Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF355P ZNF536 ZNF878 ZNF560 ZNF584 ZNF780B ZNF184 GATA2 ZNF724 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 EP300 ZNF345

2.78e-0714595617GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF355P ZNF536 ZNF878 ZNF560 ZNF584 ZNF780B ZNF184 GATA2 ZNF724 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

9.98e-0714125616GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF355P ZNF536 ZNF584 ZNF780B ZNF184 GATA2 ZNF724 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 EP300 ZNF345

1.09e-0612445615GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF355P ZNF536 ZNF584 ZNF780B ZNF184 GATA2 ZNF724 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 EP300 ZNF345

1.43e-0612715615GO:0000987
GeneOntologyMolecularFunctionC-X3-C chemokine binding

ITGB1 ITGB3

7.68e-055562GO:0019960
GeneOntologyMolecularFunctionzinc ion binding

SETDB2 ADAMTS4 ADAMTS1 SYTL3 ZNF184 GATA2 BAZ1B GRIN2B EP300

7.73e-04891569GO:0008270
GeneOntologyBiologicalProcessregulation of postsynaptic neurotransmitter receptor diffusion trapping

ITGB1 ITGB3

2.09e-053552GO:0150054
GeneOntologyCellularComponentintegrin alpha9-beta1 complex

ITGB1 ITGB3

2.04e-053552GO:0034679
Domain-

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

3.99e-0967953143.30.160.60
Domainzf-C2H2

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

5.17e-096935314PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

5.27e-096945314IPR013087
Domainzf-C2H2_6

ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF107 ZNF345

1.61e-083145310PF13912
DomainZINC_FINGER_C2H2_2

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

2.13e-087755314PS50157
DomainZINC_FINGER_C2H2_1

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

2.20e-087775314PS00028
DomainZnf_C2H2-like

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

2.98e-087965314IPR015880
DomainZnf_C2H2

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

3.43e-088055314IPR007087
DomainZnF_C2H2

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

3.59e-088085314SM00355
DomainKRAB

ZNF878 ZNF560 ZNF584 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470

6.66e-07358539PS50805
DomainKRAB

ZNF878 ZNF560 ZNF584 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470

6.66e-07358539PF01352
DomainKRAB

ZNF878 ZNF560 ZNF584 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470

8.56e-07369539SM00349
DomainKRAB

ZNF878 ZNF560 ZNF584 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470

8.76e-07370539IPR001909
Domain-

ITGB1 ITGB3

4.72e-0545321.20.5.630
DomainACR

ADAMTS4 ADAMTS1 ADAM22

6.01e-0527533SM00608
DomainADAM_Cys-rich

ADAMTS4 ADAMTS1 ADAM22

6.01e-0527533IPR006586
DomainIntegrin_bsu_cyt_dom

ITGB1 ITGB3

1.18e-046532IPR014836
DomainIntegrin_b_cyt

ITGB1 ITGB3

1.18e-046532SM01241
DomainIntegrin_b_cyt

ITGB1 ITGB3

1.18e-046532PF08725
DomainIntegrin_bsu_tail

ITGB1 ITGB3

1.64e-047532IPR012896
DomainIntegrin_B_tail

ITGB1 ITGB3

1.64e-047532SM01242
DomainIntegrin_B_tail

ITGB1 ITGB3

1.64e-047532PF07965
DomainPeptidase_M12B_N

ADAMTS4 ADAMTS1 ADAM22

1.83e-0439533IPR002870
DomainPep_M12B_propep

ADAMTS4 ADAMTS1 ADAM22

1.83e-0439533PF01562
DomainDISINTEGRIN_1

ADAMTS4 ADAMTS1 ADAM22

1.98e-0440533PS00427
DomainReprolysin

ADAMTS4 ADAMTS1 ADAM22

1.98e-0440533PF01421
DomainADAM_MEPRO

ADAMTS4 ADAMTS1 ADAM22

1.98e-0440533PS50215
DomainDISINTEGRIN_2

ADAMTS4 ADAMTS1 ADAM22

1.98e-0440533PS50214
DomainPeptidase_M12B

ADAMTS4 ADAMTS1 ADAM22

1.98e-0440533IPR001590
DomainDisintegrin_dom

ADAMTS4 ADAMTS1 ADAM22

2.13e-0441533IPR001762
DomainIntegrin_beta

ITGB1 ITGB3

2.19e-048532PF00362
DomainINB

ITGB1 ITGB3

2.19e-048532SM00187
DomainIntegrin_bsu_VWA

ITGB1 ITGB3

2.19e-048532IPR002369
DomainIntegrin_bsu

ITGB1 ITGB3

2.81e-049532IPR015812
DomainIntegin_beta_N

ITGB1 ITGB3

2.81e-049532IPR033760
DomainINTEGRIN_BETA

ITGB1 ITGB3

2.81e-049532PS00243
DomainPSI_integrin

ITGB1 ITGB3

2.81e-049532PF17205
DomainSET

