Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C3 AKR1C4 AKR1C2 ADH4

2.02e-0814444GO:0004032
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C3 AKR1C4 AKR1C2

3.99e-084443GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C3 AKR1C4 AKR1C2

3.99e-084443GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C3 AKR1C4 AKR1C2

3.99e-084443GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:0047006
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:0047787
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C3 AKR1C4 AKR1C2

9.95e-085443GO:0047086
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C3 AKR1C4 AKR1C2

1.99e-076443GO:0045550
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C3 AKR1C4 AKR1C2 ADH4

2.11e-0724444GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C3 AKR1C4 AKR1C2 ADH4

2.96e-0726444GO:0004022
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C2 ADH4

3.47e-0727444GO:0008106
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C2

3.47e-077443GO:0072582
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4 AKR1C2 ADH4

5.39e-0730444GO:0018455
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

5.55e-078443GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

5.55e-078443GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C3 AKR1C4 AKR1C2

5.55e-078443GO:0035671
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C3 AKR1C4 AKR1C2 ADH4

7.05e-0732444GO:0004033
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

8.31e-079443GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C3 AKR1C4 AKR1C2

8.31e-079443GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C2

1.19e-0610443GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C3 AKR1C4 AKR1C2

1.19e-0610443GO:0032052
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

3.57e-0614443GO:0001758
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C2 ADH4

3.72e-0648444GO:0016620
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C3 AKR1C4 AKR1C2 ADH4

6.93e-0656444GO:0016903
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C3 AKR1C4 AKR1C2 ADH4

9.14e-0660444GO:0016655
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4 AKR1C2

1.11e-0520443GO:0004303
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2

1.42e-053442GO:0005220
GeneOntologyMolecularFunctionNADPH binding

AKR1C3 AKR1C4 AKR1C2

2.51e-0526443GO:0070402
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C2

5.20e-0533443GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

AKR1C3 AKR1C4 AKR1C2 ADH4

5.64e-0595444GO:0016651
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C2

5.69e-0534443GO:0016628
GeneOntologyMolecularFunctionalcohol binding

ITPR1 ITPR2 PMP2 ADH4

7.45e-05102444GO:0043178
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C3 AKR1C4 AKR1C2

8.63e-0539443GO:0016229
GeneOntologyMolecularFunctionmonocarboxylic acid binding

AKR1C3 AKR1C4 AKR1C2 PMP2

8.97e-05107444GO:0033293
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C3 AKR1C4 AKR1C2

9.32e-0540443GO:0016709
GeneOntologyMolecularFunctiontestosterone dehydrogenase (NAD+) activity

AKR1C3 AKR1C4

1.69e-049442GO:0047035
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C2 ADH4

1.74e-04127444GO:0016616
GeneOntologyMolecularFunctionsteroid binding

AKR1C3 AKR1C4 AKR1C2 PMP2

2.08e-04133444GO:0005496
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

AKR1C3 AKR1C4 AKR1C2 ADH4

2.39e-04138444GO:0016614
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4

2.58e-0411442GO:0030283
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C3 AKR1C4 AKR1C2

3.45e-0462443GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C3 AKR1C4 AKR1C2

3.45e-0462443GO:0050661
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2

4.25e-0414442GO:0070679
GeneOntologyMolecularFunctiontransmembrane transporter binding

AP2M1 YES1 ITPR1 ITPR2

5.52e-04172444GO:0044325
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2

7.10e-0418442GO:0015278
GeneOntologyMolecularFunctionlipid binding

AKR1C3 AP2M1 AKR1C4 AKR1C2 ITPR1 ITPR2 PMP2 ADH4

1.26e-03988448GO:0008289
GeneOntologyMolecularFunctioncarboxylic acid binding

AKR1C3 AKR1C4 AKR1C2 PMP2

1.87e-03239444GO:0031406
GeneOntologyMolecularFunctionmonooxygenase activity

AKR1C3 AKR1C4 AKR1C2

2.08e-03115443GO:0004497
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2

2.12e-0331442GO:0099604
GeneOntologyMolecularFunctionorganic acid binding

AKR1C3 AKR1C4 AKR1C2 PMP2

2.33e-03254444GO:0043177
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2

2.40e-0333442GO:0005217
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

HLTF UPF1 TOP3A RAD9A

2.60e-03262444GO:0140097
GeneOntologyMolecularFunctionsingle-stranded DNA binding

MMS22L MCM10 TOP3A

3.20e-03134443GO:0003697
GeneOntologyMolecularFunctionchannel inhibitor activity

SLC15A1 ITPR1

5.44e-0350442GO:0016248
GeneOntologyMolecularFunctiontransporter inhibitor activity

SLC15A1 ITPR1

5.65e-0351442GO:0141110
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

AKR1C3 AKR1C4 AKR1C2

8.93e-03194443GO:0016705
GeneOntologyMolecularFunctionprotein domain specific binding

PXN AP2M1 CLDN7 CHMP2B RAD9A ITPR1

1.19e-02875446GO:0019904
GeneOntologyMolecularFunctionzinc ion binding

HLTF UPF1 ADAMTS4 SF1 TOP3A ADH4

1.29e-02891446GO:0008270
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C3 AKR1C4 AKR1C2

3.88e-084453GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C3 AKR1C4 AKR1C2

3.88e-084453GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C3 AKR1C4 AKR1C2

3.88e-084453GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C3 AKR1C4 AKR1C2

3.88e-084453GO:0008208
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C3 AKR1C4 AKR1C2

9.67e-085453GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C3 AKR1C4 AKR1C2

9.67e-085453GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C3 AKR1C4 AKR1C2

9.67e-085453GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C3 AKR1C4 AKR1C2

9.67e-085453GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C3 AKR1C4 AKR1C2

9.67e-085453GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

9.67e-085453GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C3 AKR1C4 AKR1C2

1.93e-076453GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C3 AKR1C4 AKR1C2

1.93e-076453GO:0016095
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

3.38e-077453GO:1900052
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C3 AKR1C4 AKR1C2

3.38e-077453GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C3 AKR1C4 AKR1C2

3.38e-077453GO:0071799
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C3 AKR1C4 AKR1C2

8.08e-079453GO:0044597
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C3 AKR1C4 AKR1C2

1.15e-0610453GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C3 AKR1C4 AKR1C2

1.15e-0610453GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C3 AKR1C4 AKR1C2

1.15e-0610453GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C3 AKR1C4 AKR1C2

1.15e-0610453GO:0030647
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C3 AKR1C4 AKR1C2

1.15e-0610453GO:0044598
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C3 AKR1C4 AKR1C2

1.58e-0611453GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C3 AKR1C4 AKR1C2

1.58e-0611453GO:0016115
GeneOntologyBiologicalProcessalcohol catabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

3.29e-0647454GO:0046164
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

3.47e-0614453GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C3 AKR1C4 AKR1C2

3.47e-0614453GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

4.34e-0615453GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C3 AKR1C4 AKR1C2

5.33e-0616453GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C3 AKR1C4 AKR1C2

5.33e-0616453GO:0032351
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C3 AKR1C4 AKR1C2

7.74e-0618453GO:0030656
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

AKR1C3 AKR1C4 UPF1 AKR1C2 SF1

8.85e-06129455GO:0048024
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C3 AKR1C4 AKR1C2

1.26e-0521453GO:0048385
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C3 AKR1C4 AKR1C2

1.26e-0521453GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

1.26e-0521453GO:0016114
GeneOntologyBiologicalProcessretinal metabolic process

AKR1C3 AKR1C4 AKR1C2

1.26e-0521453GO:0042574
GeneOntologyBiologicalProcessketone catabolic process

AKR1C3 AKR1C4 AKR1C2

1.26e-0521453GO:0042182
GeneOntologyBiologicalProcessparturition

AKR1C3 AKR1C4 AKR1C2

1.45e-0522453GO:0007567
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C3 AKR1C4 AKR1C2

1.45e-0522453GO:1902644
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C3 AKR1C4 AKR1C2

1.45e-0522453GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C3 AKR1C4 AKR1C2

1.45e-0522453GO:0042448
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C3 AKR1C4 AKR1C2

1.67e-0523453GO:0071379
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C3 AKR1C4 AKR1C2

1.67e-0523453GO:0034310
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

1.93e-0573454GO:1901616
GeneOntologyBiologicalProcessregulation of mRNA processing

AKR1C3 AKR1C4 UPF1 AKR1C2 SF1

2.36e-05158455GO:0050684
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C3 AKR1C4 AKR1C2

