Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of centriole replication	KAT2B BRCA1	7.78e-05	8	35	2	GO:0046600
GeneOntologyBiologicalProcess	mucociliary clearance	CFAP54 CFAP43	2.16e-04	13	35	2	GO:0120197
GeneOntologyBiologicalProcess	negative regulation of centrosome cycle	KAT2B BRCA1	2.16e-04	13	35	2	GO:0046606
GeneOntologyBiologicalProcess	negative regulation of centrosome duplication	KAT2B BRCA1	2.16e-04	13	35	2	GO:0010826
GeneOntologyCellularComponent	eukaryotic 43S preinitiation complex	EIF1 EIF1B	5.11e-04	19	37	2	GO:0016282
GeneOntologyCellularComponent	translation preinitiation complex	EIF1 EIF1B	5.68e-04	20	37	2	GO:0070993
Domain	SUI1_euk	EIF1 EIF1B	3.61e-06	2	36	2	IPR005874
Domain	-	EIF1 EIF1B	2.16e-05	4	36	2	3.30.780.10
Domain	SUI1	EIF1 EIF1B	2.16e-05	4	36	2	PF01253
Domain	SUI1	EIF1 EIF1B	2.16e-05	4	36	2	PS50296
Domain	SUI1	EIF1 EIF1B	3.60e-05	5	36	2	IPR001950
Domain	TRASH_dom	ZMYM1 RSL24D1	1.00e-04	8	36	2	IPR011017
Domain	TRASH	ZMYM1 RSL24D1	1.00e-04	8	36	2	SM00746
Domain	FH2	FMN2 INF2	3.73e-04	15	36	2	PS51444
Domain	FH2_Formin	FMN2 INF2	3.73e-04	15	36	2	IPR015425
Domain	FH2	FMN2 INF2	3.73e-04	15	36	2	PF02181
Domain	FH2	FMN2 INF2	3.73e-04	15	36	2	SM00498
Domain	DEP_dom	FMN2 DEPDC7	8.91e-04	23	36	2	IPR000591
Pubmed	Coordination of microtubule acetylation and the actin cytoskeleton by formins.	FMN2 INF2	1.10e-06	2	37	2	29947928
Pubmed	Expressed sequence tags identify a human isolog of the suil translation initiation factor.	EIF1 EIF1B	1.10e-06	2	37	2	7904817
Pubmed	Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.	BRCA1 ABCB1	3.30e-06	3	37	2	23103855
Pubmed	Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.	BRCA1 ABCB1	6.60e-06	4	37	2	22767648
Pubmed	Involvement of MyoD and c-myb in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene.	KAT2B BRCA1	1.10e-05	5	37	2	20364308
Pubmed	Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.	BRCA1 ABCB1	1.65e-05	6	37	2	26100884
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RLF SRRM1 SGO2 KAT2B MED19 BRCA1	5.66e-05	645	37	6	25281560
Pubmed	BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin.	BRCA1 ABCB1	6.02e-05	11	37	2	20331623
Pubmed	SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.	SRRM1 INF2	7.22e-05	12	37	2	31911863
Pubmed	Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23.	BRCA1 ABCB1	8.53e-05	13	37	2	10433968
Pubmed	DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response.	BRCA1 ABCB1	9.94e-05	14	37	2	20338046
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMN2 INF2	9.94e-05	14	37	2	26272686
Pubmed	Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal women.	BRCA1 ABCB1	9.94e-05	14	37	2	19672706
Pubmed	SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.	SRRM1 INF2	1.67e-04	18	37	2	29996942
Pubmed	Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women.	KAT2B BRCA1	2.99e-04	24	37	2	19950226
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RLF SRRM1 SGO2 ZNF770 BRCA1	4.41e-04	608	37	5	36089195
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	SGO2 BRCA1 KIAA1217	5.07e-04	146	37	3	23892456
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	RLF SRRM1 KAT2B EIF1B ABCB1 COPB2	5.17e-04	971	37	6	33306668
Pubmed	Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.	SRRM1 INF2	8.37e-04	40	37	2	28805822
Pubmed	FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.	OR6B3 ABCB1	9.23e-04	42	37	2	29348145
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FMN2 MAGEB6 FBXO10 VPS13C COPB2	1.04e-03	736	37	5	29676528
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF770 GTF3A ZNF197	7.19e-03	718	20	4	28
ToppCell	Healthy/Control-MAIT\|Healthy/Control / Disease group and Cell class	KIAA1210 EIF1 KIAA1217 ABCB1	1.26e-05	173	37	4	56247c1e07477a8922fe2e3950ae05e2217fd77c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 CFAP43 FAM81B UGT2A3	1.32e-05	175	37	4	284fdc7a9d303636a637041846850d19d114861a
