Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	axon guidance receptor activity	EPHB3 ROBO1 PALLD	5.10e-05	13	115	3	GO:0008046
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A	6.47e-05	14	115	3	GO:0031402
GeneOntologyMolecularFunction	ATP-dependent activity	SMCHD1 WRNIP1 RNF213 TOP6BL KIF7 CCT8L2 STARD9 ABCC8 AACS HFM1 CCT8L1P DYNC1H1	2.21e-04	614	115	12	GO:0140657
GeneOntologyMolecularFunction	cell-cell adhesion mediator activity	NRCAM MYPN PALLD PLXNB3	4.23e-04	61	115	4	GO:0098632
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN3A	4.39e-04	26	115	3	GO:0005248
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A	4.39e-04	26	115	3	GO:0031420
GeneOntologyBiologicalProcess	neuron recognition	EPHB3 NRCAM MYPN ROBO1 PALLD	2.03e-05	59	116	5	GO:0008038
GeneOntologyCellularComponent	axon initial segment	NRCAM MAP1A SCN1A SCN2A	2.12e-05	29	119	4	GO:0043194
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN3A	1.15e-04	17	119	3	GO:0001518
GeneOntologyCellularComponent	main axon	NRCAM MAP1A SCN1A SCN2A ROBO1	1.56e-04	89	119	5	GO:0044304
GeneOntologyCellularComponent	node of Ranvier	NRCAM SCN1A SCN2A	1.91e-04	20	119	3	GO:0033268
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN3A	5.90e-04	29	119	3	GO:0034706
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A	4.03e-06	6	111	3	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A	4.03e-06	6	111	3	IPR024583
Domain	Na_channel_asu	SCN1A SCN2A SCN3A	2.38e-05	10	111	3	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A	2.38e-05	10	111	3	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A	2.38e-05	10	111	3	PF06512
Domain	IGc2	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD LILRA4	8.09e-05	235	111	8	SM00408
Domain	Ig_sub2	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD LILRA4	8.09e-05	235	111	8	IPR003598
Domain	FN3	EPHB3 EPOR NRCAM INSRR IGDCC4 IL21R ROBO1	1.19e-04	185	111	7	SM00060
Domain	Ig_I-set	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD	1.41e-04	190	111	7	IPR013098
Domain	I-set	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD	1.41e-04	190	111	7	PF07679
Domain	-	EPHB3 EPOR MXRA5 NRCAM INSRR IGDCC4 HMCN1 IL21R MYPN ROBO1 PALLD PLXNB3 LILRA4	1.55e-04	663	111	13	2.60.40.10
Domain	FN3	EPHB3 EPOR NRCAM INSRR IGDCC4 IL21R ROBO1	1.87e-04	199	111	7	PS50853
Domain	CABIT	THEMIS2 GAREM1	2.08e-04	4	111	2	PF12736
Domain	CABIT_dom	THEMIS2 GAREM1	2.08e-04	4	111	2	IPR025946
Domain	FN3_dom	EPHB3 EPOR NRCAM INSRR IGDCC4 IL21R ROBO1	2.52e-04	209	111	7	IPR003961
Domain	Ig-like_fold	EPHB3 EPOR MXRA5 NRCAM INSRR IGDCC4 HMCN1 IL21R MYPN ROBO1 PALLD PLXNB3 LILRA4	2.87e-04	706	111	13	IPR013783
Domain	fn3	EPHB3 EPOR NRCAM INSRR IGDCC4 ROBO1	4.15e-04	162	111	6	PF00041
Domain	SAM_1	EPHB3 SASH1 GAREM1 ANKS1A	7.18e-04	68	111	4	PF00536
Domain	TLV_coat	ERVV-2 ERVV-1	7.21e-04	7	111	2	PF00429
Domain	TLV/ENV_coat_polyprotein	ERVV-2 ERVV-1	9.57e-04	8	111	2	IPR018154
Domain	SAM_DOMAIN	EPHB3 SASH1 GAREM1 ANKS1A	2.48e-03	95	111	4	PS50105
Domain	SAM	EPHB3 SASH1 GAREM1 ANKS1A	2.68e-03	97	111	4	IPR001660
Domain	IG	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD LILRA4	3.65e-03	421	111	8	SM00409
Domain	Ig_sub	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD LILRA4	3.65e-03	421	111	8	IPR003599
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN3A	4.73e-03	57	111	3	IPR027359
Domain	-	SCN1A SCN2A SCN3A	4.73e-03	57	111	3	1.20.120.350
Domain	SAM/pointed	EPHB3 SASH1 GAREM1 ANKS1A	5.24e-03	117	111	4	IPR013761
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	NRCAM SCN1A SCN2A SCN3A	1.98e-05	31	74	4	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	RANGRF SCN1A SCN2A SCN3A	2.25e-05	32	74	4	M27455
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	4.01e-08	3	120	3	12610651
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	4.01e-08	3	120	3	23859570
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	4.01e-08	3	120	3	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	4.01e-08	3	120	3	17544618
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	4.01e-08	3	120	3	14973256
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MAP1A ATG2B PFAS IBTK UBR5 MYPN ROBO1 PALLD ANKS1A	5.05e-08	209	120	9	36779422
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	NEDD4 SCN1A SCN2A SCN3A	9.41e-08	13	120	4	15123669
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A	1.60e-07	4	120	3	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A	1.60e-07	4	120	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A	1.60e-07	4	120	3	29578003
