Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	RASGRP4 MAN1C1 CAPN1 CAPN3 GAS6 DYSF CELSR1 MICU3 PLA2G4C NRXN1 MEGF8 OTOF VCAN CHP2 ITSN2 NID1 SYT4 AGRN CDH11 PADI3 NIN	4.95e-07	749	158	21	GO:0005509
GeneOntologyMolecularFunction	hemoglobin beta binding	HBB HBD	6.22e-05	2	158	2	GO:0031722
GeneOntologyMolecularFunction	Hsp70 protein binding	DNAJB3 NOD2 DNAJA3 FICD DNAJB2	1.41e-04	63	158	5	GO:0030544
GeneOntologyMolecularFunction	oxygen carrier activity	IPCEF1 HBB HBD	1.66e-04	14	158	3	GO:0005344
GeneOntologyBiologicalProcess	glycerol ether metabolic process	FASN LIPE PLA2G4C GNPAT	2.83e-05	24	154	4	GO:0006662
GeneOntologyBiologicalProcess	ether lipid metabolic process	FASN LIPE PLA2G4C GNPAT	2.83e-05	24	154	4	GO:0046485
Domain	ASX_HYDROXYL	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1	1.50e-04	100	149	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1	2.06e-04	106	149	6	IPR000152
Domain	LAM_G_DOMAIN	GAS6 CELSR1 NRXN1 AGRN	2.33e-04	38	149	4	PS50025
Domain	G8_domain	PKHD1L1 CEMIP	3.75e-04	4	149	2	IPR019316
Domain	G8	PKHD1L1 CEMIP	3.75e-04	4	149	2	PS51484
Domain	G8	PKHD1L1 CEMIP	3.75e-04	4	149	2	SM01225
Domain	G8	PKHD1L1 CEMIP	3.75e-04	4	149	2	PF10162
Domain	LamG	GAS6 CELSR1 NRXN1 AGRN	4.12e-04	44	149	4	SM00282
Domain	EGF_CA	GAS6 CELSR1 MEGF8 VCAN NID1 AGRN	4.41e-04	122	149	6	SM00179
Domain	EGF-like_Ca-bd_dom	GAS6 CELSR1 MEGF8 VCAN NID1 AGRN	4.80e-04	124	149	6	IPR001881
Domain	EGF	GAS6 CELSR1 NRXN1 VCAN NID1 AGRN	5.23e-04	126	149	6	PF00008
Domain	EGF	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1 ASTN1 AGRN	6.06e-04	235	149	8	SM00181
Domain	EGF_3	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1 ASTN1 AGRN	6.06e-04	235	149	8	PS50026
Domain	FerI	DYSF OTOF	6.22e-04	5	149	2	SM01202
Domain	FerB	DYSF OTOF	6.22e-04	5	149	2	SM01201
Domain	Ferlin_B-domain	DYSF OTOF	6.22e-04	5	149	2	IPR012561
Domain	Ferlin_C	DYSF OTOF	6.22e-04	5	149	2	PF16165
Domain	Ferlin_C	DYSF OTOF	6.22e-04	5	149	2	IPR032362
Domain	-	ALDH1L1 FASN	6.22e-04	5	149	2	1.10.1200.10
Domain	FerIin_dom	DYSF OTOF	6.22e-04	5	149	2	IPR012968
Domain	FerI	DYSF OTOF	6.22e-04	5	149	2	PF08151
Domain	FerB	DYSF OTOF	6.22e-04	5	149	2	PF08150
Domain	PHOSPHOPANTETHEINE	ALDH1L1 FASN	6.22e-04	5	149	2	PS00012
Domain	Haemoglobin_b	HBB HBD	6.22e-04	5	149	2	IPR002337
Domain	PP-binding	ALDH1L1 FASN	6.22e-04	5	149	2	PF00550
Domain	ACP_DOMAIN	ALDH1L1 FASN	6.22e-04	5	149	2	PS50075
Domain	C2	CC2D1B DYSF C2CD4C OTOF ITSN2 SYT4	6.42e-04	131	149	6	PF00168
Domain	Cupredoxin	PKHD1L1 HEPHL1 PADI3	6.86e-04	22	149	3	IPR008972
Domain	C2	CC2D1B DYSF C2CD4C OTOF ITSN2 SYT4	8.13e-04	137	149	6	SM00239
Domain	EGF-like_dom	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1 ASTN1 AGRN	8.84e-04	249	149	8	IPR000742
Domain	BRK	CHD9 CHD8	9.29e-04	6	149	2	SM00592
Domain	BRK_domain	CHD9 CHD8	9.29e-04	6	149	2	IPR006576
Domain	BRK	CHD9 CHD8	9.29e-04	6	149	2	PF07533
Domain	PP-bd_ACP	ALDH1L1 FASN	9.29e-04	6	149	2	IPR009081
Domain	C2	CC2D1B DYSF C2CD4C OTOF ITSN2 SYT4	9.79e-04	142	149	6	PS50004
Domain	EGF_1	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1 ASTN1 AGRN	1.03e-03	255	149	8	PS00022
Domain	Laminin_G	GAS6 CELSR1 NRXN1 AGRN	1.18e-03	58	149	4	IPR001791
Domain	EGF-like_CS	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1 ASTN1 AGRN	1.20e-03	261	149	8	IPR013032
Domain	-	CC2D1B DYSF C2CD4C OTOF ITSN2 SYT4	1.21e-03	148	149	6	2.60.40.150
Domain	DnaJ_domain_CS	DNAJB3 DNAJA3 DNAJB2	1.26e-03	27	149	3	IPR018253
Domain	EGF_2	GAS6 CELSR1 NRXN1 MEGF8 VCAN NID1 ASTN1 AGRN	1.32e-03	265	149	8	PS01186
Domain	DHC_N1	DNAH10 DNAH5	1.72e-03	8	149	2	PF08385
Domain	Pectin_lyase_fold/virulence	PKHD1L1 CEMIP	1.72e-03	8	149	2	IPR011050
Domain	Dynein_heavy_dom-1	DNAH10 DNAH5	1.72e-03	8	149	2	IPR013594
Domain	EGF_LAM_2	CELSR1 MEGF8 AGRN	1.73e-03	30	149	3	PS50027
Domain	EGF_LAM_1	CELSR1 MEGF8 AGRN	1.73e-03	30	149	3	PS01248
Domain	C2_dom	CC2D1B DYSF C2CD4C OTOF ITSN2 SYT4	2.04e-03	164	149	6	IPR000008
Domain	MYTH4	ARHGAP39 MYO15B	2.19e-03	9	149	2	PS51016
Domain	MyTH4	ARHGAP39 MYO15B	2.19e-03	9	149	2	SM00139
Domain	MyTH4_dom	ARHGAP39 MYO15B	2.19e-03	9	149	2	IPR000857
Domain	MyTH4	ARHGAP39 MYO15B	2.19e-03	9	149	2	PF00784
Domain	EF-hand_8	CAPN1 CAPN3 MICU3	2.48e-03	34	149	3	PF13833
Domain	EF_HAND_2	RASGRP4 CAPN1 CAPN3 MICU3 CHP2 ITSN2 NIN	2.57e-03	231	149	7	PS50222
Domain	EF_hand_dom	RASGRP4 CAPN1 CAPN3 MICU3 CHP2 ITSN2 NIN	2.63e-03	232	149	7	IPR002048
Domain	EGF_Lam	CELSR1 MEGF8 AGRN	2.70e-03	35	149	3	SM00180
Domain	Laminin_EGF	CELSR1 MEGF8 AGRN	2.70e-03	35	149	3	PF00053
Domain	P-loop_NTPase	CPLANE2 PNKP DNAH10 WRN PEX1 GAL3ST4 CHD9 CHD8 ZNFX1 ABCA7 NOD2 MYO15B SBNO1 YLPM1 DNAH5	3.23e-03	848	149	15	IPR027417
Domain	Hist_deacetyl	HDAC7 HDAC10	3.32e-03	11	149	2	PF00850
Domain	-	HDAC7 HDAC10	3.32e-03	11	149	2	3.40.800.20
Domain	His_deacetylse_dom	HDAC7 HDAC10	3.32e-03	11	149	2	IPR023801
Domain	Laminin_G_1	GAS6 AGRN	3.32e-03	11	149	2	PF00054
Domain	His_deacetylse	HDAC7 HDAC10	3.32e-03	11	149	2	IPR000286
Domain	Laminin_EGF	CELSR1 MEGF8 AGRN	3.42e-03	38	149	3	IPR002049
Domain	EGF_dom	MEGF8 NID1	3.96e-03	12	149	2	IPR024731
Domain	calpain_III	CAPN1 CAPN3	3.96e-03	12	149	2	SM00720
Domain	C2_III	CAPN1 CAPN3	3.96e-03	12	149	2	IPR033883
Domain	Globin	HBB HBD	3.96e-03	12	149	2	IPR000971
Domain	UBX	UBXN6 ASPSCR1	3.96e-03	12	149	2	SM00166
Domain	EGF_3	MEGF8 NID1	3.96e-03	12	149	2	PF12947
Domain	Calpain_III	CAPN1 CAPN3	3.96e-03	12	149	2	IPR022683
Domain	Globin	HBB HBD	3.96e-03	12	149	2	PF00042
Domain	GLOBIN	HBB HBD	3.96e-03	12	149	2	PS01033
Domain	Laminin_G_2	GAS6 CELSR1 NRXN1	3.96e-03	40	149	3	PF02210
Domain	UBX_dom	UBXN6 ASPSCR1	4.65e-03	13	149	2	IPR001012
Domain	Calpain_III	CAPN1 CAPN3	4.65e-03	13	149	2	PF01067
Domain	Calpain_domain_III	CAPN1 CAPN3	4.65e-03	13	149	2	IPR022682
Domain	UBX	UBXN6 ASPSCR1	4.65e-03	13	149	2	PF00789
Domain	UBX	UBXN6 ASPSCR1	4.65e-03	13	149	2	PS50033
Domain	-	HBB HBD	4.65e-03	13	149	2	1.10.490.10
Domain	Globin/Proto	HBB HBD	4.65e-03	13	149	2	IPR012292
Domain	-	PHF24 CAPN1 CAPN3 MICU3 CHP2 ITSN2 NIN	5.02e-03	261	149	7	1.10.238.10
