Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32 VPS54 DST

1.50e-06991688GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32 VPS54 DST

1.61e-061001688GO:0045103
GeneOntologyBiologicalProcessintermediate filament organization

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

3.38e-05751686GO:0045109
DomainARM-type_fold

PDS5B WAPL COPB1 USP9X CIP2A LRRK2 RICTOR USP9Y INF2 INTS4 RIC8A NUP188 HEATR3 XPO7

2.27e-0633916714IPR016024
DomainKeratin_I

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

2.49e-06441676IPR002957
DomainPrefoldin

KRT10 KRT15 KRT17 KIF21A FYCO1 TXLNA TLE1

3.64e-06721677IPR009053
DomainIntermediate_filament_CS

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

2.08e-05631676IPR018039
DomainARM-like

PDS5B COPB1 USP9X CIP2A LRRK2 RICTOR USP9Y INTS4 RIC8A HEATR3 XPO7

3.24e-0527016711IPR011989
DomainFilament

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

4.14e-05711676SM01391
DomainIF

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

4.48e-05721676PS00226
DomainFilament

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

4.85e-05731676PF00038
DomainIF

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

6.09e-05761676IPR001664
DomainCAPS

CADPS CADPS2

7.95e-0521672IPR033227
DomainARHGEF5_35

ARHGEF5 ARHGEF35

7.95e-0521672PF15441
DomainARHGEF5/35_N

ARHGEF5 ARHGEF35

7.95e-0521672IPR029212
DomainTPR_REGION

TTC24 TTC28 TTC9B DNAH2 SRP72 MAU2 CABIN1 GPSM1

1.21e-041651678PS50293
DomainTPR

TTC24 TTC28 TTC9B DNAH2 SRP72 MAU2 CABIN1 GPSM1

1.21e-041651678PS50005
DomainTPR

TTC24 TTC28 TTC9B SRP72 MAU2 CABIN1 GPSM1

1.61e-041291677SM00028
Domain-

PDS5B COPB1 USP9X CIP2A LRRK2 RICTOR INTS4 RIC8A HEATR3

1.78e-0422216791.25.10.10
DomainTPR_repeat

TTC24 TTC28 TTC9B SRP72 MAU2 CABIN1 GPSM1

1.95e-041331677IPR019734
DomainPH

ARHGEF5 RALGPS2 SPTBN4 ARHGEF40 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

2.06e-0427816710SM00233
DomainPH_DOMAIN

ARHGEF5 RALGPS2 SPTBN4 ARHGEF40 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

2.13e-0427916710PS50003
DomainPH_domain

ARHGEF5 RALGPS2 SPTBN4 ARHGEF40 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

2.19e-0428016710IPR001849
DomainPH

ARHGEF5 RALGPS2 SPTBN4 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

2.24e-042291679PF00169
DomainSerum_albumin/AFP/Afamin

AFM ALB

2.37e-0431672IPR021177
DomainSUZ

ARPP21 R3HDM1

2.37e-0431672PF12752
DomainDH_1

ARHGEF5 ARHGEF38 ARHGEF40 PLEKHG3 ARHGEF26

2.49e-04631675PS00741
DomainRhoGEF

ARHGEF5 ARHGEF38 ARHGEF40 PLEKHG3 ARHGEF26

4.08e-04701675PF00621
DomainDH_2

ARHGEF5 ARHGEF38 ARHGEF40 PLEKHG3 ARHGEF26

4.08e-04701675PS50010
Domain-

ARHGEF5 ARHGEF38 ARHGEF40 PLEKHG3 ARHGEF26

4.35e-047116751.20.900.10
DomainDH-domain

ARHGEF5 ARHGEF38 ARHGEF40 PLEKHG3 ARHGEF26

4.35e-04711675IPR000219
DomainALBUMIN

AFM ALB

4.71e-0441672SM00103
DomainSerum_albumin_N

AFM ALB

4.71e-0441672IPR014760
DomainSUZ

ARPP21 R3HDM1

4.71e-0441672IPR024771
DomainSerum_albumin_CS

AFM ALB

4.71e-0441672IPR020857
DomainALBUMIN_2

AFM ALB

4.71e-0441672PS51438
DomainSUZ

ARPP21 R3HDM1

4.71e-0441672PS51673
DomainALBUMIN_1

AFM ALB

4.71e-0441672PS00212
DomainSerum_albumin

AFM ALB

4.71e-0441672PF00273
DomainSerum_albumin-like

AFM ALB

7.81e-0451672IPR020858
DomainNa/ntran_symport_orphan

SLC6A18 SLC6A19

7.81e-0451672IPR002438
DomainDUF1041

CADPS CADPS2

7.81e-0451672SM01145
DomainSpectrin

SYNE1 SPTBN4 DST

1.09e-03231673PF00435
DomainACTININ_2

SYNE1 SPTBN4 DST

1.09e-03231673PS00020
DomainACTININ_1

SYNE1 SPTBN4 DST

1.09e-03231673PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN4 DST

1.09e-03231673IPR001589
DomainHNOB_dom_associated

GUCY1A1 GUCY2F

1.16e-0361672IPR011645
DomainFAD-bd

RNLS MICAL2

1.16e-0361672IPR002938
DomainFAD_binding_3

RNLS MICAL2

1.16e-0361672PF01494
DomainHNOBA

GUCY1A1 GUCY2F

1.16e-0361672PF07701
DomainALB/AFP/VDB

AFM ALB

1.16e-0361672IPR000264
DomaincEGF

FBLN5 EFEMP2 MATN4

1.57e-03261673PF12662
DomaincEGF

FBLN5 EFEMP2 MATN4

1.57e-03261673IPR026823
DomainPH_dom-like

ARHGEF5 RALGPS2 MYO1B SPTBN4 ARHGEF40 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

1.60e-0342616711IPR011993
DomainMunc13_1

CADPS CADPS2

1.62e-0371672IPR014770
DomainMHD1

CADPS CADPS2

1.62e-0371672PS51258
DomainDUF1041

CADPS CADPS2

1.62e-0371672PF06292
DomainCAPS_dom

CADPS CADPS2

1.62e-0371672IPR010439
DomainSpectrin_repeat

SYNE1 SPTBN4 DST

2.16e-03291673IPR002017
DomainTPR-contain_dom

TTC24 TTC28 TTC9B SRP72 CABIN1 GPSM1

2.32e-031501676IPR013026
Domain-

TTC24 TTC28 TTC9B SRP72 MAU2 CABIN1 GPSM1

2.64e-0320716771.25.40.10
DomainCH

SYNE1 SPTBN4 DST MICAL2

2.73e-03651674SM00033
DomainMYTH4

ARHGAP39 PLEKHH2

2.75e-0391672PS51016
DomainR3H

ARPP21 R3HDM1

2.75e-0391672SM00393
DomainMyTH4

ARHGAP39 PLEKHH2

2.75e-0391672SM00139
DomainMyTH4_dom

ARHGAP39 PLEKHH2

2.75e-0391672IPR000857
DomainMyTH4

ARHGAP39 PLEKHH2

2.75e-0391672PF00784
Domain-

ARHGEF5 RALGPS2 SPTBN4 ARHGEF40 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

