	116	6	29576527
Pubmed	Splicing factor SF3B1 promotes endometrial cancer progression via regulating KSR2 RNA maturation.	KSR2 SF3B1	1.10e-05	2	116	2	33040078
Pubmed	BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres.	BLM SLX4	1.10e-05	2	116	2	28877996
Pubmed	USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin.	USP7 CLSPN	1.10e-05	2	116	2	19124652
Pubmed	A puzzle over several decades: eye anomalies with FRAS1 and STRA6 mutations in the same family.	FRAS1 STRA6	1.10e-05	2	116	2	22283518
Pubmed	Association of CACNA1C and SYNE1 in offspring of patients with psychiatric disorders.	CACNA1C SYNE1	1.10e-05	2	116	2	27620326
Pubmed	Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics.	NCOA2 STRA6	1.10e-05	2	116	2	30325183
Pubmed	Talin2 binds to non-muscle myosin IIa and regulates cell attachment and fibronectin secretion.	MYH9 TLN2	1.10e-05	2	116	2	39215026
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	VAPA MYH9 UBR4 RGPD1 PSMC4 AKAP12 UBR5 UBR3 CCAR2 C3 ATP2B1	1.14e-05	647	116	11	26618866
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	FRAS1 SYNE1 CDH23 BLM PDE4DIP MACF1	1.26e-05	152	116	6	34299191
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MYH9 RGPD8 RGPD1 PRICKLE2 MACF1 FAM131B PRRC2B	1.31e-05	231	116	7	16452087
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	RGPD8 SYNE1 SF3B1 SNX25 USP7 MACF1 PPIP5K1	1.43e-05	234	116	7	36243803
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	VAPA RGPD8 UBR4 RGPD1 PSMC4 ACTL6A ARID1A AKAP12 TRMT2A CCAR2 SCFD1	1.47e-05	665	116	11	30457570
Pubmed	Congenital Diaphragmatic Hernia Overview	FRAS1 ARID1A STRA6 KDM6A	1.72e-05	46	116	4	20301533
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	ACTL6A XAB2 BLM USP7 CCAR2 ELF2 RPRD2 CLSPN	1.91e-05	339	116	8	30415952
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NCOA2 PSMC4 ACTL6A RAD54L2 MORC2 ARID1A KMT2C UBR5 SCP2 CCAR2 ELF2 KDM6A PRRC2B ZNF292	1.92e-05	1103	116	14	34189442
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	SETD1B KMT2C KDM6A	1.96e-05	16	116	3	24368734
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FRYL CAMTA2 MORC2 UBR5 SCFD1	2.21e-05	100	116	5	10048485
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	VAPA MYH9 RGPD8 SYNE1 UBR4 RGPD1 SF3B1 PHACTR3 MACF1 SCFD1 PALLD RGPD5	2.64e-05	844	116	12	25963833
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	USP34 LRRC37A MED13 PRRC2B ZNF292	2.80e-05	105	116	5	9628581
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	BLM KMT2C KDM6A	2.84e-05	18	116	3	17500065
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NCOA2 KDM5A UBR4 ACTL6A MORC2 BLM ZBTB37 SF3B1 TRMT2A UBR5 CCAR2 ATP2B1	3.07e-05	857	116	12	25609649
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KDM5A FRYL STARD9 SIK2 MACF1 CRYBG3 TSSK1B ATP2B1 PALLD TP53BP2 MAP3K2 AHNAK2	3.21e-05	861	116	12	36931259
Pubmed	UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.	UBR4 UBR5	3.30e-05	3	116	2	32558906
Pubmed	Stress response silencing by an E3 ligase mutated in neurodegeneration.	KCMF1 UBR4	3.30e-05	3	116	2	38297121
Pubmed	Uncommon somatic mutations in metastatic NUT midline carcinoma.	KMT2C SF3B1	3.30e-05	3	116	2	28967088
Pubmed	Histone lysine demethylases in breast cancer.	KDM5A KDM6A	3.30e-05	3	116	2	23266085
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	VAPA CUL2 RBMS1 PSMC4 EXOC3 CDH23 FBXO30 AKAP12 BLM PLCL2 CCAR2 C3 PRRC2B TP53BP2 MAP3K2	3.46e-05	1321	116	15	27173435
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	CUL2 MYH9 KCMF1 UBR4 PSMC4 PALLD	3.48e-05	182	116	6	31067453
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CUL2 USP34 MYH9 UBR4 MORC2 XAB2 BLM SF3B1 UBR5 USP7 CCAR2 KDM6A MED13	3.51e-05	1014	116	13	32416067
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CUL2 UBR4 HECTD4 PSMC4 ZFYVE9 UBR5 MACF1 PALLD SLX4	3.54e-05	481	116	9	28190767
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	CUL2 KCMF1 UBR4 ACTL6A MORC2 FBXO30 TRMT2A UBR5 USP7 TP53BP2	3.64e-05	604	116	10	38803224
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	UBR4 PDE4DIP MACF1 RPRD2	3.77e-05	56	116	4	9455484
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 XIRP2 MACF1	3.95e-05	20	116	3	21689717
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1B KMT2C KDM6A	3.95e-05	20	116	3	29785026
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	CUL2 MYH9 PSMC4 AKAP12 BLM SF3B1 USP7 CCAR2 PALLD	4.35e-05	494	116	9	26831064
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	BLM UBR5 USP7 CLSPN PRRC2B	4.52e-05	116	116	5	30804394
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KDM5A SYNE1 ZNF407 AKAP12 XIRP2 PDE4DIP MACF1 PALLD MED13	4.56e-05	497	116	9	23414517
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM5A KMT2C KDM6A	4.60e-05	21	116	3	27626377
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CUL2 MYH9 RBMS1 PSMC4 TRMT2A UBR5 PDE4DIP USP7 SCFD1 ATP2B1 PRRC2B	4.62e-05	754	116	11	33060197
