Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBN1 FBN2 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4	2.81e-08	188	52	8	GO:0005201
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF18 ZNF547 ZNF143 NR1I2 ZNF497 ZNF48 NR2E1 ZNF76 ZNF30 HNF4A HNF4G ZBTB1 ZIM3 NOTCH1 ZNF345 ZNF697	7.71e-08	1271	52	16	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	RLF ZNF18 ZNF547 ZNF143 NR1I2 ZNF48 NR2E1 ZNF76 ZNF30 HNF4A HNF4G ZBTB1 ZIM3 NOTCH1 ZNF345 ZNF697	3.25e-07	1412	52	16	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF18 ZNF547 ZNF143 NR1I2 ZNF497 ZNF48 NR2E1 ZNF76 ZNF30 HNF4A HNF4G ZBTB1 ZIM3 ZNF345 ZNF697	3.82e-07	1244	52	15	GO:0000978
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	RLF ZNF143 NR1I2 ZNF48 NR2E1 ZNF76 HNF4A HNF4G NOTCH1 ZNF345	1.52e-06	560	52	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	RLF ZNF143 NR1I2 ZNF48 NR2E1 ZNF76 HNF4A HNF4G NOTCH1 ZNF345	1.68e-06	566	52	10	GO:0001216
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF18 ZNF547 ZNF143 NR1I2 ZNF497 ZNF48 NR2E1 ZNF76 ZNF30 HNF4A HNF4G ZBTB1 ZIM3 ZNF345 ZNF697	2.85e-06	1459	52	15	GO:0000977
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBN1 FBN2 LAMC1	3.60e-06	12	52	3	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBN1 FBN2 LAMC1	5.94e-06	14	52	3	GO:0097493
GeneOntologyMolecularFunction	nuclear receptor activity	NR1I2 NR2E1 HNF4A HNF4G	1.79e-05	60	52	4	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR1I2 NR2E1 HNF4A HNF4G	1.91e-05	61	52	4	GO:0098531
GeneOntologyMolecularFunction	pre-mRNA 3'-splice site binding	ZRSR2P1 ZRSR2	1.39e-04	7	52	2	GO:0030628
GeneOntologyMolecularFunction	structural molecule activity	FBN1 FBN2 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4 ACTR2	4.40e-04	891	52	9	GO:0005198
GeneOntologyMolecularFunction	glycosphingolipid binding	LAMB1 LAMC1	5.09e-04	13	52	2	GO:0043208
GeneOntologyMolecularFunction	integrin binding	ITGBL1 FBN1 LAMB1 LTBP4	1.11e-03	175	52	4	GO:0005178
GeneOntologyMolecularFunction	calcium ion binding	STAB2 FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	3.13e-03	749	52	7	GO:0005509
GeneOntologyMolecularFunction	sphingolipid binding	LAMB1 LAMC1	3.54e-03	34	52	2	GO:0046625
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 FBN2	3.87e-05	4	53	2	GO:0035583
GeneOntologyBiologicalProcess	hair cell differentiation	KCNMA1 LAMC1 TECTA NOTCH1	4.81e-05	78	53	4	GO:0035315
GeneOntologyBiologicalProcess	regulation of transcription by RNA polymerase III	ZNF143 ZNF76 ZNF345	7.54e-05	32	53	3	GO:0006359
GeneOntologyCellularComponent	microfibril	FBN1 FBN2 LTBP4	4.58e-06	13	54	3	GO:0001527
GeneOntologyCellularComponent	laminin-10 complex	LAMB1 LAMC1	1.96e-05	3	54	2	GO:0043259
GeneOntologyCellularComponent	laminin-1 complex	LAMB1 LAMC1	1.96e-05	3	54	2	GO:0005606
GeneOntologyCellularComponent	extracellular matrix	FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4	4.20e-05	656	54	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4	4.30e-05	658	54	9	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 LTBP4 MUC4	6.04e-05	530	54	8	GO:0062023
GeneOntologyCellularComponent	U2AF complex	ZRSR2P1 ZRSR2	1.36e-04	7	54	2	GO:0089701
GeneOntologyCellularComponent	laminin complex	LAMB1 LAMC1	2.91e-04	10	54	2	GO:0043256
GeneOntologyCellularComponent	MLL3/4 complex	KMT2C RBBP5	4.25e-04	12	54	2	GO:0044666
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGBL1 LAMB1 LAMC1	4.78e-04	59	54	3	GO:0098636
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMB1 LAMC1	8.69e-04	17	54	2	GO:0098637
GeneOntologyCellularComponent	U12-type spliceosomal complex	ZRSR2P1 ZRSR2	2.72e-03	30	54	2	GO:0005689
GeneOntologyCellularComponent	basement membrane	FBN1 LAMB1 LAMC1	3.87e-03	122	54	3	GO:0005604
HumanPheno	Abnormal upper to lower segment ratio	FBN1 FBN2	2.42e-05	3	15	2	HP:0012772
HumanPheno	Microspherophakia	FBN1 LTBP2	4.84e-05	4	15	2	HP:0030961
HumanPheno	Iridodonesis	FBN1 LTBP2	8.05e-05	5	15	2	HP:0100693
HumanPheno	Spherophakia	FBN1 LTBP2	8.05e-05	5	15	2	HP:0034375
HumanPheno	Crumpled ear	FBN1 FBN2	1.21e-04	6	15	2	HP:0009901
HumanPheno	Lens dislocation	FBN1 FBN2 LTBP2	2.38e-04	43	15	3	HP:0000665
HumanPheno	Ectopia lentis	FBN1 FBN2 LTBP2	2.38e-04	43	15	3	HP:0001083
Domain	EGF	ITGBL1 STAB2 FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4 NOTCH1	2.01e-12	235	53	12	SM00181
Domain	EGF-like_dom	ITGBL1 STAB2 FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4 NOTCH1	3.98e-12	249	53	12	IPR000742
Domain	EGF_1	ITGBL1 STAB2 FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 LTBP4 MUC4 NOTCH1	1.14e-10	255	53	11	PS00022
Domain	EGF_2	ITGBL1 STAB2 FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 LTBP4 MUC4 NOTCH1	1.72e-10	265	53	11	PS01186
Domain	Growth_fac_rcpt_	STAB2 FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 LTBP4 NOTCH1	5.08e-10	156	53	9	IPR009030
Domain	TB	FBN1 FBN2 LTBP2 LTBP4	2.01e-09	7	53	4	PF00683
Domain	EGF-like_CS	STAB2 FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 LTBP4 MUC4 NOTCH1	2.75e-09	261	53	10	IPR013032
Domain	-	FBN1 FBN2 LTBP2 LTBP4	4.01e-09	8	53	4	3.90.290.10
Domain	TB	FBN1 FBN2 LTBP2 LTBP4	7.20e-09	9	53	4	PS51364
Domain	TB_dom	FBN1 FBN2 LTBP2 LTBP4	7.20e-09	9	53	4	IPR017878
