| GeneOntologyMolecularFunction | cysteine-type deubiquitinase activity | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 9.54e-20 | 114 | 165 | 19 | GO:0004843 |
| GeneOntologyMolecularFunction | deubiquitinase activity | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 5.03e-19 | 124 | 165 | 19 | GO:0101005 |
| GeneOntologyMolecularFunction | ubiquitin-like protein peptidase activity | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 3.53e-18 | 137 | 165 | 19 | GO:0019783 |
| GeneOntologyMolecularFunction | cysteine-type peptidase activity | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 2.16e-15 | 192 | 165 | 19 | GO:0008234 |
| GeneOntologyMolecularFunction | peptidase activity | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 ADAMTS8 AMZ2 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.11e-07 | 654 | 165 | 21 | GO:0008233 |
| GeneOntologyMolecularFunction | nucleoside-triphosphatase regulator activity | IPO5 RANBP2 SIPA1L3 TBC1D2B ALS2 TBC1D17 MADD CCDC88C ARHGAP4 RAB3GAP1 RGPD3 HERC1 ADAP2 | 3.11e-04 | 507 | 165 | 13 | GO:0060589 |
| GeneOntologyMolecularFunction | GTPase regulator activity | IPO5 RANBP2 SIPA1L3 TBC1D2B ALS2 TBC1D17 MADD CCDC88C ARHGAP4 RAB3GAP1 RGPD3 HERC1 ADAP2 | 3.11e-04 | 507 | 165 | 13 | GO:0030695 |
| GeneOntologyMolecularFunction | GTPase activator activity | RANBP2 SIPA1L3 TBC1D2B ALS2 TBC1D17 ARHGAP4 RAB3GAP1 RGPD3 ADAP2 | 5.36e-04 | 279 | 165 | 9 | GO:0005096 |
| GeneOntologyBiologicalProcess | protein deubiquitination | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.80e-19 | 125 | 160 | 19 | GO:0016579 |
| GeneOntologyBiologicalProcess | protein modification by small protein removal | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 2.85e-18 | 144 | 160 | 19 | GO:0070646 |
| GeneOntologyBiologicalProcess | post-translational protein modification | USP17L7 CDKN2A USP17L21 RANBP2 USP17L4 LZTR1 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 HLCS USP17L5 CUL9 USP17L10 USP17L19 ZNRF4 USP17L18 FBH1 USP17L17 MOCS3 TRIM56 USP17L3 HERC1 USP17L22 USP17L15 USP17L8 USP17L13 | 3.68e-09 | 1074 | 160 | 29 | GO:0043687 |
| GeneOntologyBiologicalProcess | protein modification by small protein conjugation or removal | USP17L7 CDKN2A USP17L21 RANBP2 USP17L4 LZTR1 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 CUL9 USP17L10 USP17L19 ZNRF4 USP17L18 FBH1 USP17L17 MOCS3 TRIM56 USP17L3 HERC1 USP17L22 USP17L15 USP17L8 USP17L13 | 3.93e-09 | 1009 | 160 | 28 | GO:0070647 |
| GeneOntologyBiologicalProcess | negative regulation of protein localization to nucleolus | CDKN2A POLR1A | 5.98e-05 | 2 | 160 | 2 | GO:1904750 |
| GeneOntologyCellularComponent | nuclear outer membrane-endoplasmic reticulum membrane network | USP17L7 USP17L21 RANBP2 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 PIEZO1 USP17L5 USP17L10 USP17L19 ZNRF4 RETSAT USP17L18 RAB3GAP1 SCAP USP17L17 SLC18A1 RGPD3 DIO1 USP17L3 TMEM39A FITM1 USP17L22 USP17L15 USP17L8 USP17L13 | 4.07e-07 | 1327 | 163 | 29 | GO:0042175 |
| GeneOntologyCellularComponent | endoplasmic reticulum membrane | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 PIEZO1 USP17L5 USP17L10 USP17L19 ZNRF4 RETSAT USP17L18 RAB3GAP1 SCAP USP17L17 SLC18A1 DIO1 USP17L3 TMEM39A FITM1 USP17L22 USP17L15 USP17L8 USP17L13 | 2.58e-06 | 1293 | 163 | 27 | GO:0005789 |
| GeneOntologyCellularComponent | endoplasmic reticulum subcompartment | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 PIEZO1 USP17L5 USP17L10 USP17L19 ZNRF4 RETSAT USP17L18 RAB3GAP1 SCAP USP17L17 SLC18A1 DIO1 USP17L3 TMEM39A FITM1 USP17L22 USP17L15 USP17L8 USP17L13 | 2.81e-06 | 1299 | 163 | 27 | GO:0098827 |
