Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphoglycerate kinase activity	PGK1 PGK2	1.92e-05	2	88	2	GO:0004618
GeneOntologyMolecularFunction	phosphotransferase activity, carboxyl group as acceptor	PGK1 PGK2	5.74e-05	3	88	2	GO:0016774
GeneOntologyBiologicalProcess	cell cycle process	CCNE1 USP26 KNTC1 SEPTIN8 KIF18A CEP72 CENPH ESR1 SEPTIN14 TERB1 SEPTIN11 SPO11 SYCE3 ATM ZW10 SEPTIN10 STAG2 SEPTIN6 NIN	9.94e-06	1441	89	19	GO:0022402
GeneOntologyBiologicalProcess	sexual reproduction	CCNE1 CFAP47 USP26 TSNAXIP1 KIF18A BMPR1B MTOR SMCHD1 SEPTIN14 TERB1 SPO11 ACSBG2 SYCE3 ATM ZW10 SPAG16 STAG2 SEPTIN6	1.04e-05	1312	89	18	GO:0019953
GeneOntologyBiologicalProcess	microtubule-based process	BICD2 CFAP47 KIF18A CEP72 CENPH AP3B2 DIAPH1 ZW10 SPAG16 CCDC65 LYST STAG2 PGK2 MADD BICD1 NIN	1.06e-05	1058	89	16	GO:0007017
GeneOntologyBiologicalProcess	establishment of chromosome localization	KNTC1 KIF18A TERB1 SPO11 ATM ZW10	1.47e-05	122	89	6	GO:0051303
GeneOntologyBiologicalProcess	chromosome organization involved in meiotic cell cycle	CCNE1 TERB1 SPO11 SYCE3 ATM	1.82e-05	75	89	5	GO:0070192
GeneOntologyBiologicalProcess	chromosome localization	KNTC1 KIF18A TERB1 SPO11 ATM ZW10	2.11e-05	130	89	6	GO:0050000
GeneOntologyBiologicalProcess	homologous chromosome segregation	CCNE1 TERB1 SPO11 SYCE3 ATM	2.20e-05	78	89	5	GO:0045143
GeneOntologyBiologicalProcess	nuclear chromosome segregation	CCNE1 KNTC1 KIF18A TERB1 SPO11 SYCE3 ATM ZW10 STAG2	2.32e-05	356	89	9	GO:0098813
GeneOntologyBiologicalProcess	microtubule anchoring at microtubule organizing center	BICD2 BICD1 NIN	2.73e-05	14	89	3	GO:0072393
GeneOntologyBiologicalProcess	meiotic telomere clustering	TERB1 SPO11 ATM	2.73e-05	14	89	3	GO:0045141
GeneOntologyBiologicalProcess	chromosome localization to nuclear envelope involved in homologous chromosome segregation	TERB1 SPO11 ATM	2.73e-05	14	89	3	GO:0090220
GeneOntologyBiologicalProcess	chromosome segregation	CCNE1 KNTC1 KIF18A CENPH TERB1 SPO11 SYCE3 ATM ZW10 STAG2	3.19e-05	465	89	10	GO:0007059
GeneOntologyBiologicalProcess	telomere localization	TERB1 SPO11 ATM	3.40e-05	15	89	3	GO:0034397
GeneOntologyBiologicalProcess	multicellular organismal reproductive process	CFAP47 USP26 TSNAXIP1 KIF18A BMPR1B MTOR ESR1 SMCHD1 SEPTIN14 SPO11 ACSBG2 SYCE3 ATM DMD SPAG16 SEPTIN6	4.63e-05	1194	89	16	GO:0048609
GeneOntologyBiologicalProcess	organelle localization	BICD2 KNTC1 KIF18A MTOR AP3B2 TERB1 SPO11 ATM DMD ZW10 MADD BICD1	4.81e-05	703	89	12	GO:0051640
GeneOntologyBiologicalProcess	regulation of autophagosome assembly	PHF23 MTOR ATM SCFD1	6.41e-05	50	89	4	GO:2000785
GeneOntologyBiologicalProcess	nuclear division	CCNE1 KNTC1 KIF18A ESR1 TERB1 SPO11 SYCE3 ATM ZW10 STAG2	7.15e-05	512	89	10	GO:0000280
GeneOntologyBiologicalProcess	gamete generation	CFAP47 USP26 TSNAXIP1 KIF18A BMPR1B MTOR SMCHD1 SEPTIN14 SPO11 ACSBG2 SYCE3 ATM SPAG16 SEPTIN6	7.63e-05	982	89	14	GO:0007276
GeneOntologyBiologicalProcess	organelle assembly	CFAP47 KNTC1 EIF4ENIF1 PHF23 CEP72 MTOR TBC1D1 CENPH ATM SCFD1 SPAG16 CCDC65 STAG2 SEPTIN6 BICD1	9.93e-05	1138	89	15	GO:0070925
GeneOntologyBiologicalProcess	minus-end-directed organelle transport along microtubule	BICD2 BICD1	1.10e-04	4	89	2	GO:0072385
GeneOntologyBiologicalProcess	establishment of organelle localization	BICD2 KNTC1 KIF18A AP3B2 TERB1 SPO11 ATM ZW10 MADD BICD1	1.21e-04	546	89	10	GO:0051656
GeneOntologyBiologicalProcess	homologous chromosome pairing at meiosis	CCNE1 TERB1 SPO11 SYCE3	1.31e-04	60	89	4	GO:0007129
GeneOntologyBiologicalProcess	meiotic cell cycle	CCNE1 KIF18A TERB1 SPO11 SYCE3 ATM ZW10 STAG2	1.36e-04	350	89	8	GO:0051321
GeneOntologyBiologicalProcess	regulation of vacuole organization	PHF23 MTOR ATM SCFD1	1.40e-04	61	89	4	GO:0044088
GeneOntologyBiologicalProcess	microtubule anchoring	BICD2 BICD1 NIN	1.67e-04	25	89	3	GO:0034453
GeneOntologyBiologicalProcess	negative regulation of mitotic nuclear division	KNTC1 ESR1 ATM ZW10	1.69e-04	64	89	4	GO:0045839
GeneOntologyBiologicalProcess	organelle fission	CCNE1 KNTC1 KIF18A ESR1 TERB1 SPO11 SYCE3 ATM ZW10 STAG2	1.75e-04	571	89	10	GO:0048285
GeneOntologyBiologicalProcess	chromosome organization	CCNE1 KNTC1 KIF18A CENPH SMCHD1 TERB1 SPO11 SYCE3 ATM ZW10 STAG2	1.76e-04	686	89	11	GO:0051276
GeneOntologyBiologicalProcess	meiotic chromosome segregation	CCNE1 TERB1 SPO11 SYCE3 ATM	1.86e-04	122	89	5	GO:0045132
GeneOntologyBiologicalProcess	reciprocal meiotic recombination	TERB1 SPO11 SYCE3 ATM	2.02e-04	67	89	4	GO:0007131
GeneOntologyBiologicalProcess	reciprocal homologous recombination	TERB1 SPO11 SYCE3 ATM	2.02e-04	67	89	4	GO:0140527
GeneOntologyBiologicalProcess	cytoskeleton-dependent cytokinesis	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.24e-04	127	89	5	GO:0061640
GeneOntologyBiologicalProcess	developmental process involved in reproduction	CFAP47 USP26 TSNAXIP1 KIF18A BMPR1B MTOR ESR1 SMCHD1 SEPTIN14 SPO11 ACSBG2 SYCE3 ATM SPAG16 SEPTIN6	2.43e-04	1235	89	15	GO:0003006
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	BICD2 CFAP47 KIF18A CEP72 CENPH ZW10 SPAG16 CCDC65 STAG2 BICD1 NIN	2.67e-04	720	89	11	GO:0000226
GeneOntologyBiologicalProcess	negative regulation of monoatomic anion transport	MTOR PRKG2	2.73e-04	6	89	2	GO:1903792
GeneOntologyBiologicalProcess	microtubule-based movement	BICD2 CFAP47 KIF18A AP3B2 SPAG16 CCDC65 PGK2 MADD BICD1	2.77e-04	493	89	9	GO:0007018
GeneOntologyBiologicalProcess	negative regulation of nuclear division	KNTC1 ESR1 ATM ZW10	2.81e-04	73	89	4	GO:0051784
GeneOntologyBiologicalProcess	homologous recombination	TERB1 SPO11 SYCE3 ATM	2.96e-04	74	89	4	GO:0035825
GeneOntologyBiologicalProcess	male gamete generation	CFAP47 USP26 TSNAXIP1 KIF18A SEPTIN14 SPO11 ACSBG2 SYCE3 ATM SPAG16 SEPTIN6	4.31e-04	762	89	11	GO:0048232
GeneOntologyBiologicalProcess	meiosis I	CCNE1 TERB1 SPO11 SYCE3 ATM	4.41e-04	147	89	5	GO:0007127
GeneOntologyBiologicalProcess	negative regulation of macroautophagy	PHF23 MTOR SCFD1	4.60e-04	35	89	3	GO:0016242
GeneOntologyBiologicalProcess	cyclic-GMP-AMP transmembrane import across plasma membrane	LRRC8B SHOC2	5.07e-04	8	89	2	GO:0140361
GeneOntologyBiologicalProcess	negative regulation of endoplasmic reticulum calcium ion concentration	THADA RAP1GDS1	5.07e-04	8	89	2	GO:0032471
GeneOntologyBiologicalProcess	ovarian follicle development	BMPR1B ESR1 SPO11 ATM	5.49e-04	87	89	4	GO:0001541
GeneOntologyBiologicalProcess	meiosis I cell cycle process	CCNE1 TERB1 SPO11 SYCE3 ATM	5.61e-04	155	89	5	GO:0061982
GeneOntologyBiologicalProcess	meiotic nuclear division	CCNE1 KIF18A TERB1 SPO11 SYCE3 ATM	6.06e-04	240	89	6	GO:0140013
GeneOntologyBiologicalProcess	guanine nucleotide transmembrane transport	LRRC8B SHOC2	8.10e-04	10	89	2	GO:1903790
GeneOntologyBiologicalProcess	organelle transport along microtubule	BICD2 AP3B2 MADD BICD1	8.27e-04	97	89	4	GO:0072384
GeneOntologyBiologicalProcess	cell division	CCNE1 KNTC1 SEPTIN8 SEPTIN14 SEPTIN11 SYCE3 ZW10 SEPTIN10 STAG2 SEPTIN6	8.36e-04	697	89	10	GO:0051301
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	IBTK THADA RAP1GDS1 ERC1 DIAPH1 DMD INPP4B	9.26e-04	359	89	7	GO:0006874
GeneOntologyBiologicalProcess	cyclic nucleotide transport	LRRC8B SHOC2	9.87e-04	11	89	2	GO:0070729
GeneOntologyBiologicalProcess	guanine nucleotide transport	LRRC8B SHOC2	9.87e-04	11	89	2	GO:0001408
GeneOntologyBiologicalProcess	cellular homeostasis	IBTK THADA RAP1GDS1 ERC1 ZBED6 TBC1D1 CMA1 DIAPH1 PRKG2 DMD INPP4B KRIT1	1.02e-03	981	89	12	GO:0019725
GeneOntologyBiologicalProcess	meiotic cell cycle process	CCNE1 KIF18A TERB1 SPO11 SYCE3 ATM	1.07e-03	268	89	6	GO:1903046
GeneOntologyBiologicalProcess	germ cell development	CFAP47 BMPR1B MTOR SMCHD1 SEPTIN14 SPO11 ATM SPAG16	1.13e-03	482	89	8	GO:0007281
