Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

MGAT5 MGAT5B

3.64e-0521212GO:0030144
GeneOntologyMolecularFunctionATP hydrolysis activity

PMS2P3 DHX37 DHX40 FIGNL2 CHD4 MORC2 DDX6 MACF1 MORC3 DNAH6 ATP2B2

7.77e-0544112111GO:0016887
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

EPHB3 ERBB2 CAD PDK1 GRK4 OBSCN DGKA PFKP FRK CSF1R PIK3CD MAP3K9 PRKCQ MAP3K21

1.01e-0470912114GO:0016773
GeneOntologyMolecularFunctionkinase activity

EPHB3 ERBB2 CAD PDK1 GRK4 OBSCN DGKA PFKP FRK CSF1R PIK3CD MAP3K9 PRKCQ MAP3K21

2.19e-0476412114GO:0016301
GeneOntologyMolecularFunctionATP-dependent activity

PMS2P3 ATG7 DHX37 DHX40 FIGNL2 CHD4 MORC2 DDX6 MACF1 MORC3 DNAH6 ATP2B2

3.56e-0461412112GO:0140657
GeneOntologyBiologicalProcessregulation of insulin secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

5.96e-062311159GO:0050796
GeneOntologyBiologicalProcessinsulin secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

2.33e-052741159GO:0030073
GeneOntologyBiologicalProcessregulation of peptide hormone secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

2.54e-052771159GO:0090276
GeneOntologyBiologicalProcessregulation of protein secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL PRKCQ ALOX5

2.68e-0535011510GO:0050708
GeneOntologyBiologicalProcessregulation of peptide transport

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

2.92e-052821159GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

2.92e-052821159GO:0002791
GeneOntologyBiologicalProcessregulation of hormone secretion

SFRP1 ATG7 ANO1 FAM3D CRY1 OSBP PPP3CA RPTOR GLUL ALOX5

3.02e-0535511510GO:0046883
GeneOntologyBiologicalProcessprotein autophosphorylation

EPHB3 NLRP12 CAD OBSCN IQGAP1 CSF1R MAP3K9 MAP3K21

4.23e-052281158GO:0046777
GeneOntologyBiologicalProcessneuron development

EPHB3 CFH PRTG ERBB2 SFRP1 ATG7 FIGNL2 PLXND1 CSMD3 PIAS2 EDNRB IQGAP1 PPP3CA DST CSF1R HMCN2 OTOGL MACF1 PRKCQ ATP2B2 SDK1

5.33e-05146311521GO:0048666
GeneOntologyBiologicalProcessprotein secretion

SFRP1 ATG7 ANO1 FAM3D EDNRB OSBP PPP3CA RPTOR GLUL PRKCQ ALOX5

7.81e-0548011511GO:0009306
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

SFRP1 ATG7 ANO1 FAM3D EDNRB OSBP PPP3CA RPTOR GLUL PRKCQ ALOX5

8.25e-0548311511GO:0035592
GeneOntologyBiologicalProcessneuron projection development

EPHB3 PRTG ERBB2 SFRP1 ATG7 FIGNL2 PLXND1 CSMD3 PIAS2 IQGAP1 PPP3CA DST CSF1R HMCN2 OTOGL MACF1 PRKCQ ATP2B2 SDK1

8.62e-05128511519GO:0031175
GeneOntologyBiologicalProcessprotein localization to extracellular region

SFRP1 ATG7 ANO1 FAM3D EDNRB OSBP PPP3CA RPTOR GLUL PRKCQ ALOX5

9.37e-0549011511GO:0071692
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

ERBB2 SFRP1 CAD PIAS2 ATF2 SMYD2 IQGAP1 OSBP CSF1R PIAS3 RPTOR DHPS HPX PRKCQ MORC3 MGAT5B

1.03e-0497611516GO:0018193
GeneOntologyBiologicalProcesspeptide hormone secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

1.07e-043341159GO:0030072
GeneOntologyBiologicalProcessglucose homeostasis

ATG7 ANO1 CRY1 OSBP PPP3CA PRCP RPTOR DHPS ALOX5

1.17e-043381159GO:0042593
GeneOntologyBiologicalProcesscarbohydrate homeostasis

ATG7 ANO1 CRY1 OSBP PPP3CA PRCP RPTOR DHPS ALOX5

1.20e-043391159GO:0033500
GeneOntologyBiologicalProcesshormone secretion

SFRP1 ATG7 ANO1 FAM3D CRY1 OSBP PPP3CA RPTOR GLUL ALOX5

1.23e-0442011510GO:0046879
GeneOntologyBiologicalProcesspeptide secretion

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

1.31e-043431159GO:0002790
GeneOntologyBiologicalProcessregulation of epithelial cell proliferation

ERBB2 SFRP1 IRF6 ATF2 STAT1 EDNRB RGN PIK3CD RPTOR GLUL ALOX5

1.43e-0451411511GO:0050678
GeneOntologyBiologicalProcesshormone transport

SFRP1 ATG7 ANO1 FAM3D CRY1 OSBP PPP3CA RPTOR GLUL ALOX5

1.54e-0443211510GO:0009914
GeneOntologyBiologicalProcesspeptide transport

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR GLUL ALOX5

1.70e-043551159GO:0015833
GeneOntologyBiologicalProcesscell projection morphogenesis

EPHB3 PRTG ERBB2 ATG7 ANO1 PLXND1 PIAS2 IQGAP1 PPP3CA DST CSF1R HMCN2 MACF1 PRKCQ

2.05e-0482611514GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

EPHB3 PRTG ERBB2 ATG7 PLXND1 PIAS2 PPP3CA DST CSF1R HMCN2 MACF1 PRKCQ ATP2B2

2.75e-0474811513GO:0048667
GeneOntologyBiologicalProcessnegative regulation of hormone secretion

SFRP1 FAM3D CRY1 PPP3CA RPTOR

2.80e-041031155GO:0046888
GeneOntologyBiologicalProcessregulation of protein transport

SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR SLC35D3 GLUL PRKCQ ALOX5

2.98e-0456011511GO:0051223
GeneOntologyBiologicalProcessregulation of establishment of protein localization

ERBB2 SFRP1 ATG7 ANO1 FAM3D OSBP PPP3CA RPTOR SLC35D3 GLUL PRKCQ ALOX5

3.85e-0467411512GO:0070201
GeneOntologyBiologicalProcessnegative regulation of insulin secretion

SFRP1 FAM3D PPP3CA RPTOR

3.99e-04621154GO:0046676
GeneOntologyBiologicalProcesswound healing

CFH ERBB2 FIGNL2 DGKA PPP3CA DST PRCP MACF1 PRKCQ ALOX5

4.41e-0449311510GO:0042060
GeneOntologyBiologicalProcessregulation of osteoclast differentiation

SFRP1 PPP3CA CSF1R PIAS3 RPTOR

4.84e-041161155GO:0045670
HumanPhenoArteria lusoria

PLXND1 DDX6 PIK3CD

1.21e-057373HP:0031014
HumanPhenoAbnormal pharynx physiology

NLRP12 CR2

5.13e-052372HP:0033152
HumanPhenoPharyngalgia

NLRP12 CR2

5.13e-052372HP:0033050
HumanPhenoAbnormal subclavian artery morphology

PLXND1 DDX6 PIK3CD

5.59e-0511373HP:0031251
DomainTyr_kinase_cat_dom

EPHB3 ERBB2 FRK CSF1R MAP3K9 MAP3K21

1.63e-05881146IPR020635
DomainTyrKc

EPHB3 ERBB2 FRK CSF1R MAP3K9 MAP3K21

1.63e-05881146SM00219
DomainKinase-like_dom

EPHB3 ERBB2 GRK4 OBSCN PRDM2 FRK DST CSF1R PIK3CD MAP3K9 MACF1 PRKCQ MAP3K21

2.67e-0554211413IPR011009
DomainGlyclTrfase_18

MGAT5 MGAT5B

1.10e-0431142IPR026116
DomainHATPase_c

PDK1 MORC2 MORC3

2.00e-04191143PF02518
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB3 ERBB2 FRK CSF1R MAP3K9 MAP3K21

