Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoliver fibrosis

ALMS1 GBE1 PYGL C5 F5

2.85e-0677415MP:0003333
DomainA2M_N

C5 PZP

2.75e-0410472PF01835
DomainCAP_GLY_2

KIF13B TBCE

2.75e-0410472PS50245
DomainA2M_N_2

C5 PZP

2.75e-0410472PF07703
DomainCAP-Gly_domain

KIF13B TBCE

2.75e-0410472IPR000938
DomainA2M_N

C5 PZP

2.75e-0410472IPR002890
DomainA-macroglobulin_rcpt-bd

C5 PZP

2.75e-0410472IPR009048
DomainALPHA_2_MACROGLOBULIN

C5 PZP

2.75e-0410472PS00477
DomainCAP_GLY

KIF13B TBCE

2.75e-0410472SM01052
DomainA2M_recep

C5 PZP

2.75e-0410472PF07677
DomainA2M_comp

C5 PZP

2.75e-0410472PF07678
DomainA2M

C5 PZP

2.75e-0410472PF00207
DomainCAP_GLY

KIF13B TBCE

2.75e-0410472PF01302
DomainA2M_N_2

C5 PZP

2.75e-0410472IPR011625
DomainA2M_comp

C5 PZP

2.75e-0410472IPR011626
Domain-

KIF13B TBCE

2.75e-04104722.30.30.190
DomainMacroglobln_a2

C5 PZP

2.75e-0410472IPR001599
DomainCAP_GLY_1

KIF13B TBCE

2.75e-0410472PS00845
DomainNeurexin-like

CADM1 GYPC

5.53e-0414472IPR003585
Domain4.1m

CADM1 GYPC

5.53e-0414472SM00294
DomainTerpenoid_cyclase/PrenylTrfase

C5 PZP

9.24e-0418472IPR008930
Domain-

GALC GBE1

3.50e-03354723.20.20.80
DomainGlyco_hydro_catalytic_dom

GALC GBE1

4.11e-0338472IPR013781
DomainGlycoside_hydrolase_SF

GALC GBE1

7.87e-0353472IPR017853
Domainzf-C2H2_6

ZNF658 ZNF607 ZNF561 ZNF700

7.92e-03314474PF13912
DomainKRAB

ZNF658 ZNF607 ZNF561 ZNF700

1.24e-02358474PS50805
DomainKRAB

ZNF658 ZNF607 ZNF561 ZNF700

1.24e-02358474PF01352
DomainKRAB

ZNF658 ZNF607 ZNF561 ZNF700

1.37e-02369474SM00349
DomainKRAB

ZNF658 ZNF607 ZNF561 ZNF700

1.38e-02370474IPR001909
DomainZnf_C2H2-like

ZNF385D ZNF658 ZNF607 ZNF561 ZNF700 KLF4

1.43e-02796476IPR015880
DomainZnf_C2H2

ZNF385D ZNF658 ZNF607 ZNF561 ZNF700 KLF4

1.50e-02805476IPR007087
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

FREM2 PTPRJ CPB2 C5 PZP F5

1.86e-0625750616335952
Pubmed

Thrombin-activatable fibrinolysis inhibitor antigen and TAFI activity in patients with APC resistance caused by factor V Leiden mutation.

CPB2 F5

2.03e-06250212165290
Pubmed

Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.

CPB2 C5

2.03e-06250217105819
Pubmed

Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V.

C5 F5

2.03e-0625028900278
Pubmed

Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.

CPB2 F5

6.07e-06350212368162
Pubmed

Procarboxypeptidase U (TAFI) contributes to the risk of thrombosis in patients with hereditary thrombophilia.

CPB2 F5

6.07e-06350219195685
Pubmed

Carboxypeptidase B2 and N play different roles in regulation of activated complements C3a and C5a in mice.

CPB2 C5

6.07e-06350229383821
Pubmed

Carboxypeptidase B2 deficiency reveals opposite effects of complement C3a and C5a in a murine polymicrobial sepsis model.

CPB2 C5

6.07e-06350225851247
Pubmed

Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer.

