Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontubulin binding

CCDC88A KIF3B BRCA2 PAFAH1B1 KIF16B RP1 GNAS NIN

1.83e-05428548GO:0015631
GeneOntologyMolecularFunctioncytoskeletal protein binding

EEF2 CCDC88A KIF3B BRCA2 MYH7B PAFAH1B1 KIF16B LSP1 RP1 GNAS NIN

1.44e-0410995411GO:0008092
GeneOntologyMolecularFunctionmicrotubule binding

CCDC88A KIF3B PAFAH1B1 KIF16B RP1 NIN

1.78e-04308546GO:0008017
GeneOntologyMolecularFunctionpyridoxal phosphate binding

SPTLC2 ACCSL KYNU

4.68e-0456543GO:0030170
GeneOntologyMolecularFunctionvitamin B6 binding

SPTLC2 ACCSL KYNU

4.93e-0457543GO:0070279
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF3B KIF16B

9.51e-0417542GO:0008574
GeneOntologyMolecularFunctiondynein heavy chain binding

DNAI4 DYNC1LI2

9.51e-0417542GO:0045504
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

IQCA1L EEF2 KIF3B SAR1B RSF1 KIF16B GNAS DHX30

1.06e-03775548GO:0017111
GeneOntologyMolecularFunctionATP-dependent activity

IQCA1L WAPL KIF3B MYH7B RSF1 KIF16B DHX30

1.27e-03614547GO:0140657
GeneOntologyMolecularFunctionpyrophosphatase activity

IQCA1L EEF2 KIF3B SAR1B RSF1 KIF16B GNAS DHX30

1.76e-03839548GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

IQCA1L EEF2 KIF3B SAR1B RSF1 KIF16B GNAS DHX30

1.77e-03840548GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

IQCA1L EEF2 KIF3B SAR1B RSF1 KIF16B GNAS DHX30

1.77e-03840548GO:0016818
GeneOntologyMolecularFunctiondynein complex binding

CNTRL PAFAH1B1

2.59e-0328542GO:0070840
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CDKN1B IQCA1L CCDC88A KIF3B BRCA2 CNTRL PAFAH1B1 DNAI4 RP1 DYNC1LI2 NIN

2.56e-067205511GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

CDKN1B IQCA1L CCDC88A KIF3B BRCA2 CNTRL PAFAH1B1 KIF16B DNAI4 RP1 DYNC1LI2 NIN

1.76e-0510585512GO:0007017
GeneOntologyBiologicalProcesscilium assembly

NEK1 CCDC88A KIF3B CEP162 CNTRL DNAI4 C11orf97 RP1

2.17e-05444558GO:0060271
GeneOntologyBiologicalProcesscilium organization

NEK1 CCDC88A KIF3B CEP162 CNTRL DNAI4 C11orf97 RP1

3.57e-05476558GO:0044782
GeneOntologyBiologicalProcesscentrosome localization

PAFAH1B1 DYNC1LI2 NIN

1.11e-0435553GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

PAFAH1B1 DYNC1LI2 NIN

1.20e-0436553GO:0061842
GeneOntologyBiologicalProcesscorpus callosum morphogenesis

PAFAH1B1 NIN

1.93e-048552GO:0021540
GeneOntologyCellularComponentspindle

WAPL ZZZ3 KIF3B CEP162 CNTRL PAFAH1B1 KIF16B CDC25B TAF1D NIN

3.62e-074715510GO:0005819
GeneOntologyCellularComponentmicrotubule organizing center

NEK1 CCDC88A KIF3B BRCA2 CEP162 CNTRL PAFAH1B1 C11orf97 CDC25B DYNC1LI2 TAF1D NIN

3.71e-069195512GO:0005815
GeneOntologyCellularComponentmicrotubule associated complex

KIF3B PAFAH1B1 KIF16B DNAI4 RP1 DYNC1LI2

4.03e-06161556GO:0005875
GeneOntologyCellularComponentcentrosome

NEK1 CCDC88A KIF3B BRCA2 CEP162 CNTRL PAFAH1B1 CDC25B DYNC1LI2 TAF1D NIN

4.29e-067705511GO:0005813
GeneOntologyCellularComponentCOPI-coated Golgi to ER transport vesicle

CCDC88A GNAS

6.80e-062552GO:0030142
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

KIF3B CEP162 CNTRL PAFAH1B1 DNAI4 RP1

1.80e-04317556GO:0032838
GeneOntologyCellularComponentmitotic spindle

WAPL ZZZ3 CNTRL TAF1D NIN

1.84e-04201555GO:0072686
GeneOntologyCellularComponentkinesin complex

KIF3B PAFAH1B1 KIF16B

2.91e-0449553GO:0005871
GeneOntologyCellularComponentcentriolar subdistal appendage

