Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF20A NPHS1 SPATA31A1 SPATA31A3 STARD9 SPATA31A7 ARPC1A CGN OBSCN MTCL1 CORO7 SPATA31A6 SPATA31A5 ARPC1B SNTB1

4.75e-0710995915GO:0008092
GeneOntologyMolecularFunctionactin binding

SPATA31A1 SPATA31A3 SPATA31A7 ARPC1A CGN CORO7 SPATA31A6 SPATA31A5 ARPC1B SNTB1

1.26e-064795910GO:0003779
GeneOntologyMolecularFunctionhistone acetyltransferase activity

METTL8 JADE1 GTF3C4

4.61e-0451593GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

METTL8 JADE1 GTF3C4

5.76e-0455593GO:0061733
GeneOntologyMolecularFunctionRNA polymerase III general transcription initiation factor activity

SNAPC4 GTF3C4

6.56e-0413592GO:0000995
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

METTL8 JADE1 GTF3C4

7.44e-0460593GO:0034212
GeneOntologyMolecularFunctionintermediate filament binding

PKP2 FAM83H

8.79e-0415592GO:0019215
GeneOntologyMolecularFunctionN-acetyltransferase activity

METTL8 JADE1 GTF3C4

1.59e-0378593GO:0008080
GeneOntologyCellularComponentacrosomal vesicle

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

2.88e-04206595GO:0001669
GeneOntologyCellularComponentArp2/3 protein complex

ARPC1A ARPC1B

3.47e-0410592GO:0005885
GeneOntologyCellularComponentanchoring junction

CASS4 NPHS1 HEG1 CGN OBSCN PKP2 ILDR1 ARPC1B SNTB1 WNK4

3.68e-049765910GO:0070161
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

3.79e-0812574PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

3.79e-0812574IPR027970
DomainARPC1

ARPC1A ARPC1B

9.15e-062572IPR017383
DomainDUF3699

GARIN4 TASOR2

3.25e-049572PF12480
DomainDUF3699

GARIN4 TASOR2

3.25e-049572IPR022168
DomainFN3_dom

IL10RA NPHS1 SNED1 PTPRB OBSCN

4.37e-04209575IPR003961
DomainSEA

MUC16 MUC3A

8.13e-0414572SM00200
Domain-

IL10RA NPHS1 SNED1 PTPRB TAPBPL OBSCN ILDR1 CADM2

8.59e-046635782.60.40.10
DomainIg-like_fold

IL10RA NPHS1 SNED1 PTPRB TAPBPL OBSCN ILDR1 CADM2

1.29e-03706578IPR013783
Domainfn3

NPHS1 SNED1 PTPRB OBSCN

1.51e-03162574PF00041
DomainSEA

MUC16 MUC3A

2.22e-0323572PS50024
DomainSEA_dom

MUC16 MUC3A

2.22e-0323572IPR000082
DomainFN3

NPHS1 SNED1 PTPRB OBSCN

2.44e-03185574SM00060
DomainSAM

ANKS6 SAMD10 ANKS1B

2.46e-0388573SM00454
DomainSAM_DOMAIN

ANKS6 SAMD10 ANKS1B

3.06e-0395573PS50105
DomainFN3

NPHS1 SNED1 PTPRB OBSCN

3.18e-03199574PS50853
DomainIg_V-set

NPHS1 TAPBPL OBSCN CADM2

3.18e-03199574IPR013106
DomainSAM

ANKS6 SAMD10 ANKS1B

3.24e-0397573IPR001660
Domain-

ANKS6 SAMD10 ANKS1B

4.16e-031065731.10.150.50
DomainSAM/pointed

ANKS6 SAMD10 ANKS1B

5.48e-03117573IPR013761
DomainC2-set_2

NPHS1 CADM2

6.95e-0341572PF08205
DomainKinesin_motor_CS

KIF20A STARD9

6.95e-0341572IPR019821
DomainCD80_C2-set

NPHS1 CADM2

6.95e-0341572IPR013162
DomainKINESIN_MOTOR_1

KIF20A STARD9

7.97e-0344572PS00411
Domain-

KIF20A STARD9

7.97e-03445723.40.850.10
DomainKinesin_motor_dom

KIF20A STARD9

7.97e-0344572IPR001752
DomainKinesin

KIF20A STARD9

7.97e-0344572PF00225
DomainKISc

KIF20A STARD9

7.97e-0344572SM00129
DomainKINESIN_MOTOR_2

KIF20A STARD9

7.97e-0344572PS50067
DomainIG

NPHS1 TAPBPL OBSCN ILDR1 CADM2

9.10e-03421575SM00409
DomainIg_sub

NPHS1 TAPBPL OBSCN ILDR1 CADM2

9.10e-03421575IPR003599
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAC_TO_ACTIN_SIGNALING_PATHWAY