PTPRJ C5

6.07e-0635028577718
Pubmed

Enhanced abdominal aortic aneurysm formation in thrombin-activatable procarboxypeptidase B-deficient mice.

CPB2 C5

6.07e-06350220431069
Pubmed

Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.

CPB2 PZP

6.07e-0635028662763
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PRUNE2 KIF13B ALMS1 ATP11A MBD5 RAB21 YTHDC1

6.50e-0649350715368895
Pubmed

Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N.

CPB2 C5

1.21e-05450211939578
Pubmed

Dominant role of the protein-tyrosine phosphatase CD148 in regulating platelet activation relative to protein-tyrosine phosphatase-1B.

PTPRJ KLF4

1.21e-05450223065825
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

FREM2 THY1 PTPRJ GBE1 PYGL CPB2 C5 PZP RAB21

1.92e-05107050923533145
Pubmed

Preeclampsia and its interaction with common variants in thrombophilia genes.

CPB2 F5

3.03e-05650215333035
Pubmed

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

CCNT2 ALMS1 PER2 GYPC YTHDC1 ERLEC1

4.03e-0544250615815621
Pubmed

Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2.

PTPRJ C5

4.23e-0575021347918
Pubmed

An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer.

THY1 KLF4

5.64e-05850220043075
Pubmed

ABO blood group but not haemostasis genetic polymorphisms significantly influence thrombotic risk: a study of 180 homozygotes for the Factor V Leiden mutation.

CPB2 F5

5.64e-05850217107352
Pubmed

LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer.

THY1 C5

5.64e-05850229336888
Pubmed

The DNA sequence and analysis of human chromosome 13.

FREM2 CPB2 ATP11A CCDC168

1.06e-0417050415057823
Pubmed

Gene variants associated with venous thrombosis: confirmation in the MEGA study.

CPB2 F5

1.32e-041250220128871
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

S100A6 FSIP2 THY1 ANK2 CTNND2 TBCE

1.45e-0455850635063084
Pubmed

Multiple loci influencing hippocampal degeneration identified by genome scan.

METTL8 F5

1.56e-041350222745009
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

KIF13B CADM1 ANK2 FAM171A2 PTPRJ ATP11A

1.61e-0456950630639242
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SDK2 THY1 CTNND2 YTHDC1 F5

1.69e-0436150526167880
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

CTNND2 BSN

1.82e-041450216452088
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

CPB2 C5 PZP

1.90e-047750316944957
Pubmed

Genetic predictors of fibrin D-dimer levels in healthy adults.

PTPRJ F5

2.40e-041650221502573
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

CADM1 FLCN C5 CTNND2 BSN RAB21

2.98e-0463850631182584
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

ZNF607 GBE1 CXorf58 C5 RAB21 ERLEC1

4.38e-0468650629987050
Pubmed

Circular RNA profile in liver tissue of EpCAM knockout mice.

THY1 PYGL

4.59e-042250231524221
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 ALMS1 PER2

4.60e-041045039205841
Pubmed

Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity.

GALC CCDC168

5.03e-042350222792062
Pubmed

Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.

GBE1 PYGL

5.48e-042450217937387
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

S100A6 THY1 PTPRJ GBE1 C5 MBD5 RAB21

5.94e-04101650719056867
Pubmed

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.

TTLL5 KLF4

5.95e-042550229593216
Pubmed

Same but different - Molecular comparison of human KTI12 and PSTK.

FAM171A2 KTI12

6.95e-042750233417976
Pubmed

Characterising the dynamics of placental glycogen stores in the mouse.

GBE1 PYGL

8.02e-042950232798765
Pubmed

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.

FREM2 CADM1 CTNND2

8.80e-0413050328705898
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KIF13B ANK2 ZNF658 ATP11A BSN KLF4 RAB21 ERLEC1

9.74e-04144250835575683
Pubmed

Lynch Syndrome

PTPRJ FLCN

1.04e-033350220301390
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

PRUNE2 GALC GBE1 PYGL

1.07e-0331350420800603
Pubmed

Early embryonic expression of murine coagulation system components.

CPB2 F5

1.10e-033450211154109
Pubmed

Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.