SETDB2 PRDM15 NSD3

3.00e-0446533SM00317
DomainSET_dom

SETDB2 PRDM15 NSD3

3.85e-0450533IPR001214
DomainSET

SETDB2 PRDM15 NSD3

3.85e-0450533PS50280
DomainEGF_extracell

ITGB1 ITGB3 ADAM22

6.59e-0460533IPR013111
DomainEGF_2

ITGB1 ITGB3 ADAM22

6.59e-0460533PF07974
DomainTSP_1

ADAMTS4 ADAMTS1 C6

7.60e-0463533PF00090
DomainEGF_1

SCUBE2 C6 ITGB1 ITGB3 ADAM22

7.67e-04255535PS00022
DomainZnf_FYVE_PHD

ATRX SYTL3 BAZ1B NSD3

8.00e-04147534IPR011011
DomainTSP1

ADAMTS4 ADAMTS1 C6

8.32e-0465533SM00209
DomainTSP1_rpt

ADAMTS4 ADAMTS1 C6

8.32e-0465533IPR000884
DomainTSP1

ADAMTS4 ADAMTS1 C6

8.32e-0465533PS50092
DomainEGF-like_CS

SCUBE2 C6 ITGB1 ITGB3 ADAM22

8.51e-04261535IPR013032
DomainGATA_ZN_FINGER_1

ATRX GATA2

9.24e-0416532PS00344
DomainGATA_ZN_FINGER_2

ATRX GATA2

9.24e-0416532PS50114
Domain-

COL28A1 ITGB1 ITGB3

1.21e-03745333.40.50.410
DomainMetalloPept_cat_dom

ADAMTS4 ADAMTS1 ADAM22

1.57e-0381533IPR024079
Domain-

ADAMTS4 ADAMTS1 ADAM22

1.57e-03815333.40.390.10
DomainVWFA

COL28A1 ITGB1 ITGB3

1.63e-0382533PS50234
DomainVWA

COL28A1 ITGB1 ITGB3

1.75e-0384533SM00327
DomainADAM_spacer1

ADAMTS4 ADAMTS1

1.92e-0323532IPR010294
DomainADAM_spacer1

ADAMTS4 ADAMTS1

1.92e-0323532PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS4 ADAMTS1

2.10e-0324532IPR013273
DomainEphrin_rec_like

ELAPOR2 SCUBE2

2.27e-0325532SM01411
DomainIntegrin_dom

ITGB1 ITGB3

2.27e-0325532IPR032695
DomainTyr-kin_ephrin_A/B_rcpt-like

ELAPOR2 SCUBE2

2.27e-0325532IPR011641
DomainBromodomain_CS

BAZ1B EP300

2.46e-0326532IPR018359
DomainZF_PHD_2

ATRX BAZ1B NSD3

2.48e-0395533PS50016
DomainZF_PHD_1

ATRX BAZ1B NSD3

2.56e-0396533PS01359
DomainZINC_PROTEASE

ADAMTS4 ADAMTS1 ADAM22

2.71e-0398533PS00142
DomainVWF_A

COL28A1 ITGB1 ITGB3

2.79e-0399533IPR002035
DomainBROMODOMAIN_1

BAZ1B EP300

4.94e-0337532PS00633
DomainBromodomain

BAZ1B EP300

5.20e-0338532PF00439
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF878 ZNF184 ZNF724 ZNF737 ZNF264 ZNF107

4.78e-0718156637372979
Pubmed

The ins and outs of HIV-1 Tat.

ITGB1 ITGB3 EP300

8.61e-071256321951552
Pubmed

β3 integrin is dispensable for conditioned fear and hebbian forms of plasticity in the hippocampus.

ITGB1 ITGB3

2.55e-06256222748100
Pubmed

Hyperhomocysteinemia suppresses bone marrow CD34+/VEGF receptor 2+ cells and inhibits progenitor cell mobilization and homing to injured vasculature-a role of β1-integrin in progenitor cell migration and adhesion.

ITGB1 CBS

2.55e-06256225854700
Pubmed

Pathogenic variants in EP300 and ANKRD11 in patients with phenotypes overlapping Cornelia de Lange syndrome.

ANKRD11 EP300

2.55e-06256232476269
Pubmed

Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.

ITGB1 ITGB3

2.55e-06256222511753
Pubmed

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β.

ITGB1 ITGB3

2.55e-06256224006485
Pubmed

Cooperation Between Platelet β1 and β3 Integrins in the Arrest of Bleeding Under Inflammatory Conditions in Mice-Brief Report.

ITGB1 ITGB3

2.55e-06256239145395
Pubmed

Activation of beta 1 but not beta 3 integrin increases cell traction forces.

ITGB1 ITGB3

2.55e-06256223395612
Pubmed

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.

ITGB1 ITGB3

2.55e-06256212690105
Pubmed

Spironolactone inhibits podocyte motility via decreasing integrin β1 and increasing integrin β3 in podocytes under high-glucose conditions.

ITGB1 ITGB3

2.55e-06256226352002
Pubmed

Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer.

ITGB1 ITGB3

2.55e-06256231618629
Pubmed

Integrins β1 and β3 are biomarkers of uterine condition for embryo transfer.

ITGB1 ITGB3

2.55e-06256227782833
Pubmed

β1A integrin is a master regulator of invadosome organization and function.

ITGB1 ITGB3

2.55e-06256220926684
Pubmed

Endothelial cell surface expression of protein disulfide isomerase activates β1 and β3 integrins and facilitates dengue virus infection.

ITGB1 ITGB3

2.55e-06256222422622
Pubmed

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins.

