Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell fate specification

MTA2 POU4F1 TEAD4 MBD3 OLIG3 MTA1 MTA3 GLI3 TBX20

1.62e-061231849GO:0001708
GeneOntologyCellularComponentNuRD complex

MTA2 MBD3 MTA1 MTA3

1.32e-05171864GO:0016581
GeneOntologyCellularComponentCHD-type complex

MTA2 MBD3 MTA1 MTA3

1.32e-05171864GO:0090545
MousePhenoabnormal mitotic spindle morphology

CCP110 PRICKLE1 BUB1 PKHD1 PCNT

2.31e-05361355MP:0009760
MousePhenodiluted coat color

MYO5A DTNBP1 VAC14 DOCK7 CORIN AP3D1

3.44e-05641356MP:0000371
DomainLeu-rich_rpt

RANGAP1 LRFN1 CARMIL3 CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 FBXL20 ADGRA3 LRRC71

1.10e-0827118316IPR001611
Domain-

RANGAP1 LRFN1 CARMIL3 NAIP CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 FBXL20 ADGRA3 LRRC71

1.88e-08321183173.80.10.10
DomainL_dom-like

RANGAP1 LRFN1 CARMIL3 NAIP CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 FBXL20 ADGRA3 LRRC71

2.58e-0832818317IPR032675
DomainLRR_8

LRFN1 CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 ADGRA3

1.24e-0717118312PF13855
DomainLRR_TYP

LRFN1 CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 ADGRA3

1.81e-0717718312SM00369
DomainLeu-rich_rpt_typical-subtyp

LRFN1 CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 ADGRA3

1.81e-0717718312IPR003591
DomainLRR_1

RANGAP1 CPN2 TLR9 TLR6 NRROS LRIT3 LRCH3 LRIG3 PXDN LRRC20 SLIT3 FBXL20 ADGRA3

2.58e-0721918313PF00560
DomainAAA

NAIP PEX1 MCM4 RFC1 ABCA8 MDN1 ABCB8 ABCG2 ASCC3

1.25e-051441839SM00382
DomainAAA+_ATPase

NAIP PEX1 MCM4 RFC1 ABCA8 MDN1 ABCB8 ABCG2 ASCC3

1.25e-051441839IPR003593
DomainLRRCT

CPN2 TLR6 LRIG3 SLIT3 ADGRA3

1.39e-05321835PF01463
DomainLRR_6

RANGAP1 CARMIL3 TLR9 NRROS FBXL20 LRRC71

1.59e-05551836PF13516
DomainCys-rich_flank_reg_C

LRFN1 CPN2 TLR6 LRIG3 PXDN SLIT3 ADGRA3

2.91e-05901837IPR000483
DomainLRRCT

LRFN1 CPN2 TLR6 LRIG3 PXDN SLIT3 ADGRA3

2.91e-05901837SM00082
DomainLRR

LRFN1 CPN2 TLR9 TLR6 NRROS LRIT3 LRIG3 PXDN SLIT3 ADGRA3

3.00e-0520118310PS51450
DomainBAH

MTA2 MTA1 MTA3

1.44e-04111833PS51038
DomainBAH_dom

MTA2 MTA1 MTA3

1.44e-04111833IPR001025
DomainBAH

MTA2 MTA1 MTA3

1.44e-04111833SM00439
DomainBAH

MTA2 MTA1 MTA3

1.44e-04111833PF01426
DomainZnF_GATA

MTA2 MTA1 MTA3

1.91e-04121833SM00401
DomainELM2_dom

MTA2 MTA1 MTA3

2.46e-04131833IPR000949
DomainELM2

MTA2 MTA1 MTA3

2.46e-04131833PF01448
DomainELM2

MTA2 MTA1 MTA3

2.46e-04131833PS51156
DomainELM2

MTA2 MTA1 MTA3

2.46e-04131833SM01189
DomainZnf_GATA

MTA2 MTA1 MTA3

3.86e-04151833IPR000679
DomainGATA

MTA2 MTA1 MTA3

3.86e-04151833PF00320
DomainGATA_ZN_FINGER_1

MTA2 MTA1 MTA3

4.72e-04161833PS00344
DomainGATA_ZN_FINGER_2

MTA2 MTA1 MTA3

4.72e-04161833PS50114
DomainCaMBD

KCNN2 KCNN3

5.66e-0441832PF02888
DomainCaM-bd_dom

KCNN2 KCNN3

5.66e-0441832IPR004178
DomainCaMBD

KCNN2 KCNN3

5.66e-0441832SM01053
DomainK_chnl_Ca-activ_SK

KCNN2 KCNN3

5.66e-0441832IPR015449
DomainSPHK1-interactor_AKAP_110

AKAP3 AKAP11

5.66e-0441832IPR008382
DomainAKAP_110

AKAP3 AKAP11

5.66e-0441832PF05716
DomainSK_channel

KCNN2 KCNN3

5.66e-0441832PF03530
DomainBiotin_BS

ACACB PC

9.36e-0451832IPR001882
DomainMyosin_S1_N

MYO5A MYO5B

9.36e-0451832IPR008989
DomainBiotin_COase_C

ACACB PC

9.36e-0451832IPR005482
DomainBC

ACACB PC

9.36e-0451832PS50979
DomainBiotin_carb_C

ACACB PC

9.36e-0451832SM00878
DomainBiotin_carb_C

ACACB PC

9.36e-0451832PF02785
DomainBiotin_carboxylation_dom

ACACB PC

9.36e-0451832IPR011764
DomainBIOTIN

ACACB PC

9.36e-0451832PS00188
DomainUDPGT

UGT1A5 UGT1A4 UGT2B28

1.08e-03211833PF00201
DomainUDPGT

UGT1A5 UGT1A4 UGT2B28

1.08e-03211833PS00375
DomainUDP_glucos_trans

UGT1A5 UGT1A4 UGT2B28

1.08e-03211833IPR002213
DomainIQ

IQCH RASGRF1 MYO5A MYO5B MYO18B

1.20e-03811835SM00015
DomainZnf_C2HC

MYT1 L3MBTL1

1.40e-0361832IPR002515
DomainDilute_dom

MYO5A MYO5B

1.40e-0361832IPR002710
Domainzf-C2HC

MYT1 L3MBTL1

1.40e-0361832PF01530
DomainRudment_hybrid_motif

ACACB PC

1.40e-0361832IPR011054
DomainDIL

MYO5A MYO5B

1.40e-0361832PF01843
DomainDILUTE

MYO5A MYO5B

1.40e-0361832PS51126
DomainDIL

MYO5A MYO5B

1.40e-0361832SM01132
DomainARM-like

RANGAP1 DNAJC13 MROH2A HEATR5A TRIP12 VAC14 XPO6 STAG3 AP3D1

1.41e-032701839IPR011989
DomainIQ_motif_EF-hand-BS

IQCH RASGRF1 MYO5A MYO5B MYO18B

1.92e-03901835IPR000048
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACB PC