CNTRL NIN

3.02e-0410552GO:0120103
GeneOntologyCellularComponentcytoplasmic region

KIF3B CEP162 CNTRL PAFAH1B1 DNAI4 RP1

3.56e-04360556GO:0099568
GeneOntologyCellularComponentcentriolar satellite

NEK1 CEP162 CNTRL TAF1D

3.59e-04128554GO:0034451
GeneOntologyCellularComponentmicrotubule

KIF3B CEP162 PAFAH1B1 KIF16B RP1 DYNC1LI2 NIN

4.74e-04533557GO:0005874
GeneOntologyCellularComponentcilium

CCDC88A KIF3B CEP162 CNTRL PAFAH1B1 DNAI4 C11orf97 RP1 NIN

5.14e-04898559GO:0005929
GeneOntologyCellularComponentaxoneme

CEP162 CNTRL DNAI4 RP1

2.15e-03207554GO:0005930
GeneOntologyCellularComponentciliary plasm

CEP162 CNTRL DNAI4 RP1

2.18e-03208554GO:0097014
GeneOntologyCellularComponentpericentriolar material

NEK1 NIN

2.46e-0328552GO:0000242
GeneOntologyCellularComponentCOPI-coated vesicle

CCDC88A GNAS

3.41e-0333552GO:0030137
GeneOntologyCellularComponentchromosomal region

WAPL NUP107 BRCA2 PAFAH1B1 DYNC1LI2

4.93e-03421555GO:0098687
GeneOntologyCellularComponentaggresome

EEF2 TRIM50

4.97e-0340552GO:0016235
GeneOntologyCellularComponentcytoplasmic microtubule

CEP162 PAFAH1B1 NIN

5.19e-03133553GO:0005881
Domain-

SPTLC2 ACCSL KYNU

1.25e-04355233.90.1150.10
DomainPyrdxlP-dep_Trfase_major_sub2

SPTLC2 ACCSL KYNU

1.36e-0436523IPR015422
Domain-

SPTLC2 ACCSL KYNU

1.73e-04395233.40.640.10
DomainPyrdxlP-dep_Trfase

SPTLC2 ACCSL KYNU

2.01e-0441523IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

SPTLC2 ACCSL KYNU

2.01e-0441523IPR015421
DomainAminotransferase_I/II

SPTLC2 ACCSL

1.01e-0317522IPR004839
DomainAminotran_1_2

SPTLC2 ACCSL

1.01e-0317522PF00155
DomainC2H2_Znf_fam

ZNF202 ZNF518A

2.02e-0324522IPR027775
DomainP-loop_NTPase

EEF2 KIF3B MYH7B SAR1B KIF16B GNAS DYNC1LI2 DHX30

2.23e-03848528IPR027417
DomainKinesin_motor_CS

KIF3B KIF16B

5.82e-0341522IPR019821
DomainKinesin-like_fam

KIF3B KIF16B

6.38e-0343522IPR027640
DomainKINESIN_MOTOR_1

KIF3B KIF16B

6.67e-0344522PS00411
Domain-

KIF3B KIF16B

6.67e-03445223.40.850.10
DomainKinesin_motor_dom

KIF3B KIF16B

6.67e-0344522IPR001752
DomainKinesin

KIF3B KIF16B

6.67e-0344522PF00225
DomainKINESIN_MOTOR_2

KIF3B KIF16B

6.67e-0344522PS50067
DomainKISc

KIF3B KIF16B

6.67e-0344522SM00129
PathwayREACTOME_CELL_CYCLE

CDKN1B WAPL NUP107 BRCA2 CNTRL PAFAH1B1 RSF1 CDC25B MDM4 DYNC1LI2

3.43e-056944310M543
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

NEK1 CEP162 CNTRL PAFAH1B1 DYNC1LI2 NIN

1.50e-0714657621399614
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EEF2 CCDC88A BBX NUP107 CEP162 CNTRL SAR1B HUWE1 SLC39A10 DYNC1LI2

4.89e-07777571035844135
Pubmed

CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation.

CNTRL NIN

2.64e-06257211956314
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CCDC88A ZZZ3 NUP107 BRCA2 GNAS HUWE1 MDM4 NIN

5.08e-0658857838580884
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

EEF2 CNTRL HUWE1 SOS2

5.18e-066957432238831
Pubmed

CacyBP/SIP inhibits the migration and invasion behaviors of glioblastoma cells through activating Siah1 mediated ubiquitination and degradation of cytoplasmic p27.

CDKN1B SIAH1

7.91e-06357229024247
Pubmed

Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress.

CDKN1B SIAH1

7.91e-06357221734459
Pubmed

No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.

CDKN1B BRCA2

7.91e-06357218543099
Pubmed

Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.

NEK1 WAPL

7.91e-06357227760328
Pubmed

MDM4 is a rational target for treating breast cancers with mutant p53.

CDKN1B MDM4

7.91e-06357228097652
Pubmed

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

BRCA2 LSP1

1.58e-05457219656774
Pubmed

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes.

KIF3B NIN

1.58e-05457225564561
Pubmed

GIV/Girdin activates Gαi and inhibits Gαs via the same motif.

CCDC88A GNAS

1.58e-05457227621449
Pubmed

Defining the membrane proteome of NK cells.