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	SETD1B PSMC4 ARID1A XAB2 SF3B1 MED7 ZNF292	4.80e-05	283	116	7	18854154
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	SETD1B BLM KMT2C UBR5 KDM6A	5.11e-05	119	116	5	23508102
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MYH9 PSMC4 ACTL6A ARID1A FBXO30 XAB2 SF3B1 USP7 RPRD2	5.24e-05	506	116	9	30890647
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	SETD1B KMT2C KDM6A	5.32e-05	22	116	3	26886794
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM5A MORC2 BLM SF3B1 USP7 CCAR2 TLN2 ELF2 SCFD1 KDM6A MED13	5.84e-05	774	116	11	15302935
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ARID1A CCAR2 ELF2 AHNAK2 ZNF292	5.98e-05	123	116	5	26912792
Interaction	AR interactions	NCOA2 CUL2 USP34 HECTD4 PSMC4 ACTL6A RAD54L2 ARID1A STAP1 XAB2 KMT2C SF3B1 UBR5 USP7 CCAR2 ELF2 RPRD2 REPS2 KDM6A MED13 PRRC2B	1.53e-07	992	114	21	int:AR
Interaction	ERG interactions	NCOA2 UBR4 RAD54L2 ARID1A KMT2C SF3B1 UBR5 KDM6A SLX4 PRRC2B	5.61e-07	223	114	10	int:ERG
Interaction	NUP43 interactions	USP34 SETD1B RGPD8 KDM5A RAD54L2 MORC2 ARID1A BLM UBR5 CCAR2 ELF2 SLX4 AHNAK2 ZNF292 RGPD5	2.44e-06	625	114	15	int:NUP43
Interaction	CST9 interactions	PCP2 KCMF1 UBR4	3.48e-06	6	114	3	int:CST9
Interaction	HNF4A interactions	NCOA2 RAD54L2 MORC2 ARID1A BLM KMT2C ELF2 MED7 KDM6A SLX4	3.72e-06	275	114	10	int:HNF4A
Interaction	BUB3 interactions	CUL2 SETD1B KCMF1 EXOC3 KMT2C UBR5 USP7 KDM6A SLX4	6.91e-06	232	114	9	int:BUB3
Interaction	EGLN3 interactions	VAPA NCOA2 USP34 KCMF1 UBR4 APBA1 PSMC4 RAD54L2 FBXO30 BLM C17orf75 ZFYVE9 UBR5 ETAA1 USP7 SIK2 SCFD1 DIAPH3 CLSPN SLX4 PRRC2B	1.09e-05	1296	114	21	int:EGLN3
Interaction	MTNR1B interactions	USP34 GPM6B UBR4 SLC2A3 KMT2C MACF1 RPRD2	1.17e-05	135	114	7	int:MTNR1B
Interaction	SIRT6 interactions	SETD1B RGPD8 HECTD4 ACTL6A ARID1A BLM UBR5 USP7 CCAR2 RPRD2 PALLD SLX4 NSMCE4A RGPD5	1.25e-05	628	114	14	int:SIRT6
Interaction	RGPD2 interactions	RGPD8 RGPD1 EXOC3 RGPD5	1.54e-05	27	114	4	int:RGPD2
Interaction	TPRX2 interactions	NCOA2 ACTL6A ARID1A ELF2 KDM6A	1.61e-05	56	114	5	int:TPRX2
Interaction	SOX9 interactions	CUL2 RGPD1 ARID1A KMT2C USP7 KDM6A	1.87e-05	97	114	6	int:SOX9
Interaction	SLX4 interactions	ACTL6A RAD54L2 MORC2 XAB2 BLM SF3B1 UBR5 CCAR2 RPRD2 CLSPN POLQ SLX4 PRRC2B	2.13e-05	572	114	13	int:SLX4
Interaction	WWTR1 interactions	NCOA2 ACTL6A ARID1A USP7 RPRD2 DIAPH3 KDM6A PRRC2B TP53BP2 MAP3K2 RGPD5	2.77e-05	422	114	11	int:WWTR1
Interaction	SEM1 interactions	CUL2 UBR4 PSMC4 UBR5 USP7 TLN2 DNAH6	3.81e-05	162	114	7	int:SEM1
Interaction	SOX2 interactions	NCOA2 USP34 RBMS1 KCMF1 UBR4 KSR2 PABPC4L ACTL6A ARID1A KMT2C UBR5 PRICKLE2 USP7 MACF1 CCAR2 ELF2 C3 SCFD1 KDM6A PRRC2B ZNF292	4.31e-05	1422	114	21	int:SOX2
Interaction	UBC interactions	CUL2 USP34 MYH9 UBR4 HECTD4 PSMC4 ZFYVE9 UBR5 USP7 PALLD SLX4	4.58e-05	446	114	11	int:UBC
Interaction	TP53BP1 interactions	USP34 PSMC4 RAD54L2 ARID1A BLM SF3B1 TRMT2A UBR5 POLQ MED7 SLX4 MED13	4.94e-05	533	114	12	int:TP53BP1
Interaction	EGR2 interactions	NCOA2 RAD54L2 ARID1A KMT2C PDE4DIP KDM6A PRRC2B	5.38e-05	171	114	7	int:EGR2
Interaction	FBXO22 interactions	CACNA1C KCMF1 PSMC4 EXOC3 ACTL6A MORC2 TTC6 BLM KMT2C XIRP2 USP7 ZNF292	5.60e-05	540	114	12	int:FBXO22
Interaction	ANPEP interactions	VAPA UBR4 PANX1 AKAP12 ZFYVE9 SIK2 AHNAK2	6.00e-05	174	114	7	int:ANPEP
Interaction	CEP83 interactions	VAPA MYH9 USP7 PALLD	6.86e-05	39	114	4	int:CEP83
Interaction	TOP3B interactions	CUL2 USP34 FRAS1 SETD1B RBMS1 KCMF1 UBR4 KSR2 HECTD4 APBA1 PANX1 FRYL CFAP43 ARID1A KMT2C USP7 TLN2 DISP2 MED13 PRRC2B AHNAK2	6.96e-05	1470	114	21	int:TOP3B
Interaction	HIF1AN interactions	VAPA PSMC4 BLM PLXNA4 USP7 CCAR2 TLN2 RPRD2 TP53BP2	8.03e-05	317	114	9	int:HIF1AN
Interaction	GOLGA1 interactions	UBR4 RGPD1 MACF1 DIAPH3 CRYBG3 TP53BP2 AHNAK2	8.24e-05	183	114	7	int:GOLGA1
Interaction	SOX7 interactions	NCOA2 ARID1A KMT2C KDM6A ZNF292	1.02e-04	82	114	5	int:SOX7
Interaction	KCNA3 interactions	VAPA NCOA2 MYH9 PSMC4 EXOC3 MORC2 AKAP12 KMT2C MACF1 TLN2 DIAPH3 CRYBG3 POLQ ATP2B1 PALLD	1.17e-04	871	114	15	int:KCNA3
Interaction	ESRRB interactions	VAPA NCOA2 KDM5A RAD54L2 ARID1A KMT2C MED7 MED13	1.23e-04	262	114	8	int:ESRRB
Interaction	SUMO2 interactions	UBR4 PSMC4 RAD54L2 XAB2 BLM SF3B1 USP7 CCAR2 PALLD SLX4 TP53BP2 AHNAK2	1.31e-04	591	114	12	int:SUMO2
Interaction	ASH2L interactions	SETD1B PSMC4 KMT2C UBR5 CCAR2 ELF2 KDM6A ZNF292	1.33e-04	265	114	8	int:ASH2L
Interaction	NPIPB6 interactions	RGPD8 RGPD1 RGPD5	1.35e-04	18	114	3	int:NPIPB6
Interaction	NUP50 interactions	RGPD8 MORC2 ARID1A XAB2 BLM RPRD2 CLSPN SLX4 ZNF292	1.40e-04	341	114	9	int:NUP50
Interaction	RGPD3 interactions	RGPD8 RGPD1 SLX4 RGPD5	1.44e-04	47	114	4	int:RGPD3
Interaction	NR1I3 interactions	NCOA2 PSMC4 SNX13 MED13	1.56e-04	48	114	4	int:NR1I3
Interaction	H3C1 interactions	MYH9 SETD1B KDM5A SYNE1 UBR4 MORC2 BLM KMT2C SF3B1 XIRP2 USP7 ELF2 KDM6A PALLD ZNF292	1.69e-04	901	114	15	int:H3C1