1.94e-0371832IPR005479
DomainBC-like_N

ACACB PC

1.94e-0371832IPR005481
DomainZF_CCHHC

MYT1 L3MBTL1

1.94e-0371832PS51802
DomainCPSase_L_D2

ACACB PC

1.94e-0371832PF02786
DomainPept_C14A_CASP1-typ

CASP5 CASP12

1.94e-0371832IPR017350
DomainBiotin_carb_N

ACACB PC

1.94e-0371832PF00289
DomainSANT_dom

MTA2 MTA1 MTA3

2.04e-03261833IPR017884
DomainIQ

IQCH RASGRF1 MYO5A MYO5B MYO18B

2.22e-03931835PS50096
DomainCARD

CASP5 BIRC2 CASP12

2.53e-03281833PF00619
DomainSANT

MTA2 MTA1 MTA3

2.53e-03281833PS51293
DomainBIR

NAIP BIRC2

2.57e-0381832PF00653
DomainBIR_REPEAT_2

NAIP BIRC2

2.57e-0381832PS50143
DomainBIR

NAIP BIRC2

2.57e-0381832SM00238
Domain-

NAIP BIRC2

2.57e-03818321.10.1170.10
DomainBIR_rpt

NAIP BIRC2

2.57e-0381832IPR001370
DomainBIR_REPEAT_1

NAIP BIRC2

2.57e-0381832PS01282
DomainBiotin_lipoyl

ACACB PC

3.29e-0391832PF00364
DomainCARD

CASP5 BIRC2 CASP12

3.40e-03311833IPR001315
DomainIg_E-set

MYCBP2 PKHD1 ASCC3 PLXNA1 EPB42

3.60e-031041835IPR014756
DomainCARD

CASP5 BIRC2 CASP12

4.07e-03331833PS50209
DomainBIOTINYL_LIPOYL

ACACB PC

4.08e-03101832PS50968
DomainBiotin_lipoyl

ACACB PC

4.08e-03101832IPR000089
DomainGPS

ADGRG4 ADGRE3 ADGRA3

4.43e-03341833SM00303
DomainGPS

ADGRG4 ADGRE3 ADGRA3

4.81e-03351833PF01825
DomainMyb_DNA-binding

MTA2 MTA1 MTA3

4.81e-03351833PF00249
DomainHEAT_REPEAT

MROH2A HEATR5A VAC14 AP3D1

4.94e-03701834PS50077
DomainIQ

RASGRF1 MYO5A MYO5B MYO18B

5.20e-03711834PF00612
DomainGPS

ADGRG4 ADGRE3 ADGRA3

5.21e-03361833PS50221
DomainGPS

ADGRG4 ADGRE3 ADGRA3

5.63e-03371833IPR000203
DomainCaspase_his_AS

CASP5 CASP12

5.91e-03121832IPR016129
DomainCASPASE_CYS

CASP5 CASP12

5.91e-03121832PS01122
DomainPept_C14_p10

CASP5 CASP12

5.91e-03121832IPR002138
DomainSingle_hybrid_motif

ACACB PC

5.91e-03121832IPR011053
DomainCaspase_cys_AS

CASP5 CASP12

5.91e-03121832IPR033139
DomainCASPASE_P10

CASP5 CASP12

5.91e-03121832PS50207
DomainMyosin_head_motor_dom

MYO5A MYO5B MYO18B

6.07e-03381833IPR001609
DomainMYOSIN_MOTOR

MYO5A MYO5B MYO18B

6.07e-03381833PS51456
DomainMYB_LIKE

MTA2 MTA1 MTA3

6.07e-03381833PS50090
DomainMyosin_head

MYO5A MYO5B MYO18B

6.07e-03381833PF00063
DomainMYSc

MYO5A MYO5B MYO18B

6.07e-03381833SM00242
DomainARM-type_fold

DNAJC13 MROH2A HEATR5A TRIP12 ITPR1 VAC14 XPO6 STAG3 AP3D1

6.35e-033391839IPR016024
Domain-

DNAJC13 HEATR5A TRIP12 VAC14 XPO6 STAG3 AP3D1

6.36e-0322218371.25.10.10
DomainCASc

CASP5 CASP12

6.94e-03131832SM00115
Domain-

ACACB PC

6.94e-031318323.40.50.20
DomainPept_C14A

CASP5 CASP12

6.94e-03131832IPR015917
Pubmed

The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment.

MTA2 MBD3 MTA1 MTA3

4.21e-095189431036553
Pubmed

Identification and characterization of metastasis-associated gene/protein 1 (MTA1).

MTA2 MTA1 MTA3

1.58e-073189325315816
Pubmed

Structure, expression and functions of MTA genes.

MTA2 MTA1 MTA3

1.58e-073189326869315
Pubmed

Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

OR3A2 OR1E3 OR1G1 OR3A3

2.71e-071118948004088
Pubmed

Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development.

MTA2 MBD3 MTA1 MTA3

4.04e-0712189420720167
Pubmed

Identification of epilepsy genes in human and mouse.

CACNA1A MYO5A ITPR1 AP3D1

4.04e-0712189411700294
Pubmed

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

MTA2 MBD3 MTA1 MTA3

4.04e-0712189422560079
Pubmed

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.

MTA2 MBD3 MTA1 MTA3

5.81e-0713189419703393
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MTA2 COL5A1 RANGAP1 HYOU1 MYO5A MYCBP2 DHX57 MCM4 RFC1 TRIP12 DDX27 MDN1 NUP155 DOCK7 ASCC3 PCNT

6.54e-076531891622586326
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DNAJC13 VEZT VPS13C PEX1 DHX57 LRCH3 ITPR1 FAM171A1 LRIG3 VAC14 NUP155 TMF1 AKAP11 PLXNA1

7.77e-075041891434432599
Pubmed

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

MTA2 MBD3 MTA1 MTA3

8.10e-0714189416428440
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FOXM1 MTA2 EPHX1 LRFN1 VPS13C PEX1 BBS2 PTPN23 MCM4 MBD3 ITPR1 MED24 CASP12 HSF1 ANAPC7 STAG3 EP300

9.06e-077541891735906200
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

LRFN1 LRIT3 LRIG3 PXDN ADGRA3

1.10e-0634189518848646
Pubmed

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

MTA2 MBD3 MTA1 MTA3

1.10e-0615189425247294
Pubmed

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.

MTA2 MBD3 MTA1 MTA3

1.10e-0615189419927129
Pubmed

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.