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	1.60e-07	4	120	3	35801810
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	1.60e-07	4	120	3	8974318
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN2A SCN3A	3.99e-07	5	120	3	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN2A SCN3A	3.99e-07	5	120	3	8812438
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	3.99e-07	5	120	3	24337656
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN3A	7.95e-07	6	120	3	23652591
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGDS SASH1 SMCHD1 SANBR SMPD4 IBTK AP5Z1 PAN2 NUP188 ARHGAP20 ANKS1A	2.37e-06	529	120	11	14621295
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN3A	3.31e-06	9	120	3	16382098
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A	3.31e-06	9	120	3	15746173
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A	8.61e-06	12	120	3	8169823
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN3A	8.61e-06	12	120	3	30175250
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	1.18e-05	2	120	2	29649454
Pubmed	SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression.	SENP3 WNT10A	1.18e-05	2	120	2	38273178
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	1.18e-05	2	120	2	20346423
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	1.18e-05	2	120	2	10827969
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	1.18e-05	2	120	2	19694741
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	1.18e-05	2	120	2	11245985
Pubmed	Placenta growth factor induces invasion and activates p70 during rapamycin treatment in trophoblast cells.	PGF UBASH3B	1.18e-05	2	120	2	25271148
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	1.18e-05	2	120	2	1317301
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	1.18e-05	2	120	2	23016767
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	1.18e-05	2	120	2	27153334
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	1.18e-05	2	120	2	33096315
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	1.18e-05	2	120	2	24990319
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	1.18e-05	2	120	2	31439038
Pubmed	Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.	ERVV-2 ERVV-1	1.18e-05	2	120	2	18826608
Pubmed	Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.	ARHGEF19 DVL2	1.18e-05	2	120	2	38714795
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	1.18e-05	2	120	2	26311622
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	1.18e-05	2	120	2	15249644
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	1.18e-05	2	120	2	27690330
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	1.18e-05	2	120	2	21377452
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	1.18e-05	2	120	2	23965409
Pubmed	Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.	ERVV-2 ERVV-1	1.18e-05	2	120	2	23555306
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	1.18e-05	2	120	2	30693367
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	RALGDS SMPD4 IBTK STARD9 SCN3A ARHGAP20	1.59e-05	153	120	6	10718198
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	SCN1A SCN2A SCN3A	1.77e-05	15	120	3	9726281
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN3A	3.53e-05	3	120	2	19284629
Pubmed	Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.	SCN1A SCN2A	3.53e-05	3	120	2	28784306
Pubmed	Febrile infection-related epilepsy syndrome (FIRES) is not caused by SCN1A, POLG, PCDH19 mutations or rare copy number variations.	POLG SCN1A	3.53e-05	3	120	2	23066759
Pubmed	Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.	SCN1A SCN2A	3.53e-05	3	120	2	32185219
Pubmed	Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.	SCN1A SCN2A	3.53e-05	3	120	2	32005694
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A	3.53e-05	3	120	2	33895391
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A	3.53e-05	3	120	2	32845893
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A	3.53e-05	3	120	2	28518218
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	3.53e-05	3	120	2	27816501
Pubmed	Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice.	EPOR POLG	3.53e-05	3	120	2	25411424
Pubmed	Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.	SCN1A SCN2A	3.53e-05	3	120	2	19270815
Pubmed	Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.	SCN2A SCN3A	3.53e-05	3	120	2	16052353
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A SCN2A	3.53e-05	3	120	2	25155934
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A	3.53e-05	3	120	2	17928448