Domain	EGF_CA	STAB2 FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	5.13e-08	122	53	7	SM00179
Domain	EGF-like_Ca-bd_dom	STAB2 FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	5.74e-08	124	53	7	IPR001881
Domain	EGF_CA	FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	1.54e-07	86	53	6	PF07645
Domain	EGF_3	STAB2 FBN1 FBN2 MEGF6 LTBP2 LTBP4 MUC4 NOTCH1	3.03e-07	235	53	8	PS50026
Domain	EGF_Ca-bd_CS	FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	3.16e-07	97	53	6	IPR018097
Domain	-	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	3.29e-07	679	53	12	3.30.160.60
Domain	EGF_CA	FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	3.57e-07	99	53	6	PS01187
Domain	ASX_HYDROXYL	FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	3.79e-07	100	53	6	PS00010
Domain	zf-C2H2	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	4.09e-07	693	53	12	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	4.15e-07	694	53	12	IPR013087
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN1 FBN2 MEGF6 LTBP2 LTBP4 NOTCH1	5.36e-07	106	53	6	IPR000152
Domain	EGF_extracell	ITGBL1 STAB2 MEGF6 LTBP2 NOTCH1	7.36e-07	60	53	5	IPR013111
Domain	EGF_2	ITGBL1 STAB2 MEGF6 LTBP2 NOTCH1	7.36e-07	60	53	5	PF07974
Domain	ZINC_FINGER_C2H2_2	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	1.33e-06	775	53	12	PS50157
Domain	ZINC_FINGER_C2H2_1	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	1.37e-06	777	53	12	PS00028
Domain	EGF	STAB2 MEGF6 LTBP2 TECTA MUC4 NOTCH1	1.48e-06	126	53	6	PF00008
Domain	Znf_C2H2-like	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	1.76e-06	796	53	12	IPR015880
Domain	Znf_C2H2	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	1.98e-06	805	53	12	IPR007087
Domain	ZnF_C2H2	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	2.06e-06	808	53	12	SM00355
Domain	Retinoid-X_rcpt/HNF4	NR2E1 HNF4A HNF4G	2.55e-06	10	53	3	IPR000003
Domain	EGF_Lam	STAB2 MEGF6 LAMB1 LAMC1	2.83e-06	35	53	4	SM00180
Domain	Laminin_EGF	STAB2 MEGF6 LAMB1 LAMC1	3.97e-06	38	53	4	IPR002049
Domain	zf-C4	NR1I2 NR2E1 HNF4A HNF4G	8.63e-06	46	53	4	PF00105
Domain	NUCLEAR_REC_DBD_1	NR1I2 NR2E1 HNF4A HNF4G	8.63e-06	46	53	4	PS00031
Domain	Znf_hrmn_rcpt	NR1I2 NR2E1 HNF4A HNF4G	8.63e-06	46	53	4	IPR001628
Domain	Nuclear_hrmn_rcpt	NR1I2 NR2E1 HNF4A HNF4G	8.63e-06	46	53	4	IPR001723
Domain	ZnF_C4	NR1I2 NR2E1 HNF4A HNF4G	8.63e-06	46	53	4	SM00399
Domain	NUCLEAR_REC_DBD_2	NR1I2 NR2E1 HNF4A HNF4G	8.63e-06	46	53	4	PS51030
Domain	-	NR1I2 NR2E1 HNF4A HNF4G	9.42e-06	47	53	4	1.10.565.10
Domain	HOLI	NR1I2 NR2E1 HNF4A HNF4G	1.02e-05	48	53	4	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	NR1I2 NR2E1 HNF4A HNF4G	1.02e-05	48	53	4	IPR000536
Domain	Hormone_recep	NR1I2 NR2E1 HNF4A HNF4G	1.02e-05	48	53	4	PF00104
Domain	-	NR1I2 NR2E1 HNF4A HNF4G	2.04e-05	57	53	4	3.30.50.10
Domain	Znf_NHR/GATA	NR1I2 NR2E1 HNF4A HNF4G	2.19e-05	58	53	4	IPR013088
Domain	FBN	FBN1 FBN2	2.37e-05	3	53	2	IPR011398
Domain	hEGF	FBN2 MEGF6 NOTCH1	6.72e-05	28	53	3	PF12661
Domain	NIDO_dom	TECTA MUC4	7.86e-05	5	53	2	IPR003886
Domain	NIDO	TECTA MUC4	7.86e-05	5	53	2	PS51220
Domain	COUP_TF	HNF4A HNF4G	7.86e-05	5	53	2	IPR003068
Domain	NIDO	TECTA MUC4	7.86e-05	5	53	2	SM00539
Domain	U2AF_small	ZRSR2P1 ZRSR2	7.86e-05	5	53	2	IPR009145
Domain	NIDO	TECTA MUC4	7.86e-05	5	53	2	PF06119
Domain	EGF_LAM_2	STAB2 LAMB1 LAMC1	8.30e-05	30	53	3	PS50027
Domain	EGF_LAM_1	STAB2 LAMB1 LAMC1	8.30e-05	30	53	3	PS01248
Domain	Laminin_EGF	MEGF6 LAMB1 LAMC1	1.32e-04	35	53	3	PF00053
Domain	ZnF_C3H1	ZRSR2P1 RNF113B ZRSR2	3.41e-04	48	53	3	SM00356
Domain	Chromo_dom_subgr	CDY2A CDY1	3.50e-04	10	53	2	IPR017984
Domain	zf-CCCH	ZRSR2P1 RNF113B ZRSR2	3.62e-04	49	53	3	PF00642
Domain	Znf_CCCH	ZRSR2P1 RNF113B ZRSR2	5.96e-04	58	53	3	IPR000571
Domain	LAMININ_NTER	LAMB1 LAMC1	9.24e-04	16	53	2	PS51117
Domain	VWFD	TECTA MUC4	9.24e-04	16	53	2	PS51233
Domain	Laminin_N	LAMB1 LAMC1	9.24e-04	16	53	2	PF00055
Domain	VWD	TECTA MUC4	9.24e-04	16	53	2	SM00216
Domain	VWF_type-D	TECTA MUC4	9.24e-04	16	53	2	IPR001846
Domain	Laminin_N	LAMB1 LAMC1	9.24e-04	16	53	2	IPR008211
Domain	VWD	TECTA MUC4	9.24e-04	16	53	2	PF00094
Domain	LamNT	LAMB1 LAMC1	9.24e-04	16	53	2	SM00136
Domain	Crotonase_core_superfam	CDY2A CDY1	1.05e-03	17	53	2	IPR001753
Domain	ECH_1	CDY2A CDY1	1.05e-03	17	53	2	PF00378
Domain	zf-C2H2_6	ZNF497 ZNF48 ZNF30 ZIM3 ZNF345	1.93e-03	314	53	5	PF13912
Domain	cEGF	FBN1 FBN2	2.46e-03	26	53	2	IPR026823
Domain	Chromo	CDY2A CDY1	2.46e-03	26	53	2	PF00385
Domain	cEGF	FBN1 FBN2	2.46e-03	26	53	2	PF12662
Domain	CHROMO_2	CDY2A CDY1	2.85e-03	28	53	2	PS50013
Domain	CHROMO_1	CDY2A CDY1	2.85e-03	28	53	2	PS00598
Domain	Chromodomain-like	CDY2A CDY1	3.71e-03	32	53	2	IPR016197
Domain	CHROMO	CDY2A CDY1	3.94e-03	33	53	2	SM00298
Domain	Chromo/shadow_dom	CDY2A CDY1	3.94e-03	33	53	2	IPR000953
Domain	-	RNF113B ZRSR2	5.75e-03	40	53	2	4.10.1000.10
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FBN2 LTBP2 LTBP4	2.30e-06	32	42	4	MM14854
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FBN2 LTBP2 LTBP4	4.19e-06	37	42	4	M27134
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 FBN2 LTBP2 LTBP4	5.19e-06	39	42	4	MM14601
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 FBN2 LTBP2 LTBP4	8.47e-06	44	42	4	M26969