ITGB1 ITGB3

2.55e-06256218165225
Pubmed

SNPs in microRNA-binding sites in the ITGB1 and ITGB3 3'-UTR increase colorectal cancer risk.

ITGB1 ITGB3

2.55e-06256224777809
Pubmed

Novel focal adhesion protein kindlin-2 promotes the invasion of gastric cancer cells through phosphorylation of integrin β1 and β3.

ITGB1 ITGB3

7.63e-06356223857544
Pubmed

Regulation of ADAMTS-1, -4 and -5 expression in human macrophages: differential regulation by key cytokines implicated in atherosclerosis and novel synergism between TL1A and IL-17.

ADAMTS4 ADAMTS1

7.63e-06356223859810
Pubmed

Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and beta1 and beta3 integrins.

ITGB1 ITGB3

7.63e-06356218375753
Pubmed

Integrins control dendritic spine plasticity in hippocampal neurons through NMDA receptor and Ca2+/calmodulin-dependent protein kinase II-mediated actin reorganization.

ITGB1 ITGB3

7.63e-06356216467530
Pubmed

ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.

ITGB1 ITGB3

7.63e-06356216213489
Pubmed

Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina.

ADAMTS4 ADAMTS1

7.63e-06356221345877
Pubmed

Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis.

ITGB1 ITGB3

7.63e-06356224522833
Pubmed

Increased Expressions of Integrin Subunit β1, β2 and β3 in Patients with Acute Infection.

ITGB1 ITGB3

7.63e-06356226283883
Pubmed

Cellular tension encodes local Src-dependent differential β1 and β3 integrin mobility.

ITGB1 ITGB3

7.63e-06356230462575
Pubmed

Integrin expression profiling identifies integrin alpha5 and beta1 as prognostic factors in early stage non-small cell lung cancer.

ITGB1 ITGB3

7.63e-06356220565758
Pubmed

JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration.

ITGB1 ITGB3

7.63e-06356217099249
Pubmed

[Conformational regulation of integrin activation in drug discovery].

ITGB1 ITGB3

7.63e-06356224850451
Pubmed

Progesterone acts via the progesterone receptor to induce adamts proteases in ovarian cancer cells.

ADAMTS4 ADAMTS1

7.63e-06356226916548
Pubmed

Profilin 1-mediated cytoskeletal rearrangements regulate integrin function in mouse platelets.

ITGB1 ITGB3

7.63e-06356229739775
Pubmed

Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: evidence for specific and redundant patterns during ovulation.

ADAMTS4 ADAMTS1

7.63e-06356215659705
Pubmed

Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4.

ADAMTS4 ADAMTS1

7.63e-06356211278559
Pubmed

Salivary gland tumours: immunoexpression of integrins beta 1, beta 3 and beta 4.

ITGB1 ITGB3

7.63e-06356212694355
Pubmed

Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.

ITGB1 ITGB3

7.63e-06356218381073
Pubmed

Structural analysis of the sixth immunoglobulin-like domain of mouse neural cell adhesion molecule L1 and its interactions with alpha(v)beta3, alpha(IIb)beta3, and alpha5beta1 integrins.

ITGB1 ITGB3

7.63e-0635629832163
Pubmed

Functional regulation of GATA-2 by acetylation.

GATA2 EP300

7.63e-06356215001660
Pubmed

Human trophoblast cell adhesion to extracellular matrix protein, entactin.

ITGB1 ITGB3

7.63e-0635628831898
Pubmed

αvβ3 integrins negatively regulate cellular forces by phosphorylation of its distal NPXY site.

ITGB1 ITGB3

7.63e-06356227990663
Pubmed

Association of platelet glycoprotein receptor alpha2beta1 integrin and glycoprotein IIIa gene polymorphisms with diabetic retinopathy: evidence from 3007 subjects.

ITGB1 ITGB3

7.63e-06356224979111
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ACTL7A SETDB2 ZNF536 ADAMTS1 DNAJA2 BAZ1B DGKE EP300 UNC80 NSD3

1.04e-051116561031753913
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ELAPOR2 LRCH2 ZNF584 DNAJA2 ZNF724 PRDM15 CBS NSD3

1.40e-0568956836543142
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF355P ZNF727 ZNF107

1.40e-052956314563677
Pubmed

Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins.

ITGB1 ITGB3

1.52e-05456221325030
Pubmed

Mean platelet volume and integrin alleles correlate with levels of integrins α(IIb)β(3) and α(2)β(1) in acute coronary syndrome patients and normal subjects.

ITGB1 ITGB3

1.52e-05456222015659
Pubmed

Association of polymorphisms of platelet membrane integrins alpha IIb(beta)3 (HPA-1b/Pl) and alpha2(beta)1 (alpha807TT) with premature myocardial infarction.

ITGB1 ITGB3

1.52e-05456215978110
Pubmed

Examining the lineage autonomous role of β3-integrin in muscle regeneration.

ITGB1 ITGB3

1.52e-05456235734962
Pubmed

Regulation of integrin function by CD47 ligands. Differential effects on alpha vbeta 3 and alpha 4beta1 integrin-mediated adhesion.

ITGB1 ITGB3

1.52e-05456212218055
Pubmed

Absence of the alpha v beta 3 integrin dictates the time-course of angiogenesis in the hypoxic central nervous system: accelerated endothelial proliferation correlates with compensatory increases in alpha 5 beta 1 integrin expression.

