Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	telomeric repeat-containing RNA binding	HNRNPA1L2 HNRNPA1	2.75e-05	3	61	2	GO:0061752
GeneOntologyMolecularFunction	RNA strand annealing activity	HNRNPA1L2 HNRNPA1	9.13e-05	5	61	2	GO:0033592
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2A FBXL19	4.07e-04	10	61	2	GO:0045322
GeneOntologyMolecularFunction	miRNA binding	RBM4 HNRNPA1L2 HNRNPA1	4.25e-04	48	61	3	GO:0035198
GeneOntologyMolecularFunction	G-rich strand telomeric DNA binding	HNRNPA1L2 HNRNPA1	4.96e-04	11	61	2	GO:0098505
GeneOntologyMolecularFunction	DNA/DNA annealing activity	HNRNPA1L2 HNRNPA1	4.96e-04	11	61	2	GO:1990814
GeneOntologyMolecularFunction	histone modifying activity	KAT7 KMT2A PRMT9 FBXL19 PHF10	6.70e-04	229	61	5	GO:0140993
GeneOntologyMolecularFunction	single-stranded telomeric DNA binding	HNRNPA1L2 HNRNPA1	7.01e-04	13	61	2	GO:0043047
GeneOntologyMolecularFunction	annealing activity	HNRNPA1L2 HNRNPA1	8.16e-04	14	61	2	GO:0140666
GeneOntologyMolecularFunction	protein serine kinase activity	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	8.28e-04	363	61	6	GO:0106310
GeneOntologyMolecularFunction	regulatory RNA binding	RBM4 HNRNPA1L2 HNRNPA1	9.02e-04	62	61	3	GO:0061980
GeneOntologyMolecularFunction	sequence-specific single stranded DNA binding	HNRNPA1L2 HNRNPA1	9.40e-04	15	61	2	GO:0098847
GeneOntologyMolecularFunction	pre-mRNA binding	RBM4 HNRNPA1L2 HNRNPA1	9.90e-04	64	61	3	GO:0036002
GeneOntologyMolecularFunction	sequence-specific mRNA binding	HNRNPA1L2 HNRNPA1	1.52e-03	19	61	2	GO:1990825
GeneOntologyMolecularFunction	protein kinase activity	CSNK1G3 SPEG CAMK2G GUCY2D TAOK1 STK32C WNK4	2.29e-03	600	61	7	GO:0004672
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	2.36e-03	446	61	6	GO:0004674
GeneOntologyMolecularFunction	protein homodimerization activity	DAB2IP CHMP4C MLXIPL CAMK2G GUCY2D LRP4 KMT2A MSH3	3.23e-03	815	61	8	GO:0042803
GeneOntologyMolecularFunction	protein dimerization activity	DAB2IP CHMP4C RALGAPA1 MLXIPL ANO2 CAMK2G GUCY2D LRP4 KMT2A MSH3	3.33e-03	1205	61	10	GO:0046983
GeneOntologyMolecularFunction	alpha-actinin binding	ALMS1 PDLIM2	4.03e-03	31	61	2	GO:0051393
GeneOntologyBiologicalProcess	alternative mRNA splicing, via spliceosome	KHDRBS1 RBM4 RBM15B HNRNPA1L2 HNRNPA1	3.36e-06	79	60	5	GO:0000380
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	KHDRBS1 RBM4B RBM4 RBM15B HNRNPA1L2 SRRM2 HNRNPA1 HNRNPA1L3	8.87e-06	358	60	8	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	KHDRBS1 RBM4B RBM4 RBM15B HNRNPA1L2 SRRM2 HNRNPA1 HNRNPA1L3	8.87e-06	358	60	8	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	KHDRBS1 RBM4B RBM4 RBM15B HNRNPA1L2 SRRM2 HNRNPA1 HNRNPA1L3	9.62e-06	362	60	8	GO:0000375
GeneOntologyBiologicalProcess	vestibular nucleus development	CACNA1A KCNE1	2.49e-05	3	60	2	GO:0021750
GeneOntologyBiologicalProcess	regulation of alternative mRNA splicing, via spliceosome	KHDRBS1 RBM4 RBM15B HNRNPA1	2.61e-05	59	60	4	GO:0000381
GeneOntologyBiologicalProcess	mRNA processing	KHDRBS1 RBM4B RBM4 RBM15B PRMT9 HNRNPA1L2 SRRM2 HNRNPA1 HNRNPA1L3	2.85e-05	551	60	9	GO:0006397
GeneOntologyBiologicalProcess	response to potassium ion	KMT2A HNRNPA1L2 HNRNPA1	3.00e-05	21	60	3	GO:0035864