2.44e-0526453GO:0010566
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C3 AKR1C4 AKR1C2

3.06e-0528453GO:0048025
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C3 AKR1C4 AKR1C2

3.41e-0529453GO:0050686
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C3 AKR1C4 AKR1C2

3.41e-0529453GO:0016093
GeneOntologyBiologicalProcessretinoid metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

4.22e-0589454GO:0001523
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C3 AKR1C4 AKR1C2

4.60e-0532453GO:2000353
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C3 AKR1C4 AKR1C2

5.06e-0533453GO:0033119
GeneOntologyBiologicalProcessditerpenoid metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

5.22e-0594454GO:0016101
GeneOntologyBiologicalProcessaldehyde metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

5.44e-0595454GO:0006081
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C3 AKR1C4 AKR1C2

5.54e-0534453GO:0006706
GeneOntologyBiologicalProcessresponse to alcohol

RPL10A AKR1C3 AKR1C4 CLDN7 AKR1C2 ITPR2

5.66e-05312456GO:0097305
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C3 AKR1C4 AKR1C2

6.05e-0535453GO:0120255
GeneOntologyBiologicalProcessresponse to prostaglandin

AKR1C3 AKR1C4 AKR1C2

6.59e-0536453GO:0034694
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

6.59e-0536453GO:0008299
GeneOntologyBiologicalProcessDNA repair

PAXIP1 ESCO2 HLTF MMS22L UPF1 SMCHD1 TOP3A RAD9A

7.01e-05648458GO:0006281
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

AKR1C3 AKR1C4 AKR1C2

7.76e-0538453GO:0048384
GeneOntologyBiologicalProcessterpenoid metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

8.05e-05105454GO:0006721
GeneOntologyBiologicalProcessprimary alcohol metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

8.35e-05106454GO:0034308
GeneOntologyBiologicalProcessregulation of steroid biosynthetic process

AKR1C3 AKR1C4 AKR1C2 SF1

8.35e-05106454GO:0050810
GeneOntologyBiologicalProcessregulation of RNA splicing

AKR1C3 AKR1C4 UPF1 AKR1C2 SF1

8.55e-05207455GO:0043484
GeneOntologyBiologicalProcessDNA metabolic process

PAXIP1 ESCO2 HLTF MMS22L UPF1 MCM10 TBRG1 SMCHD1 TOP3A RAD9A

8.92e-0510814510GO:0006259
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C3 AKR1C4 AKR1C2

9.06e-0540453GO:0042573
GeneOntologyBiologicalProcesscellular response to fatty acid

AKR1C3 AKR1C4 AKR1C2

1.05e-0442453GO:0071398
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

AKR1C3 AKR1C4 UPF1 PRPF3 AKR1C2 SF1

1.21e-04358456GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

AKR1C3 AKR1C4 UPF1 PRPF3 AKR1C2 SF1

1.21e-04358456GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

AKR1C3 AKR1C4 UPF1 PRPF3 AKR1C2 SF1

1.28e-04362456GO:0000375
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

AKR1C3 AKR1C4 AKR1C2

1.29e-0445453GO:0008207
GeneOntologyBiologicalProcesscellular response to alcohol

AKR1C3 AKR1C4 AKR1C2 ITPR2

1.84e-04130454GO:0097306
GeneOntologyBiologicalProcessDNA damage response

PAXIP1 ESCO2 HLTF MMS22L UPF1 MCM10 SMCHD1 TOP3A RAD9A

1.91e-04959459GO:0006974
GeneOntologyBiologicalProcessregulation of steroid metabolic process

AKR1C3 AKR1C4 AKR1C2 SF1

2.12e-04135454GO:0019218
GeneOntologyBiologicalProcessprostaglandin metabolic process

AKR1C3 AKR1C4 AKR1C2

2.48e-0456453GO:0006693
GeneOntologyBiologicalProcessprostanoid metabolic process

AKR1C3 AKR1C4 AKR1C2

2.61e-0457453GO:0006692
GeneOntologyBiologicalProcessketone biosynthetic process

AKR1C3 AKR1C4 AKR1C2

2.61e-0457453GO:0042181
GeneOntologyBiologicalProcessisoprenoid metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

2.72e-04144454GO:0006720
GeneOntologyBiologicalProcessregulation of hormone metabolic process

AKR1C3 AKR1C4 AKR1C2

2.75e-0458453GO:0032350
GeneOntologyBiologicalProcesspositive regulation of epithelial cell apoptotic process

AKR1C3 AKR1C4 AKR1C2

3.04e-0460453GO:1904037
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C3 AKR1C4 AKR1C2

4.22e-0467453GO:0019748
GeneOntologyBiologicalProcessresponse to fatty acid

AKR1C3 AKR1C4 AKR1C2

4.60e-0469453GO:0070542
GeneOntologyBiologicalProcessregulation of endothelial cell apoptotic process

AKR1C3 AKR1C4 AKR1C2

5.64e-0474453GO:2000351
GeneOntologyBiologicalProcessDNA replication

ESCO2 MMS22L UPF1 MCM10 TBRG1

5.71e-04312455GO:0006260
GeneOntologyBiologicalProcessolefinic compound metabolic process

AKR1C3 AKR1C4 AKR1C2 ADH4

6.32e-04180454GO:0120254
GeneOntologyBiologicalProcessendothelial cell apoptotic process

AKR1C3 AKR1C4 AKR1C2

6.83e-0479453GO:0072577
GeneOntologyBiologicalProcessRNA splicing

AKR1C3 AKR1C4 UPF1 PRPF3 AKR1C2 SF1

7.34e-04502456GO:0008380
GeneOntologyBiologicalProcesscellular response to corticosteroid stimulus

AKR1C3 AKR1C4 AKR1C2

7.35e-0481453GO:0071384
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

AKR1C3 PXN AKR1C4 YES1 AKR1C2

7.97e-04336455GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

AKR1C3 PXN AKR1C4 YES1 AKR1C2

8.74e-04343455GO:0071559
GeneOntologyBiologicalProcesscellular response to calcium ion

AKR1C3 AKR1C4 AKR1C2

9.35e-0488453GO:0071277
GeneOntologyBiologicalProcesspositive regulation of reactive oxygen species metabolic process

AKR1C3 AKR1C4 AKR1C2

9.67e-0489453GO:2000379
GeneOntologyBiologicalProcessnegative regulation of lipid biosynthetic process

AKR1C3 AKR1C4 AKR1C2

1.03e-0391453GO:0051055
GeneOntologyBiologicalProcesssteroid biosynthetic process

AKR1C3 AKR1C4 AKR1C2 SF1

1.10e-03209454GO:0006694
GeneOntologyBiologicalProcessmRNA processing

AKR1C3 AKR1C4 UPF1 PRPF3 AKR1C2 SF1

1.19e-03551456GO:0006397
GeneOntologyBiologicalProcessglycosyl compound metabolic process

AKR1C3 AKR1C4 AKR1C2

1.20e-0396453GO:1901657
GeneOntologyBiologicalProcessresponse to estrogen

AKR1C3 AKR1C4 AKR1C2

1.47e-03103453GO:0043627
GeneOntologyBiologicalProcessregulation of lipid biosynthetic process