ITGB1 ITGB3

1.52e-05456220087368
Pubmed

Adhesion of cultured human kidney mesangial cells to native entactin: role of integrin receptors.

ITGB1 ITGB3

1.52e-0545629686320
Pubmed

Surface-bound Tat inhibits antigen-specific CD8+ T-cell activation in an integrin-dependent manner.

ITGB1 ITGB3

1.52e-05456225313583
Pubmed

Murine leukemia retrovirus integration induces the formation of transcription factor complexes on palindromic sequences in the signal transducer and activator of transcription factor 5a gene during the development of pre-B lymphomagenesis.

GATA2 EP300

1.52e-05456221356387
Pubmed

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.

ITGB1 ITGB3

1.52e-05456223515331
Pubmed

Identification of an Arg-Gly-Asp (RGD) cell adhesion site in human immunodeficiency virus type 1 transactivation protein, tat.

ITGB1 ITGB3

1.52e-0545622202737
Pubmed

Structural diversity in integrin/talin interactions.

ITGB1 ITGB3

1.52e-05456221134644
Pubmed

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

ITGB1 ITGB3

1.52e-0545622116421
Pubmed

Binding of soluble fibronectin to integrin alpha5 beta1 - link to focal adhesion redistribution and contractile shape.

ITGB1 ITGB3

1.52e-05456218611961
Pubmed

The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions.

ITGB1 ITGB3

1.52e-05456225663698
Pubmed

Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption.

ITGB1 ITGB3

1.52e-05456221357746
Pubmed

Beta 1/beta 3 integrin ligation is uncoupled from ERK1/ERK2 activation in cytotoxic T lymphocytes.

ITGB1 ITGB3

1.52e-05456212629153
Pubmed

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.

GATA2 EP300

1.52e-05456211278891
Pubmed

Coxsackie adenovirus receptor (CAR) regulates integrin function through activation of p44/42 MAPK.

ITGB1 ITGB3

1.52e-05456219527712
Pubmed

Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function.

ITGB1 ITGB3

1.52e-05456227929375
Pubmed

ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells.

ITGB1 ITGB3

1.52e-05456212427871
Pubmed

Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.

ITGB1 ITGB3

1.52e-05456216731529
Pubmed

Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly.

ITGB1 ITGB3

1.52e-05456227003228
Pubmed

Identification of a novel binding site for platelet integrins alpha IIb beta 3 (GPIIbIIIa) and alpha 5 beta 1 in the gamma C-domain of fibrinogen.

ITGB1 ITGB3

1.52e-05456212799374
Pubmed

NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism.

EP300 NSD3

1.52e-05456224875858
Pubmed

Differential mRNA regulation of integrin subunits alpha V, beta 1, beta 3, and beta 5 during mouse embryonic organogenesis.

ITGB1 ITGB3

1.52e-0545628821033
Pubmed

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

ITGB1 ITGB3

1.52e-05456212486108
Pubmed

Monocyte-derived dendritic cells and monocytes migrate to HIV-Tat RGD and basic peptides.

ITGB1 ITGB3

1.52e-0545629517988
Pubmed

Polymorphisms of the human platelet alloantigens HPA-1, HPA-2, HPA-3, and HPA-4 in ischemic stroke.

ITGB1 ITGB3

1.52e-05456218383324
Pubmed

ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.

ADAMTS4 ADAMTS1

1.52e-05456210094461
Pubmed

Expression of integrins in cerebral arteriovenous and cavernous malformations.

ITGB1 ITGB3

1.52e-05456216385340
Pubmed

Association of CD98, integrin β1, integrin β3 and Fak with the progression and liver metastases of colorectal cancer.

ITGB1 ITGB3

1.52e-05456225041835
Pubmed

Human fallopian tube epithelium constitutively expresses integrin endometrial receptivity markers: no evidence for a tubal implantation window.

ITGB1 ITGB3

1.52e-05456222002573
Pubmed

Kindlin-3 is essential for integrin activation and platelet aggregation.

ITGB1 ITGB3

1.52e-05456218278053
Pubmed

Myosin-X provides a motor-based link between integrins and the cytoskeleton.

ITGB1 ITGB3

1.52e-05456215156152
Pubmed

Proteolytic cleavage of versican during limb joint development.

ADAMTS4 ADAMTS1

1.52e-05456220101710
Pubmed

HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies.

ITGB1 ITGB3

1.52e-05456223152803
Pubmed

Expression of ADAMTS-1, ADAMTS-4, ADAMTS-5 and TIMP3 by hepatocellular carcinoma cell lines.

ADAMTS4 ADAMTS1

1.52e-05456222735305
Pubmed

Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla.

ADAMTS4 ADAMTS1

1.52e-05456221584905
Pubmed

Angiogenic properties of human immunodeficiency virus type 1 Tat protein.

ITGB1 ITGB3

1.52e-0545627539135
Pubmed

ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia.

ADAMTS4 ADAMTS1

1.52e-05456229135310
Pubmed

Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.

ITGB1 ITGB3

2.54e-05556225398877
Pubmed

CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family.

ITGB1 ITGB3

2.54e-05556212695522
Pubmed

Phosphorylation of von Hippel-Lindau protein by checkpoint kinase 2 regulates p53 transactivation.