EEF2 KIF3B NUP107 CNTRL DOCK10 GOLIM4 LSP1 GNAS HUWE1 DYNC1LI2

1.81e-051168571019946888
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

KIF3B HUWE1 ZNF518A ZNF646

2.64e-051045749205841
Pubmed

p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.

CDKN1B BRCA2

3.94e-05657216951165
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

ARID4A PAFAH1B1 HUWE1 DHX30 MSI2

6.02e-0525357529911972
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NEK1 CCDC88A ZZZ3 NUP107 BRCA2 HUWE1

6.29e-0541857634709266
Pubmed

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.

CNTRL NIN

7.34e-05857223213374
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

PAFAH1B1 DOCK10 LSP1 HUWE1

9.14e-0514357430397336
Pubmed

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation.

CNTRL NIN

1.18e-041057225220058
Pubmed

Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.

CDKN1B BRCA2

1.18e-041057220484223
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

EEF2 NUP107 PAFAH1B1 RSF1 GOLIM4 GNAS SLC39A10 ZNF518A ZNF646

1.39e-04120357929180619
Pubmed

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

NUP107 HUWE1 DHX30

1.86e-046757329357390
Pubmed

The DNA sequence and comparative analysis of human chromosome 20.

KIF3B MYH7B KIF16B SIRPB1 GNAS CDC25B

2.00e-0451757611780052
Pubmed

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.

EEF2 HUWE1

2.03e-041357229285303
Pubmed

NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction.

EEF2 BRCA2

2.03e-041357228416489
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

CEP162 NIN

2.03e-041357217920017
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WAPL CCDC88A CEP162 KIF16B ZNF646 NIN

2.26e-0452957614621295
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

NEK1 CCDC88A BBX KIF3B NUP107 PAFAH1B1 CDC25B DYNC1LI2 DHX30

2.79e-04132157927173435
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC88A NUP107 CEP162 GOLIM4 HUWE1 SLC39A10 CDC25B NIN

2.97e-04104957827880917
Pubmed

Proteomic analysis identifies novel binding partners of BAP1.

EEF2 GNAS HUWE1

3.14e-048057334591877
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EEF2 WAPL NUP107 SPTLC2 PAFAH1B1 RSF1 DOCK10 HUWE1 DHX30

3.32e-04135357929467282
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

EEF2 CCDC88A GOLIM4 GNAS

3.37e-0420157425192599
Pubmed

Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B.

EEF2 BRCA2

3.97e-041857216712842
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

WAPL ZZZ3 NUP107 RSF1 SIRPB1 ZNF518A ZNF646 NIN

4.49e-04111657831753913
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NEK1 CCDC88A CEP162 GNAS CDC25B MDM4 PTER

5.01e-0486157736931259
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

EEF2 DNAI4 SIRPB1

5.19e-049557324029230
Pubmed

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

BRCA2 MDM4

5.43e-042157223535733
Pubmed

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

CDKN1B HUWE1

5.43e-042157219686682
Pubmed

Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes.

CDKN1B CDC25B

5.43e-042157224821722
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CDKN1B WAPL NUP107 PAFAH1B1 GNAS CDC25B DYNC1LI2 DHX30

5.63e-04115557820360068
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIF16B HUWE1 NIN

6.21e-0410157310997877
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

CNTRL CDC25B NIN

6.39e-0410257320508983
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

BBX ARID4A CEP162 RSF1 HUWE1 NIN

6.46e-0464557625281560
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

WAPL CCDC88A TLL1 DOCK10 CDC25B KYNU

6.73e-0465057638777146
Pubmed

Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.

NIN SOS2

7.12e-042457224347629
Pubmed

CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.

DOCK10 LSP1 C7 GNAS DHX30

7.73e-0444057535156780
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF3B KIF16B

7.73e-04255729275178
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

CCDC88A NUP107 KIF16B NIN

7.75e-0425157429778605
Pubmed

O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma.

EEF2 PAFAH1B1 GNAS MSI2

8.10e-0425457436604567
Pubmed

Epidermal development requires ninein for spindle orientation and cortical microtubule organization.

PAFAH1B1 NIN

8.36e-042657230923192
Pubmed

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.

WAPL SPTLC2 RP1 GNAS DYNC1LI2

8.80e-0445357527113764
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

NEK1 KIF3B RSF1 TRIM50 MSI2 ZNF646

9.10e-0468957636543142
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EEF2 WAPL ZZZ3 BBX BRCA2 ARID4A RSF1

9.16e-0495457736373674
Pubmed

CRL4AMBRA1 is a master regulator of D-type cyclins.

CDKN1B PAFAH1B1

1.11e-033057233854235
Pubmed

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer.

EEF2 GNAS

1.11e-033057234285210
Pubmed

A catalogue of putative HIV-1 protease host cell substrates.

EEF2 ZNF202 HUWE1

1.12e-0312457322944692
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

CDKN1B BBX BRCA2

1.15e-0312557321654808
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

CDKN1B WAPL NUP107 HUWE1

1.29e-0328857423383273
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

EEF2 NUP107 RSF1 HUWE1 DYNC1LI2

1.40e-0350357516964243
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

CDKN1B NUP107

1.43e-033457218539113
Pubmed

Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.