GeneOntologyBiologicalProcess	axonal transport	BLOC1S1 MGARP DCTN1 KIF1C	6.74e-05	75	60	4	GO:0098930
GeneOntologyBiologicalProcess	medulla oblongata development	CACNA1A KCNE1	8.27e-05	5	60	2	GO:0021550
GeneOntologyBiologicalProcess	RNA splicing	KHDRBS1 RBM4B RBM4 RBM15B HNRNPA1L2 SRRM2 HNRNPA1 HNRNPA1L3	9.81e-05	502	60	8	GO:0008380
GeneOntologyBiologicalProcess	axo-dendritic transport	BLOC1S1 MGARP DCTN1 KIF1C	1.91e-04	98	60	4	GO:0008088
GeneOntologyBiologicalProcess	regulation of mitotic spindle organization	CHMP4C DCTN1 ANKRD53	2.85e-04	44	60	3	GO:0060236
GeneOntologyBiologicalProcess	regulation of spindle organization	CHMP4C DCTN1 ANKRD53	3.69e-04	48	60	3	GO:0090224
GeneOntologyCellularComponent	nucleoplasmic periphery of the nuclear pore complex	HNRNPA1L2 HNRNPA1	1.17e-04	6	59	2	GO:1990826
GeneOntologyCellularComponent	catalytic step 2 spliceosome	HNRNPA1L2 SRRM2 HNRNPA1 HNRNPA1L3	1.63e-04	97	59	4	GO:0071013
MousePheno	tongue muscle hypoplasia	HNRNPA1L2 HNRNPA1	1.20e-05	2	49	2	MP:0030421
MousePheno	abnormal cardiac mesenchyme morphology	ANKRD17 FBXL19	7.19e-05	4	49	2	MP:0011264
Domain	cwf21	U2SURP SRRM2	9.81e-06	2	59	2	PF08312
Domain	mRNA_splic_Cwf21_dom	U2SURP SRRM2	9.81e-06	2	59	2	IPR013170
Domain	HnRNPA1	HNRNPA1L2 HNRNPA1	2.94e-05	3	59	2	PF11627
Domain	HnRNPA1	HNRNPA1L2 HNRNPA1	2.94e-05	3	59	2	IPR021662
Domain	RRM_1	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	4.89e-05	208	59	6	PF00076
Domain	RRM	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	6.19e-05	217	59	6	SM00360
Domain	RRM_dom	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	7.94e-05	227	59	6	IPR000504
Domain	RRM	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	8.54e-05	230	59	6	PS50102
Domain	-	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	1.18e-04	244	59	6	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	1.60e-04	258	59	6	IPR012677
Domain	Znf_CXXC	KMT2A FBXL19	5.30e-04	11	59	2	IPR002857
Domain	ZF_CXXC	KMT2A FBXL19	5.30e-04	11	59	2	PS51058
Domain	zf-CXXC	KMT2A FBXL19	5.30e-04	11	59	2	PF02008
Domain	Prot_kinase_dom	CSNK1G3 SPEG CAMK2G GUCY2D TAOK1 STK32C WNK4	8.50e-04	489	59	7	IPR000719
Domain	PROTEIN_KINASE_DOM	CSNK1G3 SPEG CAMK2G GUCY2D TAOK1 STK32C WNK4	8.91e-04	493	59	7	PS50011
Domain	Ser/Thr_kinase_AS	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	8.98e-04	357	59	6	IPR008271
Domain	S_TKc	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	9.24e-04	359	59	6	SM00220
Domain	PROTEIN_KINASE_ST	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	9.65e-04	362	59	6	PS00108
Domain	Pkinase	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	1.25e-03	381	59	6	PF00069
Domain	Kinase-like_dom	CSNK1G3 SPEG CAMK2G GUCY2D TAOK1 STK32C WNK4	1.54e-03	542	59	7	IPR011009
Domain	Znf_PHD-finger	KMT2A FBXL19 PHF10	2.00e-03	79	59	3	IPR019787
Domain	zf-CCHC	RBM4B RBM4	2.38e-03	23	59	2	PF00098
Domain	PHD	KMT2A FBXL19 PHF10	2.80e-03	89	59	3	SM00249
Domain	Znf_PHD	KMT2A FBXL19 PHF10	2.99e-03	91	59	3	IPR001965
Domain	-	RBM4B RBM4	3.04e-03	26	59	2	4.10.60.10
Domain	PROTEIN_KINASE_ATP	CSNK1G3 SPEG CAMK2G TAOK1 STK32C WNK4	3.20e-03	459	59	6	PS00107
Domain	ZF_PHD_2	KMT2A FBXL19 PHF10	3.37e-03	95	59	3	PS50016
Domain	ZF_PHD_1	KMT2A FBXL19 PHF10	3.47e-03	96	59	3	PS01359
Domain	ZF_CCHC	RBM4B RBM4	5.46e-03	35	59	2	PS50158