ARPC1A ARPC1B

4.86e-0413362M47723
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_CDC42_SIGNALING_PATHWAY

ARPC1A ARPC1B

4.86e-0413362M47730
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TCCP_TO_ACTIN_SIGNALING_PATHWAY

ARPC1A ARPC1B

5.66e-0414362M47729
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPT_TO_RAC_SIGNALING_PATHWAY

ARPC1A ARPC1B

5.66e-0414362M47726
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC3A

7.44e-0416362M27410
PathwayKEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY

ARPC1A ARPC1B

8.42e-0417362M47728
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC3A

8.42e-0417362M27412
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

8.41e-14661520850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

8.41e-14661525930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

5.81e-102461532212159
Pubmed

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.

ARPC1A CGN ARPC1B

8.39e-054861327872092
Pubmed

The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

ARPC1A ARPC1B

8.42e-0586129230079
Pubmed

Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins.

ARPC1A ARPC1B

8.42e-0586129359840
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EXPH5 STARD9 CGN MAP3K14 PKP2 MTCL1 WNK4 FAM83H

1.26e-0486161836931259
Pubmed

Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion.

ARPC1A ARPC1B

1.35e-041061212473693
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

PTPRB EXPH5 OBSCN SPATA31A6 GTF3C4 WNK4

2.36e-0449761636774506
Pubmed

A whole genome association study of mother-to-child transmission of HIV in Malawi.

DDR1 GTF3C4

2.72e-041461220487506
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EXPH5 ARPC1A CGN PKP2 PCBP1 ARPC1B GTF3C4 FAM83H TASOR2

3.27e-04125761936526897
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC3A

4.55e-041861218834073
Pubmed

DNA sequence and analysis of human chromosome 9.

ZDHHC12 ANKS6 SPATA31A1 SPATA31A7 SNAPC4

4.84e-0437061515164053
Pubmed

p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells.

SPATA31A3 MUC3A

6.83e-042261225331947
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CGN PKP2 MTCL1 SNTB1 GTF3C4

1.12e-0344661524255178
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

PKP2 MTCL1 SNTB1

1.40e-0312561329467281
Cytoband1q42.13

MRPL55 OBSCN OBSCN-AS1

3.94e-05496131q42.13
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

4.84e-058612chr9q12
Cytoband9p13.1

SPATA31A1 SPATA31A3

4.70e-04246129p13.1
GeneFamilyActin related protein 2/3 complex

ARPC1A ARPC1B

1.70e-04940239
GeneFamilyFibronectin type III domain containing

NPHS1 SNED1 PTPRB OBSCN

4.21e-04160404555
GeneFamilySterile alpha motif domain containing

ANKS6 SAMD10 ANKS1B

9.66e-0488403760
GeneFamilyCD molecules|Mucins

MUC16 MUC3A

9.76e-0421402648
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

NPHS1 CADM2

3.53e-0340402592
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF20A STARD9

4.64e-0346402622
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB NHSL2 STARD9

4.56e-06178615375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HEG1 PTPRB NHSL2 ARPC1B SNTB1

5.94e-0618861550b27fc12347ca16bd62333baf345c83cb422a8f
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

GARIN4 SAMD10 PLEKHF1 GZMA

3.75e-05137614885e4cfc237eca1fa2eb1f2fd8d84f151e21ecfa
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKS6 STARD9 MAP3K14 MUC16

5.34e-051506147a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

CGN ANKS1B PKP2 MUC16

6.22e-05156614e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DDR1 EXPH5 ILDR1 FAM83H

6.54e-0515861498712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellCOVID-19_Severe-PLT_3|World / Disease Group and Platelet Clusters

CACNA1F ARPC1B FAM83H ZNF114

6.54e-05158614b981592129cd00564a7e44e6ed43fef4585f4700
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHF1 GZMA TMEM63C ZNF114

6.86e-05160614ab633295cb4de88fdbc076295e1352769f47cc00
ToppCellHealthy_Control-Lymphoid-T-innate_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SAMD10 PLEKHF1 GZMA MTCL1

7.73e-051656141ade67229b50fe20eb392262a3e1ee4306b73290
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 CGN PKP2 MTCL1

7.92e-0516661411b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellICU-NoSEP-Lymphocyte-T_NK-MAIT|ICU-NoSEP / Disease, Lineage and Cell Type