Pubmed	Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.	SCN1A SCN2A	7.05e-05	4	120	2	26637798
Pubmed	Regulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1.	RALGDS NEDD4	7.05e-05	4	120	2	28405688
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A	7.05e-05	4	120	2	21156207
Pubmed	NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway.	SAV1 NEDD4	7.05e-05	4	120	2	25692647
Pubmed	Red blood cell β-adrenergic receptors contribute to diet-induced energy expenditure by increasing O2 supply.	EPOR ADRB3	1.17e-04	5	120	2	28724789
Pubmed	Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.	POLG GADD45GIP1	1.17e-04	5	120	2	27986797
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN3A	1.17e-04	5	120	2	17724025
Pubmed	Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.	NEDD4 SCN3A	1.17e-04	5	120	2	15548568
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	NEDD4 UBR5	1.17e-04	5	120	2	28425671
Pubmed	PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1.	NEDD4 ROBO1	1.17e-04	5	120	2	33037408
Pubmed	NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor.	DVL2 NEDD4	1.17e-04	5	120	2	31867777
Pubmed	A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.	NEDD4 ROBO1	1.17e-04	5	120	2	36002265
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	C15orf62 TMEM61 MAP1A MRPL43 NEDD4 SCN1A DYNC1H1 GAREM1	1.29e-04	430	120	8	35044719
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MAP1A RNF213 UBR5 DYNC1H1	1.43e-04	76	120	4	27542412
Pubmed	Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma.	DVL2 WNT10A	1.75e-04	6	120	2	18787224
Pubmed	Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.	ERVV-2 ERVV-1	1.75e-04	6	120	2	23085571
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	NR2E3 ZNF408 MVK ZNF513	1.83e-04	81	120	4	20301590
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MXRA5 RNF213 ZNF831 PGF ZNF408 SCN3A NUP188 ARHGAP20 DYNC1H1 PLXNB3	2.43e-04	736	120	10	29676528
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A	2.45e-04	7	120	2	25818041
Pubmed	EphB regulates L1 phosphorylation during retinocollicular mapping.	EPHB3 NRCAM	2.45e-04	7	120	2	22579729
Pubmed	Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes.	NPR2 NR2E3	2.45e-04	7	120	2	10493779
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	USP9X WRNIP1 RNF213 IBTK UBR5 UBASH3B PALLD TEX19	2.75e-04	481	120	8	28190767
Pubmed	Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.	MYPN PALLD	3.26e-04	8	120	2	11309420
Pubmed	Syncytins expressed in human placental trophoblast.	ERVV-2 ERVV-1	3.26e-04	8	120	2	33504453
Pubmed	Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.	NPR2 NRCAM	3.26e-04	8	120	2	16461637
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZWILCH POLG SANBR FUZ PFAS CNTROB NEDD4 FLAD1 SMPD1 SPIDR MVK	3.70e-04	925	120	11	28986522
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FUZ KIF7 QSOX1 ROBO1	4.09e-04	100	120	4	25807483
Pubmed	Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase.	SMPD4 SMPD1	4.18e-04	9	120	2	15509740
Pubmed	Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma.	UBR5 SPIDR	4.18e-04	9	120	2	30836988
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	NRCAM MAP1A USP9X NEDD4 UBR5 DYNC1H1	4.46e-04	281	120	6	28706196
Pubmed	Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.	MAP1A SCN2A DYNC1H1	4.47e-04	43	120	3	36950384
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARHGEF19 POLG PFAS TESK1 CNTROB CNPPD1 ZNF408 DIP2C NUP188 DYNC1H1 TEX19 GAREM1	4.51e-04	1105	120	12	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NRCAM USP9X SENP3 DVL2 KIF7 NEDD4 UBR5 ZSCAN18 UBASH3B DYNC1H1 ANKS1A	5.18e-04	963	120	11	28671696
Pubmed	Common variants associated with general and MMR vaccine-related febrile seizures.	SCN1A SCN2A	5.22e-04	10	120	2	25344690
Pubmed	Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.	SCN1A SCN2A	5.22e-04	10	120	2	20602612
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRCAM IGDCC4 NEDD4 UBR5 STARD9 DYNC1H1 PLXNB3	5.47e-04	407	120	7	12693553
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	MAP1A USP9X SMCHD1 PFAS UBR5 NUP188 PALLD DYNC1H1	5.48e-04	534	120	8	35032548
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	REC8 AMHR2 USP9X ICE2 SAV1 PFAS UBR5 ZNF408 SMPD1 NUP188 ALOX12 TEX19 ANKS1A	6.84e-04	1327	120	13	32694731
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SENP3 DVL2 WRNIP1 SMPD4 GADD45GIP1 KIF7 UBR5 AP5Z1 SPIDR DYNC1H1	7.95e-04	857	120	10	25609649
