Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ4 DAZ1 DAZ3 DAZ2

4.22e-0715864GO:0008494
GeneOntologyMolecularFunctionnitrate reductase activity

MTARC2 MTARC1

5.48e-053862GO:0008940
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain phosphoserine binding

SCAF8 SCAF4

1.82e-045862GO:1990269
GeneOntologyMolecularFunctionmRNA 3'-UTR binding

TARDBP DAZ4 RBMS1 ELAVL1 DAZ1 DAZ3 DAZ2

1.89e-04276867GO:0003730
GeneOntologyMolecularFunctionmolybdenum ion binding

MTARC2 MTARC1

2.72e-046862GO:0030151
GeneOntologyMolecularFunctionmolybdopterin cofactor binding

MTARC2 MTARC1

2.72e-046862GO:0043546
GeneOntologyMolecularFunctionsingle-stranded DNA binding

MMS22L RBMS1 RECQL DHX9 WDR48

2.85e-04134865GO:0003697
GeneOntologyMolecularFunctionRNA polymerase II complex binding

SCAF8 SCAF4 DHX9

6.30e-0439863GO:0000993
GeneOntologyMolecularFunctionmRNA binding

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

7.90e-046948610GO:0003729
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC41A3 KCNQ2 PANX1 SLC9C2 CNGA1 ATP2B4 KCNH3 ITPR2

8.83e-04465868GO:0046873
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

SCAF8 SCAF4 DHX9

9.60e-0445863GO:0043175
GeneOntologyMolecularFunctionnitrite reductase activity

MTARC2 MTARC1

9.83e-0411862GO:0098809
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain binding

SCAF8 SCAF4

9.83e-0411862GO:0099122
GeneOntologyMolecularFunctionphosphoserine residue binding

SCAF8 SCAF4

1.18e-0312862GO:0050815
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

DAZ4 DAZ1 DAZ3 DAZ2

1.40e-03112864GO:0090079
GeneOntologyMolecularFunctionpre-mRNA intronic binding

TARDBP EP300

1.61e-0314862GO:0097157
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

SEPTIN8 ATAD1 SMARCA4 MFN2 DHX57 RECQL GNAO1 ATP2B4 MFN1 DHX9

1.81e-037758610GO:0017111
GeneOntologyMolecularFunction3'-5' DNA helicase activity

RECQL DHX9

2.12e-0316862GO:0043138
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BPTF SMARCA4 RECQL DHX9

2.22e-03127864GO:0008094
GeneOntologyMolecularFunctionoxidoreductase activity, acting on other nitrogenous compounds as donors

MTARC2 MTARC1

2.39e-0317862GO:0016661
GeneOntologyMolecularFunctionRNA polymerase binding

SCAF8 SCAF4 DHX9

2.78e-0365863GO:0070063
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

SEPTIN8 ADSS2 SLC19A1 MFN2 GNAO1 CNGA1 MFN1

2.86e-03439867GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

SEPTIN8 ADSS2 SLC19A1 MFN2 GNAO1 CNGA1 MFN1

2.86e-03439867GO:0019001
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

SCAF8 SCAF4 DHX9

2.90e-0366863GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

SCAF8 SCAF4 DHX9

2.90e-0366863GO:0001098
GeneOntologyMolecularFunctionpyrophosphatase activity

SEPTIN8 ATAD1 SMARCA4 MFN2 DHX57 RECQL GNAO1 ATP2B4 MFN1 DHX9

3.21e-038398610GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

SEPTIN8 ATAD1 SMARCA4 MFN2 DHX57 RECQL GNAO1 ATP2B4 MFN1 DHX9

3.24e-038408610GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SEPTIN8 ATAD1 SMARCA4 MFN2 DHX57 RECQL GNAO1 ATP2B4 MFN1 DHX9

3.24e-038408610GO:0016818
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

PANX1 CNGA1 ATP2B4 ITPR2

4.13e-03151864GO:0015085
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC19A1 PANX1

4.37e-0323862GO:0005346
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2

2.98e-0931866GO:0070935
GeneOntologyBiologicalProcessfemale meiosis II

DAZ4 DAZ1 DAZ3 DAZ2

4.20e-096864GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ4 DAZ1 DAZ3 DAZ2

4.20e-096864GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ4 DAZ1 DAZ3 DAZ2

4.20e-096864GO:0061983
GeneOntologyBiologicalProcessmRNA stabilization

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

3.25e-0877867GO:0048255
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

7.63e-0887867GO:1902373
GeneOntologyBiologicalProcessRNA stabilization

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

8.26e-0888867GO:0043489
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

2.14e-07101867GO:1902369
GeneOntologyBiologicalProcesspositive regulation of translation

PASK DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 EP300 DHX9

2.24e-07151868GO:0045727
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

5.20e-07115867GO:1903312
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

3.93e-0626864GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

6.18e-0629864GO:0045948
GeneOntologyBiologicalProcesspositive regulation of reproductive process

IL18 DAZ4 MFN2 DAZ1 DAZ3 DAZ2

9.99e-06118866GO:2000243
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

1.67e-0537864GO:0051446
GeneOntologyBiologicalProcessnegative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

1.72e-052862GO:2000805
GeneOntologyBiologicalProcessnegative regulation of termination of RNA polymerase II transcription