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR1I2 NR2E1 HNF4A HNF4G	1.79e-05	53	42	4	M8276
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	FBN1 FBN2 CAPN7 LAMB1 LAMC1 LTBP2 LTBP4	2.62e-05	300	42	7	M610
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	KMT2C ZNF18 ITGBL1 ZNF547 ZNF143 NR1I2 RBBP5 NR2E1 ZNF30 HNF4A HNF4G ZIM3 NOTCH1 ZNF697	2.79e-05	1387	42	14	M734
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FBN1 FBN2 LTBP2	5.40e-05	25	42	3	M39713
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	FBN1 FBN2 CAPN7 LAMB1 LAMC1	5.69e-05	140	42	5	M587
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	FBN1 FBN2 MEGF6 CAPN7 LTBP2 LTBP4	1.07e-04	258	42	6	MM14572
Pathway	WP_NUCLEAR_RECEPTORS	NR1I2 NR2E1 HNF4A	1.93e-04	38	42	3	M39657
Pathway	WP_NUCLEAR_RECEPTORS	NR1I2 NR2E1 HNF4A	1.93e-04	38	42	3	MM15865
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	FBN1 LTBP2 LTBP4	1.93e-04	38	42	3	MM14874
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP4	2.40e-04	8	42	2	M47850
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	HNF4A HNF4G NOTCH1	2.60e-04	42	42	3	M17541
Pathway	PID_INTEGRIN3_PATHWAY	FBN1 LAMB1 LAMC1	2.79e-04	43	42	3	M53
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	FBN1 LTBP2 LTBP4	3.64e-04	47	42	3	M646
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR1I2 NR2E1 HNF4A	3.87e-04	48	42	3	MM14987
Pathway	PID_INTEGRIN4_PATHWAY	LAMB1 LAMC1	4.69e-04	11	42	2	M158
Pathway	BIOCARTA_PRION_PATHWAY	LAMB1 LAMC1	5.61e-04	12	42	2	M22020
Pathway	PID_INTEGRIN1_PATHWAY	FBN1 LAMB1 LAMC1	9.88e-04	66	42	3	M18
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	FBN1 LTBP2 LTBP4	1.54e-03	77	42	3	MM14670
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	HNF4A HNF4G	1.76e-03	21	42	2	M14966
Pathway	KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG	HNF4A HNF4G	2.49e-03	25	42	2	M18312
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	FBN1 LTBP2 LTBP4	2.73e-03	94	42	3	M1041
Pathway	WP_KLEEFSTRA_SYNDROME	KMT2C RBBP5	3.34e-03	29	42	2	M48076
Pathway	REACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION	LAMB1 LAMC1	3.34e-03	29	42	2	M29808
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMB1 LAMC1	3.58e-03	30	42	2	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMB1 LAMC1	3.58e-03	30	42	2	M27216
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	LAMB1 LAMC1	3.58e-03	30	42	2	M39641
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	LAMB1 LAMC1	3.58e-03	30	42	2	MM15812
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 LTBP4 MUC4	2.99e-10	175	54	8	28071719
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 FBN2 LTBP4	1.41e-08	4	54	3	12429738
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	FBN1 FBN2 LAMB1 LAMC1	1.56e-08	18	54	4	39040056
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	FBN1 FBN2 LAMB1 LAMC1	7.56e-08	26	54	4	34189436
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 FBN2 MEGF6	2.95e-07	9	54	3	12122015
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	FBN1 FBN2 LAMB1 LAMC1	3.30e-07	37	54	4	34323105
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	FBN1 LAMB1 LAMC1 LTBP2 LTBP4	4.32e-07	97	54	5	27559042
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	FBN1 FBN2 LAMB1 LAMC1	1.13e-06	50	54	4	23658023
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	FBN1 MEGF6 LAMB1 LTBP4 NOTCH1	1.14e-06	118	54	5	21078624
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	NR1I2 LAMB1 LAMC1 HNF4A HNF4G	2.06e-06	133	54	5	15604093
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	FBN1 FBN2 LAMB1 LAMC1 LTBP4	2.22e-06	135	54	5	28675934
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SLC25A3 ITGBL1 FBN1 MEGF6 LAMC1 FRYL LTBP4 NOTCH1	2.33e-06	560	54	8	21653829
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	2.37e-06	2	54	2	12399449
Pubmed	Latent TGF-β binding protein 2 and 4 have essential overlapping functions in microfibril development.	LTBP2 LTBP4	2.37e-06	2	54	2	28252045
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	2.37e-06	2	54	2	21851253
Pubmed	Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4.	HNF4A HNF4G	2.37e-06	2	54	2	33503426
Pubmed	Intestine-specific ablation of the Hepatocyte Nuclear Factor 4a (Hnf4a) gene in mice has minimal impact on serum lipids and ileum gene expression profile due to upregulation of its paralog Hnf4g.	HNF4A HNF4G	2.37e-06	2	54	2	34973414
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	2.37e-06	2	54	2	12429739
Pubmed	Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.	HNF4A HNF4G	2.37e-06	2	54	2	21047794
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	2.37e-06	2	54	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	2.37e-06	2	54	2	21440062
Pubmed	Pregnane X receptor and hepatocyte nuclear factor 4α polymorphisms are cooperatively associated with carbamazepine autoinduction.	NR1I2 HNF4A	2.37e-06	2	54	2	24384557
Pubmed	cDNA cloning, expression and mapping of human laminin B2 gene to chromosome 1q31.	LAMB1 LAMC1	2.37e-06	2	54	2	3402995
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	2.37e-06	2	54	2	15131124
Pubmed	Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking.	LAMB1 LAMC1	2.37e-06	2	54	2	20939100