Pubmed	Testis determination requires insulin receptor family function in mice.	AMHR2 INSRR	8.98e-04	13	120	2	14628051
Pubmed	Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.	DVL2 NEDD4	8.98e-04	13	120	2	23146885
Cytoband	17p13.1	DVL2 PFAS CNTROB RANGRF ALOX12	1.61e-05	118	121	5	17p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	SENP3 DVL2 PFAS CNTROB RANGRF ALOX12	3.26e-04	346	121	6	chr17p13
Cytoband	2q24.3	SCN1A SCN2A	8.07e-04	16	121	2	2q24.3
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MXRA5 NRCAM IGDCC4 HMCN1 MYPN ROBO1 PALLD	3.88e-06	161	73	7	593
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN3A	5.21e-06	9	73	3	1203
GeneFamily	Fibronectin type III domain containing	EPHB3 EPOR NRCAM INSRR IGDCC4 ROBO1	4.56e-05	160	73	6	555
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	EPOR SANBR ZNF831 STARD9 GPR137B PBXIP1 NOTCH4	3.64e-07	166	121	7	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ASB16-AS1 EPOR POLG IGDCC4 SSC5D SCN2A ARHGAP20	7.54e-07	185	121	7	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ASB16-AS1 EPOR POLG IGDCC4 SSC5D SCN2A ARHGAP20	7.54e-07	185	121	7	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRCAM IGDCC4 KIAA1755 ROBO1 SPIDR ARHGAP20 PALLD	9.02e-07	190	121	7	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 C17orf99 TOP6BL SCN2A ACKR1 GAREM1	2.86e-06	145	121	6	fd02d55755c35288a42ab08a82450b370aad35a7
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EPOR SANBR ZNF831 STARD9 GPR137B NOTCH4	7.64e-06	172	121	6	a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	EPOR SANBR ZNF831 STARD9 GPR137B NOTCH4	8.43e-06	175	121	6	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH1 PGF C16orf89 HMCN1 HFM1 ALOX12	8.71e-06	176	121	6	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH1 PGF C16orf89 HMCN1 HFM1 ALOX12	8.71e-06	176	121	6	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PFAS C16orf89 QSOX1 SLC9A3 HMCN1 ACKR1	9.29e-06	178	121	6	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PFAS C16orf89 QSOX1 SLC9A3 HMCN1 ACKR1	9.29e-06	178	121	6	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NR2E3 NRCAM ZSCAN18 DIP2C ROBO1 UBASH3B	1.05e-05	182	121	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRCAM SANBR HMCN1 UBR5 SPIDR PALLD	1.27e-05	188	121	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRCAM SANBR HMCN1 UBR5 SPIDR PALLD	1.27e-05	188	121	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRCAM SANBR HMCN1 UBR5 SPIDR PALLD	1.27e-05	188	121	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	MXRA5 NRCAM HMCN1 DIP2C ROBO1 PALLD	1.65e-05	197	121	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRCAM SSC5D HMCN1 IL21R UBASH3B PALLD	1.65e-05	197	121	6	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	MXRA5 SEZ6L2 SSC5D HMCN1 ROBO1 PALLD	1.70e-05	198	121	6	196257c4420ac801ed9fbb444f11718adb7560ae
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRCAM HIF3A ABCC8 SCN1A PCDHGC3 PLXNB3	1.75e-05	199	121	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRCAM HIF3A ABCC8 SCN1A PCDHGC3 PLXNB3	1.75e-05	199	121	6	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AMHR2 DCDC1 C16orf89 SSC5D ACKR1	2.44e-05	126	121	5	10e1448a03f79965b72922fd83ef51de1b7b474f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PGF SLC5A11 STARD9 MYPN ROBO1	4.04e-05	140	121	5	2c44e8cc5190226049be7ebc465d685393e701c4
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	C17orf99 RBBP8NL SLC5A11 STARD9 ZSCAN18	5.79e-05	151	121	5	8ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SENP3 TOP6BL SCN2A DIP2C GAREM1	5.79e-05	151	121	5	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM IGDCC4 SCN2A SCN3A GAREM1	5.98e-05	152	121	5	eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCell	COVID_non-vent-Lymphocytic-Dendritic-pDC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MAP1A ACKR1 PCDHGC3 NOTCH4 LILRA4	7.62e-05	160	121	5	61f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCell	COVID_non-vent-Lymphocytic-Dendritic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MAP1A ACKR1 PCDHGC3 NOTCH4 LILRA4	7.62e-05	160	121	5	34b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	REC8 SLC9A3 UBR5 SCN1A UBASH3B	7.84e-05	161	121	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PGF KIF7 ABCC8 ROBO1 PALLD	8.56e-05	164	121	5	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LVRN EPOR PGF SSC5D ROBO1	8.81e-05	165	121	5	e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LVRN EPOR PGF SSC5D ROBO1	8.81e-05	165	121	5	b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LVRN EPOR PGF SSC5D ROBO1	8.81e-05	165	121	5	d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell	Influenza_Severe-pDC\|Influenza_Severe / Disease group and Cell class	MAP1A C17orf99 ZSCAN18 NOTCH4 LILRA4	9.06e-05	166	121	5	b43a5cd4d28118cf6e56a435deb8ea9435608a90