Interaction	TNRC6A interactions	RBMS1 ARID1A KMT2C UBR5 CCAR2 MED13 PRRC2B AHNAK2	1.94e-04	280	114	8	int:TNRC6A
Interaction	SOX17 interactions	NCOA2 ARID1A KMT2C CCAR2 KDM6A	2.05e-04	95	114	5	int:SOX17
Interaction	MIGA2 interactions	VAPA KCMF1 UBR4	2.18e-04	21	114	3	int:MIGA2
Interaction	RBBP5 interactions	SETD1B MORC2 ARID1A BLM KMT2C CCAR2 ELF2 KDM6A	2.29e-04	287	114	8	int:RBBP5
Interaction	CCDC92 interactions	RGPD8 PSMC4 TP53BP2 RGPD5	2.30e-04	53	114	4	int:CCDC92
Interaction	CAV1 interactions	VAPA EXOC3 PANX1 AKAP12 ZFYVE9 USP7 SCP2 MACF1 SCFD1 DIAPH3 SLC12A7 ATP2B1 AHNAK2	2.30e-04	724	114	13	int:CAV1
Interaction	STX6 interactions	EXOC3 AKAP12 ZFYVE9 MACF1 SCFD1 DIAPH3 CRYBG3 SLC12A7 ATP2B1 AHNAK2	2.31e-04	448	114	10	int:STX6
Interaction	KLF15 interactions	NCOA2 SNX13 BLM KMT2C CCAR2 KDM6A PRRC2B ZNF292	2.46e-04	290	114	8	int:KLF15
Interaction	RPA4 interactions	VAPA USP34 BLM SF3B1 STARD9 CCAR2 RPRD2 PALLD SLX4 TP53BP2	2.48e-04	452	114	10	int:RPA4
Interaction	RGPD4 interactions	RGPD8 RGPD1 RGPD5	2.51e-04	22	114	3	int:RGPD4
Interaction	SIRT7 interactions	USP34 MYH9 UBR4 FRYL ARID1A XAB2 BLM SF3B1 UBR5 USP7 MACF1 CCAR2 PRRC2B	2.99e-04	744	114	13	int:SIRT7
Interaction	SP7 interactions	NCOA2 ARID1A KMT2C ELF2 RPRD2 KDM6A PRRC2B FILIP1L	3.37e-04	304	114	8	int:SP7
Interaction	LHX4 interactions	NCOA2 ARID1A KMT2C ELF2 KDM6A TP53BP2	3.65e-04	166	114	6	int:LHX4
Interaction	FLOT1 interactions	VAPA MYH9 EXOC3 AKAP12 ZFYVE9 MACF1 ELF2 CRYBG3 SLC12A7 ATP2B1	3.68e-04	475	114	10	int:FLOT1
Interaction	C1orf115 interactions	KCMF1 UBR4 UBR5	3.70e-04	25	114	3	int:C1orf115
Interaction	MCM2 interactions	VAPA MYH9 RGPD8 SYNE1 UBR4 KSR2 RGPD1 ACTL6A SF3B1 UBR5 PHACTR3 MACF1 SCFD1 CLSPN PALLD RGPD5	3.82e-04	1081	114	16	int:MCM2
Interaction	MCRS1 interactions	SETD1B UBR4 ACTL6A BLM UBR5 ELF2 KDM6A	3.83e-04	235	114	7	int:MCRS1
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR4 UBR5 UBR3	2.88e-06	7	80	3	785
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD8 RGPD1 TTC6 KDM6A RGPD5	1.57e-04	115	80	5	769
GeneFamily	Solute carriers	SLC11A2 SLC22A7 SLC2A3 SLC12A1 SLC12A7 SLC30A10 SLC4A9	1.82e-03	395	80	7	752
GeneFamily	AT-rich interaction domain containing	KDM5A ARID1A	1.96e-03	15	80	2	418
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NCOA2 CUL2 USP34 SLC11A2 KDM5A RBMS1 FRYL SNX13 BLM ZFYVE9 UBR5 USP7 MACF1 CRYBG3 ATP2B1 MED13 TP53BP2 FILIP1L ZNF292	7.05e-09	856	116	19	M4500
Coexpression	GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP	AOX1 SLC22A7 SNX13 BLM SF3B1 MACF1 ATP2B1 PALLD SEZ6L	2.43e-07	197	116	9	M9569
Coexpression	GABRIELY_MIR21_TARGETS	USP34 SNX13 UBR5 PRICKLE2 USP7 UBR3 PALLD MAP3K2 FILIP1L ZNF292	6.63e-07	289	116	10	M2196
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	KDM5A RBMS1 FRYL SNX13 BLM ZFYVE9 UBR5 ATP2B1 MED13 TP53BP2 FILIP1L ZNF292	1.12e-06	466	116	12	M13522
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	CACNA1C KSR2 MDGA2 TMEM196 SCG2 PDE4DIP PHACTR3 PLXNA4 PRICKLE2 TLN2 ATP2B1 UNC79 FAM131B ZNF292	2.85e-06	703	116	14	M39070
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	USP34 MYH9 KDM5A RBMS1 SYNE1 KCMF1 UBR4 HECTD4 FRYL ARID1A SLC2A3 KMT2C SF3B1 UBR5 PDE4DIP MACF1 MED13 PRRC2B MAP3K2 ZNF292	8.33e-06	1492	116	20	M40023
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOMTN	CACNA1C MDGA2 C17orf75 PHACTR3 PLXNA4 TLN2 ATP2B1 UNC79 FAM131B AHNAK2	9.32e-06	389	116	10	M39073
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	CACNA1C KSR2 APBA1 MDGA2 TMEM196 PDE4DIP PHACTR3 PLXNA4 PRICKLE2 TLN2 ATP2B1 UNC79 PRRC2B SEZ6L MAP3K2 AHNAK2	2.99e-05	1106	116	16	M39071
Coexpression	GSE13306_TREG_RA_VS_TCONV_RA_DN	GPM6B RAD54L2 KMT2C PPIP5K1 MED7 SLC12A7 PALLD	3.13e-05	200	116	7	M3227
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CUL2 GPM6B EXOC3 ZNF407 SNX13 BLM ETAA1 SCP2 DIAPH3 POLQ PALLD MAP3K2	3.51e-05	656	116	12	M18979
Coexpression	LAKE_ADULT_KIDNEY_C28_INTERSTITIUM	CACNA1C RBMS1 SYNE1 AKAP12 PALLD	4.07e-05	86	116	5	M39247
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	CUL2 RGPD8 FRYL SNX13 ERMN SF3B1 ATP2B1 KDM6A MED13 MAP3K2 ZNF292 RGPD5	4.96e-05	680	116	12	M41089
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	CACNA1C KSR2 APBA1 TMEM196 SCG2 PDE4DIP PHACTR3 PLXNA4 PRICKLE2 UNC79 SEZ6L	5.82e-05	584	116	11	M39068
Coexpression	GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN	VAPA STAP1 XAB2 TRMT2A TSSK1B SEZ6L	7.76e-05	159	116	6	M6086
Coexpression	CUI_TCF21_TARGETS_2_DN	RBMS1 FRYL SLC2A3 SNX13 KMT2C SLC12A1 PDE4DIP UBR3 MACF1 KDM6A PALLD MED13 MAP3K2	1.06e-04	854	116	13	M1533
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	MYH9 RBMS1 SYNE1 AKAP12 UBR3 PALLD	1.40e-04	177	116	6	M39245
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	FRYL ARID1A ZBTB37 KMT2C MACF1 MED13	1.53e-04	180	116	6	M8239
Coexpression	CUI_TCF21_TARGETS_2_DN	RBMS1 FRYL SLC2A3 SNX13 KMT2C SLC12A1 PDE4DIP UBR3 MACF1 KDM6A PALLD MED13 MAP3K2	1.56e-04	888	116	13	MM1018