Pubmed	ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf.	ZNF143 ZNF76	2.37e-06	2	54	2	9705341
Pubmed	Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids.	HNF4A HNF4G	2.37e-06	2	54	2	12220494
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	2.37e-06	2	54	2	12524050
Pubmed	ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells.	ZRSR2P1 ZRSR2	2.37e-06	2	54	2	33691379
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	2.37e-06	2	54	2	20404337
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	2.37e-06	2	54	2	8791520
Pubmed	A novel disulfide pattern in laminin-type epidermal growth factor-like (LE) modules of laminin β1 and γ1 chains.	LAMB1 LAMC1	2.37e-06	2	54	2	20731416
Pubmed	Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes.	HNF4A HNF4G	2.37e-06	2	54	2	8622695
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	2.37e-06	2	54	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	2.37e-06	2	54	2	35419902
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	2.37e-06	2	54	2	8307578
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	2.37e-06	2	54	2	10504303
Pubmed	Involvement of hepatocyte nuclear factor 4 alpha in transcriptional regulation of the human pregnane X receptor gene in the human liver.	NR1I2 HNF4A	2.37e-06	2	54	2	18305375
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	2.37e-06	2	54	2	7744963
Pubmed	Transcriptional regulation of the mouse cytosolic chaperonin subunit gene Ccta/t-complex polypeptide 1 by selenocysteine tRNA gene transcription activating factor family zinc finger proteins.	ZNF143 ZNF76	2.37e-06	2	54	2	10893243
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	2.37e-06	2	54	2	26408953
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	2.37e-06	2	54	2	18006876
Pubmed	Suppression of the pregnane X receptor during endoplasmic reticulum stress is achieved by down-regulating hepatocyte nuclear factor-4α and up-regulating liver-enriched inhibitory protein.	NR1I2 HNF4A	2.37e-06	2	54	2	25616597
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	2.37e-06	2	54	2	24833718
Pubmed	Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development.	ZRSR2P1 ZRSR2	2.37e-06	2	54	2	35198906
Pubmed	Epigenetic control of HNF-4α in colon carcinoma cells affects MUC4 expression and malignancy.	HNF4A MUC4	2.37e-06	2	54	2	23307400
Pubmed	Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development.	NR1I2 HNF4A	2.37e-06	2	54	2	12774017
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	2.37e-06	2	54	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	2.37e-06	2	54	2	20529844
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	2.37e-06	2	54	2	25524144
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	2.37e-06	2	54	2	23133647
Pubmed	Molecular Characterization of the Lipid Genome-Wide Association Study Signal on Chromosome 18q11.2 Implicates HNF4A-Mediated Regulation of the TMEM241 Gene.	TMEM241 HNF4A	2.37e-06	2	54	2	27199446
Pubmed	Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.	FBN1 LTBP2	2.37e-06	2	54	2	24867584
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	2.37e-06	2	54	2	16407178
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	2.37e-06	2	54	2	1852206
Pubmed	Induction of Hepatic Metabolic Functions by a Novel Variant of Hepatocyte Nuclear Factor 4γ.	HNF4A HNF4G	2.37e-06	2	54	2	30224520
Pubmed	Glucose Tolerance Is Improved in Mice Invalidated for the Nuclear Receptor HNF-4γ: A Critical Role for Enteroendocrine Cell Lineage.	HNF4A HNF4G	2.37e-06	2	54	2	25829452
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	2.37e-06	2	54	2	10359653
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	2.40e-06	248	54	6	24006456
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	FBN1 LAMB1 LAMC1 LTBP2 LTBP4	3.26e-06	146	54	5	27068509
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FBN1 LAMB1 LAMC1 LTBP2 LTBP4	6.29e-06	167	54	5	22159717
Pubmed	Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.	LAMB1 LAMC1	7.09e-06	3	54	2	2100263
Pubmed	A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity.	HNF4A HNF4G	7.09e-06	3	54	2	30988513
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	7.09e-06	3	54	2	10825173
Pubmed	Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1.	ZRSR2P1 ZRSR2	7.09e-06	3	54	2	8586425
Pubmed	Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.	LAMB1 LAMC1	7.09e-06	3	54	2	7669546
Pubmed	The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac.	HNF4A HNF4G	7.09e-06	3	54	2	34001900
Pubmed	Three-dimensional analysis of the developing pituitary gland in the mouse.	LAMB1 LAMC1	7.09e-06	3	54	2	9603432
Pubmed	Importance of nidogen binding to laminin gamma1 for branching epithelial morphogenesis of the submandibular gland.	LAMB1 LAMC1	7.09e-06	3	54	2	9043083
Pubmed	Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice.	ZRSR2P1 ZRSR2	7.09e-06	3	54	2	36030305
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	7.09e-06	3	54	2	30201140
Pubmed	Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.	NR1I2 HNF4A	7.09e-06	3	54	2	15322103
Pubmed	Differential expression of laminin A and B chains during development of embryonic mouse organs.	LAMB1 LAMC1	7.09e-06	3	54	2	2088723