CASS4 SLC6A16 ANKS1B TMEM63C

7.92e-05166614d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 CGN PKP2 MTCL1

7.92e-05166614fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

STARD9 ARPC1A GZMA CGN

8.10e-05167614cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HEG1 PTPRB JADE1 WNK4

8.68e-0517061455fe16d98ea284d05fb899888e4569c685644c7b
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IL10RA DDR1 ANKS1B ZNF692

9.08e-05172614d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OBSCN TMEM63C MUC16 MUC3A

9.50e-05174614207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ANKS6 EXPH5 CGN MUC16

9.71e-05175614e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDR1 CGN PKP2 MTCL1

1.04e-04178614a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDR1 CGN PKP2 MTCL1

1.04e-04178614b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GARIN4 EXPH5 CGN WNK4

1.06e-04179614c833ded1f9e87be2ba2037820d92a389560b711c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CASS4 TAPBPL MRPL55 SPATA31A7

1.08e-0418061481d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 NHSL2 EXPH5 ZNF692

1.08e-04180614d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HEG1 PTPRB NHSL2 ARPC1B

1.13e-04182614345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.18e-04184614688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASS4 IL10RA PLEKHF1 GZMA

1.23e-04186614e083356f72995645f873ca0157d56bea5e942044
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ILDR1 WNK4 RNF182 CADM2

1.23e-041866148eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DDR1 CGN PKP2 CLBA1

1.23e-04186614521e6e007bbae73e7328153aa170cf04ca3c1093
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

KIF20A HEG1 GZMA GTF3C4

1.23e-041866145cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SAMD10 EXPH5 CGN PKP2

1.25e-04187614baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.25e-0418761435c382c0aabd46906113e5db30ea24bb8e658899
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CGN PKP2 ILDR1 CLBA1

1.25e-04187614a4b41904ba05eb76212c949fc3ac197f906c8351
ToppCellE12.5-Epithelial-alveolar_epithelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SAMD10 EXPH5 CGN PKP2

1.28e-04188614c19c89756f2f999e0814f08a89818ef156f6fc69
ToppCellnormal_Pleural_Fluid-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

IL10RA ANKS1B METTL8 ARPC1B

1.33e-04190614519356c4925b5b6647e7d763d4084cd9b2e94f0a
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 EXPH5 ILDR1 WNK4

1.33e-04190614c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 EXPH5 ILDR1 WNK4

1.33e-04190614d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-Cycling_NK|lymph-node_spleen / Manually curated celltypes from each tissue

KIF20A PTPRB GZMA CHRM5

1.33e-04190614451eaceb0cb0ec6cfcae00253c0e5c92a168c2f3
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

SNED1 STARD9 ANKS1B JADE1

1.36e-0419161470c067c54084bfb02c29bab085f4defd477194fb
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Treg|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA ANKS1B METTL8 ARPC1B

1.39e-04192614b7e08cadb50f66c2efdde45e0fa8bab29367269b
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 EXPH5 ILDR1 WNK4

1.39e-041926146fb56d062c35617b18b927704bf5fba894faed81
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDR1 EXPH5 CGN PKP2

1.39e-04192614790282d4232311df3dac4ad97c80fc53443beccc
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDR1 EXPH5 CGN PKP2

1.39e-04192614b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.39e-04192614c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 EXPH5 ILDR1 WNK4

1.41e-04193614536b277d90070c4571c592a3c6323b4bf4819f67
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

SNED1 HEG1 PTPRB NHSL2

1.41e-0419361401c2df9206f1527c578e808978e58196c35e72f5
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 EXPH5 ILDR1 WNK4

1.41e-04193614fa8bcf2a5ab7b08fae98a1466a936995142b4309
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF20A ZDHHC12 EXPH5 CGN

1.44e-04194614c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.44e-04194614f76808666fb875fc787751cbfd924d9be20a8192
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA PLEKHF1 GZMA ARPC1B

1.44e-04194614eaa5914009556af99eba80e1925db5c95d3a5b5d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.44e-04194614f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.44e-04194614a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

CASS4 NHSL2 RNF182 CADM2

1.47e-0419561461c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.50e-041966148ad8efb631164b46f0c082572270188e5ead20bf
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

DDR1 EXPH5 CGN PKP2

1.50e-04196614484bbc6b1f58bc260964babb949d14f5df101393
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.50e-04196614ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDR1 EXPH5 CGN PKP2

1.50e-041966149790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDR1 EXPH5 CGN PKP2

1.50e-04196614b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.50e-041966149606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.53e-04197614cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.53e-041976140f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.53e-04197614412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellBL-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DDR1 EXPH5 CGN MUC16