2.78e-03391167102.30.29.30
DomainSPEC

SYNE1 SPTBN4 DST

2.88e-03321673SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTBN4 DST

2.88e-03321673IPR018159
DomainRhoGEF

ARHGEF5 ARHGEF38 PLEKHG3 ARHGEF26

3.22e-03681674SM00325
DomainTPR_7

TTC24 TTC28

3.41e-03101672PF13176
DomainCH

SYNE1 SPTBN4 DST MICAL2

3.57e-03701674PF00307
Domain-

HEXA LCT AGL

3.72e-033516733.20.20.80
Domain-

SYNE1 SPTBN4 DST MICAL2

3.76e-037116741.10.418.10
DomainR3H

ARPP21 R3HDM1

4.15e-03111672PS51061
DomainR3H

ARPP21 R3HDM1

4.15e-03111672PF01424
Domain-

ARPP21 R3HDM1

4.15e-031116723.30.1370.50
DomainR3H_dom

ARPP21 R3HDM1

4.15e-03111672IPR001374
DomainCH

SYNE1 SPTBN4 DST MICAL2

4.16e-03731674PS50021
DomainCH-domain

SYNE1 SPTBN4 DST MICAL2

4.58e-03751674IPR001715
DomainGlyco_hydro_catalytic_dom

HEXA LCT AGL

4.71e-03381673IPR013781
DomainEGF_CA

FBLN5 EFEMP2 MATN4 FAT2 NOTCH1

4.82e-031221675SM00179
DomainTPR-like_helical_dom

TTC24 TTC28 TTC9B SRP72 MAU2 CABIN1 GPSM1

5.05e-032331677IPR011990
DomainEGF-like_Ca-bd_dom

FBLN5 EFEMP2 MATN4 FAT2 NOTCH1

5.16e-031241675IPR001881
DomainEGF_CA

FBLN5 EFEMP2 MATN4 NOTCH1

7.42e-03861674PF07645
DomainTPR_1

TTC24 TTC28 SRP72 GPSM1

8.68e-03901674IPR001440
DomainTPR_1

TTC24 TTC28 SRP72 GPSM1

8.68e-03901674PF00515
PathwayREACTOME_COHESIN_LOADING_ONTO_CHROMATIN

PDS5B WAPL MAU2

6.74e-05101193M27178
PathwayREACTOME_COHESIN_LOADING_ONTO_CHROMATIN

PDS5B WAPL MAU2

6.74e-05101193MM14892
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

9.22e-05871196MM15351
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF5 ARHGEF38 ARHGEF40 ARHGEF35 ARHGEF26

1.37e-04591195M11215
PathwayREACTOME_MITOTIC_TELOPHASE_CYTOKINESIS

PDS5B WAPL MAU2

1.58e-04131193MM15363
PathwayREACTOME_MITOTIC_TELOPHASE_CYTOKINESIS

PDS5B WAPL MAU2

1.58e-04131193M27661
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

STARD13 PDS5B FAM184B KRT10 STIM2 TTC24 KRT13 KRT15 KRT17 SYNE1 KIF21A SIPA1L3 FBF1 DNAH2 SRP72 MYO1B SPG11 MYNN PFKM RRBP1 PALB2 TASOR2 SPTBN4 USP8 DST SNX25 PHF14 BSN CADPS2 SFN

2.56e-1114421723035575683
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

KRT9 KRT10 STIM2 KRT17 EFCAB6 TTC28 COPB1 CCDC30 SEC24A LRRK2 MUC16 RICTOR TASOR2 BLM DST WDR11 PLEKHM2 CDK5RAP2 ALB XPO7

2.10e-097771722035844135
Pubmed

The genomic organization of type I keratin genes in mice.

KRT10 KRT13 KRT15 KRT17 KRT32

8.05e-0915172510087197
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

GNL3L VEZT SDCCAG8 SIPA1L3 TUSC3 ARHGEF38 VPS54 ARHGAP39 RRBP1 TASOR2 SPTBN4 POGLUT1 WDR11 GUCY1A1 INF2 PTPRR MICAL2 PLEKHG3 TBCK PHF14 TNFRSF19 IGSF9B PATJ POLK ARHGEF26 XPO7

2.33e-0814891722628611215
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CACNA1B COPB1 LRRK2 FYCO1 PFKM MYO5C TAF6L CDK5RAP2 CARD11 BSN

9.72e-082081721033230847
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32 USP9X USP9Y AGO1 STON2 SFN

1.01e-072661721119380743
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WAPL TTC28 COPB1 USP9X SYNE1 KIF21A SIPA1L3 EFEMP2 MYNN MSH3 VPS54 RRBP1 USP9Y STAT6 SPTBN4 USP8 DST CADPS MICAL2 FBXO7 R3HDM1 CADPS2 CABIN1

1.06e-0712851722335914814
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

STARD13 PDS5B WAPL ANKFY1 GNL3L COPB1 AHCTF1 KIF21A MYO1B RICTOR MSH3 PFKM RRBP1 MTPAP BLM ARHGEF40 DST WDR11 INF2 MICAL2 PLEKHG3 CHTF18 RIC8A

2.62e-0713531722329467282
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT9 KRT10 KRT13 GNL3L KRT15 KRT17 AHCTF1 SIPA1L3 WDR18 SRP72 MYO1B RRBP1 MTPAP TASOR2 TXLNA DST WDR11 PLEKHG3 STON2 ALB PATJ SFN

3.00e-0712571722236526897
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANKFY1 USP9X SYNE1 KIF21A SIPA1L3 MCC WDR18 FYCO1 ARHGAP39 SPTBN4 TXLNA DST AGO1 STON2 CDK5RAP2 BSN CABIN1 ARHGEF26 GOLGA1

3.47e-079631721928671696
Pubmed

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.

KRT9 KRT10 KRT13 KRT15 KRT17 ALB

3.95e-0757172631862882
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

STIM2 TTC28 COPB1 USP9X CIP2A SEC24A AHCTF1 SRP72 MYO1B RICTOR ARHGAP39 RRBP1 DST PATJ ARHGEF26 NOTCH1

5.31e-077081721639231216
Pubmed

A protein interaction landscape of breast cancer.

TTC28 KRT32 USP9X CIP2A SIPA1L3 MYO1B E2F4 MSH3 RRBP1 PALB2 DST MICAL2 RIC8A NUP188 XPO7

6.92e-076341721534591612
Pubmed

New consensus nomenclature for mammalian keratins.

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

7.21e-0763172616831889
Pubmed

Inverse relationship of skeletal muscle glycogen from wild-type and genetically modified mice to their phosphorylase a activity.

PFKM AGL PYGM

1.18e-065172311785984
Pubmed

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.

KRT10 KRT15 KRT17 KRT32

1.31e-0617172411371349
Pubmed

DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.

KRT9 KRT10 KRT13 KRT17 KRT32 MYO1B ORM1 ALB SFN

3.16e-06238172935864588
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

THSD7A TTC28 SPTBN4 DST CADPS CDK5RAP2 CADPS2

4.06e-06130172712421765
Pubmed

The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells.

KRT10 KRT15 KRT17

4.10e-067172316818453
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

WAPL GNL3L TTC28 ARHGEF5 SRP72 RICTOR RRBP1 TXLNA ARHGEF40 DST WDR11 CHTF18 PATJ HEATR3

4.86e-066501721438777146
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

KRT9 KRT10 KRT13 KRT17 DST PYGM ALB

5.21e-06135172729859926
Pubmed

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.

KRT9 KRT10 KRT13 KRT17 SRP72 ALB

6.31e-0691172634445801
Pubmed

14-3-3σ controls corneal epithelium homeostasis and wound healing.

KRT10 NOTCH1 SFN

6.54e-068172321228373
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STIM2 THSD7A CIP2A SIPA1L3 PER1 RICTOR ARHGAP39 FAT2 WDR11 PLEKHG3 PHF14 PLEKHH2

7.03e-064931721215368895
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

KANSL1L KRT10 ANKFY1 KRT17 SYNE1 SRP72 DST CLIC5 AGL INTS4 CDK5RAP2 PYGM

7.63e-064971721223414517
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PDS5B CWF19L2 KRT9 KRT10 SYNE1 BCKDK WDR18 SRP72 MYO1B ARHGAP39 USP9Y ZSCAN29 BLM NWD2 DST AGO1 INTS4 ALB

7.73e-0610821721838697112
Pubmed

microRNA-184 Induces a Commitment Switch to Epidermal Differentiation.