| MousePheno | increased trophectoderm apoptosis | USP17L2 USP17L15 USP17L13 | 2.18e-05 | 8 | 104 | 3 | MP:0012119 |
| MousePheno | increased thymus weight | CDKN2A USP17L2 USP17L15 USP17L13 | 2.74e-05 | 24 | 104 | 4 | MP:0004955 |
| Domain | HABP4_PAI-RBP1 | USP17L7 USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13 | 5.76e-28 | 16 | 157 | 14 | PF04774 |
| Domain | HABP4_PAIRBP1-bd | USP17L7 USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13 | 5.76e-28 | 16 | 157 | 14 | IPR006861 |
| Domain | UCH | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 3.43e-22 | 71 | 157 | 18 | PF00443 |
| Domain | USP_2 | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 3.43e-22 | 71 | 157 | 18 | PS00973 |
| Domain | USP_3 | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 4.54e-22 | 72 | 157 | 18 | PS50235 |
| Domain | USP_dom | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 4.54e-22 | 72 | 157 | 18 | IPR028889 |
| Domain | Peptidase_C19_UCH | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 4.54e-22 | 72 | 157 | 18 | IPR001394 |
| Domain | USP_CS | USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 3.81e-21 | 66 | 157 | 17 | IPR018200 |
| Domain | USP_1 | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13 | 1.16e-20 | 70 | 157 | 17 | PS00972 |
| Domain | Stereocilin-rel | OTOA STRC MSLN | 5.83e-07 | 3 | 157 | 3 | IPR026664 |
| Domain | DUF4599 | SPATA31A3 SPATA31A7 SPATA31A5 | 1.21e-04 | 12 | 157 | 3 | PF15371 |
| Domain | DUF4599 | SPATA31A3 SPATA31A7 SPATA31A5 | 1.21e-04 | 12 | 157 | 3 | IPR027970 |
| Pathway | REACTOME_RAS_PROCESSING | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 3.25e-27 | 45 | 109 | 18 | MM15671 |
| Pathway | REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 6.01e-15 | 191 | 109 | 18 | MM15289 |
| Pathway | REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES | USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 7.74e-14 | 221 | 109 | 18 | M27578 |
| Pathway | REACTOME_DEUBIQUITINATION | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.44e-12 | 262 | 109 | 18 | MM15286 |
| Pathway | REACTOME_MAPK_FAMILY_SIGNALING_CASCADES | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 TYK2 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 3.85e-12 | 318 | 109 | 19 | MM15278 |
| Pathway | REACTOME_DEUBIQUITINATION | USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.33e-11 | 299 | 109 | 18 | M27574 |
| Pathway | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | ENGASE OTOA CDKN2A USP17L21 RANBP2 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 CUL9 RTN4RL1 USP17L10 USP17L19 ADAMTS8 SSPOP B3GNT8 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 MSLN USP17L8 USP17L13 | 4.99e-06 | 1475 | 109 | 28 | M19806 |
| Pathway | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | USP17L7 ENGASE OTOA USP17L21 RANBP2 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 ADAMTS8 SSPOP B3GNT8 USP17L18 USP17L17 RGPD3 USP17L3 USP17L22 USP17L15 MSLN USP17L8 USP17L13 | 1.53e-05 | 1389 | 109 | 26 | MM15307 |
| Pubmed | DUB-1, a deubiquitinating enzyme with growth-suppressing activity. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-40 | 21 | 166 | 18 | 8622927 |
| Pubmed | DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-40 | 21 | 166 | 18 | 14583620 |
| Pubmed | DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-40 | 21 | 166 | 18 | 11468161 |
| Pubmed | The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-40 | 21 | 166 | 18 | 8756639 |
| Pubmed | Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-40 | 21 | 166 | 18 | 12447969 |
| Pubmed | DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-40 | 21 | 166 | 18 | 18980247 |