2.02e-041381146IPR001245
DomainPINIT

PIAS2 PIAS3

2.20e-0441142PS51466
DomainPINIT

PIAS2 PIAS3

2.20e-0441142PF14324
DomainDDT

BAZ2B BAZ2A

2.20e-0441142PF02791
DomainPINIT

PIAS2 PIAS3

2.20e-0441142IPR023321
DomainMLK1/MLK2/MLK4

MAP3K9 MAP3K21

2.20e-0441142IPR016231
DomainMAP3K10

MAP3K9 MAP3K21

2.20e-0441142IPR015785
Domain-

PDK1 MORC2 MORC3

2.34e-042011433.30.565.10
DomainARM-type_fold

MYBBP1A CAND1 PIK3CD RPTOR ZER1 SERAC1 BRAT1 HECTD1 TARBP1

2.34e-043391149IPR016024
DomainHATPase_C

PDK1 MORC2 MORC3

2.72e-04211143IPR003594
DomainPROTEIN_KINASE_TYR

EPHB3 ERBB2 OBSCN FRK CSF1R

3.20e-04971145PS00109
DomainTyr_kinase_AS

EPHB3 ERBB2 OBSCN FRK CSF1R

3.20e-04971145IPR008266
DomainSpectrin

DST SYNE2 MACF1

3.59e-04231143PF00435
DomainACTININ_2

DST SYNE2 MACF1

3.59e-04231143PS00020
DomainACTININ_1

DST SYNE2 MACF1

3.59e-04231143PS00019
DomainActinin_actin-bd_CS

DST SYNE2 MACF1

3.59e-04231143IPR001589
DomainDDT

BAZ2B BAZ2A

3.65e-0451142SM00571
DomainDDT_dom

BAZ2B BAZ2A

3.65e-0451142IPR018501
DomainWHIM2_dom

BAZ2B BAZ2A

3.65e-0451142IPR028941
DomainWSD

BAZ2B BAZ2A

3.65e-0451142PF15613
Domainfn3

EPHB3 PRTG OBSCN FNDC3A PTPRU SDK1

4.78e-041621146PF00041
DomainProtein_kinase_ATP_BS

EPHB3 ERBB2 GRK4 OBSCN FRK CSF1R MAP3K9 PRKCQ MAP3K21

5.28e-043791149IPR017441
DomainDDT

BAZ2B BAZ2A

5.45e-0461142PS50827
Domain-

DST MACF1

5.45e-04611423.90.1290.10
DomainGAR

DST MACF1

5.45e-0461142PS51460
DomainGAS2

DST MACF1

5.45e-0461142PF02187
Domain-

DST MACF1

5.45e-04611423.30.920.20
DomainGAS_dom

DST MACF1

5.45e-0461142IPR003108
DomainGAS2

DST MACF1

5.45e-0461142SM00243
DomainCH

IQGAP1 DST SYNE2 MACF1

6.69e-04651144SM00033
DomainSpectrin_repeat

DST SYNE2 MACF1

7.21e-04291143IPR002017
Domainzf-CW

MORC2 MORC3

7.60e-0471142PF07496
DomainZF_CW

MORC2 MORC3

7.60e-0471142PS51050
Domainzf-MIZ

PIAS2 PIAS3

7.60e-0471142PF02891
DomainPlectin

DST MACF1

7.60e-0471142PF00681
DomainZF_SP_RING

PIAS2 PIAS3

7.60e-0471142PS51044
DomainPlectin_repeat

DST MACF1

7.60e-0471142IPR001101
DomainZnf_CW

MORC2 MORC3

7.60e-0471142IPR011124
DomainPLEC

DST MACF1

7.60e-0471142SM00250
DomainCH

IQGAP1 DST SYNE2 MACF1

8.85e-04701144PF00307
Domain-

IQGAP1 DST SYNE2 MACF1

9.34e-047111441.10.418.10
DomainFN3

EPHB3 PRTG OBSCN FNDC3A PTPRU SDK1

9.59e-041851146SM00060
DomainSPEC

DST SYNE2 MACF1

9.66e-04321143SM00150
DomainSpectrin/alpha-actinin

DST SYNE2 MACF1

9.66e-04321143IPR018159
Domain-

BAZ2B BAZ2A

1.01e-03811423.30.890.10
DomainZnf_MIZ

PIAS2 PIAS3

1.01e-0381142IPR004181
DomainCH

IQGAP1 DST SYNE2 MACF1

1.04e-03731144PS50021
DomainCH-domain

IQGAP1 DST SYNE2 MACF1

1.15e-03751144IPR001715
DomainPkinase_Tyr

EPHB3 ERBB2 FRK CSF1R MAP3K21

1.17e-031291145PF07714
DomainDNA/RNA_helicase_DEAH_CS

DHX37 DHX40 CHD4

1.26e-03351143IPR002464
DomainARM-like

CAND1 RPTOR ZER1 SERAC1 BRAT1 HECTD1 TARBP1

1.35e-032701147IPR011989
DomainFN3

EPHB3 PRTG OBSCN FNDC3A PTPRU SDK1

1.40e-031991146PS50853
DomainDEAH_ATP_HELICASE

DHX37 DHX40 CHD4

1.60e-03381143PS00690
DomainFN3_dom

EPHB3 PRTG OBSCN FNDC3A PTPRU SDK1

1.79e-032091146IPR003961
DomainEF-hand-dom_pair

CAPN12 DGKA STAT1 DST SCN3A MACF1 PLCB2

1.91e-032871147IPR011992
DomainMBD

BAZ2B BAZ2A

1.96e-03111142SM00391
DomainMBD

BAZ2B BAZ2A

1.96e-03111142PS50982
DomainMethyl_CpG_DNA-bd

BAZ2B BAZ2A

1.96e-03111142IPR001739
DomainPeptidase_S9

DPP8 PREP

1.96e-03111142PF00326
DomainMBD

BAZ2B BAZ2A

1.96e-03111142PF01429
DomainDNA-bd_dom

BAZ2B BAZ2A

1.96e-03111142IPR016177
DomainPeptidase_S9

DPP8 PREP

1.96e-03111142IPR001375
DomainPROTEIN_KINASE_ATP

EPHB3 ERBB2 GRK4 OBSCN FRK CSF1R MAP3K9 PRKCQ MAP3K21

2.01e-034591149PS00107
DomainSH3

OBSCN FRK DST MAP3K9 MACF1 MAP3K21

2.11e-032161146PS50002
DomainSH3_domain

OBSCN FRK DST MAP3K9 MACF1 MAP3K21

2.31e-032201146IPR001452
Domain-

CAND1 RPTOR ZER1 SERAC1 BRAT1 HECTD1

2.42e-0322211461.25.10.10
DomainProt_kinase_dom

EPHB3 ERBB2 GRK4 OBSCN FRK CSF1R MAP3K9 PRKCQ MAP3K21

3.07e-034891149IPR000719
DomainHEAT

CAND1 RPTOR BRAT1

3.14e-03481143PF02985
DomainIGc2

PRTG MXRA5 OBSCN CSF1R HMCN2 SDK1

3.21e-032351146SM00408
DomainIg_sub2

PRTG MXRA5 OBSCN CSF1R HMCN2 SDK1

3.21e-032351146IPR003598
DomainPROTEIN_KINASE_DOM

EPHB3 ERBB2 GRK4 OBSCN FRK CSF1R MAP3K9 PRKCQ MAP3K21

3.24e-034931149PS50011
DomainIg-like_fold

EPHB3 PRTG MXRA5 HLA-DMB OBSCN FNDC3A PLXND1 PTPRU CSF1R HMCN2 SDK1

3.93e-0370611411IPR013783
DomainSushi

CFH CR2 CSMD3

3.94e-03521143PF00084
DomainHelicase_C

DHX37 DHX40 CHD4 DDX6

4.19e-031071144PF00271
DomainHELICc

DHX37 DHX40 CHD4 DDX6

4.19e-031071144SM00490
DomainHelicase_C

DHX37 DHX40 CHD4 DDX6

4.33e-031081144IPR001650
DomainCCP

CFH CR2 CSMD3

4.38e-03541143SM00032
DomainHELICASE_CTER

DHX37 DHX40 CHD4 DDX6

4.48e-031091144PS51194
DomainHELICASE_ATP_BIND_1

DHX37 DHX40 CHD4 DDX6

4.48e-031091144PS51192
DomainDEXDc

DHX37 DHX40 CHD4 DDX6

4.48e-031091144SM00487
DomainHelicase_ATP-bd

DHX37 DHX40 CHD4 DDX6

4.63e-031101144IPR014001
DomainDUF1605

DHX37 DHX40

4.73e-03171142IPR011709
DomainOB_NTP_bind

DHX37 DHX40

4.73e-03171142PF07717
DomainSUSHI

CFH CR2 CSMD3

4.85e-03561143PS50923
DomainSushi_SCR_CCP_dom

CFH CR2 CSMD3

5.10e-03571143IPR000436
DomainHATPase_c

PDK1 MORC2

5.30e-03181142SM00387
DomainHA2

DHX37 DHX40

5.30e-03181142SM00847
DomainHA2

DHX37 DHX40

5.30e-03181142PF04408
DomainHelicase-assoc_dom

DHX37 DHX40

5.30e-03181142IPR007502
Domain-

CAPN12 DGKA STAT1 DST MACF1 PLCB2

5.34e-0326111461.10.238.10
DomainHEAT

CAND1 RPTOR BRAT1

5.35e-03581143IPR000357
Domain-

DPP8 PRCP PREP SERAC1

6.10e-0311911443.40.50.1820
DomainAB_hydrolase

DPP8 PRCP PREP SERAC1

6.10e-031191144IPR029058
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CFH CAND1 VPS39 CHD4 PIAS2 STAT1 SMYD2 IQGAP1 PPP3CA DST PIAS3 GLUL MACF1 ZNF565 MORC3 HECTD1 MGAT5B TARBP1 SLX4

1.54e-0712851241935914814
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

POLH ANO1 FREM1 DDX6 APEX2 MACF1 MAP3K21

1.30e-06152124734299191
Pubmed

Inhibition of Stat1-mediated gene activation by PIAS1.

PIAS2 STAT1 PIAS3

1.53e-06712439724754
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYBBP1A CAD DHX37 CHD4 PFKP IQGAP1 DST BAZ2A PREP SYNE2 MACF1 HECTD1