KRT10 KRT15 NOTCH1

9.77e-069172329198823
Pubmed

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ.

KRT10 KRT13 KRT15 KRT32

1.08e-0528172432674056
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

ARHGEF5 SIPA1L3 RALGPS2 RICTOR USP8 SFN

1.22e-05102172615778465
Pubmed

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.

KRT9 KRT10 KRT15 KRT17 NOTCH1

1.22e-0560172531220272
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

KRT10 KRT13 KRT17 ARHGEF5 DST GVINP1 CHTF18 PHF14 ALB

1.31e-05284172929459677
Pubmed

Spatiotemporal expression pattern of keratins in skin of AP-2alpha-deficient mice.

KRT10 KRT15 KRT32

1.39e-0510172310571739
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TTC28 USP9X SIPA1L3 FBF1 RALGPS2 RICTOR USP8 DST R3HDM1 PATJ NOTCH1

1.51e-054461721124255178
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ANKFY1 THSD7A TTC28 SYNE1 SIPA1L3 RRBP1 DST CADPS

1.76e-05225172812168954
Pubmed

FAM188B enhances cell survival via interaction with USP7.

KRT9 KRT10 KRT13 KRT15 USP9X

1.81e-0565172529795372
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PDS5B WAPL COPB1 SYNE1 AHCTF1 SIPA1L3 PER1 MCC WDR18 MAU2 RRBP1 MTPAP TASOR2 BLM INF2 CDK5RAP2 PYGM NUP188

1.85e-0511551721820360068
Pubmed

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment.

KRT10 KRT15 KRT17

1.90e-0511172316085486
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

FBLN5 BCKDK SRP72 FYCO1 EXOSC5 TLE1 INTS4 CDK5RAP2 HEATR3

1.91e-05298172932353859
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

KIF21A ROR1 DNAH2 MTPAP TAF6L LOXHD1 DST AGL ATAD2B PHF14 IGSF9B ALB NUP188 HEATR3

1.95e-057361721429676528
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PDS5B WAPL GNL3L COPB1 VEZT USP9X CIP2A AHCTF1 DNAH2 SRP72 ARHGEF40 INF2 RIC8A NUP188 HEATR3 XPO7

1.97e-059421721631073040
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KANSL1L SYNE1 DNAH2 STAT6 DST AGO1 PLEKHM2 BSN

2.26e-05233172837704626
Pubmed

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.

CADPS CADPS2

2.43e-052172218177725
Pubmed

Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer.

USP8 NOTCH1

2.43e-052172231527799
Pubmed

CARMA1 is required for Notch1-induced NF-κB activation in SIL-TAL1-negative T cell acute lymphoblastic leukemia.

CARD11 NOTCH1

2.43e-052172234223928
Pubmed

Keratin 17 is co-expressed with 14-3-3 sigma in oral carcinoma in situ and squamous cell carcinoma and modulates cell proliferation and size but not cell migration.

KRT17 SFN

2.43e-052172225736868
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

2.43e-052172212895410
Pubmed

Interaction between human serum albumin and alpha 1-acid glycoprotein in the binding of lidocaine to purified protein fractions and sera.

ORM1 ALB

2.43e-05217223795040
Pubmed

A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss.

POGLUT1 NOTCH1

2.43e-052172227807076
Pubmed

Two germline mutations can serve as genetic susceptibility screening makers for a lung adenocarcinoma family.

MCC PLEKHM2

2.43e-052172236781503
Pubmed

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

CADPS CADPS2

2.43e-052172218022372
Pubmed

CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.

CADPS CADPS2

2.43e-052172228883501
Pubmed

Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder.

SLC6A18 SLC6A19

2.43e-052172215286787
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

2.43e-05217228922996
Pubmed

Crosstalk between TLR2 and Sphk1 in microglia in the cerebral ischemia/reperfusion-induced inflammatory response.

SPHK1 TLR2

2.43e-052172229039449
Pubmed

Two distinct secretory vesicle-priming steps in adrenal chromaffin cells.

CADPS CADPS2

2.43e-052172220855507
Pubmed

FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division.

INF2 FBXO7

2.43e-052172237344480
Pubmed

CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.

CADPS CADPS2

2.43e-052172218495893
Pubmed

Evaluation of superficial oral squamous cell malignancy based on morphometry and immunoexpression of cytokeratin 13 and cytokeratin 17.

KRT13 KRT17

2.43e-052172224247036
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

2.43e-052172212925892
Pubmed

Dynamic of contribution of UBPy-sorted cargo to acrosome biogenesis: effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant.

VPS54 USP8

2.43e-052172228299521
Pubmed

TLR2 signaling and Th2 responses drive Tannerella forsythia-induced periodontal bone loss.

STAT6 TLR2

2.43e-052172221632710
Pubmed

Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.

LRRK2 MYO1B

2.43e-052172236654782
Pubmed

CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.

CADPS CADPS2

2.43e-052172225719439
Pubmed

Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes.

KRT9 KRT10

2.43e-05217227504553
Pubmed

Activator of G protein signaling 3 forms a complex with resistance to inhibitors of cholinesterase-8A without promoting nucleotide exchange on Gα(i3).

RIC8A GPSM1

2.43e-052172225480567
Pubmed

Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis.

USP8 NOTCH1

2.43e-052172237205094
Pubmed

A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.

KRT17 SFN

2.43e-052172216710422
Pubmed

Identification of a deubiquitinating enzyme as a novel AGS3-interacting protein.

USP9X GPSM1

2.43e-052172220305814
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B COPB1 USP9X AHCTF1 WDR18 SRP72 MYO1B TASOR2 BLM DST ATAD2B NUP188 XPO7

2.44e-056531721322586326
Pubmed

Airway basal cells show regionally distinct potential to undergo metaplastic differentiation.

KRT13 KRT15 KRT17

2.53e-0512172336178196
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

HEXA KRT9 KRT10 KRT13 KRT15 KRT17 FYCO1 RRBP1 RIC8A ALB NUP188 SFN

2.66e-055641721221565611
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

STIM2 TTC28 ARHGEF5 SEC24A SIPA1L3 RALGPS2 RICTOR CDR2L USP8 DST PLEKHG3 TET1 R3HDM1 PATJ SFN

2.71e-058611721536931259
Pubmed

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

ANKFY1 KRT17 USP9X MAU2 NOTCH1

3.19e-0573172530224337
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNIP2 PDS5B ANKFY1 TTC28 SYNE1 USP8 PLEKHM2 CADPS R3HDM1 XPO7

3.84e-054071721012693553
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

KRT13 COPB1 USP9X CIP2A AHCTF1 KIF21A MYO1B DST CADPS SPOCK3 RIC8A

4.14e-054981721136634849
Pubmed

Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia.

KRT10 KRT15 KRT17

4.16e-0514172316914743
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

COPB1 USP9X WDR18 MYO1B E2F4 RRBP1 TXLNA INTS4 ALB NOTCH1

4.17e-054111721036652389
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

KRT9 KRT10 KRT17 MYO1B RRBP1 DST ALB

4.91e-05191172733762435
Pubmed

Deubiquitinating enzymes: a new class of biological regulators.

USP9X USP9Y USP8

5.18e-051517239827704
Pubmed

Multiple roles of Notch signaling in the regulation of epidermal development.