ToppCell	-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	LVRN MXRA5 JSRP1 IGDCC4 KIAA1755	9.06e-05	166	121	5	bc9323de1373fdc0357e6bb46874f6c4787443a9
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	THEMIS2 MAP1A FUZ WNT10A LILRA4	9.32e-05	167	121	5	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NR2E3 TMEM61 SSC5D HMCN1	9.75e-05	88	121	4	1ca0e16981e88030987412e12838a9797b97b9c9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPOR MXRA5 NRCAM TOP6BL SCN2A	1.01e-04	170	121	5	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRCAM SSC5D HMCN1 ROBO1 PALLD	1.16e-04	175	121	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	Posterior_cortex-Macroglia\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ARHGEF19 SLC5A11 ABHD4 FAM83D PLXNB3	1.16e-04	175	121	5	8bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	THEMIS2 NRCAM GPR137B UBASH3B LILRA4	1.26e-04	178	121	5	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	AMHR2 KIF7 ROBO1 HFM1 ARHGAP20	1.26e-04	178	121	5	b8c301d65c0f37941e8e9414d55e90edb6ecc195
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRCAM SSC5D MYPN FAM83D PALLD	1.26e-04	178	121	5	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRCAM SSC5D MYPN FAM83D PALLD	1.26e-04	178	121	5	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM TOP6BL SCN2A SCN3A GAREM1	1.29e-04	179	121	5	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SASH1 C16orf89 HMCN1 ARHGAP20 ACKR1	1.32e-04	180	121	5	178648429686e6d4e6f3aafc350130e819788ecf
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SASH1 C16orf89 HMCN1 ARHGAP20 ACKR1	1.32e-04	180	121	5	fcd5d5bf00ee728162b0aac4c81eb78e742cf6f2
ToppCell	facs-Lung-24m-Endothelial-venous_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SASH1 C16orf89 HMCN1 ARHGAP20 ACKR1	1.32e-04	180	121	5	c2a8f61c806f6f6f47743e9f7c9700705db43386
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF7 C16orf89 KIAA1755 ROBO1 PALLD	1.32e-04	180	121	5	d1c52aeceb3627e3c5fb6cc3af77e0400f9380ab
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C16orf89 QSOX1 HMCN1 ARHGAP20 ACKR1	1.36e-04	181	121	5	72c28baf4fd417ff4a7068603830d55074960144
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C17orf99 PFAS UBR5 AACS GPR137B	1.36e-04	181	121	5	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NRCAM SSC5D ROBO1 UBASH3B PALLD	1.36e-04	181	121	5	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C17orf99 PFAS UBR5 AACS GPR137B	1.36e-04	181	121	5	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C16orf89 QSOX1 HMCN1 ARHGAP20 ACKR1	1.36e-04	181	121	5	2ac4d3e8987d5a009d7908d8787e18165826202a
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C16orf89 QSOX1 HMCN1 ARHGAP20 ACKR1	1.36e-04	181	121	5	2628c7ac345eaaeecf8e34617e81948925962cb9
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	LVRN ZNF831 PPARGC1B AACS ARHGAP20	1.43e-04	183	121	5	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	THEMIS2 MAP1A FUZ NOTCH4 LILRA4	1.43e-04	183	121	5	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF19 INSRR IGDCC4 SCN2A ROBO1	1.51e-04	185	121	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SAV1 NEDD4 UBASH3B ACKR1 NOTCH4	1.51e-04	185	121	5	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HIF3A SSC5D STARD9 KIAA1755 ROBO1	1.51e-04	185	121	5	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	critical-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAP1A TOP6BL JSRP1 WNT10A LILRA4	1.51e-04	185	121	5	4a5d1d0a757f1f4fdb911be96ed90b52182c25f0
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	NPR2 IGDCC4 SSC5D SCN2A ARHGAP20	1.54e-04	186	121	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JSRP1 IGDCC4 SSC5D HMCN1 SCN1A	1.54e-04	186	121	5	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	NPR2 IGDCC4 SSC5D SCN2A ARHGAP20	1.54e-04	186	121	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SASH1 HIF3A ABCC8 ACKR1 NOTCH4	1.58e-04	187	121	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	SASH1 HIF3A NEDD4 ABCC8 NOTCH4	1.58e-04	187	121	5	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TOP6BL HMCN1 SCN2A SCN3A GAREM1	1.58e-04	187	121	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	NRCAM SSC5D HMCN1 ROBO1 PALLD	1.58e-04	187	121	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	MXRA5 SSC5D HMCN1 PCDHGC3 PALLD	1.58e-04	187	121	5	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NR2E3 TMEM61 SSC5D HMCN1	1.60e-04	100	121	4	cb0deaf1c33d2789417e93cc01d94e34a611d20a
