Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3-phosphoinositide-dependent protein kinase activity

PDPK2P PDPK1

4.32e-062422GO:0004676
GeneOntologyMolecularFunctioniron ion binding

CYP4F3 KDM7A TYW5 AOX1

4.03e-04166424GO:0005506
GeneOntologyMolecularFunctionactin binding

EZR RDX GBP3 MYO5A MYO7A MSN

4.66e-04479426GO:0003779
GeneOntologyMolecularFunctionmodification-dependent protein binding

PHF1 KDM7A SIRT1 ATAD2B

9.06e-04206424GO:0140030
GeneOntologyMolecularFunctionphospholipase activator activity

PDPK2P PDPK1

1.06e-0323422GO:0016004
GeneOntologyMolecularFunctionlipase activator activity

PDPK2P PDPK1

1.47e-0327422GO:0060229
GeneOntologyMolecularFunctionlysine-acetylated histone binding

SIRT1 ATAD2B

1.81e-0330422GO:0070577
GeneOntologyMolecularFunctioninsulin receptor binding

PDPK2P PDPK1

1.81e-0330422GO:0005158
GeneOntologyMolecularFunctioncytoskeletal protein binding

EZR RDX GBP3 MYO5A MYO7A EML3 HDGFL3 MSN

1.82e-031099428GO:0008092
GeneOntologyMolecularFunctionacetylation-dependent protein binding

SIRT1 ATAD2B

1.93e-0331422GO:0140033
GeneOntologyMolecularFunctionphospholipase binding

PDPK2P PDPK1

2.06e-0332422GO:0043274
GeneOntologyMolecularFunctionhistone binding

PHF1 KDM7A SIRT1 ATAD2B

2.28e-03265424GO:0042393
GeneOntologyMolecularFunctionspectrin binding

GBP3 MYO7A

2.32e-0334422GO:0030507
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO5A MYO7A

2.89e-0338422GO:0000146
GeneOntologyMolecularFunctiondisordered domain specific binding

EZR MYO5A

3.05e-0339422GO:0097718
GeneOntologyMolecularFunctionprotein kinase A binding

EZR RDX

6.63e-0358422GO:0051018
GeneOntologyMolecularFunctionG protein activity

GBP3 GBP5

6.85e-0359422GO:0003925
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F3 KDM7A TYW5

7.85e-03194423GO:0016705
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM7A TYW5

8.26e-0365422GO:0016706
GeneOntologyMolecularFunctionATP-dependent activity

MYO5A MYO7A SNRNP200 DDX60 ATAD2B

8.99e-03614425GO:0140657
GeneOntologyMolecularFunctionprotein kinase binding

EZR PDPK2P MYO5A PDPK1 SIRT1 MSN

9.38e-03873426GO:0019901
GeneOntologyMolecularFunctionprotein domain specific binding

EZR RDX PLXND1 MYO5A MYO7A SIRT1

9.48e-03875426GO:0019904
GeneOntologyMolecularFunctionNAD binding

SIRT1 AOX1

1.03e-0273422GO:0051287
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

TYW5 SNRNP200 DDX60 FTSJ3

1.12e-02417424GO:0140098
GeneOntologyMolecularFunctionRNA helicase activity

SNRNP200 DDX60

1.17e-0278422GO:0003724
GeneOntologyMolecularFunctiondouble-stranded RNA binding

DDX60 MSN

1.17e-0278422GO:0003725
GeneOntologyMolecularFunctionactin filament binding

EZR MYO5A MYO7A

1.20e-02227423GO:0051015
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

SNRNP200 DDX60

1.23e-0280422GO:0008186
GeneOntologyBiologicalProcesspositive regulation of early endosome to late endosome transport

EZR RDX MSN

6.54e-079423GO:2000643
GeneOntologyBiologicalProcessregulation of protein localization to early endosome

EZR RDX MSN

9.33e-0710423GO:1902965
GeneOntologyBiologicalProcesspositive regulation of protein localization to early endosome

EZR RDX MSN

9.33e-0710423GO:1902966
GeneOntologyBiologicalProcesspositive regulation of protein localization to endosome

EZR RDX MSN

2.81e-0614423GO:1905668
GeneOntologyBiologicalProcessregulation of protein localization to endosome

EZR RDX MSN

3.51e-0615423GO:1905666
GeneOntologyBiologicalProcessprotein localization to early endosome

EZR RDX MSN

4.32e-0616423GO:1902946
GeneOntologyBiologicalProcessregulation of early endosome to late endosome transport

EZR RDX MSN

8.74e-0620423GO:2000641
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP3 GBP5

2.42e-054422GO:0140973
GeneOntologyBiologicalProcessregulation of response to biotic stimulus

GBP3 RNF216 PDPK2P GBP5 DDX60 PDPK1 HERC5 IL21

3.95e-05643428GO:0002831
GeneOntologyBiologicalProcessprotein localization to endosome