GeneOntologyCellularComponent	septin complex	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.43e-09	14	89	5	GO:0031105
GeneOntologyCellularComponent	septin ring	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.43e-09	14	89	5	GO:0005940
GeneOntologyCellularComponent	septin cytoskeleton	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	5.26e-09	16	89	5	GO:0032156
GeneOntologyCellularComponent	chromosomal region	KNTC1 KIF18A CENPH SMCHD1 TERB1 SPO11 ATM ZW10 STAG2 SEPTIN6	1.22e-05	421	89	10	GO:0098687
GeneOntologyCellularComponent	cell division site	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.33e-05	80	89	5	GO:0032153
GeneOntologyCellularComponent	RZZ complex	KNTC1 ZW10	5.36e-05	3	89	2	GO:1990423
GeneOntologyCellularComponent	kinetochore microtubule	KNTC1 KIF18A ZW10	1.08e-04	22	89	3	GO:0005828
GeneOntologyCellularComponent	sperm annulus	SEPTIN10 SEPTIN6	6.33e-04	9	89	2	GO:0097227
GeneOntologyCellularComponent	motile cilium	CFAP47 USP26 SPAG16 SEPTIN10 CCDC65 PGK2 SEPTIN6	8.03e-04	355	89	7	GO:0031514
GeneOntologyCellularComponent	spindle	KNTC1 KIF18A DIAPH1 ATM ZW10 STAG2 SEPTIN6 NIN	8.97e-04	471	89	8	GO:0005819
GeneOntologyCellularComponent	cell cortex	SEPTIN8 MYO9B ERC1 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	1.04e-03	371	89	7	GO:0005938
GeneOntologyCellularComponent	kinetochore	KNTC1 KIF18A CENPH ZW10 SEPTIN6	1.06e-03	181	89	5	GO:0000776
GeneOntologyCellularComponent	chromosome, centromeric region	KNTC1 KIF18A CENPH ZW10 STAG2 SEPTIN6	1.17e-03	276	89	6	GO:0000775
GeneOntologyCellularComponent	fascia adherens	DSP TLN2	1.36e-03	13	89	2	GO:0005916
GeneOntologyCellularComponent	condensed chromosome, centromeric region	KNTC1 KIF18A CENPH ZW10 SEPTIN6	1.41e-03	193	89	5	GO:0000779
GeneOntologyCellularComponent	centrosome	CCNE1 BICD2 KIF18A CEP72 ERC1 ZBED6 DIAPH1 ATM BICD1 NIN	1.60e-03	770	89	10	GO:0005813
GeneOntologyCellularComponent	microtubule organizing center	CCNE1 BICD2 KIF18A CEP72 ERC1 ZBED6 DIAPH1 ATM CCDC65 BICD1 NIN	1.78e-03	919	89	11	GO:0005815
GeneOntologyCellularComponent	synaptic vesicle	SEPTIN8 ERC1 ATM DMD SEPTIN6 MADD	1.78e-03	300	89	6	GO:0008021
GeneOntologyCellularComponent	condensed chromosome	KNTC1 KIF18A CENPH SYCE3 ZW10 SEPTIN6	2.00e-03	307	89	6	GO:0000793
GeneOntologyCellularComponent	sperm flagellum	USP26 SPAG16 SEPTIN10 PGK2 SEPTIN6	2.22e-03	214	89	5	GO:0036126
GeneOntologyCellularComponent	secretory vesicle	SEPTIN8 DSP ABCA13 ERC1 SEPTIN14 CMA1 DIAPH1 PSMD11 ATM DMD SEPTIN6 MADD BICD1	2.31e-03	1246	89	13	GO:0099503
GeneOntologyCellularComponent	exocytic vesicle	SEPTIN8 ERC1 ATM DMD SEPTIN6 MADD	2.46e-03	320	89	6	GO:0070382
GeneOntologyCellularComponent	9+2 motile cilium	USP26 SPAG16 SEPTIN10 PGK2 SEPTIN6	3.50e-03	238	89	5	GO:0097729
Domain	Septin	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.59e-09	13	88	5	PF00735
Domain	G_SEPTIN_dom	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.59e-09	13	88	5	IPR030379
Domain	G_SEPTIN	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.59e-09	13	88	5	PS51719
Domain	Septin	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	4.01e-09	14	88	5	IPR016491
Domain	ARM-type_fold	THADA RAP1GDS1 MROH1 MTOR UNC45B AP3B2 DIAPH1 TERB1 ATM LYST STAG2	5.52e-07	339	88	11	IPR016024
Domain	PGLYCERATE_KINASE	PGK1 PGK2	2.19e-05	2	88	2	PS00111
Domain	Phosphoglycerate_kinase_N	PGK1 PGK2	2.19e-05	2	88	2	IPR015824
Domain	Phosphoglycerate_kinase_CS	PGK1 PGK2	2.19e-05	2	88	2	IPR015911
Domain	Phosphoglycerate_kinase_C	PGK1 PGK2	2.19e-05	2	88	2	IPR015901
Domain	Bicaudal-D_microtubule-assoc	BICD2 BICD1	2.19e-05	2	88	2	IPR018477
Domain	-	PGK1 PGK2	2.19e-05	2	88	2	3.40.50.1270
Domain	-	PGK1 PGK2	2.19e-05	2	88	2	3.40.50.1260
Domain	PGK	PGK1 PGK2	2.19e-05	2	88	2	PF00162
Domain	BicD	BICD2 BICD1	2.19e-05	2	88	2	PF09730
Domain	Phosphoglycerate_kinase	PGK1 PGK2	6.56e-05	3	88	2	IPR001576
Domain	FATC	MTOR ATM	2.17e-04	5	88	2	PF02260
Domain	ARM-like	RAP1GDS1 MROH1 MTOR UNC45B AP3B2 TERB1 STAG2	2.86e-04	270	88	7	IPR011989
Domain	FAT	MTOR ATM	3.25e-04	6	88	2	PS51189
Domain	FATC	MTOR ATM	3.25e-04	6	88	2	PS51190
Domain	FAT	MTOR ATM	3.25e-04	6	88	2	PF02259
Domain	PIK-rel_kinase_FAT	MTOR ATM	3.25e-04	6	88	2	IPR003151
Domain	FATC_dom	MTOR ATM	3.25e-04	6	88	2	IPR003152
Domain	PIK_FAT	MTOR ATM	3.25e-04	6	88	2	IPR014009
Domain	FATC	MTOR ATM	3.25e-04	6	88	2	SM01343
Domain	Spectrin_repeat	DSP MCF2 DMD	3.38e-04	29	88	3	IPR002017
Domain	Spectrin/alpha-actinin	DSP MCF2 DMD	4.54e-04	32	88	3	IPR018159
Domain	SPEC	DSP MCF2 DMD	4.54e-04	32	88	3	SM00150
Domain	-	RAP1GDS1 MROH1 MTOR UNC45B AP3B2 TERB1	6.35e-04	222	88	6	1.25.10.10
Domain	DEATH-like_dom	CASP10 IFI16 MADD NLRP8	1.23e-03	99	88	4	IPR011029
Domain	WW	WWC2 WWP1 DMD	1.41e-03	47	88	3	PF00397
Domain	WW	WWC2 WWP1 DMD	1.50e-03	48	88	3	SM00456
Domain	WW_DOMAIN_2	WWC2 WWP1 DMD	1.79e-03	51	88	3	PS50020
Domain	WW_DOMAIN_1	WWC2 WWP1 DMD	1.79e-03	51	88	3	PS01159
Domain	WW_dom	WWC2 WWP1 DMD	1.89e-03	52	88	3	IPR001202
Domain	P-loop_NTPase	SEPTIN8 KIF18A PALS1 MYO9B ABCA13 N4BP2 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6 NLRP8	2.08e-03	848	88	11	IPR027417
Domain	PI3/4_kinase_CS	MTOR ATM	2.21e-03	15	88	2	IPR018936
Domain	-	MTOR ATM	2.52e-03	16	88	2	1.10.1070.11
Domain	PI3Kc	MTOR ATM	2.52e-03	16	88	2	SM00146
Domain	PI3/4_kinase_cat_dom	MTOR ATM	3.20e-03	18	88	2	IPR000403
Domain	PI3_PI4_kinase	MTOR ATM	3.20e-03	18	88	2	PF00454
Domain	PI3_4_KINASE_3	MTOR ATM	3.20e-03	18	88	2	PS50290
Domain	PI3_4_KINASE_1	MTOR ATM	3.20e-03	18	88	2	PS00915
Domain	PI3_4_KINASE_2	MTOR ATM	3.20e-03	18	88	2	PS00916
Domain	Kinase-like_dom	TNNI3K BMPR1B MTOR ATM PRKG2 DMD MAPK10 PRDM2	4.02e-03	542	88	8	IPR011009
Domain	Ank	TNNI3K IBTK ANKRD30A ANKRD30B KRIT1	4.47e-03	228	88	5	PF00023
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	CCNE1 KNTC1 KIF18A CENPH PSMD11 ATM ZW10	2.41e-04	271	65	7	MM15388
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	KNTC1 KIF18A CENPH PSMD11 ZW10 STAG2	2.43e-04	191	65	6	M29614
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	KNTC1 KIF18A CENPH PSMD11 ZW10 STAG2	2.57e-04	193	65	6	MM14890
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	KNTC1 KIF18A CENPH ZW10 STAG2	2.94e-04	127	65	5	M27181
Pathway	REACTOME_CELL_CYCLE	CCNE1 KNTC1 KIF18A CEP72 CENPH SPO11 SYCE3 PSMD11 ATM ZW10 STAG2	2.99e-04	694	65	11	M543
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	KNTC1 KIF18A CENPH ZW10 STAG2	3.16e-04	129	65	5	MM14894
Pathway	REACTOME_MITOTIC_PROMETAPHASE	KNTC1 KIF18A CEP72 CENPH ZW10 STAG2	3.29e-04	202	65	6	MM15362
Pathway	REACTOME_MITOTIC_PROMETAPHASE	KNTC1 KIF18A CEP72 CENPH ZW10 STAG2	3.46e-04	204	65	6	M4217
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	CCNE1 KNTC1 KIF18A CENPH PSMD11 ATM ZW10	3.72e-04	291	65	7	M16647
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	CCNE1 KNTC1 KIF18A RAP1GDS1 DSP MYO9B CENPH DIAPH1 MCF2 SCFD1 ZW10	4.09e-04	720	65	11	M41838
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	KNTC1 KIF18A CENPH DIAPH1 ZW10	4.60e-04	140	65	5	M27550
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	KNTC1 KIF18A CENPH DIAPH1 ZW10	4.76e-04	141	65	5	MM15266
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	4.43e-10	16	90	5	22575789
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KNTC1 BMPR1B CUX2 DSP ERC1 N4BP2 SMCHD1 ANKRD30A CCDC150 ANKRD30B ATM DMD SEPTIN10 LYST PGK1 STAG2 PGK2	1.53e-07	1442	90	17	35575683
Pubmed	Androglobin, a chimeric mammalian globin, is required for male fertility.	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10	1.58e-07	19	90	4	35700329
Pubmed	MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.	USP26 SPO11 ATM PGK1	6.00e-07	26	90	4	35920200
Pubmed	Septin 14 is involved in cortical neuronal migration via interaction with Septin 4.	SEPTIN14 SEPTIN11 SEPTIN6	9.30e-07	8	90	3	20181826