CHEK2 EP300

2.54e-05556222071692
Pubmed

IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis.

ITGB1 ITGB3

2.54e-0555629916748
Pubmed

Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.

ITGB1 ITGB3

2.54e-05556219805288
Pubmed

Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation.

ITGB1 ITGB3

2.54e-05556219843520
Pubmed

[ADAMTS family--new extracellular matrix degrading enzyme].

ADAMTS4 ADAMTS1

2.54e-05556211831030
Pubmed

Expression of selected adhesion molecules in dermatitis herpetiformis and bullous pemphigoid.

ITGB1 ITGB3

2.54e-05556219670701
Pubmed

Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins.

ITGB1 ITGB3

2.54e-05556218512729
Pubmed

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

ITGB1 ITGB3

2.54e-05556212364323
Pubmed

Thromboxane A2 receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: role of receptor internalization, thrombospondin-1, and alpha(v)beta3.

ITGB1 ITGB3

2.54e-05556214963009
Pubmed

Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.

ITGB1 ITGB3

2.54e-05556219469865
Pubmed

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.

ITGB1 ITGB3

2.54e-05556218086863
Pubmed

The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site.

ITGB1 ITGB3

2.54e-05556224789099
Pubmed

The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.

ITGB1 ITGB3

2.54e-05556210397733
Pubmed

Small Molecule MYC Inhibitor Conjugated to Integrin-Targeted Nanoparticles Extends Survival in a Mouse Model of Disseminated Multiple Myeloma.

ITGB1 ITGB3

2.54e-05556225824336
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF536 ZNF878 ZNF560 ZNF584 ZFP64 ZNF780B ZNF184 ZNF737 ZNF727 ZNF264 ZNF470 ZNF107 PRDM15 ZNF345

1.90e-10718401428
GeneFamilyCD molecules|Integrin beta subunits

ITGB1 ITGB3

1.70e-0494021159
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS4 ADAMTS1

7.97e-041940250
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETDB2 NSD3

2.56e-0334402487
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELAPOR2 GRIN2B TPPP3 KLKB1 UNC80

1.87e-06162565bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL28A1 GATA2 CHEK2 DGKE ITGB1

3.22e-0618156592d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZNF536 COL28A1 ZNF724 SASS6 GRIN2B

3.49e-061845654e3ba64692868563a579902aa9c6f88cab5bce26
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX COL28A1 GATA2 DOCK6 ITGB1

3.68e-061865650ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE2 ATRX ANKRD11 ITGB1 NSD3

4.52e-06194565e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellMesenchymal_cells-Stromal_fibro.|World / Lineage and Cell class

RARRES2 ADAMTS1 COL28A1 GRIN2B TPPP3

4.64e-0619556569723b06c2a5c2aaf4d10874b11bca7f06822bdc
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|368C / Donor, Lineage, Cell class and subclass (all cells)

SYTL3 ZNF184 RAP1GAP2 ZNF107

4.66e-05158564390b9c455ed15a6804613eecfd2776949dfba146
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-|Lung / Manually curated celltypes from each tissue

RARRES2 ADAMTS1 SYTL3 ADAM22

4.78e-05159564595643e9433265308e5aab7f906229025701cf6a
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 C6 KLKB1 UNC80

6.06e-0516956412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL3 ZNF184 NOC3L GATA2

6.34e-05171564ac37c80c832504986c7a201d84f4b6aff5e5f323
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL3 ZNF184 NOC3L GATA2

6.34e-05171564b6502a81df4f25660f3ae4b7443a1d999df2d32b
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELAPOR2 LRCH2 DOCK6 KLKB1

6.63e-0517356485083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF536 LRCH2 RARRES2 ADAMTS1

6.94e-051755641799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

RARRES2 ADAMTS4 ADAMTS1 GATA2

7.09e-05176564b288116a4588a1f9db9d49af92cea118937c9201
ToppCellASK454-Epithelial-Ciliated|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL28A1 CSNK1G1 C6 TPPP3

7.57e-05179564f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 ADAMTS1 SASS6 ITGB1

7.74e-0518056440d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL28A1 GATA2 CHEK2 DGKE

8.07e-0518256481279877b920b5a1bc991a07d3031d6458700fe3
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

ADAMTS4 ADAMTS1 ZNF727 TPPP3

8.25e-05183564a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GATA2 DGKE GRIN2B SKAP2

8.25e-05183564c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 LRCH2 RARRES2 ADAM22

8.25e-0518356412daaea821e49bc94a01e2496331e92a80d27339
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX ANKRD11 BAZ1B EP300

8.42e-051845641154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

ZNF536 LRCH2 RARRES2 ADAMTS1

8.42e-0518456486a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RARRES2 ADAMTS1 TPPP3 ITGB3

8.60e-05185564d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

RAB3GAP1 ATRX ZNF184 EP300

8.78e-0518656403db813598b67b1e08f759758a1c2023396921fa
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

ADAMTS4 ADAMTS1 GRIN2B DOCK6

8.96e-051875641e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX ADAMTS1 ANKRD11 TPPP3

9.15e-05188564d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellASK454-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL28A1 CSNK1G1 C6 TPPP3

9.53e-051905645cea6480f08253d7adf484e511d3fdfa96641268
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 DGKE ADAM22 UNC80