AKR1C3 AKR1C4 AKR1C2 SF1

2.00e-03246454GO:0046890
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

AKR1C3 AKR1C4 AKR1C2

2.02e-03115453GO:1903312
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

AKR1C3 AKR1C4 UPF1 AKR1C2 SF1

2.69e-03443455GO:1903311
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2

1.62e-049452GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2

2.46e-0411452GO:0031094
MousePhenoparturition failure

AKR1C3 AKR1C4 AKR1C2

1.86e-0610363MP:0012010
MousePhenohypermyelination

AKR1C3 AKR1C4 AKR1C2

2.55e-0611363MP:0010050
MousePhenoincreased oligodendrocyte number

AKR1C3 AKR1C4 AKR1C2

4.41e-0613363MP:0010160
MousePhenolong gestation period

AKR1C3 AKR1C4 AKR1C2

6.99e-0615363MP:0002293
MousePhenoincreased circulating progesterone level

AKR1C3 AKR1C4 AKR1C2

6.99e-0615363MP:0005186
MousePhenolong stride length

AKR1C3 AKR1C4 AKR1C2

6.99e-0615363MP:0010540
MousePhenoabnormal gestational length

AKR1C3 AKR1C4 AKR1C2

1.25e-0518363MP:0002292
MousePhenodysmyelination

AKR1C3 AKR1C4 AKR1C2

1.74e-0520363MP:0013438
MousePhenodecreased oligodendrocyte number

AKR1C3 AKR1C4 AKR1C2

3.47e-0525363MP:0009808
MousePhenoprolonged diestrus

AKR1C3 AKR1C4 AKR1C2

6.07e-0530363MP:0009011
MousePhenoabnormal parturition

AKR1C3 AKR1C4 AKR1C2

8.12e-0533363MP:0002907
MousePhenoabnormal diestrus

AKR1C3 AKR1C4 AKR1C2

9.70e-0535363MP:0009010
MousePhenoembryonic lethality prior to tooth bud stage

PAXIP1 ESCO2 EHBP1 FGF8 AP2M1 UPF1 MCM10 SPOUT1 PRPF3 SF1 TOP3A RAD9A

1.10e-0413833612MP:0013293
MousePhenoenhanced coordination

AKR1C3 AKR1C4 AKR1C2

1.24e-0438363MP:0003858
MousePhenoprolonged estrous cycle

AKR1C3 AKR1C4 AKR1C2

1.35e-0439363MP:0009006
MousePhenodecreased vocalization

AKR1C3 AKR1C4 AKR1C2

2.21e-0446363MP:0020351
MousePhenoabnormal somite development

PAXIP1 RPL10A PXN FGF8 RAD9A

2.44e-04222365MP:0001688
MousePhenoabnormal amnion morphology

PAXIP1 PXN FGF8

2.51e-0448363MP:0005029
MousePhenoabnormal circulating progesterone level

AKR1C3 AKR1C4 AKR1C2

2.83e-0450363MP:0005184
MousePhenoabnormal oligodendrocyte morphology

AKR1C3 AKR1C4 AKR1C2

3.00e-0451363MP:0000953
MousePhenoincreased stereotypic behavior

AKR1C3 AKR1C4 AKR1C2

3.36e-0453363MP:0001409
MousePhenoabnormal progesterone level

AKR1C3 AKR1C4 AKR1C2

3.55e-0454363MP:0011384
MousePhenoembryonic lethality prior to organogenesis, complete penetrance

PAXIP1 ESCO2 AP2M1 UPF1 MCM10 SPOUT1 SF1 TOP3A

6.34e-04772368MP:0014259
MousePhenoembryonic lethality prior to tooth bud stage, complete penetrance

PAXIP1 ESCO2 AP2M1 UPF1 MCM10 SPOUT1 SF1 TOP3A

6.73e-04779368MP:0014257
MousePhenoabnormal stride length

AKR1C3 AKR1C4 AKR1C2

1.21e-0382363MP:0012690
DomainALDOKETO_REDUCTASE_1

AKR1C3 AKR1C4 AKR1C2

1.17e-0610413PS00798
DomainAldo/ket_reductase_CS

AKR1C3 AKR1C4 AKR1C2

1.17e-0610413IPR018170
DomainAldo/keto_reductase

AKR1C3 AKR1C4 AKR1C2

1.17e-0610413IPR020471
DomainALDOKETO_REDUCTASE_2

AKR1C3 AKR1C4 AKR1C2

1.17e-0610413PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C3 AKR1C4 AKR1C2

1.17e-0610413PS00063
Domain-

AKR1C3 AKR1C4 AKR1C2

5.39e-06164133.20.20.100
DomainNADP_OxRdtase_dom

AKR1C3 AKR1C4 AKR1C2

6.54e-0617413IPR023210
DomainAldo_ket_red

AKR1C3 AKR1C4 AKR1C2

6.54e-0617413PF00248
DomainAldo/ket_red/Kv-b

AKR1C3 AKR1C4 AKR1C2

6.54e-0617413IPR001395
DomainInsP3_rcpt-bd

ITPR1 ITPR2

1.41e-053412IPR000493
DomainRIH_assoc

ITPR1 ITPR2

7.01e-056412PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2

7.01e-056412IPR013662
DomainRYDR_ITPR

ITPR1 ITPR2

7.01e-056412PF01365
DomainRIH_dom

ITPR1 ITPR2

7.01e-056412IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2

7.01e-056412IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2

7.01e-056412IPR015925
DomainIns145_P3_rec

ITPR1 ITPR2

7.01e-056412PF08709
Domain-

ITPR1 ITPR2

7.01e-0564121.25.10.30
DomainMIR

ITPR1 ITPR2

2.09e-0410412PS50919
DomainMIR

ITPR1 ITPR2

2.09e-0410412PF02815
DomainMIR

ITPR1 ITPR2

2.09e-0410412SM00472
DomainMIR_motif

ITPR1 ITPR2

2.09e-0410412IPR016093
DomainARM-type_fold

DOCK2 ARMC9 ITPR1 ITPR2

6.36e-03339414IPR016024
DomainZnF_C2HC

SF1 TOP3A

6.49e-0355412SM00343
DomainZnf_CCHC

SF1 TOP3A

6.49e-0355412IPR001878
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C3 AKR1C4 AKR1C2 ADH4

4.90e-0728334MM15188
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C3 AKR1C4 AKR1C2

9.72e-079333M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C3 AKR1C4 AKR1C2

9.72e-079333M47817
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C3 AKR1C4 AKR1C2

1.90e-0611333M47812
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C2

3.29e-0613333M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C2

3.29e-0613333MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C3 AKR1C4 AKR1C2

4.18e-0614333M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C2

4.18e-0614333M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C3 AKR1C4 AKR1C2

4.18e-0614333M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C2

4.18e-0614333MM14748
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

AKR1C3 AKR1C4 AKR1C2 ADH4

4.89e-0649334MM15186
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C3 AKR1C4 AKR1C2

5.22e-0615333MM14870
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C2

2.00e-0523333M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C3 AKR1C4 AKR1C2

2.00e-0523333MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C2

2.00e-0523333MM14741
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

AKR1C3 AKR1C4 AKR1C2 ADH4

2.05e-0570334M16794
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2

5.29e-055332M49000
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C3 AKR1C4 AKR1C2

6.08e-0533333M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C3 AKR1C4 AKR1C2

6.08e-0533333MM14737
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

7.92e-056332M47960
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C3 AKR1C4 AKR1C2

1.45e-0444333M499
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C3 AKR1C4 AKR1C2

1.55e-0445333MM15344
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C3 AKR1C4 AKR1C2

1.55e-0445333MM14751
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

1.89e-049332M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

2.36e-0410332M47661
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

FGF8 ITPR1 ITPR2

2.82e-0455333M47952
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

AKR1C3 AKR1C4 AKR1C2

2.82e-0455333M14933
PathwayWP_ALTERNATIVE_PATHWAY_OF_FETAL_ANDROGEN_SYNTHESIS

AKR1C4 AKR1C2

2.88e-0411332M39749
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

2.88e-0411332M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2

2.88e-0411332M27466
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

AKR1C3 AKR1C4 AKR1C2

3.83e-0461333MM14861
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

4.08e-0413332M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

4.08e-0413332M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

4.08e-0413332M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2

4.08e-0413332MM14553
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2

6.25e-0416332M26945
PathwayWP_MFAP5_EFFECT_ON_PERMEABILITY_AND_MOTILITY_OF_ENDOTHELIAL_CELLS_VIA_CYTOSKELETON_REARRANGEMENT

PXN ITPR1

7.94e-0418332M39808
PathwayWP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR

UPF1 TOP3A RAD9A

8.81e-0481333M39490
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2

8.86e-0419332M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

8.86e-0419332M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

8.86e-0419332M47733
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

AKR1C3 AKR1C4 AKR1C2 ADH4

9.83e-04191334MM15586
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

9.83e-0420332M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

1.09e-0321332M47689
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C3 ADH4

1.19e-0322332M27445
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

1.19e-0322332M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

1.19e-0322332M47675
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

AKR1C3 AKR1C4 AKR1C2

1.27e-0392333MM14881
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

1.30e-0323332M47676
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

PXN FGF8 AP2M1 YES1 ITPR1 ITPR2

1.30e-03532336M27870
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

YES1 ITPR1 ITPR2

1.40e-0395333M29842
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2

1.54e-0325332MM14511
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2

1.80e-0327332MM15053
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2

1.80e-0327332M12123
PathwayREACTOME_SIGNALING_BY_VEGF

PXN ITPR1 ITPR2

1.91e-03106333M27077
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2

1.93e-0328332M924
PathwayREACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS

DOCK2 AP2M1

1.93e-0328332M11362
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2

2.52e-0332332MM14983
PathwayREACTOME_DRUG_ADME

AKR1C3 AKR1C4 AKR1C2

2.66e-03119333MM15692
PathwayPID_ATM_PATHWAY

TOP3A RAD9A

2.84e-0334332M84
PathwayREACTOME_INFECTIOUS_DISEASE

RPL10A MED14 DOCK2 AP2M1 YES1 CHMP2B ITPR1 ITPR2

2.87e-031081338M27548
PathwayREACTOME_METABOLISM_OF_STEROIDS

AKR1C3 AKR1C4 AKR1C2

3.13e-03126333MM15553
PathwayREACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA

TOP3A RAD9A

3.19e-0336332MM15281
PathwayREACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS

MCM10 RAD9A

3.19e-0336332MM14687
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

ITPR1 ITPR2

3.19e-0336332M1315
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

ITPR1 ITPR2

3.19e-0336332M39831
PathwayREACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS

MCM10 RAD9A

3.36e-0337332M11153
PathwayREACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA

TOP3A RAD9A

3.36e-0337332M27568
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

YES1 ITPR1 ITPR2

3.72e-03134333M29840
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ITPR1 ITPR2

4.12e-0341332M512
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2

4.32e-0342332M791
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

YES1 ITPR1 ITPR2

4.46e-03143333M27107
PathwayREACTOME_G2_M_CHECKPOINTS

MCM10 TOP3A RAD9A

4.46e-03143333MM15383
PathwayREACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE

TOP3A RAD9A

4.52e-0343332M27588
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

AKR1C3 ADH4

4.52e-0343332M27443
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

ITPR1 ITPR2

4.73e-0344332M39845
PathwayREACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR

PAXIP1 TOP3A RAD9A

4.73e-03146333MM15292
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

AP2M1 ITPR1 ITPR2

4.73e-03146333M27288
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

AKR1C3 AKR1C2

4.94e-0345332M39355
PathwaySIG_CHEMOTAXIS

ITPR1 ITPR2

4.94e-0345332M5193
PathwaySIG_BCR_SIGNALING_PATHWAY

ITPR1 ITPR2

5.16e-0346332M8626
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

AKR1C3 AKR1C4 AKR1C2 SF1

1.20e-091245428893949
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445320124700
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445310702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445317034817
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C3 AKR1C4 AKR1C2

8.09e-09445310500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445316508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445319487289
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445317629694
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445314967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445310393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445315193432
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445329764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445310526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445317888864
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445331479646
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445317442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445328329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445316018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445317272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445319237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445318667791
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445315222881
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445328259989
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445316191478
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445321521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4 AKR1C2

8.09e-0944538274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445316511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445310803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445334590152
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C3 AKR1C4 AKR1C2

8.09e-09445315577209
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C3 AKR1C4 AKR1C2

8.09e-0944537789999
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C3 AKR1C4 AKR1C2

2.02e-0854537737980
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545310672042
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545321851338
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545338788959
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545317872381
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545316984997
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545317064890
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C3 AKR1C4 AKR1C2

2.02e-08545318003893
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL10A MED14 AP2M1 UPF1 MCM10 DNAJC10 SPOUT1 PRPF3 SMCHD1 CHMP2B

3.70e-08759451035915203
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645329107092
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645326748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645317122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645317255200
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645319273550
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645315860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4 AKR1C2

4.04e-08645315471942
Pubmed

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.

AKR1C3 AKR1C4 AKR1C2 SF1

4.89e-082845429879378
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C3 AKR1C4 AKR1C2

7.06e-08745334843575
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C3 AKR1C4 AKR1C2

7.06e-08745322529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C3 AKR1C4 AKR1C2

7.06e-08745333127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C3 AKR1C4 AKR1C2

7.06e-08745312562828
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C3 AKR1C4 AKR1C2

7.06e-08745326160177
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C3 AKR1C4 AKR1C2

7.06e-08745316337335
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C3 AKR1C4 AKR1C2

1.13e-07845320837989
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C3 AKR1C4 AKR1C2

1.13e-07845333584538
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C3 AKR1C4 AKR1C2

1.13e-0784539224647
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C3 AKR1C4 AKR1C2

1.69e-07945333348080
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C3 AKR1C4 AKR1C2

2.41e-071045336313771
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

AKR1C3 AKR1C4 AKR1C2

4.42e-071245321256921
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

AKR1C3 AKR1C4 AKR1C2

4.42e-071245325774556
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C3 AKR1C4 AKR1C2

5.74e-071345315117747
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C3 AKR1C4 AKR1C2

5.74e-071345311682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C3 AKR1C4 AKR1C2

5.74e-071345317062636
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

AKR1C3 AKR1C4 AKR1C2

5.74e-071345324580729
Pubmed

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.

AKR1C3 AKR1C4 AKR1C2

7.29e-071445319955443
Pubmed

Placental endocrine function shapes cerebellar development and social behavior.

AKR1C3 AKR1C4 AKR1C2

7.29e-071445334400844
Pubmed

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.

AKR1C3 AKR1C4 AKR1C2

1.36e-061745332243503
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

RPL10A MED14 UPF1 DNAJC10 PRPF3 ITPR1 ITPR2

1.48e-0644045734244565
Pubmed

Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.

AKR1C3 AKR1C4

1.64e-0624527650035
Pubmed

Local androgen inactivation in abdominal visceral adipose tissue.

AKR1C3 AKR1C2

1.64e-06245214671194
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

1.64e-06245219120126
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

1.64e-06245218708078
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

1.64e-06245215201137
Pubmed

AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants.

AKR1C3 AKR1C2

1.64e-06245233675863
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

1.64e-06245223582047
Pubmed

Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase.

AKR1C4 AKR1C2

1.64e-0624522187532
Pubmed

Functional dynamics of H3K9 methylation during meiotic prophase progression.

AKR1C3 AKR1C4 AKR1C2

1.93e-061945317599069
Pubmed

A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.

AKR1C3 AKR1C4 AKR1C2

2.27e-062045323636947
Pubmed

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

AKR1C3 AKR1C4 AKR1C2

2.27e-062045324135228
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RPL10A EHBP1 PRR14L AP2M1 UPF1 PRPF3 SF1 SMCHD1 CHMP2B

2.60e-0693445933916271
Pubmed

Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.

AKR1C3 AKR1C4 AKR1C2

3.52e-062345323685333
Pubmed

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

AKR1C3 AKR1C4 AKR1C2

4.56e-062545326098214
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C3 AKR1C2

4.91e-06345219320734
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2

4.91e-06345231979185
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2

4.91e-06345210874040
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2

4.91e-0634529808793
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2

4.91e-06345224904548
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2

4.91e-06345220395455
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C3 AKR1C2

4.91e-06345231780644
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

4.91e-06345217327232
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2

4.91e-06345217437169
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

ITPR1 ITPR2

4.91e-06345223223241
Pubmed

Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.

AKR1C3 AKR1C4

4.91e-0634527626489
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C3 AKR1C2

4.91e-06345221232532
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2

4.91e-06345216014380
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C3 AKR1C2

4.91e-06345213678667
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2

4.91e-06345218194433
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2

4.91e-06345217890015
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2

4.91e-06345218547250
InteractionAKR1C4 interactions

AKR1C3 AKR1C4 AKR1C2

5.40e-078443int:AKR1C4
InteractionZBTB8A interactions

PAXIP1 AP2M1 MCM10 YES1 PRPF3

8.89e-0781445int:ZBTB8A
InteractionAKR1C1 interactions

AKR1C3 AKR1C4 AKR1C2

1.08e-0520443int:AKR1C1
InteractionHECTD1 interactions

RPL10A MED14 AP2M1 UPF1 MCM10 DNAJC10 SPOUT1 PRPF3 SMCHD1 CHMP2B

4.00e-059844410int:HECTD1
InteractionZBTB8B interactions

PAXIP1 AP2M1 MCM10

5.54e-0534443int:ZBTB8B
InteractionSIRT6 interactions

RPL10A MED14 UPF1 DNAJC10 PRPF3 RAD9A ITPR1 ITPR2

5.59e-05628448int:SIRT6
InteractionBRCA1 interactions

RPL10A HLTF MMS22L UPF1 MCM10 DNAJC10 PRPF3 SMCHD1 TOP3A RAD9A ITPR1

5.70e-0512494411int:BRCA1
InteractionAKR1C3 interactions

AKR1C3 AKR1C4 AKR1C2

7.16e-0537443int:AKR1C3
InteractionHERC2 interactions

MED14 PRR14L UPF1 SPOUT1 CCDC136 TOP3A ITPR2

9.96e-05503447int:HERC2
InteractionPAK2 interactions

DOCK2 PXN AP2M1 RHOJ YES1

1.04e-04216445int:PAK2
InteractionH3C1 interactions

PAXIP1 ESCO2 RPL10A MED14 PXN MMS22L PRR14L PRPF3 SMCHD1

1.18e-04901449int:H3C1
Cytoband10p15-p14

AKR1C3 AKR1C2

1.41e-05645210p15-p14
CytobandEnsembl 112 genes in cytogenetic band chr10p15

AKR1C3 AKR1C4 AKR1C2

9.74e-0590453chr10p15
GeneFamilyAldo-keto reductases

AKR1C3 AKR1C4 AKR1C2

2.26e-0615323399
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2

9.09e-063322297
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C3 AKR1C4 ST3GAL6 AKR1C2

