Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone binding	SART3 TDRD3 CHD3 CHD4 BAZ2A HDGFL2 CHD5	1.02e-06	265	41	7	GO:0042393
GeneOntologyMolecularFunction	molecular adaptor activity	ZSWIM8 TDRD3 DLGAP3 KAT2B ELK1 CHD4 FBXL19 PSIP1 GAS2L3 BAZ2A HDGFL2 PBXIP1 MED12	1.80e-06	1356	41	13	GO:0060090
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	AHR SETD1A KAT2B ELK1 CHD4 PSIP1 BAZ2A PBXIP1 MED12	2.17e-06	582	41	9	GO:0140297
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	ZSWIM8 TDRD3 KAT2B ELK1 CHD4 FBXL19 PSIP1 GAS2L3 BAZ2A HDGFL2 PBXIP1 MED12	2.29e-06	1160	41	12	GO:0030674
GeneOntologyMolecularFunction	transcription coregulator activity	TDRD3 KAT2B ELK1 CHD4 FBXL19 PSIP1 PBXIP1 MED12	1.58e-05	562	41	8	GO:0003712
GeneOntologyMolecularFunction	transcription factor binding	AHR SETD1A KAT2B ELK1 CHD4 PSIP1 BAZ2A PBXIP1 MED12	1.74e-05	753	41	9	GO:0008134
GeneOntologyMolecularFunction	transcription coactivator activity	TDRD3 KAT2B ELK1 PSIP1 PBXIP1 MED12	3.34e-05	303	41	6	GO:0003713
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	HDGFL2 CHD5	4.10e-05	5	41	2	GO:0061628
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD3 CHD4 CHD5	5.95e-05	37	41	3	GO:0140658
GeneOntologyMolecularFunction	chromatin binding	TDRD3 KAT2B ELK1 CHD3 CHD4 PSIP1 MED12 CHD5	1.10e-04	739	41	8	GO:0003682
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	AHR SETD1A ELK1 CHD4 BAZ2A MED12	1.94e-04	417	41	6	GO:0061629
GeneOntologyMolecularFunction	histone deacetylase binding	KAT2B PKN2 CHD4 CHD5	2.31e-04	147	41	4	GO:0042826
GeneOntologyMolecularFunction	U6 snRNA binding	SART3 LARP7	6.16e-04	18	41	2	GO:0017070
GeneOntologyMolecularFunction	methylated histone binding	TDRD3 HDGFL2 CHD5	7.31e-04	86	41	3	GO:0035064
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A SETBP1	7.63e-04	20	41	2	GO:0042800
GeneOntologyMolecularFunction	methylation-dependent protein binding	TDRD3 HDGFL2 CHD5	7.81e-04	88	41	3	GO:0140034
GeneOntologyMolecularFunction	modification-dependent protein binding	TDRD3 BAZ2A HDGFL2 CHD5	8.26e-04	206	41	4	GO:0140030
GeneOntologyMolecularFunction	histone modifying activity	SETD1A KAT2B FBXL19 SETBP1	1.22e-03	229	41	4	GO:0140993
GeneOntologyMolecularFunction	ATP-dependent activity	IQCA1L CHD3 CHD4 UBA1 ABCF1 CHD5	1.48e-03	614	41	6	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	IQCA1L CHD3 CHD4 ABCF1 CHD5	2.00e-03	441	41	5	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD3 CHD4 CHD5	2.25e-03	127	41	3	GO:0008094
GeneOntologyMolecularFunction	chromatin-protein adaptor activity	BAZ2A HDGFL2	3.21e-03	41	41	2	GO:0140463
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A SETBP1	3.68e-03	44	41	2	GO:0140938
GeneOntologyMolecularFunction	helicase activity	CHD3 CHD4 CHD5	4.16e-03	158	41	3	GO:0004386
GeneOntologyMolecularFunction	cadherin binding	OBSCN PKN2 RPL7A LAD1	5.04e-03	339	41	4	GO:0045296
GeneOntologyMolecularFunction	snRNA binding	SART3 LARP7	6.11e-03	57	41	2	GO:0017069
GeneOntologyMolecularFunction	nuclear receptor activity	AHR PDE3A	6.75e-03	60	41	2	GO:0004879
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	ELK1 MED12	6.97e-03	61	41	2	GO:0030374
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	AHR PDE3A	6.97e-03	61	41	2	GO:0098531
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A SETBP1	8.60e-03	68	41	2	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A SETBP1	8.85e-03	69	41	2	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A SETBP1	9.35e-03	71	41	2	GO:0042054
GeneOntologyBiologicalProcess	protein-DNA complex organization	AHR SART3 SETD1A TDRD3 KAT2B CHD3 CHD4 FBXL19 PSIP1 BAZ2A HDGFL2 CHD5 SETBP1	2.65e-08	999	40	13	GO:0071824
GeneOntologyBiologicalProcess	chromatin organization	SART3 SETD1A TDRD3 KAT2B CHD3 CHD4 FBXL19 PSIP1 BAZ2A HDGFL2 CHD5 SETBP1	7.61e-08	896	40	12	GO:0006325
GeneOntologyBiologicalProcess	chromatin remodeling	SART3 SETD1A KAT2B CHD3 CHD4 FBXL19 PSIP1 BAZ2A HDGFL2 CHD5 SETBP1	1.07e-07	741	40	11	GO:0006338
GeneOntologyBiologicalProcess	DNA-templated transcription initiation	AHR SETD1A KAT2B BAZ2A MED12	8.06e-05	231	40	5	GO:0006352
GeneOntologyCellularComponent	NuRD complex	CHD3 CHD4 CHD5	4.67e-06	17	41	3	GO:0016581
GeneOntologyCellularComponent	CHD-type complex	CHD3 CHD4 CHD5	4.67e-06	17	41	3	GO:0090545