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH5	5.40e-03	14	149	2	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH5	5.40e-03	14	149	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH5	5.40e-03	14	149	2	IPR013602
Domain	DHC_N2	DNAH10 DNAH5	5.40e-03	14	149	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH10 DNAH5	5.40e-03	14	149	2	IPR011704
Domain	Calpain_cysteine_protease	CAPN1 CAPN3	5.40e-03	14	149	2	IPR022684
Domain	MT	DNAH10 DNAH5	5.40e-03	14	149	2	PF12777
Domain	AAA_8	DNAH10 DNAH5	5.40e-03	14	149	2	PF12780
Domain	AAA_5	DNAH10 DNAH5	5.40e-03	14	149	2	PF07728
Domain	ARM-type_fold	COPB1 ZNFX1 TRIP12 NCDN INF2 ARMC5 MMS19 GPRASP2	5.92e-03	339	149	8	IPR016024
Domain	DHC_fam	DNAH10 DNAH5	6.20e-03	15	149	2	IPR026983
Domain	Peptidase_C2	CAPN1 CAPN3	6.20e-03	15	149	2	PF00648
Domain	Dynein_heavy	DNAH10 DNAH5	6.20e-03	15	149	2	PF03028
Domain	CysPc	CAPN1 CAPN3	6.20e-03	15	149	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN1 CAPN3	6.20e-03	15	149	2	IPR001300
Domain	Dynein_heavy_dom	DNAH10 DNAH5	6.20e-03	15	149	2	IPR004273
Domain	CALPAIN_CAT	CAPN1 CAPN3	6.20e-03	15	149	2	PS50203
Domain	DnaJ	DNAJB3 DNAJA3 DNAJB2	6.62e-03	48	149	3	PF00226
Domain	-	CPLANE2 PNKP DNAH10 WRN PEX1 CHD9 CHD8 ZNFX1 ABCA7 NOD2 SBNO1 YLPM1 DNAH5	6.81e-03	746	149	13	3.40.50.300
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RHBDF2 POLE CHD8 DYSF ABCA7 HDAC7 MAPK8IP3 NOD2 FASN CELSR1 SIRT2 ARAP3 MEGF8 INF2 ZNF592 CDK13 BTBD7 USP40 XXYLT1 EHMT1 AGRN	3.38e-08	1105	158	21	35748872
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TBRG4 COPB1 IARS1 POLE DAD1 PEX1 TRIP12 NCDN RNF170 FASN PDE12 INF2 FDFT1 XXYLT1 MMS19 DNAJB2 GPRASP2	1.52e-06	942	158	17	31073040
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TUT4 RHBDF2 MAN1C1 CAPN1 GAS6 CHD9 ARHGAP39 NCDN MAPK8IP3 BPTF INF2 CDK13 KCNJ3 USP40 XXYLT1 EHMT1 RPRD2 ASPSCR1 TET3 VAV2 GULP1	4.25e-06	1489	158	21	28611215
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	COL6A3 NID1 AGRN	5.07e-06	8	158	3	12766770
Pubmed	The functional interactome landscape of the human histone deacetylase family.	COPB1 BEND3 HDAC7 DNAJA3 ZNF592 FDFT1 YLPM1 HDAC10 DNAJB2	7.60e-06	289	158	9	23752268
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	RRP1B IARS1 CAPN1 PEX1 AURKA MYO15B PRICKLE3 ARMC5 ASPSCR1 LAS1L HBB HBD AGRN	7.83e-06	639	158	13	23443559
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CC2D1B FNDC1 MYO15B CDK13 EHMT1 UNC80	9.89e-06	107	158	6	11347906
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TBRG4 COPB1 NCDN DNAJA3 PDE12 FDFT1 EHMT1 MMS19 EXOC1 LAS1L CDCA7L GNPAT	1.06e-05	560	158	12	35241646
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL6A3 COL6A5 VCAN NID1 AGRN	1.12e-05	64	158	5	22261194
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	PNKP SRBD1 DNAJA3 BPTF ZNF592 EHMT1 LAS1L	1.75e-05	177	158	7	26206133
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	RASGRP4 TRIP12 LIPE POLI RPRD2 MMS19 EXOC1 HDAC10 CDH11	1.79e-05	322	158	9	26514267
Pubmed	Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.	PDGFRB CCM2 VCAN	1.96e-05	12	158	3	32648916
Pubmed	Variation within DNA repair pathway genes and risk of multiple sclerosis.	PNKP ERCC5 POLE WRN MMS19	1.99e-05	72	158	5	20522537
Pubmed	Involvement of calpains in Ca2+-induced disruption of excitation-contraction coupling in mammalian skeletal muscle fibers.	CAPN1 CAPN3	2.05e-05	2	158	2	19295178
Pubmed	Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.	HBB HBD	2.05e-05	2	158	2	37902616
Pubmed	Identification and structural basis for a novel interaction between Vav2 and Arap3.	ARAP3 VAV2	2.05e-05	2	158	2	22750419
Pubmed	Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.	HBB HBD	2.05e-05	2	158	2	270684
Pubmed	Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.	HBB HBD	2.05e-05	2	158	2	21099112
Pubmed	A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.	HBB HBD	2.05e-05	2	158	2	11121056
Pubmed	mu-Calpain and calpain-3 are not autolyzed with exhaustive exercise in humans.	CAPN1 CAPN3	2.05e-05	2	158	2	16107503
Pubmed	Decreased hepcidin mRNA expression in thalassemic mice.	HBB HBD	2.05e-05	2	158	2	14675418
Pubmed	Nucleotide sequences of the mouse globin beta gene cDNAs in a wild derived new haplotype Hbb(w1).	HBB HBD	2.05e-05	2	158	2	10441738
Pubmed	Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche.	HBB HBD	2.05e-05	2	158	2	32344432
Pubmed	Responses of primary osteoblasts and osteoclasts from hemizygous β-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D3.	HBB HBD	2.05e-05	2	158	2	31562377
Pubmed	Effects of human gamma-globin in murine beta-thalassaemia.	HBB HBD	2.05e-05	2	158	2	16803575
Pubmed	The adult beta-globin genes of the "single" type mouse C57BL.	HBB HBD	2.05e-05	2	158	2	7237554
Pubmed	Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption.	HBB HBD	2.05e-05	2	158	2	27245334
Pubmed	Co-inheritance of alpha- and beta-thalassaemia in mice ameliorates thalassaemic phenotype.	HBB HBD	2.05e-05	2	158	2	17493845
Pubmed	An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression.	HBB HBD	2.05e-05	2	158	2	28641125
Pubmed	A mouse model for beta 0-thalassemia.	HBB HBD	2.05e-05	2	158	2	8524813
Pubmed	Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.	HBB HBD	2.05e-05	2	158	2	25616571
Pubmed	Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain.	HBB HBD	2.05e-05	2	158	2	23074246
Pubmed	High phosphate intake induces bone loss in nephrectomized thalassemic mice.	HBB HBD	2.05e-05	2	158	2	35622784
Pubmed	A humanized mouse model for a common beta0-thalassemia mutation.	HBB HBD	2.05e-05	2	158	2	15780748
Pubmed	Evolution of the mouse beta-globin genes: a recent gene conversion in the Hbbs haplotype.	HBB HBD	2.05e-05	2	158	2	3870864
Pubmed	Molecular characterization of (deltabeta)(0)/beta(0)-thalassemia and (deltabeta)(0)-thalassemia/hemoglobin E in Thai patients.	HBB HBD	2.05e-05	2	158	2	11860449
Pubmed	Protein studies in dysferlinopathy patients using llama-derived antibody fragments selected by phage display.	CAPN3 DYSF	2.05e-05	2	158	2	15827562
Pubmed	Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.	HBB HBD	2.05e-05	2	158	2	12127975
Pubmed	The chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.	HBB HBD	2.05e-05	2	158	2	24817273