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	BICD2 SEPTIN8 DSP ERC1 SEPTIN11 TLN2 PSMD11 EDC4 SEPTIN10 SHOC2 LRP1B PGK1 SEPTIN6 MADD	1.34e-06	1139	90	14	36417873
Pubmed	The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis.	TERB1 SPO11 SYCE3	1.39e-06	9	90	3	24413433
Pubmed	GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome.	BICD2 BICD1 NIN	1.39e-06	9	90	3	17139249
Pubmed	Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.	SEPTIN8 SEPTIN11 SEPTIN6	1.39e-06	9	90	3	18809578
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	KNTC1 SEPTIN8 DSP ERC1 AP3B2 SEPTIN11 TLN2 PSMD11 SEPTIN10 PGK1 PGK2 SEPTIN6	1.94e-06	847	90	12	35235311
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	BICD2 SEPTIN8 IBTK EIF4ENIF1 DSP ERC1 N4BP2 TBC1D1 LRP1B SEPTIN6 BICD1 NIN	2.08e-06	853	90	12	28718761
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DSP SMCHD1 DIAPH1 TLN2 PSMD11 ATM EDC4 SHOC2 USP48 STAG2	2.75e-06	582	90	10	20467437
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	SEPTIN8 BMPR1B THADA RAP1GDS1 MROH1 SMCHD1 WWP1 SEPTIN11 PSMD11 ATM SCFD1 ZW10 SEPTIN10	3.45e-06	1061	90	13	33845483
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	AUH DSP SMCHD1 TLN2 LRRC8B SHOC2 PGK1 MADD KRIT1	4.07e-06	475	90	9	31040226
Pubmed	The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action.	ESR1 PRDM2	6.62e-06	2	90	2	10706618
Pubmed	A factor stimulating transcription of the testis-specific Pgk-2 gene recognizes a sequence similar to the binding site for a transcription inhibitor of the somatic-type Pgk-1 gene.	PGK1 PGK2	6.62e-06	2	90	2	8441629
Pubmed	Mammalian meiosis involves DNA double-strand breaks with 3' overhangs.	SPO11 ATM	6.62e-06	2	90	2	12644952
Pubmed	MED15 overexpression in prostate cancer arises during androgen deprivation therapy via PI3K/mTOR signaling.	MED15 MTOR	6.62e-06	2	90	2	27974704
Pubmed	Estrogen receptor alpha prevents bladder cancer via INPP4B inhibited akt pathway in vitro and in vivo.	ESR1 INPP4B	6.62e-06	2	90	2	25277204
Pubmed	Aurora B kinase-dependent recruitment of hZW10 and hROD to tensionless kinetochores.	KNTC1 ZW10	6.62e-06	2	90	2	18065224
Pubmed	The family of mouse phosphoglycerate kinase genes and pseudogenes.	PGK1 PGK2	6.62e-06	2	90	2	2829366
Pubmed	STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition.	ATM STAG2	6.62e-06	2	90	2	37985839
Pubmed	Characterization of phosphoglycerate kinase from human spermatozoa.	PGK1 PGK2	6.62e-06	2	90	2	1278465
Pubmed	The impact of estradiol on bone mineral density is modulated by the specific estrogen receptor-alpha cofactor retinoblastoma-interacting zinc finger protein-1 insertion/deletion polymorphism.	ESR1 PRDM2	6.62e-06	2	90	2	17356055
Pubmed	De novo deletions and duplications at recombination hotspots in mouse germlines.	SPO11 ATM	6.62e-06	2	90	2	34793701
Pubmed	Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.	PGK1 PGK2	6.62e-06	2	90	2	9023984
Pubmed	Regulation of AGR2 expression via 3'UTR shortening.	MTOR AGR2	6.62e-06	2	90	2	28408318
Pubmed	The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study.	ESR1 PRDM2	6.62e-06	2	90	2	18037365
Pubmed	Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.	PGK1 PGK2	6.62e-06	2	90	2	3453121
Pubmed	Transcription switch of two phosphoglycerate kinase genes during spermatogenesis as determined with mouse testis sections in situ.	PGK1 PGK2	6.62e-06	2	90	2	2298243
Pubmed	ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes.	SPO11 ATM	6.62e-06	2	90	2	18497861
Pubmed	Selective activation of testis-specific genes in cultured rat spermatogenic cells.	PGK1 PGK2	6.62e-06	2	90	2	2166582
Pubmed	Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.	MTOR DMD	6.62e-06	2	90	2	23115080
Pubmed	Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice.	DMD PGK1	6.62e-06	2	90	2	2919177
Pubmed	A deletion polymorphism in the RIZ gene, a female sex steroid hormone receptor coactivator, exhibits decreased response to estrogen in vitro and associates with low bone mineral density in young Swedish women.	ESR1 PRDM2	6.62e-06	2	90	2	15579774
Pubmed	Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme.	PGK1 PGK2	6.62e-06	2	90	2	5009693
Pubmed	The ZW10 and Rough Deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore.	KNTC1 ZW10	6.62e-06	2	90	2	11590237
Pubmed	Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse.	PGK1 PGK2	6.62e-06	2	90	2	8662942
Pubmed	Neuronal Roles of the Bicaudal D Family of Motor Adaptors.	BICD2 BICD1	6.62e-06	2	90	2	28215293
Pubmed	MS-KIF18A, a kinesin, is associated with estrogen receptor.	KIF18A ESR1	6.62e-06	2	90	2	17006958
Pubmed	Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library.	ANKRD30A ANKRD30B	6.62e-06	2	90	2	11280766
Pubmed	Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores.	KNTC1 ZW10	6.62e-06	2	90	2	11146660
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MED15 KIF18A THADA EIF4ENIF1 MTOR ERC1 TBC1D1 CENPH CCDC150 SEPTIN11 PRKG2 ZW10 SPAG16 SHOC2	7.40e-06	1321	90	14	27173435
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SEPTIN8 ERC1 SEPTIN11 SEPTIN10 SEPTIN6	9.37e-06	108	90	5	19531213
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	RAP1GDS1 ERC1 TBC1D1 EDC4 PGK2 BICD1 NIN	9.64e-06	285	90	7	32838362
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	MTOR DIAPH1 SEPTIN11 PSMD11 DMD SEPTIN10 PGK1 SEPTIN6 MADD	1.10e-05	538	90	9	28524877
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	KNTC1 DSP MYO9B MTOR SMCHD1 ANKRD30A	1.48e-05	202	90	6	33005030
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 THADA DSP MTOR SMCHD1 DIAPH1 TLN2 PSMD11 ATM SCFD1 EDC4 PGK1 STAG2 PRDM2	1.73e-05	1425	90	14	30948266
Pubmed	Phosphorylated tau interactome in the human Alzheimer's disease brain.	SEPTIN8 AP3B2 SEPTIN11 PSMD11 SEPTIN6	1.90e-05	125	90	5	32812023
Pubmed	SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres.	SMCHD1 ATM	1.98e-05	3	90	2	32080884
Pubmed	FGFR1 Amplification Mediates Endocrine Resistance but Retains TORC Sensitivity in Metastatic Hormone Receptor-Positive (HR+) Breast Cancer.	MTOR ESR1	1.98e-05	3	90	2	31371343
Pubmed	Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene.	PGK1 PGK2	1.98e-05	3	90	2	1380672
Pubmed	Mammalian septins nomenclature.	SEPTIN8 SEPTIN10	1.98e-05	3	90	2	12475938
Pubmed	Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily.	ESR1 PRDM2	1.98e-05	3	90	2	11544182
Pubmed	mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation.	MTOR ESR1	1.98e-05	3	90	2	26522726
Pubmed	Binding of anterior gradient 2 and estrogen receptor-α: Dual critical roles in enhancing fulvestrant resistance and IGF-1-induced tumorigenesis of breast cancer.	ESR1 AGR2	1.98e-05	3	90	2	27063095
Pubmed	Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5.	SEPTIN8 SEPTIN11	1.98e-05	3	90	2	16767699
Pubmed	Structure of the RZZ complex and molecular basis of its interaction with Spindly.	KNTC1 ZW10	1.98e-05	3	90	2	28320825
Pubmed	Kinase-independent function of E-type cyclins in liver cancer.	CCNE1 ESR1	1.98e-05	3	90	2	29339491
Pubmed	Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice.	MTOR ESR1	1.98e-05	3	90	2	28789972
Pubmed	Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.	DMD LYST	1.98e-05	3	90	2	29242210
Pubmed	Septin expression in proliferative retinal membranes.	SEPTIN8 SEPTIN11	1.98e-05	3	90	2	17625225
Pubmed	Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2.	ESR1 PRDM2	1.98e-05	3	90	2	19746436
Pubmed	Reconstitution of the targeting of Rab6A to the Golgi apparatus in semi-intact HeLa cells: A role of BICD2 in stabilizing Rab6A on Golgi membranes and a concerted role of Rab6A/BICD2 interactions in Golgi-to-ER retrograde transport.	BICD2 BICD1	1.98e-05	3	90	2	25962623
Pubmed	Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis.	ESR1 PRDM2	1.98e-05	3	90	2	20508921