EZR RDX MSN

4.10e-0533423GO:0036010
GeneOntologyBiologicalProcessregulation of pattern recognition receptor signaling pathway

GBP3 PDPK2P GBP5 DDX60 PDPK1

4.37e-05193425GO:0062207
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP3 GBP5

6.04e-056422GO:0140971
GeneOntologyBiologicalProcessdefense response to virus

GBP3 RNF216 GBP5 DDX60 HERC5 IL21

6.31e-05342426GO:0051607
GeneOntologyBiologicalProcessestablishment of organelle localization

EZR PDPK2P MYO5A MYO7A EML3 PDPK1 SIRT1

1.06e-04546427GO:0051656
GeneOntologyBiologicalProcessAIM2 inflammasome complex assembly

GBP3 GBP5

1.12e-048422GO:0140970
GeneOntologyBiologicalProcessnegative regulation of cardiac muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

1.44e-0450423GO:0010667
GeneOntologyBiologicalProcessearly endosome to late endosome transport

EZR RDX MSN

1.44e-0450423GO:0045022
GeneOntologyBiologicalProcesscytolysis in another organism

GBP3 GBP5

1.44e-049422GO:0051715
GeneOntologyBiologicalProcesspositive regulation of pyroptotic inflammatory response

GBP3 GBP5

1.44e-049422GO:0140639
GeneOntologyBiologicalProcessnegative regulation of striated muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

1.81e-0454423GO:0010664
GeneOntologyBiologicalProcesspositive regulation of innate immune response

GBP3 PDPK2P GBP5 DDX60 PDPK1 IL21

1.94e-04420426GO:0045089
GeneOntologyBiologicalProcessvesicle-mediated transport between endosomal compartments

EZR RDX MSN

2.02e-0456423GO:0098927
GeneOntologyBiologicalProcessresponse to virus

GBP3 RNF216 GBP5 DDX60 HERC5 IL21

2.07e-04425426GO:0009615
GeneOntologyBiologicalProcessepithelial cell development

EZR RDX PDPK2P PDPK1 MSN

2.08e-04269425GO:0002064
GeneOntologyBiologicalProcessestablishment of endothelial barrier

EZR RDX MSN

2.24e-0458423GO:0061028
GeneOntologyBiologicalProcesspositive regulation of immune response

EZR GBP3 PDPK2P GBP5 DDX60 PDPK1 SIRT1 IL21

2.63e-04845428GO:0050778
GeneOntologyBiologicalProcesscytolysis

GBP3 GBP5

2.64e-0412422GO:0019835
GeneOntologyBiologicalProcesspositive regulation of response to biotic stimulus

GBP3 PDPK2P GBP5 DDX60 PDPK1 IL21

2.85e-04451426GO:0002833
GeneOntologyBiologicalProcessregulation of cell shape

EZR RDX PLXND1 MSN

3.03e-04159424GO:0008360
GeneOntologyBiologicalProcesscellular response to testosterone stimulus

SIRT1 MSN

3.11e-0413422GO:0071394
GeneOntologyBiologicalProcesspattern recognition receptor signaling pathway

GBP3 PDPK2P GBP5 DDX60 PDPK1

3.14e-04294425GO:0002221
GeneOntologyBiologicalProcessregulation of vesicle-mediated transport

EZR RDX RNF216 PDPK2P MYO5A PDPK1 MSN

3.61e-04667427GO:0060627
GeneOntologyBiologicalProcesspositive regulation of protein localization to plasma membrane

EZR MYO5A PDPK1

3.91e-0470423GO:1903078
GeneOntologyBiologicalProcessinnate immune response-activating signaling pathway

GBP3 PDPK2P GBP5 DDX60 PDPK1

4.12e-04312425GO:0002758
GeneOntologyBiologicalProcessorganelle localization

EZR PDPK2P MYO5A MYO7A EML3 PDPK1 SIRT1

4.95e-04703427GO:0051640
GeneOntologyBiologicalProcessactivation of innate immune response

GBP3 PDPK2P GBP5 DDX60 PDPK1

5.55e-04333425GO:0002218
GeneOntologyBiologicalProcesspositive regulation of pattern recognition receptor signaling pathway

GBP3 GBP5 DDX60

5.57e-0479423GO:0062208
GeneOntologyBiologicalProcessendothelial cell development

EZR RDX MSN

5.78e-0480423GO:0001885
GeneOntologyBiologicalProcessregulation of innate immune response

GBP3 PDPK2P GBP5 DDX60 PDPK1 IL21

5.99e-04519426GO:0045088
GeneOntologyBiologicalProcesspositive regulation of protein localization to cell periphery

EZR MYO5A PDPK1

6.22e-0482423GO:1904377
GeneOntologyBiologicalProcessregulation of cardiac muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