KRT10 KRT15 NOTCH1

5.18e-0515172318410734
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGEF5 MCC MAU2 TASOR2 STON2 IGSF9B BSN PATJ NOTCH1 SFN

6.08e-054301721035044719
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

KRT9 KRT10 KRT13 KRT17 ALB

6.28e-0584172529563501
Pubmed

TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties.

KRT15 KRT17 SFN

6.35e-0516172336418889
Pubmed

Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1.

KRT10 KRT15 KRT17

6.35e-0516172317631878
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KRT9 KRT10 MYO1B RICTOR RRBP1 MYO5C ARHGEF40

6.99e-05202172733005030
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

KRT17 VEZT USP9X CIP2A SEC24A SIPA1L3 BCKDK MYO1B RICTOR ARHGAP39 BLM WDR11 PTPRR INTS4 CDK5RAP2 NOTCH1

7.08e-0510491721627880917
Pubmed

Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma.

ALB NOTCH1

7.27e-053172227698452
Pubmed

Arrangement of a cluster of three mouse type I keratin genes expressed sequentially during esophageal-type epithelial cell differentiation.

KRT13 KRT15

7.27e-05317227535287
Pubmed

Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin.

SLC6A18 SLC6A19

7.27e-053172226240152
Pubmed

Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism.

STAT6 TLR2

7.27e-053172218768873
Pubmed

Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility.

AFM ALB

7.27e-053172212297623
Pubmed

Comprehensive clinical and molecular analysis of 12 families with type 1 recessive cutis laxa.

FBLN5 EFEMP2

7.27e-053172222829427
Pubmed

Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.

FBLN5 EFEMP2

7.27e-053172225713297
Pubmed

Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.

CADPS CADPS2

7.27e-053172225437547
Pubmed

Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.

USP9X NOTCH1

7.27e-053172227593927
Pubmed

Immunohistochemical staining patterns of cytokeratins 13, 14, and 17 in oral epithelial dysplasia including orthokeratotic dysplasia.

KRT13 KRT17

7.27e-053172224471966
Pubmed

Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice.

KRT10 SFN

7.27e-053172212077355
Pubmed

Differential interactions and structural stability of chitosan oligomers with human serum albumin and α-1-glycoprotein.

ORM1 ALB

7.27e-053172224359035
Pubmed

Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family.

CADPS CADPS2

7.27e-053172212659812
Pubmed

An Alternative Exon of CAPS2 Influences Catecholamine Loading into LDCVs of Chromaffin Cells.

CADPS CADPS2

7.27e-053172230389842
InteractionKCNA3 interactions

CACNA1B STIM2 TTC28 COPB1 USP9X CIP2A SEC24A AHCTF1 LRRK2 SRP72 MYO1B RICTOR FYCO1 ARHGAP39 PFKM RRBP1 MYO5C TAF6L DST CDK5RAP2 CARD11 BSN PATJ ARHGEF26 NOTCH1

5.14e-0887116625int:KCNA3
GeneFamilyKeratins, type I

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

1.76e-08281136608
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF5 ARHGEF38 ARHGEF40 ARHGEF35 PLEKHG3 ARHGEF26

3.49e-06661136722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RALGPS2 SPTBN4 PLEKHM2 CADPS PLEKHG3 PLEKHH2 CADPS2 ARHGEF26

4.56e-052061138682
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC24 TTC28 TTC9B SRP72 GPSM1

7.76e-041151135769
GeneFamilyFibulins

FBLN5 EFEMP2

1.06e-0381132556
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNE1 ROR1 LRRK2 ARHGEF38 MYO1B MYO5C CLIC5 MICAL2 SNX25 PATJ CADPS2 ARHGEF26

1.42e-111941711253f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNE1 ROR1 LRRK2 ARHGEF38 MYO1B MYO5C CLIC5 MICAL2 SNX25 PATJ CADPS2

2.75e-10195171119406866f99555198a9be311fbd65751b70f35446
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT13 KRT15 KRT17 KRT32 UGT1A6 FAT2 DST SPOCK3 SFN

2.31e-081721719e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

THSD7A ROR1 MYO1B MYO5C DST CLIC5 PTPRR MICAL2 ARHGEF26

2.96e-0817717193128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ROR1 LRRK2 ARHGEF38 MYO1B MYO5C CLIC5 MICAL2 SNX25 PATJ

4.98e-081881719707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

KRT15 KRT17 MCC FAT2 DST SPOCK3 STON2 NOTCH1 SFN

5.45e-0819017194f15842b424eefadbfe451875e517cf70e29607f
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ROR1 LRRK2 ARHGEF38 MYO1B MYO5C MICAL2 SNX25 PATJ CADPS2

5.97e-081921719efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

KRT13 KRT15 KRT17 UGT1A6 FAT2 DST SPOCK3 NOTCH1 SFN

8.46e-0820017195cea84581201cee7ba8141b96e65864f4fd67113
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

KRT13 KRT15 KRT17 UGT1A6 FAT2 ARHGEF35 DST SPOCK3 SFN

8.46e-082001719592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KRT13 KRT15 KRT17 UGT1A6 FAT2 ARHGEF35 DST SPOCK3 SFN

8.46e-0820017198cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

KRT13 KRT15 KRT17 UGT1A6 FAT2 ARHGEF35 DST SPOCK3 SFN

8.46e-08200171961811380d9252f12f27b7ad4752380b52692677f
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT13 KRT15 KRT17 PANX2 FAT2 SPOCK3 NIPAL1 TNFRSF19

2.02e-07160171818ae6822915d16699beb9047baeef9b006901a35
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT13 KRT15 KRT17 PANX2 FAT2 SPOCK3 NIPAL1 TNFRSF19

2.02e-071601718830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KRT15 KRT17 UGT1A6 EFEMP2 MCC FAT2 DST SPOCK3

2.12e-071611718da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KRT15 KRT17 UGT1A6 EFEMP2 MCC FAT2 DST SPOCK3

2.12e-071611718d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ROR1 MYO1B MYO5C DST CLIC5 SNX25 PATJ ARHGEF26

3.21e-071701718e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KRT13 KRT15 KRT17 MCC FAT2 PTPRR CARD11 SFN

5.38e-071821718678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KRT13 KRT15 KRT17 MCC FAT2 PTPRR CARD11 SFN

5.38e-0718217188d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ROR1 MYO1B MYO5C DST CLIC5 MICAL2 PATJ ARHGEF26

5.85e-07184171857c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184B THSD7A MCC CLIC5 SNX25 PLEKHH2 ARHGEF26 GPSM1

5.85e-0718417187294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ROR1 MYO1B MYO5C DST CLIC5 MICAL2 PATJ ARHGEF26

5.85e-071841718d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

SIPA1L3 ROR1 MYO1B MYO5C DST CLIC5 PATJ ARHGEF26

6.09e-07185171832b4e68e551d435a732f253f6ad83408c759a642
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 THSD7A BLM PIGQ DST PTPRR TLR2 NOTCH1

6.09e-07185171887151ab95530e70d61328b336518df58db584acb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

THSD7A ROR1 MYO1B MYO5C DST CLIC5 PATJ ARHGEF26

6.61e-07187171877f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

KRT15 KRT17 UGT1A6 MCC FAT2 SPOCK3 PATJ SFN

6.61e-0718717188407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

RNLS EFCAB6 CCDC30 DNAH2 AK7 TEKT2 CFAP61 NLRC3

7.16e-0718917183e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

THSD7A ROR1 MYO1B MYO5C DST CLIC5 PATJ ARHGEF26

7.16e-0718917185a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 ARHGEF38 MYO1B MYO5C MICAL2 SNX25 PATJ CADPS2

7.75e-071911718e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

LRRK2 ARHGEF38 MYO1B MYO5C MICAL2 SNX25 PATJ CADPS2

8.06e-071921718499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell(7)_Epithelial_cells-(7)_Epithelial-H_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