Pubmed	microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity.	MTOR ESR1	1.98e-05	3	90	2	25283550
Pubmed	Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.	SPO11 ATM	1.98e-05	3	90	2	26209650
Pubmed	The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons.	BMPR1B ERC1	1.98e-05	3	90	2	25209271
Pubmed	Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes.	MTOR TBC1D1	1.98e-05	3	90	2	18215134
Pubmed	ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis.	MTOR ATM	1.98e-05	3	90	2	22362778
Pubmed	Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.	KNTC1 ZW10	1.98e-05	3	90	2	12686595
Pubmed	A segregating human allele of SPO11 modeled in mice disrupts timing and amounts of meiotic recombination, causing oligospermia and a decreased ovarian reserve†.	SPO11 ATM	1.98e-05	3	90	2	31074776
Pubmed	Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex.	KNTC1 ZW10	1.98e-05	3	90	2	25849506
Pubmed	mTOR-mediated phosphorylation of VAMP8 and SCFD1 regulates autophagosome maturation.	MTOR SCFD1	1.98e-05	3	90	2	34785650
Pubmed	Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.	MTOR ATM	1.98e-05	3	90	2	21641396
Pubmed	ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.	MTOR ATM	1.98e-05	3	90	2	20160076
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BICD2 KNTC1 DSP MYO9B ERC1 N4BP2 CENPH DIAPH1 NIN	2.22e-05	588	90	9	38580884
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CUX2 CEP72 ERC1 TBC1D1 TLN2 NIN	2.71e-05	225	90	6	12168954
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MED15 KNTC1 SMCHD1 SEPTIN14 PSMD11 EDC4 ZW10 IFI16 PGK1 STAG2 SEPTIN6 PRDM2	2.74e-05	1103	90	12	34189442
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	BICD2 MYO9B PSMD11 BICD1 NIN	3.17e-05	139	90	5	25476789
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	KNTC1 DSP AP3B2 LYST	3.77e-05	72	90	4	25917818
Pubmed	IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway.	ATM IFI16	3.96e-05	4	90	2	21573174
Pubmed	Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex.	BICD2 BICD1	3.96e-05	4	90	2	12447383
Pubmed	SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.	SPO11 ATM	3.96e-05	4	90	2	15998665
Pubmed	Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage.	SPO11 ATM	3.96e-05	4	90	2	16055729
Pubmed	Luminal breast cancer cell lines overexpressing ZNF703 are resistant to tamoxifen through activation of Akt/mTOR signaling.	MTOR ESR1	3.96e-05	4	90	2	23991038
Pubmed	ATM controls meiotic double-strand-break formation.	SPO11 ATM	3.96e-05	4	90	2	22002603
Pubmed	Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.	MTOR PGK1	3.96e-05	4	90	2	26356530
Pubmed	mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.	MTOR ATM	3.96e-05	4	90	2	21095582
Pubmed	Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.	MTOR DMD	3.96e-05	4	90	2	25139234
Pubmed	MetaLnc9 Facilitates Lung Cancer Metastasis via a PGK1-Activated AKT/mTOR Pathway.	MTOR PGK1	3.96e-05	4	90	2	28923857
Pubmed	ATM binds to beta-adaptin in cytoplasmic vesicles.	AP3B2 ATM	3.96e-05	4	90	2	9707615
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	MED15 KIF18A CEP72 ERC1 SMCHD1 DIAPH1 EDC4 USP48 NIN	4.56e-05	645	90	9	25281560
Pubmed	Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.	DIAPH1 SEPTIN11 PSMD11 SCFD1 ZW10 SEPTIN6	6.46e-05	263	90	6	12665801
Pubmed	Septins regulate bacterial entry into host cells.	SEPTIN11 SEPTIN6	6.59e-05	5	90	2	19145258
Pubmed	Molecular and genetic mapping of the mouse mdx locus.	DMD PGK1	6.59e-05	5	90	2	3243547
Pubmed	Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells.	SPO11 ATM	6.59e-05	5	90	2	21355037
Pubmed	The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.	SPO11 ATM	6.59e-05	5	90	2	24532689
Pubmed	Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling.	CCNE1 ESR1	6.59e-05	5	90	2	26676054
Pubmed	Non-tumorigenic epithelial cells secrete MCP-1 and other cytokines that promote cell division in breast cancer cells by activating ERα via PI3K/Akt/mTOR signaling.	MTOR ESR1	6.59e-05	5	90	2	24878609
Interaction	SEPTIN6 interactions	BICD2 SEPTIN8 RAP1GDS1 CEP72 SEPTIN14 AGR2 SEPTIN11 SEPTIN10 SEPTIN6	2.01e-10	88	90	9	int:SEPTIN6
Interaction	SEPTIN10 interactions	SEPTIN8 RAP1GDS1 ERC1 N4BP2 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6 NIN	1.63e-08	144	90	9	int:SEPTIN10
Interaction	SEPTIN11 interactions	SEPTIN8 CEP72 ESR1 SEPTIN14 SEPTIN11 SEPTIN10 USP48 SEPTIN6	7.33e-08	122	90	8	int:SEPTIN11
Interaction	SEPTIN12 interactions	SEPTIN8 RAP1GDS1 SEPTIN11 SEPTIN10 SEPTIN6	9.70e-08	26	90	5	int:SEPTIN12
Interaction	SEPTIN8 interactions	BICD2 SEPTIN8 ESR1 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	1.22e-07	87	90	7	int:SEPTIN8
Interaction	SEPTIN2 interactions	SEPTIN8 RAP1GDS1 MTOR ESR1 SEPTIN14 AGR2 SEPTIN11 SEPTIN10 SEPTIN6	1.49e-07	186	90	9	int:SEPTIN2
Interaction	PDIA3 interactions	BICD2 CFAP47 THADA DSP MYO9B MTOR ESR1 AGR2 DIAPH1 USP48 PGK1 PRDM2 FILIP1L	1.90e-07	476	90	13	int:PDIA3
Interaction	SEPTIN5 interactions	SEPTIN8 ESR1 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	3.37e-07	62	90	6	int:SEPTIN5
Interaction	SEPTIN14 interactions	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	3.41e-07	33	90	5	int:SEPTIN14
Interaction	SEPTIN3 interactions	SEPTIN8 ESR1 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	4.91e-07	66	90	6	int:SEPTIN3
Interaction	KRT8 interactions	BICD2 THADA EIF4ENIF1 DSP CEP72 ERC1 N4BP2 ESR1 AGR2 DMD SEPTIN10 NIN	6.08e-07	441	90	12	int:KRT8
Interaction	RGS3 interactions	SEPTIN8 CEP72 ESR1 SEPTIN11 SEPTIN10 STAG2	6.98e-07	70	90	6	int:RGS3
Interaction	SEPTIN4 interactions	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	7.09e-07	38	90	5	int:SEPTIN4
Interaction	ACAP3 interactions	SEPTIN8 SEPTIN11 SEPTIN10 SEPTIN6	2.10e-06	21	90	4	int:ACAP3
Interaction	SPAG5 interactions	EIF4ENIF1 CENPH AGR2 ANKRD30A SYCE3 ZW10 SEPTIN10 NIN	2.62e-06	195	90	8	int:SPAG5
Interaction	DCTN2 interactions	BICD2 CEP72 ERC1 N4BP2 CENPH ZW10 IFI16 USP48 BICD1 NIN	4.26e-06	356	90	10	int:DCTN2
Interaction	CEP128 interactions	BICD2 PALS1 IBTK EIF4ENIF1 DSP CEP72 ERC1 BICD1 NIN	7.22e-06	297	90	9	int:CEP128
Interaction	SEPTIN7 interactions	BICD2 SEPTIN8 SMCHD1 SEPTIN14 SEPTIN11 SEPTIN10 USP48 SEPTIN6	8.29e-06	228	90	8	int:SEPTIN7
Interaction	SCLT1 interactions	EIF4ENIF1 ERC1 CENPH ANKRD30A SYCE3 BICD1 NIN	1.07e-05	169	90	7	int:SCLT1
Interaction	EFNA4 interactions	KNTC1 THADA DSP CENPH ATM EDC4 ZW10 STAG2	1.17e-05	239	90	8	int:EFNA4
Interaction	PFN1 interactions	KNTC1 THADA MYO9B ERC1 N4BP2 ESR1 AGR2 CMA1 DIAPH1 USP48 PGK1	1.65e-05	509	90	11	int:PFN1
Interaction	PXN interactions	BICD2 KNTC1 ERC1 N4BP2 ESR1 DIAPH1 ZW10 BICD1 NIN	1.84e-05	334	90	9	int:PXN
Interaction	SHOC2 interactions	MTOR ESR1 SHOC2 THUMPD2 PGK1	2.01e-05	74	90	5	int:SHOC2
Interaction	FAM234A interactions	KNTC1 THADA MTOR ATM ZW10 STAG2	2.15e-05	126	90	6	int:FAM234A
Interaction	PCM1 interactions	BICD2 IBTK DSP CEP72 ERC1 ESR1 SEPTIN10 CCDC65 BICD1 NIN	2.38e-05	434	90	10	int:PCM1
Interaction	SEPTIN9 interactions	BICD2 SEPTIN8 SEPTIN14 AGR2 SEPTIN11 SEPTIN10 INPP4B SEPTIN6	2.46e-05	265	90	8	int:SEPTIN9
Interaction	HDAC4 interactions	BICD2 AUH ESR1 SMCHD1 AGR2 DIAPH1 TLN2 LRRC8B ATM SHOC2 PGK1 MADD KRIT1	2.55e-05	744	90	13	int:HDAC4
Interaction	CDC42EP4 interactions	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	2.59e-05	78	90	5	int:CDC42EP4
Interaction	CD80 interactions	KNTC1 THADA MTOR ATM ZW10	2.76e-05	79	90	5	int:CD80
Interaction	BRCA1 interactions	CCNE1 CFAP47 KNTC1 KIF18A DSP CEP72 MTOR ERC1 ESR1 SMCHD1 DIAPH1 PSMD11 ATM SEPTIN10 IFI16 USP48 PGK1	3.30e-05	1249	90	17	int:BRCA1
Interaction	H2AP interactions	KNTC1 MTOR CENPH ATM SEPTIN10	3.30e-05	82	90	5	int:H2AP
Interaction	NPTN interactions	KNTC1 THADA MROH1 MTOR ATM EDC4 ZW10 STAG2	3.46e-05	278	90	8	int:NPTN