OR3A2 OR1E3 OR1G1 OR3A3

1.46e-0616189410673334
Pubmed

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.

MTA2 MBD3 MTA1

1.57e-065189316462733
Pubmed

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.

MTA2 MBD3 MTA1 MTA3

2.44e-061818949790534
Pubmed

Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development.

MTA2 MBD3 MTA1 MTA3

2.44e-0618189423201013
Pubmed

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.

MTA2 MBD3 MTA1 MTA3

2.44e-0618189410444591
Pubmed

Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.

MTA2 MBD3 PCNT

3.12e-066189317626165
Pubmed

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

MTA2 RREB1 MBD3 MTA1 MTA3

4.60e-0645189521258344
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RANGAP1 DNAJC13 HYOU1 MYO5A MYO5B MYCBP2 VEZT PTPN23 DTNBP1 DDX27 ADD2 ITPR1 FAM171A1 CNNM1 NUP155 TMF1 PC PLK4 PCNT

5.06e-0610491891927880917
Pubmed

Mouse models of Hermansky Pudlak syndrome: a review.

DTNBP1 DOCK7 AP3D1

5.44e-06718939585243
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

DHX57 MCM4 TEAD4 RREB1 MBD3 INTS6 MTA3 ASCC3

6.10e-06177189826206133
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

EPHX1 VPS37C MRPS28 BBS2 BIRC2 PTPN23 RFC1 SPATA2 ZCCHC14 NUP155 BUB1 ASCC3 HSF1 OPLAH

6.30e-066041891438803224
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

ACACB MYCBP2 POLD2 MED24 CCNT1 XPO6 CDIPT BUB1 AKAP11

7.78e-06242189934011540
Pubmed

The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.

MTA2 MTA1 MTA3

8.67e-068189318067919
Pubmed

MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.

MTA2 MBD3 MTA3

8.67e-068189312705869
Pubmed

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation.

MTA2 MBD3 MTA3

8.67e-068189310471500
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

ACACB MCM4 RFC1 TRIP12 PC AP3D1

1.01e-0590189635654790
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

MTA2 PEX1 CCDC175 RFC1 ABCA8 MBD3 MTA1 MTA3 GLI3 KIF28P

1.14e-053211891032098917
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MTA2 VEZT RPP38 PEX1 BIRC2 RREB1 ABCA8 MBD3 CCNT1 LRIG3 INTS6 MTA1 MTA3 GLI3 SCAPER ASCC3 ANAPC7 EP300 FOXK1

1.21e-0511161891931753913
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

MTA2 RANGAP1 RFC1 MBD3 CCNT1 MTA1 MTA3 ANAPC7

1.24e-05195189819454010
Pubmed

RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene.

MTA2 MTA1 MTA3

1.30e-059189322926524
Pubmed

Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis.

MTA2 MTA1 MTA3

1.30e-059189326028330
Pubmed

Distribution of olfactory receptor genes in the human genome.

OR1N1 OR3A2 OR1G1 OR3A3

1.56e-052818949500546
Pubmed

SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis.

MTA2 MBD3 MTA1 EP300

1.56e-0528189434163012
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DNAJC13 MYO5A DHX57 TRIP12 PXDN DOCK7 ASCC3 AP3D1

1.60e-05202189833005030
Pubmed

Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress.

MTA2 MBD3 MTA1

1.84e-0510189320127688
Pubmed

PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.

MTA2 MTA1 MTA3

1.84e-0510189334180153
Pubmed

BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter.

MTA2 MBD3 MTA1

1.84e-0510189316091750
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

CCP110 MYCBP2 SPATA2 DOCK7 PLK4 PCNT

1.96e-05101189624613305
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

DNAJC13 ACACB MYCBP2 RREB1 GREB1L BUB1 DOCK7 TMF1 ASCC3 PC PCNT

2.01e-054181891134709266
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

MCM4 RFC1 TRIP12 VAC14 MTA1 MDN1 MTA3

2.17e-05153189726365490
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

LRFN1 PTPN23 GPR83 POLR3E SCAPER PDZD4

2.20e-05103189610819331
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FOXM1 RANGAP1 DNAJC13 MYCBP2 MCM4 RFC1 RREB1 TRIP12 MED24 MTA1 MDN1 XPO6 ZNF335 PLA2G4A HSF1

2.41e-057741891515302935
Pubmed

MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.

MTA2 MBD3 MTA1

2.52e-0511189315456747
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

RANGAP1 CCNT1 MTA1 MDN1 MTA3 GLI3 AKAP11 ASCC3 ANAPC7

2.61e-05282189923667531
Pubmed

Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding.

POU4F1 POU4F2

2.94e-05218928537352
Pubmed

Brn3 transcription factors control terminal osteoclastogenesis.

POU4F1 POU4F2

2.94e-052189217668438
Pubmed

Interplay of acetyltransferase EP300 and the proteasome system in regulating heat shock transcription factor 1.

HSF1 EP300

2.94e-052189224581496
Pubmed

PLK4 phosphorylation of CP110 is required for efficient centriole assembly.

CCP110 PLK4

2.94e-052189228562169
Pubmed

Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor.

POU4F1 POU4F2

2.94e-05218928995448
Pubmed

Methylene blue increases the amount of HSF1 through promotion of PKA-mediated increase in HSF1-p300 interaction.

HSF1 EP300

2.94e-052189228104499
Pubmed

Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells.

POU4F1 POU4F2

2.94e-05218928234287
Pubmed

The hedgehog processing pathway is required for NSCLC growth and survival.

HHAT DISP1

2.94e-052189222733134
Pubmed

Autoregulatory sequences are revealed by complex stability screening of the mouse brn-3.0 locus.

POU4F1 POU4F2

2.94e-052189210414983
Pubmed

Inhibition of MTA2 and MTA3 induces mesendoderm specification of human embryonic stem cells.

MTA2 MTA3

2.94e-052189233744762
Pubmed

Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid.

POU4F1 POU4F2

2.94e-05218927904822
Pubmed

P300 binds to and acetylates MTA2 to promote colorectal cancer cells growth.

MTA2 EP300

2.94e-052189224468085
Pubmed

NT-3 regulates expression of Brn3a but not Brn3b in developing mouse trigeminal sensory neurons.

POU4F1 POU4F2

2.94e-05218929582431
Pubmed

Down-regulation of the small conductance calcium-activated potassium channels in diabetic mouse atria.

KCNN2 KCNN3

2.94e-052189225605734
Pubmed

Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress.

FOXM1 HSF1

2.94e-052189223192351
Pubmed

Nuclear localization and dominant-negative suppression by a mutant SKCa3 N-terminal channel fragment identified in a patient with schizophrenia.