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	SYNE1 SF3B1 UBR5 MACF1 SLC12A7 MAP3K2	1.73e-04	184	116	6	M9005
Coexpression	LU_AGING_BRAIN_UP	FRYL ACTL6A UBR5 PDE4DIP SCP2 PALLD TP53BP2	1.74e-04	263	116	7	M5547
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	USP34 UBR4 LRRC37A2 TMEM196 USP7 MACF1	2.00e-04	189	116	6	M3112
Coexpression	ONKEN_UVEAL_MELANOMA_UP	NCOA2 GPM6B SLC11A2 RBMS1 MORC2 SLC2A3 UBR5 PDE4DIP MACF1 MED7 ATP2B1 AHNAK2	2.03e-04	790	116	12	M12490
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	USP34 LRRC37A2 UBR5 PLCL2 POLQ PALLD	2.30e-04	194	116	6	M7467
Coexpression	GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN	SLC11A2 SLC2A3 PDE4DIP PLCL2 ATP2B1 NSMCE4A	2.57e-04	198	116	6	M8173
Coexpression	GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN	USP34 SETD1B SF3B1 USP7 UBR3 TLN2	2.57e-04	198	116	6	M3552
Coexpression	GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN	AKAP12 PLCL2 USP7 ELF2 ATP2B1 FILIP1L	2.57e-04	198	116	6	M5701
Coexpression	GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN	CAMTA2 KMT2C SCP2 PRRC2B FILIP1L ZNF292	2.64e-04	199	116	6	M9443
Coexpression	GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP	AOX1 PSMC4 FRYL AKAP12 TLN2 PALLD	2.64e-04	199	116	6	M7766
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP	RBMS1 PSMC4 SLC2A3 PDE4DIP MACF1 TP53BP2	2.64e-04	199	116	6	M7656
Coexpression	GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN	SLC11A2 PANX1 C17orf75 PALLD MED13 TP53BP2	2.64e-04	199	116	6	M8352
Coexpression	GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	MYH9 SETD1B FRYL PLCL2 USP7 ELF2	2.64e-04	199	116	6	M5357
Coexpression	CAMP_UP.V1_DN	SLC2A3 AKAP12 TLN2 ATP2B1 UNC79 PALLD	2.64e-04	199	116	6	M2719
Coexpression	GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	NCOA2 RBMS1 MDGA2 PLCL2 CLSPN MED7	2.64e-04	199	116	6	M3070
Coexpression	DITTMER_PTHLH_TARGETS_DN	MYH9 AOX1 PANX1 SNX13	2.67e-04	70	116	4	M18667
Coexpression	GSE3039_CD4_TCELL_VS_NKT_CELL_UP	NCOA2 SYNE1 CAMTA2 ARID1A PRICKLE2 NSMCE4A	2.71e-04	200	116	6	M6426
Coexpression	GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN	USP34 MYH9 SETD1B RBMS1 SYNE1 ATP2B1	2.71e-04	200	116	6	M8331
Coexpression	GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_DN	SETD1B PANX1 SLC2A3 STAP1 TRMT2A UBR5	2.71e-04	200	116	6	M8558
Coexpression	GSE3982_MAST_CELL_VS_TH2_DN	CACNA1C FRYL XAB2 BLM ETAA1 CRYBG3	2.71e-04	200	116	6	M5456
Coexpression	GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_UP	MYH9 UBR4 XAB2 KMT2C RPRD2 SLC12A7	2.71e-04	200	116	6	M7207
Coexpression	GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN	MYH9 SETD1B ARID1A SLC2A3 UBR5 CCAR2	2.71e-04	200	116	6	M7423
Coexpression	WALLACE_PROSTATE_CANCER_DN	GPM6B AKAP12	2.88e-04	6	116	2	M12533
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	CAMTA2 SLC2A3 PDE4DIP SLC12A7 ATP2B1 KDM6A PALLD PRRC2B TP53BP2 MAP3K2 AHNAK2 RGPD5	2.91e-04	822	116	12	M6782
Coexpression	ENK_UV_RESPONSE_KERATINOCYTE_DN	SLC11A2 KDM5A ACTL6A SLC2A3 UBR5 USP7 MACF1 SCFD1 MED7	2.95e-04	481	116	9	M3898
Coexpression	BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP	RAD54L2 MACF1 TLN2 CRYBG3 MED13	3.65e-04	137	116	5	M34024
Coexpression	LAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES	CACNA1C RBMS1 SYNE1 AKAP12 MACF1	3.65e-04	137	116	5	M39241
Coexpression	ZHONG_PFC_C6_PLXNA4_POS_EXCITATORY_NEURON	SCG2 PLXNA4	4.02e-04	7	116	2	M39090
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000	KSR2 APBA1 SLC2A3 AKAP12 PLXNA4 TLN2 DISP2 UNC79	1.98e-05	211	115	8	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000	VAPA MYH9 KDM5A SNX13 SLC12A1 UBR3 ELF2 MED7 MED13 ZNF292	3.77e-05	375	115	10	gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 FRAS1 SYNE1 FRYL AKAP12 ZBTB37 KMT2C MACF1 ZNF292	2.51e-09	197	116	9	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 ZNF407 KMT2C MACF1 KDM6A MED13 TP53BP2 MAP3K2	3.46e-08	188	116	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C GPM6B AOX1 CDH23 PDE4DIP PHACTR3 TLN2 PALLD	4.41e-08	194	116	8	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE1 ZNF407 FRYL ZBTB37 MACF1 ZNF292 RGPD5	5.37e-08	199	116	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 FRAS1 MDGA2 XIRP2 PHACTR3 TLN2 UNC79	5.47e-07	184	116	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 FRAS1 MDGA2 XIRP2 PHACTR3 TLN2 UNC79	5.47e-07	184	116	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 FRAS1 MDGA2 XIRP2 PHACTR3 TLN2 UNC79	5.47e-07	184	116	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C GPM6B FRAS1 AOX1 PHACTR3 MACF1 PALLD	7.02e-07	191	116	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRAS1 SYNE1 FRYL AKAP12 ZBTB37 MACF1 ZNF292	7.53e-07	193	116	7	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 KDM5A RBMS1 UBR5 KDM6A MED13 ZNF292	7.53e-07	193	116	7	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 