GeneOntologyCellularComponent	nuclear protein-containing complex	AHR SART3 SETD1A MAFB TDRD3 CHD3 CHD4 INTS12 BAZ2A MED12 CHD5 LARP7	8.38e-06	1377	41	12	GO:0140513
GeneOntologyCellularComponent	chromatin	AHR SETD1A MAFB KAT2B ELK1 CHD3 CHD4 UBA1 PSIP1 BAZ2A PBXIP1 CHD5	1.74e-05	1480	41	12	GO:0000785
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	CHD3 CHD4 BAZ2A CHD5	3.71e-05	96	41	4	GO:0070603
GeneOntologyCellularComponent	heterochromatin	UBA1 PSIP1 BAZ2A CHD5	4.53e-05	101	41	4	GO:0000792
GeneOntologyCellularComponent	ATPase complex	CHD3 CHD4 BAZ2A CHD5	1.17e-04	129	41	4	GO:1904949
GeneOntologyCellularComponent	nuclear body	OBSCN SART3 SETD1A PKN2 CHD3 BAZ2A CHD5 SETBP1	3.16e-04	903	41	8	GO:0016604
GeneOntologyCellularComponent	histone deacetylase complex	CHD3 CHD4 CHD5	6.19e-04	85	41	3	GO:0000118
GeneOntologyCellularComponent	transcription regulator complex	AHR MAFB CHD3 CHD4 PBXIP1 CHD5	1.01e-03	596	41	6	GO:0005667
GeneOntologyCellularComponent	sarcomere	OBSCN KAT2B TNNT3 AHNAK2	1.41e-03	249	41	4	GO:0030017
GeneOntologyCellularComponent	myofilament	OBSCN TNNT3	1.79e-03	32	41	2	GO:0036379
GeneOntologyCellularComponent	myofibril	OBSCN KAT2B TNNT3 AHNAK2	1.97e-03	273	41	4	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	OBSCN KAT2B TNNT3 AHNAK2	2.45e-03	290	41	4	GO:0043292
GeneOntologyCellularComponent	I band	OBSCN KAT2B AHNAK2	4.20e-03	166	41	3	GO:0031674
GeneOntologyCellularComponent	A band	OBSCN KAT2B	4.68e-03	52	41	2	GO:0031672
Domain	CHDCT2	CHD3 CHD4 CHD5	7.77e-09	3	38	3	PF08074
Domain	CHDNT	CHD3 CHD4 CHD5	7.77e-09	3	38	3	PF08073
Domain	DUF1086	CHD3 CHD4 CHD5	7.77e-09	3	38	3	IPR009462
Domain	DUF1087	CHD3 CHD4 CHD5	7.77e-09	3	38	3	IPR009463
Domain	CHD_N	CHD3 CHD4 CHD5	7.77e-09	3	38	3	IPR012958
Domain	CHD_C2	CHD3 CHD4 CHD5	7.77e-09	3	38	3	IPR012957
Domain	DUF1087	CHD3 CHD4 CHD5	7.77e-09	3	38	3	PF06465
Domain	DUF1086	CHD3 CHD4 CHD5	7.77e-09	3	38	3	PF06461
Domain	DUF1087	CHD3 CHD4 CHD5	7.77e-09	3	38	3	SM01147
Domain	DUF1086	CHD3 CHD4 CHD5	7.77e-09	3	38	3	SM01146
Domain	Znf_PHD-finger	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	1.17e-08	79	38	6	IPR019787
Domain	PHD	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	2.41e-08	89	38	6	SM00249
Domain	Znf_PHD	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	2.76e-08	91	38	6	IPR001965
Domain	ZF_PHD_2	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	3.57e-08	95	38	6	PS50016
Domain	ZF_PHD_1	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	3.81e-08	96	38	6	PS01359
Domain	Zinc_finger_PHD-type_CS	CHD3 CHD4 FBXL19 INTS12 CHD5	2.00e-07	65	38	5	IPR019786
Domain	PHD	CHD3 CHD4 INTS12 BAZ2A CHD5	4.13e-07	75	38	5	PF00628
Domain	Znf_FYVE_PHD	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	4.81e-07	147	38	6	IPR011011
Domain	LEDGF	PSIP1 HDGFL2	4.03e-06	2	38	2	PF11467
Domain	LEDGF	PSIP1 HDGFL2	4.03e-06	2	38	2	IPR021567
Domain	Chromo_domain	CHD3 CHD4 CHD5	1.53e-05	24	38	3	IPR023780
Domain	Chromo	CHD3 CHD4 CHD5	1.96e-05	26	38	3	PF00385
Domain	CHROMO_1	CHD3 CHD4 CHD5	2.46e-05	28	38	3	PS00598
Domain	CHROMO_2	CHD3 CHD4 CHD5	2.46e-05	28	38	3	PS50013
Domain	-	USP5 CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	2.93e-05	449	38	7	3.30.40.10
Domain	HMGI/Y_DNA-bd_CS	PSIP1 BAZ2A SETBP1	3.36e-05	31	38	3	IPR000637
Domain	Znf_RING/FYVE/PHD	USP5 CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	3.37e-05	459	38	7	IPR013083
Domain	SNF2_N	CHD3 CHD4 CHD5	3.70e-05	32	38	3	IPR000330
Domain	Chromodomain-like	CHD3 CHD4 CHD5	3.70e-05	32	38	3	IPR016197
Domain	SNF2_N	CHD3 CHD4 CHD5	3.70e-05	32	38	3	PF00176
Domain	Chromo/shadow_dom	CHD3 CHD4 CHD5	4.06e-05	33	38	3	IPR000953
Domain	CHROMO	CHD3 CHD4 CHD5	4.06e-05	33	38	3	SM00298
Domain	DNA/RNA_helicase_DEAH_CS	CHD3 CHD4 CHD5	4.86e-05	35	38	3	IPR002464
Domain	DEAH_ATP_HELICASE	CHD3 CHD4 CHD5	6.24e-05	38	38	3	PS00690
Domain	HMG_box_dom	CHD3 CHD4 CHD5	3.11e-04	65	38	3	IPR009071
Domain	AT_hook	BAZ2A SETBP1	4.75e-04	16	38	2	PF02178
Domain	PWWP	PSIP1 HDGFL2	7.48e-04	20	38	2	SM00293
Domain	PWWP	PSIP1 HDGFL2	9.93e-04	23	38	2	PF00855
Domain	PWWP_dom	PSIP1 HDGFL2	9.93e-04	23	38	2	IPR000313
Domain	PWWP	PSIP1 HDGFL2	1.08e-03	24	38	2	PS50812
Domain	Bromodomain_CS	KAT2B BAZ2A	1.27e-03	26	38	2	IPR018359
Domain	Helicase_C	CHD3 CHD4 CHD5	1.33e-03	107	38	3	PF00271
Domain	HELICc	CHD3 CHD4 CHD5	1.33e-03	107	38	3	SM00490
Domain	Helicase_C	CHD3 CHD4 CHD5	1.37e-03	108	38	3	IPR001650
Domain	AT_hook	BAZ2A SETBP1	1.37e-03	27	38	2	SM00384