4.08e-066531241222586326
Pubmed

Engagement of immune effector cells by trastuzumab induces HER2/ERBB2 downregulation in cancer cells through STAT1 activation.

ERBB2 STAT1

1.26e-052124224693969
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

1.26e-052124211002341
Pubmed

DOG1 and PKC-θ are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors.

ANO1 PRKCQ

1.26e-052124221358619
Pubmed

Specificity of DOG1 (K9 clone) and protein kinase C theta (clone 27) as immunohistochemical markers of gastrointestinal stromal tumour.

ANO1 PRKCQ

1.26e-052124220716167
Pubmed

Aberrant ALOX5 Activation Correlates with HER2 Status and Mediates Breast Cancer Biological Activities through Multiple Mechanisms.

ERBB2 ALOX5

1.26e-052124233224971
Pubmed

CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5.

CHD4 BAZ2A

1.26e-052124223796711
Pubmed

Loss of branched O-mannosyl glycans in astrocytes accelerates remyelination.

MGAT5 MGAT5B

1.26e-052124223761899
Pubmed

Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy.

ATG7 RPTOR

1.26e-052124234862201
Pubmed

Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression.

CHD4 STAT1

1.26e-052124227414498
Pubmed

HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures.

IQGAP1 HECTD1

1.26e-052124228073378
Pubmed

PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.

ERBB2 ATP2B2

1.26e-052124226729871
Pubmed

IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance.

ERBB2 IQGAP1

1.26e-052124221724847
Pubmed

ErbB2-driven downregulation of the transcription factor Irf6 in breast epithelial cells is required for their 3D growth.

ERBB2 IRF6

1.26e-052124230545388
Pubmed

Transcriptional repression of HER2 by ANO1 Cl- channel inhibition in human breast cancer cells with resistance to trastuzumab.

ERBB2 ANO1

1.26e-052124227838298
Pubmed

Diagnostic significance of DOG-1 and PKC-θ expression and c-Kit/PDGFRA mutations in gastrointestinal stromal tumours.

ANO1 PRKCQ

1.26e-052124223862765
Pubmed

Comparison of the substrate specificities and catalytic properties of the sister N-acetylglucosaminyltransferases, GnT-V and GnT-Vb (IX).

MGAT5 MGAT5B

1.26e-052124219846580
Pubmed

Circadian modulation of glucose utilization via CRY1-mediated repression of Pdk1 expression.

PDK1 CRY1

1.26e-052124238199564
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

OMA1 MYBBP1A FNDC3A CHD4 PIAS2 STAT1 PPP1R10 PIAS3 RPTOR FAM3C MORC3 BRAT1 SLX4 ZFP62 ZNF286A

2.62e-0512031241529180619
Pubmed

Ikaros SUMOylation: switching out of repression.

CHD4 PIAS2 PIAS3

2.90e-0517124315767674
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYBBP1A VPS39 OBSCN DGKA ATF2 STAT1 PRDM2 CD82 PIK3CD MAP3K9 MACF1 ADGRE5 CCDC171 SLX4

3.39e-0510841241411544199
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

3.77e-053124212399109
Pubmed

Alpha-1-antitrypsin suppresses oxidative stress in preeclampsia by inhibiting the p38MAPK signaling pathway: An in vivo and in vitro study.

ATF2 STAT1

3.77e-053124228358847
Pubmed

Gastrointestinal stromal tumors (GISTs): CD117, DOG-1 and PKCθ expression. Is there any advantage in using several markers?

ANO1 PRKCQ

3.77e-053124222197035
Pubmed

A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle.

EDNRB PRKCQ

3.77e-05312421508194
Pubmed

Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.

CFH CR2

3.77e-053124219828624
Pubmed

Diagnostic relevance of overexpressions of PKC-θ and DOG-1 and KIT/PDGFRA gene mutations in extragastrointestinal stromal tumors: a Korean six-centers study of 28 cases.

ANO1 PRKCQ

3.77e-053124222399613
Pubmed

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.

IQGAP1 OSBP

3.77e-053124226473364
Pubmed

PIAS genes as disease markers in bipolar disorder.

PIAS2 PIAS3

3.77e-053124230861611
Pubmed

Dysregulation of the renin-angiotensin system during lung ischemia-reperfusion injury.

PRCP PREP

3.77e-053124227437782
Pubmed

USP14 Regulates ATF2/PIK3CD Axis to Promote Microvascular Endothelial Cell Proliferation, Migration, and Angiogenesis in Diabetic Retinopathy.

ATF2 PIK3CD

3.77e-053124236939972
Pubmed

SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.

PIAS2 STAT1

3.77e-053124212764129
Pubmed

Essential role for autophagy in the maintenance of immunological memory against influenza infection.

ATG7 ALOX5

3.77e-053124224747745
Pubmed

A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins.

PIAS2 ATF2

3.77e-05312429920921
Pubmed

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

PIAS2 PIAS3

3.77e-053124212077349
Pubmed

The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.

ERBB2 ATP2B2

3.77e-053124228235801
Pubmed

Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression.

ATG7 STAT1

3.77e-053124236300763
Pubmed

The Potential Role of BRCA1-Associated ATM Activator-1 (BRAT1) in Regulation of mTOR.

RPTOR BRAT1

3.77e-053124225657994
Pubmed

A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.

CFH CR2

3.77e-05312423782802
Pubmed

DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells.

ERBB2 DDX6

3.77e-053124229987267
Pubmed

Regulation of the Ca2+-activated chloride channel Anoctamin-1 (TMEM16A) by Ca2+-induced interaction with FKBP12 and calcineurin.

ANO1 PPP3CA

3.77e-053124232422433
Pubmed

Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.

BAZ2B BAZ2A

3.77e-053124228341809
Pubmed

Developmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-V.

MGAT5 MGAT5B

3.77e-053124222715095
Pubmed

Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry.

PRCP PREP

3.77e-053124223392115
Pubmed

HIV-1 gp120 influences the expression of microRNAs in human monocyte-derived dendritic cells via STAT3 activation.

STAT1 PIAS3

3.77e-053124226116514
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ERBB2 DPP8 PFKP DDX6 DST RPTOR SYNE2 MAP3K9 MACF1 MORC3 MAP3K21 HECTD1

6.20e-058611241236931259
Pubmed

Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis.

CAND1 POLH SLX4

6.48e-0522124322902628
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BAZ2B DHX37 POLH CHD4 MORC2 PIAS2 PRDM2 PPP1R10 BAZ2A MORC3

6.79e-056081241036089195
Pubmed

A conserved role of IQGAP1 in regulating TOR complex 1.