USP34 ZNF407 KMT2C UBR5 UBR3 KDM6A	9.24e-07	199	116	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 APBA1 AKAP12 TMEM196 PHACTR3 C3	3.68e-06	158	116	6	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 APBA1 AKAP12 TMEM196 PHACTR3 C3	3.68e-06	158	116	6	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	BAL-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	SLC2A3 LRRC37A DISP2 CLSPN SLC12A7 RGPD5	4.10e-06	161	116	6	7a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	SYNE1 APBA1 AKAP12 TMEM196 PHACTR3 C3	5.99e-06	172	116	6	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	USP34 SLC2A3 UBR5 MACF1 KDM6A MAP3K2	8.02e-06	181	116	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A3 AKAP12 PHACTR3 MACF1 C3 KDM6A	8.81e-06	184	116	6	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 APBA1 MDGA2 AKAP12 PHACTR3 PALLD	9.09e-06	185	116	6	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 APBA1 MDGA2 AKAP12 PHACTR3 PALLD	9.09e-06	185	116	6	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 HECTD4 ARID1A PRICKLE2 TLN2 MED13	9.37e-06	186	116	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 HECTD4 ARID1A PRICKLE2 TLN2 MED13	9.37e-06	186	116	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	CACNA1C GPM6B FRAS1 PHACTR3 MACF1 PALLD	9.66e-06	187	116	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6B RBMS1 SYNE1 MDGA2 AKAP12 STARD9	9.66e-06	187	116	6	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6B RBMS1 SYNE1 MDGA2 AKAP12 STARD9	9.66e-06	187	116	6	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6B RBMS1 SYNE1 MDGA2 AKAP12 STARD9	9.96e-06	188	116	6	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SLC11A2 KSR2 STAP1 PLCL2 SLC4A9	9.96e-06	188	116	6	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 UBR5 PRICKLE2 STRA6 UNC79 SEZ6L	9.96e-06	188	116	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	ERMN ATP2B1 KDM6A FILIP1L ZNF292 RGPD5	1.09e-05	191	116	6	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 KDM5A UBR5 KDM6A MED13 ZNF292	1.12e-05	192	116	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C FRAS1 AOX1 PHACTR3 MACF1 PALLD	1.12e-05	192	116	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NCOA2 USP34 RGPD8 KMT2C SIK2 KDM6A	1.16e-05	193	116	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C GPM6B FRAS1 PHACTR3 PLXNA4 PALLD	1.23e-05	195	116	6	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRYL KMT2C SCG2 MACF1 ATP2B1 SEZ6L	1.23e-05	195	116	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRYL KMT2C SCG2 MACF1 ATP2B1 SEZ6L	1.23e-05	195	116	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C SYNE1 KSR2 MDGA2 ATP2B1 UNC79	1.26e-05	196	116	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	SYNE1 CFAP43 PRICKLE2 MACF1 CLSPN DNAH6	1.26e-05	196	116	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	SYNE1 CFAP43 PRICKLE2 MACF1 CLSPN DNAH6	1.26e-05	196	116	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ERMN ZBTB37 STARD9 ZNF292 RGPD5	1.30e-05	197	116	6	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C SYNE1 KSR2 MDGA2 ATP2B1 UNC79	1.34e-05	198	116	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C SYNE1 KSR2 MDGA2 ATP2B1 UNC79	1.34e-05	198	116	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C SYNE1 KSR2 MDGA2 ATP2B1 UNC79	1.34e-05	198	116	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C SYNE1 KSR2 MDGA2 ATP2B1 UNC79	1.34e-05	198	116	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 ATP13A4 ZNF407 SNX25 PRICKLE2 KDM6A	1.34e-05	198	116	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GPM6B SYNE1 AOX1 AKAP12 MACF1 PALLD	1.38e-05	199	116	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GPM6B SYNE1 AOX1 AKAP12 MACF1 PALLD	1.38e-05	199	116	6	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GPM6B SYNE1 AOX1 AKAP12 PLXNA4 MACF1	1.41e-05	200	116	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C GPM6B FRAS1 AKAP12 PHACTR3 PALLD	1.41e-05	200	116	6	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CACNA1C GPM6B FRAS1 PHACTR3 MACF1 PALLD	1.41e-05	200	116	6	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1C SYNE1 KSR2 MDGA2 ATP2B1 UNC79	1.41e-05	200	116	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 FRYL KMT2C SF3B1 MACF1 ZNF292	1.41e-05	200	116	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CACNA1C GPM6B FRAS1 PHACTR3 MACF1 PALLD	1.41e-05	200	116	6	a510deaada669e690329183e18df02870bd204b3
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C SYNE1 AOX1 AKAP12 STARD9 C3	1.41e-05	200	116	6	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C SYNE1 AOX1 AKAP12 STARD9 C3	1.41e-05	200	116	6	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	MYH9 SLC2A3 KMT2C SF3B1 USP7 MACF1	1.41e-05	200	116	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1C GPM6B FRAS1 PHACTR3 MACF1 PALLD	1.41e-05	200	116	6	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|LA / Chamber and Cluster_Paper	CACNA1C MYH9 XIRP2 DISP2 PALLD	4.17e-05	147	116	5	8970eb6b82589f39439c61a57d999661ec8342de