Pubmed	Ligation-mediated amplification of RNA from murine erythroid cells reveals a novel class of beta globin mRNA with an extended 5'-untranslated region.	HBB HBD	2.05e-05	2	158	2	8041612
Pubmed	A 66-base pair insert bridges the deletion responsible for a mouse model of beta-thalassemia.	HBB HBD	2.05e-05	2	158	2	3017971
Pubmed	Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.	HBB HBD	2.05e-05	2	158	2	273235
Pubmed	Mild-intensity physical activity prevents cardiac and osseous iron deposition without affecting bone mechanical property or porosity in thalassemic mice.	HBB HBD	2.05e-05	2	158	2	35396390
Pubmed	Molecular characterization of a novel homozygous deletion in β-globin cluster causing (δβ)0-Thalassemia among Tunisian family.	HBB HBD	2.05e-05	2	158	2	36214153
Pubmed	The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.	HBB HBD	2.05e-05	2	158	2	728996
Pubmed	CNTO 530 increases expression of HbA and HbF in murine models of β-thalassemia and sickle cell anemia.	HBB HBD	2.05e-05	2	158	2	23157711
Pubmed	HbA2-Partinico or delta(A2)Pro-->Thr, a new genetic variation in the delta-globin gene in cis to the beta(+) thal IVS-I-110 G>A, and the heterogeneity of delta-globin alleles in double heterozygotes for beta- and delta-globin gene defects.	HBB HBD	2.05e-05	2	158	2	19609526
Pubmed	Discovery of a new HBB haplotype w2 in a wild-derived house mouse, Mus musculus.	HBB HBD	2.05e-05	2	158	2	18299925
Pubmed	Transposition of a long member of the L1 major interspersed DNA family into the mouse beta globin gene locus.	HBB HBD	2.05e-05	2	158	2	2991851
Pubmed	A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.	HBB HBD	2.05e-05	2	158	2	6086313
Pubmed	Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain.	HBB HBD	2.05e-05	2	158	2	22203977
Pubmed	A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia.	HBB HBD	2.05e-05	2	158	2	16631345
Pubmed	A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.	HBB HBD	2.05e-05	2	158	2	12480689
Pubmed	Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence.	HBB HBD	2.05e-05	2	158	2	482942
Pubmed	Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.	HBB HBD	2.05e-05	2	158	2	11830454
Pubmed	Second generation knockout sickle mice: the effect of HbF.	HBB HBD	2.05e-05	2	158	2	11154217
Pubmed	The complete nucleotide sequence of a beta-globin-like structure, beta h2, from the [Hbb]d mouse BALB/c.	HBB HBD	2.05e-05	2	158	2	6736028
Pubmed	Running exercise alleviates trabecular bone loss and osteopenia in hemizygous β-globin knockout thalassemic mice.	HBB HBD	2.05e-05	2	158	2	24780610
Pubmed	First report on the co-inheritance of beta-globin IVS-I-5 (G-->C) thalassemia with delta globin CD12 {Asn-->Lys (AAT-->AAA)}HbA₂-NYU in Iran.	HBB HBD	2.05e-05	2	158	2	21194254
Pubmed	Significance of borderline hemoglobin A2 values in an Italian population with a high prevalence of beta-thalassemia.	HBB HBD	2.05e-05	2	158	2	18603555
Pubmed	Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns.	HBB HBD	2.05e-05	2	158	2	264241
Pubmed	Lack of neighborhood effects from a transcriptionally active phosphoglycerate kinase-neo cassette located between the murine beta-major and beta-minor globin genes.	HBB HBD	2.05e-05	2	158	2	11418464
Pubmed	Highly conserved structure in the promoter region of the gene for muscle-specific calpain, p94.	CAPN1 CAPN3	2.05e-05	2	158	2	8997499
Pubmed	Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S.	HBB HBD	2.05e-05	2	158	2	21304105
Pubmed	In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.	HBB HBD	2.05e-05	2	158	2	30422819
Pubmed	β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications.	HBB HBD	2.05e-05	2	158	2	24297746
Pubmed	Single nucleotide polymorphisms in the NER pathway and clinical outcome of patients with bone malignant tumors.	ERCC5 MMS19	2.05e-05	2	158	2	23679317
Pubmed	Cloning and amplification of alpha and beta mouse globin gene sequences synthesised in vitro.	HBB HBD	2.05e-05	2	158	2	338418
Pubmed	Nephrectomy Does not Exacerbate Cancellous Bone loss in Thalassemic Mice.	HBB HBD	2.05e-05	2	158	2	32385316
Pubmed	The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.	HBB HBD	2.05e-05	2	158	2	519759
Pubmed	Humanized beta-thalassemia mouse model containing the common IVSI-110 splicing mutation.	HBB HBD	2.05e-05	2	158	2	16421096
Pubmed	Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.	HBB HBD	2.05e-05	2	158	2	7935410
Pubmed	Successful treatment of murine beta-thalassemia intermedia by transfer of the human beta-globin gene.	HBB HBD	2.05e-05	2	158	2	11877258
Pubmed	Tracking of mouse cell lineage using microinjected DNA sequences: analyses using genomic Southern blotting and tissue-section in situ hybridizations.	HBB HBD	2.05e-05	2	158	2	3428512
Pubmed	The molecular characterization of an A:T to G:C transition in the Hbb-b1 gene of the murine homologue of hemoglobin Rainier.	HBB HBD	2.05e-05	2	158	2	1820025
Pubmed	Super-resolution imaging reveals three-dimensional folding dynamics of the β-globin locus upon gene activation.	HBB HBD	2.05e-05	2	158	2	22767512
Pubmed	Transgene copy number-dependent rescue of murine beta-globin knockout mice carrying a 183 kb human beta-globin BAC genomic fragment.	HBB HBD	2.05e-05	2	158	2	15820143
Pubmed	The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50.	HBB HBD	2.05e-05	2	158	2	3620470
Pubmed	The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.	HBB HBD	2.05e-05	2	158	2	569555
Pubmed	The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome.	ERCC5 WRN	2.05e-05	2	158	2	21558802
Pubmed	The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model.	HBB HBD	2.05e-05	2	158	2	33822774
Pubmed	Evaluation of Stem Cell-Derived Red Blood Cells as a Transfusion Product Using a Novel Animal Model.	HBB HBD	2.05e-05	2	158	2	27959920
Pubmed	Mouse haemoglobin beta chains. Comparative sequence data on adult major and minor beta chains from two species, Mus musculus and Mus cervicolor.	HBB HBD	2.05e-05	2	158	2	999642
Pubmed	Predictive impact of common variations in DNA repair genes on clinical outcome of osteosarcoma.	ERCC5 MMS19	2.05e-05	2	158	2	23886164