IQGAP1 RPTOR

7.53e-054124222328503
Pubmed

Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR.

ERBB2 CD82

7.53e-054124214576349
Pubmed

Cloning, expression, and initial characterization of a novel cytokine-like gene family.

FAM3D FAM3C

7.53e-054124212160727
Pubmed

DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.

PIAS2 PIAS3

7.53e-054124211477070
Pubmed

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence.

ATG7 DHPS

7.53e-054124231474573
Pubmed

N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways.

MGAT5 MGAT5B

7.53e-054124214561752
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1

7.53e-05412428954775
Pubmed

The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression.

ERBB2 DST

7.53e-054124211375975
Pubmed

N-linked polylactosamine glycan synthesis is regulated by co-expression of β3GnT2 and GCNT2.

MGAT5 MGAT5B

7.53e-054124224105809
Pubmed

PIAS proteins promote SUMO-1 conjugation to STAT1.

STAT1 PIAS3

7.53e-054124212855578
Pubmed

STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3.

ERBB2 STAT1

7.53e-054124222693070
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYBBP1A CAD POLH CHD4 IQGAP1 ATP2B2

9.01e-05202124624639526
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

DHX37 PLXND1 DST MACF1 HECTD1

1.07e-04130124512421765
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

ERBB2 OBSCN FNDC3A CHD4 CRY1 PREP ZER1

1.14e-04304124732235678
Pubmed

Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.

MORC2 BAZ2A MACF1

1.22e-0427124319026994
Pubmed

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

PDK1 RPTOR

1.25e-045124212150926
Pubmed

Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1.

CFH CR2

1.25e-04512429799332
Pubmed

The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis.

PDK1 RPTOR

1.25e-045124234646383
Pubmed

The CW domain, a structural module shared amongst vertebrates, vertebrate-infecting parasites and higher plants.

MORC2 MORC3

1.25e-045124214607086
Pubmed

Physical and genetic maps of the deafwaddler region on distal mouse Chr 6.

SLC6A11 ATP2B2

1.25e-04512429615221
Pubmed

Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.

CFH CR2

1.25e-045124220962256
Pubmed

PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.

PIAS2 PIAS3

1.25e-045124215907835
Pubmed

Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system.

ERBB2 CSF1R

1.25e-04512421334406
Pubmed

Expression and prognostic assessment of dipeptidyl peptidase IV and related enzymes in B-cell chronic lymphocytic leukemia.

DPP8 PREP

1.25e-045124220534982
Pubmed

Functional CSF-1 receptors are located at the nuclear envelope and activated via the p110δ isoform of PI 3-kinase.

CSF1R PIK3CD

1.25e-045124222084313
Pubmed

A novel family of bromodomain genes.

BAZ2B BAZ2A

1.25e-045124210662543
Pubmed

SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death.

PIAS2 PIAS3

1.25e-045124228622293
Pubmed

Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1.

ATG7 CRY1

1.25e-045124229937374
Pubmed

SUMO Modification Reverses Inhibitory Effects of Smad Nuclear Interacting Protein-1 in TGF-β Responses.

PIAS2 PIAS3

1.25e-045124227703003
Pubmed

The role of STAT transcription factors in apoptosis regulation of hypothalamic neurons in aging in HER-2/neu transgenic mice and wild-type FVB/N mice.

ERBB2 STAT1

1.25e-045124227417725
Pubmed

The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning.

PPP3CA SLC17A7 NMBR

1.51e-0429124318077674
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

VPS39 FNDC3A DST SYNE2 MACF1 ZNF286A

1.62e-04225124612168954
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

CAND1 CHD4 PPP3CA DST SYNE2 MACF1 HECTD1

1.63e-04322124726514267
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYBBP1A CAD CAND1 PDK1 PFKP DDX6 IQGAP1 PPP3CA DST RPTOR GLUL SLC17A7 MACF1 DNAH6 ATP2B2

1.81e-0414311241537142655
Pubmed

Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner.

PIAS2 PIAS3

1.87e-046124216029420
Pubmed

SUMOylation of RORalpha potentiates transcriptional activation function.

PIAS2 PIAS3

1.87e-046124219041634
Pubmed

Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney.

PRCP PREP

1.87e-046124227649628
Pubmed

Novel lethal mouse mutants produced in balancer chromosome screens.

ERBB2 FREM1

1.87e-046124216466971
Pubmed

The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules.

HLA-DMB CD82

1.87e-04612429759843
Pubmed

Neuromedin B and its receptor silencing suppresses osteoclast generation by modulating precursor proliferation via M-CSF/c-Fms/D-type cyclins.

CSF1R NMBR

1.87e-046124228780306
Pubmed

A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis.

PIAS2 PIAS3

1.87e-046124223704280
Pubmed

In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration.

BAZ2B BAZ2A

1.87e-046124235090595
Pubmed

CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.

CR2 CD82

1.87e-04612429804823
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

MYBBP1A CHD4 PFKP IQGAP1

1.88e-0479124426446488
Pubmed

Murine txk: a protein tyrosine kinase gene regulated by T cell activation.

EPHB3 FRK CSF1R

2.03e-043212437542761
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

MYBBP1A CAD CAND1 DDX6 IQGAP1 RPTOR DHPS GLUL HECTD1

2.17e-04571124937167062
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CAD CAND1 DHX37 PFKP STAT1 PPP3CA DST PRCP PREP SYNE2 MACF1 FAM3C BRAT1 HECTD1

2.24e-0412971241433545068
Pubmed

The protein tyrosine kinase family of the human genome.

EPHB3 ERBB2 FRK CSF1R

2.28e-0483124411114734
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ERBB2 MYBBP1A CAD FNDC3A STAT1 DDX6 IQGAP1 DST MACF1 MAP3K21

2.34e-047081241039231216
GeneFamilyFibronectin type III domain containing

EPHB3 PRTG OBSCN FNDC3A PTPRU SDK1

1.57e-04160916555
GeneFamilyZinc fingers MIZ-type

PIAS2 PIAS3

5.18e-04791285
GeneFamilyZinc fingers CW-type

MORC2 MORC3

5.18e-04791296
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

6.88e-048912939
GeneFamilyMannosyl-glycoprotein N-acetylglucosaminyltransferases

MGAT5 MGAT5B

8.82e-049912435
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PRTG MXRA5 OBSCN HMCN2 SDK1

1.32e-03161915593
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

BAZ2B BAZ2A

1.34e-03119121025
GeneFamilyDEAH-box helicases

DHX37 DHX40

2.87e-0316912500
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFH CR2 CSMD3

2.97e-03579131179
CoexpressionGSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN

MYBBP1A CAD CAND1 MORC2 SMYD2 CRY1 OSBP CD82

4.97e-061991248M6932
CoexpressionGSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP

RAMP1 DGKA GASK1B PPP3CA CSF1R PRCP SYNE2 ADGRE5

5.16e-062001248M7234
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_SMG_BASAL_CELL

CFH SFRP1 ANO1 DGKA PFKP CD82 DST KIAA0825 KLHL13 ZNF565

1.37e-0538012410M45714
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ2B APOBEC3H CR2 STAT1 DDX6 IQGAP1 PPP1R10 MACF1

4.53e-081821248eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ2B APOBEC3H CR2 DDX6 IQGAP1 PPP1R10 MACF1

8.28e-07183124728cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ2B APOBEC3H CR2 DDX6 IQGAP1 PPP1R10 MACF1

8.28e-0718312473fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH HLA-DMB BAZ2B CR2 IQGAP1 HPX MACF1

9.57e-071871247b51af2824e65734f333b1325117f4a2e88b17c23
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SHFL IRF6 PLXND1 PTPRU EDNRB CD82

1.03e-0618912471137583e21d874c201c20581ba1995e2bfa3de59
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB BAZ2B APOBEC3H CR2 DDX6 IQGAP1 MACF1

1.06e-061901247ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ERBB2 MXRA5 CD82 SCN3A MAP3K21 SDK1

1.14e-0619212470bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellCOVID-19|World / Disease, condition lineage and cell class

CHD4 STAT1 PRDM2 DDX6 IQGAP1 SYNE2 MACF1

1.50e-0620012477dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HLA-DMB CR2 MGAT5 PIK3CD SCN3A MACF1