SCAF8 SCAF4

1.72e-052862GO:0120191
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

3.68e-0545864GO:0040020
GeneOntologyBiologicalProcessregulation of translation

PASK PARP16 DAZ4 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 EP300 DHX9

3.94e-054948610GO:0006417
GeneOntologyBiologicalProcessoocyte maturation

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-0547864GO:0001556
GeneOntologyBiologicalProcessregulation of mRNA catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

4.46e-05309868GO:0061013
GeneOntologyBiologicalProcessnegative regulation of termination of DNA-templated transcription

SCAF8 SCAF4

5.14e-053862GO:0060567
GeneOntologyBiologicalProcesstermination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

5.14e-053862GO:0030846
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

5.14e-053862GO:2000804
GeneOntologyBiologicalProcessnegative regulation of catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 ATP2B4 EP300 DHX9

6.13e-05418869GO:0009895
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

6.55e-0552864GO:0007143
GeneOntologyBiologicalProcessviral gene expression

TARDBP PARP16 SMARCA4 EP300 DHX9

9.31e-05109865GO:0019080
GeneOntologyBiologicalProcessviral transcription

TARDBP SMARCA4 EP300 DHX9

1.01e-0458864GO:0019083
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription

SCAF8 SCAF4

1.03e-044862GO:1904594
GeneOntologyBiologicalProcessnitrate metabolic process

MTARC2 MTARC1

1.03e-044862GO:0042126
GeneOntologyBiologicalProcesscell maturation

DAZ4 TMEM79 KCNQ2 DAZ1 GRIP2 DAZ3 DAZ2

1.27e-04267867GO:0048469
GeneOntologyBiologicalProcesstranslation

PASK MRPL16 PARP16 DAZ4 ELAVL1 DAZ1 RPS21 RBM8A DAZ3 DAZ2 EP300 DHX9

1.54e-048248612GO:0006412
GeneOntologyBiologicalProcessmRNA catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

1.65e-04373868GO:0006402
GeneOntologyBiologicalProcesscellular detoxification of nitrogen compound

MTARC2 MTARC1

1.70e-045862GO:0070458
GeneOntologyBiologicalProcessdetoxification of nitrogen compound

MTARC2 MTARC1

1.70e-045862GO:0051410
GeneOntologyBiologicalProcessregulation of mRNA stability

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

2.19e-04292867GO:0043488
GeneOntologyBiologicalProcessanimal organ morphogenesis

FANCC SOX11 CRYGB FLT1 IL18 ADAMTS9 PSG5 SEC24B SMARCA4 MFN2 LAMB3 KDM2A EP300 JHY WDR48

2.21e-0412698615GO:0009887
GeneOntologyBiologicalProcessregulation of termination of DNA-templated transcription

SCAF8 SCAF4

2.55e-046862GO:0031554
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

2.73e-0475864GO:0051785
GeneOntologyBiologicalProcessregulation of RNA stability

TARDBP DAZ4 ELAVL1 DAZ1 DAZ3 DAZ2 DHX9

3.03e-04308867GO:0043487
GeneOntologyBiologicalProcessDNA-templated transcription termination

SCAF8 SCAF4 DHX9

3.81e-0434863GO:0006353
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

3.85e-0482864GO:0051445
GeneOntologyBiologicalProcessRNA catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

4.42e-04432868GO:0006401
GeneOntologyBiologicalProcessnegative regulation of mitochondrial fission

MFN2 MFN1

4.73e-048862GO:0090258
GeneOntologyBiologicalProcessoogenesis

DAZ4 DAZ1 PANX1 DAZ3 DAZ2

4.94e-04156865GO:0048477
GeneOntologyBiologicalProcessmeiotic nuclear division

DAZ4 CCNA1 DAZ1 EME2 DAZ3 DAZ2

5.04e-04240866GO:0140013
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

TARDBP DAZ4 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

5.22e-04443868GO:1903311
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

5.71e-0491864GO:0006446
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 RBM8A PFKL DAZ3 DAZ2 EP300 DHX9

6.30e-046968610GO:0034655
GeneOntologyBiologicalProcessregulation of reproductive process

IL18 DAZ4 MFN2 DAZ1 DAZ3 DAZ2

6.38e-04251866GO:2000241
GeneOntologyBiologicalProcessanatomical structure maturation

DAZ4 TMEM79 KCNQ2 DAZ1 GRIP2 DAZ3 DAZ2

6.95e-04354867GO:0071695
GeneOntologyBiologicalProcessnucleic acid catabolic process

TARDBP DAZ4 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

7.07e-04464868GO:0141188
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

SOX11 CRYGB FLT1 ADAMTS9 MFN2

7.48e-04171865GO:0048593
GeneOntologyBiologicalProcessoocyte development

DAZ4 DAZ1 DAZ3 DAZ2

7.84e-0499864GO:0048599
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

FLII SCAF8 SPTBN2 SCAF4

8.15e-04100864GO:0043242
GeneOntologyBiologicalProcessestablishment of planar polarity

SEC24B BRSK1 JHY

8.19e-0444863GO:0001736
GeneOntologyBiologicalProcesspositive regulation of gene expression

SOX11 PASK TARDBP IL18 DAZ4 SMARCA4 MFN2 ELAVL1 KDM2A DAZ1 PANX1 DAZ3 DAZ2 EP300 DHX9

8.73e-0414468615GO:0010628
GeneOntologyBiologicalProcessestablishment of tissue polarity