CDKN1B PAFAH1B1

1.43e-033457223533177
Pubmed

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.

WBP1L MSI2

1.52e-033557228106071
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

EEF2 CCDC88A SLC39A10 ALPK2 DYNC1LI2

1.53e-0351357525798074
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

SPTLC2 GNAS NIN

1.56e-0313957325476789
Pubmed

Evolutionarily conserved regulators of tau identify targets for new therapies.

EEF2 SPTLC2 PAFAH1B1 GOLIM4 SLC39A10

1.56e-0351657536610398
Pubmed

Gene expression in pharyngeal arch 1 during human embryonic development.

EEF2 GNAS

1.60e-033657215703188
InteractionCDK1 interactions

CDKN1B BRCA2 ARID4A SAR1B PAFAH1B1 RSF1 HUWE1 CDC25B MDM4 MSI2

3.21e-065905410int:CDK1
InteractionCCNB1 interactions

CDKN1B BRCA2 ARID4A CEP162 CNTRL CDC25B NIN

3.82e-06244547int:CCNB1
Cytoband11q21

C11orf97 TAF1D

1.39e-034457211q21
CytobandEnsembl 112 genes in cytogenetic band chr1p31

ASB17 ZZZ3 DNAI4

2.76e-03224573chr1p31
CytobandEnsembl 112 genes in cytogenetic band chr11q21

C11orf97 TAF1D

2.82e-0363572chr11q21
Cytoband1p31.1

ASB17 ZZZ3

3.56e-03715721p31.1
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

CDKN1B WAPL CCDC88A BBX ARID4A CNTRL PAFAH1B1 RSF1 DOCK10 LSP1 GNAS HUWE1 MDM4 NIN

2.69e-0614925714M40023
CoexpressionHALLMARK_MITOTIC_SPINDLE

CCDC88A KIF3B BRCA2 CNTRL PAFAH1B1 NIN

4.67e-06199576M5893
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

NEK1 CCDC88A ZZZ3 BBX RSF1 KIF16B DOCK10 GOLIM4 NIN

1.12e-05656579M18979
CoexpressionGOLDRATH_HOMEOSTATIC_PROLIFERATION

PAFAH1B1 GOLIM4 SIAH1 TAF1D SOS2

1.89e-05150575M3592
CoexpressionGOLDRATH_HOMEOSTATIC_PROLIFERATION

PAFAH1B1 GOLIM4 SIAH1 TAF1D SOS2

2.36e-05157575MM613
CoexpressionGABRIELY_MIR21_TARGETS

NEK1 ARID4A CNTRL RSF1 DOCK10 DYNC1LI2

3.86e-05289576M2196
CoexpressionGSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN

MYH7B CNTRL DOCK10 MDM4 ZNF646

7.12e-05198575M7708
CoexpressionGSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP

CCDC88A ARID4A CNTRL ZNF518A ZNF646

7.29e-05199575M6443
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE

BBX ZNF202 GNAS MDM4 DYNC1LI2 DHX30 MSI2

7.33e-05474577M40991
CoexpressionHALLMARK_G2M_CHECKPOINT

CDKN1B BRCA2 ARID4A PAFAH1B1 CDC25B

7.46e-05200575M5901
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CDKN1B NEK1 WAPL ZZZ3 BBX BRCA2 ARID4A PAFAH1B1 SOS2

8.93e-05856579M4500
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

CDKN1B CCDC88A BRCA2 ARID4A CEP162 TLL1 CNTRL RSF1 CDC25B DHX30 TAF1D MSI2 SOS2

2.91e-0513705413facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

WAPL CCDC88A BRCA2 ARID4A TLL1 CNTRL RSF1 SLC39A10 ZNF518A DHX30 TAF1D MSI2

5.71e-0512525412facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NEK1 CCDC88A BRCA2 ARID4A CEP162 ZNF518A

1.35e-04311546Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

CCDC88A BRCA2 ARID4A CEP162 GOLIM4 DNAI4 HUWE1 DHX30 NIN

1.40e-04780549Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

WAPL BBX BRCA2 ARID4A RSF1 SLC39A10 ZNF518A

1.77e-04469547Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_200

TLL1 HUWE1 PTER

2.18e-0446543DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

NEK1 CCDC88A BRCA2 ARID4A CEP162 GOLIM4 DNAI4 HUWE1 ZNF518A

2.25e-04831549Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

CCDC88A ARID4A PAFAH1B1 RSF1 HUWE1 ZNF518A SOS2

2.37e-04492547gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CCDC88A ARID4A RSF1 CDC25B DHX30 TAF1D

1.97e-071975760fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A CNTRL RSF1 DOCK10 NIN

3.92e-061855757adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-mDC|LPS_only / Treatment groups by lineage, cell group, cell type

CCDC88A DOCK10 LSP1 KYNU ALPK2

5.46e-0619857553c22e81e530d6fc272d4a45c8d1bf125feb254d
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC88A DOCK10 LSP1 KYNU ZNF646