Domain	AT_hook_DNA-bd_motif	BAZ2A SETBP1	1.37e-03	27	38	2	IPR017956
Domain	HELICASE_CTER	CHD3 CHD4 CHD5	1.41e-03	109	38	3	PS51194
Domain	HELICASE_ATP_BIND_1	CHD3 CHD4 CHD5	1.41e-03	109	38	3	PS51192
Domain	DEXDc	CHD3 CHD4 CHD5	1.41e-03	109	38	3	SM00487
Domain	Helicase_ATP-bd	CHD3 CHD4 CHD5	1.44e-03	110	38	3	IPR014001
Domain	UBA	USP5 TDRD3	1.69e-03	30	38	2	SM00165
Domain	UBA	USP5 TDRD3	2.43e-03	36	38	2	PF00627
Domain	BROMODOMAIN_1	KAT2B BAZ2A	2.57e-03	37	38	2	PS00633
Domain	Bromodomain	KAT2B BAZ2A	2.71e-03	38	38	2	PF00439
Domain	BROMODOMAIN_2	KAT2B BAZ2A	3.14e-03	41	38	2	PS50014
Domain	BROMO	KAT2B BAZ2A	3.30e-03	42	38	2	SM00297
Domain	Bromodomain	KAT2B BAZ2A	3.30e-03	42	38	2	IPR001487
Domain	-	KAT2B BAZ2A	3.30e-03	42	38	2	1.20.920.10
Domain	UBA	USP5 TDRD3	3.61e-03	44	38	2	IPR015940
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	SETD1A KAT2B CHD3 CHD4 PSIP1 BAZ2A	1.08e-05	254	29	6	M27131
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	SETD1A KAT2B PSIP1	6.29e-05	38	29	3	MM17073
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	SETD1A KAT2B PSIP1	8.51e-05	42	29	3	M48018
Pathway	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION	KAT2B CHD3 CHD4	1.19e-04	47	29	3	M1095
Pathway	PID_HDAC_CLASSI_PATHWAY	KAT2B CHD3 CHD4	3.28e-04	66	29	3	M101
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SART3 TDRD3 PKN2 CHD3 CHD4 UBA1 ABCF1 PTPN13 PSIP1 BAZ2A HDGFL2 RPL7A AHNAK2	4.32e-11	934	42	13	33916271
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART3 ZSWIM8 USP5 CHD4 ABCF1 BAZ2A CCDC86 MED12 RPL7A LARP7 RRP1	2.37e-10	653	42	11	22586326
Pubmed	Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.	CHD3 CHD4 ABCF1 CCDC86 HDGFL2	7.33e-09	56	42	5	26919559
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SART3 TDRD3 ABCF1 PTPN13 INTS12 BAZ2A CCDC86 HDGFL2 PBXIP1 MED12 LARP7 RRP1 C6orf132	1.31e-08	1497	42	13	31527615
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	TDRD3 CHD3 CHD4 ABCF1 PSIP1 CCDC86 MED12 RPL7A LARP7 RRP1	1.81e-08	759	42	10	35915203
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	SART3 ABCF1 BAZ2A CCDC86 HDGFL2 RPL7A LARP7	2.04e-08	251	42	7	28077445
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	CHD3 CHD4 ABCF1 PSIP1 HDGFL2 RPL7A CHD5 LARP7 RRP1	3.68e-08	605	42	9	28977666
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CHD3 CHD4 INTS12 PSIP1 BAZ2A CCDC86 HDGFL2 CHD5 RRP1	3.83e-08	608	42	9	36089195
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SART3 SETD1A USP5 PKN2 CHD4 UBA1 ABCF1 BAZ2A CCDC86 MED12 RPL7A AHNAK2	4.29e-08	1353	42	12	29467282
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	USP5 PKN2 CHD3 CHD4 UBA1 ABCF1 AHNAK2	1.37e-07	332	42	7	32786267
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SART3 TDRD3 UBA1 ABCF1 PSIP1 CCDC86 RPL7A LARP7 RRP1	4.19e-07	807	42	9	22681889
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	CHD3 CHD4 ABCF1 PSIP1 CCDC86 RPL7A RRP1	6.36e-07	417	42	7	36537216
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SART3 USP5 PKN2 CHD4 UBA1 ABCF1 PSIP1 CCDC86 HDGFL2 RPL7A AHNAK2	6.51e-07	1415	42	11	28515276
Pubmed	DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.	CHD3 CHD4 CHD5	7.38e-07	15	42	3	35695185
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SART3 PKN2 ABCF1 PTPN13 PSIP1 BAZ2A HDGFL2 PBXIP1 RPL7A LARP7 RRP1	1.06e-06	1487	42	11	33957083
Pubmed	A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.	CHD3 CHD4 CHD5	1.10e-06	17	42	3	27806305
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	SART3 CHD3 CHD4 UBA1 INTS12	1.27e-06	156	42	5	37108203
Pubmed	Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.	PSIP1 HDGFL2	1.42e-06	2	42	2	16337983
Pubmed	Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.	CHD3 CHD4	1.42e-06	2	42	2	7560064
Pubmed	CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5.	CHD4 BAZ2A	1.42e-06	2	42	2	23796711
Pubmed	LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.	PSIP1 HDGFL2	1.42e-06	2	42	2	31616795
Pubmed	Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering.	PSIP1 HDGFL2	1.42e-06	2	42	2	15797927
Pubmed	The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif.	PKN2 PTPN13	1.42e-06	2	42	2	11356191
Pubmed	HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.	PSIP1 HDGFL2	1.42e-06	2	42	2	23046603
Pubmed	Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development.	CHD3 CHD4	1.42e-06	2	42	2	35568926