SEC24B BRSK1 JHY

8.75e-0445863GO:0007164
GeneOntologyBiologicalProcessmeiotic cell cycle process

DAZ4 CCNA1 DAZ1 EME2 DAZ3 DAZ2

8.97e-04268866GO:1903046
GeneOntologyBiologicalProcesslens development in camera-type eye

SOX11 CRYGB ADAMTS9 SMARCA4

9.10e-04103864GO:0002088
GeneOntologyBiologicalProcessoocyte differentiation

DAZ4 DAZ1 DAZ3 DAZ2

9.10e-04103864GO:0009994
GeneOntologyBiologicalProcessintracellular distribution of mitochondria

MFN2 MFN1

1.10e-0312862GO:0048312
GeneOntologyCellularComponentperichromatin fibrils

TARDBP SMARCA4 DHX9

3.84e-068873GO:0005726
MousePhenoabsent ovarian follicles

FANCC DAZ4 DAZ1 DAZ3 DAZ2

6.59e-0651735MP:0002777
DomainRRM_1

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

5.01e-082088810PF00076
DomainRRM

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

7.46e-082178810SM00360
DomainRRM_dom

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

1.14e-072278810IPR000504
DomainRRM

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

1.29e-072308810PS50102
Domain-

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

2.23e-0724488103.30.70.330
DomainNucleotide-bd_a/b_plait

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

3.73e-072588810IPR012677
DomainBromodomain_CS

BPTF BAZ1A SMARCA4 EP300

6.35e-0626884IPR018359
DomainMitofusin_fam

MFN2 MFN1

2.19e-052882IPR027094
DomainFzo_mitofusin

MFN2 MFN1

2.19e-052882PF04799
DomainFzo/mitofusin_HR2

MFN2 MFN1

2.19e-052882IPR006884
DomainBROMODOMAIN_1

BPTF BAZ1A SMARCA4 EP300

2.70e-0537884PS00633
DomainBromodomain

BPTF BAZ1A SMARCA4 EP300

3.00e-0538884PF00439
DomainBROMODOMAIN_2

BPTF BAZ1A SMARCA4 EP300

4.08e-0541884PS50014
DomainBROMO

BPTF BAZ1A SMARCA4 EP300

4.49e-0542884SM00297
DomainBromodomain

BPTF BAZ1A SMARCA4 EP300

4.49e-0542884IPR001487
Domain-

BPTF BAZ1A SMARCA4 EP300

4.49e-05428841.20.920.10
DomainMOSC

MTARC2 MTARC1

6.56e-053882PS51340
DomainMOSC

MTARC2 MTARC1

6.56e-053882PF03473
DomainMOSC_N

MTARC2 MTARC1

6.56e-053882PF03476
DomainMOSC_N

MTARC2 MTARC1

6.56e-053882IPR005303
DomainMoCF_Sase_C

MTARC2 MTARC1

6.56e-053882IPR005302
DomainDDT

BPTF BAZ1A

1.31e-044882PF02791
DomainDDT

BPTF BAZ1A

2.17e-045882SM00571
DomainWSD

BPTF BAZ1A

2.17e-045882PF15613
DomainWHIM1

BPTF BAZ1A

2.17e-045882PF15612
DomainDDT_dom

BPTF BAZ1A

2.17e-045882IPR018501
DomainPyrv_Knase-like_insert_dom

MTARC2 MTARC1

2.17e-045882IPR011037
DomainWHIM1_dom

BPTF BAZ1A

2.17e-045882IPR028942
DomainWHIM2_dom

BPTF BAZ1A

2.17e-045882IPR028941
DomainDDT

BPTF BAZ1A

3.25e-046882PS50827
DomainRNA_pol_II-bd

SCAF8 SCAF4

4.54e-047882IPR006903
DomainCTD_bind

SCAF8 SCAF4

4.54e-047882PF04818
DomainCNMP_BINDING_1

SLC9C2 CNGA1 KCNH3

4.54e-0432883PS00888
DomainCNMP_BINDING_2

SLC9C2 CNGA1 KCNH3

4.54e-0432883PS00889
DomaincNMP

SLC9C2 CNGA1 KCNH3

5.44e-0434883SM00100
DomaincNMP_binding

SLC9C2 CNGA1 KCNH3

5.44e-0434883PF00027
DomaincNMP-bd_dom

SLC9C2 CNGA1 KCNH3

5.93e-0435883IPR000595
DomainCNMP_BINDING_3

SLC9C2 CNGA1 KCNH3

5.93e-0435883PS50042
DomainRPR

SCAF8 SCAF4

6.03e-048882SM00582
DomainCID

SCAF8 SCAF4

6.03e-048882PS51391
DomainCID_dom

SCAF8 SCAF4

6.03e-048882IPR006569
DomaincNMP-bd-like

SLC9C2 CNGA1 KCNH3

7.57e-0438883IPR018490
DomainPAS_9

PASK KCNH3

9.64e-0410882PF13426
DomainHud_Sxl_RNA

RBMS1 ELAVL1

9.64e-0410882IPR002343
DomainPTBI

DOK6 DOK5

1.17e-0311882SM00310
DomainEGF_3

CUBN STAB1

1.40e-0312882PF12947
DomainEGF_dom

CUBN STAB1

1.40e-0312882IPR024731
DomainIRS_PTB

DOK6 DOK5

1.40e-0312882PS51064
Domain-

SLC9C2 CNGA1 KCNH3

1.50e-03488832.60.120.10
DomainHelicase_C

SMARCA4 DHX57 RECQL DHX9

1.64e-03107884PF00271
DomainHELICc

SMARCA4 DHX57 RECQL DHX9

1.64e-03107884SM00490
DomainHelicase_C

SMARCA4 DHX57 RECQL DHX9

1.70e-03108884IPR001650
DomainHELICASE_CTER

SMARCA4 DHX57 RECQL DHX9

1.76e-03109884PS51194
DomainHELICASE_ATP_BIND_1

SMARCA4 DHX57 RECQL DHX9

1.76e-03109884PS51192
DomainDEXDc

SMARCA4 DHX57 RECQL DHX9

1.76e-03109884SM00487
DomainRmlC-like_jellyroll

SLC9C2 CNGA1 KCNH3

1.79e-0351883IPR014710
DomainHelicase_ATP-bd

SMARCA4 DHX57 RECQL DHX9

1.82e-03110884IPR014001
DomainGelsolin

FLII SEC24B

1.93e-0314882PF00626
DomainIRS_PTB

DOK6 DOK5

1.93e-0314882IPR002404
DomainMORN

ANKMY1 JPH3

1.93e-0314882SM00698
DomainK_chnl_volt-dep_EAG/ELK/ERG

CNGA1 KCNH3

1.93e-0314882IPR003938
DomainG_DYNAMIN_dom

MFN2 MFN1

1.93e-0314882IPR030381
DomainGelsolin-like_dom

FLII SEC24B

1.93e-0314882IPR007123
DomainIRS

DOK6 DOK5

1.93e-0314882PF02174
DomainG_DYNAMIN_2

MFN2 MFN1

1.93e-0314882PS51718
DomainIon_trans_dom

KCNQ2 CNGA1 KCNH3 ITPR2

2.07e-03114884IPR005821
DomainIon_trans

KCNQ2 CNGA1 KCNH3 ITPR2

2.07e-03114884PF00520
DomainMORN

ANKMY1 JPH3

2.21e-0315882IPR003409
DomainDynamin_GTPase

MFN2 MFN1

2.21e-0315882IPR001401
DomainDynamin_N

MFN2 MFN1

2.21e-0315882PF00350
DomainMORN

ANKMY1 JPH3

2.21e-0315882PF02493
DomainDynamin_SF

MFN2 MFN1

2.21e-0315882IPR022812
DomainDUF1605

DHX57 DHX9

2.85e-0317882IPR011709
DomainOB_NTP_bind

DHX57 DHX9

2.85e-0317882PF07717
DomainHA2

DHX57 DHX9

3.20e-0318882SM00847
DomainHA2

DHX57 DHX9

3.20e-0318882PF04408
DomainHelicase-assoc_dom

DHX57 DHX9

3.20e-0318882IPR007502
DomainZinc_finger_PHD-type_CS

BPTF BAZ1A KDM2A

3.58e-0365883IPR019786
DomainSRCR

CD163L1 SCARA5

4.35e-0321882PF00530