9.73e-05191564f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 ADAMTS1 TPPP3 ITGB1

1.05e-04195564eb2003d4f15cad213d17eda8ab7479f5a0c62164
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 ADAMTS1 TPPP3 ITGB1

1.05e-0419556444f67437ea65d530133a0240b17f9860d9cc0e99
ToppCellILEUM-non-inflamed-(8)_Pericytes|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RARRES2 ADAMTS4 ADAMTS1 TPPP3

1.07e-04196564b98fe1519e420d8b03c66e164bf4544f3dbb2e44
ToppCellILEUM-non-inflamed-(9)_Enteric_neurons|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZNF536 RARRES2 COL28A1 TPPP3

1.07e-04196564998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

ATRX SYTL3 ANKRD11 ITGB1

1.07e-041965647bced0cc2112697593c478fa291b8ed3941fb811
ToppCellILEUM-non-inflamed-(9)_Neuro_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZNF536 RARRES2 COL28A1 TPPP3

1.07e-041965642b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF536 ADAMTS4 DIPK1A TPPP3

1.10e-04197564032ccc91e604113da9bc34a6f9ddb1d45dea1892
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF560 ADAMTS4 ADAMTS1 GATA2

1.14e-04199564d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

RARRES2 ADAMTS4 ADAMTS1 ITGB1

1.14e-041995644d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

RARRES2 ADAMTS4 ADAMTS1 ITGB1

1.14e-0419956493e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

ATRX SYTL3 ZNF107 NSD3

1.14e-04199564952fac67588ad5676f5939e3c7f8bac803c27064
ToppCelldistal-mesenchymal-Pericyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RARRES2 ADAMTS4 ADAMTS1 TPPP3

1.14e-04199564e72ac7a00405cde06293d7adac7dc40eb0cf87ba
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SCUBE2 RARRES2 ADAMTS1 CHEK2

1.16e-042005649b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellBrain_organoid-organoid_Tanaka_cellReport|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

RARRES2 ADAMTS1 TPPP3 CBS

1.16e-04200564b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCelldistal-mesenchymal-Airway_Smooth_Muscle-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RARRES2 ADAMTS4 ADAMTS1 TPPP3

1.16e-04200564f09eaa52e11262ec47f3dcb4d890e240eaaa2b3d
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

RARRES2 ADAMTS1 ITGB1 ADAM22

1.16e-04200564a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

SCUBE2 RARRES2 ADAMTS1 CHEK2

1.16e-04200564a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCelldistal-1-mesenchymal-Pericyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RARRES2 ADAMTS4 ADAMTS1 TPPP3

1.16e-04200564ff205afda57b9267016f0c937445da1b0266af9b
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

RARRES2 ADAMTS1 GATA2 SKAP2

1.16e-04200564e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 GATA2 RAP1GAP2

4.74e-04121563da8fe561dcf50792d0cbcaad383d564f900a6677
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-myeloid_DC_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZNF560 RARRES2 ZNF727

5.21e-04125563baccea6889a829e05a9feac71b420f483a8107b4
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYTL3 GATA2 RAP1GAP2

6.24e-0413356381189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRCH2 ADAMTS4 ADAMTS1

6.38e-04134563bffd6ce8998368d4f486b64c220eab3a44ba147b
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYTL3 GATA2 RAP1GAP2

6.66e-0413656382d7f90ef2a63a3137c331efd68c036cd0db3ac1
ToppCellCOVID-19_Severe-Classical_Monocyte-|Classical_Monocyte / Disease condition and Cell class

ADAMTS1 DIPK1A ADAM22

6.66e-04136563e272d11bb52f890f6681cc9384aeac27976ec650
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYTL3 GATA2 RAP1GAP2

7.10e-04139563f1d1a51a79afdddc82e73cd29b3240e3e973db28
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYTL3 GATA2 RAP1GAP2

7.86e-04144563013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B TPPP3 UNC80

8.02e-0414556396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 KLKB1 CBS

9.02e-04151563cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 KLKB1 CBS

9.02e-041515637758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 KLKB1 CBS

9.02e-04151563b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF536 KIF24 ADAM22

9.19e-041525632741d266d65f6bc8c9134e7d713c20f573db1225
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 KLKB1 CBS

9.19e-041525631febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 KLKB1 CBS

9.19e-04152563faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF536 KIF24 ADAM22

9.19e-04152563e3f69aae3e6e3fca1d7727ae47817259473d5301
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DIPK1A RAP1GAP2 ADAM22

9.19e-041525630c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP2 TPPP3 PRDM15

9.37e-04153563e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

SYTL3 COL28A1 C6

9.91e-0415656310d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

GATA2 ZNF724 ZNF727

1.01e-03157563eb2520c237543ea4869d4386afc0457b111f6193
ToppCelldroplet-Liver-nan-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES2 KLKB1 CBS

1.01e-03157563b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

RAP1GAP2 GRIN2B UNC80

1.03e-031585631f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellBac-SEP-Lymphocyte-T_NK-CD4_CTL|Bac-SEP / Disease, Lineage and Cell Type

SYTL3 ZNF737 ITGB1

1.03e-031585634beed58bf58253253fc7e5009294b35e3bb8eae3
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA2 CHEK2 KIF24

1.07e-031605639f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA2 CHEK2 KIF24