ToppCell	NS-moderate-d_07-13-Myeloid-Mast_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MDGA2 STAP1 AKAP12 SCG2 LYL1	5.53e-05	156	116	5	17c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCell	CV-Mild-4\|Mild / Virus stimulation, Condition and Cluster	GPM6B SLC2A3 ZFYVE9 DIAPH3 POLQ	6.23e-05	160	116	5	2e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPM6B AKAP12 PHACTR3 MACF1 PALLD	6.42e-05	161	116	5	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	USP34 SLC2A3 LRRC37A MACF1 KDM6A	6.61e-05	162	116	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A1 SCG2 PHACTR3 DNAH6 FAM131B	6.61e-05	162	116	5	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	367C-Fibroblasts-Fibroblast-F\|367C / Donor, Lineage, Cell class and subclass (all cells)	AOX1 AKAP12 C3 DIAPH3 AHNAK2	7.42e-05	166	116	5	2887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SETD1B HECTD4 CFAP43 ARID1A RPRD2	7.42e-05	166	116	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	367C-Fibroblasts-Fibroblast-F-\|367C / Donor, Lineage, Cell class and subclass (all cells)	AOX1 AKAP12 C3 DIAPH3 AHNAK2	7.42e-05	166	116	5	1cc291a04f4144abba4aca7badeb7776db05d903
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KSR2 TMEM196 SCG2 DISP2 UNC79	7.85e-05	168	116	5	0f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPPA2 BLM DIAPH3 CLSPN POLQ	8.07e-05	169	116	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AKAP12 BLM TMEM196 DIAPH3 CLSPN	8.07e-05	169	116	5	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BLM DISP2 DIAPH3 CLSPN POLQ	8.53e-05	171	116	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BLM DISP2 DIAPH3 CLSPN POLQ	8.53e-05	171	116	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	BLM SIK2 CCAR2 KDM6A PRRC2B	9.01e-05	173	116	5	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C FRAS1 FRYL PDE4DIP SEZ6L	9.26e-05	174	116	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	moderate-Myeloid-Mast_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MDGA2 STAP1 AKAP12 SCG2 LYL1	9.51e-05	175	116	5	bbd2971bc6d69e507f90a637834d0936c205c590
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SYNE1 CDH23 SLC2A3 PLXNA4 LYL1	1.00e-04	177	116	5	84591e28482ab62a5ef41e61043eb64912766356
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	AKAP12 PLXNA4 SIK2 PPIP5K1 TLN2	1.00e-04	177	116	5	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SYNE1 CDH23 SLC2A3 PLXNA4 LYL1	1.00e-04	177	116	5	4bc100062891d07cacd10ffba38966cc6302c92f
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SYNE1 CDH23 SLC2A3 PLXNA4 LYL1	1.00e-04	177	116	5	9f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C FRAS1 KSR2 PDE4DIP SEZ6L	1.03e-04	178	116	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SLC11A2 KSR2 PLCL2 REPS2	1.11e-04	181	116	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 APBA1 MDGA2 PHACTR3 PALLD	1.11e-04	181	116	5	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 APBA1 MDGA2 PHACTR3 PALLD	1.11e-04	181	116	5	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA1C MYH9 XIRP2 PDE4DIP PALLD	1.14e-04	182	116	5	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP12 MACF1 ATP2B1 KDM6A FILIP1L	1.14e-04	182	116	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	FRAS1 AOX1 PLXNA4 C3 DIAPH3	1.20e-04	184	116	5	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	(7)_DC_activated\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SLC12A1 SAMD13 STRA6 PALLD FAM131B	1.20e-04	184	116	5	b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SLC11A2 KSR2 PLCL2 REPS2	1.23e-04	185	116	5	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP12 MACF1 ATP2B1 KDM6A FILIP1L	1.23e-04	185	116	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C MYH9 AKAP12 PLXNA4 FILIP1L	1.23e-04	185	116	5	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM196 SCG2 PHACTR3 UNC79 SEZ6L	1.27e-04	186	116	5	2fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM196 SCG2 PHACTR3 UNC79 SEZ6L	1.27e-04	186	116	5	ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM196 SCG2 PHACTR3 UNC79 SEZ6L	1.27e-04	186	116	5	714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SYNE1 CFAP43 DIAPH3 REPS2	1.27e-04	186	116	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RGPD1 PRICKLE2 STRA6 ATP2B1 SEZ6L	1.30e-04	187	116	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	CACNA1C AOX1 AKAP12 TLN2 C3	1.33e-04	188	116	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C XIRP2 PDE4DIP PLCL2 PALLD	1.36e-04	189	116	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6B FRAS1 SLC11A2 KSR2 PLCL2	1.36e-04	189	116	5	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	GPM6B PABPC4L AKAP12 MACF1 PALLD	1.36e-04	189	116	5	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SLC11A2 KSR2 PLCL2 REPS2	1.36e-04	189	116	5	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CACNA1C MYH9 XIRP2 PDE4DIP PALLD	1.36e-04	189	116	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	CACNA1C MYH9 XIRP2 PDE4DIP PALLD	1.40e-04	190	116	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BLM STARD9 DIAPH3 CLSPN POLQ	1.40e-04	190	116	5	31de1727822e9818652946dfb962daee77ffad68