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FMN2 CFAP54 CFAP43 FAM81B	1.38e-05	177	37	4	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	IIF-Lymphocyte-T_NK-MAIT\|IIF / Disease, Lineage and Cell Type	GTF3A EIF1 KIAA1217 ABCB1	1.41e-05	178	37	4	be777ebef8f09a1a16fcee8fc69a65ab295b6e1d
ToppCell	Healthy_donor-MAIT\|Healthy_donor / disease group, cell group and cell class (v2)	KIAA1210 EIF1 KIAA1217 ABCB1	1.54e-05	182	37	4	ac7c83464487ecde3df6804a99551307bd768f21
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FMN2 CFAP54 CFAP43 FAM81B	1.61e-05	184	37	4	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	FMN2 CFAP54 CFAP43 FAM81B	1.64e-05	185	37	4	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FMN2 CFAP54 CFAP43 FAM81B	1.64e-05	185	37	4	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 CFAP43 UGT2A3 ABCB1	1.68e-05	186	37	4	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	FMN2 CFAP54 CFAP43 FAM81B	1.75e-05	188	37	4	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FMN2 CFAP54 CFAP43 FAM81B	1.75e-05	188	37	4	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FMN2 CFAP54 CFAP43 FAM81B	1.79e-05	189	37	4	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-PNs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	EIF1 EIF1B RSL24D1 COPB2	2.14e-05	198	37	4	6408653e956fedb284fa5e69ba8f4d620731f556
ToppCell	Mild/Remission-B_naive-9\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SRRM1 EIF1 EIF1B RSL24D1	2.19e-05	199	37	4	0451b1536be3725a520bfdd2b3dff133bea812e8
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FMN2 CFAP54 CFAP43 FAM81B	2.23e-05	200	37	4	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FMN2 CFAP54 CFAP43 FAM81B	2.23e-05	200	37	4	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGO2 BRCA1 ABCB1	2.21e-04	142	37	3	be63c48794a227ea55978524c0f5935342fc455e
ToppCell	ICU-SEP-Lymphocyte-T_NK-Treg\|ICU-SEP / Disease, Lineage and Cell Type	FBXO10 CCDC141 INF2	2.35e-04	145	37	3	ee99b58462f955b96d036aa67e343db047d66f64
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.50e-04	148	37	3	d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.50e-04	148	37	3	c8e93b87212f55774223caa385859c566fa1981f
ToppCell	Ciliated_cells-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	2.55e-04	149	37	3	6399c5a2f06d79f020dece252526f1c0c110d569
ToppCell	Ciliated_cells-A-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	2.65e-04	151	37	3	9d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.65e-04	151	37	3	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.65e-04	151	37	3	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.81e-04	154	37	3	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.81e-04	154	37	3	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.81e-04	154	37	3	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.81e-04	154	37	3	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.86e-04	155	37	3	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	2.86e-04	155	37	3	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGO2 BRCA1 C12orf56	2.97e-04	157	37	3	370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	CCDC141 INF2 KLRF2	3.31e-04	163	37	3	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 CFAP43 FAM81B	3.37e-04	164	37	3	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	3.37e-04	164	37	3	fd30c55d0d75ef8b9396435d836187168095152b
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGO2 BRCA1 ABCB1	3.49e-04	166	37	3	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SBK1 CCDC141 ABCB1	3.56e-04	167	37	3	94642b3dae035fedb6e8b9745f440096a4539f3c