5.59e-0619957582759af613ebfffe037afda55159bf6af812c3ac
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

CCDC88A ARID4A RSF1 GOLIM4 ANKRD18B

5.59e-06199575a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R3A CCDC88A DOCK10 LSP1

3.88e-0514857412fa2c4922f03803006c606b1b16e79441e3bb13
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRCA2 CEP162 ZNF202 ANKRD18B

3.98e-0514957454c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BRCA2 CEP162 ZNF202 ANKRD18B

3.98e-0514957414d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A ARID4A MYH7B LSP1

5.13e-05159574807ee55fe0d3645fbfb98f641dd0a0555b847cf5
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DNAI4 C11orf97 RP1 ANKRD18B

5.78e-051645740e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC88A DOCK10 LSP1 KYNU

6.20e-05167574fd84a99ea142d1684cdcf4a88ef1d541760bc78a
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NEK1 CEP162 CDC25B MDM4

6.65e-05170574070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A BRCA2 DOCK10 LSP1

7.60e-051765745f8c1f917fba49f3b1c0d88b946eca242b668fde
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1B CCDC88A PAFAH1B1 GOLIM4

7.60e-05176574749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellwk_15-18-Hematologic-Myeloid-aDC_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOCK10 LSP1 KYNU ALPK2

7.77e-05177574ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 LSP1 KYNU ALPK2

8.66e-051825740f06309318c064f0ebdb12a46226b90032290137
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A CNTRL DOCK10 NIN

8.66e-05182574f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

CCDC88A DOCK10 LSP1 KYNU

8.84e-05183574703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

CCDC88A DOCK10 LSP1 KYNU

8.84e-05183574b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A CNTRL RSF1 DOCK10

9.03e-051845741154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell3'|World / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EEF2 GOLIM4 MDM4 ZNF518A

9.41e-05186574e265aac37f33947ff6c83f23f8a2c63bbccd60af
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

WAPL ARID4A KIF16B GOLIM4

9.41e-0518657403db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A BRCA2 CNTRL DOCK10

9.61e-0518757473931a5ea73799095daff100b5f18853c57c74dc
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

DNAI4 C11orf97 RP1 ANKRD18B

9.61e-051875746fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL CNTRL GOLIM4 ZNF518A

1.04e-0419157460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellMonocytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SPTLC2 CNTRL LSP1 KYNU

1.04e-04191574ca0a5dc82cdef02e88fed937ca5784761896af33
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

CCDC88A KIF16B DOCK10 KYNU

1.04e-04191574dab953682b8c9ed680a799161f837f792a7e4f33
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL CNTRL GOLIM4 ZNF518A

1.04e-0419157409db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WAPL CNTRL GOLIM4 ZNF518A

1.04e-04191574973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellnormal_Lung-Epithelial_cells-Undetermined|Epithelial_cells / Location, Cell class and cell subclass

CCDC88A LSP1 SIRPB1 KYNU

1.13e-0419557431710a593d503e46acad1db38adacace4d863388
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid|BALF-PFMC / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDKN1B EEF2 LSP1 GNAS

1.15e-041965746361c37b0292ba9e5bf485a4809d2b0cd894c26e
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

CCDC88A SPTLC2 DOCK10 KYNU

1.15e-0419657404d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellMegakaryocytic-erythropoietic-MEP|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

EEF2 LSP1 TAF1D MSI2

1.15e-04196574f90e7fe3a7b2fff30d01a25cc500876861c2e4f1
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC88A DOCK10 SIRPB1 SLC39A10

1.15e-041965745fe6534af65d43eeacd4b031310242b4f706008b
ToppCellMegakaryocytic-erythropoietic-MEP-MEP|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

EEF2 LSP1 TAF1D MSI2

1.15e-041965744e97010185fa9392da8f69e7b2a7395bf063f8ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A DOCK10 LSP1 KYNU

1.17e-0419757457dafb3047745a44b2345b8036e159c3641d496e
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC88A DOCK10 LSP1 KYNU

1.17e-04197574363ae03310f63a586ba3cea2a59f35d5a335a54e
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells|LPS_only / Treatment groups by lineage, cell group, cell type

CCDC88A DOCK10 LSP1 KYNU

1.17e-0419757459ddd8ff7dddf3747b988374e1a4d80959db803e
ToppCell10x3'2.3-week_17-19-Lymphocytic_B|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BBX GNAS MDM4 MSI2

1.20e-041985745f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BBX GNAS MDM4 MSI2

1.20e-0419857477ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CCDC88A CEP162 CNTRL RSF1

1.20e-0419857476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A DOCK10 LSP1 KYNU

1.20e-04198574623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CEP162 CNTRL RSF1 GNAS

1.22e-0419957461b1ed2db71b96157b92b7535d1955a4033098da
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC88A DOCK10 LSP1 ALPK2

1.22e-041995747b3d4c62b11268c7c1599600d8a7b331287cf21a
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

CCDC88A ARID4A RSF1 TAF1D

1.22e-0419957419674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

CCDC88A BBX RSF1 GOLIM4

1.22e-0419957418a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellParenchyma_Control_(B.)-Immune-TX-TRAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CCDC88A KIF16B DOCK10 KYNU

