Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type peptidase activity

PREPL DPP10

7.74e-03207132GO:0008236
GeneOntologyMolecularFunctionpeptidase activity

PREPL ADAM5 DPP10

7.82e-03654133GO:0008233
GeneOntologyMolecularFunctionserine hydrolase activity

PREPL DPP10

8.10e-03212132GO:0017171
MousePhenodecreased lumbar vertebrae number

PIK3CB LASP1

1.13e-043372MP:0004647
MousePhenodecreased presacral vertebrae number

PIK3CB LASP1

2.11e-044572MP:0000461
DomainPeptidase_S9

PREPL DPP10

2.07e-0511122PF00326
DomainPeptidase_S9

PREPL DPP10

2.07e-0511122IPR001375
Domainzf-C2H2_6

ZNF700 ZNF763 ZNF69 ZNF440

3.49e-05314124PF13912
DomainKRAB

ZNF700 ZNF763 ZNF69 ZNF440

5.82e-05358124PS50805
DomainKRAB

ZNF700 ZNF763 ZNF69 ZNF440

5.82e-05358124PF01352
DomainKRAB

ZNF700 ZNF763 ZNF69 ZNF440

6.54e-05369124SM00349
DomainKRAB

ZNF700 ZNF763 ZNF69 ZNF440

6.61e-05370124IPR001909
Domain-

ZNF700 ZNF763 ZNF69 ZNF440

6.79e-046791243.30.160.60
Domainzf-C2H2

ZNF700 ZNF763 ZNF69 ZNF440

7.33e-04693124PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF700 ZNF763 ZNF69 ZNF440

7.37e-04694124IPR013087
DomainZINC_FINGER_C2H2_2

ZNF700 ZNF763 ZNF69 ZNF440

1.11e-03775124PS50157
DomainZINC_FINGER_C2H2_1

ZNF700 ZNF763 ZNF69 ZNF440

1.13e-03777124PS00028
DomainZnf_C2H2-like

ZNF700 ZNF763 ZNF69 ZNF440

1.23e-03796124IPR015880
DomainZnf_C2H2

ZNF700 ZNF763 ZNF69 ZNF440

1.28e-03805124IPR007087
DomainZnF_C2H2

ZNF700 ZNF763 ZNF69 ZNF440

1.30e-03808124SM00355
Domain-

PREPL DPP10

2.55e-031191223.40.50.1820
DomainAB_hydrolase

PREPL DPP10

2.55e-03119122IPR029058
DomainARM-type_fold

STAG1 PIK3CB

1.92e-02339122IPR016024
InteractionZNF763 interactions

ZNF763 ZNF69

4.87e-066122int:ZNF763
InteractionZNF69 interactions

ZNF763 ZNF69

4.40e-0517122int:ZNF69
Cytoband19p13.2

ZNF700 ZNF763 ZNF69 ZNF440

4.16e-0722913419p13.2
Cytoband3q22.3

STAG1 PIK3CB

2.21e-05251323q22.3
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ZNF700 ZNF763 ZNF69 ZNF440

5.69e-05797134chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr3q22

STAG1 PIK3CB

6.55e-04135132chr3q22
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF700 ZNF763 ZNF69 ZNF440

9.46e-0471812428
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Papillary-5|TCGA-Stomach / Sample_Type by Project: Shred V9

ZNF763 ZNF69 ZNF440

4.11e-06111133eb737146969b70c619649f244998d4183237c763
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Pleomorphic_Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ZNF700 ZNF763

3.75e-04100132c58e62e0086802f2f20b4def9d49ca8d3f1fba92
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Papillary|TCGA-Stomach / Sample_Type by Project: Shred V9

ZNF763 ZNF69

4.96e-04115132f02675a5ee12cb35535f82433d7f3f3e8349a677
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTSL1 DPP10

8.19e-04148132d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTSL1 DPP10

9.44e-041591325335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

PIK3CB LASP1

9.44e-04159132655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellCD8+_Memory_T_cell-RSV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ZNF69 ZNF440

9.67e-04161132f6d04f67da3557e80f13ef27bfabb94dcd80db2f
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAG1 PIK3CB

1.00e-03164132b895674ed2df87db8fbfb30b7e31620945588491
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 DPP10