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SBK1 CCDC141 ABCB1	3.56e-04	167	37	3	42b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SBK1 CCDC141 ABCB1	3.56e-04	167	37	3	ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	NBPF10 PRKG1 ZNF197	3.62e-04	168	37	3	1bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	NBPF10 PRKG1 ZNF197	3.62e-04	168	37	3	69f534de0f9a293047bea03cb1b78551087a8df5
ToppCell	3'_v3-Lung-Lymphocytic_Invariant-Inducer-like\|Lung / Manually curated celltypes from each tissue	PRKG1 EIF1 ABCB1	3.62e-04	168	37	3	b9bde6f542d730682d34a80e1f7f1609e5c699c7
ToppCell	Ciliated_cells-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP43 C12orf56 FAM81B	3.75e-04	170	37	3	3d3a03979014df3a05c49be18010c6b94d786707
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	CFAP54 CFAP43 FAM81B	3.81e-04	171	37	3	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	Healthy/Control-MAIT\|World / Disease group and Cell class	KIAA1210 KIAA1217 ABCB1	3.81e-04	171	37	3	61515114b17816a8f9ef6a57262eb9e977b6ede4
ToppCell	Healthy_donor-MAIT\|World / disease group, cell group and cell class (v2)	KIAA1210 KIAA1217 ABCB1	3.88e-04	172	37	3	6524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PRKG1 CCDC141 ABCB1	3.88e-04	172	37	3	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	3.88e-04	172	37	3	187ae91148d293537afc77e10da2b64302322224
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NBPF10 SGO2 BRCA1	4.01e-04	174	37	3	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	NS-critical-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SBK1 SGO2 BRCA1	4.15e-04	176	37	3	7cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.15e-04	176	37	3	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	SGO2 BRCA1 CCDC141	4.29e-04	178	37	3	829ea00c022a78d1861aa3ec53503272976775d9
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP54 CFAP43 FAM81B	4.29e-04	178	37	3	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	Control-T/NK-NK\|Control / Disease group,lineage and cell class （2021.01.30）	SBK1 CCDC141 ABCB1	4.29e-04	178	37	3	079fd19bdeed86bf985c4083af432432d66ad546
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TNFAIP2 PRKG1 KIAA1217	4.36e-04	179	37	3	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	FMN2 CFAP54 CFAP43	4.43e-04	180	37	3	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 CFAP43 FAM81B	4.50e-04	181	37	3	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SGO2 BRCA1 CCDC141	4.50e-04	181	37	3	9275531e896e118cee043ed94fd31a0070d9581c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 UGT2A3 ABCB1	4.50e-04	181	37	3	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP54 CFAP43 FAM81B	4.50e-04	181	37	3	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	FMN2 CFAP54 CFAP43	4.57e-04	182	37	3	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 UGT2A3 ABCB1	4.57e-04	182	37	3	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGO2 DEPDC7 BRCA1	4.57e-04	182	37	3	11494a66d986297b837332ee9d382b71b9f22591
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.57e-04	182	37	3	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	severe-multiplets\|severe / disease stage, cell group and cell class	SBK1 SGO2 DEPDC7	4.65e-04	183	37	3	78af8df48f0fe49ac37ccec0ad7b2993883b1148
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	SGO2 CFAP54 FAM81B	4.65e-04	183	37	3	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TNFAIP2 FBXO10 ZNF197	4.65e-04	183	37	3	3cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SGO2 DEPDC7 BRCA1	4.65e-04	183	37	3	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMN2 CFAP54 CFAP43	4.72e-04	184	37	3	797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	PRKG1 KIAA1217 ABCB1	4.72e-04	184	37	3	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMN2 CFAP54 CFAP43	4.72e-04	184	37	3	77d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCell	Ciliated_cells-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.79e-04	185	37	3	4fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	SBK1 KAT2B ABCB1	4.79e-04	185	37	3	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CFAP54 CFAP43 FAM81B	4.79e-04	185	37	3	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Ciliated_cells-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.79e-04	185	37	3	d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TNFAIP2 FBXO10 ZNF197	4.87e-04	186	37	3	bca5215d406f1785bf3a420201d5686071fcaca5