7.85e-0824454MM766
CoexpressionWANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP

AKR1C3 AKR1C4 RHOJ AKR1C2

4.80e-0737454MM630
CoexpressionGSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN

EHBP1 PABPC4L CLDN7 CCDC66 MAN2A2 CCDC136

1.16e-06200456M7495
CoexpressionDARWICHE_PAPILLOMA_RISK_HIGH_DN

AKR1C3 ARMC9 AKR1C4 MAN2A2 AKR1C2 ITPR1

1.20e-06201456MM500
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C3 AKR1C4 AKR1C2

3.16e-0617453MM826
CoexpressionMARSON_FOXP3_TARGETS_DN

AKR1C3 GPR171 AKR1C4 AKR1C2

3.45e-0660454MM847
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_UP

ESCO2 AKR1C3 AKR1C4 ADAMTS4 AKR1C2

5.83e-06150455MM936
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D

AKR1C3 AKR1C4 DNAJC10 PRPF3 AKR1C2 ITPR2

1.05e-05293456MM895
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C3 AKR1C4 AKR1C2

1.06e-0525453MM480
CoexpressionHOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN

AKR1C3 AKR1C4 ST3GAL6 AKR1C2

1.39e-0585454MM802
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

AKR1C3 AKR1C4 MCM10 AKR1C2 ADH4

1.83e-05190455MM1311
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS

AKR1C3 AKR1C4 AKR1C2

1.86e-0530453MM853
CoexpressionZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL

RPL10A AKR1C3 AKR1C4 TBRG1 RHOJ AKR1C2

2.31e-05337456MM16606
CoexpressionGSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP

DOCK2 PXN MAN2A2 DNAJC10 SMCHD1

2.35e-05200455M9895
CoexpressionDARWICHE_SQUAMOUS_CELL_CARCINOMA_DN

AKR1C3 ARMC9 AKR1C4 AKR1C2 ITPR1

2.40e-05201455MM502
CoexpressionMATSUDA_NATURAL_KILLER_DIFFERENTIATION

AKR1C3 AKR1C4 UPF1 ST3GAL6 SLC15A1 YES1 AKR1C2

2.74e-05520457MM1008
CoexpressionDESCARTES_ORGANOGENESIS_INTERMEDIATE_MESODERM

AKR1C3 AKR1C4 AKR1C2

3.24e-0536453MM3660
CoexpressionDARWICHE_SKIN_TUMOR_PROMOTER_DN

AKR1C3 ARMC9 AKR1C4 AKR1C2 ITPR1

4.12e-05225455MM496
CoexpressionVARELA_ZMPSTE24_TARGETS_DN

AKR1C3 AKR1C4 AKR1C2

6.38e-0545453MM1173
CoexpressionMCBRYAN_PUBERTAL_BREAST_5_6WK_UP

AKR1C3 AKR1C4 CLDN7 AKR1C2

1.06e-04143454MM989
CoexpressionNFE2L2.V2

ESCO2 AKR1C3 AKR1C4 MCM10 SLC15A1 SF1

1.43e-04469456M2870
CoexpressionNADLER_HYPERGLYCEMIA_AT_OBESITY

AKR1C3 AKR1C4 AKR1C2

2.01e-0466453MM631
CoexpressionFISCHER_DREAM_TARGETS

ESCO2 HLTF EHBP1 MMS22L MCM10 SMCHD1 TOP3A RAD9A

2.17e-04969458M149
CoexpressionGOLDRATH_IMMUNE_MEMORY

AKR1C3 AKR1C4 AKR1C2

2.29e-0469453MM621
CoexpressionBREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP

AKR1C3 AKR1C4 AKR1C2

2.81e-0474453MM769
CoexpressionDARWICHE_PAPILLOMA_RISK_HIGH_DN

AKR1C3 ARMC9 MAN2A2 ITPR1

2.85e-04185454M1137
CoexpressionDARWICHE_PAPILLOMA_RISK_LOW_UP

AKR1C3 ARMC9 AKR1C4 AKR1C2

3.29e-04192454MM497
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3

AKR1C3 AKR1C4 AKR1C2

3.41e-0479453MM535
CoexpressionGSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN

HLTF TOP3A CFAP46 ITPR1

3.76e-04199454M6507
CoexpressionGSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN

MMS22L GPR171 MAN2A2 ITPR1

3.76e-04199454M9170
CoexpressionGSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN

PXN MAN2A2 TOP3A RAD9A

3.84e-04200454M9002
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN

AKR1C3 MMS22L GPR171 MCM10

3.84e-04200454M9215
CoexpressionZHANG_UTERUS_C4_MYOFIBROBLAST

AKR1C3 AP2M1 AKR1C4 ADAMTS4 AKR1C2

4.14e-04369455MM16610
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C3 ST3GAL6

4.84e-0419452M1847
CoexpressionZAMORA_NOS2_TARGETS_DN

AKR1C3 AKR1C4 AKR1C2

4.84e-0489453MM690
CoexpressionPUJANA_ATM_PCC_NETWORK

PAXIP1 RPL10A DOCK2 FGF8 GPR171 SLC15A1 SF1 SMCHD1 RAD9A

5.17e-041394459M9585
CoexpressionWANG_RECURRENT_LIVER_CANCER_UP

RPL10A DNAJC10

5.37e-0420452M10922
CoexpressionRAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP

AKR1C3 AKR1C4 SLC15A1 AKR1C2

5.40e-04219454MM1237
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 MMS22L MCM10 TOP3A

2.54e-05169454e7514956b2e4298222ec443f98b2f5289451786e
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ESCO2 MED14 MCM10 TOP3A

2.72e-051724547c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 PABPC4L MCM10 ADAMTS4

3.04e-0517745473ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A GPR171 SMCHD1 ITPR2

3.46e-0518345428cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A GPR171 SMCHD1 ITPR2

3.46e-051834543fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK|GI_small-bowel / Manually curated celltypes from each tissue

ESCO2 AKR1C3 PXN MCM10

3.77e-05187454265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESCO2 DOCK2 MMS22L MCM10

4.09e-05191454bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PXN ADAMTS4 RHOJ YES1

4.26e-05193454479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PXN ADAMTS4 RHOJ SMCHD1

4.44e-05195454a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

ESCO2 DOCK2 GPR171 MCM10

4.44e-051954547e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PXN ADAMTS4 RHOJ YES1

4.44e-05195454818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-MAIT|Liver / Manually curated celltypes from each tissue

GPR171 AKR1C4 AKR1C2 ADH4

4.44e-051954546da0db2a36a34952daab87d74367b491582dedea
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like|Liver / Manually curated celltypes from each tissue

GPR171 AKR1C4 AKR1C2 ADH4

4.44e-0519545437853fe760eac27ecb2fe42ebff42deca0153400
ToppCellPSB-critical-LOC-Lymphoid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ESCO2 DOCK2 GPR171 MCM10

4.53e-051964547b5c2a4cdea9a944f83bfc2c493d3076c3daaeaa
ToppCellerythropoietic-Polychromatic_Erythroblast|World / Lineage and Cell class

ESCO2 HLTF AKR1C3 MCM10

4.62e-05197454604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCellVE-CD8-CD8_2|VE / Condition, Cell_class and T cell subcluster

RPL10A GPR171 CLDN7 SF1

4.80e-05199454014fff8a0ebfda094a6ad76ddc0131e12a313394
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

AKR1C3 MAN2A2 DNAJC10

4.88e-057045337e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ESCO2 RPL10A EHBP1 MCM10