5.61e-0615912462881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFRP1 PLXND1 DST SYNE2 FAM3C ATP2B2

7.18e-0616612467a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFRP1 PLXND1 DST SYNE2 FAM3C ATP2B2

7.18e-061661246bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HLA-DMB IRF6 PRDM2 DDX6 MGAT5 MACF1

7.95e-061691246c3a6179a64589a370108fea809b157839347759c
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

CFH ANO1 ASB15 HMCN2 HPX ATP2B2

8.51e-061711246c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB CR2 PRDM2 MGAT5 SCN3A FAM3C

8.80e-06172124662ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP1 PFKP GASK1B FREM1 CRY1 CLUL1

9.39e-0617412469d22a554617a93701d0945de63cc3e7b24322c40
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH PRTG MXRA5 OBSCN CSMD3 EDNRB

9.39e-061741246f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB CR2 PRDM2 RGN CD82 ALOX5

1.07e-051781246be1d991c5a0a5be22f14f57d34ee1330f1a12963
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SFRP1 IRF6 PLXND1 SLC6A11 FAM3C ATP2B2

1.07e-0517812469f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRTG MXRA5 FREM1 SCN3A MAP3K21 SDK1

1.14e-051801246788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MXRA5 SFRP1 ANO1 SLC6A11 HMCN2 SDK1

1.18e-051811246154d5e586cab25155c6d06dfe6ae01203b88e0fb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PFKP IQGAP1 DST KLHL13 HECTD1 DNAH6

1.21e-051821246a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD4 DDX6 PPP1R10 SLC35D3 MACF1 PRKCQ

1.21e-051821246e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD4 DDX6 PPP1R10 SLC35D3 MACF1 PRKCQ

1.21e-0518212461710eab3037a87609d21838be2d2d29c3bc36651
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

CFH IRF6 PTPRU CYP4Z2P DENND2C SDK1

1.21e-051821246caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDK1 OBSCN DGKA DDX6 SYNE2 PRKCQ

1.29e-0518412465350b58aa9979631228835d11eb45ddf81d08bff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP1 PFKP DST KLHL13 SCN3A HECTD1

1.41e-05187124677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH HLA-DMB CR2 IQGAP1 HPX MACF1

1.41e-0518712463ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP1 PFKP DST KLHL13 SCN3A HECTD1

1.41e-051871246f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

ANO1 HMCN2 SCN3A MACF1 ADGRE5 SDK1

1.46e-05188124634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RAMP1 HLA-DMB DST CSF1R PRCP ALOX5

1.46e-0518812469fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RAMP1 HLA-DMB DST CSF1R PRCP ALOX5

1.46e-0518812465e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB CD82 MGAT5 SCN3A FAM3C ALOX5

1.50e-051891246886dceacf96e2b6750c146a381da0bf96a2bb15b
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ANO1 HMCN2 SCN3A MACF1 ADGRE5 SDK1

1.50e-0518912466b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP1 PFKP DST KLHL13 SCN3A HECTD1

1.50e-051891246e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB CD82 MGAT5 SCN3A FAM3C ALOX5

1.50e-0518912465f1f4321939877374a8ee13de93f2d1390af8e2e
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH IRF6 PLXND1 PTPRU EDNRB CD82

1.55e-0519012467068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CAPN12 RGN DST SCN3A HPX ATP2B2

1.55e-051901246b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellfacs-MAT-Fat-3m-Lymphocytic-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB APOBEC3H DGKA CR2 PIK3CD PRKCQ

1.59e-051911246530469909ab0994bece37945e9098359077b0824
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DMB CR2 PRDM2 MGAT5 SCN3A ALOX5

1.59e-05191124684452125d1b5b76974e3f9126f611eff16d45c25
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SFRP1 IRF6 PLXND1 DST FAM3C ATP2B2

1.59e-0519112466e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SFRP1 IRF6 PLXND1 DST FAM3C ATP2B2

1.59e-051911246482db995930346be69072ace2fd78fd453e97fb5
ToppCellfacs-MAT-Fat-3m-Lymphocytic|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB APOBEC3H DGKA CR2 PIK3CD PRKCQ

1.59e-051911246f7a81acb938ce5d383326840dd45f7dd2cf12b1d
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFH ANO1 FREM1 DST MACF1 SDK1

1.59e-0519112466688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SFRP1 RAMP1 ANO1 FREM1 CD82 PRKCQ

1.64e-0519212468ad6678df89175c5a4a835c8566f1552df3c996e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ERBB2 MXRA5 STAT1 CD82 MAP3K21

1.64e-0519212469e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ERBB2 MXRA5 STAT1 CD82 MAP3K21

1.64e-0519212463d777d07878269b87ec7e1f06489cae7c989d633
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFH ANO1 FREM1 DST MACF1 SDK1

1.64e-05192124699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3A IQGAP1 CRY1 MACF1 ADGRE5 ALOX5

1.64e-0519212468b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ERBB2 MXRA5 STAT1 CD82 MAP3K21

1.64e-051921246d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SFRP1 RAMP1 ANO1 FREM1 CD82 PRKCQ

1.64e-0519212462f5378ea0b2fb2f672a36585d375f675983363a1
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH DDX6 DST CSF1R GLUL MACF1

1.69e-05193124606b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH DDX6 DST CSF1R GLUL MACF1

1.69e-0519312469c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH DDX6 DST CSF1R GLUL MACF1

1.69e-051931246a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

PRTG MXRA5 PFKP FREM1 MAP3K21 SDK1

1.69e-051931246738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH DDX6 DST CSF1R GLUL MACF1

1.69e-051931246b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ERBB2 MXRA5 STAT1 CD82 MAP3K21

1.69e-0519312465da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

OBSCN DGKA DDX6 SYNE2 MACF1 PRKCQ

1.79e-0519512464bdedd924564a260841a9153604026b57487c83d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP12 CSF1R PIK3CD ADGRE5 PLCB2 ALOX5

1.79e-05195124610ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

NLRP12 GASK1B CSF1R PIK3CD PLCB2 ALOX5

1.85e-051961246cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

NLRP12 CSF1R PIK3CD GLUL PLCB2 ALOX5

1.90e-051971246a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

CFH MXRA5 SFRP1 IRF6 DST SYNE2

1.90e-05197124624360b660000bdfb999d58fbf4e29585a97e1785
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP12 ATG7 HLA-DMB CSF1R PLCB2 ALOX5

1.90e-0519712461eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCellILEUM-non-inflamed-(8)_Fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CFH MXRA5 SFRP1 GASK1B EDNRB DST

2.01e-051991246d9d7f36b4b5592b7855448730044c90997b55499
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLXND1 GASK1B IQGAP1 CSF1R GLUL ALOX5

2.01e-051991246994e885b8d1874006302a081d13f1ee881d64612
ToppCellILEUM-inflamed-(8)_Fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CFH MXRA5 SFRP1 GASK1B EDNRB DST

2.01e-0519912463a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLXND1 GASK1B IQGAP1 CSF1R GLUL ALOX5

2.01e-051991246f965eb89d6d023c83154276b8fded490fd89c100
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

BAZ2B PPP3CA DST PRCP SYNE2 MACF1

2.07e-052001246dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

BAZ2B DST KIAA0825 PRCP SYNE2 MACF1

2.07e-052001246a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB CR2 PRDM2 MGAT5 SCN3A FAM3C

2.07e-052001246222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFH ERBB2 DST SYNE2 DENND2C HECTD1

2.07e-052001246ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellmild-B_naive|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB CR2 PRDM2 MGAT5 SCN3A FAM3C

2.07e-052001246d0467cab6a42bf780aa49046bf3231ca161dc144
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CR2 OTOGL SLC35D3 NMBR

3.90e-05681244cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b|Hippocampus / BrainAtlas - Mouse McCarroll V32

CR2 OTOGL SLC35D3 NMBR

3.90e-05681244c25fb921dc83eecdc337353894829ae6b5192353
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CR2 OTOGL SLC35D3 NMBR

3.90e-05681244712f5f4d3a1e0c0db1a340332876206b93bdac31
ToppCellCerebellum-Macroglia-ASTROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

EPHB3 FREM1 EDNRB PPP1R3C SLC6A11

6.51e-05151124571841d2001200d1595c85c2b007ee20791a72927
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1|Cerebellum / BrainAtlas - Mouse McCarroll V32