| Pubmed | JAK2 is required for induction of the murine DUB-1 gene. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.59e-39 | 22 | 166 | 18 | 9154835 |
| Pubmed | DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 8.39e-38 | 24 | 166 | 18 | 8995226 |
| Pubmed | Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 2.98e-37 | 25 | 166 | 18 | 21115691 |
| Pubmed | Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 9.65e-37 | 26 | 166 | 18 | 35816173 |
| Pubmed | Cdc25A and Dub3 in a high-stakes balancing act. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 2.10e-36 | 33 | 166 | 19 | 20228807 |
| Pubmed | The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 20403174 |
| Pubmed | DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 14699124 |
| Pubmed | The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 15780755 |
| Pubmed | USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 19188362 |
| Pubmed | Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 11941478 |
| Pubmed | Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 17109758 |
| Pubmed | The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 20388806 |
| Pubmed | Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 20715989 |
| Pubmed | Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 9806828 |
| Pubmed | The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 20368735 |
| Pubmed | The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 10936051 |
| Pubmed | The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.75e-36 | 34 | 166 | 19 | 21448158 |
| Pubmed | Cytokine-regulated protein degradation by the ubiquitination system. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.03e-35 | 35 | 166 | 19 | 16611142 |
| Pubmed | Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.03e-35 | 35 | 166 | 19 | 21239494 |
| Pubmed | Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 2.11e-35 | 29 | 166 | 18 | 32527007 |
| Pubmed | The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 2.18e-35 | 36 | 166 | 19 | 20147298 |
| Pubmed | Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.47e-35 | 37 | 166 | 19 | 20228808 |
| Pubmed | DUX is a non-essential synchronizer of zygotic genome activation. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 PRAMEF12 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 7.29e-32 | 50 | 166 | 19 | 31806660 |
| Pubmed | USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 PRAMEF12 USP17L10 USP17L19 ADAMTS8 ZXDA USP17L18 DUSP23 USP17L17 SIGLEC6 NYNRIN USP17L3 USP17L22 USP17L15 MSLN USP17L8 USP17L13 | 2.33e-15 | 674 | 166 | 25 | 37196079 |
| Pubmed | High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency. | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8 | 5.89e-15 | 10 | 166 | 7 | 24207026 |
| Pubmed | Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells. | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8 | 3.86e-14 | 12 | 166 | 7 | 24695638 |
| Pubmed | ES cell neural differentiation reveals a substantial number of novel ESTs. | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8 | 1.66e-13 | 14 | 166 | 7 | 11793228 |
| Pubmed | CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8 | 2.39e-12 | 19 | 166 | 7 | 28067227 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | ENGASE FLNC EPPK1 LZTR1 MYO10 PIEZO1 SIPA1L3 KHNYN PER1 PEX6 CUL9 CHD8 ANKLE1 TXNRD2 FAAP100 AHDC1 TBC1D17 MADD TYK2 CCDC88C SCAP MAP1S MLLT1 ZFYVE26 GPC2 HERC1 BRAT1 | 3.34e-12 | 1105 | 166 | 27 | 35748872 |
| Pubmed | The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. | SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1 | 7.45e-09 | 6 | 166 | 4 | 20850414 |