KCNN2 KCNN3

2.94e-052189211395478
Pubmed

Brn3a and Brn3b knockout mice display unvaried retinal fine structure despite major morphological and numerical alterations of ganglion cells.

POU4F1 POU4F2

2.94e-052189227391320
Pubmed

The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells.

MTA1 MTA3

2.94e-052189219363681
Pubmed

A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.

MCM4 FANCC

2.94e-052189224589582
Pubmed

Distribution of Ca2+-activated K channels, SK2 and SK3, in the normal and Hirschsprung's disease bowel.

KCNN2 KCNN3

2.94e-052189212778407
Pubmed

Role of SK channel activation in determining the action potential configuration in freshly isolated human atrial myocytes from the SKArF study.

KCNN2 KCNN3

2.94e-052189230922569
Pubmed

Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels.

KCNN2 KCNN3

2.94e-052189227874831
Pubmed

Imprinted gene in postnatal growth role.

RANGAP1 RASGRF1

2.94e-05218929603515
Pubmed

SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons.

KCNN2 KCNN3

2.94e-052189222554781
Pubmed

Overexpression of MTA1 inhibits the metastatic ability of ZR-75-30 cells in vitro by promoting MTA2 degradation.

MTA2 MTA1

2.94e-052189230642362
Pubmed

Expression of postsynaptic Ca2+-activated K+ (SK) channels at C-bouton synapses in mammalian lumbar -motoneurons.

KCNN2 KCNN3

2.94e-052189223129791
Pubmed

Assignment of the metastasis-associated gene (Mta1) to mouse chromosome band 12F and the metastasis-associated gene 2 (Mta2) to mouse chromosome band 19B by fluorescence in situ hybridization.

MTA2 MTA1

2.94e-052189211856890
Pubmed

Respiration and parturition affected by conditional overexpression of the Ca2+-activated K+ channel subunit, SK3.

KCNN2 KCNN3

2.94e-052189210988076
Pubmed

Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function.

KCNN2 KCNN3

2.94e-052189236502918
Pubmed

A novel isoform of SK2 assembles with other SK subunits in mouse brain.

KCNN2 KCNN3

2.94e-052189215797870
Pubmed

Function and regulation of MTA1 and MTA3 in malignancies of the female reproductive system.

MTA1 MTA3

2.94e-052189225319202
Pubmed

A single amino acid change converts an inhibitory transcription factor into an activator.

POU4F1 POU4F2

2.94e-05218928662774
Pubmed

Drug resistance of bladder cancer cells through activation of ABCG2 by FOXM1.

FOXM1 ABCG2

2.94e-052189229397866
Pubmed

Differential expression and subcellular localization of Copines in mouse retina.

POU4F1 POU4F2

2.94e-052189230866042
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

EPHX1 UGT1A5 UGT1A4 ABCG2 UGT2B28

3.07e-0566189519898482
Pubmed

Functions of Tat: the versatile protein of human immunodeficiency virus type 1.

FASLG CCNT1 EP300

3.35e-0512189319812265
Pubmed

Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.

MTA2 MBD3 MTA3

3.35e-0512189321937684
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MTA2 TRPM4 ARHGEF19 LRFN1 MYCBP2 MBD3 ZCCHC14 VAC14 MDN1 POMGNT2 XPO6 ZNF335 PC AP3D1 EP300 PLXNA1 FOXK1 PCNT

3.68e-0511051891835748872
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

MTA2 CCP110 DNAJC13 LRFN1 MRPS28 MYO5B MYCBP2 BBS2 MCM4 RREB1 DTNBP1 LRCH3 XPO6 GLI3 BUB1 DOCK7 HSF1 ANAPC7 FOXK1 CRTC2

3.76e-0513211892027173435
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

EPHX1 DHX57 RFC1 TRIP12 DDX27 MBD3 MED24 CCNT1 MDN1 MTA3 HASPIN ANAPC7

3.89e-055331891230554943
Pubmed

The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity.

MTA2 MTA1 MTA3

4.34e-0513189312920132
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CCP110 ACACB MYO5A RFC1 TRIP12 MDN1 ZNF335 PC

4.56e-05234189836243803
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RANGAP1 DNAJC13 HYOU1 MYO5A MYCBP2 RPP38 DHX57 TRIP12 MBD3 MTA1 CDIPT DOCK7 ASCC3 ANAPC7

4.64e-057241891436232890
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

CACNA1A MYO5A ITPR1 KCNN2 AP3D1

4.68e-0572189525917818
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MTA2 RANGAP1 DNAJC13 MRPS28 MYO5A MYCBP2 POLD2 RPP38 PTPN23 DHX57 MCM4 RFC1 TRIP12 DDX27 CCNT1 MDN1 NUP155 GRHPR ASCC3 AP3D1

5.23e-0513531892029467282
Pubmed

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

MTA2 MBD3 MTA1 MTA3

5.40e-0538189433283408
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

MROH2A UGT1A5 UGT1A4

5.50e-0514189321646302
Pubmed

NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

MTA2 MTA1 MTA3

5.50e-0514189325150861
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

MTA2 MBD3 MTA1 MTA3 EP300

5.70e-0575189525593309
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MTA2 RANGAP1 MRPS28 HYOU1 MYO5A MYCBP2 MCM4 RFC1 MBD3 ADD2 VAC14 MTA1 MDN1 DOCK7 ASCC3 ANAPC7 AP3D1 FOXK1

6.07e-0511491891835446349
Pubmed

Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo.

CASP5 FASLG CASP12

6.85e-0515189319801895
Cytoband6p22.2-p21.31

OR12D2 OR12D1

1.67e-04518926p22.2-p21.31
GeneFamilyPHD finger proteins|NuRD complex

MTA2 MBD3 MTA1 MTA3

1.67e-061214141305
GeneFamilyMyosins, class V

MYO5A MYO5B

1.80e-04314121100
GeneFamilyOlfactory receptors, family 12

OR12D2 OR12D1

1.80e-0431412160
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA2 MTA1 MTA3

1.97e-0415141382
GeneFamilyPotassium calcium-activated channels

KCNN2 KCNN3

8.87e-0461412255
GeneFamilyOlfactory receptors, family 3

OR3A2 OR3A3

8.87e-0461412150
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

CASP5 BIRC2 CASP12

1.62e-03301413959
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

NAIP BIRC2

1.64e-0381412419
GeneFamilyUDP glucuronosyltransferases

UGT1A5 UGT1A4 UGT2B28

1.95e-03321413363
GeneFamilyCD molecules|Toll like receptors

TLR9 TLR6

2.61e-03101412948
GeneFamilyOlfactory receptors, family 1

OR1N1 OR1E3 OR1G1

3.71e-03401413147
GeneFamilyCaspases|Caspase recruitment domain containing

CASP5 CASP12

4.45e-03131412468
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

HYOU1 MYCBP2 VPS13C GNPTAB MCM4 CCNT1 NUP155 KCNJ5-AS1

1.58e-0619118889454f642c3621370fa23640b631301346b300950
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NPHS1 ZNF133 TOB2 INTS6 KCNN3 EPB42 SERTAD1