1.56e-041986146218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NPHS1 DDR1 MUC16 CADM2

1.56e-04198614dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

HEG1 PTPRB NHSL2 STARD9

1.56e-041986148689090bce9ab6e8f122426a404037e572c6713b
ToppCell(2)_NK/T-(23)_CD4+_T_cell-(231)_CD4+/CD45RO+_Memory_T_cell|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)

IL10RA GZMA CORO7 ARPC1B

1.56e-04198614cd1548fc27779ada721ca00c72ebd3b6c9b15a19
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 HEG1 PTPRB STARD9

1.56e-041986140a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell(07)_Ionocytes|World / shred by cell type by condition

MUC16 JADE1 SNTB1 CADM2

1.59e-041996148194777d367405a7840787e977854b5c07e3bd6b
ToppCelltumor_Lung-Epithelial_cells-tS2|tumor_Lung / Location, Cell class and cell subclass

DDR1 ARPC1A MUC16 FAM83H

1.59e-0419961428ec59e01061287fb0892491790b316e2b93e232
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

EXPH5 OBSCN MUC3A

1.61e-0477613a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DDR1 EXPH5 CGN MUC16

1.62e-04200614d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DDR1 EXPH5 CGN MUC16

1.62e-04200614d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma|TCGA-Endometrium / Sample_Type by Project: Shred V9

KIF20A ZDHHC12 SAMD10 FAM83H

1.62e-04200614e3ad8d592686a5d1e1fb8dd05c2f00eac4c5738f
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DDR1 EXPH5 CGN MUC16

1.62e-042006140cc7ff7b6a4eb05d2370ec2f3b9dbfe8cb0699de
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DDR1 EXPH5 CGN MUC16

1.62e-04200614b9cede2e0939c6b60ce1aa16d7efaaae79354580
ToppCellTCGA-Endometrium-Primary_Tumor|TCGA-Endometrium / Sample_Type by Project: Shred V9

KIF20A ZDHHC12 SAMD10 FAM83H

1.62e-042006141cbb62df4ea1631fef8497e1702175605d0869e7
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DDR1 EXPH5 CGN MUC16

1.62e-04200614b762bf6f432eac05a476f6e2ab4da27dd13a2317
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DDR1 EXPH5 CGN MUC16

1.62e-042006144c63204e0d868dd4c11c1604a238624a3ad54485
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DDR1 EXPH5 CGN MUC16

1.62e-04200614ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellSevere_COVID-19-Epithelial|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DDR1 EXPH5 CGN MUC16

1.62e-0420061449910efb6d888c208cd50530b03af19f87070630
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-MAIT|ICU-NoSEP / Disease, condition lineage and cell class

CASS4 SLC6A16 ANKS1B TMEM63C

1.62e-042006144f03b5f4110ed1637ffe17cb6ff309265a3af9a8
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Lypd1_(CA1_Principal_cells_(Anterior))|Hippocampus / BrainAtlas - Mouse McCarroll V32

NPHS1 CACNA1F CHRM5

2.09e-048461352d167614afa9b056f2934142d3250fe5e70e806
Diseaseosteosarcoma (is_marker_for)

DDR1 PTPRB

1.79e-0411542DOID:3347 (is_marker_for)
Diseaseproteinuria (implicated_via_orthology)

NPHS1 ANKS6

1.38e-0330542DOID:576 (implicated_via_orthology)
Diseasecutaneous melanoma

RTEL1 CORO7 TASOR2

1.43e-03121543EFO_0000389
DiseaseOvarian Mucinous Adenocarcinoma

MAP3K14 WNK4

1.48e-0331542C1335167
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1F SNTB1

1.99e-0336542DOID:11723 (implicated_via_orthology)
Diseasebipolar I disorder

STARD9 ANKS1B CADM2

2.22e-03141543EFO_0009963
Diseaseasthma

ZDHHC12 RTEL1 MAP3K14 MUC16 ILDR1 SNTB1

2.44e-03751546MONDO_0004979
Diseaseheart rate response to exercise

PLEKHF1 MUC3A

2.83e-0343542EFO_0009184
DiseaseProteinuria

NPHS1 MUC16

2.83e-0343542C0033687
Diseaseschizophrenia (is_marker_for)

ARPC1A ARPC1B

2.96e-0344542DOID:5419 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
SAGHNSSWFSRRTTS