| Pubmed | Targeted disruption of the spermatid-specific gene Spata31 causes male infertility. | SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1 | 7.45e-09 | 6 | 166 | 4 | 25930072 |
| Pubmed | A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220. | USP17L21 USP17L12 USP17L20 USP17L11 USP17L19 USP17L18 DNAAF5 USP17L17 | 1.14e-07 | 119 | 166 | 8 | 28625976 |
| Pubmed | Human and mouse proteases: a comparative genomic approach. | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8 | 1.28e-07 | 81 | 166 | 7 | 12838346 |
| Pubmed | Embryonic demise caused by targeted disruption of a cysteine protease Dub-2. | USP17L2 USP17L15 USP17L13 | 4.26e-07 | 4 | 166 | 3 | 22984479 |
| Pubmed | DNA sequence and analysis of human chromosome 8. | USP17L7 USP17L4 USP17L1 USP17L3 USP17L8 | 3.38e-06 | 48 | 166 | 5 | 16421571 |
| Pubmed | Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. | SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1 | 4.94e-06 | 24 | 166 | 4 | 32212159 |
| Pubmed | Clarin-2 is essential for hearing by maintaining stereocilia integrity and function. | CTBP2 STRC STRCP1 | 1.71e-05 | 11 | 166 | 3 | 31448880 |
| Pubmed | Uncovering a new role for peroxidase enzymes as drivers of angiogenesis. | MPO EPX | 2.26e-05 | 2 | 166 | 2 | 26386352 |
| Pubmed | Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment. | MPO EPX | 2.26e-05 | 2 | 166 | 2 | 28260049 |
| Pubmed | Eosinophil associated genes in the inflammatory bowel disease 4 region: correlation to inflammatory bowel disease revealed. | EPX RNASE3 | 2.26e-05 | 2 | 166 | 2 | 23197886 |
| Pubmed | CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome. | CHD8 CHD7 | 2.26e-05 | 2 | 166 | 2 | 20453063 |
| Pubmed | CtBP2 contributes to malignant development of human esophageal squamous cell carcinoma by regulation of p16INK4A. | CDKN2A CTBP2 | 2.26e-05 | 2 | 166 | 2 | 23255392 |
| Pubmed | Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss. | STRC STRCP1 | 2.26e-05 | 2 | 166 | 2 | 34910522 |
| Pubmed | [The auxiliary diagnostic value of ECP and MPO expression in nasal secretions in different types of rhinitis]. | MPO RNASE3 | 2.26e-05 | 2 | 166 | 2 | 38563171 |
| Pubmed | New markers: urine xanthine oxidase and myeloperoxidase in the early detection of urinary tract infection. | MPO XDH | 2.26e-05 | 2 | 166 | 2 | 24591758 |
| Pubmed | Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect. | MPO EPX | 2.26e-05 | 2 | 166 | 2 | 7809065 |
| Pubmed | CGIN1: a retroviral contribution to mammalian genomes. | KHNYN NYNRIN | 2.26e-05 | 2 | 166 | 2 | 19561090 |
| Pubmed | C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A. | CDKN2A CTBP2 | 2.26e-05 | 2 | 166 | 2 | 28412731 |
| Pubmed | Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus. | STRC STRCP1 | 2.26e-05 | 2 | 166 | 2 | 11687802 |
| Pubmed | Peroxidase enzymes inhibit osteoclast differentiation and bone resorption. | MPO EPX | 2.26e-05 | 2 | 166 | 2 | 27836774 |
| Pubmed | Immunohistochemical detection and clinicopathological significance of JARID1B/KDM5B and P16 expression in invasive ductal carcinoma of the breast. | CDKN2A KDM5B | 2.26e-05 | 2 | 166 | 2 | 26125737 |
| Pubmed | Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators. | CHD8 CHD7 | 2.26e-05 | 2 | 166 | 2 | 24211491 |
| Pubmed | EphA2 proteomics in human keratinocytes reveals a novel association with afadin and epidermal tight junctions. | EPHA2 AFDN | 2.26e-05 | 2 | 166 | 2 | 27815408 |
| Pubmed | The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner. | EPX RNASE3 | 2.26e-05 | 2 | 166 | 2 | 24738159 |