Pubmed	Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia.	HBB HBD	2.05e-05	2	158	2	22427201
Pubmed	Heparanase Level and Procoagulant Activity Are Increased in Thalassemia and Attenuated by Janus Kinase 2 Inhibition.	HBB HBD	2.05e-05	2	158	2	32745462
Pubmed	Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells.	HBB HBD	2.05e-05	2	158	2	14615383
Pubmed	Hemoglobin induction in mouse macrophages.	HBB HBD	2.05e-05	2	158	2	10359765
Pubmed	Evolution of duplicated beta-globin genes and the structural basis of hemoglobin isoform differentiation in Mus.	HBB HBD	2.05e-05	2	158	2	19675095
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	DYNC2I2 CPE ARHGAP39 NCDN DNAJA3 MICU3 VCAN HBB HBD GULP1	2.96e-05	430	158	10	32581705
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	COL6A3 MAN1C1 CAPN1 GAS6 C1RL CPE ALDH1L1 DYSF FASN MEGF8 NID1 C5 HBB AGRN CDH11 SOD3	3.20e-05	1070	158	16	23533145
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	PNKP COPB1 RRP1B CAPN1 CHD9 CHD8 TRIP12 BPTF ZNF592 LAS1L HBB	3.51e-05	533	158	11	30554943
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	ERCC5 PDGFRB WRN DAD1 ALDH1L1 NOD2 AURKA POLI EHMT1	3.52e-05	351	158	9	20453000
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBXN6 DYSF HDAC7 ARMC5 LAS1L	4.44e-05	85	158	5	15449545
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	POLE PEX1 CC2D1B CHD8 ZNFX1 NCDN CEMIP ARAP3 CDK13 ARMC5 AGRN GNPAT	4.54e-05	650	158	12	38777146
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ELOB POLE BEND3 CHD8 TRIP12 BPTF ZNF592 CDK13 EHMT1 CDCA7L	6.12e-05	469	158	10	27634302
Pubmed	An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis.	HBB HBD	6.13e-05	3	158	2	17607360
Pubmed	Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.	HBB HBD	6.13e-05	3	158	2	28151426
Pubmed	Oxygen affinity of hemoglobin regulates O2 consumption, metabolism, and physical activity.	HBB HBD	6.13e-05	3	158	2	12458204
Pubmed	In vivo blood flow abnormalities in the transgenic knockout sickle cell mouse.	HBB HBD	6.13e-05	3	158	2	10079113
GeneFamily	EF-hand domain containing	RASGRP4 CAPN1 CAPN3 MICU3 CHP2 ITSN2 NIN	3.25e-04	219	107	7	863
GeneFamily	Ferlin family	DYSF OTOF	5.12e-04	6	107	2	828
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CC2D1B C2CD4C ITSN2	1.25e-03	36	107	3	823
GeneFamily	Hemoglobin subunits	HBB HBD	1.51e-03	10	107	2	940
GeneFamily	HAD Asp-based non-protein phosphatases	PNKP PHOSPHO1	1.84e-03	11	107	2	1045
GeneFamily	UBX domain containing	UBXN6 ASPSCR1	2.59e-03	13	107	2	364
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	DNAJB3 DNAJA3 DNAJB2	3.05e-03	49	107	3	584
GeneFamily	C2 domain containing\|Calpains	CAPN1 CAPN3	3.46e-03	15	107	2	975
GeneFamily	Dyneins, axonemal	DNAH10 DNAH5	4.45e-03	17	107	2	536
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	C1RL CR1L VCAN	4.68e-03	57	107	3	1179
Coexpression	GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN	POLE MYO1H MAP3K14 ZNFX1 AURKA LIPE MEGF8 AGRN SLC35A5	3.50e-06	200	157	9	M7162
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN	MICU3 MEGF8 CDK13 BTBD7 NKPD1 TRPV6 RPRD2 VAV2	4.98e-06	157	157	8	M7733
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 USP43 CR1L CLCNKB KCNJ3 IPCEF1 FYB2 TMEM117	1.46e-07	164	160	8	d847d509bb1791638032ade6755d8164586b5bd5
ToppCell	PBMC-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	d685a5a2e525db2eba449cfa1e5cd54eb36162a8
ToppCell	PBMC-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	5d8d6fd7800f76ee3aa5cef95241d8e6d7e8db04
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	100b5afdf3c6ab07ffc493f7883f5a7b31c59184
ToppCell	COVID-19_Severe-Hematopoietic_R\|COVID-19_Severe / Disease group, lineage and cell class	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	30f064ab7c3890e6f419a845276b145112e78f52
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	f3b1907c3b6f930bc161f46efce5e143babab507
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	44ce50cb99df8ffc50eba311adcf688477618659
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	17542ccd52a821c9e99b1a7469e80502e764b3fd
ToppCell	COVID-19_Severe-Hematopoietic_R-RBC\|COVID-19_Severe / Disease group, lineage and cell class	ELOB ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.68e-07	185	160	8	3ed6090b822c6d1d400a421236cddc7511743932
ToppCell	IIF-Other-RBC\|IIF / Disease, Lineage and Cell Type	ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB DNAJB2	3.83e-07	186	160	8	db3c3fc2045c657b300b640bf228640c30782509
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	COL6A3 PDGFRB CPE EXTL1 FNDC1 HBB CDH11 SOD3	4.15e-07	188	160	8	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	3'-Distal_airway-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 CCDC146 CCDC190 GPR162 CELSR1 CFAP52 DNAH5 FYB2	5.48e-07	195	160	8	72fa2ba064055e2fee2b2cb8633c8f9a3c4373da
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL6A3 PDGFRB COL6A5 FNDC1 VCAN NID1 CDH11 SOD3	6.39e-07	199	160	8	6a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial\|2m / Sample Type, Dataset, Time_group, and Cell type.	COL6A3 CPA5 PDGFRB FDCSP FNDC1 VCAN NID1 CDH11	6.63e-07	200	160	8	3da9441c0f1e242f0d195de47ecd4c24dfdca232
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial-Proteoglycan-expressing_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	COL6A3 CPA5 PDGFRB FDCSP FNDC1 VCAN NID1 CDH11	6.63e-07	200	160	8	eed2bafddcd041ef5fcc4d1d31edb8be4d83ce01