6.67e-0484423GO:0010665
GeneOntologyBiologicalProcessnegative regulation of muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

7.39e-0487423GO:0010656
GeneOntologyBiologicalProcessregulation of striated muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

7.64e-0488423GO:0010662
GeneOntologyBiologicalProcesscardiac muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

8.15e-0490423GO:0010659
GeneOntologyBiologicalProcessestablishment of epithelial cell apical/basal polarity

EZR MSN

8.29e-0421422GO:0045198
GeneOntologyBiologicalProcessimmune response-activating signaling pathway

EZR GBP3 PDPK2P GBP5 DDX60 PDPK1

8.35e-04553426GO:0002757
GeneOntologyBiologicalProcessregulation of defense response

GBP3 RNF216 PDPK2P GBP5 DDX60 PDPK1 HERC5 IL21

8.37e-041006428GO:0031347
GeneOntologyBiologicalProcessstriated muscle cell apoptotic process

PDPK2P PDPK1 SIRT1

9.25e-0494423GO:0010658
GeneOntologyBiologicalProcessDNA repair-dependent chromatin remodeling

PHF1 SIRT1

9.97e-0423422GO:0140861
GeneOntologyBiologicalProcesspigment granule transport

MYO5A MYO7A

9.97e-0423422GO:0051904
GeneOntologyBiologicalProcessestablishment of pigment granule localization

MYO5A MYO7A

1.09e-0324422GO:0051905
GeneOntologyBiologicalProcesspositive regulation of defense response

GBP3 PDPK2P GBP5 DDX60 PDPK1 IL21

1.16e-03589426GO:0031349
GeneOntologyBiologicalProcesspositive regulation of protein localization

EZR RDX MYO5A PDPK1 SIRT1 MSN

1.18e-03591426GO:1903829
GeneOntologyBiologicalProcessnegative regulation of toll-like receptor signaling pathway

PDPK2P PDPK1

1.18e-0325422GO:0034122
GeneOntologyBiologicalProcesspigment granule localization

MYO5A MYO7A

1.28e-0326422GO:0051875
GeneOntologyBiologicalProcesspositive regulation of inflammasome-mediated signaling pathway

GBP3 GBP5

1.28e-0326422GO:0141087
GeneOntologyBiologicalProcessestablishment of apical/basal cell polarity

EZR MSN

1.28e-0326422GO:0035089
GeneOntologyBiologicalProcessnegative regulation of neuron apoptotic process

PLXND1 PDPK2P PDPK1 SIRT1

1.33e-03236424GO:0043524
GeneOntologyBiologicalProcessregulation of immune response

EZR GBP3 PDPK2P GBP5 DDX60 PDPK1 SIRT1 IL21

1.36e-031085428GO:0050776
GeneOntologyBiologicalProcessimmune response-regulating signaling pathway

EZR GBP3 PDPK2P GBP5 DDX60 PDPK1

1.44e-03615426GO:0002764
GeneOntologyBiologicalProcessestablishment of monopolar cell polarity

EZR MSN

1.48e-0328422GO:0061162
GeneOntologyBiologicalProcessmicrovillus assembly

EZR RDX

1.48e-0328422GO:0030033
GeneOntologyBiologicalProcessactivation of immune response

EZR GBP3 PDPK2P GBP5 DDX60 PDPK1

1.54e-03623426GO:0002253
GeneOntologyBiologicalProcesstype B pancreatic cell development

PDPK2P PDPK1

1.59e-0329422GO:0003323
GeneOntologyBiologicalProcessestablishment or maintenance of monopolar cell polarity

EZR MSN

1.59e-0329422GO:0061339
GeneOntologyBiologicalProcesspolarized epithelial cell differentiation

EZR MSN

1.70e-0330422GO:0030859
GeneOntologyBiologicalProcessmicrovillus organization

EZR RDX

2.18e-0334422GO:0032528
GeneOntologyBiologicalProcesscellular response to insulin stimulus

PDPK2P MYO5A PDPK1 SIRT1

2.20e-03271424GO:0032869
GeneOntologyCellularComponentmicrovillus

EZR RDX MYO7A CNP MSN

4.64e-06123425GO:0005902
GeneOntologyCellularComponentcell tip

EZR RDX MSN

5.03e-0617423GO:0051286
GeneOntologyCellularComponentcell pole

EZR RDX MSN

8.40e-0620423GO:0060187
GeneOntologyCellularComponentactin-based cell projection

EZR RDX MYO5A MYO7A CNP MSN

1.84e-05278426GO:0098858
GeneOntologyCellularComponentfilopodium

EZR RDX MYO5A MSN

1.07e-04123424GO:0030175
GeneOntologyCellularComponentsymbiont cell surface

GBP3 GBP5

1.10e-048422GO:0106139
GeneOntologyCellularComponentstereocilium base

RDX MYO7A

1.10e-048422GO:0120044
GeneOntologyCellularComponentother organism part

GBP3 GBP5

1.41e-049422GO:0044217
GeneOntologyCellularComponentunconventional myosin complex