Interaction	KRT19 interactions	EIF4ENIF1 DSP CEP72 ERC1 ESR1 DMD BICD1 NIN	3.83e-05	282	90	8	int:KRT19
Interaction	SEPTIN1 interactions	SEPTIN8 SEPTIN11 SEPTIN10 SEPTIN6	5.26e-05	46	90	4	int:SEPTIN1
Interaction	PPP2R3A interactions	BICD2 ESR1 BICD1 NIN	5.73e-05	47	90	4	int:PPP2R3A
Interaction	SCN2B interactions	KNTC1 THADA MTOR ATM ZW10	6.70e-05	95	90	5	int:SCN2B
Interaction	CDC42 interactions	SEPTIN8 THADA RAP1GDS1 DSP MYO9B ESR1 AGR2 DIAPH1 MCF2 SEPTIN11 PSMD11 SCFD1 EDC4 ZW10 SEPTIN10 IFI16 SEPTIN6	6.78e-05	1323	90	17	int:CDC42
Interaction	SASS6 interactions	BICD2 ERC1 N4BP2 SYCE3 BICD1 NIN	7.91e-05	159	90	6	int:SASS6
Interaction	AP1B1 interactions	DSP ESR1 AGR2 ATM IFI16 USP48 INPP4B	9.29e-05	237	90	7	int:AP1B1
Interaction	KRT18 interactions	BICD2 KNTC1 DSP CEP72 ERC1 N4BP2 ESR1 SMCHD1 NIN	1.06e-04	419	90	9	int:KRT18
Interaction	CENPE interactions	BICD2 CENPH SYCE3 BICD1 NIN	1.13e-04	106	90	5	int:CENPE
Interaction	LRCH3 interactions	SEPTIN8 ESR1 SEPTIN11 SEPTIN10 IFI16	1.23e-04	108	90	5	int:LRCH3
Interaction	PDLIM3 interactions	BICD2 AGR2 BICD1	1.63e-04	24	90	3	int:PDLIM3
Interaction	RAB6B interactions	BICD2 BMPR1B RAP1GDS1 ERC1 ESR1	1.66e-04	115	90	5	int:RAB6B
Interaction	C3orf18 interactions	KNTC1 THADA MTOR ZW10 STAG2	1.66e-04	115	90	5	int:C3orf18
Interaction	ZSCAN12 interactions	BICD2 DSP CENPH PGK2	1.70e-04	62	90	4	int:ZSCAN12
Interaction	SIPA1L3 interactions	BICD2 ESR1 IFI16 BICD1 NIN	1.87e-04	118	90	5	int:SIPA1L3
Interaction	ERC1 interactions	BICD2 ERC1 AGR2 SEPTIN10 BICD1 NIN	1.92e-04	187	90	6	int:ERC1
Interaction	CD83 interactions	THADA MROH1 MTOR STAG2	2.17e-04	66	90	4	int:CD83
Interaction	TAB3 interactions	BICD2 ESR1 IFI16 BICD1	2.17e-04	66	90	4	int:TAB3
Interaction	CEP192 interactions	BICD2 EIF4ENIF1 DIAPH1 SEPTIN10 BICD1 NIN	2.22e-04	192	90	6	int:CEP192
Interaction	ACTR1A interactions	BICD2 ESR1 AGR2 SCFD1 ZW10 USP48 NIN	2.27e-04	274	90	7	int:ACTR1A
Interaction	MLNR interactions	KNTC1 THADA ATM STAG2	2.43e-04	68	90	4	int:MLNR
Interaction	CKAP2 interactions	ESR1 AGR2 SEPTIN10 PGK1 NIN	2.54e-04	126	90	5	int:CKAP2
Interaction	STX16 interactions	ESR1 AGR2 SCFD1 ZW10	2.58e-04	69	90	4	int:STX16
Interaction	SMAD7 interactions	USP26 BMPR1B EIF4ENIF1 WWP1 ATM	2.63e-04	127	90	5	int:SMAD7
Interaction	COMTD1 interactions	KNTC1 THADA MTOR ESR1 ZW10 STAG2	2.76e-04	200	90	6	int:COMTD1
Interaction	CENPA interactions	MED15 CENPH SMCHD1 DIAPH1 USP48 PGK1 STAG2 PRDM2	2.84e-04	377	90	8	int:CENPA
Interaction	LATS2 interactions	CCNE1 PALS1 WWC2 EIF4ENIF1 CEP72 ERC1 NIN	3.14e-04	289	90	7	int:LATS2
Interaction	LRRC31 interactions	KNTC1 DSP MYO9B MTOR SMCHD1 ANKRD30A	3.15e-04	205	90	6	int:LRRC31
Interaction	MUCL1 interactions	SEPTIN8 CEP72 MTHFD2L	3.20e-04	30	90	3	int:MUCL1
Interaction	NDUFB2 interactions	MTOR AGR2 PGK1	3.20e-04	30	90	3	int:NDUFB2
Interaction	CLASP1 interactions	EIF4ENIF1 CENPH ESR1 ZW10 NIN	3.86e-04	138	90	5	int:CLASP1
Interaction	VSIG2 interactions	THADA MTOR STAG2	3.89e-04	32	90	3	int:VSIG2
Interaction	G6PD interactions	DSP ESR1 AGR2 DMD SHOC2 USP48	3.96e-04	214	90	6	int:G6PD
Interaction	ALDOC interactions	AGR2 SHOC2 USP48 PGK1 PGK2	4.12e-04	140	90	5	int:ALDOC
Interaction	C2CD3 interactions	BICD2 BICD1 NIN	4.66e-04	34	90	3	int:C2CD3
Interaction	SNW1 interactions	BICD2 TSNAXIP1 DSP ESR1 SMCHD1 DIAPH1 PSMD11 ATM SHOC2 USP48 NIN	4.88e-04	747	90	11	int:SNW1
Interaction	NDC80 interactions	BICD2 CEP72 ERC1 CENPH ESR1 ZW10 NIN	4.97e-04	312	90	7	int:NDC80
Interaction	KIF7 interactions	BICD2 CEP72 SEPTIN10 BICD1 NIN	4.99e-04	146	90	5	int:KIF7
Interaction	FPR1 interactions	KNTC1 THADA MTOR ATM ZW10	5.15e-04	147	90	5	int:FPR1
Interaction	CEP170B interactions	BICD2 ESR1 BICD1 NIN	5.22e-04	83	90	4	int:CEP170B
Interaction	SH3KBP1 interactions	SEPTIN8 PALS1 BMPR1B ERC1 SEPTIN11 SEPTIN10 SEPTIN6	5.26e-04	315	90	7	int:SH3KBP1
Interaction	ANKRD30A interactions	ANKRD30A ANKRD30B	5.43e-04	8	90	2	int:ANKRD30A
Interaction	ABCA4 interactions	ABCA13 USP48	5.43e-04	8	90	2	int:ABCA4
Interaction	OCIAD1 interactions	BICD2 KNTC1 THADA SYCE3 ATM EDC4 ZW10 STAG2	5.72e-04	419	90	8	int:OCIAD1
Interaction	CITED1 interactions	MYO9B ESR1 STAG2	6.00e-04	37	90	3	int:CITED1
GeneFamily	Septins	SEPTIN8 SEPTIN14 SEPTIN11 SEPTIN10 SEPTIN6	3.00e-10	13	56	5	732
GeneFamily	C2 and WW domain containing	WWC2 WWP1	5.63e-05	4	56	2	838
Coexpression	ONKEN_UVEAL_MELANOMA_UP	MED15 BICD2 RAP1GDS1 AUH TBC1D1 SMCHD1 WWP1 ATM SNX16 SEPTIN10 IFI16 USP48 THUMPD2 INPP4B	4.94e-07	790	90	14	M12490
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	KNTC1 KIF18A CENPH SMCHD1 WWP1 ATM SNX16 IFI16 USP48 STAG2 KRIT1 NIN	2.52e-06	656	90	12	M18979
Coexpression	SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP	SEPTIN8 ESR1 AGR2 LRP1B INPP4B	2.37e-05	99	90	5	M3238
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	AUH WWP1 PSMD11 SCFD1 SEPTIN10 SHOC2 IFI16 PGK1 SEPTIN6 KRIT1	2.55e-05	568	90	10	M4023
Coexpression	GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_DN	KNTC1 N4BP2 TBC1D1 CENPH LYST SEPTIN6	2.70e-05	170	90	6	M6762
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	IBTK AUH MYO9B ERC1 SMCHD1 WWP1 DMD SHOC2 STAG2 KRIT1 FILIP1L BICD1	3.61e-05	856	90	12	M4500
Coexpression	HUTTMANN_B_CLL_POOR_SURVIVAL_UP	MED15 MYO9B TBC1D1 DIAPH1 CASP10 DMD SEPTIN10	5.65e-05	284	90	7	M19993
Coexpression	GSE17721_POLYIC_VS_CPG_0.5H_BMDC_DN	BICD2 KIF18A PALS1 TBC1D1 LYST STAG2	6.69e-05	200	90	6	M3933
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	CCNE1 USP26 KNTC1 KIF18A DSP CEP72 MTOR CENPH CCDC150 SPO11 ATM SNX16 LYST MADD	5.79e-06	820	87	14	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	CCNE1 USP26 KNTC1 KIF18A THADA DSP MTOR CENPH AP3B2 DIAPH1 CCDC150 SPO11 ATM	2.89e-05	822	87	13	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCNE1 KNTC1 KIF18A PHF23 CENPH TRAIP	1.07e-06	165	90	6	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBED6 SMCHD1 DIAPH1 LYST STAG2 FILIP1L	1.67e-06	178	90	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMCHD1 DIAPH1 LYST STAG2 FILIP1L NIN	1.89e-06	182	90	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMCHD1 DIAPH1 SEPTIN11 LYST STAG2 FILIP1L	2.02e-06	184	90	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KNTC1 ESR1 CASP10 ATM USP48 BICD1	2.08e-06	185	90	6	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMCHD1 DIAPH1 LYST STAG2 FILIP1L NIN	2.08e-06	185	90	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX2 DSP CEP72 N4BP2 TRAIP SHOC2	2.29e-06	188	90	6	40ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX2 DSP CEP72 N4BP2 TRAIP SHOC2	2.29e-06	188	90	6	ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 BMPR1B DSP ABCA13 SPAG16	1.39e-05	151	90	5	8216462e723fec2797387929dde095370947e10a
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 KIF18A IBTK CEP72 INPP4B	2.20e-05	166	90	5	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	ASK454-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP47 CASP10 ATM PRKG2 CCDC65	2.46e-05	170	90	5	84705434234bf2fbb5256bd5a1f6ab54c01c5a51
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC14L3 CCNE1 CENPH TRAIP INPP4B	3.24e-05	180	90	5	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B ERC1 TLN2 SPAG16 BICD1	3.24e-05	180	90	5	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CUX2 AP3B2 MAPK10 SMCO2 BICD1	3.32e-05	181	90	5	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SMCHD1 ATM PRDM2 BICD1 NIN	3.32e-05	181	90	5	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	KNTC1 KIF18A CENPH AGR2 USP48	3.50e-05	183	90	5	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	nucseq-Immune-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SMCHD1 ATM USP48 PRDM2 BICD1	3.59e-05	184	90	5	911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SMCHD1 ATM USP48 PRDM2 BICD1	3.59e-05	184	90	5	942b58ae7172bb5f97e55b032db9329d161854af