Pubmed	PXR, CAR and HNF4alpha genotypes and their association with pharmacokinetics and pharmacodynamics of docetaxel and doxorubicin in Asian patients.	NR1I2 HNF4A	7.09e-06	3	54	2	17876342
Pubmed	Pregnane X Receptor Represses HNF4α Gene to Induce Insulin-Like Growth Factor-Binding Protein IGFBP1 that Alters Morphology of and Migrates HepG2 Cells.	NR1I2 HNF4A	7.09e-06	3	54	2	26232425
Pubmed	Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.	LAMB1 LAMC1	7.09e-06	3	54	2	1907584
Pubmed	Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.	LAMB1 LAMC1	7.09e-06	3	54	2	1292752
Pubmed	Monocytic cells synthesize, adhere to, and migrate on laminin-8 (alpha 4 beta 1 gamma 1).	LAMB1 LAMC1	7.09e-06	3	54	2	11067943
Pubmed	Downregulation of a newly identified laminin, laminin-3B11, in vascular basement membranes of invasive human breast cancers.	LAMB1 LAMC1	7.09e-06	3	54	2	21276136
Pubmed	Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.	LAMB1 LAMC1	7.09e-06	3	54	2	6209134
Pubmed	LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.	FBN1 LTBP2	7.09e-06	3	54	2	17293099
Pubmed	The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha.	NR1I2 HNF4A	7.09e-06	3	54	2	17764444
Pubmed	An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients.	LAMB1 LAMC1	7.09e-06	3	54	2	12615822
Pubmed	Lack of association of single-nucleotide polymorphisms in pregnane X receptor, hepatic nuclear factor 4alpha, and constitutive androstane receptor with docetaxel pharmacokinetics.	NR1I2 HNF4A	7.09e-06	3	54	2	18056193
Pubmed	Determinants of laminin polymerization revealed by the structure of the α5 chain amino-terminal region.	LAMB1 LAMC1	7.09e-06	3	54	2	21311558
Pubmed	HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort.	LAMB1 HNF4A	7.09e-06	3	54	2	21744425
Pubmed	Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.	FBN1 FBN2	7.09e-06	3	54	2	20855508
Pubmed	Heritable Thoracic Aortic Disease Overview	FBN1 FBN2 NOTCH1	1.39e-05	30	54	3	20301299
Pubmed	Hepatocyte nuclear factor-4 alpha/gamma and hepatocyte nuclear factor-1 alpha as causal factors of interindividual difference in the expression of human dihydrodiol dehydrogenase 4 mRNA in human livers.	HNF4A HNF4G	1.42e-05	4	54	2	12544512
Pubmed	The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.	NR1I2 HNF4A	1.42e-05	4	54	2	15919766
Pubmed	Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.	LAMB1 LAMC1	1.42e-05	4	54	2	12820173
Pubmed	Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.	NR1I2 HNF4A	1.42e-05	4	54	2	22333269
Pubmed	Human eye development is characterized by coordinated expression of fibrillin isoforms.	FBN1 FBN2	1.42e-05	4	54	2	25406291
Pubmed	Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.	FBN1 LTBP2	1.42e-05	4	54	2	21540769
Pubmed	Mouse U2af1-rs1 is a neomorphic imprinted gene.	ZRSR2P1 ZRSR2	1.42e-05	4	54	2	9001233
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP2 LTBP4	1.42e-05	4	54	2	15611103
Pubmed	Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146).	LAMB1 LAMC1	1.42e-05	4	54	2	24951930
Pubmed	Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.	FBN1 FBN2	1.42e-05	4	54	2	20729550
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN2	1.42e-05	4	54	2	25034023
Pubmed	Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.	LAMB1 LAMC1	1.42e-05	4	54	2	9299121
Interaction	NTN5 interactions	FBN1 FBN2 LTBP4 NOTCH1	4.70e-07	24	54	4	int:NTN5
Interaction	ATN1 interactions	KMT2C MEGF6 RBBP5 KRTAP19-2 NR2E1 LTBP4	1.05e-05	187	54	6	int:ATN1
Interaction	ATXN7 interactions	FBN1 MEGF6 LAMB1 HNF4A LTBP4	1.08e-05	109	54	5	int:ATXN7
Interaction	MFAP5 interactions	FBN1 FBN2 MEGF6 LTBP4	1.13e-05	52	54	4	int:MFAP5
Interaction	MBD1 interactions	SLC25A3 MEGF6 LTBP4 NOTCH1	5.39e-05	77	54	4	int:MBD1
Interaction	LTBP2 interactions	FBN2 ZNF497 LTBP2 LTBP4	7.94e-05	85	54	4	int:LTBP2
Interaction	ZNF74 interactions	LTBP2 LTBP4 NOTCH1	1.03e-04	34	54	3	int:ZNF74
Cytoband	8q21.11	HNF4G CRISPLD1	5.03e-04	28	54	2	8q21.11
Cytoband	21q22.1	KRTAP13-4 KRTAP19-2	9.79e-04	39	54	2	21q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF547 ZNF497 ZNF30 LTBP4 ZIM3 ZNF345	2.70e-03	1192	54	6	chr19q13
Cytoband	19q13.43	ZNF547 ZNF497	4.77e-03	87	54	2	19q13.43
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF18 ZNF547 ZNF143 ZNF497 ZNF48 ZNF76 ZNF30 ZBTB1 ZIM3 ZNF345 ZNF697	6.94e-08	718	43	12	28
GeneFamily	Nuclear hormone receptors	NR1I2 NR2E1 HNF4A HNF4G	5.44e-06	49	43	4	71
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP2 LTBP4	3.31e-05	4	43	2	628
GeneFamily	Laminin subunits	LAMB1 LAMC1	3.59e-04	12	43	2	626
GeneFamily	Zinc fingers CCCH-type	ZRSR2P1 ZRSR2	3.13e-03	35	43	2	73
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN1 FBN2 LAMB1 LAMC1 LTBP2 TECTA LTBP4 CRISPLD1	4.60e-09	191	53	8	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN1 FBN2 LAMB1 LAMC1 LTBP2 TECTA LTBP4 CRISPLD1	5.63e-09	196	53	8	M3008
Coexpression	NABA_CORE_MATRISOME	FBN1 FBN2 LAMB1 LAMC1 LTBP2 TECTA LTBP4 CRISPLD1	6.78e-08	270	53	8	MM17057
Coexpression	NABA_CORE_MATRISOME	FBN1 FBN2 LAMB1 LAMC1 LTBP2 TECTA LTBP4 CRISPLD1	7.81e-08	275	53	8	M5884
Coexpression	NABA_MATRISOME	FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4 CRISPLD1	2.93e-05	1008	53	10	MM17056