ToppCell	(0)_Myeloid-(011)_pDC\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	MAP1A SHF WNT10A NOTCH4 LILRA4	1.62e-04	188	121	5	a81b5d840490d6a636fe168f8cff2c4984369f09
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 SEZ6L2 PGF KIAA1755 ROBO1	1.62e-04	188	121	5	ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM TOP6BL SCN2A SCN3A GAREM1	1.62e-04	188	121	5	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS TESK1 WNT10A PALLD PBXIP1	1.66e-04	189	121	5	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM INSRR TOP6BL SCN2A SCN3A	1.66e-04	189	121	5	a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LVRN PGF IGDCC4 SSC5D KIAA1755	1.66e-04	189	121	5	d531399749409d614adca13d181830c6e3287508
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM TOP6BL SCN2A SCN3A GAREM1	1.66e-04	189	121	5	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THEMIS2 RNF213 IGDCC4 WNT10A GAREM1	1.66e-04	189	121	5	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TOP6BL HMCN1 SCN2A SCN3A GAREM1	1.66e-04	189	121	5	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHF ABCC8 SCN1A SCN2A ACKR1	1.66e-04	189	121	5	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THEMIS2 RNF213 IGDCC4 WNT10A GAREM1	1.66e-04	189	121	5	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CNPPD1 AP5Z1 GPR137B EEF1AKMT2 ACKR1	1.70e-04	190	121	5	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SASH1 HIF3A NEDD4 STARD9 NOTCH4	1.70e-04	190	121	5	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SASH1 HIF3A SLC5A11 KIAA1755 PLXNB3	1.70e-04	190	121	5	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	SASH1 HIF3A NEDD4 ABCC8 NOTCH4	1.75e-04	191	121	5	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGF NEDD4 SSC5D SCN3A KIAA1755	1.75e-04	191	121	5	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	SASH1 HIF3A ABCC8 ACKR1 NOTCH4	1.75e-04	191	121	5	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM TOP6BL SCN2A SCN3A GAREM1	1.75e-04	191	121	5	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	MXRA5 NRCAM TOP6BL SCN2A SCN3A	1.79e-04	192	121	5	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	Control-B_intermediate-10\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	THEMIS2 NRCAM GPR137B UBASH3B LILRA4	1.79e-04	192	121	5	224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SASH1 MAP1A SSC5D MYPN DLX4	1.83e-04	193	121	5	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)\|Adult / Lineage, Cell type, age group and donor	SASH1 HIF3A NEDD4 ABCC8 NOTCH4	1.83e-04	193	121	5	39c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SASH1 NEDD4 HMCN1 UBASH3B NOTCH4	1.83e-04	193	121	5	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	SASH1 HIF3A ABCC8 ACKR1 NOTCH4	1.83e-04	193	121	5	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	HIF3A HMCN1 ROBO1 ARHGAP20 PALLD	1.83e-04	193	121	5	acad568621ed677031797b8c2e34dafea798d681
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SASH1 HIF3A NEDD4 ABCC8 NOTCH4	1.83e-04	193	121	5	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SASH1 HIF3A ABCC8 ACKR1 NOTCH4	1.83e-04	193	121	5	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRCAM SSC5D HMCN1 ROBO1 PALLD	1.88e-04	194	121	5	8fae8061b350336299aa81f378e07deadbd55123
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 NRCAM TOP6BL SCN2A SCN3A	1.88e-04	194	121	5	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRCAM TOP6BL SCN2A SCN3A GAREM1	1.88e-04	194	121	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 TOP6BL QSOX1 SCN2A GAREM1	1.88e-04	194	121	5	4579b4a44f7c731553a284843c296866027d7c0e
Drug	Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; HL60; HG-U133A	EPOR ZC3H12A POLG TESK1 GADD45GIP1 RANGRF DIP2C SGSM3 MVK	8.11e-07	198	116	9	1772_UP
Drug	Leucomisine [17946-87-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A	ZC3H12A NRCAM MED16 FUZ GADD45GIP1 AP5Z1 SGSM3 PBXIP1	7.23e-06	195	116	8	3546_DN
Drug	Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A	EPHB3 EPOR RALGDS SASH1 FUZ SGSM3 SPIDR PBXIP1	7.51e-06	196	116	8	5669_DN
Drug	Doxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	EPOR MED16 POLG FUZ ABHD4 AP5Z1 SMPD1 GAREM1	8.09e-06	198	116	8	7415_DN