1.07e-031605633b3b99305558f5b49d050fb9b249007630ea9085
ToppCellfacs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF184 DGKE DOCK6

1.07e-03160563b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ELAPOR2 LRCH2 ADAMTS4

1.08e-03161563fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ELAPOR2 LRCH2 ADAMTS4

1.08e-03161563c53c461fc721a7960cef86662f49e2a495520701
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 COL28A1 GRIN2B

1.10e-03162563d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 COL28A1 GRIN2B

1.10e-031625635bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 COL28A1 GRIN2B

1.10e-03162563eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ELAPOR2 LRCH2 ADAMTS4

1.10e-031625632ac02523348660e514d464f8f2434ee0c312d784
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 COL28A1 GRIN2B

1.10e-03162563e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAP1GAP2 PRDM15 KIF24

1.12e-031635637af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellnormal-na-Lymphocytic_T-T4_reg-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ATRX ITGB1 NSD3

1.12e-0316356343887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF536 COL28A1 UNC80

1.14e-031645633caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCellIonocyte|World / shred by cell class for turbinate

SCUBE2 RARRES2 ITGB3

1.16e-031655630cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETDB2 NOC3L CHEK2

1.18e-031665635c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL3 GATA2 UNC80

1.18e-03166563c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL3 GATA2 UNC80

1.18e-031665630975fc165bcc7e85f053d9d0244fffe407c23571
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SCUBE2 RARRES2 DOCK6

1.18e-031665636d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 LY75 ITGB3

1.21e-03167563b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS4 TRAPPC8 PRDM15

1.21e-03167563a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellCiliated_cells-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

ZNF536 RARRES2 C6

1.21e-03167563edb722ee9b6ccd00fb038f702be8664020932659
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIPK1A TPPP3 ITGB3

1.23e-03168563f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCellBAL-Control-cDC_6|Control / Compartment, Disease Groups and Clusters

SYTL3 ZFP64 DOCK6

1.23e-0316856365ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

RARRES2 ADAMTS1 ITGB3

1.23e-031685638c95093b1ea45826f62893edd3c410fe53b563a4
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF878 SYTL3 ITGB1

1.23e-03168563b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCelldroplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP2 TPPP3 UNC80

1.23e-03168563ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 COL28A1 RAP1GAP2

1.23e-0316856395dc690c1987b05685d36e6bb20eb79308696e30
ToppCelldroplet-Liver-Npc-18m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP2 TPPP3 UNC80

1.23e-0316856322c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

RARRES2 ADAMTS1 ITGB3

1.23e-03168563b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCUBE2 TPPP3 KLKB1

1.23e-03168563435ef2e4d702e978d54f9d1f5a047f39c691cc63
Diseaseglomerulonephritis (is_marker_for)

ITGB3 KLKB1 EP300

5.20e-0619533DOID:2921 (is_marker_for)
DiseaseAutism Spectrum Disorders

ANKRD11 GRIN2B ITGB3 UNC80

1.69e-0585534C1510586
DiseaseInternal Carotid Artery Thrombosis

ITGB3 KLKB1

1.89e-054532C0750990
DiseaseCommon Carotid Artery Thrombosis

ITGB3 KLKB1

1.89e-054532C0750988
DiseaseExternal Carotid Artery Thrombosis

ITGB3 KLKB1

1.89e-054532C0750989
DiseaseCarotid Artery Thrombosis

ITGB3 KLKB1

1.89e-054532C0007274
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2B CBS

1.72e-0411532DOID:9279 (implicated_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ADAMTS4 ADAMTS1 ITGB3 EP300

1.84e-04157534DOID:224 (biomarker_via_orthology)
Diseasemyeloid leukemia (is_implicated_in)

GATA2 NSD3

2.44e-0413532DOID:8692 (is_implicated_in)
Diseaselung small cell carcinoma (is_marker_for)

ATRX ITGB1

3.74e-0416532DOID:5409 (is_marker_for)
DiseaseAstrocytosis

ITGB1 ITGB3

4.23e-0417532C3887640
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

PRDM15 KLKB1

4.23e-0417532EFO_0008011
DiseaseGliosis

ITGB1 ITGB3

4.23e-0417532C0017639
DiseaseTourette syndrome, schizophrenia

ZNF536 NSD3

4.75e-0418532EFO_0004895, MONDO_0005090
Diseasemyelodysplastic syndrome (is_marker_for)

GATA2 ITGB3

5.89e-0420532DOID:0050908 (is_marker_for)
Diseaseglomerulonephritis (biomarker_via_orthology)

ITGB1 ITGB3

5.89e-0420532DOID:2921 (biomarker_via_orthology)
DiseaseLow Grade Lymphoma (neoplasm)