Domain	KH_1	KHDRBS1 ANKRD17	6.41e-03	38	59	2	PF00013
Domain	-	KHDRBS1 ANKRD17	6.74e-03	39	59	2	3.30.1370.10
Domain	Protein_kinase_ATP_BS	CSNK1G3 SPEG CAMK2G TAOK1 STK32C	6.84e-03	379	59	5	IPR017441
Domain	KH	KHDRBS1 ANKRD17	7.08e-03	40	59	2	SM00322
Domain	KH_dom	KHDRBS1 ANKRD17	7.08e-03	40	59	2	IPR004087
Domain	KH_TYPE_1	KHDRBS1 ANKRD17	7.79e-03	42	59	2	PS50084
Domain	KH_dom_type_1	KHDRBS1 ANKRD17	8.52e-03	44	59	2	IPR004088
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	RALGAPA1 KHDRBS1 RBM4B RBM4 ANKRD17 TAOK1 HNRNPA1L2 HNRNPA1 WNK4 PLPP6	7.65e-09	462	61	10	31138677
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 MLXIPL ALMS1 KCTD8 KMT2A ANKRD17 STK32C SRRM2 ARHGEF17 WNK4 KIF1C	2.72e-07	861	61	11	36931259
Pubmed	The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.	KHDRBS1 HNRNPA1L2 HNRNPA1	6.11e-07	10	61	3	21984414
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	KAT7 KHDRBS1 RBM4 U2SURP RBM15B KMT2A ANKRD17 SRRM2 DCTN1 HNRNPA1	2.04e-06	847	61	10	35850772
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	DAB2IP CACNA1A CAMK2G PITPNM3 TAOK1 SRRM2 PLPP6	2.55e-06	347	61	7	17114649
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	KHDRBS1 RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	2.55e-06	347	61	7	16033648
Pubmed	Post-translational modifications of hnRNP A1 differentially modulate retroviral IRES-mediated translation initiation.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	32960212
Pubmed	Phylogenetic and molecular characterization of the splicing factor RBM4.	RBM4B RBM4	3.03e-06	2	61	2	23527094
Pubmed	siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	15215364
Pubmed	Phosphorylation of hnRNP A1-Serine 199 Is Not Required for T Cell Differentiation and Function.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	38334757
Pubmed	HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis.	KAT7 KMT2A	3.03e-06	2	61	2	34431785
Pubmed	Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: evidence that A1 is not essential for cell growth.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	1406633
Pubmed	The LARK/RBM4a protein is highly expressed in cerebellum as compared to cerebrum.	RBM4B RBM4	3.03e-06	2	61	2	18708123
Pubmed	Novel Mutations in Two Saudi Patients with Congenital Retinal Dystrophy.	ALMS1 GUCY2D	3.03e-06	2	61	2	26957854
Pubmed	Heterogeneous nuclear ribonucleoprotein A1 regulates rhythmic synthesis of mouse Nfil3 protein via IRES-mediated translation.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	28220845
Pubmed	Identification and characterization of FBXL19 gene in silico.	KMT2A FBXL19	3.03e-06	2	61	2	15547684
Pubmed	The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x.	KHDRBS1 HNRNPA1	3.03e-06	2	61	2	17371836
Pubmed	Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	31169879
Pubmed	Regulation of mouse hepatitis virus RNA synthesis by heterogeneous nuclear ribonucleoprotein A1.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	11774503
Pubmed	Role of hnRNP A1 in coronavirus RNA synthesis.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	11774505
Pubmed	Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a patient with de novo acute myeloid leukemia.	DAB2IP KMT2A	3.03e-06	2	61	2	14978793