MYO5A MYO7A

2.14e-0411422GO:0016461
GeneOntologyCellularComponenturopod

EZR MSN

3.53e-0414422GO:0001931
GeneOntologyCellularComponentapical plasma membrane

EZR RDX CYP4F3 MYO7A SLCO2B1 MSN

3.99e-04487426GO:0016324
GeneOntologyCellularComponentcell trailing edge

EZR MSN

4.07e-0415422GO:0031254
GeneOntologyCellularComponentESC/E(Z) complex

PHF1 SIRT1

5.26e-0417422GO:0035098
GeneOntologyCellularComponentT-tubule

EZR RDX MSN

5.36e-0479423GO:0030315
GeneOntologyCellularComponentpseudopodium

CNP MSN

5.91e-0418422GO:0031143
GeneOntologyCellularComponentmyelin sheath

EZR RDX CNP MSN

9.28e-04217424GO:0043209
GeneOntologyCellularComponentapical part of cell

EZR RDX CYP4F3 MYO7A SLCO2B1 MSN

1.11e-03592426GO:0045177
GeneOntologyCellularComponentmelanosome

MYO5A MYO7A CNP

1.51e-03113423GO:0042470
GeneOntologyCellularComponentpigment granule

MYO5A MYO7A CNP

1.51e-03113423GO:0048770
GeneOntologyCellularComponentperinuclear region of cytoplasm