BSN YTHDC1

1.17e-033550237269288
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

ALMS1 PER2 FLCN

1.23e-0314650329688375
Pubmed

Identification and applications of repetitive probes for gene mapping in the mouse.

THY1 C5

1.38e-03385021673105
InteractionCPB2 interactions

CPB2 C5 PZP

1.27e-0519493int:CPB2
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C5 PZP

9.51e-0593021234
GeneFamilyImmunoglobulin like domain containing

SDK2 CADM1 THY1

3.93e-03193303594
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF658 ZNF607 ZNF561 ZNF700 KLF4

6.08e-0371830528
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FSIP2 SDK2 ZNF607 PYGL KLF4

9.06e-07157505a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B GALC THY1 CSGALNACT1 ERLEC1

1.23e-06167505961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B GALC THY1 CSGALNACT1 ERLEC1

1.23e-061675053760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellIPF-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

S100A6 KIF13B CADM1 PTPRJ PZP

2.50e-061935053c8a022dbd4f8d25b14fd137ce64c2713a7dbe41
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FREM2 CADM1 CPB2 ATP11A C5

2.90e-061995052dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellfacs-Liver|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMDHD1 PYGL CPB2 PZP

2.97e-05158504ea7db6bd9742153ceb6e444892a6d1df9c7fcc96
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CADM1 METTL8 C5 F5

3.05e-05159504b05fda31b77536a1878f55d3199563b53f9420b2
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 KIF13B PTPRJ KLF4

3.28e-05162504bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCelldroplet-Spleen-nan-21m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 CADM1 PYGL CTNND2

3.52e-05165504fbd84f211ad645c91b9f45a0815391606f3206ac
ToppCelldroplet-Spleen-nan-21m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 CADM1 PYGL CTNND2

3.52e-051655046fbdfacb49e627712ac999d40ae22dcb390edd3e
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GALC ZNF607 C5 KLF4

3.69e-05167504881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 PYGL CPB2 PZP

3.78e-05168504b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 PYGL CPB2 PZP

3.78e-05168504073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

CADM1 ANK2 PTPRJ CTNND2

4.24e-051735046fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

AMDHD1 CPB2 C5 PZP

4.33e-051745045aa2fb631505600f37d2b87b02def7be139dc262
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMDHD1 GBE1 PYGL CPB2

4.43e-051755045c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

AMDHD1 CPB2 C5 PZP

4.53e-05176504b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D CADM1 ANK2 GBE1

4.94e-051805049e09b3dfe344b5d50520711513d389865d73a861
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 ATP11A C5 CTNND2

5.38e-05184504fa4915b0498f3069fd5ef497286445528f75187e
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 ZNF607 CXorf58 ATP11A

5.50e-05185504636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 CADM1 ATP11A C5

5.61e-051865044e94158db52df41d71e67b02b9895a358eebee0f
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 ANK2 CTNND2 BSN

5.61e-05186504b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FREM2 ATP11A C5 CTNND2

5.73e-05187504db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 CADM1 ATP11A C5

5.73e-0518750458d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 ANK2 CTNND2 BSN

5.85e-05188504c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FREM2 CADM1 ATP11A C5

6.10e-051905048aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellCOPD-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

S100A6 KIF13B PTPRJ PZP

6.10e-0519050410bece40d980d37a01dae8ce887655bf9f93040c
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

S100A6 ZNF385D THY1 ANK2

6.10e-05190504799351fea7490d4159271d020c43c845ef37c788
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FREM2 CADM1 ATP11A C5

6.22e-0519150434cc997e4e5c727495f321e6807a84aa124da486
ToppCellControl-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

S100A6 KIF13B CADM1 PZP

6.22e-05191504ff7204f9b645233548cf804cf6fe0c86417be87f
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRUNE2 ZNF385D PYGL CSGALNACT1

6.35e-05192504072281344d58e85c9a290750b488d0c101f75d54
ToppCellEnterocyte_Progenitors-C_06|Enterocyte_Progenitors / shred on cell type and cluster