Pubmed	Novel Pathological Role of hnRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) in Vascular Smooth Muscle Cell Function and Neointima Hyperplasia.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	28912364
Pubmed	The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	8041722
Pubmed	hnRNP A1 dysfunction in oligodendrocytes contributes to the pathogenesis of multiple sclerosis.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	36382566
Pubmed	KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements.	KAT7 KMT2A	3.03e-06	2	61	2	32764680
Pubmed	Interplay between hnRNP A1 and a cis-acting element in the 3' UTR of CYP2A5 mRNA is central for high expression of the gene.	HNRNPA1L2 HNRNPA1	3.03e-06	2	61	2	12560094
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	LRRC34 FAT1 KHDRBS1 RBM15B SRRM2 HNRNPA1 C1orf94	3.30e-06	361	61	7	26167880
Pubmed	The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.	KHDRBS1 HNRNPA1	9.07e-06	3	61	2	20186123
Pubmed	Heterogeneous Nuclear Ribonucleoprotein A1 Improves the Intestinal Injury by Regulating Apoptosis Through Trefoil Factor 2 in Mice with Anti-CD3-induced Enteritis.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	25901972
Pubmed	Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	21454539
Pubmed	The Splicing Factor hnRNPA1 Regulates Alternate Splicing of the MYLK Gene.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	29077485
Pubmed	Molecular cloning of the genes suppressed in RVC lymphoma cells by topoisomerase inhibitors.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	8912629
Pubmed	PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	28115626
Pubmed	A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	27151978
Pubmed	Resveratrol limits epithelial to mesenchymal transition through modulation of KHSRP/hnRNPA1-dependent alternative splicing in mammary gland cells.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	28088441
Pubmed	eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	20338999
Pubmed	Quaking regulates Hnrnpa1 expression through its 3' UTR in oligodendrocyte precursor cells.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	21253564
Pubmed	LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	33115498
Pubmed	Adipocyte-Specific Hnrnpa1 Knockout Aggravates Obesity-Induced Metabolic Dysfunction via Upregulation of CCL2.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	38320300
Pubmed	HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	37525910
Pubmed	RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.	RBM4B RBM4	9.07e-06	3	61	2	27821480
Pubmed	HuR-regulated mRNAs associated with nuclear hnRNP A1-RNP complexes.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	24152440
Pubmed	Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	15390079
Pubmed	hnRNP A1 and secondary structure coordinate alternative splicing of Mag.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	23704325
Pubmed	HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	33692334
Pubmed	A novel splicing regulator shares a nuclear import pathway with SR proteins.	RBM4B RBM4	9.07e-06	3	61	2	12628928
Pubmed	Norovirus genome circularization and efficient replication are facilitated by binding of PCBP2 and hnRNP A1.	HNRNPA1L2 HNRNPA1	9.07e-06	3	61	2	23946460