SLC30A7 EZR GBP3 GBP5 CNP HERC5 MSN

2.39e-03934427GO:0048471
GeneOntologyCellularComponentmicrovillus membrane

EZR MSN

2.65e-0338422GO:0031528
GeneOntologyCellularComponentPcG protein complex

PHF1 SIRT1

4.90e-0352422GO:0031519
GeneOntologyCellularComponentactin cytoskeleton

EZR RDX GBP3 MYO5A MYO7A

5.72e-03576425GO:0015629
GeneOntologyCellularComponentmyosin complex

MYO5A MYO7A

6.27e-0359422GO:0016459
GeneOntologyCellularComponentsarcolemma

EZR RDX MSN

6.54e-03190423GO:0042383
MousePhenopancreatic islet hypoplasia

PDPK2P PDPK1

3.04e-054322MP:0009169
MousePhenoabsent dorsal root ganglion

PDPK2P PDPK1

5.06e-055322MP:0008460
MousePhenoabnormal presomitic mesoderm morphology

PDPK2P PDPK1

7.57e-056322MP:0012182
MousePhenodecreased adrenal gland zona fasciculata size

PDPK2P PDPK1

1.41e-048322MP:0014287
MousePhenoabsent heart tube

PDPK2P PDPK1

1.81e-049322MP:0012081
MousePhenoabnormal adrenal gland zona fasciculata size

PDPK2P PDPK1

2.76e-0411322MP:0014284
MousePhenoabnormal cephalic neural fold morphology

PDPK2P PDPK1

2.76e-0411322MP:0011259
MousePhenoabnormal pancreas size

PDPK2P PDPK1 SIRT1

2.93e-0457323MP:0009106
MousePhenofused inner hair cell stereocilia

RDX MYO7A

3.30e-0412322MP:0004533
MousePhenoabsent forebrain

PDPK2P PDPK1

4.54e-0414322MP:0012136
MousePhenoabsent heart

PDPK2P PDPK1

4.54e-0414322MP:0011388
MousePhenoimpaired pupillary reflex

MYO7A SNRNP200 MSN

4.73e-0467323MP:0006243
DomainERM_C_dom

EZR RDX MSN

3.92e-084413IPR011259
DomainERM

EZR RDX MSN

3.92e-084413IPR011174
DomainERM

EZR RDX MSN

3.92e-084413PF00769
DomainMoesin_tail

EZR RDX MSN

3.42e-077413IPR008954
DomainFERM_N

EZR RDX MYO7A MSN

7.81e-0733414IPR018979
DomainFERM_N

EZR RDX MYO7A MSN

7.81e-0733414PF09379
DomainFERM_M

EZR RDX MYO7A MSN

3.05e-0646414PF00373
DomainFERM_central

EZR RDX MYO7A MSN

3.94e-0649414IPR019748
DomainFERM_domain

EZR RDX MYO7A MSN

3.94e-0649414IPR000299
Domain-

EZR RDX MYO7A MSN

3.94e-06494141.20.80.10
DomainFERM_1

EZR RDX MYO7A MSN

4.28e-0650414PS00660
DomainFERM_2

EZR RDX MYO7A MSN

4.28e-0650414PS00661
DomainBand_41_domain

EZR RDX MYO7A MSN

4.28e-0650414IPR019749
DomainB41

EZR RDX MYO7A MSN

4.28e-0650414SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

EZR RDX MYO7A MSN

4.28e-0650414IPR014352
DomainFERM_3

EZR RDX MYO7A MSN

4.28e-0650414PS50057
DomainEz/rad/moesin-like

EZR RDX MSN

1.27e-0521413IPR000798
DomainFERM_CS

EZR RDX MSN

1.92e-0524413IPR019747
Domain-

EZR RDX MYO7A DOCK11 PDPK1 RABGAP1L MSN

2.03e-053914172.30.29.30
DomainFERM_C

EZR RDX MSN

2.46e-0526413PF09380
DomainFERM_C

EZR RDX MSN

2.77e-0527413SM01196
DomainFERM_PH-like_C

EZR RDX MSN

2.77e-0527413IPR018980
DomainPH_dom-like

EZR RDX MYO7A DOCK11 PDPK1 RABGAP1L MSN

3.52e-05426417IPR011993
DomainGBP_C

GBP3 GBP5

2.09e-0410412PF02841
DomainGuanylate-bd_C

GBP3 GBP5

2.55e-0411412IPR003191
DomainGBP

GBP3 GBP5

2.55e-0411412PF02263
DomainG_GB1_RHD3_dom

GBP3 GBP5

2.55e-0411412IPR030386
DomainGuanylate-bd_N

GBP3 GBP5

2.55e-0411412IPR015894
DomainG_GB1_RHD3

GBP3 GBP5

2.55e-0411412PS51715
DomainP-loop_NTPase

GBP3 GBP5 MYO5A MYO7A SNRNP200 DDX60 CNP ATAD2B

4.40e-04848418IPR027417
DomainUbiquitin-rel_dom

EZR RDX MYO7A MSN

6.94e-04184414IPR029071
Domain-

GBP3 GBP5 MYO7A SNRNP200 DDX60 CNP ATAD2B

1.08e-037464173.40.50.300
DomainJMJC

KDM7A TYW5

2.24e-0332412PS51184
DomainJmjC_dom

KDM7A TYW5

2.24e-0332412IPR003347
DomainJmjC

KDM7A TYW5

2.38e-0333412SM00558
DomainMYOSIN_MOTOR

MYO5A MYO7A

3.14e-0338412PS51456
DomainMyosin_head

MYO5A MYO7A

3.14e-0338412PF00063
DomainMyosin_head_motor_dom

MYO5A MYO7A

3.14e-0338412IPR001609
DomainMYSc

MYO5A MYO7A

3.14e-0338412SM00242
PathwayWP_PTDINS45P2_IN_CYTOKINESIS_PATHWAY

EZR RDX MSN

2.53e-0612333M45558
PathwayREACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA

EZR RDX MYO7A MSN

7.80e-0655334M41823
PathwayREACTOME_SENSORY_PROCESSING_OF_SOUND

EZR RDX MYO7A MSN

2.99e-0577334M41822
PathwayREACTOME_ESTROGEN_STIMULATED_SIGNALING_THROUGH_PRKCZ

PDPK2P PDPK1

7.92e-056332MM15665
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

EZR RDX MSN

8.60e-0537333MM15102
PathwayWP_GLIAL_CELL_DIFFERENTIATION

CNP MSN

1.47e-048332M39372
PathwayPID_RHOA_PATHWAY

EZR RDX MSN

1.55e-0445333M12
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

EZR RDX MSN

2.00e-0449333M891
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

PDPK2P PDPK1

4.08e-0413332MM15171
PathwayREACTOME_L1CAM_INTERACTIONS

EZR RDX MSN

5.28e-0468333MM14968
PathwayBIOCARTA_PTDINS_PATHWAY

PDPK2P PDPK1

6.25e-0416332MM1454
PathwayBIOCARTA_PTEN_PATHWAY

PDPK2P PDPK1

7.94e-0418332MM1461
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

EZR RDX PLXND1 MYO5A SIRT1 MSN

9.66e-04502336MM14537
PathwayBIOCARTA_MTOR_PATHWAY

PDPK2P PDPK1

9.83e-0420332MM1437
PathwayWP_LEPTININSULIN_SIGNALING_OVERLAP

PDPK2P PDPK1

9.83e-0420332MM15867
PathwayBIOCARTA_IGF1MTOR_PATHWAY

PDPK2P PDPK1

9.83e-0420332MM1496
PathwayBIOCARTA_GSK3_PATHWAY

PDPK2P PDPK1

1.19e-0322332MM1421
PathwayBIOCARTA_EIF4_PATHWAY

PDPK2P PDPK1

1.30e-0323332MM1470
PathwayWP_PURINE_METABOLISM_AND_RELATED_DISORDERS

PAICS AOX1

1.30e-0323332M39766
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PKNS

PDPK2P PDPK1

1.30e-0323332MM15216
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

PDPK2P PDPK1

1.30e-0323332MM14993
PathwayBIOCARTA_AKT_PATHWAY

PDPK2P PDPK1

1.67e-0326332MM1345
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

PDPK2P PDPK1

1.67e-0326332MM15017
PathwayREACTOME_INTEGRIN_SIGNALING

PDPK2P PDPK1

1.93e-0328332MM14958
PathwayREACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