Coexpression	NABA_MATRISOME	FBN1 FBN2 MEGF6 LAMB1 LAMC1 LTBP2 TECTA LTBP4 MUC4 CRISPLD1	3.41e-05	1026	53	10	M5889
Coexpression	LIM_MAMMARY_STEM_CELL_UP	KCNMA1 LAMB1 LHFPL6 LAMC1 ARHGEF25 LTBP4 CRISPLD1	4.86e-05	479	53	7	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	KCNMA1 LAMB1 LHFPL6 LAMC1 ARHGEF25 LTBP4 CRISPLD1	5.12e-05	483	53	7	MM1082
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN	FBN1 ZRSR2 LTBP2 HNF4A NOTCH1	5.24e-05	200	53	5	M9657
Coexpression	SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	ITGBL1 FBN1 FBN2 LAMB1 LHFPL6 LAMC1	7.58e-05	352	53	6	M17471
Coexpression	CUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL	FBN1 LAMB1 LAMC1 LTBP4	9.33e-05	117	53	4	M39300
Coexpression	HAY_BONE_MARROW_STROMAL	ITGBL1 FBN1 KRTAP13-4 LHFPL6 LAMC1 LTBP2 ARHGEF25 CRISPLD1	1.43e-04	767	53	8	M39209
Coexpression	BROWNE_HCMV_INFECTION_24HR_DN	FBN1 FBN2 KCNMA1 LAMC1	2.13e-04	145	53	4	M14098
Coexpression	MARTINEZ_TP53_TARGETS_DN	FBN2 KRTAP13-4 FRYL LTBP2 ARHGEF25 HNF4G NOTCH1	2.29e-04	615	53	7	M8673
CoexpressionAtlas	Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4	STAB2 FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	7.13e-05	439	50	7	GSM777059_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	FBN1 LAMB1 LAMC1 LTBP4	8.02e-05	97	50	4	GSM777043_100
CoexpressionAtlas	Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4	STAB2 FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	8.33e-05	450	50	7	GSM777063_500
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	3.84e-09	195	54	7	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 ARHGEF25 LTBP4	4.42e-09	199	54	7	e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	4.42e-09	199	54	7	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ITGBL1 FBN1 KCNMA1 LHFPL6 LAMC1 ARHGEF25 LTBP4	4.42e-09	199	54	7	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 LAMB1 LHFPL6 LTBP2 ARHGEF25 LTBP4 CRISPLD1	4.42e-09	199	54	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ITGBL1 FBN1 KCNMA1 LHFPL6 LAMC1 ARHGEF25 LTBP4	4.58e-09	200	54	7	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 FBN2 LAMB1 LHFPL6 LTBP4	1.04e-07	187	54	6	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 FBN2 LAMB1 LHFPL6 LTBP4	1.04e-07	187	54	6	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 FBN2 LAMB1 LHFPL6 LTBP4	1.04e-07	187	54	6	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	1.07e-07	188	54	6	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	1.18e-07	191	54	6	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LHFPL6 LAMC1 ARHGEF25 LTBP4	1.22e-07	192	54	6	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.22e-07	192	54	6	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LAMB1 LHFPL6 LAMC1 ARHGEF25 LTBP4	1.29e-07	194	54	6	d47e3c7b22444aef0c7a37bc8cd8853b590a56dd
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	1.29e-07	194	54	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.33e-07	195	54	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	18-Distal-Mesenchymal-Mesenchyme_SERPINF1-high\|Distal / Age, Tissue, Lineage and Cell class	ITGBL1 FBN1 FBN2 LHFPL6 LTBP2 LTBP4	1.33e-07	195	54	6	f86737bff21d81673238813df61a15cfe88d0b15
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.33e-07	195	54	6	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.33e-07	195	54	6	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	ITGBL1 FBN1 LHFPL6 LAMC1 LTBP2 LTBP4	1.33e-07	195	54	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.33e-07	195	54	6	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.37e-07	196	54	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.37e-07	196	54	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	PND14-Mesenchymal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 LAMB1 LHFPL6 LTBP2 ARHGEF25 LTBP4	1.42e-07	197	54	6	9a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	ITGBL1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	1.42e-07	197	54	6	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	PND03-Mesenchymal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 LAMB1 LHFPL6 LTBP2 ARHGEF25 LTBP4	1.42e-07	197	54	6	e3053ef8f604b6892c21c03e12612b49d3d30f23
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 LAMB1 LHFPL6 LAMC1 LTBP4 MUC4	1.42e-07	197	54	6	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 FBN2 LAMB1 LHFPL6 LTBP2 ARHGEF25	1.46e-07	198	54	6	a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.46e-07	198	54	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	3'-Broncho-tracheal-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LHFPL6 LTBP2 ARHGEF25 LTBP4	1.46e-07	198	54	6	4961a3e9b953679648586afed04869ff36b81820
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.46e-07	198	54	6	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	5'-Parenchyma_lung-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.46e-07	198	54	6	aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 FBN2 LAMB1 LHFPL6 LAMC1 LTBP4	1.50e-07	199	54	6	84545ced0c792bc77980a50d65e484eab648d47e