Drug	Sulfapyridine [144-83-2]; Up 200; 16uM; PC3; HT_HG-U133A	RALGDS SMCHD1 SENP3 FLAD1 SMPD1 SGSM3 PBXIP1 MVK	8.09e-06	198	116	8	7151_UP
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	EPOR RALGDS SASH1 DVL2 CNPPD1 SMPD1 SPIDR PBXIP1	8.39e-06	199	116	8	6950_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A	NPR2 ZC3H12A MED16 POLG FUZ SMPD1 ALOX12 GAREM1	8.70e-06	200	116	8	1164_UP
Drug	CID5208842	FUZ ACKR1	2.57e-05	2	116	2	CID005208842
Drug	STOCK1N-35215; Up 200; 10uM; MCF7; HT_HG-U133A	NR2E3 MED16 TOP6BL ABHD4 SCN1A SGSM3 PBXIP1	6.03e-05	193	116	7	6422_UP
Drug	STOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A	EPHB3 DVL2 PHF7 NUP188 SGSM3 ALOX12 MVK	6.23e-05	194	116	7	6380_DN
Drug	Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; HL60; HG-U133A	EPOR ZC3H12A DVL2 SAV1 IBTK DIP2C SPIDR	6.23e-05	194	116	7	1404_UP
Drug	estradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A	EPOR NPR2 MXRA5 DVL2 TOP6BL CNPPD1 PBXIP1	6.65e-05	196	116	7	373_DN
Drug	Prednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A	EPOR ZC3H12A SASH1 PAN2 SMPD1 MVK GAREM1	6.65e-05	196	116	7	7424_DN
Drug	Bicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	RALGDS SMCHD1 POLG CNPPD1 QSOX1 SGSM3 PBXIP1	6.87e-05	197	116	7	2796_DN
Drug	Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A	EPOR ATG2B CNPPD1 RANGRF PBXIP1 MVK GAREM1	6.87e-05	197	116	7	3417_DN
Drug	CP-863187 [668981-07-5]; Up 200; 10uM; MCF7; HT_HG-U133A	RALGDS NR2E3 MED16 SMCHD1 SENP3 CNPPD1 PBXIP1	7.09e-05	198	116	7	7508_UP
Drug	Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; HL60; HG-U133A	EPOR RALGDS ZC3H12A POLG PHF7 AP5Z1 DIP2C	7.09e-05	198	116	7	1412_UP
Drug	Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; HL60; HT_HG-U133A	ZC3H12A SASH1 CNPPD1 ZNF408 SMPD1 PBXIP1 MVK	7.09e-05	198	116	7	1299_DN
Drug	Piroxicam [36322-90-4]; Up 200; 12uM; HL60; HG-U133A	ZC3H12A MED16 FUZ IBTK AP5Z1 DIP2C SGSM3	7.09e-05	198	116	7	1405_UP
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; HL60; HT_HG-U133A	RALGDS DVL2 HIF3A CNPPD1 ZNF408 DLX4 MVK	7.32e-05	199	116	7	2402_DN
Drug	Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A	THEMIS2 EPHB3 PHF7 HIF3A SLC9A3 PBXIP1 MVK	7.32e-05	199	116	7	6524_UP
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN3A	6.96e-06	10	116	3	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN3A	6.96e-06	10	116	3	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN3A	1.27e-05	12	116	3	DOID:0060170 (implicated_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A SCN3A	8.63e-05	22	116	3	DOID:2030 (implicated_via_orthology)
Disease	uric acid measurement	DCDC1 INSRR TOP6BL CNTROB SHF DIP2C HFM1 UBASH3B RNF32-DT GAREM1	1.52e-04	610	116	10	EFO_0004761
Disease	Nemaline Myopathy, Childhood Onset	KLHL41 MYPN	3.18e-04	7	116	2	C0546125
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	3.18e-04	7	116	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	3.18e-04	7	116	2	C0751057
Disease	central serous retinopathy	RBBP8NL NOTCH4	4.22e-04	8	116	2	EFO_0009784
Disease	epilepsy (implicated_via_orthology)	NRCAM SCN1A SCN2A SCN3A DYNC1H1	4.74e-04	163	116	5	DOID:1826 (implicated_via_orthology)
Disease	Febrile Convulsions	SCN1A SCN2A	5.42e-04	9	116	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	5.42e-04	9	116	2	C3502809
Disease	interferon gamma measurement	IBTK PALLD ALOX12	1.07e-03	51	116	3	EFO_0008165
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	1.16e-03	13	116	2	C0751122
Disease	MMR-related febrile seizures	SCN1A SCN2A	1.56e-03	15	116	2	EFO_0006519
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	UBR5 WNT10A	1.77e-03	16	116	2	C0334634
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.77e-03	16	116	2	C0393706
Disease	esophageal carcinoma, gastric carcinoma	SASH1 ATG2B	2.00e-03	17	116	2	EFO_0000178, EFO_0002916
Disease	Lipidemias	PPARGC1B ADRB3	2.00e-03	17	116	2	C1706412
Disease	Hyperlipidemia	PPARGC1B ADRB3	2.00e-03	17	116	2	C0020473
Disease	Profound Mental Retardation	RALGDS KIF7 SCN1A DYNC1H1	2.25e-03	139	116	4	C0020796
Disease	Mental Retardation, Psychosocial	RALGDS KIF7 SCN1A DYNC1H1	2.25e-03	139	116	4	C0025363
Disease	Mental deficiency	RALGDS KIF7 SCN1A DYNC1H1	2.25e-03	139	116	4	C0917816
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	2.25e-03	18	116	2	HP_0002373
Disease	multiple sclerosis (is_implicated_in)	POLG IL21R NOTCH4	3.01e-03	73	116	3	DOID:2377 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSDLLFAPPALPALW	ERFL	6	A0A1W2PQ73
LLTALPPLWSSSLPG	C16orf89	11	Q6UX73