KRT13 KRT15 KRT17 MCC FAT2 DST SPOCK3 STON2

8.06e-0719217187a6dd2ae217b8f8e460d47ad128904408299458c
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT13 KRT15 KRT17 KRT32 UGT1A6 FAT2 SPOCK3 SFN

8.38e-0719317187c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

RNLS EFCAB6 CCDC30 SYNE1 DNAH2 AK7 CFAP61 NLRC3

8.38e-071931718ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYNE1 LRRK2 ARHGEF38 MYO1B MICAL2 SNX25 PATJ CADPS2

8.72e-07194171897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

KRT13 KRT15 KRT17 UGT1A6 MCC FAT2 DST SPOCK3

9.78e-07197171824360b660000bdfb999d58fbf4e29585a97e1785
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT13 KRT15 KRT17 KIF21A FAT2 DST SPOCK3 SFN

9.78e-0719717185d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

KRT13 KRT15 KRT17 UGT1A6 MCC FAT2 DST SPOCK3

1.02e-0619817184235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FNIP2 LRRK2 ARHGEF38 MYO5C MICAL2 SNX25 TLR2 CADPS2

1.02e-061981718f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B SYNE1 TUSC3 SPTBN4 PTPRR CADPS MICAL2 R3HDM1

1.02e-0619817184ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FNIP2 SDCCAG8 LRRK2 ARHGEF38 MICAL2 SNX25 TLR2 CADPS2

1.02e-0619817182e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SIPA1L3 ROR1 ARHGEF38 MYO1B MYO5C MICAL2 SNX25 CADPS2

1.06e-0619917185cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KRT15 KRT17 UGT1A6 FAT2 DST SPOCK3 NOTCH1 SFN

1.06e-0619917182add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT13 KRT15 KRT17 ARHGEF5 UGT1A6 FAT2 SPOCK3 SFN

1.10e-062001718afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KRT15 KRT17 ARHGEF5 FAT2 ARHGEF35 DST NIPAL1 SFN

1.10e-06200171841705bbba40eb5ddca0b223191aac1bce00163b8
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT15 KRT17 KIF21A ARHGEF38 MUC16 MYO1B MYO5C SFN

1.10e-062001718d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

KRT15 KRT17 ARHGEF5 FAT2 ARHGEF35 DST NIPAL1 SFN

1.10e-06200171853e04399d0308b40ae99fbfaa4ff62bf061822d8
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

KRT15 KRT17 ARHGEF5 FAT2 ARHGEF35 DST NIPAL1 SFN

1.10e-062001718cc8df398532c9324fd3e171000b1ea5c208cd691
ToppCellBiopsy_Other_PF-Epithelial-Basal|Biopsy_Other_PF / Sample group, Lineage and Cell type

KRT13 KRT15 KRT17 UGT1A6 TUSC3 FAT2 SPOCK3 SFN

1.10e-0620017187098ae4b0ea8ba607519eaed8577c577530fc2a1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

KRT13 KRT15 KRT17 FBF1 SPTBN4 SPOCK3 CFAP61

2.15e-061531717a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B CIP2A USP9Y NWD2 GUCY2F SPOCK3 MYLK4

3.15e-061621717bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM184B KRT13 KRT15 KRT17 KRT32 DST SFN

4.00e-061681717f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

KRT13 KRT15 KRT17 UGT1A6 FAT2 DST SPOCK3

4.00e-06168171748089fa2d4a0f31a72405717119b767a92571f01
ToppCell15-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

KRT13 KRT15 KRT17 FAT2 SPHK1 STON2 SFN

4.33e-06170171761f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DST CLIC5 GUCY1A1 SPOCK3 TLE1 TNFRSF19 C13orf42

4.33e-0617017176c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT17 SEC24A RALGPS2 MATN4 IGSF9B ALB SFN

4.50e-061711717c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT17 SEC24A RALGPS2 MATN4 IGSF9B ALB SFN

4.50e-06171171755b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A ROR1 MYO1B MYO5C CLIC5 PATJ ARHGEF26

4.85e-061731717b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT13 KRT15 KRT17 MUC16 PANX2 FAT2 SFN

5.04e-061741717207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

ROR1 MYO1B MYO5C DST CLIC5 PATJ ARHGEF26

5.04e-061741717548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24A BCKDK RALGPS2 AK7 CHTF18 R3HDM1 SFN

5.64e-061771717c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

KRT13 KRT15 KRT17 FAT2 PLEKHG3 STON2 SFN

5.64e-061771717a0c7d08469c513cecf87777c19876884f1511570
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24A BCKDK RALGPS2 AK7 CHTF18 R3HDM1 SFN

5.64e-061771717ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT15 KRT17 UGT1A6 MCC FAT2 SPOCK3 SFN

5.64e-061771717cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A MYO1B CLIC5 INF2 SNX25 ARHGEF26 GPSM1

5.85e-061781717edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

ROR1 MYO1B MYO5C CLIC5 MICAL2 PATJ ARHGEF26

6.07e-061791717a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A ROR1 MYO1B MYO5C CLIC5 PATJ ARHGEF26

6.07e-061791717cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A ROR1 MYO1B MYO5C CLIC5 PATJ ARHGEF26

6.07e-0617917174f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ROR1 LOXHD1 DST CLIC5 PTPRR PLEKHH2 ARHGEF26

6.07e-0617917171603117b52623663458a977c94bf7f9f6c1114b8
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

KRT15 KRT17 MCC FAT2 PTPRR SPOCK3 PATJ

6.07e-061791717d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT13 KRT15 KRT17 KRT32 KIF21A DST SFN

6.53e-0618117176b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCellPND07-Epithelial-Epithelial_Airway-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT13 KRT15 KRT17 KRT32 KIF21A DST SFN

6.53e-061811717f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

FNIP2 LRRK2 ARHGEF38 CLIC5 SNX25 PATJ CADPS2

6.53e-061811717c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

KRT15 KRT17 MCC MYO1B SPOCK3 PATJ SFN

6.77e-061821717759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ROR1 MYO1B MYO5C CLIC5 MICAL2 PATJ ARHGEF26

7.02e-0618317177b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184B THSD7A MCC CLIC5 SNX25 ARHGEF26 GPSM1

7.02e-0618317173c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184B THSD7A MCC CLIC5 SNX25 ARHGEF26 GPSM1

7.02e-0618317179c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

ROR1 MYO1B MYO5C CLIC5 MICAL2 PATJ ARHGEF26

7.02e-061831717942530449e9c6583705eeb8f6f12621daea57252
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LRRK2 ARHGEF38 MYO5C MICAL2 SNX25 PATJ CADPS2

7.27e-061841717369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

KRT13 ROR1 MYO1B DST CLIC5 INF2 ARHGEF26

7.27e-061841717cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_proximal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT13 KRT15 KRT17 KRT32 UGT1A6 FAT2 SFN

7.27e-061841717575de705053da8b289670b5c40c1627c0833b5ed
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

KRT13 ROR1 MYO1B DST CLIC5 INF2 ARHGEF26

7.27e-061841717bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

THSD7A ROR1 MYO1B DST CLIC5 PATJ ARHGEF26

7.27e-061841717561592edc3083fad41b91811151b442207c65dd9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF21A LRRK2 RRBP1 MYO5C MICAL2 PATJ CADPS2

7.27e-061841717ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellmild-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BTNL8 AHCTF1 RICTOR PANX2 PLEKHG3 NOTCH1 SFN

7.27e-0618417171a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROR1 MYO1B MYO5C DST CLIC5 PATJ ARHGEF26