1.05e-03168132e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 DPP10

1.05e-03168132b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CB LASP1

1.10e-03172132d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.12e-0317313295c723b09254ae7131fe5ba0841472502e83269b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.15e-0317613272a2a01618ce836bc843395d5095e9090759b4a6
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3CB DPP10

1.15e-0317613233323c97afe509147956b8df9f92ca6b0537e604
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 DPP10

1.15e-03176132c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDK17 LASP1

1.17e-0317713284930899eb2978598bc8a351cbcd9e714e46799d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.18e-03178132431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 DPP10

1.19e-03179132e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.19e-0317913253e700494d251ec5649b2dea5fc7d5aeeeed572b
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL1 DPP10

1.21e-03180132b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF69 PREPL

1.21e-0318013281d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.21e-03180132e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.23e-0318213272e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 DPP10

1.23e-0318213205c167158815bf25d509df59ab386e1990712765
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

STAG1 ADAMTSL1

1.27e-031851326814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

ZNF69 CDK17

1.29e-03186132701eea0016d69f0f9d29b613948f91239096e6c7
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

CDK17 ADAMTSL1

1.33e-0318913275c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

CDK17 ADAMTSL1

1.33e-03189132c81787a8c662db5d7814c583dd64562857629e81
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.34e-03190132048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL1 DPP10

1.34e-03190132a9a705455019e28d655636de73b07540798f82e6
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL1 DPP10

1.34e-0319013240d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL1 DPP10

1.34e-03190132f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.34e-031901321121eb607a984c59fbffe7220837fc178745aa55
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL1 DPP10

1.36e-0319113223776c7302cead3881b39127398f3b3e0d27885e
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 DPP10

1.38e-031931324ccf984baebbb13ae916727137ce593fda7514a2
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 DPP10

1.38e-03193132f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.38e-031931321f978e102a029a6beb10913052cd0a20c7253e8e
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

ZNF69 DPP10

1.40e-031941325759c83308df017f1faae248e9b85388e25254f0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDK17 PREPL

1.41e-03195132ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL1 DPP10

1.41e-03195132dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.41e-03195132818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.43e-03196132e224338490691d92c1f70b57112fabdcc92b06a9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.44e-03197132c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 ADAMTSL1

1.44e-031971322844dbcd0a673ed81c99920aa45858651a00736d
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 DPP10

1.47e-03199132bb201deb281619113edcd1de2af2d3eb21b967b8
DiseasePremature atrial contractions

ZNF700 ZNF69 ZNF440 DPP10

7.63e-0955134HP_0006699
Diseaseattempted suicide

ADAMTSL1 DPP10

2.70e-03178132EFO_0004321
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

ADAMTSL1 DPP10

3.95e-03216132EFO_0007925, EFO_0007927
DiseaseR-warfarin measurement

STAG1 ADAMTSL1

5.87e-03265132EFO_0803324
Diseasedaytime rest measurement

PREPL DPP10

7.22e-03295132EFO_0007828

Protein segments in the cluster

PeptideGeneStartEntry
EKGYNPPYCQPKQGA

ADAM5

376

Q6NVV9
GALYPKGKQYPYPKA

DPP10

271

Q8N608
KGKQYPYPKAGQVNP

DPP10

276

Q8N608
GYEKKPYCNAHYPKQ

LASP1

46

Q14847
QYCHYYPENIKPKPK

ADAMTSL1

336

Q8N6G6
YCYTSPGPPKKKKKY

HMGXB3

21

Q12766
EFKNYNFPKYKPQPL

CDK17

421

Q00537
PENKKQPYYYPPFDK

PIK3CB

496

P42338
YQEYGPKPCKCQQPK

ZNF440

136

Q8IYI8
YQEYGPKPYKCQQPK

ZNF700

156

Q9H0M5
FKYQNQKGQEYPPPN

STAG1

986

Q8WVM7
KRYCPYQNIKPQHYP

PREPL

621

Q4J6C6
YQEYGPKPCKCQQPK

ZNF69

156

Q9UC07
YQDYAPKPYKCQQPK

ZNF763

136

Q0D2J5
PKPYKCQQPKKAFRY

ZNF763

141

Q0D2J5