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ITGBL1 FBN1 LAMB1 LHFPL6 LAMC1 CRISPLD1	1.50e-07	199	54	6	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.50e-07	199	54	6	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FBN1 LHFPL6 LTBP2 ARHGEF25 LTBP4 CRISPLD1	1.50e-07	199	54	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	ASK452-Mesenchymal-Fibroblast\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.50e-07	199	54	6	4d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 FBN2 LAMB1 LHFPL6 LAMC1 LTBP4	1.50e-07	199	54	6	e78f661b40da34768469549b6e755d330be6bbd8
ToppCell	ASK452-Mesenchymal\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.50e-07	199	54	6	93e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCell	Parenchymal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	cellseq-Mesenchymal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.55e-07	200	54	6	238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITGBL1 FBN1 KCNMA1 LHFPL6 ARHGEF25 LTBP4	1.55e-07	200	54	6	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 KCNMA1 LHFPL6 ARHGEF25 LTBP4 CRISPLD1	1.55e-07	200	54	6	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Bronchial-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	5ea12e17f50fefbf5534e487af3392b2fa2d13ad
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	6316c288022719b9e6c4332c5cb9041e1188d0e8
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	FBN1 KCNMA1 LHFPL6 ARHGEF25 LTBP4 CRISPLD1	1.55e-07	200	54	6	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	3'-Parenchyma_lung-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2 LTBP4	1.55e-07	200	54	6	ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGBL1 FBN1 LHFPL6 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FBN1 KCNMA1 LHFPL6 ARHGEF25 LTBP4 CRISPLD1	1.55e-07	200	54	6	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 LAMB1 LHFPL6 LTBP2 LTBP4 CRISPLD1	1.55e-07	200	54	6	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGBL1 FBN1 LHFPL6 LAMC1 LTBP2 LTBP4	1.55e-07	200	54	6	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 SLC12A1 ABCA12 KCNMA1 TECTA	1.47e-06	160	54	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 SLC12A1 ABCA12 KCNMA1 TECTA	1.47e-06	160	54	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LTBP2 LTBP4	2.28e-06	175	54	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 FBN1 LHFPL6 LTBP2 LTBP4	2.28e-06	175	54	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ITGBL1 FBN1 LAMC1 LTBP2 CRISPLD1	2.48e-06	178	54	5	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	ITGBL1 FBN1 LHFPL6 LAMC1 LTBP4	2.55e-06	179	54	5	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LTBP2 LTBP4	2.69e-06	181	54	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	ITGBL1 FBN1 FBN2 LAMB1 LTBP2	2.69e-06	181	54	5	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	2.76e-06	182	54	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2	2.76e-06	182	54	5	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 LTBP2 TECTA ARHGEF25 LTBP4	2.84e-06	183	54	5	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FBN1 FBN2 KCNMA1 LHFPL6 LTBP2	2.99e-06	185	54	5	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2	2.99e-06	185	54	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 FBN2 LHFPL6 LTBP4	2.99e-06	185	54	5	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 FBN2 LHFPL6 LTBP4	2.99e-06	185	54	5	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 FBN2 LHFPL6 LTBP4	3.07e-06	186	54	5	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LTBP2 LTBP4	3.07e-06	186	54	5	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ITGBL1 FBN1 LAMC1 LTBP2 LTBP4	3.15e-06	187	54	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 FBN1 MEGF6 LHFPL6 LTBP4	3.24e-06	188	54	5	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.32e-06	189	54	5	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 LHFPL6 LAMC1 LTBP2 LTBP4	3.32e-06	189	54	5	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.32e-06	189	54	5	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.32e-06	189	54	5	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.41e-06	190	54	5	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 FBN1 MEGF6 LHFPL6 LTBP4	3.41e-06	190	54	5	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.41e-06	190	54	5	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.49e-06	191	54	5	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FBN1 LHFPL6 LAMC1 LTBP2 LTBP4	3.49e-06	191	54	5	9bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LAMC1 ARHGEF25 LTBP4	3.49e-06	191	54	5	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 FBN1 LAMB1 LTBP2 LTBP4	3.49e-06	191	54	5	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2	3.49e-06	191	54	5	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 LHFPL6 LAMC1 LTBP2 LTBP4	3.49e-06	191	54	5	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LAMC1 ARHGEF25 LTBP4	3.49e-06	191	54	5	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2	3.49e-06	191	54	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITGBL1 FBN1 LAMB1 LHFPL6 LTBP2	3.49e-06	191	54	5	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FBN1 LAMB1 LAMC1 LTBP2	3.59e-06	192	54	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 FBN2 LAMB1 LHFPL6 LTBP4	3.59e-06	192	54	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FBN1 LAMB1 LHFPL6 LAMC1 LTBP2	3.59e-06	192	54	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.59e-06	192	54	5	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 LAMB1 LHFPL6 LAMC1	3.59e-06	192	54	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGBL1 FBN1 LAMB1 LAMC1 LTBP4	3.59e-06	192	54	5	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGBL1 FBN1 FBN2 LTBP2 LTBP4	3.59e-06	192	54	5	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	droplet-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.59e-06	192	54	5	086b47f87283cd41139cd56686011f8b5821b0da