4.89e-05200454c00cc0b91baa37828895d9d6b8acbc6aa503215a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ESCO2 RPL10A EHBP1 MCM10

4.89e-052004549e1b62a703fb7d413ce580448a1df5127c28e8a7
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD3|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 PABPC4L FGF8 TRBV23-1

4.89e-052004546b34f2b85d4f83c1270ee151f602cba6f42042ba
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD3-NKT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 PABPC4L FGF8 TRBV23-1

4.89e-05200454b2c5618aa1ac19423996336795dadb39ea57cda7
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Severe / Disease, condition lineage and cell class

RPL10A GPR171 CCDC66 SMCHD1

4.89e-05200454deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCellMild/Remission-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GPR171 ST3GAL6 ADAMTS4

3.96e-04142453fc5fc2d2b4b976358b8ce762c1f440b20db84103
ToppCellMild/Remission-B_naive-5|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GPR171 ST3GAL6 ADAMTS4

4.47e-041484538b60f9843505660b3c9d5c7792976f902be4b94c
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

GPR171 SF1 SMCHD1

4.74e-04151453999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK2 GPR171 ST3GAL6

4.74e-04151453b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

4.93e-04153453d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

4.93e-0415345354a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

4.93e-0415345369a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

4.93e-04153453e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 MMS22L MCM10

5.21e-04156453955547dfeb1b1ad4957b4338701055726b22619f
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 MMS22L CLDN7

5.21e-04156453b28bbdb515317368f1231b0b15d7442352f3b400
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM10 ST3GAL6 YES1

5.21e-041564531928c86deb3bcd01db4ae76919a351066aadb39a
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|368C / Donor, Lineage, Cell class and subclass (all cells)

GPR171 CCDC66 CCDC136

5.51e-041594537065062fce248e0458932a22dfcc25a5b5a70cbd
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR171 ADAMTS4 CCDC136

5.61e-041604531cb6f42b68c9e41e8edae0de8f0d8371c4620b04
ToppCellfacs-Liver-Liver_non-hepato/SCs|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR171 ADAMTS4 CCDC136

5.61e-04160453ebefde92db400cbe68d9ce31545a0308e0afbde1
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SF1 SMCHD1 ITPR1

5.82e-04162453b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 MMS22L MCM10

6.36e-04167453108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 MMS22L MCM10

6.58e-04169453121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

PAXIP1 ESCO2 MCM10

6.69e-041704535319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 MMS22L CCDC66

6.81e-041714531eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 DOCK2 MCM10

6.92e-04172453ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellNS-critical-d_16-33-Epithelial-Basal|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPL10A AKR1C3 AKR1C2

7.04e-041734533d3afc9ab234eaabf5b9bff455406231cd54ded6
ToppCell10x5'-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

ESCO2 AKR1C3 MCM10

7.04e-04173453d815832f89f70662706620e3b03ebb1dabec0034
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Neutrophil|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 FGF8 SMCHD1

7.04e-04173453dfa56753319c92ae5b337793c4d6d5f70afce546
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 DOCK2 GPR171

7.16e-041744537b318796728001c17b4043d2b033330c7be40c78
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HLTF MMS22L MCM10

7.16e-0417445309b091e24317c3f7bac043f04762a533e30793de
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 MMS22L TOP3A

7.28e-041754533bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMS22L MCM10 RHOJ

7.40e-041764533766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

7.40e-04176453d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESCO2 MMS22L MCM10

7.40e-04176453581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PAXIP1 ESCO2 MCM10

7.40e-041764538813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1|Striatum / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

7.40e-04176453a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMS22L MCM10 RHOJ

7.40e-04176453aa1bada2175d8370fc71939a607407155259d195
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 SMCHD1 ITPR1

7.52e-04177453f54691e5558091c1734ab15153a10bff15ed171e
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK2 SMCHD1 ITPR1

7.52e-04177453653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARMC9 MCM10 TOP3A

7.52e-04177453e1e45956887371b1c18f1eb479dd930031497520
ToppCellNS-moderate-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ESCO2 MCM10 ADAMTS4

7.52e-04177453174c54acfe19e2bb31418d69e228032ba724cbb6
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 MMS22L MCM10

7.52e-041774538a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 MMS22L MCM10

7.77e-0417945388d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

MED14 GPR171 MAN2A2

7.77e-04179453e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PAXIP1 ESCO2 MCM10

7.77e-04179453e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 MMS22L MCM10

7.77e-0417945380112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL6 SLC15A1 ITPR1

7.90e-04180453a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMS22L ARMC9 MCM10

8.02e-04181453145fae2746c5212640b7b11b04a7759ba8e5c322
ToppCellCOVID-19-kidney-Mito-rich_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 GPR171 SMCHD1

8.02e-041814538448c2ad560cfd48bfe9dc1dd3a64373e6a622dd
ToppCellHSPCs-Erythroblasts|World / Lineage and Cell class

ESCO2 ARMC9 ST3GAL6

8.02e-04181453ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMS22L ARMC9 MCM10

8.02e-04181453a9f1fc5973cffdbeb7d1f5c41534422d85d596ff
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 MMS22L MCM10

8.15e-0418245311494a66d986297b837332ee9d382b71b9f22591
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

ESCO2 CCDC27 MCM10

8.15e-0418245381557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR171 SMCHD1 ITPR2

8.15e-04182453eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKR1C3 RHOJ AKR1C2

8.28e-04183453764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

ESCO2 MMS22L MCM10

8.28e-04183453f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ST3GAL6 ADAMTS4 RHOJ

8.28e-04183453bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESCO2 MMS22L MCM10

8.28e-041834536c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC10 ST3GAL6 ITPR1

8.28e-04183453ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5|Striatum / BrainAtlas - Mouse McCarroll V32

ESCO2 MMS22L MCM10

8.28e-04183453f20b0d71f857ac35868fd80531050ad8b6091716
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC10 ST3GAL6 ITPR1

8.28e-04183453c52b84034503d931f7b87312d2ff86daff14152d
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMC9 CLDN7 CCDC136

8.42e-04184453204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

EHBP1 MMS22L TOP3A

8.42e-041844530e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMC9 CLDN7 CCDC136

8.42e-041844539365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESCO2 MMS22L MCM10

8.55e-0418545347c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PXN ADAMTS4 YES1

8.55e-04185453673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

EHBP1 MMS22L TOP3A

8.55e-041854531979d189c204f4c2893e3170a514ee7d5523406c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 GPR171 SMCHD1

8.68e-041864539d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 GPR171 SMCHD1

8.68e-04186453bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MMS22L SMCHD1 ITPR2

8.68e-041864538571956890fc9894d766ba294a28e376b4aba428
ToppCellNasal_Brush-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

AKR1C3 PXN AKR1C2

8.68e-04186453f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 GPR171 SMCHD1

8.68e-04186453924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 PABPC4L MCM10

8.82e-04187453a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 PABPC4L MCM10

8.82e-0418745338ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 PABPC4L MCM10

8.82e-04187453dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

DNAJC10 SMCHD1 ITPR1

8.95e-04188453ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellCalu_3-infected-SARSCoV1|infected / Cell line, Condition and Strain

RPL10A PXN AP2M1

8.95e-04188453a689d59555ecf10bf88c886197d4f7bf9be6c586
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESCO2 MMS22L MCM10

8.95e-041884530ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCellCOVID-19-kidney-T-cells-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 MMS22L GPR171

8.95e-0418845315484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 MMS22L MCM10

8.95e-0418845361ae7405ab56570409bf35382dc0a038e4137c15
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GPR171 CCDC66 SMCHD1

8.95e-04188453e5c480b9a030536578f1cc91fb61738f752525b3
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKR1C3 RHOJ ITPR2

9.09e-041894537346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 MMS22L MCM10

9.09e-04189453bfa3ed1360991a3e32fad133017c413f8adc1eba
DrugPregnanes

AKR1C3 AKR1C4 AKR1C2

2.69e-084443ctd:D011278
Drugtetralol

AKR1C3 AKR1C4 AKR1C2

2.69e-084443ctd:C019106
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C3 AKR1C4 AKR1C2