Pubmed	The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.	CHD3 CHD4	1.42e-06	2	42	2	7575689
Pubmed	Two forms of the major antigenic protein of the dermatomyositis-specific Mi-2 autoantigen.	CHD3 CHD4	1.42e-06	2	42	2	8843877
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	SART3 SETD1A ZSWIM8 USP5 PTPN13 PBXIP1	2.02e-06	313	42	6	38270169
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SART3 USP5 CHD3 CHD4 UBA1 PSIP1 HDGFL2 MED12 LARP7	2.76e-06	1014	42	9	32416067
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CHD3 CHD4 UBA1 ABCF1 PSIP1 GAS2L3 CCDC86 RPL7A RRP1	2.99e-06	1024	42	9	24711643
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PKN2 CHD3 CHD4 UBA1 ABCF1 PSIP1 BAZ2A CCDC86	3.51e-06	774	42	8	15302935
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	CHD4 ABCF1 BAZ2A CCDC86 LARP7 RRP1	3.78e-06	349	42	6	25665578
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	AHR SART3 CHD3 CHD4 PSIP1 GAS2L3 CCDC86 LARP7 RRP1 LAD1	4.07e-06	1371	42	10	36244648
Pubmed	The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.	CHD3 CHD4	4.27e-06	3	42	2	32658897
Pubmed	Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.	PSIP1 HDGFL2	4.27e-06	3	42	2	33477970
Pubmed	Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.	PSIP1 HDGFL2	4.27e-06	3	42	2	15371438
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CHD4 ABCF1 PTPN13 PSIP1 CCDC86 PBXIP1 MED12 RPL7A RRP1	4.67e-06	1082	42	9	38697112
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	OBSCN SETD1A TDRD3 FBXL19 MED12 CHD5 C6orf132 LAD1 AHNAK2	5.54e-06	1105	42	9	35748872
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	SART3 PKN2 UBA1 ABCF1 CCDC86	6.08e-06	215	42	5	35973513
Pubmed	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.	SART3 MAFB CCDC86 LARP7 RRP1	6.80e-06	220	42	5	31822558
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	CHD3 CHD4 BAZ2A CHD5	7.45e-06	103	42	4	32744500
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SART3 SETD1A CHD3 UBA1 CCDC86 RRP1	7.56e-06	394	42	6	27248496
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	AHR USP5 PKN2 CHD4 UBA1 PTPN13	8.24e-06	400	42	6	35013556
Pubmed	Characterization of the CHD family of proteins.	CHD3 CHD4	8.53e-06	4	42	2	9326634
Pubmed	Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.	USP5 MAFB	8.53e-06	4	42	2	28933784
Pubmed	NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.	CHD3 CHD4	8.53e-06	4	42	2	16574654
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	AHR MAFB KAT2B ELK1 CHD4 FBXL19 ZNF688 PBXIP1	8.74e-06	877	42	8	20211142
Pubmed	Identification of the BRD1 interaction network and its impact on mental disorder risk.	CHD3 CHD4 CHD5	1.04e-05	35	42	3	27142060
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	SART3 CHD3 ABCF1 CCDC86 RPL7A RRP1	1.16e-05	425	42	6	21081503
Pubmed	Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.	CHD3 CHD4 CHD5	1.34e-05	38	42	3	33283408
Pubmed	A ubiquitin shuttle DC-UbP/UBTD2 reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 enzymes.	USP5 UBA1	1.42e-05	5	42	2	25207809
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CHD3 CHD4 INTS12 PSIP1 BAZ2A CCDC86 HDGFL2 RPL7A RRP1	1.95e-05	1294	42	9	30804502
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	SART3 UBA1 ABCF1 RPL7A LARP7 RRP1	2.03e-05	469	42	6	37314180
Pubmed	Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.	PSIP1 CCDC86 LARP7 RRP1	2.10e-05	134	42	4	28695742
Pubmed	Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation.	PSIP1 SETBP1	2.13e-05	6	42	2	35036869
Pubmed	Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.	CHD3 CHD4	2.13e-05	6	42	2	17626165
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SART3 CHD3 PSIP1 BAZ2A HDGFL2	2.29e-05	283	42	5	30585729
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	CHD4 ABCF1 CCDC86 RPL7A LARP7 RRP1	2.39e-05	483	42	6	36912080
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	SART3 ZSWIM8 CHD3 CHD4 UBA1 ABCF1 CCDC86 RPL7A RRP1	2.50e-05	1335	42	9	29229926
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	SART3 CHD3 UBA1 PSIP1 GAS2L3 LARP7 RRP1	2.53e-05	732	42	7	34732716
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	USP5 IQCA1L ABCF1 CCDC86 FER1L4 LARP7	2.77e-05	496	42	6	31343991
Pubmed	Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.	CHD4 HDGFL2 RPL7A RRP1	2.87e-05	145	42	4	27049334