PathwayWP_MALE_INFERTILITY

DAZ4 CCNA1 DAZ1 GNAO1 DAZ3 DAZ2 EP300

9.74e-06145737M39856
PathwayWP_OVARIAN_INFERTILITY

DAZ4 DAZ1 DAZ3 DAZ2

3.07e-0535734MM15948
PathwayWP_MRNA_PROCESSING

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 DHX9

1.04e-044517310MM15946
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

DAZ4 SMARCA4 DAZ1 CUBN DAZ3 DAZ2 EP300 DHX9

1.59e-04301738MM15983
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

FANCC DAZ4 DAZ1 DAZ3 DAZ2

5.14e-12888510951504
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-1148847670487
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488411694340
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-1148849321470
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488419223287
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488426232607
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488411688365
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488412752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488411883873
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488412801575
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488415066457
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488411095434
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488410936047
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ4 DAZ1 DAZ3 DAZ2

3.83e-11488416963411
Pubmed

Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility.

DAZ4 DAZ1 DAZ3 DAZ2 MFN1

7.22e-111288538088064
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588423579190
Pubmed

The dazzle in germ cell differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588420008336
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058848679003
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588417416365
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588422293198
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588411089564
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588410393944
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058848968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058848968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588430380414
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588426411291
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588434985827
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588414648873
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058848896558
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058849700189
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588422021443
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058849288969
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588423456578
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588410903443
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058849143498
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588422699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058848845845
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588411058556
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588419783541
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588417761180
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588419468308
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588412200456
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588411514340
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588423298641
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588422223682
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588423223451
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588411804965
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-10588421270429
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ4 DAZ1 DAZ3 DAZ2

1.91e-1058848661148
Pubmed

Mouse models of male infertility.

FANCC DAZ4 DAZ1 DAZ3 DAZ2

5.58e-101788512360237
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688418452650
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688424086306
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688419247806
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688431355046
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688420157580
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688428496037
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688426077710
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688417526644
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-1068841638086
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688414611632
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688415066460
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688423417416
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688432170089
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688416278232
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688417219433
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688416001084
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688432962040
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-1068841869307
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688411390979
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ4 DAZ1 DAZ3 DAZ2

5.72e-10688427632217
Pubmed

Meioc maintains an extended meiotic prophase I in mice.