EPHB3 FREM1 EDNRB PPP1R3C SLC6A11

6.51e-05151124560aced0c1cc6b509b73308d03d58a3c44d712ef4
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

CRY1 SLC6A11 SYNE2 MACF1 ADGRE5

7.59e-0515612451545169694f686d28648a68b552c2ae606599d66
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRTG SLC35D3 SERAC1 PLCB2 ALOX5

8.55e-0516012456393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRTG SLC35D3 SERAC1 PLCB2 ALOX5

8.55e-0516012452065938e944eb99478fd8132c2c03adeaee6d447
ToppCelldroplet-Heart-nan-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH PLXND1 GASK1B STAT1 CD82

8.81e-051611245eb546d5065ac506405d240f9a1f55f2122d0c368
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

HLA-DMB CSF1R PIK3CD PLCB2 ALOX5

9.07e-05162124560d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

HLA-DMB CSF1R PIK3CD PLCB2 ALOX5

9.07e-05162124518e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellE18.5-samps-Myeloid-Macrophage|E18.5-samps / Age Group, Lineage, Cell class and subclass

HLA-DMB CSF1R PIK3CD PLCB2 ALOX5

9.07e-0516212450970e4eda60e3f015335e2726e6d565fb2f43372
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP1 DST KLHL13 HECTD1 DNAH6

9.07e-051621245373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH ANO1 FAM3D SLC6A11 CLUL1

9.33e-051631245a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH ANO1 FAM3D SLC6A11 CLUL1

9.33e-051631245454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH ANO1 FAM3D SLC6A11 CLUL1

9.33e-051631245d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH ANO1 FAM3D SLC6A11 CLUL1

9.33e-051631245f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH ANO1 FAM3D SLC6A11 CLUL1

9.33e-051631245d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB CHD4 PRDM2 PPP3CA ALOX5

9.33e-0516312456bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH ANO1 FAM3D SLC6A11 CLUL1

9.33e-051631245be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB APOBEC3H CR2 IQGAP1 ADGRF4

9.61e-05164124507d9252b267cb61c6050fbfa5b440aef1349f673
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB APOBEC3H CR2 IQGAP1 ADGRF4

9.61e-0516412457c016236f0cea38195c1373ebbd2c0b2b2ec81ad
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH SFRP1 EDNRB SLC6A11 SLC17A7

9.61e-05164124501a7c335897128d3478b8b9b44fb461cab493084
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

CAPN12 ERBB2 RAMP1 OSBP KIAA0825

1.05e-041671245f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SFRP1 OBSCN IRF6 OTOGL

1.05e-041671245a4a795751644b22af616335379e64ae95175180c
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Fos_(Layer_5,_medial_posterior_cortex_(Retrosplenial_cortex_(RSG),_subiculum))-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

POLH STYX ADGRF4 TARBP1

1.07e-04881244a909ea58f17716de9cf2486e648b89298b96e0d1
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Fos_(Layer_5,_medial_posterior_cortex_(Retrosplenial_cortex_(RSG),_subiculum))|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

POLH STYX ADGRF4 TARBP1

1.07e-04881244e38bee67177403cc06714b98e824a17055204586
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

EPHB3 MXRA5 SFRP1 DST ADGRF4

1.08e-04168124548089fa2d4a0f31a72405717119b767a92571f01
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFH ERBB2 IRF6 ADGRF4 SDK1

1.11e-041691245aec97583b23112060437b619cb429dc32f29285f
DiseaseRenal Cell Carcinoma

NLRP12 ERBB2 ASB15 CSMD3 SYNE2 ALOX5

1.51e-051281216C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

NLRP12 ERBB2 ASB15 CSMD3 SYNE2 ALOX5

1.51e-051281216C1266043
DiseaseChromophobe Renal Cell Carcinoma

NLRP12 ERBB2 ASB15 CSMD3 SYNE2 ALOX5

1.51e-051281216C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

NLRP12 ERBB2 ASB15 CSMD3 SYNE2 ALOX5

1.51e-051281216C1266044
DiseasePapillary Renal Cell Carcinoma

NLRP12 ERBB2 ASB15 CSMD3 SYNE2 ALOX5

1.51e-051281216C1306837
Diseaseeukaryotic translation initiation factor 1A, X-chromosomal measurement

CFH NLRP12

1.67e-0521212EFO_0801589
Diseasedocking protein 2 measurement

CFH NLRP12

1.67e-0521212EFO_0801543
Diseaseeukaryotic initiation factor 4a-III measurement

CFH NLRP12

1.67e-0521212EFO_0020366
DiseasepolyUbiquitin K48-linked measurement

CFH NLRP12

1.67e-0521212EFO_0022007
Diseasebeta-defensin 128 measurement

CFH NLRP12

1.67e-0521212EFO_0801420
Diseasebromodomain-containing protein 1 measurement

CFH NLRP12

1.67e-0521212EFO_0801431
Diseaseubiquitin-conjugating enzyme E2 N measurement

CFH NLRP12

1.67e-0521212EFO_0020841
Diseasetyrosine-protein kinase CSK measurement

CFH NLRP12

1.67e-0521212EFO_0020820
Diseasetyrosine-protein kinase FYN measurement

CFH SPDYC

1.67e-0521212EFO_0020823
Diseasetyrosine-protein kinase BTK measurement

CFH NLRP12

1.67e-0521212EFO_0020819
Diseasesumo-conjugating enzyme UBC9 measurement

CFH NLRP12

1.67e-0521212EFO_0020757
Diseaseregulatory factor X-associated protein measurement

CFH NLRP12

1.67e-0521212EFO_0801999
Diseasetransforming growth factor beta-3 measurement

CFH NLRP12

1.67e-0521212EFO_0020782
Diseasetroponin i, cardiac muscle measurement

CFH NLRP12

1.67e-0521212EFO_0020788
Diseaseprobable RNA-binding protein 23 measurement

CFH NLRP12

1.67e-0521212EFO_0801917
Diseasevery long-chain acyl-CoA synthetase measurement

NLRP12 PFKP

1.67e-0521212EFO_0802211
Diseasevacuolar protein sorting-associated protein 4B measurement

CFH NLRP12

1.67e-0521212EFO_0802209
Diseasepoly(rC)-binding protein 1 measurement

CFH NLRP12

1.67e-0521212EFO_0801894
Diseaseprotein kinase c beta type (splice variant beta-II) measurement

CFH NLRP12

1.67e-0521212EFO_0020678
Diseaseubiquitin-conjugating enzyme E2 D4 measurement

CFH NLRP12

1.67e-0521212EFO_0802181
Diseasethymocyte nuclear protein 1 measurement

CFH NLRP12

1.67e-0521212EFO_0802132
Diseaseselenide, water dikinase 1 measurement

CFH NLRP12

1.67e-0521212EFO_0802045
Diseaseimmunoglobulin superfamily DCC subclass member 3 measurement

CFH NLRP12

1.67e-0521212EFO_0801689
Diseasehigh mobility group protein B1 measurement

CFH NLRP12

1.67e-0521212EFO_0020449
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

NLRP12 ERBB2 ASB15 CSMD3 SYNE2 ALOX5

3.44e-051481216C0279702
DiseaseMalignant neoplasm of breast

ERBB2 SFRP1 VPS39 POLH OBSCN ATF2 STAT1 EDNRB CSF1R OTOGL SYNE2 MACF1 ADGRF4 CLUL1 NMBR

3.48e-05107412115C0006142
Diseaseezrin measurement

NLRP12 SPDYC

4.99e-0531212EFO_0801597
DiseaseDNA/RNA-binding protein KIN17 measurement

CFH NLRP12

4.99e-0531212EFO_0801536
Diseaseeukaryotic translation initiation factor 5A-1 measurement

CFH NLRP12

4.99e-0531212EFO_0020370
Diseaseephrin type-a receptor 5 measurement

CFH NLRP12

4.99e-0531212EFO_0020353
Diseasesmall ubiquitin-related modifier 3 measurement

CFH NLRP12

4.99e-0531212EFO_0022025
DiseaseB melanoma antigen 2 measurement

CFH NLRP12

4.99e-0531212EFO_0801401
DiseasecAMP-regulated phosphoprotein 19 measurement

CFH NLRP12

4.99e-0531212EFO_0020223
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 4 measurement