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KAT7 MLXIPL YAF2 KHDRBS1 RBM4 U2SURP RBM15B KMT2A MSH3 SRRM2 HNRNPA1	1.37e-05	1294	61	11	30804502
Pubmed	Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	22345078
Pubmed	Analysis of RNA-protein interactions of mouse liver cytochrome P4502A5 mRNA.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	10215609
Pubmed	hnRNP Q and hnRNP A1 Regulate the Translation of Cofilin in Response to Transient Oxygen-Glucose Deprivation in Hippocampal Neurons.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	34944075
Pubmed	Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	33951764
Pubmed	hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.	KHDRBS1 HNRNPA1	1.81e-05	4	61	2	29396485
Pubmed	Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	12426391
Pubmed	hnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain by stabilizing TRPA1 mRNA.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	37943660
Pubmed	m6A-Induced lncRNA MEG3 Promotes Cerebral Ischemia-Reperfusion Injury Via Modulating Oxidative Stress and Mitochondrial Dysfunction by hnRNPA1/Sirt2 Axis.	HNRNPA1L2 HNRNPA1	1.81e-05	4	61	2	38358439
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	KHDRBS1 RBM4 U2SURP SRRM2 HNRNPA1	2.55e-05	197	61	5	22365833
Pubmed	Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling.	HNRNPA1L2 HNRNPA1	3.02e-05	5	61	2	18562319
Pubmed	Impact of heterogeneous nuclear ribonucleoprotein A/B subtype overexpression on the expression of cancer stem cell markers CD133 and CD44 and cellular proliferation capacity.	HNRNPA1L2 HNRNPA1	3.02e-05	5	61	2	38279469
Pubmed	The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism.	HNRNPA1L2 HNRNPA1	3.02e-05	5	61	2	20133837
Pubmed	The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis.	KHDRBS1 HNRNPA1	3.02e-05	5	61	2	24514149
Pubmed	7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts.	HNRNPA1L2 HNRNPA1	3.02e-05	5	61	2	24607481
Pubmed	cDNA cloning of human hnRNP protein A1 reveals the existence of multiple mRNA isoforms.	HNRNPA1 HNRNPA1L3	3.02e-05	5	61	2	2836799
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ALMS1 U2SURP SRRM2 ARHGEF17	3.45e-05	104	61	4	9205841
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 CACNA1A MLXIPL KHDRBS1 PRR36 CAMK2G KMT2A HNRNPA1L2 ARHGEF17 DCTN1 HNRNPA1	3.47e-05	1431	61	11	37142655
Pubmed	Stella is a maternal effect gene required for normal early development in mice.	HNRNPA1L2 HNRNPA1	4.52e-05	6	61	2	14654002
Pubmed	Identification of novel cellular genes transcriptionally suppressed by v-src.	HNRNPA1L2 HNRNPA1	4.52e-05	6	61	2	7832805
Pubmed	hCAF1, a new regulator of PRMT1-dependent arginine methylation.	KHDRBS1 HNRNPA1	4.52e-05	6	61	2	17264152
Pubmed	RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.	RBM4B RBM4	4.52e-05	6	61	2	27009199
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	YAF2 KHDRBS1 RBM4B SPEG ANKRD17 HNRNPA1L2 BLOC1S1 SRRM2 DCTN1	4.69e-05	971	61	9	33306668
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SPEG CAMK2G HNRNPA1L2 SRRM2 HNRNPA1	5.44e-05	231	61	5	16452087
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	DAB2IP YAF2 KHDRBS1 CAMK2G STK32C DCTN1 KIF1C	5.56e-05	560	61	7	21653829