Pubmed	The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock.	UBA1 ABCF1	2.98e-05	7	42	2	30770245
Pubmed	Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.	PSIP1 HDGFL2	2.98e-05	7	42	2	26721387
Pubmed	Mammalian chromodomain proteins: their role in genome organisation and expression.	CHD3 CHD4	3.97e-05	8	42	2	10655032
Pubmed	Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.	SART3 LARP7	3.97e-05	8	42	2	24316072
Pubmed	BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.	CHD3 CHD5 AHNAK2	4.11e-05	55	42	3	33067418
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	CHD3 CHD4 ABCF1 PTPN13 PSIP1 CCDC86	4.14e-05	533	42	6	30554943
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SART3 CHD4 UBA1 ABCF1 PSIP1 CCDC86 RPL7A LARP7 RRP1	4.16e-05	1425	42	9	30948266
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	CHD4 PSIP1 HDGFL2 LARP7	4.53e-05	163	42	4	22113938
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SART3 CHD3 CHD4 INTS12 PSIP1 HDGFL2 RPL7A CHD5 LARP7	4.56e-05	1442	42	9	35575683
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	AHR KAT2B ELK1 CHD3 FBXL19 INTS12 BAZ2A	4.73e-05	808	42	7	20412781
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	CHD3 CHD4 BAZ2A CCDC86 CHD5	4.76e-05	330	42	5	33301849
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A PKN2 UBA1 PTPN13 BAZ2A MED12	4.87e-05	549	42	6	38280479
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	SART3 USP5 PDE3A UBA1 ABCF1 HDGFL2 RPL7A LARP7 AHNAK2	4.89e-05	1455	42	9	22863883
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SART3 BAZ2A CCDC86 LARP7 RRP1	4.90e-05	332	42	5	25693804
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	AHR ZSWIM8 KAT2B CHD3 CHD4 BAZ2A CHD5 LARP7	4.90e-05	1116	42	8	31753913
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	OBSCN UBA1 PSIP1 CCDC86 HDGFL2	5.04e-05	334	42	5	30425250
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SART3 SETD1A CHD3 BAZ2A MED12	5.56e-05	341	42	5	32971831
Pubmed	Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.	SART3 USP5 UBA1	5.89e-05	62	42	3	26508657
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	SART3 CHD3 CHD4 UBA1 RPL7A CHD5 LARP7 RRP1	6.17e-05	1153	42	8	29845934
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	CHD3 CHD4 PSIP1 CCDC86 RPL7A LARP7 RRP1	6.36e-05	847	42	7	35850772
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SART3 USP5 CHD3 CHD4 PSIP1 HDGFL2 RPL7A	6.36e-05	847	42	7	35235311
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	CHD3 CHD4 UBA1 RPL7A	7.10e-05	183	42	4	36129980
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	USP5 UBA1 PBXIP1 LAD1 AHNAK2	7.18e-05	360	42	5	33111431
Pubmed	Targeting HIV transcription: the quest for a functional cure.	KAT2B LARP7	7.78e-05	11	42	2	25731772
Pubmed	Human USP3 is a chromatin modifier required for S phase progression and genome stability.	USP5 UBA1	7.78e-05	11	42	2	17980597
Pubmed	Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.	CHD3 CHD4	7.78e-05	11	42	2	10204490
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	CHD4 ABCF1 CCDC86 HDGFL2 RPL7A RRP1	8.03e-05	601	42	6	33658012
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	SETD1A CHD4 MED12	8.12e-05	69	42	3	28481362
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	ABCF1 PSIP1 PBXIP1 RPL7A RRP1	8.70e-05	375	42	5	32788342
Pubmed	NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.	CHD3 CHD4	9.32e-05	12	42	2	22560079
Pubmed	CHD4 and the NuRD complex directly control cardiac sarcomere formation.	CHD4 TNNT3	9.32e-05	12	42	2	29891665
Pubmed	NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.	CHD3 CHD4	9.32e-05	12	42	2	9885572
Pubmed	Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.	MAFB CHD3 ABCF1 RPL7A RRP1	9.72e-05	384	42	5	31059266
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	KAT2B CHD4 BAZ2A	1.04e-04	75	42	3	25593309
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	AHR CHD4 ABCF1 MED12 RPL7A LARP7 RRP1 LAD1	1.06e-04	1247	42	8	27684187
Pubmed	LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.	CHD3 CHD4	1.10e-04	13	42	2	19703393
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	SART3 USP5 PKN2 CHD4 UBA1 RPL7A	1.11e-04	638	42	6	33239621
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SART3 UBA1 ABCF1 PSIP1 RPL7A CHD5 RRP1 LAD1	1.12e-04	1257	42	8	36526897