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HBD CR1L PHOSPHO1 NRXN1 KEL HBB CDH11	1.01e-06	146	160	7	03a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 TECTB COL6A5 PKHD1L1 ASTN1 HEPHL1 UNC80	1.86e-06	160	160	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 TECTB COL6A5 PKHD1L1 ASTN1 HEPHL1 UNC80	1.86e-06	160	160	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BICDL2 CCDC146 TECTB CELSR1 CHP2 FYB2 PADI3	1.94e-06	161	160	7	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 USP43 CR1L KCNJ3 IPCEF1 FYB2 TMEM117	2.38e-06	166	160	7	6fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS6 C1RL CPE EXTL1 PKHD1L1 BICDL1 TMEM117	2.48e-06	167	160	7	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS6 C1RL CPE EXTL1 PKHD1L1 BICDL1 TMEM117	2.48e-06	167	160	7	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 CCDC146 USP43 ARHGAP39 GPR162 CFAP52 DNAH5	3.13e-06	173	160	7	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	Healthy-RBC\|World / disease group, cell group and cell class	ACHE HBD CR1L PHOSPHO1 VCAN KEL HBB	3.64e-06	177	160	7	2ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell	Healthy-RBC\|Healthy / disease group, cell group and cell class	ACHE HBD CR1L AURKA PHOSPHO1 KEL HBB	3.64e-06	177	160	7	945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1C1 COL6A5 CPE NRXN1 GPRASP2 TPH1 NIN	3.78e-06	178	160	7	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	COVID-19_Moderate-RBC\|World / disease group, cell group and cell class	ACHE UBXN6 HBD CR1L PHOSPHO1 HBB DNAJB2	3.92e-06	179	160	7	932fa98c0981ef8ef1e4945cdd4ae8c6c0858251
ToppCell	Multiple_Sclerosis-Other-RBC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	3.92e-06	179	160	7	15763dc59ee6186416e203ffbb450ae4608eba59
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDGFRB COL6A5 FNDC1 VCAN NID1 CDH11	4.22e-06	181	160	7	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDGFRB COL6A5 FNDC1 VCAN NID1 CDH11	4.22e-06	181	160	7	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPE PKHD1L1 CELSR1 SYT4 AGRN CDH11 GPRASP2	4.53e-06	183	160	7	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	COVID-19_Moderate-RBC\|COVID-19_Moderate / disease group, cell group and cell class	ACHE UBXN6 HBD CR1L PHOSPHO1 HBB DNAJB2	4.53e-06	183	160	7	0dc337cd3f4f7964b0a268139c7ddc0f58b6a279
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 PDGFRB CPE EXTL1 FDCSP NID1 CDH11	4.53e-06	183	160	7	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 PDGFRB CPE EXTL1 FDCSP NID1 CDH11	4.53e-06	183	160	7	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 PDGFRB CPE EXTL1 FDCSP NID1 CDH11	4.53e-06	183	160	7	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	COVID-19_Severe-RBC\|COVID-19_Severe / disease group, cell group and cell class	ACHE UBXN6 HBD CR1L PHOSPHO1 HBB DNAJB2	4.70e-06	184	160	7	bb58244194ffb5558fbe85c5f856888210dcb1e8
ToppCell	COVID-19_Severe-RBC\|World / disease group, cell group and cell class	ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	4.87e-06	185	160	7	96b7058b1b282134970aa9e75285760a9f94a8b5
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PHF24 DUSP6 VCAN ASTN1 HDAC10 TET3 CDH11	5.04e-06	186	160	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HBD CR1L PKHD1L1 PHOSPHO1 KEL HBB SOD3	5.04e-06	186	160	7	6078aa16261554c7fd41137b8de1362d15b30490
ToppCell	15-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	HBD ALDH1L1 CR1L PHOSPHO1 KEL HBB GLTPD2	5.41e-06	188	160	7	c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell	15-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	HBD ALDH1L1 CR1L PHOSPHO1 KEL HBB GLTPD2	5.41e-06	188	160	7	2534684e4932c1255c24a26ca2277ac7af0a118b
ToppCell	facs-Pancreas-Endocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSRR CPE MICU3 NRXN1 SYT4 ASTN1 UNC80	5.60e-06	189	160	7	010fdd70e9d0e21b856306a29ff877776a480319
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH10 CCDC146 CFAP52 DNAH5 CDCA7L FYB2 IQCK	5.60e-06	189	160	7	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	severe_COVID-19-RBC\|severe_COVID-19 / disease group, cell group and cell class (v2)	ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	5.80e-06	190	160	7	3a5723c2daf58c1932edd70910db4b8b30f63f42
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSRR CPE MICU3 NRXN1 SYT4 ASTN1 UNC80	6.00e-06	191	160	7	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSRR CPE MICU3 NRXN1 SYT4 ASTN1 UNC80	6.00e-06	191	160	7	a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell	severe_COVID-19-RBC\|World / disease group, cell group and cell class (v2)	ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	6.21e-06	192	160	7	1b4e28fd2e3d70ab48dbe96b280d35395889fbe2
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDGFRB COL6A5 NID1 CDH11 SOD3 GULP1	6.21e-06	192	160	7	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	Influenza_Severe-RBC\|Influenza_Severe / Disease group and Cell class	ACHE UBXN6 HBD CR1L PHOSPHO1 KEL HBB	6.21e-06	192	160	7	f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDGFRB CEMIP FNDC1 VCAN NID1 CDH11	6.43e-06	193	160	7	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 PDGFRB FNDC1 VCAN NID1 CDH11 SOD3	6.43e-06	193	160	7	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDGFRB CEMIP FNDC1 VCAN NID1 CDH11	6.43e-06	193	160	7	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH10 CCDC146 CCDC190 CELSR1 CFAP52 DNAH5 FYB2	6.65e-06	194	160	7	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	3'-Distal_airway\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 CCDC146 CCDC190 GPR162 CFAP52 DNAH5 FYB2	6.65e-06	194	160	7	e9ff4398e880d13894e52c0ba9cf19a7662c248b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDGFRB CPE FNDC1 VCAN NID1 CDH11	6.65e-06	194	160	7	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 PDGFRB COL6A5 CPE VCAN CDH11 SOD3	6.87e-06	195	160	7	51db90e7611f7d69980878c046505ff34212079b
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL6A3 PDGFRB CPE FNDC1 VCAN NID1 CDH11	7.11e-06	196	160	7	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 DNAH10 GAS6 COL6A5 NID1 DNAH5 SOD3	7.11e-06	196	160	7	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	15-Trachea-RBC-RBC\|Trachea / Age, Tissue, Lineage and Cell class	ACHE GATA5 CR1L AURKA PHOSPHO1 KEL HBB	7.11e-06	196	160	7	511bfc06c34d5add2ae561cca463d1e4e2d43e20
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 DNAH10 GAS6 COL6A5 NID1 DNAH5 SOD3	7.11e-06	196	160	7	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 COL6A5 FNDC1 VCAN NID1 CDH11 SOD3	7.11e-06	196	160	7	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	15-Trachea-RBC\|Trachea / Age, Tissue, Lineage and Cell class	ACHE GATA5 CR1L AURKA PHOSPHO1 KEL HBB	7.11e-06	196	160	7	bf2670e5ae996a19987bc70aa5a37d133db789eb