1.24e-042005747c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAI4 C11orf97 RP1 ANKRD18B

1.24e-042005746a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellBiopsy_IPF-Immune|Biopsy_IPF / Sample group, Lineage and Cell type

CCDC88A DOCK10 LSP1 KYNU

1.24e-0420057431067dcf63030144679fca20fa41d665cb0035b7
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC88A DOCK10 LSP1 KYNU

1.24e-04200574f19b729b03b5f225b9ed676f0ac31071a4354da3
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC88A SPTLC2 SIRPB1 KYNU

1.24e-042005744943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

PPP1R3A WAPL ALPK2

1.89e-0487573fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

ZNF37A DYNC1LI2 ZNF518A

6.87e-04135573ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

C11orf97 RP1 C7

7.02e-0413657367d736096d6b6ddb4722809557f5e987063b8d23
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

C11orf97 RP1 C7

7.02e-0413657347663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

C11orf97 RP1 C7

7.02e-041365736d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

C11orf97 RP1 C7

7.02e-04136573fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

C11orf97 RP1 C7

7.02e-041365733f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NUP107 BRCA2 ZNF202

8.45e-04145573b17699f7f98d2361a4d26c26f52db05e7ff69dff
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC88A LSP1 KYNU

8.96e-04148573cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DNAI4 C11orf97 RP1

9.49e-041515739d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7B C11orf97 C7

9.68e-04152573d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7B C11orf97 C7

9.68e-04152573d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A MYH7B LSP1

1.10e-031595737bb76324d2026d4bd348126cb169c8411f0d7145
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A DOCK10 LSP1

1.12e-031605735c28121916a12dbc22ef2421040bdc9148a40b78
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A DOCK10 LSP1

1.12e-03160573b7093678987575f2f99d648821d31b4a37075aca
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Pdyn_(Neuron.Gad1Gad2.Sst-Pdyn)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IQCA1L ALPK2

1.13e-0339572a24eb4c26344c5c97bbf39a1adc56ee34013dc4f
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Pdyn_(Neuron.Gad1Gad2.Sst-Pdyn)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IQCA1L ALPK2

1.13e-03395728b5d15f979a92799a9e77f1b501d3c4fa4e8695a
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

DOCK10 MDM4 MSI2

1.16e-03162573b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

DNAI4 C11orf97 RP1

1.18e-0316357343194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BBX RP1 ZNF415

1.18e-03163573cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A DOCK10 LSP1

1.20e-0316457343045879505774ac0d9b7f760557955564f06d00
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DNAI4 C11orf97 RP1

1.20e-03164573fd30c55d0d75ef8b9396435d836187168095152b
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A DOCK10 KYNU

1.23e-031655732477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TLL1 C11orf97 RP1

1.23e-0316557382530f96aaefe28a13bad0474bbad043f127a86c
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TLL1 C11orf97 RP1

1.23e-031655730c714e852f912b5749de4cb0895406673979b2e6
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 LSP1 ALPK2

1.23e-031655738a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LSP1 KYNU ALPK2

1.25e-0316657375d719617c61409860f298ce91cbe3a0aafa0553
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

C7 PTER ZNF415

1.25e-0316657365dafed953b01a9830b54309af75c7a561e88336
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EEF2 C7 GNAS

1.25e-03166573c5a77a28f9819ce28828365ff31884fa2b57e032
ToppCelldroplet-Tongue-TONGUE-1m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 LSP1 KYNU

1.27e-03167573e85d97f8b0127663a3295db2b22b8488c0148455
ToppCelldroplet-Tongue-TONGUE-1m-Myeloid|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 LSP1 KYNU

1.27e-03167573ac21c7112b592e30473e693a2bbee81ff0bb0160
ToppCelldroplet-Tongue-TONGUE-1m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 LSP1 KYNU

1.27e-03167573a54e200789db14f41c9fc8d21cd7fa7cedde77ad
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TLL1 PTER ANKRD18B

1.29e-03168573bfa1491e8d433933003778b274710d3a16d973cb
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A SIRPB1 KYNU

1.31e-03169573203971cceeba150d0e8891c92662545e84c77837
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP1R3A MYH7B ALPK2

1.34e-031705733f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK10 LSP1 KYNU

1.34e-031705736686d1797988216c0d9417f21a2537369abce410
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DNAI4 C11orf97 RP1

1.34e-031705738b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A DOCK10 LSP1

1.34e-031705739e94fa0d05abed3438b28296a293767096d517d6
ToppCellPND14-Immune-Immune_Myeloid-DC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC88A DOCK10 LSP1

1.36e-031715738772d6349db24de47f089df2032a80345db7177f
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EEF2 C7 GNAS

1.36e-0317157359d79c3e36a4930af42ebc96f05570641b9fb864
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A DOCK10 ALPK2

1.38e-031725733f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A RP1 ALPK2

1.38e-03172573bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A DOCK10 LSP1