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B ERC1 TLN2 SPAG16 BICD1	3.69e-05	185	90	5	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PALS1 DSP ZBED6 ESR1 DMD	3.69e-05	185	90	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	E15.5-Epithelial-airway_epithelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SEC14L3 BMPR1B DSP AGR2 DIAPH1	3.78e-05	186	90	5	bb2c7af3b1d8478c49a8626dbfd6c92c5e7adc4a
ToppCell	E15.5-Epithelial-airway_epithelial_cell-club_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SEC14L3 BMPR1B DSP AGR2 DIAPH1	3.78e-05	186	90	5	86c809b99088d3d6c8f87785797c4beefdcddbe7
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	SMCHD1 ATM IFI16 INPP4B SEPTIN6	3.88e-05	187	90	5	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP WWP1 DIAPH1 STAG2 FILIP1L	4.29e-05	191	90	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 TSNAXIP1 AGR2 SPAG16 CCDC65	4.29e-05	191	90	5	e8d56e9f43943e9cc4dce83f2c234f19c2dd487d
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 TSNAXIP1 AGR2 SPAG16 CCDC65	4.29e-05	191	90	5	52e8d7dfaf1ebb6df8bf3a1f4546af59faa67657
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP WWP1 DIAPH1 STAG2 FILIP1L	4.29e-05	191	90	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP WWP1 DIAPH1 STAG2 FILIP1L	4.29e-05	191	90	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B ERC1 MTHFD2L SEPTIN10 BICD1	4.40e-05	192	90	5	2510f22197502f60fd266b7f42eff040f25b8ae7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B ERC1 MTHFD2L SEPTIN10 BICD1	4.40e-05	192	90	5	e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO9B SMCHD1 AP3B2 SHOC2 PRDM2	4.51e-05	193	90	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 ABCA13 AGR2 SPAG16 MAPK10	4.62e-05	194	90	5	958e648138676d46698090b4046cb484083ae449
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ERC1 ZBED6 N4BP2 SMCHD1 ATM	4.74e-05	195	90	5	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 PALS1 WWC2 DSP WWP1	4.85e-05	196	90	5	9790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 PALS1 WWC2 DSP WWP1	4.85e-05	196	90	5	b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	UNC45B TBC1D1 DMD INPP4B FILIP1L	4.85e-05	196	90	5	1d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CFAP47 BMPR1B AGR2 SPAG16 MAPK10	4.85e-05	196	90	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	UNC45B TBC1D1 DMD INPP4B FILIP1L	4.85e-05	196	90	5	aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEC14L3 CFAP47 ABCA13 SPAG16 CCDC65	4.97e-05	197	90	5	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEC14L3 CFAP47 ABCA13 SPAG16 CCDC65	4.97e-05	197	90	5	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEC14L3 CFAP47 ABCA13 SPAG16 CCDC65	4.97e-05	197	90	5	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEC14L3 CFAP47 ABCA13 SPAG16 CCDC65	4.97e-05	197	90	5	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	UNC45B ESR1 TRAIP MCF2 EDC4	5.09e-05	198	90	5	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	medial-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.09e-05	198	90	5	64a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCell	medial-Hematologic-Proliferating_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.09e-05	198	90	5	fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCell	medial-Hematologic-Proliferating_Macrophage\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.09e-05	198	90	5	da6963184c32761c896a9b91a5321ad84b583736
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CFAP47 TSNAXIP1 SPAG16 MAPK10 CCDC65	5.34e-05	200	90	5	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	mild-T/NK_proliferative\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.34e-05	200	90	5	25b4a1a33348e274bd4457efc0d6faa5421c3d31
ToppCell	distal-Hematologic-Proliferating_Macrophage-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.34e-05	200	90	5	9c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.34e-05	200	90	5	04bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.34e-05	200	90	5	f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SMCHD1 IFI16 LYST INPP4B SEPTIN6	5.34e-05	200	90	5	510d84bf7a4621b079e5a7330d25e04508c84a49
ToppCell	distal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCNE1 KNTC1 KIF18A CENPH TRAIP	5.34e-05	200	90	5	1b65c97e8123d0572d31525d6a10bc7f16857959
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	TLN2 IFI16 LRP1B LYST FILIP1L	5.34e-05	200	90	5	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KNTC1 KIF18A CENPH TRAIP CCDC150	5.34e-05	200	90	5	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Substantia_nigra-Macroglia-CSF_related\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TSNAXIP1 CCDC150 ACSBG2 SPAG16	1.67e-04	136	90	4	47663c5d81c766a333207a44fc5b58b07309ee76
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TSNAXIP1 CCDC150 ACSBG2 SPAG16	1.67e-04	136	90	4	6d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TSNAXIP1 CCDC150 ACSBG2 SPAG16	1.67e-04	136	90	4	fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TSNAXIP1 CCDC150 ACSBG2 SPAG16	1.67e-04	136	90	4	3f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TSNAXIP1 CCDC150 ACSBG2 SPAG16	1.67e-04	136	90	4	67d736096d6b6ddb4722809557f5e987063b8d23
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEC14L3 KNTC1 CUX2 PRKG2	1.76e-04	138	90	4	b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1B CMA1 INPP4B SEPTIN6	1.76e-04	138	90	4	10c263c58b83a018791f77098f18927d904cb13b
ToppCell	LPS-IL1RA-Hematopoietic_Mast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1B CMA1 INPP4B SEPTIN6	1.97e-04	142	90	4	f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1B CMA1 INPP4B SEPTIN6	1.97e-04	142	90	4	2a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SEC14L3 ABCA13 ESR1 EDC4	2.02e-04	143	90	4	8f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1B CMA1 INPP4B SEPTIN6	2.43e-04	150	90	4	7290e9a812b1b2f919e67ccde0acf52687ab138f
ToppCell	TCGA-Breast\|World / Sample_Type by Project: Shred V9	ESR1 WWP1 ANKRD30A ANKRD30B	2.43e-04	150	90	4	08686ba1acac5c58667bf62e2af84c691d6bbdfb
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CUX2 SEPTIN14 ANKRD30A LRP1B	2.43e-04	150	90	4	0205318a870e091add66ee4305747dda9f51510d
ToppCell	LPS_only-Hematopoietic_Mast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1B CMA1 INPP4B SEPTIN6	2.43e-04	150	90	4	2c5078a1f769ba8153dee756b53d28eb7b434a96
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSNAXIP1 AGR2 CCDC150 SPAG16	2.49e-04	151	90	4	e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEC14L3 ABCA13 SPO11 BICD1	2.49e-04	151	90	4	16fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSNAXIP1 AGR2 CCDC150 SPAG16	2.49e-04	151	90	4	633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_large-bowel / Manually curated celltypes from each tissue	UNC45B SMCHD1 AGR2 INPP4B	2.55e-04	152	90	4	95944864ce7539ff8de028f5700694931338f3ff
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	CFAP47 BMPR1B ABCA13 INPP4B	2.82e-04	156	90	4	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OR2T2 ATM BICD1 NIN	2.82e-04	156	90	4	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	IFI16 CCDC65 THUMPD2 INPP4B	2.89e-04	157	90	4	2c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNE1 CENPH INPP4B SEPTIN6	3.03e-04	159	90	4	a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCell	Ciliated_cells-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SEC14L3 BMPR1B ABCA13 CCDC65	3.03e-04	159	90	4	0c65ae6140abd48c79b04758a6217709ddd15385
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	CUX2 LPO MCF2 MADD	3.18e-04	161	90	4	5f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell	Club_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	BMPR1B DSP AGR2 LRP1B	3.18e-04	161	90	4	342f5c61d37df61b35c18f5d258043a8f5cef629