| Pubmed | Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity. | CDKN2A LZTR1 WRNIP1 PER1 HLCS PEX6 CUL9 CHD8 FBXL6 ADH4 TYK2 ARHGAP4 LRIG3 TRIM56 NFKBIL1 MLLT1 PHIP | 2.69e-05 | 1116 | 166 | 17 | 31753913 |
| Pubmed | Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics. | STRC STRCP1 | 6.77e-05 | 3 | 166 | 2 | 30801007 |
| Pubmed | The potential for repositioning antithyroid agents as antiasthma drugs. | MPO EPX | 6.77e-05 | 3 | 166 | 2 | 27444178 |
| Pubmed | Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model. | MPO EPX | 6.77e-05 | 3 | 166 | 2 | 30565999 |
| Pubmed | The evolutionary conservation of the mammalian peroxidase genes. | MPO EPX | 6.77e-05 | 3 | 166 | 2 | 12584448 |
| Pubmed | The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities. | CHD8 CHD7 | 6.77e-05 | 3 | 166 | 2 | 28533432 |
| Pubmed | Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8. | CHD8 CHD7 | 6.77e-05 | 3 | 166 | 2 | 30108144 |
| Pubmed | Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis. | CDKN2A CTBP2 | 6.77e-05 | 3 | 166 | 2 | 16508011 |
| Pubmed | Thiocyanate modulates the catalytic activity of mammalian peroxidases. | MPO EPX | 6.77e-05 | 3 | 166 | 2 | 15894800 |
| Pubmed | Autism-linked CHD gene expression patterns during development predict multi-organ disease phenotypes. | CHD8 CHD7 | 6.77e-05 | 3 | 166 | 2 | 30277262 |
| Pubmed | The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17. | MPO EPX | 6.77e-05 | 3 | 166 | 2 | 10828600 |
| Pubmed | Myeloperoxidase, xanthine oxidase and superoxide dismutase in the gastric mucosa of Helicobacter pylori positive and negative pediatric patients. | MPO XDH | 6.77e-05 | 3 | 166 | 2 | 16758302 |
| Pubmed | Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1. | OTOA STRC STRCP1 | 6.91e-05 | 17 | 166 | 3 | 20856818 |
| Pubmed | Stereocilin-deficient mice reveal the origin of cochlear waveform distortions. | STRC STRCP1 | 1.35e-04 | 4 | 166 | 2 | 18849963 |
| Pubmed | Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex. | CHD8 CHD7 | 1.35e-04 | 4 | 166 | 2 | 23285124 |
| Pubmed | Expression levels of eosinophil granule protein mRNAs in induced sputum reflect airway hyperresponsiveness and airflow limitation. | EPX RNASE3 | 1.35e-04 | 4 | 166 | 2 | 24814827 |
| Pubmed | Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. | KHNYN MADD MAST4 ZFYVE26 DNAH9 | 1.46e-04 | 104 | 166 | 5 | 9205841 |
| Pubmed | Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany. | EPX RNASE3 | 2.24e-04 | 5 | 166 | 2 | 19014520 |
| Pubmed | NONO couples the circadian clock to the cell cycle. | CDKN2A PER1 | 2.24e-04 | 5 | 166 | 2 | 23267082 |
| Pubmed | CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis. | CASR CHD8 | 2.24e-04 | 5 | 166 | 2 | 19151705 |
| Pubmed | The NYN domains: novel predicted RNAses with a PIN domain-like fold. | KHNYN NYNRIN | 2.24e-04 | 5 | 166 | 2 | 17114934 |
| Pubmed | An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells. | STRC STRCP1 | 2.24e-04 | 5 | 166 | 2 | 24920589 |
| Pubmed | Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. | HDHD3 MCMBP LRRC57 TOR2A ZSWIM5 PIEZO1 CHD8 FAAP100 AHDC1 DALRD3 AMZ2 FREM2 SCAP RHOBTB1 FER1L4 CTBP2 | 2.49e-04 | 1215 | 166 | 16 | 15146197 |
| Pubmed | A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. | MPO IPO5 FLNC RANBP2 MCMBP LZTR1 WRNIP1 FAAP100 TYK2 DNAAF5 DUSP23 EPHA2 AFDN VPS29 | 2.57e-04 | 974 | 166 | 14 | 28675297 |
| Pubmed | Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers. | TBC1D2B TBC1D17 VPS29 | 2.87e-04 | 27 | 166 | 3 | 22354992 |
| Pubmed | Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. | PGBD1 CR1 SORCS1 | 3.20e-04 | 28 | 166 | 3 | 20534741 |