2.69e-084443ctd:C018156
Drugcloxazolam

AKR1C3 AKR1C4 AKR1C2

2.69e-084443ctd:C005522
DrugHydroxysteroids

AKR1C3 AKR1C4 AKR1C2

6.72e-085443ctd:D006914
Drugcresolphthalein

AKR1C3 AKR1C4 AKR1C2

6.72e-085443ctd:C010092
DrugMedazepam

AKR1C3 AKR1C4 AKR1C2

1.34e-076443ctd:D008472
Drug3-hydroxyhexobarbital

AKR1C3 AKR1C4 AKR1C2

1.34e-076443CID000439898
Drug2-cyclohexen-1-ol

AKR1C3 AKR1C4 AKR1C2

3.75e-078443CID000013198
DrugNitrazepam

AKR1C3 AKR1C4 AKR1C2

3.75e-078443ctd:D009567
Drug4-hydroxybenzoic acid

AKR1C3 AKR1C4 AKR1C2

5.61e-079443ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C3 AKR1C4 AKR1C2

5.61e-079443ctd:D004092
Drugoctyl gallate

AKR1C3 AKR1C4 AKR1C2

8.00e-0710443ctd:C016627
DrugDihydroxydihydrobenzopyrenes

AKR1C3 AKR1C4 AKR1C2

1.10e-0611443ctd:D004101
Drugchlordecone alcohol

AKR1C3 AKR1C4 AKR1C2

1.10e-0611443CID000013946
DrugPhenolphthalein

AKR1C3 AKR1C4 AKR1C2

1.46e-0612443ctd:D020113
DrugDMBA-3,4-dihydrodiol

AKR1C3 AKR1C4 AKR1C2

1.90e-0613443CID000050096
Drugflunisolide

AKR1C3 AKR1C4 AKR1C2

1.90e-0613443ctd:C007734
Drug1-acenaphthenol

AKR1C3 AKR1C4 AKR1C2

2.41e-0614443CID000022750
Drug5-alpha-Dihydroprogesterone

AKR1C3 AKR1C4 AKR1C2

2.41e-0614443ctd:D043582
DrugMeclofenamic Acid

AKR1C3 AKR1C4 AKR1C2

2.41e-0614443ctd:D008469
Drugandrostane-3,17-dione

AKR1C3 ARMC9 AKR1C4 AKR1C2

2.84e-0651444CID000000443
DrugMC_MO

AKR1C3 PMP2

3.65e-062442CID000026787
Drugbaccharin

AKR1C3 AKR1C2

3.65e-062442ctd:C012764
Drugoxcarbazepine

AKR1C3 AKR1C4 AKR1C2

6.39e-0619443ctd:C036006
Drugbenzo(a)pyrene-7,8-dione

AKR1C3 AKR1C4 AKR1C2

7.50e-0620443ctd:C076588
DrugChrysenes

AKR1C3 AKR1C4 AKR1C2

7.50e-0620443ctd:D002911
DrugFlunitrazepam

AKR1C3 AKR1C4 AKR1C2

8.74e-0621443ctd:D005445
Drugbenzene dihydrodiol

AKR1C3 AKR1C4 AKR1C2

1.01e-0522443CID000000418
Drugvalganciclovir

UPF1 SLC15A1 RHOJ

1.01e-0522443CID000064147
Drugcyclopentanone

AKR1C3 AKR1C2

1.09e-053442ctd:C007201
Drug5-dihydrodeoxycorticosterone

AKR1C4 AKR1C2

1.09e-053442ctd:C454687
Drug4-benzoylbenzoic acid

AKR1C3 AKR1C2

1.09e-053442ctd:C058818
Drugcyclopentanol

AKR1C3 AKR1C2

1.09e-053442ctd:C016327
Drugdichloro(4-cymene)ruthenium(II)