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESR1 DMD INPP4B FILIP1L	3.25e-04	162	90	4	68c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MTHFD2L SEPTIN10 LRP1B LYST	3.25e-04	162	90	4	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESR1 DMD INPP4B FILIP1L	3.25e-04	162	90	4	735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B TBC1D1 ANKRD30A INPP4B	3.49e-04	165	90	4	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPH TRAIP CMA1 BICD1	3.57e-04	166	90	4	21ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	SMCHD1 ATM SEPTIN6 PRDM2	3.73e-04	168	90	4	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ESR1 SMCHD1 SEPTIN14 CASP10	3.73e-04	168	90	4	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	BAL-Control-cDC_6\|Control / Compartment, Disease Groups and Clusters	TSNAXIP1 KIF18A TLN2 THUMPD2	3.73e-04	168	90	4	65ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 TSNAXIP1 SPAG16 CCDC65	3.73e-04	168	90	4	fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 TSNAXIP1 SPAG16 CCDC65	3.73e-04	168	90	4	7edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 KIF18A CEP72 TRAIP	3.82e-04	169	90	4	02fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 KIF18A CENPH CCDC150	3.82e-04	169	90	4	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 ABCA13 AGR2 PGK1	3.82e-04	169	90	4	08ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B TBC1D1 ESR1 ANKRD30A	3.82e-04	169	90	4	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 ABCA13 AGR2 PGK1	3.82e-04	169	90	4	e5abd41db1e6724ad900e37658fa063b8e522908
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR1B ERC1 MAPK10 BICD1	3.90e-04	170	90	4	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP ANKRD30B PRKG2 PNPLA7	3.90e-04	170	90	4	985c2d5962100fab0d95bee39f382ccbe799331e
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC14L3 CFAP47 TSNAXIP1 CCDC65	3.99e-04	171	90	4	4f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNE1 KIF18A CENPH TRAIP	4.08e-04	172	90	4	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCNE1 CENPH TRAIP SEPTIN6	4.08e-04	172	90	4	7c238a7375341d4647ba7274d93fddfb6fae7ce4
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A	BICD2 WWC2 ERC1 ESR1 DIAPH1 PRDM2 BICD1	8.83e-06	185	90	7	1673_DN
Drug	Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A	AUH ESR1 TRAIP SEPTIN11 TLN2 PSMD11 ATM	1.24e-05	195	90	7	1523_DN
Drug	Ant-dATP	PGK1 PGK2 KRIT1	1.28e-05	12	90	3	CID000131323
Drug	Lisinopril [83915-83-7]; Up 200; 9uM; HL60; HT_HG-U133A	SEPTIN8 MYO9B ESR1 CASP10 LRRC8B SEPTIN6 BICD1	1.33e-05	197	90	7	2371_UP
Drug	Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SMCHD1 SEPTIN11 SNX16 SHOC2 USP48 KRIT1 BICD1	1.37e-05	198	90	7	4837_DN
Drug	Azathioprine [446-86-6]; Up 200; 14.4uM; PC3; HG-U133A	THADA MYO9B SMCHD1 MTHFD2L TLN2 PSMD11 KRIT1	1.37e-05	198	90	7	1945_UP
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A	MYO9B MTOR ESR1 ATM LYST PRDM2 FILIP1L	1.37e-05	198	90	7	5259_DN
Drug	Niridazole [61-57-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	TSNAXIP1 SEPTIN11 IFI16 USP48 MADD FILIP1L BICD1	1.37e-05	198	90	7	4621_DN
Drug	Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; PC3; HG-U133A	SMCHD1 WWP1 SEPTIN11 LYST STAG2 MADD KRIT1	1.37e-05	198	90	7	1902_UP
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A_EA	CCNE1 WWC2 CEP72 ERC1 ESR1 SEPTIN11 USP48	1.42e-05	199	90	7	997_DN
Drug	rapamycin; Down 200; 0.1uM; ssMCF7; HG-U133A	BICD2 SEPTIN8 WWC2 MYO9B CEP72 TLN2 BICD1	1.42e-05	199	90	7	402_DN
Drug	6-fluorocholesterol	ATM LYST	1.55e-05	2	90	2	CID000135206
Drug	25-fluorocholesterol	ATM LYST	1.55e-05	2	90	2	CID006454807
Drug	4-Arsono-2-hydroxybutanoic acid	PGK1 PGK2	1.55e-05	2	90	2	CID000135804
Drug	ZM447439	MTOR AP3B2 ZW10	3.90e-05	17	90	3	CID009914412
Drug	AC1O5U9L	PGK1 PGK2	4.62e-05	3	90	2	CID006440811
Drug	2-nitroestradiol	ESR1 LPO	4.62e-05	3	90	2	CID000233493
Drug	Dirian	PGK1 PGK2	4.62e-05	3	90	2	CID003034337
Drug	AC1NDNJY	PGK1 PGK2	4.62e-05	3	90	2	CID004578722
Drug	4-nitroestradiol	ESR1 LPO	9.22e-05	4	90	2	CID000233494
Drug	repin	PGK1 PGK2	9.22e-05	4	90	2	CID000091567
Drug	ERA-923	MTOR ESR1	9.22e-05	4	90	2	CID006433099
Drug	Flavanones	CCNE1 MTOR ATM	1.14e-04	24	90	3	ctd:D044950
Drug	Glipizide [29094-61-9]; Down 200; 9uM; PC3; HG-U133A	BICD2 KIF18A IBTK SMCHD1 WWP1 STAG2	1.18e-04	193	90	6	1926_DN
Drug	Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; MCF7; HT_HG-U133A	MYO9B ESR1 TRAIP SEPTIN11 ATM ZW10	1.18e-04	193	90	6	4113_DN
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A	ESR1 TRAIP PSMD11 ATM MAPK10 BICD1	1.18e-04	193	90	6	3627_DN
Drug	Trifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ERC1 ESR1 MTHFD2L ATM LYST FILIP1L	1.18e-04	193	90	6	7176_UP
Drug	Amphotericin B [1397-89-3]; Down 200; 4.4uM; MCF7; HT_HG-U133A	KIF18A MYO9B SEPTIN11 TLN2 EDC4 LYST	1.22e-04	194	90	6	3303_DN
Drug	Oxybutynin chloride [1508-65-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A	WWC2 MTOR TLN2 USP48 LYST MADD	1.22e-04	194	90	6	3168_DN
Drug	Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	BICD2 AUH CEP72 SMCHD1 ATM SNX16	1.22e-04	194	90	6	4772_DN
Drug	5666823; Down 200; 100uM; MCF7; HG-U133A	CCNE1 BICD2 MYO9B ESR1 TLN2 BICD1	1.25e-04	195	90	6	609_DN
Drug	Thiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A	MYO9B ESR1 SEPTIN11 PSMD11 ATM KRIT1	1.25e-04	195	90	6	2875_DN
Drug	Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	CCNE1 ESR1 SMCHD1 DIAPH1 SEPTIN11 PRDM2	1.25e-04	195	90	6	4961_DN
Drug	Scoulerine [6451-73-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	TLN2 LRRC8B PRKG2 IFI16 LYST BICD1	1.29e-04	196	90	6	5111_DN
Drug	Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A	BICD2 KIF18A WWP1 CASP10 ATM SEPTIN6	1.29e-04	196	90	6	1841_DN
Drug	Epiandrosterone [481-29-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A	BICD2 ESR1 DIAPH1 ZW10 LYST BICD1	1.29e-04	196	90	6	3306_DN
Drug	(+/-)-blebbistatin; Down 200; 17uM; MCF7; HT_HG-U133A_EA	MED15 WWC2 CEP72 ESR1 SEPTIN11 PRDM2	1.29e-04	196	90	6	837_DN
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A	MYO9B ESR1 DIAPH1 TLN2 PSMD11 BICD1	1.29e-04	196	90	6	1679_DN
Drug	Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; MCF7; HT_HG-U133A	MED15 ESR1 TLN2 PSMD11 ATM LYST	1.29e-04	196	90	6	6263_DN
Drug	AH6809; Up 200; 1uM; PC3; HT_HG-U133A	SEPTIN8 ESR1 LRRC8B SEPTIN6 MADD BICD1	1.32e-04	197	90	6	7049_UP
Drug	Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A	ESR1 SMCHD1 TRAIP ZW10 USP48 BICD1	1.32e-04	197	90	6	2812_DN
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A	RAP1GDS1 MYO9B TRAIP SEPTIN11 PSMD11 KRIT1	1.32e-04	197	90	6	4966_DN
Drug	Thiorphan [76721-89-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A	WWC2 ESR1 DIAPH1 ATM ZW10 BICD1	1.32e-04	197	90	6	2752_DN
Drug	Gliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	BICD2 MYO9B ESR1 SEPTIN11 PSMD11 KRIT1	1.32e-04	197	90	6	2870_DN
Drug	Hesperetin [520-33-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A	RAP1GDS1 SMCHD1 LRRC8B ATM USP48 KRIT1	1.32e-04	197	90	6	5350_DN
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A	TBC1D1 ESR1 DIAPH1 ATM ZW10 PRDM2	1.32e-04	197	90	6	1674_DN
Drug	Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SEPTIN8 MTOR TRAIP SEPTIN11 USP48 MADD	1.36e-04	198	90	6	7177_DN
Drug	Roxithromycin [80214-83-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A	CEP72 ERC1 SEPTIN11 SNX16 KRIT1 BICD1	1.40e-04	199	90	6	4778_DN
Drug	Mifepristone [84371-65-3]; Up 200; 9.4uM; HL60; HG-U133A	IBTK THADA TRAIP IFI16 KRIT1 BICD1	1.40e-04	199	90	6	1569_UP
Drug	Benperidol [2062-84-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A	MED15 KIF18A ESR1 SMCHD1 TRAIP TLN2	1.44e-04	200	90	6	2836_DN