DAZ4 CCNA1 DAZ1 DAZ3 DAZ2

1.05e-091988528380054
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788415081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788422699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788411604102
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788416946704
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788410857750
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788411410654
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-0978849588208
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-09788426826184
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4 DHX9

1.34e-09347881116033648
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888423204224
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888429883445
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888410823932
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888411869379
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888432339196
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888433749946
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888422621333
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ4 DAZ1 DAZ3 DAZ2

2.66e-09888432686646
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ4 DAZ1 DAZ3 DAZ2

4.77e-09988416310179
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ4 DAZ1 DAZ3 DAZ2

4.77e-09988426378784
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

4.77e-09988419695304
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

4.77e-09988428235998
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

4.77e-09988420159962
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-091088431234534
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-091088414648882
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-091088438433229
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-091088423810942
Pubmed

The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-091088412837688
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-091088410601091
Pubmed

Knockout mouse model and gametogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

7.94e-09108849922113
CytobandYq11.223

DAZ4 DAZ1 DAZ3 DAZ2

3.23e-0593884Yq11.223
Cytoband20q13.3

KCNQ2 RPS21

6.75e-042088220q13.3
GeneFamilyRNA binding motif containing

TARDBP SCAF8 DAZ4 RBMS1 ELAVL1 DAZ1 RBM8A DAZ3 DAZ2 SCAF4

2.63e-092136210725
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CD163L1 SCARA5 STAB1

1.06e-04276231253
GeneFamilyDEAH-box helicases

DHX57 DHX9

1.35e-0316622500
GeneFamilyPHD finger proteins

BPTF BAZ1A KDM2A

3.65e-039062388
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

DAZ4 DAZ1 DAZ3 DAZ2

5.75e-0812884MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ4 DAZ1 DAZ3 DAZ2

5.75e-0812884MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ4 DAZ1 DAZ3 DAZ2

1.00e-0623884MM1293
CoexpressionMATZUK_SPERMATOGONIA

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-0631884MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ4 DAZ1 DAZ3 DAZ2

4.51e-0633884MM701
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 VSTM2L SPTBN2 BRSK1 KCNH3 JPH3

1.46e-06178886a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 VSTM2L SPTBN2 BRSK1 KCNH3 JPH3

1.46e-061788861bddbc083c36657bd6910f7466126ab325e88176
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 VSTM2L SPTBN2 KCNQ2 BRSK1 KCNH3

1.51e-06179886a3922476f33d2e4137a12dbda21a1703dff79684
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

IL18 BAIAP2L1 SPTBN2 GRIP2 FBN3 ITPR2

1.71e-061838865c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CD163L1 GPRIN3 KDM2A SCAF4 ITPR2 STAB1

1.94e-061878860099def970fbc828756fbf853eca2ce77b8cd342
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 SPTBN2 GPRIN3 FBN3 ITPR2

1.65e-05160885174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 SPTBN2 GRIP2 FBN3 ITPR2

2.40e-051738850bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 GPRIN3 GRIP2 FBN3 ITPR2

2.61e-05176885c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

PCNX2 SLC41A3 SMARCA4 DHX57 GPRIN3

2.83e-051798859d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|COVID-19_Convalescent / Disease condition and Cell class

PCNX2 SLC41A3 SMARCA4 DHX57 GPRIN3

2.83e-05179885366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 BAIAP2L1 SPTBN2 KCNQ2 FBN3

2.83e-0517988527ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOK5 VSTM2L SPTBN2 GNAO1 JHY

3.22e-051848853e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOK5 VSTM2L SPTBN2 GNAO1 JHY

3.22e-051848851e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT1 CD163L1 SCARA5 GRIP2 FBN3

3.31e-051858850b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 BAIAP2L1 SPTBN2 FBN3 ITPR2

3.40e-05186885a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 SPTBN2 KCNQ2 ATP2B4 KCNH3

3.40e-051868857278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 BAIAP2L1 SPTBN2 FBN3 ITPR2

3.57e-05188885e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

VSTM2L SPTBN2 KCNQ2 GPRIN3 JPH3

3.95e-051928854c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 SPTBN2 KCNQ2 ATP2B4 KCNH3

4.05e-05193885be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 SPTBN2 KCNQ2 ATP2B4 KCNH3

4.05e-051938850c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 SPTBN2 KCNQ2 ATP2B4 KCNH3

4.05e-051938858689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

FLT1 CD163L1 SCARA5 GRIP2 FBN3

4.79e-05200885501a3b93624df463458a35d3e6648d4ccc941724
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

FLT1 CD163L1 SCARA5 GRIP2 FBN3

4.79e-05200885d1f36a8232411933b1494168ec912fd0e5246428
Drugboron trichloride

DAZ4 DAZ1 DAZ3 DAZ2

3.11e-096884CID000025135
DrugVistar

DAZ4 DAZ1 DAZ3 DAZ2 CAPN15

2.64e-0736885CID000040896
Drugdesmethylazelastine

DAZ4 DAZ1 DAZ3 DAZ2

3.66e-0716884CID000162558
Drugpropham

DAZ4 RBMS1 DAZ1 DAZ3 DAZ2

7.41e-0744885CID000024685
Drugdazmegrel

DAZ4 DAZ1 DAZ3 DAZ2

7.72e-0719884CID000053555
DrugYM 026

DAZ4 DAZ1 DAZ3 DAZ2

7.72e-0719884CID000004443
DrugMometasone furoate [83919-23-7]; Down 200; 7.6uM; HL60; HG-U133A