1.38e-03172573cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A RP1 ALPK2

1.38e-03172573ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A LSP1 RP1

1.38e-031725736aab59add5b180cee0ca31179c620e89d352d5c1
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-mDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK10 LSP1 KYNU

1.38e-03172573cc0e2a45fa74ee19e41612c3615729462474003a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A DOCK10 KYNU

1.38e-03172573f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A LSP1 RP1

1.38e-03172573a125ac2db9c8ece95970a93aa6f7918d1dcef886
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A DOCK10 LSP1

1.40e-0317357373f858f2c45d19b9ec8d99ac02c91551790f670c
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A

SPTLC2 CEP162 SIAH1 ZNF415 KYNU SOS2

7.61e-061925663804_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

NEK1 CCDC88A BRCA2 CEP162 DOCK10 SOS2

8.31e-061955663721_DN
DrugVancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; PC3; HT_HG-U133A

CCDC88A CEP162 DOCK10 MDM4 ZNF415 KYNU

9.60e-062005664598_DN
DrugAC1L4C4O

WAPL CCDC88A

3.55e-054562CID000154366
DrugGM193663

PPP1R3A EEF2

5.91e-055562CID000477019
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

WAPL BRCA2 KIF16B SIAH1 SOS2

8.93e-051845652321_DN
DrugResveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A

CCDC88A CEP162 GNAS ZNF415 SOS2

1.01e-041895655084_DN
DrugSelegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; HL60; HT_HG-U133A

NEK1 CCDC88A MDM4 KYNU SOS2

1.04e-041905652465_DN
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; PC3; HT_HG-U133A

CCDC88A BBX SPTLC2 GOLIM4 SOS2

1.04e-041905654307_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

CCDC88A BBX BRCA2 PTER SOS2

1.06e-041915654279_DN
DrugPiribedil hydrochloride [78213-63-5]; Down 200; 12uM; MCF7; HT_HG-U133A

SPTLC2 CEP162 GNAS MDM4 SOS2

1.06e-041915655434_DN
DrugGlycocholic acid [475-31-0]; Down 200; 8.6uM; PC3; HT_HG-U133A

BRCA2 SPTLC2 CEP162 CNTRL SOS2

1.12e-041935656716_DN
DrugHexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; HL60; HG-U133A

WAPL CCDC88A DOCK10 SIAH1 SOS2

1.12e-041935651982_DN
DrugCP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A

SPTLC2 DOCK10 DNAI4 MDM4 KYNU

1.15e-041945653826_DN
Drug(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A

SPTLC2 CEP162 CNTRL SIAH1 DHX30

1.17e-041955653523_DN
DrugFursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; HL60; HT_HG-U133A

ARID4A DOCK10 SIAH1 MDM4 SOS2

1.17e-041955652929_DN
DrugPiperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A

CCDC88A DNAI4 GNAS MDM4 SOS2

1.20e-041965653263_UP
DrugPentoxifylline [6493-05-6]; Down 200; 14.4uM; HL60; HG-U133A

NEK1 CCDC88A KIF3B RSF1 LSP1

1.20e-041965651444_DN
DrugHomosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A

BRCA2 ARID4A SPTLC2 DOCK10 SOS2

1.23e-041975653797_DN
DrugAzathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A

NEK1 CEP162 DOCK10 ZNF202 SOS2

1.23e-041975651528_UP
DrugProxyphylline [603-00-9]; Down 200; 16.8uM; PC3; HT_HG-U133A

NEK1 SPTLC2 CNTRL ZNF415 SOS2

1.23e-041975657290_DN
DrugQuinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A

NEK1 CEP162 CNTRL ZNF202 SIAH1

1.26e-041985653540_DN
DrugPrazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; PC3; HT_HG-U133A

BRCA2 CEP162 DNAI4 KYNU SOS2

1.26e-041985656315_UP
DrugQuinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

BRCA2 CEP162 DOCK10 MDM4 SOS2

1.26e-041985653793_DN
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

DOCK10 LSP1 C7 ZNF646 SOS2

1.29e-041995653786_UP
DrugEstriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

NEK1 CCDC88A CEP162 CNTRL SIAH1

1.29e-041995653563_DN
DrugBenzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A

NEK1 CCDC88A CEP162 CNTRL SIAH1

1.32e-042005653577_DN
Diseasemean platelet volume

BBX ARID4A PAFAH1B1 RSF1 KIF16B DOCK10 SIRPB1 GNAS KYNU MSI2 NIN

1.96e-0610205411EFO_0004584
DiseaseMalignant neoplasm of breast

PPP1R3A CDKN1B EEF2 BRCA2 TLL1 KIF16B GOLIM4 LSP1 MDM4 ZNF646

2.18e-0510745410C0006142
Diseaseinfertility (implicated_via_orthology)

CDKN1B BRCA2

6.86e-057542DOID:5223 (implicated_via_orthology)
DiseasePituitary Adenoma

CDKN1B GNAS

1.17e-049542C0032000
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

CDKN1B C7

2.95e-0414542DOID:10976 (biomarker_via_orthology)
Diseaseestrogen-receptor negative breast cancer