Interaction	SIRT7 interactions	SART3 ZSWIM8 USP5 KAT2B CHD4 ABCF1 BAZ2A CCDC86 MED12 RPL7A LARP7 RRP1	2.34e-08	744	42	12	int:SIRT7
Interaction	NAA40 interactions	SART3 TDRD3 PKN2 CHD3 CHD4 UBA1 ABCF1 PTPN13 PSIP1 BAZ2A HDGFL2 RPL7A AHNAK2	5.25e-08	978	42	13	int:NAA40
Interaction	H2BC9 interactions	TDRD3 CHD3 CHD4 ABCF1 PSIP1 HDGFL2 RPL7A LARP7 SETBP1	2.74e-07	446	42	9	int:H2BC9
Interaction	PYHIN1 interactions	SART3 CHD4 ABCF1 BAZ2A CCDC86 HDGFL2 RPL7A LARP7	6.39e-07	358	42	8	int:PYHIN1
Interaction	MAFB interactions	SART3 USP5 MAFB KAT2B CCDC86 LARP7 RRP1	6.95e-07	246	42	7	int:MAFB
Interaction	EFTUD2 interactions	SART3 USP5 PKN2 CHD3 CHD4 UBA1 ABCF1 PSIP1 CCDC86 HDGFL2 MED12 RPL7A LARP7 AHNAK2	7.22e-07	1449	42	14	int:EFTUD2
Interaction	IFI16 interactions	OBSCN SART3 CHD4 UBA1 ABCF1 BAZ2A CCDC86 RPL7A LARP7 RRP1	1.54e-06	714	42	10	int:IFI16
Interaction	H3-3A interactions	SETD1A KAT2B CHD3 CHD4 INTS12 PSIP1 BAZ2A HDGFL2 CHD5 RRP1	2.37e-06	749	42	10	int:H3-3A
Interaction	CHD4 interactions	SETD1A CHD3 CHD4 ABCF1 PSIP1 BAZ2A HDGFL2 RPL7A CHD5 LARP7 RRP1	2.38e-06	938	42	11	int:CHD4
Interaction	CMSS1 interactions	AHR SART3 MAFB PBXIP1 LARP7	5.76e-06	124	42	5	int:CMSS1
Interaction	MEN1 interactions	SART3 SETD1A CHD3 CHD4 PSIP1 BAZ2A CCDC86 MED12 RPL7A RRP1 SETBP1	5.79e-06	1029	42	11	int:MEN1
Interaction	MAF interactions	AHR USP5 MAFB UBA1	7.30e-06	60	42	4	int:MAF
Interaction	DAXX interactions	SETD1A CHD4 ABCF1 CCDC86 HDGFL2 PBXIP1 LARP7	7.59e-06	353	42	7	int:DAXX
Interaction	H2AC4 interactions	SART3 SETD1A KAT2B CHD3 CHD4 CCDC86 LARP7 RRP1	8.32e-06	506	42	8	int:H2AC4
Interaction	RPL18 interactions	SART3 MAFB CHD3 CHD4 RPL7A LARP7 RRP1 AHNAK2	9.07e-06	512	42	8	int:RPL18
Interaction	PARP1 interactions	AHR SETD1A USP5 KAT2B PKN2 CHD3 CHD4 UBA1 PTPN13 PSIP1 HDGFL2 LARP7	1.01e-05	1316	42	12	int:PARP1
Interaction	H2AC11 interactions	SART3 PKN2 CHD4 RPL7A LARP7 AHNAK2	1.18e-05	248	42	6	int:H2AC11
Interaction	XRCC6 interactions	SART3 KAT2B CHD3 CHD4 UBA1 INTS12 PSIP1 BAZ2A HDGFL2 LARP7	1.57e-05	928	42	10	int:XRCC6
Interaction	HABP4 interactions	CHD3 PSIP1 CCDC86 LARP7 RRP1	1.76e-05	156	42	5	int:HABP4
Interaction	HTATSF1 interactions	CHD3 CHD4 HDGFL2 PBXIP1 LARP7	1.81e-05	157	42	5	int:HTATSF1
Interaction	EP300 interactions	AHR SART3 SETD1A USP5 KAT2B PKN2 ELK1 CHD3 CHD4 ABCF1 PSIP1 LARP7	1.90e-05	1401	42	12	int:EP300
Interaction	CSNK2A1 interactions	SART3 SETD1A MAFB KAT2B CHD3 CHD4 INTS12 PSIP1 HDGFL2 LARP7	2.02e-05	956	42	10	int:CSNK2A1
Interaction	FTSJ3 interactions	SART3 CHD3 CHD4 PSIP1 RPL7A LARP7 RRP1	2.41e-05	422	42	7	int:FTSJ3
Interaction	HECTD1 interactions	TDRD3 CHD3 CHD4 ABCF1 PSIP1 CCDC86 MED12 RPL7A LARP7 RRP1	2.60e-05	984	42	10	int:HECTD1
Interaction	H2AX interactions	KAT2B CHD4 PSIP1 BAZ2A CCDC86 HDGFL2 RPL7A LARP7	2.62e-05	593	42	8	int:H2AX
Interaction	NIFK interactions	MAFB CHD3 CHD4 CCDC86 RPL7A LARP7 RRP1	2.75e-05	431	42	7	int:NIFK
Interaction	BRIX1 interactions	SART3 MAFB CHD3 CHD4 RPL7A LARP7	3.46e-05	300	42	6	int:BRIX1
Interaction	ZBTB2 interactions	PKN2 CHD3 CHD4 BAZ2A CCDC86 CHD5 LARP7	3.63e-05	450	42	7	int:ZBTB2
Interaction	NUP43 interactions	SETD1A CHD3 PSIP1 BAZ2A MED12 RPL7A LARP7 AHNAK2	3.80e-05	625	42	8	int:NUP43
Interaction	SIRT6 interactions	AHR SART3 SETD1A CHD3 CHD4 ABCF1 MED12 LARP7	3.93e-05	628	42	8	int:SIRT6
Interaction	RAD18 interactions	SART3 SETD1A USP5 MAFB CHD4 HDGFL2 RRP1	4.00e-05	457	42	7	int:RAD18
Interaction	NOP58 interactions	MAFB CHD3 CHD4 MED12 LARP7 RRP1	4.08e-05	309	42	6	int:NOP58
Interaction	RRP1B interactions	SART3 MAFB CHD3 CHD4 RPL7A LARP7	4.46e-05	314	42	6	int:RRP1B
Interaction	CBX3 interactions	SETD1A MAFB CHD3 CHD4 PSIP1 BAZ2A HDGFL2 CHD5	4.80e-05	646	42	8	int:CBX3
Interaction	RNF2 interactions	SART3 CHD3 CHD4 ABCF1 PBXIP1 RPL7A LARP7 RRP1 LAD1	5.95e-05	866	42	9	int:RNF2
Interaction	PSIP1 interactions	CHD3 CHD4 PSIP1 HDGFL2 SETBP1	6.50e-05	205	42	5	int:PSIP1
Interaction	H3C3 interactions	CHD3 CHD4 INTS12 BAZ2A CCDC86 HDGFL2 CHD5	6.62e-05	495	42	7	int:H3C3
Interaction	WDR5 interactions	SART3 SETD1A KAT2B CHD3 CHD4 ABCF1 PSIP1 HDGFL2 RPL7A SETBP1	6.74e-05	1101	42	10	int:WDR5
Interaction	KAT6A interactions	CHD3 CHD4 ABCF1 PSIP1 CCDC86 RPL7A RRP1	7.98e-05	510	42	7	int:KAT6A
Interaction	H3C1 interactions	SETD1A KAT2B CHD3 CHD4 PSIP1 BAZ2A HDGFL2 RPL7A LARP7	8.07e-05	901	42	9	int:H3C1