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	USP34 SLC11A2 HECTD4 ARID1A UBR5 ATP2B1 KDM6A PALLD	5.53e-06	188	116	8	4845_DN
Drug	Amphotericin B [1397-89-3]; Down 200; 4.4uM; MCF7; HT_HG-U133A	CUL2 KDM5A AOX1 MORC2 ZFYVE9 TLN2 SLC12A7 PRRC2B	6.96e-06	194	116	8	3303_DN
Drug	Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A	SLC11A2 SYNE1 UBR4 ZFYVE9 PDE4DIP USP7 TLN2 PALLD	7.51e-06	196	116	8	2958_UP
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SLC11A2 ARID1A PDE4DIP ETAA1 TLN2 STRA6 REPS2 KDM6A	8.09e-06	198	116	8	1544_DN
Drug	Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; PC3; HG-U133A	SLC11A2 KDM5A ACTL6A AKAP12 PLCL2 ATP2B1 KDM6A SEZ6L	8.09e-06	198	116	8	1902_UP
Disease	Malignant neoplasm of breast	NCOA2 MYH9 SYNE1 UBR4 LRRC37A2 ARID1A AKAP12 LRRC37A TRMT2A SCP2 MACF1 EXOC3L1 CLSPN REPS2 TP53BP2	1.37e-05	1074	112	15	C0006142
Disease	autosomal recessive spinocerebellar ataxia 20 (implicated_via_orthology)	SNX13 SNX25	1.43e-05	2	112	2	DOID:0080066 (implicated_via_orthology)
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	ATP2B1 MED13 ZNF292	3.48e-05	17	112	3	DOID:0060307 (is_implicated_in)
Disease	Immunologic Deficiency Syndromes	CACNA1C BLM C3	8.92e-05	23	112	3	C0021051
Disease	MYELODYSPLASTIC SYNDROME	BLM SF3B1 LYL1 SLX4	1.25e-04	67	112	4	C3463824
Disease	adenoid cystic carcinoma (is_implicated_in)	KMT2C KDM6A	1.42e-04	5	112	2	DOID:0080202 (is_implicated_in)
Disease	Klatskin's tumor (is_implicated_in)	ARID1A KMT2C	1.42e-04	5	112	2	DOID:4927 (is_implicated_in)
Disease	Bladder Neoplasm	ARID1A KMT2C USP7 SLC12A7 KDM6A	2.00e-04	140	112	5	C0005695
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	VAPA ATP13A4 PSMC4	2.01e-04	30	112	3	DOID:332 (implicated_via_orthology)
Disease	Malignant neoplasm of urinary bladder	ARID1A KMT2C USP7 SLC12A7 KDM6A	2.07e-04	141	112	5	C0005684
Disease	laryngeal carcinoma (is_marker_for)	KMT2C UBR5	2.12e-04	6	112	2	DOID:2600 (is_marker_for)
Disease	Carcinoma, Lobular	MYH9 TP53BP2	2.12e-04	6	112	2	C0206692
Disease	Breast Carcinoma	NCOA2 MYH9 SYNE1 LRRC37A2 ARID1A AKAP12 LRRC37A REPS2 TP53BP2	2.17e-04	538	112	9	C0678222
Disease	Intellectual Disability	KDM5A SYNE1 ACTL6A KMT2C MACF1 STRA6 MED13 ZNF292	3.14e-04	447	112	8	C3714756
Disease	unipolar depression, bipolar disorder	CACNA1C ATP13A4 SYNE1 STARD9 RPRD2	3.30e-04	156	112	5	EFO_0003761, MONDO_0004985
Disease	Carcinoma, Transitional Cell	ARID1A KMT2C KDM6A	5.11e-04	41	112	3	C0007138
Disease	Leukemia, Myelocytic, Acute	BLM KMT2C SF3B1 LYL1 SLX4	5.29e-04	173	112	5	C0023467
Disease	Prostatic Neoplasms	NCOA2 AOX1 ARID1A KMT2C SF3B1 USP7 RPRD2 KDM6A ZNF292	5.80e-04	616	112	9	C0033578
Disease	Malignant neoplasm of prostate	NCOA2 AOX1 ARID1A KMT2C SF3B1 USP7 RPRD2 KDM6A ZNF292	5.80e-04	616	112	9	C0376358
Disease	pneumonia (implicated_via_orthology)	SLC11A2 C3	6.30e-04	10	112	2	DOID:552 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	NCOA2 MYH9 SYNE1 LRRC37A2 AKAP12 LRRC37A REPS2 TP53BP2	8.99e-04	525	112	8	C4704874
Disease	Mammary Neoplasms, Human	NCOA2 MYH9 SYNE1 LRRC37A2 AKAP12 LRRC37A REPS2 TP53BP2	8.99e-04	525	112	8	C1257931
Disease	alcohol use disorder (implicated_via_orthology)	KDM5A ACTL6A ARID1A UNC79 KDM6A	9.07e-04	195	112	5	DOID:1574 (implicated_via_orthology)
Disease	Mammary Neoplasms	NCOA2 MYH9 SYNE1 LRRC37A2 AKAP12 LRRC37A REPS2 TP53BP2	9.21e-04	527	112	8	C1458155
Disease	malignant pleural mesothelioma (is_marker_for)	NCOA2 KDM6A	1.26e-03	14	112	2	DOID:7474 (is_marker_for)
Disease	Colorectal Carcinoma	SLC11A2 SYNE1 ARID1A FBXO30 AKAP12 KMT2C ETAA1 KDM6A ZNF292	1.45e-03	702	112	9	C0009402
Disease	Malignant Neoplasms	ARID1A BLM SF3B1 KDM6A	1.46e-03	128	112	4	C0006826
Disease	Cardiovascular Abnormalities	STRA6 ZNF292	1.65e-03	16	112	2	C0243050
Disease	Dystonia, Limb	SCP2 SLC30A10	1.87e-03	17	112	2	C0751093
Disease	Dystonia, Diurnal	SCP2 SLC30A10	1.87e-03	17	112	2	C0393610
Disease	Antibody Deficiency Syndrome	CACNA1C C3	1.87e-03	17	112	2	C0003257
Disease	lung non-small cell carcinoma (is_implicated_in)	NCOA2 ARID1A KMT2C KDM6A	1.98e-03	139	112	4	DOID:3908 (is_implicated_in)
Disease	Dystonia, Paroxysmal	SCP2 SLC30A10	2.10e-03	18	112	2	C0393588
Disease	stomach cancer (is_implicated_in)	ARID1A KMT2C KDM6A	2.62e-03	72	112	3	DOID:10534 (is_implicated_in)
Disease	intellectual disability (implicated_via_orthology)	GPM6B KDM5A UBR4	2.95e-03	75	112	3	DOID:1059 (implicated_via_orthology)
Disease	prostate cancer (is_marker_for)	NCOA2 KDM5A KMT2C KDM6A	3.00e-03	156	112	4	DOID:10283 (is_marker_for)