7.53e-0618517171c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A LRRK2 ARHGEF38 MYO5C CLIC5 PATJ CADPS2

7.53e-06185171798b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A MYO1B DST CLIC5 SNX25 ARHGEF26 GPSM1

7.53e-0618517179197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EFCAB6 CCDC30 DNAH2 ARHGAP39 AK7 TEKT2 TNFRSF19

7.53e-0618517175e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A MYO1B DST CLIC5 SNX25 ARHGEF26 GPSM1

7.53e-061851717ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STIM2 KRT13 KRT15 KRT17 FAT2 AGL SFN

7.53e-061851717e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B DST CLIC5 INF2 SNX25 ARHGEF26 GPSM1

7.53e-061851717b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellControl-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

KRT15 KRT17 MCC FAT2 DST SPOCK3 STON2

7.53e-061851717d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCellE15.5-Epithelial-airway_epithelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN5 KRT15 KRT17 ARHGEF38 MYO5C TNFRSF19 SFN

7.80e-061861717bb2c7af3b1d8478c49a8626dbfd6c92c5e7adc4a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 ARHGEF38 MYO5C SNX25 TLR2 PATJ CADPS2

7.80e-0618617172ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellE15.5-Epithelial-airway_epithelial_cell-club_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN5 KRT15 KRT17 ARHGEF38 MYO5C TNFRSF19 SFN

7.80e-06186171786c809b99088d3d6c8f87785797c4beefdcddbe7
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF21A LRRK2 RRBP1 MYO5C MICAL2 PATJ CADPS2

7.80e-061861717e83718fabb057100835d3357df407f283d23fe16
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN5 KRT15 PANX2 FAT2 PLEKHM2 BSN CADPS2

8.08e-061871717ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

KRT13 MYO1B CDR2L CLIC5 MICAL2 ARHGEF26 SFN

8.08e-061871717f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

FNIP2 LRRK2 ARHGEF38 MYO5C CLIC5 PATJ CADPS2

8.08e-06187171781cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

KRT15 KRT17 ARHGEF38 MYO5C FAT2 PTPRR PATJ

8.66e-06189171784d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROR1 MYO1B DST CLIC5 MICAL2 PATJ ARHGEF26

8.96e-06190171730b50d183d7649146eb1e79b47ba897355f1998a
ComputationalGenes in the cancer module 68.

KRT13 KRT15 KRT17 KRT32

1.26e-04261094MODULE_68
ComputationalKeratin.

KRT13 KRT15 KRT17 KRT32

1.26e-04261094MODULE_298
Drugolomoucine II

KRT9 KRT10 KRT13 KRT15 KRT17

1.55e-06271705CID005494414
DrugRicinine [524-40-3]; Down 200; 24.4uM; HL60; HT_HG-U133A

KANSL1L SIPA1L3 PER1 E2F4 RRBP1 TAF6L PLEKHM2 INF2 SPOCK3 CABIN1

1.99e-06193170102505_DN
DrugNSC34533

KRT9 KRT10 KRT13 KRT15 KRT17 KRT32

3.04e-06541706CID000003512
Diseaseuterine fibroid

SYNE1 DNAH2 MYNN GUCY1A1 PTPRR NIPAL1 RIC8A HEATR3

1.73e-051991658EFO_0000731
DiseaseCutis Laxa, Autosomal Recessive, Type I

FBLN5 EFEMP2

3.11e-0521652C0268351
DiseaseCutis laxa, recessive, type I

FBLN5 EFEMP2

3.11e-0521652C0432336
DiseaseDrug habituation

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0013170
DiseaseDrug abuse

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0013146
DiseasePrescription Drug Abuse

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C4316881
DiseaseSubstance-Related Disorders

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0236969
DiseaseDrug Use Disorders

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0013222
DiseaseDrug Dependence

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C1510472
DiseaseSubstance Dependence

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0038580
DiseaseSubstance Use Disorders

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.75e-051151656C0029231
DiseaseSubstance abuse problem

FAM184B SYNE1 MYO5C WDR11 PATJ CADPS2

4.98e-051161656C0740858
Diseasecutis laxa (implicated_via_orthology)

FBLN5 EFEMP2

9.29e-0531652DOID:3144 (implicated_via_orthology)
Diseasekeratoconjunctivitis (is_marker_for)

MUC16 TLR2

9.29e-0531652DOID:9368 (is_marker_for)
DiseaseGlycogen storage disease

PFKM AGL PYGM

1.10e-04171653cv:C0017919
Diseasemean reticulocyte volume

PDS5B DNAH2 E2F4 MAU2 PIGQ USP8 SPHK1 CHTF18 ATAD2B FBXO7 INTS4 HEATR3 VPS37D XPO7

1.70e-0479916514EFO_0010701
DiseaseIminoglycinuria

SLC6A18 SLC6A19

1.85e-0441652C0268654
DiseaseSquamous cell carcinoma of esophagus

KRT13 KRT17 FAT2 NOTCH1 SFN

1.99e-04951655C0279626
DiseasePachyonychia Congenita

KRT10 KRT17

3.07e-0451652C0265334
DiseaseCutis laxa, autosomal recessive

FBLN5 EFEMP2

3.07e-0451652cv:C3665335
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

IQANK1 KRT9 ARHGAP39 USP8 PTPRR CDK5RAP2 VPS37D

4.12e-042391657EFO_0010934
DiseaseGlycogen Storage Disease

PFKM AGL PYGM

4.55e-04271653C0017919
DiseaseCutis Laxa

FBLN5 EFEMP2

4.59e-0461652C0010495
Diseasecholangiocarcinoma (is_marker_for)

MUC16 PANX2 ALB NOTCH1

4.61e-04641654DOID:4947 (is_marker_for)
DiseaseMYELODYSPLASTIC SYNDROME

PALB2 BLM SPHK1 TLR2

5.49e-04671654C3463824
DiseaseAcute lymphocytic leukemia

BLM NOTCH1

6.41e-0471652C0023449
DiseaseSquamous cell carcinoma of lung

GUCY2F MYLK4 NOTCH1

7.56e-04321653C0149782
Diseaseserum IgG glycosylation measurement

CDO1 CWF19L2 THSD7A EFCAB6 IFI44 NXPE1 PTPRR CADPS PHF14 C13orf42

7.59e-0452316510EFO_0005193
Diseaselactase-phlorizin hydrolase measurement

LCT R3HDM1

8.51e-0481652EFO_0801753
DiseaseDrug toxicity

ORM1 AFM TLR2 ALB

1.28e-03841654C0013221
DiseaseAdverse reaction to drug

ORM1 AFM TLR2 ALB

1.28e-03841654C0041755
DiseaseBRCA2 mutation carier statu

STARD13 ETAA1

1.36e-03101652EFO_0011022
Diseasedry eye syndrome (is_marker_for)

MUC16 TLR2

1.36e-03101652DOID:10140 (is_marker_for)
Diseasesystolic blood pressure, self reported educational attainment

THSD7A CADPS

1.36e-03101652EFO_0004784, EFO_0006335
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

KRT32 ROR1 LRRK2 SPTBN4 CARD11

1.50e-031481655C0279702
Diseasethrombin generation potential measurement

SYCP2L ORM1

1.65e-03111652EFO_0005538
DiseaseAshkenazi Jewish disorders

HEXA BLM

1.65e-03111652cv:CN118946
DiseaseProteinuria

MUC16 INF2 ALB

1.80e-03431653C0033687
Diseaseend stage renal disease (is_marker_for)