BRCA2 LSP1 MDM4

3.03e-0471543EFO_1000650
Diseaselung small cell carcinoma (is_marker_for)

CDKN1B EEF2

3.88e-0416542DOID:5409 (is_marker_for)
Diseaseimmature platelet count

DOCK10 SIRPB1 GNAS

9.78e-04106543EFO_0803544
Diseaseimmature platelet fraction

DOCK10 SIRPB1 GNAS

1.21e-03114543EFO_0009187
DiseaseMiller Dieker syndrome

BRCA2 PAFAH1B1

1.29e-0329542C0265219
Diseaseplatelet crit

CDKN1B BBX KIF16B DOCK10 RP1 SIRPB1 MSI2

1.68e-03952547EFO_0007985

Protein segments in the cluster

PeptideGeneStartEntry
EERRHTEAICEHEAL

ACCSL

56

Q4AC99
LKHHEDIVDEIECIE

CNTRL

1411

Q7Z7A1
TLVCHEVDLDDLDEK

ARID4A

956

P29374
EIRKEELEEDHKCSH

BBX

391

Q8WY36
THEEERANQIDEKEH

ALPK2

131

Q86TB3
HRDCLENGKEDLLEE

ANKRD18B

586

A2A2Z9
LEERTDKASHEECRE

CD300LD-AS1

171

Q96MU5
VDHEELTRDLEKHCR

CDKN1B

36

P46527
HHESEDECALDLDLV

DHX30

641

Q7L2E3
CEHDKESRLLEKHDE

KIF16B

866

Q96L93
EDVVEKVCEIHFHEI

MSI2

161

Q96DH6
KECKAELREHEHVVE

PAFAH1B1

266

P43034
DVREDAKEDHERTHQ

NUP107

831

P57740
AIHEDEDENIEICSK

NEK1

1211

Q96PY6
SEHKCIHSREDEDLI

MDM4

161

O15151
VDRELADIHEDAKTC

ASB17

196

Q8WXJ9
LSVHDEDRDDHTRCN

DYNC1LI2

91

O43237
RAEELENELHHLEKE

CCDC88A

626

Q3V6T2
RHDCDLLREQHEEEA

MYH7B

1386

A7E2Y1
LCHDEIENLLDSDHR

CDC25B

376

P30305
GECLKELEESHDQHA

HUWE1

3861

Q7Z6Z7
EEGCEDRILVAHDIH

PTER

286

Q96BW5
DVNREHDEHNEKELE

PPP1R3A

306

Q16821
EELKKQHSDLEEEHR

GOLIM4

126

O00461
EEHQVEEEHRKALEE

GOLIM4

331

O00461
DIVAKCHEEQLDHSV

DOCK10

931

Q96BY6
NKRDEEQHLESHTDC

BRCA2

466

P51587
ESTQCEDEELEHLRL

C7

541

P10643
HEHEEADLELSLPEC

GNAS

86

O95467
TDDEHENESKHEELA

CEP162

176

Q5TB80
EDEEEAVHEQCQHER

LSP1

26

P33241
ENVILAKIHEDEEDH

DNAI4

376

Q5VTH9
ELHLEICLKDLEEDH

EEF2

551

P13639
HRIETDEEESCDNAH

RSF1

1301

Q96T23
KDLNEDDHHHECLNV

SLC39A10

326

Q9ULF5
HEDLLDVRNETCAKE

RP1

1831

P56715
DKEDTCEHKHAFELV

SOS2

501

Q07890
VLHDNKHDCKEAECE

TLL1

761

O43897
EEAERHKEDLEQHSR

TMEM191B

131

P0C7N4
LKEAHHEATCRHEEE

NIN

686

Q8N4C6
EDATHLEDNECDIKL

TAF1D

216

Q9H5J8
ELKDELVRADLCENH

IQCA1L

86

A6NCM1
HTEKADHEELCEFRP

SIAH1

111

Q8IUQ4
AHRDDVKLTCQVEHD

SIRPB1

321

Q5TFQ8
EEERHIKRDECHIKN

C11orf97

66

A0A1B0GVM6
KCFCDEKHEIIHSEE

ZNF37A

101

P17032
IEKCHHATEREEQKD

SPTLC2

96

O15270
HDLQEEHIKERQELE

KIF3B

556

O15066
DQDHVCKHEEEATDI

ZNF646

551

O15015
CVDHLSRDEDEEKLV

WAPL

831

Q7Z5K2
QEHLSEEKDERLHCE

ZNF518A

366

Q6AHZ1
LEQHEKHDIEEFCFR

ZNF415

121

Q09FC8
DCADHERLLESKEEL

SAR1B

101

Q9Y6B6
ELHHLVDEEKARCLE

TRIM50

181

Q86XT4
CLHETDIHKEDHQLE

ZZZ3

856

Q8IYH5
ECLEQEDLSLEDIHR

ZNF202

326

O95125
AECREELLKDDSSEH

WBP1L

216

Q9NX94
LHLDEEDKLRHFREC

KYNU

31

Q16719