PASK ELAVL1 KDM2A MAP2K5 ATP2B4 CAPN15 DHX9 WDR48

9.69e-071978881746_DN
DrugAZFd

DAZ4 DAZ1 DAZ3 DAZ2

1.74e-0623884CID000196489
Drugdansylaziridine

DAZ4 DAZ1 DAZ3 DAZ2

1.74e-0623884CID000104008
Drugbipy

FANCC ACLY DAZ4 DAZ1 DAZ3 DAZ2

2.09e-0697886CID000001474
Drugd-gluconhydroximo-1,5-lactam

DAZ4 DAZ1 DAZ3 DAZ2

6.05e-0631884CID000003479
Drug3-bromo-7-nitroindazole

DAZ4 DAZ1 DAZ3 DAZ2

1.12e-0536884CID000001649
DrugRepaglinide [135062-02-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

PARP16 SLC19A1 MFN2 LAMB3 KDM2A SCAF4 WDR48

1.18e-051988877216_DN
DrugSulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A

SMARCA4 MTARC2 MAP2K5 ATP2B4 MFN1 SCAF4 WDR48

1.18e-051988871688_UP
DrugAdamantamine fumarate [80789-67-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A

FLII ZFAND3 SLC41A3 LAMB3 MTARC2 MAP2K5 JHY

1.22e-051998873280_UP
Drug4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid

SLC19A1 PANX1

1.48e-052882ctd:D012856
Drugmolybdenum disulfide

DAZ4 DAZ1 DAZ3 DAZ2

2.29e-0543884CID000014823
Drug2-chlorodideoxyadenosine

DAZ4 DAZ1 DAZ3 DAZ2

2.29e-0543884CID000072194
Drugridogrel

DAZ4 DAZ1 DAZ3 DAZ2

4.90e-0552884CID005362391
Drugazafagomine

DAZ4 DAZ1 DAZ3 DAZ2

7.04e-0557884CID011957435
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

BPTF BAZ1A SCAF8 RBMS1 SEC24B MFN1

7.80e-051838867498_DN
DrugN(4)-hydroxycytosine

MTARC2 MTARC1

8.82e-054882ctd:C021202
DrugN(4)-hydroxycytidine

MTARC2 MTARC1

8.82e-054882ctd:C010737
DrugNSC56408

DAZ4 DAZ1 DAZ3 DAZ2

9.79e-0562884CID000005604
DrugTiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; HL60; HG-U133A

TARDBP BAZ1A SLC19A1 RECQL MAP2K5 WDR48

1.04e-041938861412_DN
DrugEtodolac [41340-25-4]; Down 200; 14uM; PC3; HT_HG-U133A

FANCC SLC41A3 MFN2 KDM2A CAPN15 DHX9

1.07e-041948862091_DN
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

FANCC SEPTIN8 PARP16 SLC19A1 MTARC1 SCAF4

1.11e-04195886999_DN
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

SEPTIN8 KDM2A ANKMY1 ATP2B4 ITPR2 STAB1

1.11e-041958866176_UP
DrugTiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A

PASK FLII SLC19A1 MAP2K5 MFN1 DHX9

1.11e-041958863663_DN
DrugLevamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; HL60; HG-U133A

FLII IL18 DHX57 ANKMY1 AGBL5 MAP2K5

1.11e-041958861410_UP
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A

FANCC FLII SLC19A1 ACLY ANKMY1 CAPN15

1.14e-041968864645_DN
DrugMephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A

PCNX2 SLC41A3 MFN2 RECQL MAP2K5 WDR48

1.17e-041978866275_DN
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

SEPTIN8 PARP16 MTARC2 AGBL5 CAPN15 WDR48

1.17e-041978866930_DN
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; HL60; HG-U133A

FLII CCNA1 SMARCA4 MFN2 CAPN15 WDR48

1.17e-041978861602_DN
DrugTremorine dihydrochloride [300-68-5]; Up 200; 15uM; HL60; HG-U133A

SLC19A1 SMARCA4 RPS21 EP300 STAB1 WDR48

1.20e-041988861579_UP
DrugMinoxidil [38304-91-5]; Up 200; 19.2uM; HL60; HG-U133A

PARP16 SLC19A1 RECQL RBM8A MAP2K5 WDR48

1.24e-041998861996_UP
Drug(+/-)-thalidomide; Up 200; 100uM; MCF7; HG-U133A

DOK5 SPTBN2 KCNQ2 MTARC1 JHY WDR48

1.24e-04199886606_UP
DrugAcetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A

FANCC PARP16 SMARCA4 AGBL5 SCAF4 ITPR2

1.24e-041998862769_DN
DrugMafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A

FANCC PCNX2 SPTBN2 LAMB3 MAP2K5 ITPR2

1.24e-041998862287_DN
Drugkt S

DAZ4 DAZ1 DAZ3 DAZ2

1.25e-0466884CID006399216
DiseaseMale sterility due to Y-chromosome deletions

DAZ4 DAZ1 DAZ3 DAZ2

4.67e-098864C2931163
DiseasePartial chromosome Y deletion

DAZ4 DAZ1 DAZ3 DAZ2

4.67e-098864C1507149
DiseaseCharcot-Marie-Tooth disease type 2A2A (implicated_via_orthology)