RNLS TLR2 ALB

2.18e-03461653DOID:783 (is_marker_for)
DiseaseAcute kidney injury

ORM1 AFM TLR2 ALB

2.53e-031011654C2609414
DiseaseAcute Kidney Insufficiency

ORM1 AFM TLR2 ALB

2.53e-031011654C1565662
DiseaseKidney Failure, Acute

ORM1 AFM TLR2 ALB

2.53e-031011654C0022660
Diseaseomega-6:omega-3 polyunsaturated fatty acid ratio

MAU2 CFAP61 VPS37D

2.78e-03501653EFO_0010732
DiseaseHepatomegaly

GPR155 MYO1B ALB

3.46e-03541653C0019209
DiseaseCongenital total cataract

SIPA1L3 FYCO1

3.54e-03161652C0266539
DiseaseKeratoderma, Palmoplantar

KRT9 KRT10

3.54e-03161652C4551675
DiseasePolyposis, Adenomatous Intestinal

MCC MSH3

3.54e-03161652C2713442
DiseaseFamilial Intestinal Polyposis

MCC MSH3

3.54e-03161652C2713443
DiseaseRespiratory Distress Syndrome, Adult

FBLN5 LCT ALB

3.64e-03551653C0035222
Diseasemean corpuscular hemoglobin concentration

PDS5B TTC28 MYO1B MYNN MAU2 PFKM PIGQ CHTF18 ATAD2B FBXO7 RIC8A HEATR3 VPS37D XPO7

3.77e-03110516514EFO_0004528
Diseaserenal fibrosis (implicated_via_orthology)

STAT6 TLR2

4.00e-03171652DOID:0050855 (implicated_via_orthology)
DiseaseAdenomatous Polyposis Coli