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP54 CFAP43 FAM81B	4.87e-04	186	37	3	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP54 CFAP43 FAM81B	4.87e-04	186	37	3	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 CFAP43 PRKG1	4.87e-04	186	37	3	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 CFAP43 PRKG1	4.95e-04	187	37	3	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	88f785932e67c613db0dda84496de351359ed962
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	8896a00b30d11b90ca42726d4e122174a30b161b
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	4.95e-04	187	37	3	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CFAP54 CFAP43 FAM81B	5.02e-04	188	37	3	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFAP54 CFAP43 FAM81B	5.02e-04	188	37	3	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNFAIP2 UGT2A3 ABCB1	5.10e-04	189	37	3	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	Ciliated\|World / shred by cell class for parenchyma	CFAP54 CFAP43 FAM81B	5.10e-04	189	37	3	711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCell	droplet-Limb_Muscle\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFAIP2 EIF1 TNMD	5.18e-04	190	37	3	06c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCell	Epithelial_cells-Ciliated_cells-B\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	CFAP54 CFAP43 FAM81B	5.18e-04	190	37	3	426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP54 CFAP43 FAM81B	5.18e-04	190	37	3	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFAP54 CFAP43 FAM81B	5.18e-04	190	37	3	169e600e95878000acf5d11f813f9028c7249646
Disease	gastroparesis	CFAP43 PRKG1	1.53e-04	16	34	2	EFO_1000948
Disease	HOMA-IR	KIAA1217 COPB2	6.65e-04	33	34	2	EFO_0004501
Disease	Benign Neoplasm	BRCA1 ABCB1	2.80e-03	68	34	2	C0086692
Disease	Neoplasms	BRCA1 ABCB1	2.80e-03	68	34	2	C0027651
Disease	Antihypertensive use measurement	SRRM1 KAT2B CCDC141	3.49e-03	265	34	3	EFO_0009927

Protein segments in the cluster

Peptide	Gene	Start	Entry
ENCKKLLKKLGKFSN	CFAP43	1566	Q8NDM7
LNKKANKSLKFKAAV	CFAP54	1386	Q96N23
IVKIFKNFKEKKSFK	COPB2	411	P35606
CIMQNNKFLVFKKKS	FBXO10	886	Q9UK96
KKKLVKAFKKKFACN	EIF1B	56	O60739
SAKEKKKLLGQFYKC	DEPDC7	486	Q96QD5
AKKKNFFKLNNKSEK	ABCB1	11	P08183
KKKACTLAQFLQKKF	MAGEB6	196	Q8N7X4
KCANILEKFFFSKIK	KAT2B	811	Q92831
KKIAKNAANLIKKLC	PRKG1	581	Q13976
KKKLVKAFKKKFACN	EIF1	56	P41567
KKSLNLNIFLKQFKC	INF2	636	Q27J81
LFFKNIKSTKNKAGK	FAM81B	21	Q96LP2
IKSFVKTKCKKNLLE	BRCA1	986	P38398
SFKNRCKSKQKSKDF	KLRF2	11	D3W0D1
DSFKDIKKKFNNLKF	CCDC141	911	Q6ZP82
IKKKFNNLKFNYTKK	CCDC141	916	Q6ZP82
GKKKCKFKALKSFFV	KIAA1210	161	Q9ULL0
FQKDLRKLKKDLKAC	FMN2	1576	Q9NZ56
LKFVNKSKTKLKNFL	SBK1	81	Q52WX2
QAYNKFCGKKVKEKL	MED19	91	A0JLT2
KKQQFRSLKEKCFLT	NBPF10	31	Q6P3W6
KKFKFKFPKKQLAAL	KIAA1217	1571	Q5T5P2
SCKAKNILTKAKNKL	SGO2	991	Q562F6
QLKFRKKKLKFCKSH	SETD1B	1821	Q9UPS6
CLRNKEFKNALKKAF	OR6B3	291	Q8NGW1
VLKKECKKSNSVRKF	C12orf56	111	Q8IXR9
NAEAFKSKKICKSLK	TNMD	16	Q9H2S6
KEKKKKSKGLANVFC	TNFAIP2	31	Q03169
KCNKCQKAFILKKSL	ZNF197	511	O14709
FNAKSKKCGLIKEKK	RLF	1511	Q13129
RFSNKQKKLLKQLKF	SRRM1	16	Q8IYB3
FCKSKCHKNFKKKRN	RSL24D1	31	Q9UHA3
ILFSFKKKNIFTKNK	VPS13C	2801	Q709C8
CQKGFKIQSKLLKHK	ZNF770	221	Q6IQ21
LFSCQKFNKTRKIEK	UGT2A3	511	Q6UWM9
FEDCKKTFKKHQQLK	GTF3A	136	Q92664
NLKIKFNKIAAEFKK	ZMYM1	721	Q5SVZ6