CASS4

376

Q9NQ75
LEAESFHSTTWSRIR

AKAP10

156

O43572
SASGSRVAWVSHDST

ARPC1B

211

O15143
SSWSDSTAARHSRLE

DDR1

51

Q08345
THNSASWSDTLREVN

GZMA

156

P12544
AQSTTWQTRNHTRTG

CIRBP-AS1

66

Q8TBR5
GSRLAWVSHDSTVSV

ARPC1A

216

Q92747
SAWARSTTTRESPVH

MTCL1

1741

Q9Y4B5
TSRVNWSESSTAEHS

ANKS1B

751

Q7Z6G8
LRWFSHSTRSTHSTS

CACNA1F

451

O60840
ESVTSRTSYNHRSWI

MUC16

12016

Q8WXI7
STAWGTEHTQAVARS

NPHS1

286

O60500
TLRNRSTEDLHVTWS

PTPRB

826

P23467
WASLDASTQTTHELT

PCBP1

271

Q15365
ESRTSHKSGRSLWTT

GARIN4

501

Q8IYT1
ATWKDTEHSRNSSAS

C9orf131

541

Q5VYM1
STQAHENSRDSRLAW

CORO7

206

P57737
WSSHFARTTIVNVST

TMEM63C

166

Q9P1W3
FTSLITTTETTSHRW

MUC3A

2161

Q02505
ESSSNEVPWTRRSTH

FAM221B

131

A6H8Z2
SSRRTSDSLHQQWLT

ILDR1

341

Q86SU0
SRIITNNHWSSALTD

EXPH5

841

Q8NEV8
SRHSNWTVTNTRFSV

IL10RA

106

Q13651
AHWLLTNSTTSADVT

HEG1

456

Q9ULI3
VVARSSHTVTLSWAA

OBSCN

4531

Q5VST9
RASWHELSISVSDVS

CADM2

81

Q8N3J6
SFELWSSDRSRTRHN

ANKS6

566

Q68DC2
TVASHSKAVVSQAWR

FAM83H

756

Q6ZRV2
RESSWDHVKTSATNR

METTL8

126

Q9H825
RDTLSSGVHSWSSQA

MAP3K14

821

Q99558
SGVHSWSSQAEARSS

MAP3K14

826

Q99558
WGTSHRNVADSFSRT

OBSCN-AS1

46

Q96MR7
VSAASATERQEWISH

PLEKHF1

111

Q96S99
HRRTAQRSDAWSTTA

RTEL1

431

Q9NZ71
ETSRDLSHWTRSIVQ

SNTB1

416

Q13884
SATSWTSEAQVSAAR

SLC6A16

41

Q9GZN6
ERWETTSCADTQSSH

TAPBPL

441

Q9BX59
ENATATAHSRSSWRQ

NHSL2

101

Q5HYW2
HVSASSRWQETARTS

SPATA31A6

276

Q5VVP1
HVSASSRWQETARTS

SPATA31A7

276

Q8IWB4
TSLTWHDSRSQRAAS

SAMD10

61

Q9BYL1
ASFDSVTTVSHNWTV

RNF182

156

Q8N6D2
GSRRHWSSTDISFAQ

STARD9

3646

Q9P2P6
TTWSQNSRSQHRRSS

JADE1

21

Q6IE81
TAARVTATSAHVVWD

SNED1

1111

Q8TER0
RNQASWSSSRRSTST

CHRM5

266

P08912
ERERQSTNHWTSSTK

CGN

226

Q9P2M7
QSIHTTSTSQRLWSE

CLBA1

201

Q96F83
HVSASSRWQETARTS

SPATA31A3

276

Q5VYP0
TSSFRRHSWSSVAFN

RHD

66

Q02161
HVSASSRWQETARTS

SPATA31A1

276

Q5TZJ5
HVSASSRWQETARTS

SPATA31A5

276

Q5VU36
LHTSSWRADSSRASL

MRPL55

26

Q7Z7F7
TSSSQLDETSHRWAQ

KIF20A

271

O95235
AWSEDHRVSVSTARS

GTF3C4

71

Q9UKN8
RARHSVRWSSTSSSG

SNAPC4

511

Q5SXM2
SSLDSSSSWRERCSH

TASOR2

2061

Q5VWN6
ASNTTTWEFISSHRI

ZDHHC12

206

Q96GR4
TQNRASRSSWHQSSF

PKP2

281

Q99959
SRSSWHQSSFHSTRT

PKP2

286

Q99959
SLEHRSWTAFSTSSS

WNK4

791

Q96J92
HTTRRSWCSEATSGQ

ZNF692

141

Q9BU19
THTYSVRWSETSVER

TM9SF1

201

O15321
LTSISSQHSTLREDW

ZNF114

76

Q8NC26