MCC MSH3

4.00e-03171652C0032580
Diseasereaction time measurement

GPR155 STIM2 KRT17 TTC28 LRRK2 MCC MSH3 ATAD2B TET1 VPS37D

4.05e-0365816510EFO_0008393
DiseaseMalignant neoplasm of skin

KRT10 KRT17 NOTCH1

4.44e-03591653C0007114
DiseaseSkin Neoplasms

KRT10 KRT17 NOTCH1

4.44e-03591653C0037286
Diseaseangiopoietin-related protein 1 measurement

UGT1A6 RALGPS2

4.48e-03181652EFO_0801382
Diseaseresponse to antipsychotic drug

ARHGEF38 RNASE10 CDK5RAP2

4.65e-03601653GO_0097332
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

MSH3 PALB2

4.99e-03191652C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

MSH3 PALB2

4.99e-03191652C2936783
DiseaseSquamous cell carcinoma

KRT10 BLM NOTCH1 SFN

5.26e-031241654C0007137

Protein segments in the cluster

PeptideGeneStartEntry
YSDCQELLNQLDQRF

AGBL5

161

Q8NDL9
DNDIRACINTLQFLY

CHTF18

546

Q8WVB6
AALSALCYIRSQLEN

ADAD2

171

Q8NCV1
EQLLNNLCARYDENL

CFAP61

1121

Q8NHU2
TAVLQEYSELERQLC

CDR2L

221

Q86X02
RADLAKYICENQDSI

ALB

281

P02768
QQRLVSELIACEQDY

ARHGEF40

1086

Q8TER5
LSCEERNLLSVAYKN

SFN

36

P31947
FNINDQSLIYTLTCR

BTNL8

421

Q6UX41
EKCQAYESNRESLLN

AFM

146

P43652
RKCNATQEYDINLLE

ARHGEF38

591

Q9NXL2
LSATQQSELRDVCDY

ARHGEF5

56

Q12774
YCTEQLAEVRQQSAE

GVINP1

371

Q7Z2Y8
RFTADELQILTYQLC

AGO1

771

Q9UL18
LSATQQSELRDVCDY

ARHGEF35

56

A5YM69
RTQDCLQYLQELLAL

C13orf42

81

A0A1B0GVH6
YSLRDQLLVESCDNE

ARHGEF26

706

Q96DR7
ADEAQYCQLVRQLLD

BCKDK

146

O14874
DLCCQDNGRTLEVYQ

BCO2

371

Q9BYV7
RLQNLRASCEALYSE

CACNA1B

776

Q00975
YSSTQDQQLCAAELQ

CLIC5

111

Q9NZA1
NSRLLEDSNICNETY

ARPP21

311

Q9UBL0
SYLSICLEENNRFQV

CDK5RAP2

631

Q96SN8
NTLLIYDNVNSCLLS

NWD2

1031

Q9ULI1
RIFSQDSLCSQENYI

R3HDM1

296

Q15032
DSLCSQENYIIDKRL

R3HDM1

301

Q15032
LEQYQLCALAINDEC

PDS5B

901

Q9NTI5
RDELYIQLCRQTTEN

ARHGAP39

781

Q9C0H5
QACKLLSDDYEQVRS

INTS4

236

Q96HW7
NCIRFYQTAEELNAS

ANKFY1

166

Q9P2R3
IDQINRSLENYEPCS

POGLUT1

36

Q8NBL1
CLEQAALVNYSRLSE

CADPS

841

Q9ULU8
NGAETRVDLLCTYLQ

MUC16

13986

Q8WXI7
SYLLCISENKENVRD

MSH3

366

P20585
DLDEYTLRKNVAVNC

KANSL1L

351

A0AUZ9
CQTDDIYNRNCLIEL

KIAA0100

1566

Q14667
IRAETECQNTEYQQL

KRT10

421

P13645
VYLEIDNRQCVQASS

NOTCH1

1676

P46531
FVLQQDQRSCRAIDY

MATN4

286

O95460
ALKECRNEYERSLQN

GOLGA1

446

Q92805
YLLQVSDACAQEANL

NLRC3

606

Q7RTR2
VRQEIECQNQEYSLL

KRT9

426

P35527
QSCILAQEEEQYLQS

GPR155

636

Q7Z3F1
QLRDQAVEAQACYSL

GPSM1

281

Q86YR5
ICQINSERYLQLERA

DST

5921

Q03001
YNKLCQEVTNRERND

FYCO1

1106

Q9BQS8
AVDQLERLYSLLSQC

ATAD2B

1416

Q9ULI0
GEINTYRSLLENEDC

KRT32

391

Q14532
LEQCTSNYREDLQAL

FAM184B

616

Q9ULE4
ENTVAETECRYALQL

KRT13

346

P13646
ERLLYNCRNNTDLFE

LOXHD1

586

Q8IVV2
YLSDSELNQLRLQGC

BSN

3011

Q9UPA5
QQINCLDSILRYLES

PER1

626

O15534
LDADISEQNRQVTCY

FAT2

2931

Q9NYQ8
LRNEKCNENYTTDFI

PFKM

626

P08237
AQNCQESRESDLVKY

CWF19L2

296

Q2TBE0
DQDRALDYLSTCIDQ

COPB1

201

P53618
LVSLNLNYNCISDEL

FBXO39

226

Q8N4B4
LNYNCISDELLENLC

FBXO39

231

Q8N4B4
RLEEFNTCYNSNQLE

MYLK4

6

Q86YV6
IELNQQTCLLTLRDY

MYNN

136

Q9NPC7
LSLDLSYECQNEASL

LCT

246

P09848
CLENLTSLDVSYNLE

LRRK2

1266

Q5S007
LSDLVYLDCQNNRIR

LRRC52

76

Q8N7C0
LENSLAETECRYATQ

KRT15

346

P19012
YSDTELQQCLAAAQA

EXOSC5

201

Q9NQT4
CYAESIDDQLNTLLK

MTPAP

181

Q9NVV4
DYLIARCIDIQQSNE

RICTOR

126

Q6R327
VEYNKLCESLEELQN

PHF14

656

O94880
RELADYLCEDAQQLS

INF2

891

Q27J81
ETRLYNKCQDLESLI

PLEKHH2

81

Q8IVE3
YQACDDIERLTQQQD

ETAA1

611

Q9NY74
SVNECDNYTIRNLVL

PTPRR

521

Q15256
LEANISCSLNELTYN

PALB2

321

Q86YC2
NATALRLALQYSEQC

MCC

441

P23508
NEELSARYLSQCQEA

FBF1

651

Q8TES7
RGNYSTDQLCVLDNV

HEATR3

646

Q7Z4Q2
AQNCTISIQDYEVFR

IFI44

136

Q8TCB0
GNLAETENRYCVQLS

KRT17

326

Q04695
CASNRLISTLENLYE

BLM

771

P54132
SLERCQSLEEIQRLY

CABIN1

686

Q9Y6J0
RNVTEDVQNSCLAYV

E2F4

126

Q16254
NYSLDEIERNFCLQL

EFCAB6

281

Q5THR3
LYQSADCSDANDALI

FBXO7

186

Q9Y3I1
SERVLRENQCAYIND

CDO1

121

Q16878
LTYFLRCSELQENQL

FNIP2

521

Q9P278
EYVILNEDCQTSRAL

GUCY2F

96

P51841
LQILCNSAENELRYE

CCDC30

251

Q5VVM6
LLYNACQLDNADEQA

CADPS2

256

Q86UW7
DTIFLREYQTRQDQC

ORM1

76

P02763
EGIDDSVQLSRLCYN

AHCTF1

681

Q8WYP5
GYILLDDNRSCQDIN

FBLN5

276

Q9UBX5
QGYQLLATRLCQDID

EFEMP2

271

O95967
LDDCVIRQTNTQFQY

DNAH2

1751

Q9P225
SLLSELYCQENSVDA

MAU2

111

Q9Y6X3
RDEAQTQYSQCLIEK

CARD11

386

Q9BXL7
NENNYVLLENLECSA

NIPAL1

381

Q6NVV3
CAENVNQDNLLSYAR

MICAL2

326

O94851
GLTLNSNAELCEYLD

NXPE1

221

Q8N323
TSELNFLLQEIDNCY

PANX2

151

Q96RD6
LRIISDLQQSCEYDI

RALGPS2

236

Q86X27
EYCVLEFSQDSQQLL

PLEKHM2

931

Q8IWE5
YTLTINDDQCLLLSE

HEXA

116

P06865
LAEDVCYRLREATQN

TAF6L

36

Q9Y6J9
LDYSCSQDRDTQKIQ

USP9X

536

Q93008
QQALRYLRSNCLDQV

STARD13

681

Q9Y3M8
QRYDDCFSTNILTLI

SLC6A19

331

Q695T7
TREVYCVQANENLLS

THSD7A

461

Q9UPZ6
ALQEQARTYLDLLCS

SYNE1

4081

Q8NF91
CANTLLYENRDLETR

TMEM200B

131

Q69YZ2
FLQNLLSDERLCQSE

SNX25

601

Q9H3E2
YALNSQLLRDLDSCN

PLEKHG3

146

A1L390
LRNDLAEYQRTCEDL

SDCCAG8

246

Q86SQ7
YLNSVCQSLLDNLDL

SEC24A

521

O95486
ETILQRCNLEEISNY

GNL3L

336

Q9NVN8
VLRQRVDSCSYDLDQ

PIGQ

431

Q9BRB3
RLINLLRQSQSYCTD

SMIM14

21

Q96QK8
RQEYLKDLAENCVSN

SIPA1L3

821

O60292
NVELCRDQAQYGLTD

TEKT2

326

Q9UIF3
DVNVNLYNLQDSCRR

AGMAT

126

Q9BSE5
SYLDRTEQLQAVLCS

WDR18

371

Q9BV38
ELQQAYCELSRRISE

IQANK1

331

A8MXQ7
LASRLTLNCQNSYVE

SPG21

196

Q9NZD8
DECLAVYRDLVRNSQ

SRP72

126

O76094
RQSLQALACYADISV

RIC8A

86

Q9NPQ8
CSYTDLQLINAEEQT

STON2

166

Q8WXE9
TNDYEHCLDRNILSL

SLC6A18

316

Q96N87
RNNEVEYCNQLLDSS

TET1

1041

Q8NFU7
EYQALTFLTRNEILC

CIB4

16

A0PJX0
DIETRDCLQNTYNLN

CIP2A

86

Q8TCG1
NVNALELEDSALYLC

TRBV5-8

96

A0A5A2
ENVLCQTEYIFARSN

ROR1

256

Q01973
YSCSREALQKLIDDQ

SPG11

131

Q96JI7
VSQLDCLNRDNYIRS

TLE1

521

Q04724
VCRQANEEYQILANS

TUSC3

101

Q13454
CLQEASQAYAQERQL

TTC24

176

A2A3L6
QSTLQAECDQYRSIL

RRBP1

1121

Q9P2E9
NKDYLRLDQTDRECN

RNASE10

106

Q5GAN6
VNLALENACDEATYQ

PYGM

101

P11217
NISQDALLTCRAEAY

IGSF9B

241

Q9UPX0
LISECQRQQLEAVSY

RNLS

176

Q5VYX0
AECELSRRQYAEQEL

STIM2

311

Q9P246
RLVSVNEYCLDNTSL

PATJ

736

Q8NI35
ANYQADLANITCEIA

KIF21A

641

Q7Z4S6
IDYINDSISDCQANI

KIF21A

996

Q7Z4S6
ERCESLVDIYSQLQQ

STAT6

226

P42226
DYDQQVAISEALCRL

SYCP2L

226

Q5T4T6
QYSLCQELCSELAQD

POLK

431

Q9UBT6
CEELIQQYNRAEDSI

WAPL

891

Q7Z5K2
EEQSVQLLQCYLQED

NUP188

86

Q5SRE5
ENYEESIAQLSRQCR

SPTBN4

1671

Q9H254
ILDYSCSQDRDAQKI

USP9Y

536

O00507
QLEREACLASNYALA

VPS37D

51

Q86XT2
SQLCKDINNDYLAER

TBCK

306

Q8TEA7
NVNALELDDSALYLC

TRBV5-4

96

A0A0C4DH59
SELRSIYLDKNEQCT

SPOCK3

271

Q9BQ16
GNYEQAISCLERQLN

TTC28

971

Q96AY4
LRSQDIQYNGSELSC

TNFRSF19

206

Q9NS68
QQLDQLSTIGRCEYE

XPO7

441

Q9UIA9
LENCDLEESNSRDYL

ZNF420

76

Q8TAQ5
YEQVTNEDLLTNCTL

SPHK1

126

Q9NYA1
QDLCFNLYEVELSNR

TASOR2

86

Q5VWN6
LYFINCQSLLQDRDT

UGT1A6

121

P19224
NEISRTEYLCENSLE

VEZT

656

Q9HBM0
AILSETQFYEALRNC

ZSCAN29

421

Q8IWY8
VQELTYDLRSQCDAI

WDR11

336

Q9BZH6
YISNSDLQRCVNLQA

TLR2

66

O60603
NRNCYQDDINRSNLL

USP8

806

P40818
LTACLLQSELVNYER

TTC9B

141

Q8N6N2
SRQLEDILSTYCVDN

TXLNA

76

P40222
ANNIQELLYSASDIC

VPS54

596

Q9P1Q0
LNALYTRFDQQCGEL

GUCY1A1

506

Q02108
LAELNQILYRCESEE

AGL

901

P35573
RENAYLTKDLTQDCL

AK7

306

Q96M32
AYRSLRDQDKDQCIL

MYO1B

91

O43795
CLNNFDLSEYRQILS

MYO5C

1476

Q9NQX4