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	COL6A3 CHD9 COL6A5 PLA2G4C VCAN CDH11 GULP1	7.35e-06	197	160	7	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 PDGFRB GAS6 FNDC1 VCAN MOCS1 CDH11	7.35e-06	197	160	7	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 PDGFRB GAS6 FNDC1 VCAN MOCS1 CDH11	7.35e-06	197	160	7	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	COVID-19-COVID-19_Mild-Others-RBC\|COVID-19_Mild / Disease, condition lineage and cell class	UBXN6 HBD CR1L PHOSPHO1 HBB DNAJB2 MOCS1	7.35e-06	197	160	7	3bae601e5d9689ea57e923814af8cdcae690becc
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB ACHE GAS6 CPE FDCSP ASTN1 SOD3	7.35e-06	197	160	7	5fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 PDGFRB GAS6 FNDC1 VCAN MOCS1 CDH11	7.35e-06	197	160	7	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDGFRB CEMIP FNDC1 VCAN NID1 CDH11	7.35e-06	197	160	7	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	10x5'v1-week_12-13-Hematopoietic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ACHE GATA5 CR1L PHOSPHO1 KEL HBB HBD	7.59e-06	198	160	7	d02e1ff7f68dedaca1e367c7cade772e7b355f45
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	COL6A3 PDGFRB C1RL FNDC1 VCAN CDH11 SOD3	7.59e-06	198	160	7	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	distal-1-mesenchymal-Mesothelial\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FDCSP ALDH1L1 BICDL1 FNDC1 SYT4 ASTN1 CDH11	7.85e-06	199	160	7	8dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL6A3 PDGFRB COL6A5 FNDC1 VCAN NID1 CDH11	7.85e-06	199	160	7	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	ILEUM-inflamed-(8)_Fibroblast\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL6A3 PDGFRB FNDC1 VCAN NID1 CDH11 SOD3	7.85e-06	199	160	7	cb3c04b91c8e8080137823b11c76ca0a2adda52d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PDGFRB COL6A5 FNDC1 VCAN NID1 CDH11	7.85e-06	199	160	7	6139687a3a5025cb98da4dba0183f95fcae3dc61
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 PDGFRB COL6A5 CPE NID1 CDH11 SOD3	7.85e-06	199	160	7	fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PDGFRB FNDC1 VCAN NID1 CDH11 SOD3	7.85e-06	199	160	7	a843bdfcb58bec5e2a94a5ec9d5b8c5e4aef15d2
ToppCell	Lung_Parenchyma-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 ACHE HBD CR1L PHOSPHO1 KEL HBB	8.11e-06	200	160	7	b5f2892bc45fda5ae05e269b840305a608a07c37
ToppCell	Lung_Parenchyma-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 ACHE HBD CR1L PHOSPHO1 KEL HBB	8.11e-06	200	160	7	9ce1f91991637fc3af0f6a80a85e1a44276fe412
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 COL6A5 FNDC1 VCAN NID1 CDH11 SOD3	8.11e-06	200	160	7	c5d818203bef80ff97c2e0158cf61970673dd258
ToppCell	Lung_Parenchyma-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 ACHE HBD CR1L PHOSPHO1 KEL HBB	8.11e-06	200	160	7	fdf3e60cf94f398a56c0fa72813d0459f5ce081b
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-4\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL6A3 PDGFRB COL6A5 FNDC1 NID1 CDH11 SOD3	8.11e-06	200	160	7	54b18c92daaa3b3368c0c46134b0c27e10c8dbb0
ToppCell	wk_15-18-Mesenchymal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL6A3 PDGFRB GATA5 VCAN NID1 CDH11 SOD3	8.11e-06	200	160	7	4d484260ecbbbd9f820b445bdcc2666f6c464b73
ToppCell	Lung_Parenchyma-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A3 ACHE HBD CR1L PHOSPHO1 KEL HBB	8.11e-06	200	160	7	199165be1aef8497af71b74690a11de18fbe073c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PDGFRB FNDC1 VCAN NID1 CDH11 SOD3	8.11e-06	200	160	7	0655328373d1b58828e141ddb0dcbb2cce10dc50
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL6A3 PDGFRB COL6A5 CPE HBB CDH11 SOD3	8.11e-06	200	160	7	16a3685c41194a0a4a772e4eee372160263480e0
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 PDGFRB CPE COCH NID1 MOCS1 SOD3	8.11e-06	200	160	7	fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCell	Parenchyma_COVID-19-Stromal-TX-Erythrocytes\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL6A3 ACHE HBD CR1L PHOSPHO1 KEL HBB	8.11e-06	200	160	7	a9edac2f5e009662df452ec032a80e855cdac28f
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCDN FICD KCNJ3 CHP2 KEL C5	9.88e-06	136	160	6	a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|356C / Donor, Lineage, Cell class and subclass (all cells)	CPLANE2 ACHE MYO1H HBD CR1L HBB	1.73e-05	150	160	6	6bdf9df586f348641a25a445e83a41e47e7f347e
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CPLANE2 ACHE MYO1H HBD CR1L HBB	2.57e-05	161	160	6	8ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCell	11.5-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	ACHE HBD CR1L PHOSPHO1 KEL HBB	2.76e-05	163	160	6	e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell	11.5-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	ACHE HBD CR1L PHOSPHO1 KEL HBB	2.76e-05	163	160	6	31b60e065bac4ad380247964e7574f210106ebae
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPLANE2 BICDL2 DNAH10 USP43 DNAH5 IQCK	3.16e-05	167	160	6	cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACHE LMNTD2 PKHD1L1 KEL DNAJB2 FYB2	3.27e-05	168	160	6	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACHE LMNTD2 PKHD1L1 KEL DNAJB2 FYB2	3.27e-05	168	160	6	a61b39884851384cffd430079040546d125b2b40
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACHE HBD CR1L PHOSPHO1 KEL HBB	3.27e-05	168	160	6	360cd756067c8cfb6a78301674758eb5fac52c23
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACHE HBD CR1L PHOSPHO1 KEL HBB	3.27e-05	168	160	6	d791116040a9d3ea0485d68c974340116073986b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 USP43 CR1L IPCEF1 FYB2 TMEM117	3.38e-05	169	160	6	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPLANE2 BICDL2 DNAH10 USP43 DNAH5 IQCK	3.38e-05	169	160	6	30141f76e9bfc2b4586429857c72dbc85ba65cc9
Drug	Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A	RHBDF2 RRP1B UBXN6 GAS6 CHD8 MAPK8IP3 BTBD7 NFKBIB DNAJB2 IQCK	1.22e-06	198	157	10	7034_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MAN1C1 UBXN6 ALDH1L1 NCDN INF2 BTBD7 NFKBIB DNAJB2 AGRN MOCS1	1.28e-06	199	157	10	7439_UP