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	KAT7 RBM15B KMT2A ARHGEF17	5.85e-05	119	61	4	23508102
Pubmed	LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.	RBM4B RBM4	6.32e-05	7	61	2	17264215
Pubmed	HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy.	HNRNPA1L2 HNRNPA1	6.32e-05	7	61	2	32086392
Pubmed	Comparative proteomic analysis to study molecular events during gonad development in mice.	HNRNPA1L2 HNRNPA1	6.32e-05	7	61	2	16604525
Pubmed	Isolation of epiblast-specific cDNA clones by differential hybridization with polymerase chain reaction-amplified probes derived from single embryos.	HNRNPA1L2 HNRNPA1	6.32e-05	7	61	2	1497882
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KHDRBS1 RBM4 U2SURP TAOK1 SRRM2 DCTN1 HNRNPA1	7.07e-05	582	61	7	20467437
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	KHDRBS1 U2SURP HNRNPA1L2 SRRM2 HNRNPA1	7.18e-05	245	61	5	21182205
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	KHDRBS1 RBM4B RBM4 U2SURP RBM15B SRRM2 HNRNPA1 KIF1C	8.07e-05	807	61	8	22681889
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KHDRBS1 U2SURP SRRM2 HNRNPA1	8.25e-05	130	61	4	35545047
Pubmed	RNA association and nucleocytoplasmic shuttling by ataxin-1.	HNRNPA1L2 HNRNPA1	8.42e-05	8	61	2	15615787
Pubmed	hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated.	HNRNPA1L2 HNRNPA1	8.42e-05	8	61	2	34630013
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	KAT7 KHDRBS1 KMT2A SRRM2 HNRNPA1 PHF10	8.42e-05	411	61	6	35182466
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	KAT7 KHDRBS1 U2SURP RBM15B KMT2A SRRM2 HNRNPA1	9.01e-05	605	61	7	28977666
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	KAT7 MLXIPL KHDRBS1 CAMK2G AEBP2 KMT2A ANKRD17 DCTN1 HNRNPA1 PHF10	9.69e-05	1327	61	10	32694731
Pubmed	Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.	RBM4B RBM4	1.08e-04	9	61	2	37670183
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KMT2A FBXL19	1.35e-04	10	61	2	29276034
Pubmed	T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.	KHDRBS1 HNRNPA1	1.35e-04	10	61	2	10332027
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	KAT7 CSNK1G3 RBM4 U2SURP MSH3 SRRM2 HNRNPA1	1.54e-04	660	61	7	32780723
Pubmed	Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes.	HNRNPA1L2 HNRNPA1	1.65e-04	11	61	2	36220570
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KAT7 YAF2 AEBP2 PHF10	1.71e-04	157	61	4	30186101
Pubmed	A novel SR-related protein is required for the second step of Pre-mRNA splicing.	HNRNPA1L2 HNRNPA1	1.97e-04	12	61	2	15798186
Pubmed	High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint.	CACNA1A FAT1	1.97e-04	12	61	2	9680377
Pubmed	RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development.	RBM4B RBM4	1.97e-04	12	61	2	29581187
Pubmed	The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.	HNRNPA1L2 HNRNPA1	1.97e-04	12	61	2	16236758
Pubmed	The biogenesis of the coiled body during early mouse development.	HNRNPA1L2 HNRNPA1	1.97e-04	12	61	2	7768196
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	KAT7 KHDRBS1 U2SURP SRRM2 HNRNPA1 PHF10	2.09e-04	486	61	6	30940648
Pubmed	RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.	KHDRBS1 HNRNPA1	2.33e-04	13	61	2	10749975