MFN2 MFN1

8.40e-062862DOID:0110155 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease type 2A2B (implicated_via_orthology)

MFN2 MFN1

8.40e-062862DOID:0111557 (implicated_via_orthology)
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ3 DAZ2

1.30e-0516863C1839071
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ3 DAZ2

1.30e-0516863cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ3 DAZ2

1.30e-0516863415000
DiseaseCharcot-Marie-Tooth disease type 2 (implicated_via_orthology)

MFN2 MFN1

5.02e-054862DOID:0050539 (implicated_via_orthology)
DiseaseL lactate dehydrogenase measurement

CD163L1 GNAO1 STAB1

5.92e-0526863EFO_0004808
DiseaseAmphetamine-Related Disorders

MTARC2 CUBN MAP2K5 MTARC1

6.98e-0575864C0236733
DiseaseAmphetamine Abuse

MTARC2 CUBN MAP2K5 MTARC1

6.98e-0575864C0236807
DiseaseAmphetamine Addiction

MTARC2 CUBN MAP2K5 MTARC1

6.98e-0575864C0236804
Diseasepreeclampsia, fetal genotype effect measurement

FLT1 ITPR2

8.35e-055862EFO_0000668, EFO_0007959
DiseaseColorectal Carcinoma

ATAD1 SLC19A1 SPTBN2 LAMB3 KDM2A CUBN EP300 MFN1 JPH3

2.09e-04702869C0009402
Diseaseprimary pulmonary hypertension (is_marker_for)

MFN2 MFN1

2.32e-048862DOID:14557 (is_marker_for)
Diseaseresponse to bupropion

BAZ1A GPRIN3

2.98e-049862EFO_0006326
DiseaseC-C motif chemokine 25 measurement

ELAVL1 FBN3

2.98e-049862EFO_0008050
DiseaseAntithrombotic agent use measurement

FANCC FLT1 SMARCA4

5.62e-0455863EFO_0009925
DiseaseCoffin-Siris syndrome

SOX11 SMARCA4

6.41e-0413862C0265338
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

KCNQ2 GNAO1

6.41e-0413862DOID:0112202 (implicated_via_orthology)
DiseaseKawasaki disease (is_marker_for)

FLT1 IL18

7.47e-0414862DOID:13378 (is_marker_for)
Diseasetrimethylamine-N-oxide measurement

CUBN ITPR2

7.47e-0414862EFO_0010541
DiseaseBladder Neoplasm

FANCC BPTF SLC19A1 EP300

7.63e-04140864C0005695
DiseaseMalignant neoplasm of urinary bladder

FANCC BPTF SLC19A1 EP300

7.83e-04141864C0005684
Diseasemelanoma

FLT1 CD163L1 ECHDC1 CUBN EP300

8.06e-04248865C0025202
DiseaseAlzheimer's disease (is_marker_for)

BPTF TARDBP MFN2 EP300 MFN1

9.45e-04257865DOID:10652 (is_marker_for)
Diseasesyndrome (implicated_via_orthology)

SCAF8 SCAF4

1.25e-0318862DOID:225 (implicated_via_orthology)
Diseasefactor VIII measurement, Ischemic stroke

SCARA5 JPH3

1.39e-0319862EFO_0004630, HP_0002140
Diseasesusceptibility to scarlet fever measurement

SEC24B GNAO1 JPH3

1.61e-0379863EFO_0008409
DiseaseCardiomegaly

IL18 MFN2 ITPR2

1.79e-0382863C0018800
DiseaseCardiac Hypertrophy

IL18 MFN2 ITPR2

1.79e-0382863C1383860
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MFN2 MFN1