Drug	glimepiride	CAPN3 MAP3K14 LIPE EHMT1 HBB HBD	1.92e-06	54	157	6	CID000003476
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A	TUT4 MAN1C1 NOD2 PDE12 CDK13 BTBD7 KCNJ3 AGRN MOCS1	8.06e-06	193	157	9	3434_UP
Drug	(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; HL60; HG-U133A	TBRG4 CAPN1 MAPK8IP3 RNF170 SBNO1 SDHAF3 RPRD2 MMS19 LAS1L	9.51e-06	197	157	9	1780_DN
Drug	Viroxime	CPE HBB HBD	1.10e-05	7	157	3	CID000051567
Drug	AC1L9FD9	CAPN3 LIPE EHMT1 HBB HBD	1.97e-05	48	157	5	CID000443871
Drug	3H-AMT	FDFT1 HBB HBD	2.62e-05	9	157	3	CID000107680
Drug	tricapryl(methyl)ammonium	HBB HBD	4.72e-05	2	157	2	CID011071504
Drug	allyl 2,4,6-tribromophenyl ether	HBB HBD	4.72e-05	2	157	2	CID000076767
Drug	1,3,5-tribromobenzene	HBB HBD	4.72e-05	2	157	2	CID000012279
Drug	2-(alpha-hydroxybenzyl)-benzimidazole	HBB HBD	4.72e-05	2	157	2	CID000005792
Drug	NSC-334295	HBB HBD	4.72e-05	2	157	2	CID000100107
Drug	AC1L3OJQ	HBB HBD	4.72e-05	2	157	2	CID000119294
Drug	pentabromobenzene	HBB HBD	4.72e-05	2	157	2	CID000011854
Drug	tribromobenzene	HBB HBD	4.72e-05	2	157	2	CID000011842
Drug	Bromkal 73-5 PE	HBB HBD	4.72e-05	2	157	2	CID000118216
Drug	Lndfh-ii	NOD2 LIPE TPH1	5.10e-05	11	157	3	CID000124919
Drug	4-dimethylaminophenol	KEL HBB HBD	5.10e-05	11	157	3	CID000022173
Disease	Chromosome Instability Syndromes	PNKP WRN	2.78e-05	2	156	2	C1563697
Disease	DNA Repair-Deficiency Disorders	PNKP WRN	2.78e-05	2	156	2	C1563696
Disease	DNA Repair-Deficiency	PNKP WRN	2.78e-05	2	156	2	C0268134
Disease	triglyceride measurement, intermediate density lipoprotein measurement	DNAH10 CAPN3 GAS6 BPTF FDFT1 GLTPD2	2.84e-05	111	156	6	EFO_0004530, EFO_0008595
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	DNAH10 MYO1H CAPN3 GAS6 BPTF FDFT1 GLTPD2	3.03e-05	166	156	7	EFO_0004530, EFO_0004611
Disease	Delta-Beta Thalassemia	HBB HBD	8.30e-05	3	156	2	C0271985
Disease	beta thalassemia (implicated_via_orthology)	HBB HBD	8.30e-05	3	156	2	DOID:12241 (implicated_via_orthology)
Disease	Autism Spectrum Disorders	CHD8 TRIP12 NRXN1 TET3 UNC80	9.04e-05	85	156	5	C1510586
Disease	muscular dystrophy (is_implicated_in)	COL6A3 CAPN3 DYSF	9.33e-05	17	156	3	DOID:9884 (is_implicated_in)
Disease	triglyceride measurement, phospholipid measurement	DNAH10 COPB1 CAPN3 GAS6 BPTF FDFT1	1.31e-04	146	156	6	EFO_0004530, EFO_0004639
Disease	Intellectual Disability	PDGFRB CHD8 MAPK8IP3 BPTF FASN NRXN1 FDFT1 ASTN1 LAS1L TET3	1.41e-04	447	156	10	C3714756
Disease	autism spectrum disorder (implicated_via_orthology)	PDGFRB CHD9 CHD8 NRXN1 GPRASP2 TPH1	1.63e-04	152	156	6	DOID:0060041 (implicated_via_orthology)
Disease	response to cisplatin, platinum measurement	CCDC146 DYSF NRXN1 VAV2	1.80e-04	53	156	4	EFO_0010154, GO_0072718
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	DNAH10 COPB1 CAPN3 GAS6 BPTF FDFT1 GLTPD2	1.98e-04	224	156	7	EFO_0004530, EFO_0008317
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement	DNAH10 MYO1H CAPN3 GAS6 FDFT1	2.55e-04	106	156	5	EFO_0008317, EFO_0008596
Disease	hereditary spastic paraplegia 76 (implicated_via_orthology)	CAPN1 CAPN3	2.75e-04	5	156	2	DOID:0110821 (implicated_via_orthology)
Disease	hemoglobin measurement, hemoglobin A2 measurement	HBD HBD	2.75e-04	5	156	2	EFO_0004509, EFO_0005845
Disease	free cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	DNAH10 MYO1H CAPN3 GAS6 FDFT1	3.03e-04	110	156	5	EFO_0008317, EFO_0008591, EFO_0008596
Disease	larynx cancer (is_implicated_in)	ERCC5 NOD2	4.11e-04	6	156	2	DOID:2596 (is_implicated_in)
Disease	hemoglobin E disease	HBD HBD	4.11e-04	6	156	2	MONDO_0016243
Disease	schizophrenia (implicated_via_orthology)	PDGFRB NRXN1 SBNO1 ASTN1	4.71e-04	68	156	4	DOID:5419 (implicated_via_orthology)
Disease	anemia (biomarker_via_orthology)	HBB HBD	5.73e-04	7	156	2	DOID:2355 (biomarker_via_orthology)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD8	5.73e-04	7	156	2	DOID:0050834 (implicated_via_orthology)
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	DYSF OTOF	5.73e-04	7	156	2	DOID:11724 (implicated_via_orthology)
Disease	joint hypermobility measurement	TUT4 FNDC1 VCAN	7.04e-04	33	156	3	EFO_0007905
Disease	Abnormality of the face	FDFT1 TET3	9.76e-04	9	156	2	C4025871
Disease	visceral heterotaxy (implicated_via_orthology)	CPLANE2 MEGF8 DNAH5	9.87e-04	37	156	3	DOID:0050545 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	DNAH10 COPB1 CAPN3 GAS6 BPTF FDFT1	1.15e-03	220	156	6	EFO_0004529, EFO_0008317
Disease	Abnormality of nervous system morphology	MAPK8IP3 FDFT1	1.22e-03	10	156	2	C4022810
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	DNAH10 COPB1 CAPN3 GAS6 BPTF FDFT1	1.41e-03	229	156	6	EFO_0004639, EFO_0008317
Disease	Macrocephaly	CHD8 TET3	1.48e-03	11	156	2	C0221355
Disease	hereditary spastic paraplegia (implicated_via_orthology)	CAPN1 CAPN3 RNF170	1.53e-03	43	156	3	DOID:2476 (implicated_via_orthology)
Disease	high grade glioma (implicated_via_orthology)	POLE INSRR SIRT2	1.64e-03	44	156	3	DOID:3070 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	ACHE DYSF HDAC7 AURKA FASN LIPE ARAP3 OTOF SBNO1 PRICKLE3 ITSN2 EHMT1 TMEM39A PADI3	1.74e-03	1074	156	14	C0006142
Disease	waist circumference	DNAH10 ALDH1L1 BPTF FASN NRXN1 DNAH5 PADI3 IQCK	2.09e-03	429	156	8	EFO_0004342
Disease	melanoma	ERCC5 CAPN1 AURKA FASN CPT1C SYT4	2.11e-03	248	156	6	C0025202
Disease	waist-hip ratio	DNAH10 COPB1 CCDC146 DUSP6 MAP3K14 TRIP12 CEMIP DNAJA3 BPTF CCM2 MEGF8 NID1 SYT4 ASPSCR1 IQCK	2.22e-03	1226	156	15	EFO_0004343
Disease	Autosomal recessive limb-girdle muscular dystrophy	CAPN3 DYSF	2.42e-03	14	156	2	cv:C2931907
Disease	diffuse large B-cell lymphoma	ARAP3 ITSN2	2.42e-03	14	156	2	EFO_0000403
Disease	very low density lipoprotein cholesterol measurement	DNAH10 COPB1 CAPN3 GAS6 BPTF FDFT1	2.67e-03	260	156	6	EFO_0008317
Disease	chylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement	DNAH10 CAPN3 GAS6 FDFT1	2.81e-03	110	156	4	EFO_0004574, EFO_0008317, EFO_0008596
Disease	pneumonia (is_implicated_in)	C5 SOD3	3.17e-03	16	156	2	DOID:552 (is_implicated_in)
Disease	Colorectal Carcinoma	POLE WRN CPE GATA5 ALDH1L1 NCDN AURKA ARAP3 NID1 LAS1L	4.28e-03	702	156	10	C0009402