3.54e-061501887744050a1b665c6989f37141348af3df7579a73c9
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

NPHS1 ZNF133 TOB2 INTS6 KCNN3 EPB42 SERTAD1

4.21e-061541887874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCP110 MYO5B RPP38 DND1 POMGNT2 PLXNA1 PDZD4

7.45e-061681887b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FOXM1 MCM4 FAM171A1 HHAT CENPI CMKLR1 STAG3

9.02e-06173188720889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FOXM1 MCM4 FAM171A1 HHAT CENPI CMKLR1 STAG3

9.02e-06173188746e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL5A1 GREB1L GPR83 HHAT SLIT3 KCNN3 PLXNA1

1.35e-05184188730fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL5A1 GREB1L GPR83 HHAT SLIT3 KCNN3 PLXNA1

1.35e-05184188796926efa220f03d0787322c9519bb9e8f64f74d0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRICKLE1 ABCA8 ADGRG4 GREB1L GLI3 SLIT3

1.55e-051881887ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRICKLE1 ABCA8 ADGRG4 GREB1L GLI3 SLIT3

1.66e-051901887efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GLS2 HTR2C RASGRF1 MYCBP2 ADD2 CNNM1 PDZD4

1.66e-051901887416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRICKLE1 ABCA8 PXDN GLI3 SLIT3 PLA2G4A

1.71e-051911887a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRICKLE1 ABCA8 PXDN GLI3 SLIT3 PLA2G4A

1.77e-0519218879093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRICKLE1 ABCA8 PXDN GLI3 SLIT3 PLA2G4A

1.77e-0519218879ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXM1 HYOU1 MCM4 BUB1 HASPIN KCNN3 PLK4

1.89e-0519418875a519538327029ad2b880ef9647e2ac6ab3961a4
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A MYCBP2 CARMIL3 VPS13C SCAPER ASCC3 PC

1.96e-0519518873e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A MYCBP2 CARMIL3 VPS13C SCAPER ASCC3 PC

1.96e-0519518877796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPHS1 MRPS28 COL6A5 MDN1 CMKLR1 TBX20

2.26e-05134188664979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 PRICKLE1 COL6A5 ABCA8 PLPPR4 KCNN3 CORIN

2.30e-05200188758b38f9a484ee94191091a0659ed62ebed2d4a14
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A5 UGT1A4 ABCG2

1.98e-0591853EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A5 UGT1A4 ABCG2

1.98e-0591853EFO_0801036
Diseaseinsomnia, bilirubin measurement

MROH2A UGT1A5 UGT1A4

3.86e-05111853EFO_0004570, EFO_0004698
Diseasep-cresol glucuronide measurement

UGT1A5 UGT1A4 XPO6

5.12e-05121853EFO_0800079
Diseaseserum metabolite measurement

GLS2 RASGRF1 UGT1A5 SGPP2 UGT1A4 MTA1 HHAT DNAH17 ABCB8 DOCK7 HEY2 PLA2G4A TAAR1 ABCG2 FBXL20 FOXK1 OPLAH

1.02e-0494518517EFO_0005653
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

DTNBP1 DOCK7 AP3D1

1.04e-04151853DOID:2223 (implicated_via_orthology)
DiseaseBrugada syndrome

HEY2 MYO18B TBX20

2.18e-04191853MONDO_0015263
Diseasehereditary spherocytosis type 1 (implicated_via_orthology)

ADD2 EPB42

2.33e-0441852DOID:0110916 (implicated_via_orthology)
Diseasehearing threshold measurement, pure tone hearing measurement

TBC1D8 ADGRA3

3.86e-0451852EFO_0007617, EFO_0007618
Diseasepre-eclampsia (is_implicated_in)

EPHX1 FASLG CORIN

5.04e-04251853DOID:10591 (is_implicated_in)
Diseasetoxic encephalopathy (is_implicated_in)

EPHX1 ABCG2

5.77e-0461852DOID:3602 (is_implicated_in)
Diseaseceramide measurement

BBS2 ANKMY1 LRIG3 MDN1 CORIN FBXL20 ADGRA3

7.35e-042351857EFO_0010222
DiseaseAutoimmune Lymphoproliferative Syndrome Type 2B

COL5A1 FASLG

8.04e-0471852C1846545
Diseasesubstance-related disorder (implicated_via_orthology)

HTR2C FASLG

8.04e-0471852DOID:303 (implicated_via_orthology)
DiseaseLeukemia, Myelocytic, Acute

EPHX1 POU4F1 FANCC PXDN EP300 CNR2

8.05e-041731856C0023467
DiseaseBipolar Disorder

CACNA1A HTR2C RASGRF1 DTNBP1 ITPR1 KCNN3 PLA2G4A PC CNR2 PCNT

9.09e-0447718510C0005586
DiseaseX-11793--oxidized bilirubin measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0021260
DiseaseSuccinimide measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0022118
DiseaseX-11530 measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0800696
DiseaseX-10458 measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0800692
Diseasecardiac arrest (biomarker_via_orthology)

TRPM4 ITPR1

1.07e-0381852DOID:0060319 (biomarker_via_orthology)
DiseaseX-24849 measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0800909
Diseasecerebellar ataxia (implicated_via_orthology)

CACNA1A VPS13C

1.07e-0381852DOID:0050753 (implicated_via_orthology)
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0802740
DiseaseX-16946 measurement

UGT1A5 UGT1A4

1.07e-0381852EFO_0800766
Diseasetea consumption measurement

TOB2 MYT1 FRMD4B PKHD1 ABCG2

1.35e-031291855EFO_0010091
DiseaseX-11442 measurement

UGT1A5 UGT1A4

1.37e-0391852EFO_0021236
DiseaseX-11441 measurement

UGT1A5 UGT1A4

1.37e-0391852EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A5 UGT1A4

1.37e-0391852EFO_0004739
DiseaseX-11880 measurement

UGT1A5 UGT1A4

1.37e-0391852EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A5 UGT1A4

1.37e-0391852EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A5 UGT1A4

1.37e-0391852EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A5 UGT1A4

1.37e-0391852EFO_0004570, GO_0009410
DiseaseHermanski-Pudlak Syndrome

DTNBP1 AP3D1

1.70e-03101852C0079504
Diseasebilirubin measurement, response to tenofovir

UGT1A5 UGT1A4

1.70e-03101852EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A5 UGT1A4

1.70e-03101852EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A5 UGT1A4

1.70e-03101852EFO_0802185
DiseaseHermansky-Pudlak syndrome

DTNBP1 AP3D1

1.70e-03101852cv:C0079504
DiseaseX-23974 measurement

UGT1A5 UGT1A4

1.70e-03101852EFO_0800867
Diseaseblood molybdenum measurement

XKR4 SLIT3 ABCG2

1.74e-03381853EFO_0007582
Diseasevaline measurement

GLS2 ACACB ABCG2

2.02e-03401853EFO_0009792
Diseasepregnenetriol sulfate measurement

UGT1A5 UGT1A4

2.07e-03111852EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A5 UGT1A4

2.07e-03111852EFO_0600039
Diseasehistidine betaine (hercynine) measurement

UGT1A5 UGT1A4

2.07e-03111852EFO_0800972
DiseaseX-21796 measurement

UGT1A5 UGT1A4

2.07e-03111852EFO_0800825
DiseaseBardet-Biedl syndrome (implicated_via_orthology)