CFH NLRP12

4.99e-0531212EFO_0020124
Disease2'-5'-oligoadenylate synthase 1 measurement

CFH NLRP12

4.99e-0531212EFO_0021911
Diseaseprefoldin subunit 5 measurement

CFH NLRP12

4.99e-0531212EFO_0020652
Diseasepolyadenylate-binding protein 4 measurement

CFH NLRP12

4.99e-0531212EFO_0801897
Diseasepolycomb protein SCMH1 measurement

CFH NLRP12

4.99e-0531212EFO_0801898
Diseaseneutrophil cytosol factor 2 measurement

CFH NLRP12

4.99e-0531212EFO_0801837
Diseasenuclear RNA export factor 1 measurement

CFH NLRP12

4.99e-0531212EFO_0801855
Diseasen-terminal Xaa-Pro-Lys N-methyltransferase 1 measurement

CFH NLRP12

4.99e-0531212EFO_0801820
DiseaseNAD kinase measurement

CFH NLRP12

4.99e-0531212EFO_0801821
Diseasetoll-interacting protein measurement

CFH NLRP12

4.99e-0531212EFO_0802133
Diseaseinterleukin-16 measurement

CFH NLRP12

4.99e-0531212EFO_0801717
Diseasesperm-associated antigen 11A measurement

CFH NLRP12

4.99e-0531212EFO_0802082
Diseaseserine-rich single-pass membrane protein 1 measurement

CFH NLRP12

4.99e-0531212EFO_0802056
DiseaseRNA-binding protein 3 measurement

CFH NLRP12

4.99e-0531212EFO_0802031
Diseaserho GTPase-activating protein 25 measurement

CFH NLRP12

4.99e-0531212EFO_0802011
Diseaseretinoid-binding protein 7 measurement

CFH NLRP12

4.99e-0531212EFO_0802006
Diseaseglucose-6-phosphate isomerase measurement

CFH NLRP12

4.99e-0531212EFO_0020407
Diseasehigh mobility group protein B2 measurement

CFH NLRP12

4.99e-0531212EFO_0801676
Diseaseinhibitor of growth protein 1 measurement

CFH NLRP12

4.99e-0531212EFO_0020471
Diseasealdose reductase measurement

CFH NLRP12

9.95e-0541212EFO_0801364
Diseasealpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 measurement

CFH NLRP12

9.95e-0541212EFO_0801374
Diseaseclathrin interactor 1 measurement

NLRP12 SPDYC

9.95e-0541212EFO_0801478
Diseaseacylphosphatase-2 measurement

CFH NLRP12

9.95e-0541212EFO_0801344
Diseasecaspase-8 measurement

CFH NLRP12

9.95e-0541212EFO_0010764
Diseaseubiquitin-fold modifier-conjugating enzyme 1 measurement

CFH NLRP12

9.95e-0541212EFO_0020843
Diseasetyrosine-protein phosphatase non-receptor type 11 measurement

NLRP12 SPDYC

9.95e-0541212EFO_0020835
Diseasetoll-like receptor 2 measurement

CFH HPX

9.95e-0541212EFO_0020777
Diseaseprobable ATP-dependent RNA helicase DDX58 measurement

CFH NLRP12

9.95e-0541212EFO_0801913
Diseasezinc finger protein 18 measurement

CFH NLRP12

9.95e-0541212EFO_0802226
Diseaselymphopenia (implicated_via_orthology)

EDNRB CSF1R

9.95e-0541212DOID:614 (implicated_via_orthology)
Diseaseuncharacterized protein KIAA0040 measurement

CFH NLRP12

9.95e-0541212EFO_0802196
Diseaseurea transporter 2 measurement

CFH NLRP12

9.95e-0541212EFO_0802203
Diseaseadhesion G protein-coupled receptor E2 measurement

CFH ADGRE5

9.95e-0541212EFO_0021892
Diseaseintegral membrane protein 2A measurement

CFH NLRP12

9.95e-0541212EFO_0801704
Diseaseretinoic acid receptor responder protein 3 measurement

NLRP12 PFKP

9.95e-0541212EFO_0802005
DiseaseCUB and Sushi domain-containing protein 2 measurement

CFH NLRP12

9.95e-0541212EFO_0803314
Diseasecolon adenocarcinoma (is_implicated_in)

CHD4 STAT1 CSF1R

1.63e-04261213DOID:234 (is_implicated_in)
Diseasechymotrypsin-like protease CTRL-1 measurement

CFH NLRP12

1.65e-0451212EFO_0801476
Diseaseserine/threonine-protein kinase 17B measurement

CFH NLRP12

1.65e-0451212EFO_0008281
Diseaseprotein fam107a measurement

CFH NLRP12

1.65e-0451212EFO_0020673
Diseasen-acetyltransferase 14 measurement

CFH NLRP12

1.65e-0451212EFO_0801819
Diseaselysophosphatidylcholine acyltransferase 2 measurement

CFH NLRP12

1.65e-0451212EFO_0801775
Diseaselow-density lipoprotein receptor-related protein 1B measurement

CFH NLRP12

1.65e-0451212EFO_0021873
Diseasee3 ubiquitin-protein ligase RNF43 measurement

CFH HPX

1.65e-0451212EFO_0021886
DiseaseSH3 domain-binding protein 2 measurement

CFH NLRP12

1.65e-0451212EFO_0802063
Diseasehigh mobility group protein B3 measurement

CFH NLRP12

1.65e-0451212EFO_0801677
Diseasegeneral transcription factor II-I measurement

CFH NLRP12

1.65e-0451212EFO_0801623
Diseasegamma-aminobutyric acid receptor-associated protein-like 1 measurement

NLRP12 ATG7

1.65e-0451212EFO_0801613
Diseasegalectin-2 measurement

CFH NLRP12

2.47e-0461212EFO_0020397
DiseaseEna/VASP-like protein measurement

CFH NLRP12

2.47e-0461212EFO_0801564
Diseaseendothelial differentiation-related factor 1 measurement

CFH NLRP12

2.47e-0461212EFO_0801571
Diseasecytochrome c oxidase subunit 6C measurement

CFH NLRP12

2.47e-0461212EFO_0801515
Diseasecyclin-dependent kinase 8:cyclin-c complex measurement

CFH NLRP12

2.47e-0461212EFO_0020297
DiseaseCOMM domain-containing protein 7 measurement

NLRP12 SPDYC

2.47e-0461212EFO_0020273
Diseaseacyl-CoA-binding domain-containing protein 6 measurement

CFH NLRP12

2.47e-0461212EFO_0801342
Diseasesecreted frizzled-related protein 1 measurement

CFH SFRP1

2.47e-0461212EFO_0020718
Diseasetumor necrosis factor ligand superfamily member 18 measurement

CFH HPX

2.47e-0461212EFO_0020795
Diseaseprotein NDRG4 measurement

CFH NLRP12

2.47e-0461212EFO_0801954
Diseasenischarin measurement

CFH NLRP12

2.47e-0461212EFO_0801841
DiseaseNTF2-related export protein 1 measurement

CFH NLRP12

2.47e-0461212EFO_0801847
Diseasemacrophage colony-stimulating factor 1 receptor measurement