| Pubmed | LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL. | CDKN2A LZTR1 | 3.35e-04 | 6 | 166 | 2 | 36445254 |
| Pubmed | CHARGE and Kabuki syndromes: a phenotypic and molecular link. | CHD8 CHD7 | 3.35e-04 | 6 | 166 | 2 | 24705355 |
| Pubmed | Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. | RAPSN CDK10 TYK2 FBH1 RHOBTB1 EPHA2 TRIM56 RPS6KL1 | 4.42e-04 | 372 | 166 | 8 | 22939624 |
| Pubmed | Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells. | IPO5 KDM5B RANBP2 CHD8 CHD7 AHDC1 TOE1 AMZ2 PHIP | 4.48e-04 | 469 | 166 | 9 | 27634302 |
| Pubmed | Glutathione S-transferase P1 and NADPH quinone oxidoreductase polymorphisms are associated with aberrant promoter methylation of P16(INK4a) and O(6)-methylguanine-DNA methyltransferase in sputum. | MPO CDKN2A | 4.68e-04 | 7 | 166 | 2 | 11956078 |
| Pubmed | Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 9037092 |
| Pubmed | Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 11353387 |
| Pubmed | Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 30944974 |
| Pubmed | Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 38838144 |
| Pubmed | Retina-specifically expressed novel subtypes of bovine cyclophilin. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 7559465 |
| Pubmed | Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 17372272 |
| Pubmed | Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 38657106 |
| Pubmed | Genome-wide association study identifies three loci associated with melanoma risk. | CDKN2A CDK10 | 4.68e-04 | 7 | 166 | 2 | 19578364 |
| Pubmed | Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis. | RANBP2 RGPD3 | 4.68e-04 | 7 | 166 | 2 | 21205196 |
| Interaction | TOP3B interactions | IPO5 ENGASE FLNC EPPK1 LZTR1 MYO10 PIEZO1 SIPA1L3 KHNYN PER1 PEX6 CUL9 CHD8 ANKLE1 TXNRD2 FAAP100 AHDC1 TBC1D17 MADD FBXL6 TYK2 CCDC88C SCAP MAP1S TRIM56 MLLT1 ZFYVE26 GPC2 HERC1 BRAT1 EXOC4 | 2.63e-07 | 1470 | 156 | 31 | int:TOP3B |
| Cytoband | 4p16.1 | USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L22 USP17L15 USP17L13 | 2.60e-18 | 79 | 167 | 13 | 4p16.1 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr4p16 | USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L22 USP17L15 USP17L13 | 2.25e-12 | 222 | 167 | 13 | chr4p16 |
| Cytoband | 8p23.1 | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L8 | 2.28e-05 | 154 | 167 | 6 | 8p23.1 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr8p23 | USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L8 | 2.29e-04 | 234 | 167 | 6 | chr8p23 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr9q12 | SPATA31A7 SPATA31A5 | 3.63e-04 | 8 | 167 | 2 | chr9q12 |
| Cytoband | 14q12 | KHNYN NYNRIN FITM1 | 1.08e-03 | 55 | 167 | 3 | 14q12 |
| Cytoband | 17q23.1 | MPO EPX | 1.53e-03 | 16 | 167 | 2 | 17q23.1 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr17p13 | SLC16A13 PER1 RTN4RL1 MRM3 SHPK SERPINF2 | 1.75e-03 | 346 | 167 | 6 | chr17p13 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19p13 | IZUMO4 PLK5 ANKLE1 ZNRF4 TYK2 MAP1S USHBP1 MLLT1 ZSWIM4 | 2.70e-03 | 797 | 167 | 9 | chr19p13 |
| Cytoband | 9p13.1 | SPATA31A3 SPATA31A1 | 3.44e-03 | 24 | 167 | 2 | 9p13.1 |
| Cytoband | 15q15.3 | STRC STRCP1 | 3.73e-03 | 25 | 167 | 2 | 15q15.3 |
| Coexpression | MADAN_DPPA4_TARGETS | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 RASIP1 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.23e-24 | 86 | 161 | 19 | MM1312 |
| Coexpression | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.01e-20 | 112 | 161 | 18 | MM1095 |
| Coexpression | GERY_CEBP_TARGETS | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 XDH USP17L10 USP17L19 USP17L18 RNASE3 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 1.20e-20 | 160 | 161 | 20 | MM1155 |