PPLWSSSLPGLDTAE	C16orf89	16	Q6UX73
PDLTAPDSTWILPIS	COX18	216	Q8N8Q8
WEAAALAESLPPPTL	C6orf226	61	Q5I0X4
GSPLVPTPNVLWDLV	AACS	356	Q86V21
GSLPEAQSLWPRPLF	SMPD1	616	P17405
LILVDPWGFPLRPTN	ABHD4	166	Q8TB40
ATRTLLPSLPLPEGW	ACKR1	311	Q16570
LPSLPLPEGWSSHLD	ACKR1	316	Q16570
LPSLNWFVPLLGPAT	ERVV-2	451	B6SEH9
WTAPELLSGNPLPTT	NPR2	686	P20594
SPPSVPSWLDSLGLQ	ANKS1A	771	Q92625
WNSPPLTSEFVALLP	AP5Z1	441	O43299
LLPGSPSLLLPAATW	ASB16-AS1	156	Q495Z4
LAPWPDLPTLAPNTA	ADRB3	11	P13945
LWPQLRPDELPAGSL	LVRN	111	Q6Q4G3
LPSLWDLPKAGTLPT	DLX4	201	Q92988
SDQDTLAPLPGATPW	DVL2	531	O14641
IFNDLLLWEPTAPSP	ATG2B	961	Q96BY7
GLWALLPTAVEAPPN	AMHR2	6	Q16671
AWLPLPPSLSNGQVV	IGDCC4	546	Q8TDY8
TPGPSLWIPLLLVAG	RNF32-DT	171	Q8NI28
TPTLSGWLPPELLGL	REC8	351	O95072
IQWSLPLDSCPLLAP	NR2E3	266	Q9Y5X4
SGSGPPPSLLLLLLW	QSOX1	6	O00391
WSQSLALPLALAVPP	KIAA0895L	41	Q68EN5
SSLGPENLSPAPWSL	RANGRF	151	Q9HD47
SLGTPAPLQGLLWPL	ARHGEF19	66	Q8IW93
LPCLVDSLPPLDWSQ	PAN2	376	Q504Q3
DSLPPLDWSQDLLPL	PAN2	381	Q504Q3
EFDWPIQGLLVPSSP	DCDC1	906	M0R2J8
QSPAGWSEPSDPLEL	LILRA4	101	P59901
WDLTPLSPAPPASLD	MAP1A	2301	P78559
PALSEELPWGDLSLN	JSRP1	111	Q96MG2
VLLPTSSGLPPGWEE	NEDD4	761	P46934
VNPTLDSLTLEWDPP	NRCAM	961	Q92823
ISDLPLLDSPNPWLS	IBTK	1256	Q9P2D0
WGPLPLEALDLSSPQ	KIAA1755	201	Q5JYT7
PSLTWFVPLLGPAAL	ERVV-1	451	B6SEH8
GPAALNSLLSPLWPL	ERVV-1	461	B6SEH8
SNPPPQDTLSWLPAL	ISM2	231	Q6H9L7
DPVLLSLSPRWGPQA	PLXNB3	926	Q9ULL4
SDLEPPLLELGWPAF	FAM83D	106	Q9H4H8
PWQPPADLSGLSIEE	GAREM1	801	Q9H706
DDPAWTPGPSLLSLQ	POLG	581	P54098
PELLWLSPLTEGAPR	KIF7	1246	Q2M1P5
LPLAAPLAEGWALPT	PDZD3	311	Q86UT5
LDSIASEWVGLPPLP	KLHL41	371	O60662
LSWAPPERPNGVILD	EPHB3	471	P54753
FLPSDPPLAWLLAKS	ALOX12	331	P18054
LPGAPILNLSVWDPD	PCDHGC3	471	Q9UN70
LSWFLPTEGSVPPPL	SMPD4	231	Q9NXE4
LLCESSGIPPPNLIW	HMCN1	2216	Q96RW7
PSQLLIPSLDWLPAS	MED16	721	Q9Y2X0
TLPSPSSWDLQPELA	NUTM1	556	Q86Y26
SLDWFLPPAPLISEI	HFM1	31	A2PYH4
LPTPDLSWQLDGKPV	PALLD	1161	Q8WX93
PLLLPSPGGWKAITE	RBBP8NL	146	Q8NC74
RSLWGSLLASLTPPP	CNPPD1	306	Q9BV87
DWQGPLESPILALPL	C17orf99	221	Q6UX52
SLSVPWVPLDPSLLL	ICE2	901	Q659A1
LLGSSDSPTWPPKVL	EEF1AKMT2	266	Q5JPI9
VKPSPWPLTGALSAL	MT-CO3	11	P00414
PPSELETNPALWLLA	DIP2C	1206	Q9Y2E4
LQPSWPSPVVAENGL	RALGDS	361	Q12967
SVLLRWLEPPDPNGL	INSRR	831	P14616
LLPDTQTPSWLGLPN	DYNC1H1	4311	Q14204
WSEPVSLLTPSDLDP	EPOR	236	P19235
VPGSLWPSPEQLREL	GADD45GIP1	71	Q8TAE8
LELGPWSPEVPSTLE	IL21R	301	Q9HBE5
RQPDPSAWLSSGPEL	C1orf127	506	Q8N9H9
WLLQVPSTQDPLFPG	FLAD1	46	Q8NFF5
WDEANQLLSTTLPPP	CNTROB	561	Q8N137
EAVLLPWLVGSLPPQ	FUZ	201	Q9BT04
WDPARNDSLPPTLTP	GPR137B	21	O60478
SILWPPASSSPELEN	ARHGAP20	516	Q9P2F6
SPDPRSPKGWLVDLL	USP9X	211	Q93008
LSAVAPQILLPGWPD	MRPL43	161	Q8N983
LSLAESLWTSKPPPL	PWWP2A	251	Q96N64
SGPPAKLLLIDWPEL	SMCHD1	1251	A6NHR9
GPLGLPLILSTWEQP	TOP6BL	251	Q8N6T0
WPEPSLLEKPESSRG	PHF7	346	Q9BWX1
SPPALEPSLLPRWGS	HIF3A	531	Q9Y2N7
SLLARLPPWLSPGET	SLC9A3	766	P48764
LGPWLTFADEPLVPS	PPARGC1B	486	Q86YN6
PFSALTPSIWPQEIL	SGSM3	11	Q96HU1
EWLTSEPGLPLLETQ	SMIM28	21	A0A1B0GU29
FRDPLTSDLPWPGVL	SLC5A11	261	Q8WWX8
AIQSLGPLEDPSWAL	CCT8L1P	151	A6NM43
AIQSLGPLEDPSWAL	CCT8L2	151	Q96SF2
WDGLLAPILNSAPPD	SCN3A	1711	Q9NY46
LSEPAGVVLSPDWPQ	SEZ6L2	531	Q6UXD5
DPWSLLAVLGAPVPS	SKIV2L	86	Q15477
PWNPLSSSLQPPLLE	STARD9	1731	Q9P2P6
DGAPWPGLLLELSPS	SSC5D	136	A1L4H1
LLEPNTPWGPKTGEL	SANBR	521	Q6NSI8
PEWGPSLALLVVLSP	NOTCH4	1291	Q99466
WDGLLAPILNSKPPD	SCN1A	1726	P35498
EGLLAPSLIPKNWPD	ABCC8	1326	Q09428
LWGDEQPRATLLAPP	C15orf62	66	A8K5M9
LTNHGSEDLPLPPGW	SAV1	191	Q9H4B6
LRWTPKSPLDPDSGL	SENP3	226	Q9H4L4
SRDALLSTQPAWPPP	TMEM61	161	Q8N0U2
LPPSLIPLVWDFGQL	RNF213	2571	Q63HN8
DGNLELLTRPDTPPW	RNF213	3646	Q63HN8
GTGSEPLPELLFPWT	ZNF513	301	Q8N8E2
SPLGEWTDPALPLEN	SHF	306	Q7M4L6
WSPVDEILQIPPLSS	ZWILCH	231	Q9H900
GPTDWLPQTLDSLPY	ZC3H12A	416	Q5D1E8
LPWAGQLTKELPLSP	PBXIP1	626	Q96AQ6
GLALPAVPPQQWALS	PGF	16	P49763
IFSLIDTLWPPAIPL	SPIDR	566	Q14159
LPSLDIVVWSELPPG	MVK	126	Q03426
PPPFDTLTTSPWLQL	PFAS	1311	O15067
PLQPGLLWGPLEEES	ZNF408	81	Q9H9D4
VLPGSELLLWPQPSS	ZNF408	161	Q9H9D4
ELLLWPQPSSEGPSL	ZNF408	166	Q9H9D4
PLLLSEVLAWEGPFP	THEMIS2	246	Q5TEJ8
WDGLLAPILNSGPPD	SCN2A	1716	Q99250
LADPSLPELFWGTEP	NUP188	411	Q5SRE5
RPPPWLSELPENTSL	SASH1	1056	O94885
TLEQLLSSPEPLSWP	TESK1	136	Q15569
RPGLLNISEPAAQPW	ROBO1	961	Q9Y6N7
LETNEIPSLILWGPP	WRNIP1	256	Q96S55
PSETPWLSPDPLFLE	ZSCAN18	181	Q8TBC5
LPAWIPPSELAAANL	UBASH3B	511	Q8TF42
PALPTASPGLQDSWE	WNT10A	196	Q9GZT5
EPWGNPPALEASLVT	ZNF831	691	Q5JPB2
PTELWPQEAVPLGLG	TEX19	121	Q8NA77
RDPDWLDLPPISSLG	UBR5	831	O95071
LLDESSGPPSQLLWT	ZNF311	6	Q5JNZ3
VATGLPNPEISWSLP	MXRA5	2266	Q9NR99
PNPEISWSLPDGSLV	MXRA5	2271	Q9NR99
VSGLPPPELTWLLNG	MYPN	1096	Q86TC9