Interaction	OBSL1 interactions	IQCA1L CHD4 UBA1 ABCF1 PSIP1 CCDC86 RPL7A LARP7 RRP1	8.14e-05	902	42	9	int:OBSL1
Interaction	MYCN interactions	SART3 USP5 KAT2B CHD4 ABCF1 PSIP1 CCDC86 HDGFL2 RPL7A LARP7 RRP1	8.44e-05	1373	42	11	int:MYCN
Interaction	MBD3L2 interactions	CHD3 CHD4 CHD5	8.49e-05	41	42	3	int:MBD3L2
Interaction	C7orf50 interactions	MAFB CHD3 CHD4 RPL7A LARP7	8.69e-05	218	42	5	int:C7orf50
Interaction	DHX30 interactions	SART3 MAFB TDRD3 CHD3 CHD4 RPL7A LARP7	8.70e-05	517	42	7	int:DHX30
Interaction	KPNA2 interactions	SART3 SETD1A MAFB CHD3 CHD4 UBA1 LARP7	8.91e-05	519	42	7	int:KPNA2
Interaction	GATAD2A interactions	KAT2B CHD3 CHD4 INTS12 CHD5	9.87e-05	224	42	5	int:GATAD2A
Interaction	KRI1 interactions	MAFB CHD3 CHD4 RPL7A LARP7	1.01e-04	225	42	5	int:KRI1
Interaction	RPL15 interactions	ZSWIM8 MAFB CHD3 CHD4 CCDC86 RPL7A LARP7	1.02e-04	530	42	7	int:RPL15
Interaction	RPS27A interactions	USP5 CHD3 CHD4 UBA1 MED12 RPL7A LARP7	1.09e-04	536	42	7	int:RPS27A
Interaction	SNAI2 interactions	USP5 KAT2B CHD4	1.20e-04	46	42	3	int:SNAI2
Interaction	SERBP1 interactions	USP5 TDRD3 KAT2B CHD3 CHD4 UBA1 PSIP1 CCDC86 RPL7A LARP7 RRP1	1.23e-04	1432	42	11	int:SERBP1
Interaction	KRR1 interactions	MAFB CHD3 CHD4 CCDC86 RPL7A LARP7	1.26e-04	379	42	6	int:KRR1
Interaction	POLDIP3 interactions	CHD3 CHD4 PSIP1 MED12 LARP7	1.29e-04	237	42	5	int:POLDIP3
Interaction	NPM1 interactions	SART3 TDRD3 CHD3 CHD4 PSIP1 CCDC86 RPL7A LARP7 RRP1 AHNAK2	1.39e-04	1201	42	10	int:NPM1
Interaction	ZBTB5 interactions	KAT2B CHD3 CHD4	1.45e-04	49	42	3	int:ZBTB5
Interaction	CDK2AP2 interactions	CHD3 CHD4 CHD5	1.45e-04	49	42	3	int:CDK2AP2
Interaction	GRWD1 interactions	SETD1A MAFB CHD4 UBA1 RPL7A LARP7	1.47e-04	390	42	6	int:GRWD1
Interaction	NKRF interactions	MAFB CHD3 CHD4 RPL7A LARP7	1.47e-04	244	42	5	int:NKRF
Interaction	EEF1E1 interactions	PKN2 UBA1 RPL7A LARP7	1.49e-04	129	42	4	int:EEF1E1
Interaction	GATAD2B interactions	KAT2B CHD3 CHD4 CHD5 LARP7	1.50e-04	245	42	5	int:GATAD2B
Interaction	RPL4 interactions	SART3 IQCA1L MAFB CHD3 CHD4 HDGFL2 RPL7A LARP7	1.55e-04	764	42	8	int:RPL4
Interaction	NOP56 interactions	MAFB CHD3 CHD4 ABCF1 CCDC86 RPL7A LARP7	1.59e-04	570	42	7	int:NOP56
Interaction	RPL17 interactions	SART3 MAFB CHD3 CHD4 CCDC86 RPL7A LARP7	1.61e-04	571	42	7	int:RPL17
Interaction	ZCRB1 interactions	MAFB CCDC86 RPL7A LARP7	1.72e-04	134	42	4	int:ZCRB1
Interaction	RBPJ interactions	SART3 KAT2B CHD3 CHD4 PSIP1	1.78e-04	254	42	5	int:RBPJ
Interaction	H2BC3 interactions	SETD1A KAT2B CHD3 CHD4 CCDC86 LARP7	1.83e-04	406	42	6	int:H2BC3
Interaction	DDX50 interactions	MAFB CHD3 CHD4 RPL7A LARP7	1.88e-04	257	42	5	int:DDX50
Interaction	PES1 interactions	SETD1A MAFB CHD4 RPL7A LARP7	1.91e-04	258	42	5	int:PES1
Interaction	ARRDC2 interactions	SART3 SETD1A ZSWIM8	1.94e-04	54	42	3	int:ARRDC2
Interaction	SLC25A6 interactions	MAFB ELK1 CHD3 CHD4 RPL7A LARP7	1.95e-04	411	42	6	int:SLC25A6
Interaction	VARS1 interactions	SART3 PKN2 CHD4 HDGFL2 LARP7	1.98e-04	260	42	5	int:VARS1
Interaction	SUMO2 interactions	USP5 PKN2 CHD3 CHD4 UBA1 ABCF1 AHNAK2	1.99e-04	591	42	7	int:SUMO2
Interaction	REXO4 interactions	CHD3 CHD4 CCDC86 RPL7A LARP7	2.02e-04	261	42	5	int:REXO4
Interaction	RAD51B interactions	CHD3 CHD4 CHD5	2.05e-04	55	42	3	int:RAD51B
Interaction	EEF1A1P5 interactions	USP5 HDGFL2 CHD5 LARP7	2.09e-04	141	42	4	int:EEF1A1P5
Interaction	USP36 interactions	CHD3 CHD4 ABCF1 CCDC86 RPL7A LARP7 RRP1	2.16e-04	599	42	7	int:USP36
Interaction	PPAN-P2RY11 interactions	SART3 CHD4 RPL7A LARP7	2.27e-04	144	42	4	int:PPAN-P2RY11
Interaction	RPS15 interactions	SART3 CHD3 CHD4 PSIP1 RPL7A LARP7	2.28e-04	423	42	6	int:RPS15
Interaction	PRPF4 interactions	SART3 MAFB CHD3 CHD4 LARP7	2.40e-04	271	42	5	int:PRPF4
Interaction	BRD2 interactions	CHD3 CHD4 PSIP1 BAZ2A HDGFL2 LARP7	2.46e-04	429	42	6	int:BRD2
Interaction	BAG2 interactions	SETD1A TDRD3 ELK1 CHD4 MED12 CHD5 LARP7	2.72e-04	622	42	7	int:BAG2
Interaction	RPL22 interactions	CHD3 CHD4 FBXL19 HDGFL2 RPL7A LARP7	2.82e-04	440	42	6	int:RPL22
Interaction	G3BP1 interactions	USP5 TDRD3 CHD3 CHD4 UBA1 INTS12 RPL7A LARP7	2.83e-04	835	42	8	int:G3BP1
Interaction	THRAP3 interactions	SART3 CHD3 CHD4 PSIP1 MED12 LARP7	2.93e-04	443	42	6	int:THRAP3
Interaction	GTPBP4 interactions	SART3 MAFB CHD3 CHD4 RPL7A LARP7	2.93e-04	443	42	6	int:GTPBP4
Interaction	SNU13 interactions	SART3 MAFB CHD3 CHD4 LARP7	3.03e-04	285	42	5	int:SNU13