2.22e-0324862DOID:10595 (implicated_via_orthology)
Diseasemetabolic syndrome

BPTF SMARCA4 GNAO1 WDR48

2.82e-03200864EFO_0000195

Protein segments in the cluster

PeptideGeneStartEntry
MELRCGGLLFSSRFD

AGBL5

1

Q8NDL9
CDLMDGRDAFLTLAR

EP300

1621

Q09472
EETGEMFRVANCRGD

ANKRD60

101

Q9BZ19
ICSDASDMELRLVGG

CD163L1

681

Q9NR16
ARGFARMTGVTCDDV

FBN3

856

Q75N90
YTLREDGAMCRDVDE

FBN3

2196

Q75N90
GYTAEGRDVDECRML

FBN3

2356

Q75N90
SRAMDFEGKLGCDSE

BPTF

1396

Q12830
GIDARMDETEIGSCF

DAZ2

46

Q13117
GIDARMDETEIGSCF

DAZ3

46

Q9NR90
ESREGDFGCTVMELR

ATP2B4

16

P23634
RGGFDATDDACMELR

BAZ1A

576

Q9NRL2
AFSGCLDLLEADMRR

RGS9BP

81

Q6ZS82
GSEEGSRARMREDYD

RBM8A

41

Q9Y5S9
RGVGFARMESTEKCE

RBMS1

181

P29558
EGSDARIRCGAFMSK

ITPR2

1641

Q14571
DLTGFSRAEVMQRGC

KCNH3

51

Q9ULD8
DGMGRNLADRCTDEV

MFN1

451

Q8IWA4
ESRGERHEGREGMTC

CAPN15

961

O75808
MEDGGLTAFEEDQRC

PASK

1

Q96RG2
YLGAECRTVREEMGD

FLII

571

Q13045
EAECTAMGLRSGNLR

MTARC1

76

Q5VT66
CHSEFDDRIRGNGME

JHY

56

Q6NUN7
GGAEFTTACDFRLMT

ECHDC1

161

Q9NTX5
DGFSMLLRACRESEL

MMS22L

651

Q6ZRQ5
RSMGVLSDSEARCGD

C9orf131

576

Q5VYM1
AEGCSLDGLAREEMD

NHSL1

1551

Q5SYE7
GVVCRRASQEDMGLD

PCNX2

2111

A6NKB5
ASMEFLRQEDTPGCR

KCNQ2

761

O43526
RISICTEFMDGGSLD

MAP2K5

236

Q13163
NFMCERLGETRSRGS

PFKL

241

P17858
MCETGEGLFIFQTRD

DOK5

201

Q9P104
EDHMAEDCRGDIGRT

ELAVL1

6

Q15717
AAKSARDLDMRDGAC

PANX1

156

Q96RD7
EEGLGRNMSDRCSTA

MFN2

471

O95140
RDRDSGDNGKMVCSI

PCDHB12

371

Q9Y5F1
EAAGRDMLAADLRCS

PARP16

11

Q8N5Y8
FRLRFESSMEECGGD

CUBN

2441

O60494
FGEDRLNDRMCDPET

ADAMTS9

1081

Q9P2N4
GTMRRRYEDDGISDD

KDM2A

16

Q9Y2K7
ECLSMGAAADRRADS

BAIAP2L1

441

Q9UHR4
GIDARMDETEIGSCF

DAZ1

46

Q9NQZ3
GIDARMDETEIGSCF

DAZ1

211

Q9NQZ3
GIDARMDETEIGSCF

DAZ1

376

Q9NQZ3
MCDTGEGLFTFQTRE

DOK6

201

Q6PKX4
GIGSDERFRQCLMSD

FNIP1

1016

Q8TF40
AVLRMCDGDVGASLE

DHX57

201

Q6P158
DRDSCSVREGMAFED

CCNA1

146

P78396
EMFRCALLETDGALE

FANCC

296

Q00597
EGGRTALHMACERED

ANKMY1

656

Q9P2S6
RDELRGQMSELTDDC

CRYGB

96

P07316
ESMASLGCFRDRERL

BRSK1

321

Q8TDC3
AECTAMGLRSGNLRD

MTARC2

76

Q969Z3
LGSRRDMPCDEESGR

LAMB3

436

Q13751
EACSTERERMGLLAD

EME2

326

A4GXA9
GIDARMDETEIGSCF

DAZ4

46

Q86SG3
GIDARMDETEIGSCF

DAZ4

211

Q86SG3
GERQGAICDSEMRSC

GPRIN3

221

Q6ZVF9
RMFGEALEDLESCGQ

GRIP2

871

Q9C0E4
GNRPLFEDMTDSDCR

IL18

61

Q14116
EKLTREGAFLMDCGS

SEC24B

1151

O95487
ELESFCEGGMLDSDT

SCAF4

611

O95104
DRDDRDFDFCREMNG

SCAF8

1161

Q9UPN6
EDEALMLRDGRFACA

SCNM1

31

Q9BWG6
DGDVVCRMLGFRGVE

SCARA5

426

Q6ZMJ2
DDARMGGEEAEIRFC

DHX9

926

Q08211
MRGSCERSGEDEEQK

LRRC74B

1

Q6ZQY2
AGRLVVEMGGRCEFE

MRPL16

156

Q9NX20
REALDTEEGEFMACS

SOX11

16

P35716
CGAIRRMGESDDSIL

RPS21

56

P63220
GRCTEDMTEDELREF

TARDBP

196

Q13148
MGCTLSAEERAALER

GNAO1

1

P09471
RLTCEEEEEKMFGRG

SMARCA4

1356

P51532
DGGLRFGEMERDCQI

POLR2B

1081

P30876
MDGTETRQRRLDSCG

SLC41A3

1

Q96GZ6
RSGLRMCDLVSDFDG

ADSS2

176

P30520
MLRNCGSFTREEADE

ACLY

1036

P53396
TDGFSGSDLKEMCRD

ATAD1

291

Q8NBU5
EIRRMENGACSSFSE

CNGA1

26

P29973
ESGRAGRDDMKADCI

RECQL

401

P46063
FRLLCRDSGGETESM

WDR48

526

Q8TAF3
IEARADRFSSCIDMG

SPTBN2

1956

O15020
DRGRCETSASELERM

SLC19A1

216

P41440
IVRCEAGEGECRTFM

TMEM79

146

Q9BSE2
MEDERSFSDICGGRL

PIGH

1

Q14442
RRCKLEEMGFQDSDG

SEPTIN8

301

Q92599
FSCSRTRAGELMVGE

STAB1

1826

Q9NY15
RGSRDMFTEFCTTGD

SLC9C2

931

Q5TAH2
TEMRVCGGNEFERCS

ZFP2

41

Q6ZN57
TARTGEDVEMACSFR

VSTM2L

51

Q96N03
PGVQMDEDFCSRLRE

FLT1

1101

P17948
ECEIRDRDGGMRSDP

PSG5

216

Q15238
DCTFDHMGRGREEAI

ZFAND3

191

Q9H8U3
QMLLEGRAGDCARSS

JPH3

516

Q8WXH2