Disease	CCL2 measurement	PDGFRB ABCA7 HDAC7 TMEM117	4.57e-03	126	156	4	EFO_0004749
Disease	Malignant Neoplasms	CAPN1 WRN AURKA FASN	4.83e-03	128	156	4	C0006826
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	DNAH10 COPB1 CAPN3 BPTF FDFT1	4.87e-03	206	156	5	EFO_0004612, EFO_0020947

Protein segments in the cluster

Peptide	Gene	Start	Entry
GFPFVLAARFSDRTA	URAD	116	A6NGE7
FRFSFVPVVDGDFLS	ACHE	326	P22303
QPFSLVRSFRLGFEA	ACSM6	6	Q6P461
FFRPSETVGDLRDFV	ASPSCR1	406	Q9BZE9
AIDRFSKPDSDRFVF	CHD8	1191	Q9HCK8
DPGDRFPFSFELILA	ARAP3	746	Q8WWN8
FTFPDFVTEGARDLI	AURKA	346	O14965
IRGFSTGFPLEEDFS	VCAN	1921	P13611
PILISFFEGRFESTI	ARMH2	146	H3BNL8
AFEGRSFLAFPTLRA	AGRN	1376	O00468
SPFFRALLSGSFAEA	ARMC5	771	Q96C12
IDFLDRAIFDGASTP	CCM2	226	Q9BSQ5
DLSLELLFPESFGFI	CA11	221	O75493
ELESSVSFPADFFRP	CELSR1	2276	Q9NYQ6
FEPNKEGDFVLRFFS	CAPN1	501	P07384
FGTVLRLSPFRFEDF	BPTF	256	Q12830
DEPSIAEGKRLFSFF	BICDL1	556	Q6ZP65
SRRPVFNEDFFFDGL	C2CD4C	366	Q8TF44
AFEDVPITSRVFFGE	CEMIP	926	Q8WUJ3
REEFVFIPAAALDLF	CDK13	961	Q14004
FDSLEVLLDSFGPVR	ASTN1	596	O14525
AFVAAEFPGAELREA	ABCA7	2036	Q8IZY2
DPFINELVLFIFSGS	OR5K2	191	Q8NHB8
TFAPEADGTIFFPER	ARHGAP39	256	Q9C0H5
LFDRDQFSPDDFLGR	ITSN2	1636	Q9NZM3
RAGEPFTEFFSIPFV	IQCK	181	Q8N0W5
LDEASSPGEFAVFLL	BEND3	401	Q5T5X7
QGISPERAFADFLFA	DAD1	86	P61803
AFPELDFRSGARVEE	MB21D2	21	Q8IYB1
TPLGSVFAFATREAF	GLTPD2	116	A6NH11
ADLLGEFSVRDDFFG	MAPK8IP3	401	Q9UPT6
IFDAVGFTFPNRLLT	NCDN	76	Q9UBB6
RGPGFFREEITTFID	GPR162	496	Q16538
ISRDYSLGPFVEELF	MMS19	201	Q96T76
DPDFVDALTEFGIFS	FICD	136	Q9BVA6
GATAVAFSSFDPRLF	DYNC2I2	336	Q96EX3
AFSSFDPRLFILGTE	DYNC2I2	341	Q96EX3
DIFIELVTNPDGFAF	CPA5	231	Q8WXQ8
SFEGEFTKPTFLELL	CCDC190	236	Q86UF4
IGLSRLFSASEFEDP	FDFT1	181	P37268
EDIVFPFGTAELFAT	CFAP52	336	Q8N1V2
EPFLDFLLGFSAGTE	NFKBIB	71	Q15653
VFSDSLVPALEAFGL	PDE12	356	Q6L8Q7
FGAVAPFLADLDTTD	NID1	101	P14543
PLRGFLLDGDFFVAA	COPB1	541	P53618
ISQEDFERLSGNFPF	RASGRP4	486	Q8TDF6
VLAFDGFPRFLDTGV	MEGF8	1341	Q7Z7M0
AVLDAFLDDGFLVPT	LAS1L	321	Q9Y4W2
FLDDGFLVPTFEQLA	LAS1L	326	Q9Y4W2
VFADGTDLSIDRFPL	LMNTD2	476	Q8IXW0
PEEKGITFDEFRSFF	MICU3	416	Q86XE3
IFNAPSDDEEFVGFR	CDCA7L	16	Q96GN5
PEDISTFGSDLFFAR	POLE	1661	Q07864
FDFRTTEPNGLILFS	NRXN1	506	Q9ULB1
EERFFVEGLSFPDAG	PADI3	246	Q9ULW8
DSFFFSIVRDPAALA	GAL3ST4	151	Q96RP7
EPDFSSIERLFSFPA	INF2	596	Q27J81
DFAALTEGLPLDVRF	MOCS1	231	Q9NZB8
RVPFEAFLASFQALG	MYO15B	271	Q96JP2
SSEDDGFFLGERIPL	PRICKLE3	556	O43900
LILSFDFSAGDPFET	PLA2G4C	406	Q9UP65
AAFFVSLDAEPAGLT	CPT1C	411	Q8TCG5
FLFSFTDRASFEDLP	CPLANE2	141	Q9BU20
RPTFVSDFLEEFPGE	GATA5	171	Q9BWX5
STFGVVFDPDRGQFD	CHD9	1851	Q3L8U1
FEFDPELVLVSAGFD	HDAC10	251	Q969S8
DGFVNLPDFTVERAS	IPCEF1	86	Q8WWN9
FLRDVFADEFIFLPG	GNPAT	516	O15228
ALEDDGFRLFFTSVP	CUSTOS	116	Q96C57
APATVGLAFRADDTF	ELOB	71	Q15370
GRTEASPFFTDEFAL	LINC02876	61	F2Z3M2
REFFGGQDPFSFDLL	DNAJB3	101	Q8WWF6
GFTFTFRSPEEVFRE	DNAJB2	91	P25686
FRSPEEVFREFFGSG	DNAJB2	96	P25686
SFPEEEFDLAGRKRF	FNDC1	1596	Q4ZHG4
PTRLVAEFDFRTFDP	GAS6	316	Q14393
AEFDFRTFDPEGILL	GAS6	321	Q14393
PTVFAFDERVFLEAF	COL6A5	1896	A8TX70
RFRIFELFEVGFLSP	C5	1476	P01031
ELFEVGFLSPATFTV	C5	1481	P01031
LPFARPTNLTDDFEF	CR1L	41	Q2VPA4
STEIKRDLFGAEPFD	GULP1	246	Q9UBP9
DNLVFTVPEFRSFGD	COL6A3	396	P12111
AFDSSLVFIPAEFRA	COL6A3	596	P12111
GFAVRLVFQDFDLEP	C1RL	76	Q9NZP8
GVTPDDLDAFVRFEF	CC2D1B	716	Q5T0F9
PAAGVDFELESFSER	CPE	441	P16870
DLDRFFTINPEDGFI	CDH11	426	P55287
KFFPDERFGDESPLL	BTBD7	711	Q9P203
SGDEGFFPFVLERRD	BICDL2	21	A1A5D9
FFPFVLERRDSFLGG	BICDL2	26	A1A5D9
ISDSDELASGFFVFP	FDCSP	31	Q8NFU4
DLFPGTFQTIELFAD	HEPHL1	1026	Q6MZM0
DEGVPFRFDFNAFRS	MAN1C1	136	Q9NR34
FTATGEDFRGLSFPR	INSRR	61	P14616
ILPFVAEFEEFAGLA	EXOC1	671	Q9NV70
RFFESFGDLSSPDAV	HBD	41	P02042
RFFESFGDLSTPDAV	HBB	41	P68871
AREFSPDLVLVSAGF	HDAC7	786	Q8WUI4
ANRLSFFFDFRGPSI	FASN	141	P49327
FFFDFRGPSIALDTA	FASN	146	P49327
FTGGVAEFFEIRDAP	CAPN3	231	P20807
AFFTREFTGLEPIVS	COCH	521	O43405
DPEELFRKIFGEFSS	DNAJA3	181	Q96EY1
FFPEAISFIDEARGK	DUSP6	271	Q16828
FEDVPLFLGLISDLF	DNAH10	2046	Q8IVF4
FSPVVERLGFDENFV	POLI	141	Q9UNA4
FRESFADVLPEAAAL	RPRD2	96	Q5VT52
FGTFLPEEKLNDFRD	SDHAF3	81	Q9NRP4
EGTPFREFSDFIQAV	SBNO1	496	A3KN83
LFFNLFDSPGELFDE	DYSF	266	O75923
FPRIAFFSTRLIEAG	EHMT1	1221	Q9H9B1
ILFFDEFESIAPRRG	PEX1	936	O43933
RFFFVSDPALLEILG	DNAH5	1716	Q8TE73
FVDFLRDAPEAAGET	DNAH5	2871	Q8TE73
VLLDSDGEFLPVRDF	TBRG4	526	Q969Z0
LFFEGDEGLTADFLR	LIPE	441	Q05469
DSSGLSDPFARVFFI	OTOF	976	Q9HC10
GFLPNDAEELFIFLT	PDGFRB	126	P09619
EFSPTFSERIFIAGS	MAP3K14	91	Q99558
LRKTLDPAFDETFTF	SYT4	211	Q9H2B2
LRAESDFVKFDTPFL	RRP1B	636	Q14684
SFSGEVLFRSPEFVD	TCP11X2	246	Q5H9J9
FGDLDPSSAEFFLQE	NIN	516	Q8N4C6
PELFERFLGADFPFT	NKPD1	496	Q17RQ9
RFLGADFPFTVAEAQ	NKPD1	501	Q17RQ9
DDFSLEPLISAFREF	GPRASP2	801	Q96D09
EGSLSPERLFNAEFE	FYB2	311	Q5VWT5
LFFRIRPIFVFDGDA	ERCC5	66	P28715
PEALFGILGFLDDFF	RNF170	221	Q96K19
DIVFFGESLPARFFS	SIRT2	231	Q8IXJ6
APFVLEASEIGSDLF	TECTB	171	Q96PL2
RKSVFEDDLPFLEFT	WRN	36	Q14191
FEAPTLAEGFSAILE	PNKP	486	Q96T60
AFPADFIAEGIDQTR	IARS1	551	P41252
EEFDRTSRFTPPAFI	PHF24	91	Q9UPV7
TVDSFRPGFDVALPF	EXTL1	186	Q92935
IDGLSQPESFDFRTD	SRBD1	886	Q8N5C6
RPGFFFEPTVFTDVE	ALDH1L1	781	O75891
ERFVDLSETPAFIFL	CCDC146	36	Q8IYE0
IIESFFPDGSQRVDF	CHP2	66	O43745
IGRLFGETLSFIFPE	CLCNKB	436	P51801
SQELSPVGLFELFFD	PGBD2	136	Q6P3X8
LSPRDFLSGLAFRVF	TPH1	236	P17752
FELPGDFFNLTAEEI	UBXN6	286	Q9BZV1
PSGFQRSFFDEEDLN	USP43	331	Q70EL4
PSFPRSAIDAEFSLF	UNC80	2131	Q8N2C7
PDRVLLTFDGFDEFK	NOD2	371	Q9HC29
VSVLVFDFRPSLEFF	SLC35A5	346	Q9BS91
FDFRPSLEFFLEAPS	SLC35A5	351	Q9BS91
AKLDAFFALEGFPTE	SOD3	91	P08294
DLPVDGSLLFEFLFF	TMEM39A	66	Q9NV64
DPDATRFFGEALEFN	ZNF592	231	Q92610
FSTFELFLTIIDGPA	TRPV6	571	Q9H1D0
SASREIAAFFPDFSE	NME6	136	O75414
AQGAPRFLLTFDFDE	PHOSPHO1	21	Q8TCT1
DTFVARFSGFLVAPD	PKHD1L1	386	Q86WI1
IRQFEAEFGDSFGLP	TET3	711	O43151
LDDGFFPFIILDAIN	YLPM1	1921	P49750
TQIFFGFEDEPDARF	ZNFX1	1571	Q9P2E3
FLPSDEVSRAFLASF	TMEM117	231	Q9H0C3
FGLRNSELFDPFDLF	VAV2	86	P52735
RQFDSFRDGFESVFP	TRIP12	1836	Q14669
YFFDSRVLTDGELAP	TUT4	1276	Q5TAX3
SFAFPSFLEEDVVDG	RHBDF2	271	Q6PJF5
FTPEFREALFSLGPE	USP40	61	Q9NVE5
RELFEEFDSFLPGAI	XXYLT1	236	Q8NBI6
TFFEPTLAALFVREA	KEL	416	P23276
PSAFLFFIETEATIG	KCNJ3	131	P48549
FIRFPRTLFATEDAF	MYO1H	686	Q8N1T3
FEEIGKRFGPFDLAA	NAPEPLD	291	Q6IQ20