| Coexpression | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | USP17L7 USP17L21 USP17L4 LRRC57 LZTR1 USP17L2 USP17L12 USP17L1 TOR2A USP17L20 USP17L11 USP17L5 ALS2 USP17L10 USP17L19 USP17L18 USP17L17 SLC18A1 RNASEH2C USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 EXOC4 | 2.36e-13 | 647 | 161 | 25 | MM981 |
| Coexpression | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | USP17L7 USP17L21 KDM5B USP17L4 LRRC57 LZTR1 USP17L2 USP17L12 USP17L1 TOR2A USP17L20 USP17L11 PEX6 CMPK2 USP17L5 USP17L10 USP17L19 RETSAT USP17L18 USP17L17 SLC18A1 EPHA2 RNASEH2C USP17L3 HERC1 USP17L22 USP17L15 USP17L8 USP17L13 EXOC4 | 8.15e-11 | 1226 | 161 | 30 | MM979 |
| Coexpression | BRUINS_UVC_RESPONSE_LATE | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 PER1 USP17L5 ALS2 USP17L10 USP17L19 RETSAT SORCS1 USP17L18 CCDC88C LRIG3 USP17L17 SURF2 USP17L3 AFDN CTBP2 USP17L22 USP17L15 USP17L8 USP17L13 | 4.79e-09 | 1198 | 161 | 27 | MM1062 |
| Coexpression | MARSON_BOUND_BY_FOXP3_STIMULATED | USP17L7 USP17L21 KDM5B USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 KHNYN PER1 USP17L5 C1orf74 USP17L10 USP17L19 AMZ2 USP17L18 RAB3GAP1 USP17L17 USP17L3 HERC1 USP17L22 USP17L15 USP17L8 USP17L13 | 9.80e-09 | 1072 | 161 | 25 | MM1031 |
| Coexpression | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | IPO5 LZTR1 TOR2A MYO10 CHD7 B3GNT8 CCDC88C RNASEH2C VPS29 | 4.30e-06 | 200 | 161 | 9 | M7026 |
| Coexpression | BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_DN | TBC1D2B FAAP100 CDK10 TYK2 | 3.79e-05 | 31 | 161 | 4 | M4671 |
| Disease | primary ovarian insufficiency (implicated_via_orthology) | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 4.41e-32 | 46 | 153 | 19 | DOID:5426 (implicated_via_orthology) |
| Disease | congenital heart disease (implicated_via_orthology) | USP17L7 USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 CHD8 USP17L10 CHD7 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13 | 5.37e-32 | 69 | 153 | 21 | DOID:1682 (implicated_via_orthology) |
| Disease | autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology) | STRC STRCP1 | 2.67e-05 | 2 | 153 | 2 | DOID:0110471 (implicated_via_orthology) |
| Disease | neurilemmoma (is_implicated_in) | CDKN2A LZTR1 | 7.99e-05 | 3 | 153 | 2 | DOID:3192 (is_implicated_in) |
| Disease | Perineurioma | CDKN2A FOXR2 | 2.64e-04 | 5 | 153 | 2 | C0751691 |
| Disease | Nerve Sheath Tumors | CDKN2A FOXR2 | 2.64e-04 | 5 | 153 | 2 | C0206727 |
| Disease | Peripheral Nerve Sheath Neoplasm | CDKN2A FOXR2 | 2.64e-04 | 5 | 153 | 2 | C0751689 |
| Disease | CHARGE syndrome (implicated_via_orthology) | CHD8 CHD7 | 5.51e-04 | 7 | 153 | 2 | DOID:0050834 (implicated_via_orthology) |
| Disease | Hyperuricemia | XDH SLC5A8 | 5.51e-04 | 7 | 153 | 2 | C0740394 |
| Disease | 1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement | RAPSN PEX6 | 7.33e-04 | 8 | 153 | 2 | EFO_0800392 |
| Disease | mitochondrial DNA measurement | SMUG1 ANKLE1 CHD7 ZNRF4 CDK10 USHBP1 ADAP2 | 1.67e-03 | 328 | 153 | 7 | EFO_0006312 |
| Disease | bilirubin measurement | RAPSN PIEZO1 SIPA1L3 PEX6 EPX ADH4 SCAP PHIP | 2.23e-03 | 442 | 153 | 8 | EFO_0004570 |
| Disease | delta-6 desaturase measurement | RAPSN MAST4 | 2.68e-03 | 15 | 153 | 2 | EFO_0007765 |
| Disease | Congenital total cataract | SIPA1L3 EPHA2 | 3.06e-03 | 16 | 153 | 2 | C0266539 |
| Disease | open-angle glaucoma | RAPSN DGKG ADAMTS8 TXNRD2 MADD | 3.26e-03 | 191 | 153 | 5 | EFO_0004190 |
| Disease | parahippocampal gyrus volume measurement | XDH FREM2 | 3.87e-03 | 18 | 153 | 2 | EFO_0010318 |