PDPK2P PDPK1

2.22e-0330332MM15170
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

PDPK2P PDPK1

2.68e-0333332MM15027
PathwayREACTOME_L1CAM_INTERACTIONS

EZR RDX MSN

2.79e-03121333M872
PathwayREACTOME_CD28_CO_STIMULATION

PDPK2P PDPK1

2.84e-0334332MM14992
PathwayREACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE

PDPK2P PDPK1

3.01e-0335332MM14512
PathwayREACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING

RNF216 HERC5

3.01e-0335332M985
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

EZR RDX PLXND1 MSN

3.08e-03261334MM15676
PathwayREACTOME_REGULATION_OF_TP53_DEGRADATION

PDPK2P PDPK1

3.19e-0336332MM15339
Pubmed

The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.

EZR RDX MSN

1.76e-0934338479753
Pubmed

Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.

EZR RDX MSN

1.76e-09343318261459
Pubmed

Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.

EZR RDX MSN

1.76e-09343321659656
Pubmed

Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.

EZR RDX MSN

1.76e-09343319064715
Pubmed

Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.

EZR RDX MSN

1.76e-09343331843195
Pubmed

Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.

EZR RDX MSN

1.76e-09343321864676
Pubmed

Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.

EZR RDX MSN

1.76e-09343314613898
Pubmed

Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.

EZR RDX MSN

1.76e-09343321278069
Pubmed

Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.

EZR RDX MSN

1.76e-09343326555866
Pubmed

Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.

EZR RDX MSN

1.76e-09343323703860
Pubmed

Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.

EZR RDX MSN

1.76e-09343316889625
Pubmed

Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.

EZR RDX MSN

1.76e-09343315149851
Pubmed

Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.

EZR RDX MSN

1.76e-09343321837648
Pubmed

ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.

EZR RDX MSN

1.76e-09343321352885
Pubmed

Ezrin and moesin function together to promote T cell activation.

EZR RDX MSN

1.76e-09343319124745
Pubmed

A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.

EZR RDX MSN

1.76e-0934331429901
Pubmed

ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.

EZR RDX MSN

1.76e-09343332098334
Pubmed

Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.

EZR RDX MSN

1.76e-09343318295815
Pubmed

Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.

EZR RDX MSN

1.76e-09343312360288
Pubmed

Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.

EZR RDX MSN

1.76e-09343322132106
Pubmed

Dynamics and function of ERM proteins during cytokinesis in human cells.

EZR RDX MSN

1.76e-09343328889652
Pubmed

Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.

EZR RDX MSN

1.76e-09343323116763
Pubmed

Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.

EZR RDX MSN

1.76e-09343321451358
Pubmed

Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.

EZR RDX MSN

1.76e-09343319321616
Pubmed

Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.

EZR RDX MSN

1.76e-09343329906485
Pubmed

Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.

EZR RDX MSN

1.76e-09343320679347
Pubmed

Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.

EZR RDX MSN

1.76e-09343312385025
Pubmed

Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?

EZR RDX MSN

1.76e-09343325286001
Pubmed

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

EZR RDX MSN

1.76e-09343317977945
Pubmed

Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.

EZR RDX MSN

1.76e-09343315252013
Pubmed

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.

EZR RDX MSN

1.76e-09343332160548
Pubmed

The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.

EZR RDX MSN

1.76e-09343312734202
Pubmed

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.

EZR RDX MSN

7.04e-09443312070130
Pubmed

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.

EZR RDX MSN

7.04e-09443327793041
Pubmed

The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

EZR RDX MSN

7.04e-09443315096511
Pubmed

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

EZR RDX MSN

7.04e-09443319890007
Pubmed

The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.

EZR RDX MSN

7.04e-09443328302370
Pubmed

Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.

EZR RDX MSN

7.04e-09443322685202
Pubmed

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.

EZR RDX MSN

7.04e-09443321289089
Pubmed

Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.

EZR RDX MSN

7.04e-09443317237445
Pubmed

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.

EZR RDX MSN

7.04e-09443321148287
Pubmed

Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.

EZR RDX MSN

7.04e-09443318941185
Pubmed

Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.

EZR RDX MSN

7.04e-09443315178693
Pubmed

Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.

EZR RDX MSN

7.04e-09443320660156
Pubmed

In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin.

EZR RDX MSN

7.04e-09443319129194
Pubmed

Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.