BBS2 SCAPER

2.07e-03111852DOID:1935 (implicated_via_orthology)
Diseasealdosterone measurement

UGT1A5 UGT1A4

2.07e-03111852EFO_0010219
Diseasebiliverdin measurement

UGT1A5 UGT1A4

2.48e-03121852EFO_0021033
Diseaseasthma

TOB2 MYT1 MUC16 HEATR5A RFC1 NRROS FASLG CSMD3 GLI3 OSBPL7 FBXL20 PCNT

2.90e-0375118512MONDO_0004979
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

DTNBP1 PKHD1

2.91e-03131852EFO_0000707, EFO_0004193, EFO_0007932
Diseasepregnenetriol disulfate measurement

UGT1A5 UGT1A4

2.91e-03131852EFO_0800587
Disease1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement

MYO5B DOCK7

2.91e-03131852EFO_0800413
Diseaseretinol dehydrogenase 16 measurement

UGT1A5 UGT1A4

2.91e-03131852EFO_0802007
DiseaseParoxysmal atrial fibrillation

FRMD4B SLIT3 KCNN2 KCNN3 MYO18B

3.09e-031561855C0235480
Diseasefamilial atrial fibrillation

FRMD4B SLIT3 KCNN2 KCNN3 MYO18B

3.09e-031561855C3468561
DiseasePersistent atrial fibrillation

FRMD4B SLIT3 KCNN2 KCNN3 MYO18B

3.09e-031561855C2585653
DiseaseGastrointestinal Stromal Sarcoma

GLI3 HHAT DISP1

3.21e-03471853C3179349
Diseaselysophosphatidylcholine 15:0 measurement

POU4F2 PKHD1

3.39e-03141852EFO_0020941
Diseasesmoking status measurement, carotid artery intima media thickness

TRIP12 FRMD4B TBC1D8

3.41e-03481853EFO_0006527, EFO_0007117
DiseaseAtrial Fibrillation

FRMD4B SLIT3 KCNN2 KCNN3 MYO18B

3.44e-031601855C0004238
DiseaseGastrointestinal Stromal Tumors

GLI3 HHAT DISP1

3.83e-03501853C0238198
DiseaseTourette syndrome

SGPP2 MUC16 CSMD3

3.83e-03501853EFO_0004895
Diseasebrain ischemia (biomarker_via_orthology)

NAIP FASLG CASP12 PLA2G4A

3.94e-031021854DOID:2316 (biomarker_via_orthology)
Diseasegeneralised epilepsy

GLS2 PADI6 AP3D1

4.28e-03521853EFO_0005917
Diseaseurate measurement

DNAJC13 GLS2 RREB1 FRMD4B TBC1D8 SCAPER PKHD1 TMF1 PLA2G4A ABCG2 MYO18B PC FOXK1

4.40e-0389518513EFO_0004531
DiseaseBlood Platelet Disorders

PLA2G4A AP3D1

4.43e-03161852C0005818
DiseasePre-Eclampsia

EPHX1 CORIN

4.43e-03161852C0032914
Diseasecongestive heart failure (biomarker_via_orthology)

FASLG CASP12 CORIN HSF1

4.67e-031071854DOID:6000 (biomarker_via_orthology)
DiseaseInborn Errors of Metabolism

MYO5B PLA2G4A

5.00e-03171852C0025521
Diseaseheart disease (biomarker_via_orthology)

CASP12 EP300

5.00e-03171852DOID:114 (biomarker_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A5 UGT1A4

5.00e-03171852EFO_0004611, EFO_0007800
DiseaseX-21441 measurement

UGT1A5 UGT1A4

5.00e-03171852EFO_0800814
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR9 TLR6

5.00e-03171852DOID:8677 (biomarker_via_orthology)
Diseaseleukemia

FOXM1 BIRC2 FANCC

5.01e-03551853C0023418
DiseaseDiffuse Large B-Cell Lymphoma

RANGAP1 ABCG2 EP300

5.01e-03551853C0079744
Diseaseangiopoietin-related protein 1 measurement

UGT1A5 UGT1A4

5.60e-03181852EFO_0801382
Diseaseinformation processing speed, response to cranial radiation therapy