Drug	Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; HL60; HT_HG-U133A	SEPTIN8 SEPTIN11 TLN2 ZW10 MADD BICD1	1.44e-04	200	90	6	2963_UP
Drug	totarol	DSP LPO	1.53e-04	5	90	2	CID000092783
Drug	[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[4-(3-oxobutyl)phenoxy]oxan-3-yl] 3,4,5-trihydroxybenzoate	ESR1 LYST	1.53e-04	5	90	2	CID010390322
Drug	clorsulon	PGK1 PGK2	1.53e-04	5	90	2	CID000043231
Disease	Bladder Neoplasm	CCNE1 MTOR ESR1 ATM STAG2 INPP4B PRDM2	1.98e-07	140	87	7	C0005695
Disease	Malignant neoplasm of urinary bladder	CCNE1 MTOR ESR1 ATM STAG2 INPP4B PRDM2	2.08e-07	141	87	7	C0005684
Disease	spinal muscular atrophy with lower extremity predominant 2A (implicated_via_orthology)	BICD2 BICD1	8.59e-06	2	87	2	DOID:0070349 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of bladder	MTOR ATM STAG2	1.10e-05	15	87	3	C0496930
Disease	Benign neoplasm of bladder	MTOR ATM STAG2	1.10e-05	15	87	3	C0154017
Disease	Carcinoma in situ of bladder	MTOR ATM STAG2	1.10e-05	15	87	3	C0154091
Disease	body weight	CCNE1 KNTC1 TNNI3K CUX2 MTOR TBC1D1 ESR1 SMCHD1 TLN2 PRKG2 DMD LRP1B PGK1 BICD1	1.84e-05	1261	87	14	EFO_0004338
Disease	Carcinoma of bladder	MTOR ATM STAG2	1.96e-05	18	87	3	C0699885
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	MTOR ATM LRP1B PGK1 INPP4B	7.87e-05	148	87	5	C0279702
Disease	free androgen index	KIF18A THADA CUX2 ESR1 SMCHD1 TRAIP USP48	1.22e-04	374	87	7	EFO_0007005
Disease	Lennox-Gastaut syndrome	CUX2 MAPK10	1.28e-04	6	87	2	C0238111
Disease	Liver carcinoma	CCNE1 KIF18A MTOR ESR1 TRAIP ATM PGK1 INPP4B	1.28e-04	507	87	8	C2239176
Disease	infertility (implicated_via_orthology)	ESR1 ATM	1.79e-04	7	87	2	DOID:5223 (implicated_via_orthology)
Disease	orofacial cleft	THADA TLN2 FILIP1L	1.79e-04	37	87	3	MONDO_0000358
Disease	breast carcinoma	CCNE1 CUX2 MYO9B ZBED6 ESR1 ANKRD30A DMD MAPK10 MADD KRIT1 FILIP1L	2.01e-04	1019	87	11	EFO_0000305
Disease	Malignant neoplasm of breast	CCNE1 MTOR UNC45B N4BP2 ESR1 AGR2 ANKRD30A ATM DMD INPP4B NLRP8	3.15e-04	1074	87	11	C0006142
Disease	Papillary Renal Cell Carcinoma	MTOR LRP1B PGK1 INPP4B	5.69e-04	128	87	4	C1306837
Disease	Malignant Neoplasms	CCNE1 MTOR ESR1 ATM	5.69e-04	128	87	4	C0006826
Disease	Renal Cell Carcinoma	MTOR LRP1B PGK1 INPP4B	5.69e-04	128	87	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	MTOR LRP1B PGK1 INPP4B	5.69e-04	128	87	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	MTOR LRP1B PGK1 INPP4B	5.69e-04	128	87	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	MTOR LRP1B PGK1 INPP4B	5.69e-04	128	87	4	C1266044
Disease	leukemia	ESR1 ATM STAG2	5.81e-04	55	87	3	C0023418
Disease	body surface area	CCNE1 KNTC1 WWC2 MYO9B MTOR ESR1 SMCHD1 PRKG2	6.28e-04	643	87	8	EFO_0022196
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	MTOR ATM	1.00e-03	16	87	2	C0334634
Disease	gait measurement	CCNE1 KNTC1 TRAIP MAPK10	1.03e-03	150	87	4	EFO_0007680
Disease	Benign neoplasm of stomach	CASP10 ATM	1.14e-03	17	87	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	CASP10 ATM	1.14e-03	17	87	2	C0496905
Disease	Carcinoma in situ of stomach	CASP10 ATM	1.14e-03	17	87	2	C0154060
Disease	cancer (implicated_via_orthology)	CUX2 MTOR ATM PGK1 PGK2	1.20e-03	268	87	5	DOID:162 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	CCNE1 WWC2 CUX2 MTOR SEPTIN14 SEPTIN10 SHOC2 INPP4B MADD	1.39e-03	904	87	9	EFO_0004736
Disease	Usual Interstitial Pneumonia	DSP ESR1	1.42e-03	19	87	2	C4721509
Disease	Hamman-Rich Disease	DSP ESR1	1.42e-03	19	87	2	C4721508
Disease	puberty, height growth measurement	TNNI3K PRKG2	1.42e-03	19	87	2	EFO_0001382, EFO_0005201
Disease	Cleft palate, cleft lip	THADA CUX2 ABCA13 TLN2 FILIP1L	1.43e-03	279	87	5	EFO_0003959, HP_0000175
Disease	Familial Idiopathic Pulmonary Fibrosis	DSP ESR1	1.58e-03	20	87	2	C4721952
Disease	BREAST CANCER	ESR1 ATM	1.74e-03	21	87	2	114480
Disease	Idiopathic Pulmonary Fibrosis	DSP ESR1	1.74e-03	21	87	2	C1800706
Disease	Stomach Carcinoma	CASP10 ATM	1.74e-03	21	87	2	C0699791
Disease	breast cancer, COVID-19	CUX2 ESR1	1.91e-03	22	87	2	MONDO_0007254, MONDO_0100096
Disease	Alveolitis, Fibrosing	DSP MTOR CMA1	1.92e-03	83	87	3	C4721507
Disease	Pulmonary Fibrosis	DSP MTOR CMA1	2.05e-03	85	87	3	C0034069
Disease	Left Ventricular Hypertrophy	MTOR CMA1	2.47e-03	25	87	2	C0149721
Disease	atopic dermatitis (is_implicated_in)	CMA1 SHOC2	2.67e-03	26	87	2	DOID:3310 (is_implicated_in)
Disease	Malignant tumor of breast	ESR1 ATM	2.88e-03	27	87	2	cv:C0006142
Disease	Breast neoplasm	ESR1 ATM	2.88e-03	27	87	2	cv:C1458155
Disease	Familial cancer of breast	ESR1 ATM	2.88e-03	27	87	2	cv:C0346153
Disease	Adenocarcinoma of large intestine	TNNI3K ATM PRKG2	2.90e-03	96	87	3	C1319315

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKEMLLLNLKKAISA	USP26	356	Q9BXU7
VGDKLKFLSMLLTLK	ACSBG2	546	Q5FVE4
DTALLLDNMKKALKL	AGR2	156	O95994
LTAENTMLTSKLKEK	ANKRD30B	1151	Q9BXX2
ALMEEILKLKSLLST	BICD2	671	Q8TD16
MEEILKLKSLLSTKR	BICD1	671	Q96G01
KMAKTPLSDEKQLLL	CCDC65	6	Q8IXS2
SLDLLDKARAKKAML	CCNE1	366	P24864
LQMTLKLKEESLTKR	ANKRD30A	1146	Q9BXX3
LIAENTMLTSKLKEK	ANKRD30A	1171	Q9BXX3
ATSMDSIVKLLKLVK	ABCA13	2516	Q86UQ4
ENSRLKSLLLSMKKE	CEP72	526	Q9P209
MLSSLQKLAVLKADL	DMD	596	P11532
KLRDTKSTDQKMTLL	DIAPH1	1006	O60610
KTELSILKAMKLASS	CUX2	366	O14529
LKSTTLDAKSMLKLA	BMPR1B	291	O00238
DLKEMLDTNKDSLKL	AP3B2	41	Q13367
MSLSKKLTLDKLDVR	PGK2	1	P07205
KLLEMLQSKGLSAKA	ERC1	311	Q8IUD2
MKENISKLLKSKNLT	EDC4	1081	Q6P2E9
KMLQDLLSKDKTISF	OR2T2	81	Q6IF00
ELTKATALTIMDKKL	LRP1B	1776	Q9NZR2
SLELKKHLKQALASM	MADD	421	Q8WXG6
KLKASQARDLLSKML	MAPK10	326	P53779
MISALCKNKTLKSLD	NLRP8	916	Q86W28
NLIKMLSKAVDALKS	AUH	106	Q13825
ALTEKLTLKNAAMLL	IBTK	866	Q9P2D0
LKLEMLLKENELKSF	KIF18A	441	Q8NI77
DSLKNSLKMLSEKTE	INPP4B	441	O15327
LMIKRSKKNSLALSL	ESR1	296	P03372
LEELNTVLKSKMLAK	LPO	581	P22079
KDLSKMKSLLDILTD	MED15	561	Q96RN5
NLKLIALTASANKKM	KNTC1	316	P50748
SALEIKSKMLALEKA	KRIT1	211	O00522
MSLSNKLTLDKLDVK	PGK1	1	P00558
KMLQDLLSKDKTISF	OR2T35	81	Q8NGX2
MKKLASTLLDAITDK	MROH1	6	Q8NDA8
LSKALSLEMIQLKEK	PRKG2	426	Q13237
KKDLLTLMKLEDSSL	PNPLA7	456	Q6ZV29
LKKMVNLKSLELISC	LRRC8B	581	Q6P9F7
KQELDLNSSMRLKKL	PALS1	76	Q8N3R9
SLALSILKQMIKKLD	ATM	2306	Q13315
LRESLEKSASAMLLK	CCDC150	226	Q8NCX0
MRLSTALKKNLEKIS	CENPH	106	Q9H3R5
LKEDLTKLKTLTVMF	FILIP1L	486	Q4L180
NDLNLKKSLLATMKT	DSP	816	P15924
FLSEMLKSLEDLKLK	DSP	1016	P15924
MDNLSDTLKKLKITA	RAP1GDS1	1	P52306
KRTMKEDLLSLAIKS	LYST	1031	Q99698
KSLLSNDLKLNLKMR	IFI16	26	Q16666
ALLKKALDAMLDLLK	MCF2	656	P10911
LKDMIFLLKDSLPKT	CASP10	131	Q92851
LLFSVTKQDLLKTKM	SEC14L3	111	Q9UDX4
KPQFKLMLTSLDKEL	CFAP47	81	Q6ZTR5
SVELSKMSSNKLKLN	PRDM2	1406	Q13029
LKKDIQDGLLKMLSL	MTOR	531	P42345
DVKILAFDLLMKLSK	THADA	801	Q6YHU6
LTFMDLELKLKDKNT	SMCHD1	526	A6NHR9
SLKSLDLLTMKNLDS	SEPTIN14	171	Q6ZU15
LKSLDLVTMKKLDSK	SEPTIN11	161	Q9NVA2
LRSDLDKAEKLKSLM	NIN	386	Q8N4C6
SQLLRELKKMDDKAL	PSMD11	151	O00231
TVEKDIKNLSKLSML	SHOC2	206	Q9UQ13
SLKSLDLVTMKKLDS	SEPTIN6	161	Q14141
MLQKAKVDLKPLLSS	EIF4ENIF1	401	Q9NRA8
IMLLKLKEKASLTLA	CMA1	111	P23946
TKKDLKQITSHLLDM	UNC45B	271	Q8IWX7
KRSMANLKIELSKLD	WWC2	316	Q6AWC2
KSAQKFSLILKILSM	SPO11	106	Q9Y5K1
SSSTKEDLLRLKKQM	STAG2	751	Q8N3U4
KMLSDLNKDLEKLLE	SYCE3	16	A1L190
TLLKEKMLTSLERDK	SPAG16	236	Q8N0X2
EKLLSSESKLKQAML	TBC1D1	1116	Q86TI0
SDLNMLKKLKSAERL	THUMPD2	56	Q9BTF0
EKIMSKTTLDKSLLD	SCFD1	426	Q8WVM8
SLDLVTMKKLDSKVN	SEPTIN8	166	Q92599
ENTVKSLLKDMLTLK	SMCO2	166	A6NFE2
TLLEKMKLKDSLFDL	PHF23	126	Q9BUL5
LKTLDLLTMKNLDSK	SEPTIN10	186	Q9P0V9
VAMLLKNTLLAAKKI	MTHFD2L	331	Q9H903
SLKLETDTLLSAMLK	ZBED6	746	P86452
IDMENSKKLLAAAKL	TLN2	851	Q9Y4G6
MLSKKLTIKDLESID	WWP1	686	Q9H0M0
SLLKKEKMNLLKLID	TSNAXIP1	146	Q2TAA8
MESLKKLLSEKQLHI	SNX16	251	P57768
KSMTKEKADILLLRA	TNNI3K	436	Q59H18
SKLFMSLLEDTLSKQ	USP48	186	Q86UV5
TKKTQEMKTDLNLLL	TERB1	6	Q8NA31
LKILKSLSMELTIQK	ZW10	156	O43264
SLKKKLTMLQETLNL	TRAIP	266	Q9BWF2
KKLLKTLTASEMLPL	N4BP2	1466	Q86UW6
KNLLDSKSLKLIISM	MYO9B	791	Q13459