S100A6 PRUNE2 CADM1 CSGALNACT1

6.35e-05192504b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

CADM1 ANK2 GBE1 CTNND2

6.48e-05193504dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S100A6 PRUNE2 FSIP2 KLF4

6.61e-0519450449cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S100A6 PRUNE2 FSIP2 KLF4

6.61e-05194504fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell18-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

FREM2 CADM1 ATP11A C5

6.61e-05194504b45f1e80074a19245bc5dc4b3a583419a1904404
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

6.74e-051955040e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FREM2 CADM1 CPB2 ATP11A

6.88e-051965047e5addaa844e66f8160e05858c341866a80aed23
ToppCellwk_20-22-Epithelial-Distal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

6.88e-05196504cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S100A6 PRUNE2 FSIP2 KLF4

6.88e-05196504847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PRUNE2 CADM1 THY1 F5

6.88e-0519650424d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CADM1 CPB2 ATP11A C5

6.88e-05196504345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 CADM1 ANK2 PTPRJ

6.88e-05196504eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SDK2 ANK2 BSN PZP

7.01e-05197504fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D CADM1 GYPC CTNND2

7.01e-051975042e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCellwk_15-18-Epithelial-Distal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A CTNND2

7.01e-05197504b7aff83c27606d87565382a768119a863fe1c294
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FREM2 CADM1 CPB2 ATP11A

7.01e-05197504bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellControl-B_intermediate-0|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

S100A6 PTPRJ METTL8 CSGALNACT1

7.15e-0519850497e66b845053201247e2241739328cd73f33975c
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

7.15e-051985041851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

7.15e-0519850484697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellwk_15-18-Epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

7.15e-0519850412bbe77c3d68bf1e545949dbb1eb49ed3641de3d
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

7.15e-05198504eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A CTNND2

7.15e-05198504c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

FREM2 CADM1 CPB2 ATP11A

7.29e-051995049a65acfe9bf500db72142469cf17bf0973540001
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A C5

7.29e-05199504debdd7dba774d9ccff7effc3f4c132393d203dfa
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FREM2 CADM1 CPB2 ATP11A

7.29e-05199504a38a981cffa61c8444a980916de7414e689a1b63
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D THY1 GYPC CSGALNACT1

7.29e-05199504eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D CADM1 THY1 GYPC

7.29e-05199504e78f661b40da34768469549b6e755d330be6bbd8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SDK2 ANK2 GBE1 PZP

7.29e-051995048b86c69aaf60feff53aa782559cfece7342a23de
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GBE1 FAM149B1 ZNF700 TBCE

7.29e-051995046e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GBE1 FAM149B1 ZNF700 TBCE

7.29e-051995045f499595597c10857bba8272f62afe4d32d733ac
ToppCell3'_v3-bone_marrow-Myeloid_Monocytic-Classical_monocytes|bone_marrow / Manually curated celltypes from each tissue

S100A6 PYGL KLF4 F5

7.29e-0519950493f25e8f22deb438c930c2e95e572dbd16503f71
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

S100A6 PYGL KLF4 F5

7.44e-05200504621af09aae34226902c03edf556562f3ab35a7d8
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385D SDK2 PYGL CSGALNACT1

7.44e-05200504b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385D SDK2 PYGL CSGALNACT1

7.44e-05200504f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

S100A6 PYGL KLF4 F5

7.44e-05200504e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellwk_08-11-Epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FREM2 CADM1 ATP11A CTNND2

7.44e-05200504445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385D SDK2 PYGL CSGALNACT1

7.44e-05200504b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

S100A6 PYGL KLF4 F5

7.44e-05200504b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FREM2 CADM1 CPB2 ATP11A

7.44e-05200504b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 ZNF385D CADM1 PZP

7.44e-0520050402cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

S100A6 KLF4 F5 CSGALNACT1

7.44e-05200504b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PYGL ATP11A KLF4 F5

7.44e-052005049e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385D SDK2 PYGL CSGALNACT1

7.44e-052005047c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CADM1 ATP11A C5

4.18e-041305036434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Adenocarcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

KIF13B AMDHD1 CSGALNACT1

4.37e-041325036480feb3e4e898d610615ce14f598f419c623e07
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THY1 TASP1 MBD5