FAM171A1 CASP12 SLIT3

5.81e-03581853EFO_0004363, EFO_0010950

Protein segments in the cluster

PeptideGeneStartEntry
FRHMSLLDISSDLAT

NAIP

416

Q13075
HFNSTLMALIRTALD

CACNA1A

1891

O00555
SLLSDSMLHSAINSQ

EP300

526

Q09472
FLRLTAMATHSESNL

EPB42

561

P16452
EGTFAHLSNLRSLML

CPN2

306

P22792
LSSHMYSASLLRLSQ

BUB1

666

O43683
RIESSSNTMHLAFRS

CSMD3

1666

Q7Z407
LTHFGVLMDLSRSTV

ADGRG4

2721

Q8IZF6
MSLSLISTSALENEH

ADGRA3

976

Q8IWK6
QFSAALRLATTMTNH

ABCG2

141

Q9UNQ0
ISLDVLFSTASIMHL

HTR2C

131

P28335
LNMDSLSARRTLHTF

ABHD4

86

Q8TB40
ALATHILSLATEMAA

AKAP11

1201

Q9UKA4
ILSLATEMAASHLDN

AKAP11

1206

Q9UKA4
LDNITISTTAHMAAF

GLCE

391

O94923
FMATNSLHLTTFSLQ

CCNT1

176

O60563
TLFFQISMSLDVASH

CDIPT

91

O14735
SSDSTFLVFMSHSIL

CASP12

161

Q6UXS9
LQHAALSMFVTSFTT

DISP1

601

Q96F81
ALLTRTFTDHVMLFT

DDX27

456

Q96GQ7
VSQMSALLDSAHLLA

AP3D1

456

O14617
RTALMLAVQHNSSSI

ANKRD19P

201

Q9H560
VLALMAHSLATTLSD

CNR2

261

P34972
SFNSNTFLTRLLVHM

RANGAP1

506

P46060
SAAAASRDITLFHAM

MTA2

221

O94776
VMTTQLRHSNLSLVF

IQCH

901

Q86VS3
FLIDTSASMNQRSHL

INTS6

6

Q9UL03
MVHGALSLALSSVRS

PTPN23

1311

Q9H3S7
LLRHSTELFMDSGFS

ACACB

1346

O00763
FSASELMTRLHSSLR

ARHGEF19

196

Q8IW93
HSNVRLLSSLLLTMS

ANAPC7

16

Q9UJX3
LLTATFAHADSALRM

HEY2

226

Q9UBP5
SMALIHNRSLFSDKQ

MCM4

336

P33991
AMTHGFSQLDLSTLT

MUC16

6476

Q8WXI7
HISMSNLTFLARRED

NPHS1

396

O60500
GRAMSFQSIIHLSLD

PADI6

6

Q6TGC4
RFESLTLSHNNMIAL

POU4F1

311

Q01851
STSMSHINLLFSRRA

FAM171A1

356

Q5VUB5
RRSQHTDDSALCMSL

LRCH3

536

Q96II8
VLFFLTMSLATHRST

MDN1

4621

Q9NU22
LHAMDSTRFSSPRLS

GLI3

271

P10071
SSVASATVHIRMAFL

TMBIM4

21

Q9HC24
SKSALLRSFLMNSQH

GNPTAB

731

Q3T906
TLLSAIASALHTSTM

MBD3

176

O95983
MNASSDRVFHESILL

ITPR1

1821

Q14643
LSHNRLSFIKASSMS

LRIG3

81

Q6UXM1
LSFIKASSMSHLQSL

LRIG3

86

Q6UXM1
MLQSSSQLSHSRSRE

KCNH7

251

Q9NS40
RVMLLHSKLFTDASS

KCNN2

271

Q9H2S1
ANMTSLVHLTLSRNT

LRFN1

86

Q9P244
MLTRLVLSAHLSSTT

KCNJ5-AS1

1

Q8TAV5
FSHLESRDLALMVAA

CARMIL3

196

Q8ND23
MFSEQAAQRAHTLLS

POLD2

1

P49005
MLSSHGFSVDTSALL

HSF1

401

Q00613
MSAYLAEQSRLHLSQ

PLXNA1

1831

Q9UIW2
VMLLHSKLFTDASSR

KCNN3

421

Q9UGI6
QSLFMSALSAHPDRS

L3MBTL1

711

Q9Y468
TQLFFIHTLSSMESS

OR51G1

101

Q8NGK1
AFTNALTHTVAMSTL

OR3A2

161

P47893
AFTNALTHTVAMSTL

OR3A3

161

P47888
ALQSRDFHFSMDSLL

PDZD4

321

Q76G19
LESMTANLTHLEASF

DTNBP1

111

Q96EV8
SRNQFSTMSHLRKDS

EBLN2

41

Q6P2I7
MALDSTIAHLSLRNN

LRRC71

216

Q8N4P6
STHFATLTARMLIAL

KRIT1

146

O00522
LSAEAVRNTLSLMHS

GLS2

381

Q9UI32
LVLMLLHTVVSFSSN

NALF2

436

O75949
SASTTMANKRSFQLH

LRIT3

431

Q3SXY7
HTFADVVRLVSNASM

POMGNT2

326

Q8NAT1
TSKFMTTFSQLRELH

LRRC20

66

Q8TCA0
FFHALLHSVMTSRLN

OR12D2

151

P58182
HQSRALAESMLTTSE

GREB1L

576

Q9C091
RMHSATSLFIVNLAV

GPR83

101

Q9NYM4
RLSLSNMHTAQLELT

PCNT

251

O95613
SSSDRMHALSLKIVL

NUP155

1236

O75694
HLSALSTANMARLSA

OLIG3

251

Q7RTU3
SLLHTLLMNSLSFCA

OR1G1

156

P47890
FFHALLHSLMTSRLN

OR12D1

151

P0DN82
RFHAALASCSTSMLI

HHAT

426

Q5VTY9
GTLNSSMLHRSAESL

PRICKLE1

581

Q96MT3
SMLHRSAESLKSLSS

PRICKLE1

586

Q96MT3
RSGSLESQSHLLSEM

FRMD4B

691

Q9Y2L6
SSASNRHMLFTIKDN

CEFIP

846

Q711Q0
RLSALDNLLNHSSMF

HYOU1

821

Q9Y4L1
TEDQLSLASIHYMRS

TTC26

151

A0AVF1
LHLNMALVLSNFSTL

EPHX1

246

P07099
AFMAATDHSDQLRLS

HEATR5A

1271

Q86XA9
SADMADHSNLIRSLL

BBS2

611

Q9BXC9
SSDSTFLVLMSHGIL

CASP5

256

P51878
RMSSHTETSSFLQTL

DOCK7

961

Q96N67
QEALMHTSSDLSRQL

CCDC175

681

P0C221
TSANHLAFTVMELSR

CYP46A1

306

Q9Y6A2
TILTQHLAFRSVSMA

DNAH17

2606

Q9UFH2
LNRTSSDSALHTSVM

CRTC2

166

Q53ET0
MFSAHNLQSVFSRLI

DHX57

1011

Q6P158
LRHLQTFLENITSSM

COL6A5

251

A8TX70
SLSAMRFLTAVNLEH

GSTK1

96

Q9Y2Q3
SATHRTRNTMSLLAA

GRHPR

296

Q9UBQ7
GHLLAMSRSSSLSAQ

FANCC

451

Q00597
LSMGLSSFISRRHLQ

FOXK1

136

P85037