EZR RDX MSN

7.04e-09443315818415
Pubmed

Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.

EZR RDX MSN

7.04e-09443331018575
Pubmed

Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.

EZR RDX MSN

7.04e-09443324760896
Pubmed

Proteomic profiling in pancreatic cancer with and without lymph node metastasis.

EZR RDX MSN

7.04e-09443319152423
Pubmed

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.

EZR RDX MSN

7.04e-09443319255442
Pubmed

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.

EZR RDX MSN

7.04e-0944339890997
Pubmed

Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.

EZR RDX MSN

7.04e-09443320855527
Pubmed

Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.

EZR RDX MSN

1.76e-08543321278261
Pubmed

Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.

EZR RDX MSN

1.76e-08543322891241
Pubmed

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.

EZR RDX MSN

1.76e-08543310806479
Pubmed

Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.

EZR RDX MSN

1.76e-08543323019340
Pubmed

Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice.

EZR RDX MSN

1.76e-0854339464455
Pubmed

Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25.

EZR RDX MSN

1.76e-08543323326330
Pubmed

Regulation of NK cell trafficking by CD81.

EZR RDX MSN

1.76e-08543319830727
Pubmed

Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).

EZR RDX MSN

1.76e-08543325575591
Pubmed

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

EZR RDX MSN

1.76e-08543323063725
Pubmed

A novel role for BRCA1 in regulating breast cancer cell spreading and motility.

EZR RDX MSN

1.76e-08543321282464
Pubmed

Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells.

EZR RDX MSN

3.51e-08643317349711
Pubmed

Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.

EZR RDX MSN

3.51e-08643326209696
Pubmed

Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.

EZR RDX MSN

3.51e-08643317515952
Pubmed

Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice.

EZR RDX MSN

3.51e-08643323229862
Pubmed

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.

EZR RDX MSN

3.51e-0864339472040
Pubmed

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.

EZR RDX MSN

6.14e-08743323264465
Pubmed

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress.

EZR RDX MSN

6.14e-08743322291017
Pubmed

VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner.

EZR RDX MSN

9.82e-08843324788249
Pubmed

Finding the Unicorn, a New Mouse Model of Midfacial Clefting.

EZR RDX MSN

1.47e-07943331940751
Pubmed

The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.

PDPK2P PDPK1 SIRT1

1.47e-07943321775285
Pubmed

Radixin regulates cell migration and cell-cell adhesion through Rac1.

EZR RDX MSN

1.47e-07943322467863
Pubmed

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath.

EZR RDX MSN

3.84e-071243318579745
Pubmed

Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.

EZR RDX MSN

3.84e-071243329361573
Pubmed

Embryo-uterine interaction coordinates mouse embryogenesis during implantation.

EZR RDX MSN

4.99e-071343337522872
Pubmed

A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells.

EZR RDX MSN

4.99e-071343324135232
Pubmed

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.

EZR RDX MSN

6.35e-071443327641493
Pubmed

Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation.

EZR RDX MSN

1.18e-061743320706633
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

UBE2O MYO5A SNRNP200 PAICS ATAD2B HERC5 MSN FTSJ3

1.20e-0665343822586326
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

EZR PYM1 SNRNP200 HERC5 MSN

1.26e-0615243516009940
Pubmed

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland.

EZR RDX MSN

1.42e-061843331068622
Pubmed

The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development.

PDPK2P PDPK1

1.49e-06243215077109
Pubmed

Epinephrine-induced hyperpolarization of pancreatic islet cells is sensitive to PI3K-PDK1 signaling.

PDPK2P PDPK1

1.49e-06243219716369
Pubmed

PDK1 Is Required for Maintenance of CD4+ Foxp3+ Regulatory T Cell Function.

PDPK2P PDPK1

1.49e-06243233789982
Pubmed

Extracellular vesicle-derived circCEBPZOS attenuates postmyocardial infarction remodeling by promoting angiogenesis via the miR-1178-3p/PDPK1 axis.

PDPK2P PDPK1

1.49e-06243236726025
Pubmed

Expression of ezrin and moesin related to invasion, metastasis and prognosis of laryngeal squamous cell carcinoma.

EZR MSN

1.49e-06243225299115
Pubmed

Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin.

EZR MSN

1.49e-0624329213396
Pubmed

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta.

PDPK2P PDPK1

1.49e-06243210075713
Pubmed

Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice.

PDPK2P PDPK1

1.49e-06243217077298
Pubmed

3'Phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium.

PDPK2P PDPK1

1.49e-06243217077284
Pubmed

PDK1 regulates platelet activation and arterial thrombosis.

PDPK2P PDPK1

1.49e-06243223444402
Pubmed

Fine tuning PDK1 activity by phosphorylation at Ser163.