MGAT5 CSF1R

2.47e-0461212EFO_0020547
Diseaseriboflavin kinase measurement

CFH NLRP12

2.47e-0461212EFO_0802016

Protein segments in the cluster

PeptideGeneStartEntry
AMDFTPEEWGKLDPA

ZNF286A

51

Q9HBT8
ELMEKYPCAVPLWVG

CYP4Z2P

71

Q8N1L4
MPIWKFPDEEGACQP

ERBB2

611

P04626
IFEMGWEKPSPIQEE

DDX6

111

P26196
LPGGDWPACAQKIMD

BRAT1

186

Q6PJG6
MRPCWFQLDQIPFKD

NUDT1

101

P36639
GQWDKPLPECIMIDC

CSMD3

2981

Q7Z407
HRPKMEAVPEGDWFC

BAZ2A

1706

Q9UIF9
ASASLQVKGWMCPEP

BAZ2B

1811

Q9UIF8
QVKGWMCPEPASERE

BAZ2B

1816

Q9UIF8
QPEGMLDKFSWSELC

CCDC171

586

Q6TFL3
VPVEVMGFPEFADCW

APOBEC3H

131

Q6NTF7
MPGPRQELLCAFWKS

ADGRE5

486

P48960
ITEPEKGYMRPEACW

ADGRF4

536

Q8IZF3
IKDNPFCEFITVPWM

ASB15

476

Q8WXK1
LWNMSDDKPFLCTAP

ATF2

16

P15336
DWPFGAEMCKLVPFI

EDNRB

166

P24530
DEEVMCLNGNWTEPP

CFH

1086

P08603
VNLECFEEDPGRKWM

APEX2

211

Q9UBZ4
EECPSGIPIDMWNKF

FAM204A

66

Q9H8W3
GKPFSCSPLQLDQWM

ATP2B2

1051

Q01814
PEDWPVYQEGCMEKV

CD82

206

P27701
KRWMEACLGEDLPPT

IQGAP1

51

P46940
MAEKLGCFWPNAEVD

RAMP1

76

O60894
EADDWCVPSREPKDM

PDK1

416

Q15118
GWPEVVEMEGCIPQK

FAM3C

211

Q92520
GCTDPEIKASPQMWA

NTM-AS1

11

Q6ZSK4
WESPLDEVDKMCHLP

PRKCQ

346

Q04759
FDEWMFGKVGCKLIP

NMBR

106

P28336
YEGWPELLEMEGCMP

FAM3D

206

Q96BQ1
VPDCLLESMPKEWNY

KIAA0825

936

Q8IV33
EKQDFCHGQVMWPPL

MGAT5

621

Q09328
MKCWKAALVPPNFGE

FAM90A1

61

Q86YD7
GWMALDEFLVKNDPC

DST

7336

Q03001
CEALAFPSPNITWMK

HMCN2

2571

Q8NDA2
FCVVDEPPGIADMWD

DSG4

526

Q86SJ6
WLCDPDAMEQGETPL

CAND1

411

Q86VP6
SDPKFPDCSGKVEWM

MGAT5B

161

Q3V5L5
WKIPESCRPNMEEGI

PLXND1

1396

Q9Y4D7
KLPDGMDQLPEKWYC

MORC3

421

Q14149
ESPPEEGWEEQMCVK

PFKP

241

Q01813
DWVPLSPGMKCTQEE

FREM1

1331

Q5H8C1
QIDGEPWMQTPCTIK

DGKA

696

P23743
IWQFEDLVPCGVFMK

PRCP

206

P42785
EQGEEPWIMEGEFPC

PMS2P3

66

Q13401
GWMALDEFLVKNDPC

MACF1

3301

O94854
APRCPNDNMKFEWSP

LY6L

76

H3BQJ8
PLKLYCNGDGEWMVP

EPHB3

251

P54753
ETWMEKERQKDEPPC

ANO1

946

Q5XXA6
WDEKMECFKVQPVIG

OSBP

646

P22059
CFEDPEWKQLMGQVL

MYBBP1A

1046

Q9BQG0
EKDYPDTWVCSMNPD

MORC2

516

Q9Y6X9
DMIFLKWEEPQEPNG

PTPRU

501

Q92729
FVCQAEGIPSPKMSW

PRTG

346

Q2VWP7
QDVTVMEPAPAWFEC

OBSCN

2386

Q5VST9
EDILCAEFPDEPKWM

PREP

221

P48147
MLECWNAEPKERPTF

FRK

466

P42685
MTCPDKPGQLINWFI

GASK1B

1

Q6UWH4
QPHMCGWEDSQKPSV

GUCA1ANB

11

X6R8D5
KGVKWMRPHEFCAEP

CAPN12

71

Q6ZSI9
LTCWDPEENKMAPCE

HLA-DMB

51

P28068
RLPVKWMAPESIFDC

CSF1R

816

P07333
SRCGMVFVDPEELKW

DNAH6

1891

Q9C0G6
SPGDWMCPVNKGDDK

HECTD1

481

Q9ULT8
MCFDPDTDKWIQKAP

KLHL13

506

Q9P2N7
EMAFSPDCPKAVGWE

ATG7

291

O95352
QGVAWTKMPVCEEIF

CR2

261

P20023
MDVTLLDEHGKPFWC

FBXO15

426

Q8NCQ5
TWECLQPMKGDPVIY

FNDC3A

1066

Q9Y2H6
VPNENYCKFEDWLMP

DHPS

171

P49366
KMCVAPGEAEPIWVV

CPAMD8

861

Q8IZJ3
MDPKLCPADPDWIAF

DPP8

216

Q6V1X1
FDKMEGNPICVQIPW

CRY1

306

Q16526
VIPKFCFPDSKDWMP

DENND2C

536

Q68D51
KMVDCGPPVQWADVA

FIGNL2

381

A6NMB9
PWQNEMIESGCFKDI

GRK4

511

P32298
CLDPDMEKAPEGKWS

CHD4

396

Q14839
CEWLPQAMHPDIEKA

DHX37

1136

Q8IY37
KDFWNQCMPDHVIPE

DHX40

411

Q8IX18
PSDEGLWDMFVKDIP

SDK1

1941

Q7Z5N4
PMCDILWSDPLEDFG

PPP3CA

226

Q08209
EPFAKLMEDCWNPDP

MAP3K9

376

P80192
PNLGWMCIDATDPEK

PRDM2

81

Q13029
LYNWSLNCPKDVEMP

OTOGL

1496

Q3ZCN5
IKFQEDGSWCPMRPK

PIAS2

416

O75928
CSPEAVWPKTEPLEM

IRF6

186

O14896
KQDGFPEQCIPVWMF

NTMT2

261

Q5VVY1
EVMPAQWEFQIGPCE

GLUL

196

P15104
LPWPHEKVDGALCME

HPX

396

P02790
TFPGWKDPAMVCIFV

SLC35D3

216

Q5M8T2
EKPMEDEDRYTTCWP

SERAC1

421

Q96JX3
PLWNDGCIMGFISKE

STAT1

571

P42224
WKPDGVQTQMAPQDC

PPP1R3C

261

Q9UQK1
WKGMEEPGEKTELFC

SYNE2

1966

Q8WXH0
MEWNPGFPLSIDAKC

ALOX5

146

P09917
EPFAKLMKECWQQDP

MAP3K21

371

Q5TCX8
PWAEPEEMSEEKCGF

SLC17A7

496

Q9P2U7
EKCGSLVPVWDMPEH

POLH

636

Q9Y253
PVFEQLEEKLCEWMG

SCFD2

131

Q8WU76
MEELEESRQKCPPCW

SCN3A

716

Q9NY46
QIPDGMCIDAEGKLW

RGN

201

Q15493
WPEMLKCDKFPEGDV

SFRP1

151

Q8N474
LPQCKEDAEEWTYPM

STYX

11

Q8WUJ0
EFVDSLHGQPKMPEW

OMA1

421

Q96E52
CWIDPLSMGPQKALE

RPTOR

86

Q8N122
AATTWEKMGQCALPP

SLX4

916

Q8IY92
PMTKADLEQCWDIPN

CLUL1

236

Q15846
EIQFMEDGSWCPMKP

PIAS3

396

Q9Y6X2
PVPADKMWGLAEFHC

SHFL

141

Q9NUL5
MIANDVTGPWCPDLE

ZNF565

106

Q8N9K5
IMFDGPEAWGVCEPQ

ZER1

641

Q7Z7L7
DLITCLEQGKEPWNM

ZNF724

51

A8MTY0
MEEDLEGPKCEIFPW

SPDYC

121

Q5MJ68
DLITCLEQGKEPWNM

ZNF723

51

P0DPD5
ERCLYMWPSVPDEKG

PIK3CD

436

O00329
EDMIGYRPPSLIKWC

SLC6A11

501

P48066
EALDVCEMWGEMPPL

nan

156

A6NLC8
LSPEGMVWFLCGPEN

PLCB2

286

Q00722
GIPPDEMDEFGLCKW

CAD

61

P27708
DLITCLEQGKEPWNM

ZNF708

51

P17019
EDPMPESKVGDTCVW

ZFP62

31

Q8NB50
TGENCFMPDWFEAKL

TARBP1

621

Q13395
HKLECSPMVVFGENW

SMYD2

86

Q9NRG4
SHDNMEEKVPWVCPR

PPP1R10

451

Q96QC0
FSVPDVPKSMAWCEN

VPS39

161

Q96JC1
ECSMQDLIFSCWPEP

NLRP12

261

P59046
VACEAKGEPMPKVTW

MXRA5

2366

Q9NR99