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMB1 LHFPL6 LAMC1 LTBP4	3.59e-06	192	54	5	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 FBN1 LAMB1 LAMC1 LTBP4	3.59e-06	192	54	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
Computational	Neighborhood of CDH11	FBN1 LAMB1 LAMC1	3.50e-05	25	28	3	GNF2_CDH11
Computational	Neighborhood of PTX3	FBN1 LAMB1 LAMC1	1.07e-04	36	28	3	GNF2_PTX3
Computational	Adhesion molecules.	ITGBL1 FBN1 FBN2 LAMB1	4.55e-04	141	28	4	MODULE_122
Drug	funiferine N-oxide	FBN1 FBN2 LTBP2 LTBP4	5.53e-06	49	54	4	CID000191631
Drug	5 beta-pregnanediol	NR1I2 KCNMA1 HNF4A HNF4G	1.25e-05	60	54	4	CID000012547
Drug	ALT-711	KCNMA1 LAMB1 LAMC1	1.63e-05	21	54	3	CID000216304
Disease	Marfan Syndrome	FBN1 LAMC1 LTBP2	6.61e-07	11	48	3	C0024796
Disease	maturity-onset diabetes of the young type 1 (implicated_via_orthology)	HNF4A HNF4G	2.59e-06	2	48	2	DOID:0111099 (implicated_via_orthology)
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2	7.77e-06	3	48	2	DOID:65 (implicated_via_orthology)
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	7.77e-06	3	48	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	FBN1 LTBP2	7.77e-06	3	48	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	FBN1 LTBP2	7.77e-06	3	48	2	C1869114
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	1.55e-05	4	48	2	DOID:0060249 (is_implicated_in)
Disease	Fanconi syndrome (implicated_via_orthology)	HNF4A HNF4G	1.55e-05	4	48	2	DOID:1062 (implicated_via_orthology)
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	1.55e-05	4	48	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 LTBP2	1.55e-05	4	48	2	DOID:0050475 (is_implicated_in)
Disease	Familial thoracic aortic aneurysm and aortic dissection	FBN1 FBN2 NOTCH1	8.94e-05	53	48	3	C4707243
Disease	Marfan Syndrome, Type I	FBN1 LAMC1	9.26e-05	9	48	2	C4721845
Disease	maturity-onset diabetes of the young (implicated_via_orthology)	HNF4A HNF4G	1.16e-04	10	48	2	DOID:0050524 (implicated_via_orthology)
Disease	Spermatogenic Failure, Nonobstructive, Y-Linked	CDY2A CDY1	3.06e-04	16	48	2	C1839071
Disease	SPERMATOGENIC FAILURE, Y-LINKED, 2	CDY2A CDY1	3.06e-04	16	48	2	415000
Disease	Spermatogenic failure, Y-linked, 2	CDY2A CDY1	3.06e-04	16	48	2	cv:C1839071
Disease	aortic measurement	FBN1 HNF4G LTBP4 CRISPLD1	7.41e-04	251	48	4	EFO_0020865
Disease	brain cancer (implicated_via_orthology)	NR2E1 NOTCH1	8.21e-04	26	48	2	DOID:1319 (implicated_via_orthology)
Disease	ascending aortic diameter	FBN1 FBN2 CRISPLD1	1.55e-03	140	48	3	EFO_0021787

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAGSVFCCGLDFGYF	CDY1	336	Q9Y6F8
SAAGSVFCCGLDFGY	CDY2A	336	Q9Y6F7
AKCGCCFARGGRESY	ARHGEF25	21	Q86VW2
RCCGSPFYLKEAFGD	ABCA12	1556	Q86UK0
CDNGTGFVKCGYAGS	ACTR2	11	P61160
YGDCCLAVSADGGLF	RCC1L	291	Q96I51
EGDHSFYLSCRCGGK	DNAJC24	106	Q6P3W2
EVAGCKCDGGTFGRY	MUC4	5056	Q99102
KCDGGTFGRYCEGSE	MUC4	5061	Q99102
SCDYGSGRFFILCGL	SLC25A3	56	Q00325
SFCRLGYGCGYEGCR	KRTAP19-2	11	Q3LHN2
GVADYACSCALGFSG	NOTCH1	81	P46531
FCYCGEKSSLGQGDL	KMT2C	136	Q8NEZ4
ADLGDGGCYGDLFCK	KCNMA1	1111	Q12791
HYGASSCDGCKGFFR	HNF4A	71	P41235
RCYTGSGRVAAGCFK	FRYL	1176	O94915
IGSRCDDCASGYFGN	LAMB1	951	P07942
CGRLSYCLEDTAGGF	NR1I2	301	O75469
TCGYTSGQFDLGKCE	LHFPL6	151	Q9Y693
GKHYGASSCDGCKGF	HNF4G	21	Q14541
KCCFSGDGEYIVAGS	RBBP5	256	Q15291
TGCEFYAFCGALFGI	OPN4	141	Q9UHM6
GFLRKSSGDYRCGFC	CAPN7	756	Q9Y6W3
GDFECKCDEGYESGF	FBN1	1091	P35555
SYRCLCKEGYTGDGF	FBN1	1386	P35555
CKEGYTGDGFTCTDL	FBN1	1391	P35555
FGGGCRENLCYKEGS	CRISPLD1	231	Q9H336
TAGSFSCKDCDGGYR	LTBP2	1111	Q14767
FGYCFRELRGGECAS	LTBP4	286	Q8N2S1
CCYSLGNGSSGFRFL	KRTAP13-4	101	Q3LI77
TAGFYCDRCKDGFFG	LAMC1	856	P11047
SYRCACSEGFTGDGF	FBN2	1431	P35556
FRLCNSTGGDCFYRG	SCNN1D	371	P51172
NSDGSGLVYGKFCEC	ITGBL1	166	O95965
KHYGVYACDGCSGFF	NR2E1	26	Q9Y466
YACDGCSGFFKRSIR	NR2E1	31	Q9Y466
KITLAGYCDCFASGD	TESMIN	301	Q9Y4I5
GCYAGYRLSADGCGC	MEGF6	396	O75095
CKDYKETGFCGFGDS	RNF113B	196	Q8IZP6
ETGFCGFGDSCKFLH	RNF113B	201	Q8IZP6
NGSAACGLGYDFSRC	SLC12A1	456	Q13621
CGSLAAYGEACRSFG	TECTA	1731	O75443
GCEECGKAFSTFSYL	ZNF30	261	P17039
PYGCSECGKAFADRS	ZIM3	446	Q96PE6
YKCAECGKGFGDSSA	ZNF48	571	Q96MX3
FACADCGKAFRGSSG	ZNF497	386	Q6ZNH5
QSGEKAFRCEYDGCG	ZNF143	231	P52747
CGFDGCGSTYKNARG	RLF	956	Q13129
DFSCCLGSYGSDKVL	WDFY4	2911	Q6ZS81
RCVYSGRFGSLKSGC	STAB2	701	Q8WWQ8
CYFGATPGSGKFCRL	nan	91	Q86TA4
RFHGSCCASGFLGFF	TMEM241	216	Q24JQ0
RFGRSFTCDSCGFGF	ZBTB1	211	Q9Y2K1
FRCGECGKGFSRNTY	ZNF697	261	Q5TEC3
TGKRSYGCSECGKFF	ZNF547	291	Q8IVP9
NCPFYSKTGACRFGD	ZRSR2P1	176	Q15695
CDYCGKGFSDFSGLR	ZNF18	466	P17022
YECKECGKAFSFGSG	ZNF345	146	Q14585
NCPFYSKTGACRFGD	ZRSR2	171	Q15696
RCDFPSCGKAFATGY	ZNF76	196	P36508