LSQAMLERSAQSHSL

ANKMY1

481

Q9P2S6
LERSAQSHSLLKMAS

ANKMY1

486

Q9P2S6
VQMTFLRLLSASAHQ

COL5A1

1726

P20908
SSLLETMLSQADSLH

CCP110

721

O43303
VNSSSFLMVHRAATE

CORIN

696

Q9Y5Q5
ERFIVLHLSSTMDNS

DTHD1

476

Q6ZMT9
LHLSSTMDNSHLVTF

DTHD1

481

Q6ZMT9
AESMVLSSLLALLHS

DNAJC13

1811

O75165
EFHRTMLNFSSATDL

HASPIN

776

Q8TF76
IALLKFSSHRAAAMA

DND1

181

Q8IYX4
LAASLMSSELARHSK

FOXM1

401

Q08050
MLQSLAALDSRSHTS

FCHSD2

536

O94868
TAMRLESNNTFLLHF

CENPI

546

Q92674
EGLSLAFRHMASSLL

SCAPER

1241

Q9BY12
HTLFSGISDRMLQDT

POLR3E

596

Q9NVU0
DSDLSLSSMVFLNHS

PEX1

1076

O43933
LHQFLRGTSSMSSLH

BVES

306

Q8NE79
NMNASSSRSHLVITI

KIF28P

221

B7ZC32
LFANARNITTLDMSH

NRROS

421

Q86YC3
ATLHTLLMARLSFCA

OR1E3

156

Q8WZA6
HSSLSSVLAALTMER

OSBPL7

311

Q9BZF2
ETLIHNRMNTTLSSL

PLA2G4A

301

P47712
VFSTSSLMLALSRHS

SDHAF2

6

Q9NX18
SFMTESQNLSTHLLI

ABCB8

186

Q9NUT2
NIVALTHTFLMARLS

OR1N1

151

Q8NGS0
ASMNVLSSLLDLHAS

MROH2A

1016

A6NES4
LHMSAAAASRDITLF

MTA3

221

Q9BTC8
AAASRDITLFHAMDT

MTA3

226

Q9BTC8
NVESFASMLRHSPLT

MRPS28

76

Q9Y2Q9
FASTMVHALNTILLT

VAC14

581

Q08AM6
MTDSRTNSFLHILDI

TRDMT1

91

O14717
LTALEMLTAFASHIR

MRPL53

81

Q96EL3
AMITSHLIQLSLSRS

RPP38

141

P78345
ISFPNMASDSRHTLL

TSEN54

301

Q7Z6J9
MATARNLSNLTLAHE

TCP11L2

66

Q8N4U5
VQDLALHMSLRTYSS

RFC1

976

P35251
FRQFLETHSSSMDLM

RGS22

866

Q8NE09
IQLSIFSHRFMSIAE

OPLAH

736

O14841
RFESLTLSHNNMIAL

POU4F2

301

Q12837
RHLDLASCTSITNMS

FBXL20

146

Q96IG2
DRSMSSSLSASQLHT

MED24

876

O75448
KNRHSLEISSALNMF

MYCBP2

3086

O75592
HLSSLTLVGAMRESF

PKHD1

2216

P08F94
SAAAASRDITLFHAM

MTA1

241

Q13330
LSASMASLLEDLSHI

SERTAD1

111

Q9UHV2
LSSVLDHPFMSRNSS

PLK4

256

O00444
VSSIFLNSETIMFLH

RASGRF1

286

Q13972
SSMSHSTTASDQRLL

SPRY3

86

O43610
HAMAATAIAFTLLIS

SGPP2

166

Q8IWX5
SSHLLFSSLFSEERM

ABCA8

1181

O94911
TLRFSISNLSMQTHA

BIRC2

256

Q13490
SFLRNLHSVTGTLMT

AKAP3

336

O75969
SHLSSFAVLMALTSQ

ADGRE3

336

Q9BY15
ALRQIADFMASTSHA

ADD2

86

P35612
FVHARNATVRTAMSL

ASCC3

721

Q8N3C0
HNMFTSVFLLTIISS

CMKLR1

121

Q99788
SHSVCLTRLLMAAAF

CNNM1

356

Q9NRU3
SNMSHLSTLILSYNR

SLIT3

796

O75094
SMFQHRDALRSLTDL

PLPPR4

336

Q7Z2D5
HIENFSTEFLTSSLM

UHRF1BP1L

1281

A0JNW5
STEFLTSSLMNIQHF

UHRF1BP1L

1286

A0JNW5
DSKSSLHLMQTSFQL

TMF1

281

P82094
LHLMQTSFQLLSASA

TMF1

286

P82094
SLRALHGAFSMLETV

SPATA2

81

Q9UM82
NLSFRLTSDLVFHMR

ZNF488

281

Q96MN9
SQVRAFRHTSTLAAM

STAG3

226

Q9UJ98
ATLQSELASFLMDHV

STAG3

831

Q9UJ98
LSSASSLDRHMLVHS

RREB1

106

Q92766
SHTNILMLDSASLAG

TLR9

151

Q9NR96
AEHMNDLSALASVSL

TBC1D8

651

O95759
SASMSSLIGASRILH

SLC12A9

356

Q9BXP2
ERLFSMAHTVALDLA

PXDN

1141

Q92626
RLLTTNSDHMTFLQR

UGT1A5

196

P35504
DVSMLHLLATFLESA

XKR4

301

Q5GH76
SFQLGELRLHLMASS

VPS13C

1966

Q709C8
STDIMLSSASIFHLS

TAAR1

101

Q96RJ0
THFANMRSLIQILDS

SGSM1

1021

Q2NKQ1
AQIISATAFHSSMAL

TEAD4

136

Q15561
DMSFLSELTVLRLSH

TLR6

71

Q9Y2C9
LAELRESTSQMHTAS

FASLG

111

P48023
RTELNLHQMADSSSF

MYO18B

771

Q8IUG5
LINRSFSSHHLSMAS

MYO18B

926

Q8IUG5
LSFSKMTNLLSHQRI

ZNF133

221

P52736
KAFSRSSSLTQHQRM

ZNF264

546

O43296
ADMKLLSSSVHSLLS

ZCCHC14

521

Q8WYQ9
DSQHLDRLSFQSSKM

ZSWIM3

196

Q96MP5
LSSLTSFQTHIRMHS

ZNF69

341

Q9UC07
LSSRANAFSIAALMS

TBX20

11

Q9UMR3
AFLDTFTLLDSQMTH

ZNF304

231

Q9HCX3
AAVRLDFHTMSSTDL

UGT2B28

411

Q9BY64
SVHLEDMATNSRAFT

VEZT

201

Q9HBM0
ASLRALESLMTEFFH

XPO6

6

Q96QU8
MLRQETSLTSHDLFD

TRIP12

1726

Q14669
MSSSTLAHSLAAIEA

ZNF335

181

Q9H4Z2
TFLENFSSMRMLSHL

VPS37C

131

A5D8V6
MDTTFRDAHQSLLAT

PC

566

P11498
KSLSLSMHSLNFITA

TOB2

231

Q14106
RSFHLEASLMDALLN

TRPM4

421

Q8TD43
KAFSRSSSLTQHQRM

ZNF805

546

Q5CZA5
KLLTTNSDHMTFLQR

UGT1A4

196

P22310
LDSILRQLNSFHSVM

MYO5A

1661

Q9Y4I1
FRTSLHLLMETLNAT

MYO5B

636

Q9ULV0
AHMAATAILNLSTRC

MYT1

626

Q01538