Pubmed	Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.	HNRNPA1L2 HNRNPA1	2.33e-04	13	61	2	28024152
Interaction	YWHAB interactions	DAB2IP CHMP4C RALGAPA1 YAF2 SPEG CAMK2G KMT2A ANKRD17 PRMT9 TAOK1 SRRM2 ARHGEF17 DCTN1 HNRNPA1 KIF1C	1.17e-07	1014	58	15	int:YWHAB
Interaction	YWHAH interactions	DAB2IP RALGAPA1 MLXIPL YAF2 ALMS1 SPEG CAMK2G RBM15B KMT2A ANKRD17 TAOK1 SRRM2 ARHGEF17 DCTN1 KIF1C	3.43e-07	1102	58	15	int:YWHAH
Interaction	YWHAG interactions	DAB2IP CHMP4C RALGAPA1 MLXIPL ALMS1 CSNK1G3 SPEG CAMK2G RBM15B KMT2A ANKRD17 TAOK1 SRRM2 ARHGEF17 KIF1C	1.65e-06	1248	58	15	int:YWHAG
Interaction	TRIM26 interactions	YAF2 RBM4 CAMK2G SRRM2 DCTN1 PHF10	2.27e-05	199	58	6	int:TRIM26
Interaction	RBM7 interactions	KHDRBS1 RBM4 PRMT9 SRRM2 HNRNPA1	3.10e-05	126	58	5	int:RBM7
Interaction	LGALS7 interactions	CHMP4C KAT7 YAF2 AEBP2 HNRNPA1	4.96e-05	139	58	5	int:LGALS7
Interaction	YWHAQ interactions	DAB2IP CHMP4C RALGAPA1 MLXIPL YAF2 SPEG KMT2A ANKRD17 TAOK1 HNRNPA1 WNK4 KIF1C	6.66e-05	1118	58	12	int:YWHAQ
Interaction	YWHAZ interactions	DAB2IP CHMP4C RALGAPA1 MLXIPL YAF2 CSNK1G3 SPEG CAMK2G KMT2A ANKRD17 DCTN1 HNRNPA1 KIF1C	7.53e-05	1319	58	13	int:YWHAZ
Interaction	OR9Q2 interactions	HNRNPA1L2 HNRNPA1	8.10e-05	5	58	2	int:OR9Q2
Interaction	FZR1 interactions	GPRASP1 YAF2 KHDRBS1 PRR36 RBM4B SPEG ANKRD17 HNRNPA1L2 BLOC1S1 SRRM2 DCTN1 HNRNPA1	1.04e-04	1172	58	12	int:FZR1
Cytoband	2p13	ALMS1 DCTN1	4.32e-04	23	61	2	2p13
Cytoband	Ensembl 112 genes in cytogenetic band chr2p13	ALMS1 DCTN1 ANKRD53	8.78e-04	140	61	3	chr2p13
GeneFamily	RNA binding motif containing	RBM4B RBM4 U2SURP RBM15B HNRNPA1L2 HNRNPA1	7.94e-06	213	41	6	725
GeneFamily	Zinc fingers CXXC-type	KMT2A FBXL19	3.26e-04	12	41	2	136
GeneFamily	PHD finger proteins	KMT2A FBXL19 PHF10	1.11e-03	90	41	3	88
GeneFamily	Zinc fingers CCHC-type\|RNA binding motif containing	RBM4B RBM4	1.46e-03	25	41	2	74
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	SPEG KCTD8 CCDC80 MGARP WNK4	5.35e-06	184	61	5	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	Mild-CD8+_T\|World / Disease group and Cell class	RBM4 KMT2A ARHGAP9 TAOK1 PDLIM2	6.92e-06	194	61	5	d64c2efb482bcdef9240977eae1023c4191286e7
Computational	Neighborhood of SUFU	RALGAPA1 RBM4B KMT2A ANKRD17	7.52e-05	77	32	4	GCM_SUFU
Computational	Neighborhood of UBE2N	RALGAPA1 KAT7 RBM4B KMT2A PHF10	8.33e-05	154	32	5	GCM_UBE2N
Computational	Neighborhood of MYST2	RALGAPA1 KAT7 RBM4B ANKRD17 PHF10	1.40e-04	172	32	5	GCM_MYST2
Computational	Neighborhood of ZNF198	RALGAPA1 KAT7 RBM4B ANKRD17	3.79e-04	117	32	4	GCM_ZNF198
Computational	Neighborhood of NCAM1	RALGAPA1 KAT7 RBM4B ANKRD17	5.17e-04	127	32	4	GCM_NCAM1
Computational	Neighborhood of DFFA	RALGAPA1 KAT7 KMT2A ANKRD17	5.49e-04	129	32	4	GCM_DFFA
Computational	Neighborhood of RAP1A	YAF2 CAMK2G MSH3 PHF10	7.47e-04	140	32	4	MORF_RAP1A
Computational	RNA splicing.	KHDRBS1 RBM4 HNRNPA1	9.24e-04	65	32	3	MODULE_183
Computational	Neighborhood of CCNF	CAMK2G MSH3 PHF10	1.57e-03	78	32	3	MORF_CCNF
Computational	Neighborhood of MAP4K4	RALGAPA1 LRP4 ANKRD17 PHF10	1.60e-03	172	32	4	GCM_MAP4K4
Computational	Neighborhood of RBM8A	KAT7 RBM4B KMT2A	1.75e-03	81	32	3	GCM_RBM8A
Computational	Neighborhood of BNIP1	YAF2 CAMK2G MSH3 PHF10	2.31e-03	190	32	4	MORF_BNIP1