AKR1C3 AKR1C2

1.09e-053442ctd:C530610
Drug5 beta-pregnane-3,20-dione

AKR1C3 AKR1C4 AKR1C2 PMP2

1.13e-0572444CID000092745
DrugGlycyrrhetinic Acid

AKR1C3 AKR1C4 AKR1C2

1.32e-0524443ctd:D006034
DrugPregnanolone

AKR1C3 AKR1C4 AKR1C2

1.50e-0525443ctd:D011280
Drug9,10-phenanthrenequinone

AKR1C3 AKR1C4 AKR1C2

1.50e-0525443ctd:C005399
Drugglycolithocholic acid

AKR1C3 AKR1C4 AKR1C2

1.70e-0526443CID000115245
Drugtetrahydrodeoxycorticosterone

AKR1C4 AKR1C2

2.18e-054442ctd:C009413
Druggliquidone

AKR1C3 AKR1C2

2.18e-054442ctd:C010969
DrugDBD-H

AKR1C3 AKR1C4

2.18e-054442CID000131382
Drugbenzo(a)pyrene 7,8-dihydrodiol

AKR1C3 AKR1C4 AKR1C2

2.91e-0531443ctd:C017228
DrugAC1MO44G

CLDN7 UPF1 RAD9A PMP2

2.99e-0592444CID003363161
DrugDasatinib

AKR1C3 PXN MMS22L ARMC9 MCM10 YES1 ITPR1

3.37e-05478447ctd:D000069439
DrugNSC86000

AKR1C3 AKR1C2

3.64e-055442CID000257630
Drugfarnesal

AKR1C3 AKR1C2

3.64e-055442ctd:C084519
DrugBenzbromarone

AKR1C3 AP2M1 AKR1C4 ST3GAL6 AKR1C2 ADH4

3.67e-05326446ctd:D001553
Drugterephthalate

ADAMTS4 RHOJ PMP2

4.60e-0536443CID000007489
Drugquercitrin

AP2M1 AKR1C4 AKR1C2

4.60e-0536443CID005280459
Drug4-chloro-m-cresol

AKR1C2 TOP3A ITPR1

5.00e-0537443CID000001732
Drugacacetin

AP2M1 SLC15A1 AKR1C2

5.42e-0538443CID005280442
DrugAC1L93E5

AKR1C3 AKR1C4

5.45e-056442CID000412383
Drugacenaphthene-1-ol

AKR1C3 AKR1C2

5.45e-056442ctd:C023723
DrugEstazolam

AKR1C3 AKR1C2

5.45e-056442ctd:D004949
DrugGlipizide

AKR1C3 AKR1C2

5.45e-056442ctd:D005913
Drug20 alpha-dihydroprogesterone

AKR1C3 AKR1C4 AKR1C2

6.33e-0540443CID000008956
Drugo-quinone

AKR1C3 AKR1C4 AKR1C2

6.82e-0541443CID000011421
Drug4-hydroxyequilenin-o-quinone

AKR1C3 AKR1C2

7.62e-057442ctd:C117714
Drugzomepirac

AKR1C3 AKR1C2

7.62e-057442ctd:C020549
Druggermacrane D

AKR1C2 PMP2

7.62e-057442CID000543807
DrugFlufenamic Acid

AKR1C3 AKR1C4 AKR1C2

9.03e-0545443ctd:D005439
Drugnaphthalene-1,2-dihydrodiol

AKR1C3 AKR1C4 AKR1C2

9.03e-0545443CID000000362
DrugOcta

AKR1C3 FGF8 AKR1C4

1.10e-0448443CID000010213
DrugMOF-5

UPF1 PMP2

1.30e-049442CID000139613
Drug7-azaindole

SLC15A1 AKR1C2 PMP2

1.47e-0453443CID000009222
Drug1H-inden-1-yl

ESCO2 PMP2

1.63e-0410442CID005374393
Drughafnium hydroxide

ESCO2 PMP2

1.63e-0410442CID000082817
DrugHexestrol

AKR1C3 AKR1C4 AKR1C2

1.65e-0455443ctd:D006589
DrugNADH

AKR1C3 AKR1C4 AKR1C2 ADH4

1.71e-04144444DB00157
Drug1,2-dihydroxynaphthalene

AKR1C3 AKR1C4 AKR1C2

1.83e-0457443CID000011318
Drugphenolphthalein

AKR1C3 AKR1C4 AKR1C2

1.93e-0458443CID000004764
DrugNSC36919

AKR1C3 AKR1C4 AKR1C2

1.93e-0458443CID000235496
Drugfenamic acid

AKR1C3 AKR1C2

2.38e-0412442ctd:C001209
Drugellipticine derivative

AKR1C2 TOP3A

2.38e-0412442CID000434612
Drugxestospongin C

ITPR1 ITPR2

2.38e-0412442ctd:C511704
Drug4-formyl-benzoate

AKR1C4 AKR1C2

2.81e-0413442CID000012088
Drugchlordecone

AKR1C3 AKR1C4 AKR1C2

2.96e-0467443CID000000299
DrugDydrogesterone

AKR1C3 AKR1C2

3.27e-0414442ctd:D004394
Drug6-.beta.-Naltrexol

AKR1C4 AKR1C2

3.27e-0414442CID000631219
Drugcoumarin-3-carboxylic acid

SLC15A1 PMP2

3.77e-0415442CID000010752
Drugindenylidene

ESCO2 PMP2

3.77e-0415442CID005460737
Drugdrospirenone

AKR1C4 AKR1C2

3.77e-0415442ctd:C035144
Drugprotoberberine

YES1 TOP3A

3.77e-0415442CID000114943
DrugDiazepam

AKR1C3 AKR1C4 AKR1C2

3.97e-0474443ctd:D003975
Drug9-cis-retinal

AKR1C3 AKR1C4

4.31e-0416442ctd:C031390
Druglead carbonate

ESCO2 RHOJ

4.31e-0416442CID000011727
Drug3-phenoxybenzoic acid

AKR1C3 YES1

4.87e-0417442CID000019539
Drugbenzo(a)pyrene-1,6-quinone

AKR1C3 AKR1C2

4.87e-0417442ctd:C030233
DrugNAD

AKR1C3 AKR1C2 ITPR1

4.99e-0480443ctd:D009243
DrugBudesonide

AKR1C3 AKR1C4 AKR1C2

4.99e-0480443ctd:D019819
DrugIndomethacin [53-86-1]; Down 200; 11.2uM; MCF7; HT_HG-U133A

AKR1C3 PXN ARMC9 TOP3A

5.21e-041934447409_DN
DrugParbendazole [14255-87-9]; Down 200; 16.2uM; PC3; HT_HG-U133A

MED14 ARMC9 ITPR1 ITPR2

5.21e-041934443799_DN
DrugEthopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; PC3; HT_HG-U133A

MED14 TOP3A ITPR1 ITPR2

5.21e-041934446697_DN
DrugFlumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A

EHBP1 UPF1 SF1 ITPR2

5.31e-041944444272_DN
Drug1,10-phenanthroline

AKR1C3 AKR1C4 AKR1C2

5.36e-0482443ctd:C025205
DrugHexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; HL60; HT_HG-U133A

MED14 UPF1 SF1 ITPR2

5.42e-041954442708_DN
DrugAndrostane-3,17-diol

AKR1C4 AKR1C2

5.48e-0418442ctd:D015113
Drug1,3-dichlorobenzene

RHOJ YES1

5.48e-0418442CID000010943
DiseaseMALE PSEUDOHERMAPHRODITISM: DEFICIENCY OF TESTICULAR 17,20-DESMOLASE

AKR1C4 AKR1C2

2.07e-062432C1839840
DiseaseAnoxia of brain

ITPR1 ITPR2

2.07e-062432C0995195
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

2.07e-062432C1140716
Disease46,XY SEX REVERSAL 8

AKR1C4 AKR1C2

2.07e-062432614279
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

2.07e-062432C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

2.07e-062432C1527348
Disease46,XY disorder of sex development due to testicular 17,20-desmolase deficiency

AKR1C4 AKR1C2

2.07e-062432cv:C1839840
Disease46,XY sex reversal 8 (is_implicated_in)

AKR1C4 AKR1C2

2.07e-062432DOID:0111773 (is_implicated_in)
DiseaseNeoplasms, Hormone-Dependent

AKR1C3 AKR1C2

6.22e-063432C0027661
DiseaseAmbiguous Genitalia

AKR1C3 AKR1C2

2.07e-055432C0266362
DiseasePseudohermaphroditism

AKR1C3 AKR1C2

2.07e-055432C0033804
DiseaseHermaphroditism

AKR1C3 AKR1C2

2.07e-055432C0019269
DiseaseIntersex Conditions

AKR1C3 AKR1C2

2.07e-055432C2930618
DiseaseSex Differentiation Disorders

AKR1C3 AKR1C2

2.07e-055432C2930619
Diseasecortolone glucuronide (1) measurement

AKR1C3 AKR1C2

3.10e-056432EFO_0800552
DiseaseDisorders of Sex Development

AKR1C3 AKR1C2

4.34e-057432C0036875
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2

1.36e-0412432DOID:1441 (implicated_via_orthology)
Diseasefree androgen index

AKR1C3 AKR1C4 AKR1C2 SMCHD1 ADH4

2.06e-04374435EFO_0007005
Diseaseobesity (implicated_via_orthology)

ADAMTS4 SLC15A1 ITPR1 ITPR2

2.71e-04215434DOID:9970 (implicated_via_orthology)
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

CHMP2B ITPR2

1.00e-0332432DOID:332 (is_implicated_in)
DiseaseNeoplastic Cell Transformation

AKR1C3 PXN AKR1C2

1.10e-03139433C0007621
DiseaseKidney Neoplasm

ESCO2 HLTF

1.56e-0340432C0022665
DiseaseEndometrioma

MED14 AKR1C3 AKR1C2

1.68e-03161433C0269102
DiseaseEndometriosis

MED14 AKR1C3 AKR1C2

1.68e-03161433C0014175

Protein segments in the cluster

PeptideGeneStartEntry
MEKCKDAGLAKSIGV

AKR1C4

151

P17516
MGTKGKVIKCKAAIA

ADH4

1

P08319
MEKCKDAGLAKSIGV

AKR1C3

151

P42330
AKGKVQAVGGSCKVM

CFAP46

2196

Q8IYW2
IKKMAKIGNKEACKV

CHMP2B

46

Q9UQN3
KMQLKCLLKGKGQET

CCDC27

266

Q2M243
MKCLVTGGNVKVLGK

RAD9A

1

Q99638
IVKADGKYVKKCQDM

ITPR2

1316

Q14571
MKAIVECAGGKVLSK

PAXIP1

991

Q6ZW49
VKAEGKFIKKCQDMV

ITPR1

1326

Q14643
CILAKVVKKAMKSNG

MMS22L

486

Q6ZRQ5
TGKNMCAKVAGLVLK

ARMC9

491

Q7Z3E5
DIKEKSNVGCMEFKK

GPR171

156

O14626
MGEALDLGTCKAKKK

MCM10

381

Q7L590
SGVQVICMKGKAKYK

AP2M1

331

Q96CW1
NDEKKMLKCVVVGDG

RHOJ

16

Q9H4E5
KKTKRAGEMCAFNKV

MED14

626

O60244
CKKPIAGQVVTAMGK

PXN

361

P49023
QLGPVVMCKKAAKAG

UPF1

676

Q92900
ICMNKKGKLIAKSNG

FGF8

126

P55075
IGSKKKFDKCMVCGG

ADAMTS4

666

O75173
RVGKMDLKDTGAKKC

DOCK2

301

Q92608
ISVKMGNKAKIAKCP

CCDC66

31

A2RUB6
QNKGKMAKKEEKCVL

EHBP1

1216

Q8NDI1
IVTEKMQGKPVCSKK

ESCO2

121

Q56NI9
MKLKKQVTVCGAAIF

MAN2A2

1

P49641
TKKKMLKKGACAVEG

HLTF

451

Q14527
MIKGKVKAGKVDCQA

DNAJC10

716

Q8IXB1
NIMGKVAKCIGFAIK

SLC15A1

231

P46059
FVNCGMKKEVKIDKN

SPOUT1

206

Q5T280
VTAALNCVGKGMDKK

PRPF3

31

O43395
NCVGKGMDKKKAADH

PRPF3

36

O43395
KKCNLKGAFVKMSGC

PRR14L

1031

Q5THK1
EMNGKLLKGCKVFVG

PABPC4L

156

P0CB38
LKCEMKGGKTVQMGQ

SMCHD1

1151

A6NHR9
KKCVVVGNGGVLKNK

ST3GAL6

116

Q9Y274
MEKCKDAGLAKSIGV

AKR1C2

151

P52895
ANGVKMKKVTKPCSD

CCDC136

991

Q96JN2
GMKCTRCGGDDKVKK

CLDN7

101

O95471
VKGKGQKTKMDCTPE

TRBV23-1

31

A0A0A0MS06
KFQMKKVLCLAVAVG

RPL10A

156

P62906
CNKDMVLKTKKNGGF

TOP3A

661

Q13472
CNAKIMIRGKGSVKE

SF1

171

Q15637
TCKKKKMAGGARKLV

TBRG1

156

Q3YBR2
MGCIKSKENKSPAIK

YES1

1

P07947
NGKMVAECKMKGVVC

PMP2

111

P02689