Interaction	OLA1 interactions	SART3 MAFB RPL7A LAD1	3.08e-04	156	42	4	int:OLA1
Interaction	H3C14 interactions	SETD1A KAT2B CHD4 HDGFL2	3.08e-04	156	42	4	int:H3C14
Interaction	H3-4 interactions	TDRD3 KAT2B CHD4 ABCF1 TNNT3 CHD5	3.11e-04	448	42	6	int:H3-4
Interaction	MRE11 interactions	KAT2B CHD3 CHD4 ABCF1 LARP7	3.13e-04	287	42	5	int:MRE11
Interaction	RPL6 interactions	SART3 CHD3 CHD4 ABCF1 PSIP1 RPL7A LARP7	3.14e-04	637	42	7	int:RPL6
Interaction	RRP15 interactions	SART3 MAFB RPL7A LARP7	3.15e-04	157	42	4	int:RRP15
Interaction	CAPRIN1 interactions	TDRD3 CHD3 CHD4 MED12 RPL7A LARP7	3.22e-04	451	42	6	int:CAPRIN1
Interaction	HDLBP interactions	SART3 TDRD3 CHD3 CHD4 PSIP1 GAS2L3 CCDC86 LARP7	3.32e-04	855	42	8	int:HDLBP
Interaction	PRPF3 interactions	SART3 MAFB CHD3 CHD4 LARP7	3.33e-04	291	42	5	int:PRPF3
Interaction	RPL27A interactions	CHD3 CHD4 ABCF1 CCDC86 RPL7A LARP7	3.54e-04	459	42	6	int:RPL27A
Interaction	NOL10 interactions	CHD3 CHD4 RPL7A LARP7	3.55e-04	162	42	4	int:NOL10
Interaction	RPS3A interactions	SART3 CHD3 CHD4 CCDC86 MED12 RPL7A LARP7	3.72e-04	655	42	7	int:RPS3A
Interaction	TAOK2 interactions	DLGAP3 ELK1 PDE3A PBXIP1	3.72e-04	164	42	4	int:TAOK2
Cytoband	16p11.2	SETD1A FBXL19 ZNF688	7.22e-04	191	42	3	16p11.2
Cytoband	12p13	USP5 CHD4	1.59e-03	64	42	2	12p13
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	SETD1A FBXL19 ZNF688	2.12e-03	278	42	3	chr16p11
GeneFamily	PHD finger proteins	CHD3 CHD4 FBXL19 INTS12 BAZ2A CHD5	5.57e-09	90	29	6	88
GeneFamily	PHD finger proteins\|NuRD complex	CHD3 CHD4 CHD5	8.08e-07	12	29	3	1305
GeneFamily	RNA binding motif containing	SART3 SETD1A LARP7	4.70e-03	213	29	3	725
Drug	Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; HL60; HG-U133A	ZSWIM8 TDRD3 BAZ2A ZNF688 PBXIP1 MED12 LAD1	5.92e-08	198	41	7	1431_UP
Disease	bilirubin measurement	AHR MAFB PKN2 PDE3A CHD3 HDGFL2	2.72e-05	442	40	6	EFO_0004570
Disease	Graves disease	SETD1A ABCF1 FBXL19	1.83e-04	81	40	3	EFO_0004237
Disease	Developmental Disabilities	SETD1A CHD4	7.61e-04	30	40	2	C0008073
Disease	Ischemic stroke	KAT2B PDE3A CHD3 SETBP1	9.55e-04	324	40	4	HP_0002140
Disease	lung adenocarcinoma (is_implicated_in)	CHD4 PTPN13	2.02e-03	49	40	2	DOID:3910 (is_implicated_in)
Disease	creatinine measurement	OBSCN AHR MAFB DLGAP3 KAT2B SETBP1	2.09e-03	995	40	6	EFO_0004518
Disease	Pneumonia	AHR ABCF1	2.45e-03	54	40	2	C0032285
Disease	response to TNF antagonist	MAFB PDE3A	2.45e-03	54	40	2	EFO_0004653
Disease	Experimental Lung Inflammation	AHR ABCF1	2.45e-03	54	40	2	C0887898
Disease	Pneumonitis	AHR ABCF1	2.45e-03	54	40	2	C3714636
Disease	Lobar Pneumonia	AHR ABCF1	2.45e-03	54	40	2	C0032300
Disease	Intellectual Disability	SETD1A CHD3 LARP7 SETBP1	3.09e-03	447	40	4	C3714756
Disease	total blood protein measurement	ZSWIM8 MAFB KAT2B FBXL19	3.14e-03	449	40	4	EFO_0004536

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKPVQKTVKPIPAEG	AHR	16	P35869
EEDEVPAPKPRGGKK	ABCF1	111	Q8NE71
GRALPPEVKVEGPKE	ELK1	241	P19419
ELPVIPKGKPKSGRV	CCDC86	231	Q9H6F5
PVPIRKAKTKEGKGP	CHD5	236	Q8TDI0
VPKVKRGRGRPPKVK	BAZ2A	666	Q9UIF9
NEPPTPRKKVKGGRE	FBXL19	221	Q6PCT2
GVDIPKKPRLEKPET	INTS12	111	Q96CB8
PEERKKGVPEKSPVL	LAD1	166	O00515
VKKEPLGRAERPGRP	MAFB	31	Q9Y5Q3
RGKPVVEGSLEKKPP	KAT2B	201	Q92831
KRPVGKGRKQPEPLE	FER1L4	1716	A9Z1Z3
KGKPRGEEIPTQKPD	PDE3A	1126	Q14432
EEAPRKPGIFPKTVK	LARP7	191	Q4G0J3
KPPPKEKIEGTLGVL	MED12	711	Q93074
SDVSVKKPPRGRKPA	HDGFL2	266	Q7Z4V5
GRPEGLEKEGPPRKK	OBSCN	7431	Q5VST9
GPPRKRKRASEPGDK	RBBP8NL	611	Q8NC74
VAPQSKEGKKGPRLP	C6orf132	496	Q5T0Z8
PRREKGPVKEVPGTK	CSAG1	61	Q6PB30
QPPPIRRAKTKEGKG	CHD3	251	Q12873
KSKEKQGRPPGALVP	GAS2L3	341	Q86XJ1
IPKKPLRGRGVPVKE	DLGAP3	916	O95886
GPPVELRQRKKPKSS	DPY19L4	6	Q7Z388
PPVEVPIRKAKTKEG	CHD4	251	Q14839
RKVPEKPETRKAPGG	SART3	881	Q15020
GPEKKPIPGIDVLSK	PTPN13	281	Q12923
PKRRSGPIKPEKILE	TDRD3	531	Q9H7E2
KAAGKGDVPTKRPPV	RPL7A	121	P62424
KEEERPLRAPKKTPG	IQCA1L	456	A6NCM1
REKPSAGPPTKEVRK	PPP1R32	116	Q7Z5V6
KGEKEPPSPGMERKR	RRP1	376	P56182
DKKVKPPFIPTIRGR	PKN2	926	Q16513
RPGTKPPKRDEERGK	SETD1A	936	O15047
PKLDLKGPKAEVRVP	AHNAK2	3581	Q8IVF2
GRPAATEVKIPKPRG	PSIP1	181	O75475
KEGKRQGPKEPPRKS	PBXIP1	531	Q96AQ6
LSKKRRVSGPDPKPG	UBA1	6	P22314
EVPRAKGPRKAPVKE	ZNF688	116	P0C7X2
KGPRKAPVKESPEVL	ZNF688	121	P0C7X2
TEPAVRPKEPGTKRK	ZSWIM8	536	A7E2V4
RPKLTAPKIPEGEKV	TNNT3	51	P45378
AEKVIPGGVSKPRKP	SETBP1	486	Q9Y6X0
PPRKKPTRLAIGVEG	USP5	91	P45974