5.19e-0414050311e441c3435ad8911ab401ca7d4ae1d3e5fa6eac
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THY1 TASP1 MBD5

5.19e-0414050394444b92acfad64d811ebb1545dc1dab64473795
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

CADM1 CPB2 CTNND2

5.98e-04147503baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FREM2 SDK2 THY1

6.35e-04150503744050a1b665c6989f37141348af3df7579a73c9
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SDK2 ZNF607 PYGL

6.72e-0415350344572f87d403e314050ab935d2cd676c33d9c287
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

S100A6 PTPRJ PYGL

6.72e-04153503bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

ZNF385D THY1 CXorf58

6.85e-04154503afdc385397c7b13c9348eeef95f109f2363057ae
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FREM2 SDK2 THY1

6.85e-04154503874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CADM1 METTL8 F5

6.85e-041545039200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

CADM1 CPB2 CTNND2

7.11e-04156503afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

S100A6 PZP SPSB3

7.11e-041565036146232d55ef41b1d3c3d7de4d876dcb7fc76f6f
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 PYGL F5

7.24e-041575030673c7161c25feceee8f1e5fd237171576c42c6b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 PYGL F5

7.24e-04157503d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 CCDC168 F5

7.38e-04158503e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCelldroplet-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 CADM1 PYGL

7.38e-04158503e1a8dba5a88bc3ce112829c5ecb112cbbee5b078
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 PYGL PZP

7.38e-041585039f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 CCDC168 F5

7.38e-04158503d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCelldroplet-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S100A6 CADM1 PYGL

7.38e-0415850372e4f8ae137a7dddee0dc6236532e0711065e6af
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CADM1 METTL8 F5

7.51e-04159503ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 ZNF385D THY1

7.51e-041595037cda111bb98f1241989e49d490bdf51a712ea589
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THY1 TASP1 FAM149B1

7.65e-041605035c68d6a76c59e3a7e668ae5471396478a55756ac
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 PYGL F5

7.65e-04160503c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THY1 TASP1 FAM149B1

7.65e-041605030fee84844733d36805e1df90ca09478169746708
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRJ GYPC F5

7.79e-0416150352556b89808e551540f33a13f57417a6696c2438
DrugApUpG

GYPC PYGL CPB2

6.63e-0617503CID000165128
Drug5-Br

GYPC FLCN CPB2

1.11e-0520503CID000008057
DrugGpCpA

GYPC CPB2

1.42e-053502CID000168967
Diseasehippocampal atrophy

S100A6 PRUNE2 METTL8 F5

1.95e-0656474EFO_0005039
Diseaseunipolar depression, anorexia nervosa

CADM1 ERLEC1

1.11e-0410472EFO_0003761, MONDO_0005351
Diseaseacute lymphoblastic leukemia

PTPRJ PYGL CSGALNACT1

1.62e-0466473EFO_0000220
Diseasecervical carcinoma

PRUNE2 FSIP2 ALMS1 GBE1

2.03e-04182474EFO_0001061
DiseaseColorectal Carcinoma

ZNF385D ANK2 FLCN CTNND2 PZP F5

8.31e-04702476C0009402
DiseaseColorectal cancer

PTPRJ FLCN

8.50e-0427472cv:C0346629
DiseaseGlycogen Storage Disease

GBE1 PYGL

8.50e-0427472C0017919
DiseaseCOLORECTAL CANCER

PTPRJ FLCN

8.50e-0427472114500
DiseaseNeoplasm of the large intestine

PTPRJ FLCN

8.50e-0427472cv:C0009404
Diseaseloneliness measurement

PTPRJ GBE1 MBD5

1.03e-03124473EFO_0007865
DiseaseD dimer measurement

PTPRJ F5

1.05e-0330472EFO_0004507
Diseasefactor XI measurement, venous thromboembolism

PTPRJ F5

1.05e-0330472EFO_0004286, EFO_0004694
Diseasefactor VIII measurement, venous thromboembolism