Computational	Neighborhood of PPP5C	CAMK2G MSH3 PHF10	2.44e-03	91	32	3	MORF_PPP5C
Computational	Neighborhood of APEX1	KHDRBS1 U2SURP HNRNPA1	2.51e-03	92	32	3	GNF2_APEX1
Computational	Neighborhood of PPM1D	KAT7 RBM4B	2.67e-03	26	32	2	GCM_PPM1D
Disease	myopathy (implicated_via_orthology)	HNRNPA1L2 HNRNPA1 HNRNPA1L3	1.11e-04	48	57	3	DOID:423 (implicated_via_orthology)
Disease	chronic kidney disease, Proteinuria	CACNA1A KMT2A	1.99e-04	11	57	2	EFO_0003884, HP_0000093
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	CAMK2G SRRM2	4.89e-04	17	57	2	DOID:0060307 (is_implicated_in)
Disease	Noise-induced hearing loss	KCNE1 TAOK1	8.26e-04	22	57	2	C0018781
Disease	Cone-Rod Dystrophy 2	GUCY2D PITPNM3	1.44e-03	29	57	2	C3489532
Disease	level of Sphingomyelin (d42:2) in blood serum	MLXIPL ANKRD17	1.44e-03	29	57	2	OBA_2045183
Disease	Ovarian Mucinous Adenocarcinoma	SPEG WNK4	1.64e-03	31	57	2	C1335167
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	MLXIPL LINC-PINT LRP4	1.92e-03	127	57	3	EFO_0008595, EFO_0020947

Protein segments in the cluster

Peptide	Gene	Start	Entry
MSTGPTAATGSNRRL	VAMP3	1	Q15836
RSPSGMRQGRTSERS	C2orf16	1886	Q68DN1
TGGHSSGRSPRMERR	CACNA1A	2356	O00555
SSATSGGRRGSLEMS	AEBP2	196	Q6ZN18
MSNSRPRSRRDAGGG	PRMT9	1	Q6P2P2
RTPSGSRMSAEASAR	DCTN1	11	Q14203
MAPGSRGERSSFRSR	BLOC1S1	1	P78537
SMGRPSSTLGVNRSS	ALMS1	2846	Q8TCU4
RRRMASGNGLPSSSA	C1orf94	21	Q6P1W5
GGDRSRSRAASSAPS	ANO2	971	Q9NQ90
GSSRARSASSPRGMV	ANKRD17	41	O75179
PGMSSTARRSRAASS	CHMP4C	201	Q96CF2
EGSSARSRMLRFPSG	CCDC80	121	Q76M96
MSSSSRGPGAGARRR	FBXL19	21	Q6PCT2
MASASSSQRGRRGSG	HNRNPA1L2	186	Q32P51
MASASSSQRGRSGSG	HNRNPA1L3	141	A0A2R8Y4L2
MKRQSERDSSPSGRG	RBM15B	1	Q8NDT2
STSRLRTAPGMGDQS	RBM4	146	Q9BWF3
SPMDGRALRRSSHGS	ARHGEF17	1706	Q96PE2
MASAGSTARRAGSGS	ANKRD53	1	Q8N9V6
MSAGGSARKSTGRSS	DAB2IP	1	Q5VWQ8
RDMPAAGSLGSSSRN	FAT1	4466	Q14517
MSRRKPASGGLAASS	MSH3	1	P20585
MPRRKRNAGSSSDGT	KAT7	1	O95251
ASMFSPSSPRGGARR	KCTD8	71	Q6ZWB6
ERSMGSSREAARAPA	LRRC34	11	Q8IZ02
GSRSSLGARSMSDIR	GUCY2D	526	Q02846
DRGSCSARSPSGMLR	LINC-PINT	6	A0A455ZAR2
GSERADSSGARGMRL	KIF1C	251	O43896
GRDAASAARGSRMRP	LAGE3	46	Q14657
STSRLRTAPGMGDQS	RBM4B	146	Q9BQ04
SDDRMARPSGRSGHN	CSNK1G3	11	Q9Y6M4
QPSKRRRMGSGDSSR	PHF10	41	Q8WUB8
SRMPSLTASRAGSRA	CCDC166	356	P0CW27
RRMSSNRFPGSSGSN	MGARP	31	Q8TDB4
DPAARMSRSSGRSGS	KHDRBS1	6	Q07666
PSHSMRTRSGRLSSS	KMT2A	751	Q03164
NMSGLARRSPRSSDG	KCNE1	26	P15382
GRSSRDRTAPSAGMQ	CAMK2G	401	Q13555
SRDAGMRRTRSAPAA	nan	316	A6NNC1
ASRDAGMRRTRPGTS	nan	586	A6NNC1
SMGTGASSKSRPRTD	GPRASP1	446	Q5JY77
MGRSRSPATAKRGRS	SRRM2	481	Q9UQ35
TRRGRAPSSGDAKMA	TMEM80	36	Q96HE8
TPSPAMARRSRAAGT	PRR36	171	Q9H6K5
MSRRAPGSRLSSGGT	nan	1	Q6P435
RTASGGRTEQGMSRS	TAOK1	971	Q7L7X3
PSGSERRLSGDLSSM	MLXIPL	606	Q9NP71
RSSRPSMDSEGGSLL	PDLIM2	201	Q96JY6
MRSGAERRGSSAAAS	STK32C	1	Q86UX6
SDSDGQRRSMDAPSR	U2SURP	236	O15042
NASTMTRRGSSPGSL	RALGAPA1	851	Q6GYQ0
GGRARDPRMARAASS	SPEG	2096	Q15772
SRSGVSGGSRSLNMS	PHTF1	351	Q9UMS5
DNTERGMSRSSSPRG	YAF2	156	Q8IY57
GMSRSSSPRGEASSL	YAF2	161	Q8IY57
RRSRSETNPGSMEGT	ARHGAP9	246	Q9BRR9
RSMEGRPLGVSASSS	PLPP6	6	Q8IY26
FQRPGRRMSEGSSHS	PITPNM3	511	Q9BZ71
MSRPRKRLAGTSGSD	THYN1	1	Q9P016
AMGPRSCASAGRDSR	ZNF843	266	Q8N446
MASASSSQRGRSGSG	HNRNPA1	186	P09651
GARRSSMGPRSLDTC	ZNF619	41	Q8N2I2
GIMRRNSLSGSSTGS	WNK4	1211	Q96J92
SPSRSMLSCFRGGRA	ZBTB34	306	Q8NCN2
TPRIEASSMDGSGRR	LRP4	576	O75096