CHEK2 CBS

6.50e-0421532C0079747
DiseaseLymphoma, Intermediate-Grade

CHEK2 CBS

6.50e-0421532C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

CHEK2 CBS

6.50e-0421532C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

CHEK2 CBS

6.50e-0421532C0079757
DiseaseLymphoma, Undifferentiated

CHEK2 CBS

6.50e-0421532C0024306
DiseaseReticulosarcoma

CHEK2 CBS

6.50e-0421532C0024302
DiseaseLymphoma, Mixed-Cell

CHEK2 CBS

6.50e-0421532C0024304
DiseaseLymphoma, Diffuse

CHEK2 CBS

6.50e-0421532C3714542
DiseaseLymphoma, Non-Hodgkin, Familial

CHEK2 CBS

7.15e-0422532C4721532
DiseaseLymphoma, Small Noncleaved-Cell

CHEK2 CBS

7.15e-0422532C0079770
DiseaseHematopoetic Myelodysplasia

ATRX GATA2

1.25e-0329532C2713368
DiseaseLymphoma, Non-Hodgkin

CHEK2 CBS

1.52e-0332532C0024305
Diseaseclear cell renal cell carcinoma (is_marker_for)

GATA2 EP300

1.61e-0333532DOID:4467 (is_marker_for)
Diseaseplasma betaine measurement

LY75 CBS

1.71e-0334532EFO_0007787

Protein segments in the cluster

PeptideGeneStartEntry
VCDGCLKKSARTRKE

EP300

1271

Q09472
CQKDKEFDKCFKEKK

ANKRD11

1046

Q6UB99
RKKGEDDKLILCDEC

BAZ1B

1191

Q9UIG0
ISDKRKLASGECKCE

ADAM22

381

Q9P0K1
CGEVKLAFERKTCKK

CHEK2

231

O96017
NCCIERKKARDEGKK

RAB3GAP1

521

Q15042
RKCLACIKLGSEDKV

RARRES2

96

Q99969
CVKAGCDRIIDSKKK

ADAMTS1

696

Q9UHI8
CDRIIDSKKKFDKCG

ADAMTS1

701

Q9UHI8
SARCDDLEALKKKGC

ITGB1

61

P05556
VEEAKCCCFFKRKRK

CSNK1G1

401

Q9HCP0
DRVKELKKGIKCCTS

KIF24

541

Q5T7B8
SCEEKLKYVCKRKGE

LY75

476

O60449
SEKGAKECIRCKDDS

ELAPOR2

316

A8MWY0
INEKDRCKKCEGKKV

DNAJA2

196

O60884
KSKKGAECFEELSKC

GATA2

406

P23769
DAKFETKARKGEKPC

ATRX

436

P46100
GCDRIIGSKKKFDKC

ADAMTS4

661

O75173
FEKKCERKICECEKG

COL28A1

231

Q2UY09
DFCKKCEDALRKNKA

DOCK6

1976

Q96HP0
KLCKIEEADCKNKFR

C6

131

P13671
GKKFGLKCELLAKCE

CBS

96

P35520
PDACTFKKECVECKK

ITGB3

631

P05106
FKKECVECKKFDRGA

ITGB3

636

P05106
KEEKCKCFLRLSMDG

KLKB1

341

P03952
EGCLRKADKRFQCKE

DGKE

96

P52429
RKSCKEIERKKEKCG

DEFB115

46

Q30KQ5
EIERKKEKCGEKHIC

DEFB115

51

Q30KQ5
TELCRGKDCKKIICD

DIPK1A

51

Q5T7M9
DCGCKKGFKLLTDEK

SCUBE2

346

Q9NQ36
KFLAGCLKCSKEEKL

SASS6

151

Q6UVJ0
FKGKEKCSEKSRKNE

LRCH2

431

Q5VUJ6
CCEAVKKLFKQDKLG

NOC3L

381

Q8WTT2
CIKACKNLAYGEEKK

SYTL3

326

Q4VX76
NACCKSDKFAKLEDR

RAP1GAP2

441

Q684P5
TLRKDGKKDCCFEIS

SKAP2

176

O75563
GDKLFKCEECAKLFS

PRDM15

761

P57071
KCEECAKLFSRKESL

PRDM15

766

P57071
KKKCCFVALDPIEEK

ACTL7A

276

Q9Y615
KCEECGKACKKFSNL

ZNF727

201

A8MUV8
KCEECDKAFNRSLKL

ZNF107

301

Q9UII5
FSKKRKLEVACSDCE

SETDB2

426

Q96T68
KCKECGKAFKRSSNL

ZNF724

451

A8MTY0
LRGKKQKECSDKSCL

UNC80

1521

Q8N2C7
DRGEKKLLKCNDCEK

ZNF470

221

Q6ECI4
KKLFECKECGKSFNR

ZNF780B

246

Q9Y6R6
SASKKKCEKGGRLLC

NSD3

911

Q9BZ95
AKLCKDCKVADGKSV

TPPP3

36

Q9BW30
CTFCKGKFKKREELD

ZNF536

276

O15090
ECKECGKAFSNRKDL

ZNF264

456

O43296
REKGKFCFKAIRCEK

TRAPPC8

1151

Q9Y2L5
KCEECGKAFKQSSKL

ZNF355P

101

Q9NSJ1
CKECEKAFRSGSKLI

ZNF345

316

Q14585
KCEVCGKCFSRKDKL

ZFP64

176

Q9NTW7
EKLFKCSDCGKVFLK

ZNF584

156

Q8IVC4
VKKEKSCKCNECGKA

ZNF184

216

Q99676
ECKKCGKAFTERSDL

ZNF560

601

Q96MR9
CKKCVKAFSFVKDLR

ZNF878

341

C9JN71
KCEECGKAFKRSSIL

ZNF737

286

O75373
CCKGFCIDILKKISK

GRIN2B

456

Q13224