Disease	colorectal carcinoma (is_implicated_in)	NCOA2 AKAP12	3.14e-03	22	112	2	DOID:0080199 (is_implicated_in)
Disease	progranulin measurement	NCOA2 CDH23	3.14e-03	22	112	2	EFO_0004625
Disease	Nasopharyngeal carcinoma	SYNE1 ARID1A	3.14e-03	22	112	2	C2931822
Disease	mean corpuscular hemoglobin concentration	SLC11A2 SETD1B LRRC37A2 HECTD4 SNX13 UBR5 PLCL2 MACF1 CLSPN SLC12A7 MED13	3.23e-03	1105	112	11	EFO_0004528
Disease	Intrahepatic Cholangiocarcinoma	ARID1A KMT2C	3.73e-03	24	112	2	C0345905
Disease	Attention deficit hyperactivity disorder	MED13 ZNF292	3.73e-03	24	112	2	C1263846
Disease	Extrahepatic Cholangiocarcinoma	ARID1A KMT2C	3.73e-03	24	112	2	C3805278
Disease	stomach carcinoma (is_marker_for)	KDM5A KMT2C	3.73e-03	24	112	2	DOID:5517 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EMPNENDKLNDMEPS	VAPA	131	Q9P0L0
SEMEFSSLQDMPKEL	CCAR2	681	Q8N163
MDSAAKDEMQPALSP	EXOC3L1	1	Q86VI1
MEMKLPGQEGFEASS	SLC4A9	1	Q96Q91
AMDELDNISNMPEGL	CFAP43	1351	Q8NDM7
GLEEQGMENMSEVKE	CRYBG3	1261	Q68DQ2
EMLSSQERMKVQGSP	AKAP12	501	Q02952
SEMQEEMKGSVEEPK	AKAP12	651	Q02952
ELTMSPTAPEKMESN	ATP13A4	1016	Q4VNC1
NMEAISPLKNGMVED	ACTL6A	81	O96019
ASEMTMEDMAPGQLS	CAMTA2	871	O94983
SMMTGFAPDTDDLKQ	C3	1406	P01024
KQGMSDRVVDDLNPM	RAD54L2	881	Q9Y4B4
EMKTEGDETGVMDNL	DIAPH3	1051	Q9NSV4
MMATDQDEGPNGELT	CDH23	2531	Q9H251
KMMALEQGPDGTQDL	DISP2	876	A7MBM2
QNDDELPMKEGDCMT	TP53BP2	1071	Q13625
QDGAAMEMQPLKSEE	ATP2B1	326	P20020
QSMLVVPKGEDQEMD	AOX1	756	Q06278
PEMDSLMDMLASTQG	PCP2	61	Q8IVA1
SMDEQELENMLKPFG	RBMS1	151	P29558
TPDMSLQNMKGTERV	RGPD5	1411	Q99666
TPDMSLQNMKGTERV	RGPD8	1411	O14715
PSMTSSKGGQEDMNL	ARID1A	616	O14497
NNEKVFLMDPNTSDM	FRAS1	3666	Q86XX4
DPELDMGDKKSMFNE	KMT2C	2761	Q8NEZ4
QMNAPEEMDDASPEK	MAP10	326	Q9P2G4
DFMENTNMPEGTISE	LRRC37A2	1401	A6NM11
DFMENTNMPEGTISE	LRRC37A	1401	A6NMS7
GMRVKTEPMDADDSN	MED7	181	O43513
MDEENMTKSEEQQPL	KSR2	1	Q6VAB6
GEGMEESQSPMKTDL	KDM6A	856	O15550
SDIGKMPAISDQDMN	PLXNA4	1816	Q9HCM2
QMSNKEPEDMITGER	FRYL	536	O94915
INSEGEFIPESMDQM	MAP3K2	186	Q9Y2U5
MVLGPEQKMSDDSVS	SLC11A2	1	P49281
PGQQDKDMFQETMEA	MYH9	311	P35579
KTPMSAEMREEQGNQ	PANX1	381	Q96RD7
EVDDAMQGKLENNMP	HECTD4	971	Q9Y4D8
NSSMEDKMLKENPEE	ERMN	71	Q8TAM6
MKPAMETAAEENTEQ	GPM6B	1	Q13491
MLPSLQESMDGDEKE	C17orf75	1	Q9HAS0
QEAMMDETPDSSKLQ	KDM5A	861	P29375
MDGEDMSVNSTQEPL	FAM131B	146	Q86XD5
DKEVAMPDGSMQMES	MDGA2	481	Q7Z553
IEETTAQQEMMKPGQ	MACF1	1291	Q9UPN3
AQQEMMKPGQAEDSR	MACF1	1296	Q9UPN3
APQDEKPTTNSMLDM	ETAA1	141	Q9NY74
EEEVMTQFMKIPGDS	MORC2	181	Q9Y6X9
QSPMEDQGEMEREVK	PALLD	221	Q8WX93
SMPDLSKDSGMNVSE	PRICKLE2	571	Q7Z3G6
AKTVQFGQELPMDME	DNAH6	4036	Q9C0G6
EKMSMQELNPETSTD	BLM	346	P54132
NEDEGMDEEKPRNMS	CACNA1C	451	Q13936
KADGQTPVSMQDMLT	CYP46A1	171	Q9Y6A2
TSTEDLMNLEQGMSP	FILIP1L	961	Q4L180
DMQMKEPLPSEVTSN	POLQ	1506	O75417
SMQKDTPQEMEQTRS	CUL2	656	Q13617
MSSQSLDKAAEDMPE	APBA1	281	Q02410
VMPASTENGDKITMQ	ELF2	441	Q15723
AQAEVGPTMTEKAEM	LYL1	6	P12980
MEMNSIEPAKETTTN	SLC2A3	481	P11169
LNDPKMSETERQSME	KCMF1	296	Q9P0J7
GGTSENDDPSKMVMV	KATNA1	341	O75449
DMKQTIMETLEQGPA	EXOC3	706	O60645
DIGMLNTSVPNDMDE	FBXO30	206	Q8TB52
SAPTSLQEEEMPMKQ	SLC22A7	531	Q9Y694
MGGEESQSPTMESEK	RPRD2	341	Q5VT52
GKNMALFEEEMDSNP	SLC12A7	66	Q9Y666
VKDDANMEQMEPSVS	DPPA2	31	Q7Z7J5
SPEDATKAMTEMNGR	PABPC4L	341	P0CB38
TPDMSLQNMKGTERV	RGPD1	1396	P0DJD0
MMEQDAESKTCNPDG	PHACTR3	116	Q96KR7
LPDSLAEGMTKMSDN	SNX13	721	Q9Y5W8
VSDLAPGQSGMDDMK	XAB2	756	Q9HCS7
MSENLDNEGPKPMES	TRMT2A	1	Q8IZ69
EAPQEDTSPMALMDK	SEZ6L	231	Q9BYH1
EADSSIMMLTSDQKP	PSMC4	146	P43686
ESPQEEGKEMFATMS	SYNE1	776	Q8NF91
ELGMEGEKSSAEDQM	SYNE1	6281	Q8NF91
QMISNKDEMGPRDEA	SNX25	411	Q9H3E2
EDEGAEMSQRMGKEN	PLCL2	586	Q9UPR0
ALNSEKNFPMDMSDD	SCG2	136	P13521
QSLPSNMMETSIDEG	SIK2	441	Q9H0K1
LLKESDSMMVDPTND	SLC12A1	286	Q13621
MLSVDMENKENGSVG	SAMD13	21	Q5VXD3
EKMDEGQQSSGEDME	SETD1B	626	Q9UPS6
EMMDPASLEAEADQG	NSMCE4A	66	Q9NXX6
DKAPQALMMDGSTQT	STARD9	3716	Q9P2P6
SMPFIKEGDGSNMDQ	MED13	956	Q9UHV7
AQEMMTDLPSSFEEK	SCP2	256	P22307
EDEGMQLLQTKDSMA	STRA6	611	Q9BX79
SEDQPESLKTGQMMD	SLX4	31	Q8IY92
DMSLPSMQGDLKTTD	AHNAK2	1361	Q8IVF2
DMSLPSMQGDLKTTD	AHNAK2	2186	Q8IVF2
DMSLPSMQGDLKTTD	AHNAK2	2681	Q8IVF2
DMSIPSMQGDLKTTD	AHNAK2	4496	Q8IVF2
LNKQEKESSMGDPME	CLSPN	961	Q9HAW4
QLPGMDMIKQEGDTT	NCOA2	1446	Q15596
KPVEMDIQAGDVSSM	XIRP2	1011	A4UGR9
SFNTQNEPEDMMKKE	SLC30A10	216	Q6XR72
MAEKEITDNMSNGGP	TMEM196	156	Q5HYL7
KQPSSQVEESAMMGV	ZBTB37	336	Q5TC79
AEMDKGLSELSPMQQ	TTC6	16	Q86TZ1
MDDEDKQQETQSPTM	REPS2	176	Q8NFH8
MQTEDRTMKSVNDQP	SF3B1	446	O75533
EATEMLQKNPSLGNM	STAP1	186	Q9ULZ2
SNDPDMSVMKDISIG	ZNF292	2701	O60281
VLNTSREPSQMEMKG	PRRC2B	2121	Q5JSZ5
LDNLMEMKSNPETDD	SCFD1	551	Q8WVM8
QKSFMETAMDVDSPE	UBR3	1201	Q6ZT12
TKPEGTAMQMSRQSE	TSSK1B	326	Q9BXA7
EMMTKSVTNPEELGG	TLN2	1871	Q9Y4G6
GSADMSKNIIMPEEE	ZNF407	1086	Q9C0G0
MDKQPLNTGEQKDMT	USP34	1966	Q70CQ2
FTESKLPQMETEGMD	UBR4	2591	Q5T4S7
KAGEQQLSEPEDMEM	USP7	11	Q93009
QLSEPEDMEMEAGDT	USP7	16	Q93009
EEMKTNQGSMENLCP	PPIP5K1	936	Q6PFW1
ESTEKDMNSEKQMDP	ZFYVE9	201	O95405
SMIMFGSQENKDPLS	UBR5	1341	O95071
KENQDASNLTVPMTM	UNC79	56	Q9P2D8
NAELKEQMGEAMSDG	PDE4DIP	1056	Q5VU43