PTPRJ F5

1.35e-0334472EFO_0004286, EFO_0004630

Protein segments in the cluster

PeptideGeneStartEntry
SDSQAAAHYKGTKHA

ZNF385D

91

Q9H6B1
HVHQYHEDKDSGKTS

ERLEC1

361

Q96DZ1
SDHSSVKQEYTHKAG

CCNT2

401

O60583
KTGPSGTKDNYHLHS

CXorf58

316

Q96LI9
GTLYELTFKGDHKHE

CSGALNACT1

221

Q8TDX6
PIGLSSSYSHSHKEK

ALMS1

1981

Q8TCU4
SGTYSHGENHKLVSE

ALMS1

2186

Q8TCU4
NATYHGAKGEHTSRK

CTNND2

1096

Q9UQB3
AESVGAKHYHTSAKQ

RAB21

151

Q9UL25
AKEGTHGSHVYTKAL

PZP

1141

P20742
KHGADQDAHTKLGYT

ANK2

716

Q01484
ESKHGSNHTSTYDKA

PTPRJ

576

Q12913
GCGKTYTKSSHLKAH

KLF4

436

O43474
GHPGYISHDKETSIK

FLCN

91

Q8NFG4
DSEKSAKHGSGAFYS

KTI12

191

Q96EK9
HTKDGSATSGEDYHP

FREM2

2291

Q5SZK8
ASSAYHHASDSKKGS

BSN

3711

Q9UPA5
ANVSSHEHTYKGKSS

FSIP2

1876

Q5CZC0
HEHTYKGKSSVTALD

FSIP2

1881

Q5CZC0
NKTKNRSHYSHESGE

PER2

521

O15055
RSHYSHESGEQKKKS

PER2

526

O15055
FDHYLGHKGAAEGKT

FAM171A2

481

A8MVW0
RHKGTYFTHEAKGAD

CADM1

401

Q9BY67
ISSHEGKVASYKHFT

GBE1

206

Q04446
KISKNTRYTHGHGSE

CPB2

346

Q96IY4
DKKFSYSSGHVHLSS

C5

61

P01031
AYALGKSHTHGSLEV

AMDHD1

371

Q96NU7
SSPSTKSDGHHQYKD

MBD5

506

Q9P267
RHKGTYHTNEAKGTE

GYPC

86

P04921
SSDSGKKAYTESLHG

CCDC168

4981

Q8NDH2
SHYGTKGLRKVTHES

BTBD2

476

Q9BX70
GAHYPGTHSAKDAKL

GALC

251

P54803
IKYSRSDGHGKTLSH

SDK2

1136

Q58EX2
DEKNHYEKSSGSSEG

METTL8

151

Q9H825
GKKLHFSSSYAHKAS

FAM149B1

186

Q96BN6
THTLYDVKSGTSGEK

KIF13B

231

Q9NQT8
ETGKYSEHSGTHQES

PRUNE2

1641

Q8WUY3
FHKYSGREGDKHTLS

S100A6

16

P06703
HAHGLSYEKSSEGKT

F5

1671

P12259
SYTGLLHHKGDKTSF

SPSB3

196

Q6PJ21
ESSHKTHYAVQDTKG

ATP11A

186

P98196
YGKDTLSVHKEASTG

ZNF561

151

Q8N587
SFQTHEKTHTGEKRY

ZNF700

376

Q9H0M5
RGKHDGSHEGTVYFK

TBCE

46

Q15813
ECGKGFSYSHKLTIH

ZNF607

481

Q96SK3
SKDEGTYTCALHHSG

THY1

96

P04216
GSSASESYAGSEKKH

YTHDC1

316

Q96MU7
GSEYGKTSHLKGHQR

ZNF658

496

Q5TYW1
AELKSYHQAHKATGG

THYN1

176

Q9P016
KAQVHAVSFYSKGHG

nan

186

Q5PR19
VHFYGKVEHTNTGTK

PYGL

201

P06737
VHAGAGYHSESKAKE

TASP1

46

Q9H6P5
GSCYLNKHHSGIAKT

TTLL5

996

Q6EMB2
GSEYGKTSHLKGHQR

ZNF658B

256

Q4V348