PDPK2P PDPK1

1.49e-06243216751192
Pubmed

α-SMA-Cre-mediated excision of PDK1 reveals an essential role of PDK1 in regulating morphology of cardiomyocyte and tumor progression in tissue microenvironment.

PDPK2P PDPK1

1.49e-06243225601552
Pubmed

Myosin Va is required for normal photoreceptor synaptic activity.

MYO5A MYO7A

1.49e-06243215316067
Pubmed

Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers.

EZR MSN

1.49e-06243212111362
Pubmed

PDK1 in NF-κB signaling is a target of Xanthium strumarium methanolic extract-mediated anti-inflammatory activities.

PDPK2P PDPK1

1.49e-06243227286918
Pubmed

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells.

PDPK2P PDPK1

1.49e-06243220944007
Pubmed

Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation.

PDPK2P PDPK1

1.49e-06243220051528
Pubmed

Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells.

PDPK2P PDPK1

1.49e-06243221063107
InteractionPLS3 interactions

EZR RDX UBE2O MYO5A PDPK1 MSN

1.05e-05237436int:PLS3
InteractionIMPA2 interactions

RDX PAICS HERC5 MSN

2.06e-0576434int:IMPA2
InteractionSIRT7 interactions

UBE2O MYO5A SNRNP200 PAICS SIRT1 ATAD2B HERC5 MSN FTSJ3

2.22e-05744439int:SIRT7
InteractionPDPK2P interactions

PDPK2P PDPK1

2.66e-054432int:PDPK2P
InteractionMYLK4 interactions

EZR RDX PAICS MSN

4.02e-0590434int:MYLK4
InteractionPHLPP2 interactions

EZR RDX UBE2O

4.30e-0532433int:PHLPP2
InteractionZRANB3 interactions

CUL2 HDGFL3 MSN

4.72e-0533433int:ZRANB3
InteractionCGAS interactions

MYO5A DDX60 CNP ATAD2B HERC5 FTSJ3

6.63e-05329436int:CGAS
InteractionISG15 interactions

EZR PYM1 MYO5A SNRNP200 HERC5 MSN FTSJ3

7.65e-05494437int:ISG15
InteractionMAP3K7 interactions

EZR RDX UBE2O PAICS PDPK1 MSN

1.46e-04380436int:MAP3K7
InteractionARHGEF15 interactions

EZR RDX MSN

1.56e-0449433int:ARHGEF15
InteractionCPNE4 interactions

RDX UBE2O FTSJ3

1.56e-0449433int:CPNE4
InteractionNPM1 interactions

ZBTB9 CUL2 RDX MYO5A SNRNP200 PAICS SIRT1 HERC5 MSN FTSJ3

1.71e-0412014310int:NPM1
Cytoband1p22.2

GBP3 GBP5

3.19e-04284321p22.2
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EZR RDX MYO7A MSN

6.27e-07502541293
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

EZR MYO7A

7.28e-0429252396
GeneFamilyPHD finger proteins

PHF1 KDM7A

6.82e-039025288
GeneFamilyActins|Deafness associated genes

RDX MYO7A

1.06e-021132521152
GeneFamilySolute carriers

SLC30A7 SLC18B1 SLCO2B1

1.67e-02395253752
CoexpressionBLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_UP

GBP3 KDM7A GBP5 DDX60 HERC5 AOX1

6.95e-06286436M34008
CoexpressionGSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP

GBP3 KDM7A GBP5 DDX60 HERC5

6.95e-06163435M8663
CoexpressionGSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP

GBP5 TYW5 DDX60 CNP HERC5

1.74e-05197435M9797
CoexpressionHOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_3DY_UP

GBP3 GBP5 DDX60 HERC5

4.35e-05119434M41109
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

GBP3 RNF216 GBP5 MYO5A MYO7A DOCK11 SNRNP200 EML3 RABGAP1L MSN

1.18e-0414924310M40023
CoexpressionHOWARD_DENDRITIC_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP3 GBP5 DDX60 HERC5

1.34e-04159434M40998
CoexpressionGSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN

GBP3 GBP5 DDX60 HERC5

1.37e-04160434M8664
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

GBP3 UBE2O PDPK2P MYO5A DDX60 PDPK1 SIRT1 AOX1 FTSJ3

1.39e-041226439MM979
CoexpressionGSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN

GBP3 GBP5 DDX60 CNP

1.89e-04174434M6769
CoexpressionNUYTTEN_NIPP1_TARGETS_UP

GBP3 GBP5 SLC18B1 DDX60 RABGAP1L HERC5 KCTD8

2.32e-04768437M6444
CoexpressionMCCLUNG_COCAIN_REWARD_4WK

PDPK2P PDPK1 SIRT1

2.66e-0476433MM682
CoexpressionGSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN

GBP5 DDX60 CNP HERC5

2.75e-04192434M4296
CoexpressionGSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN

GBP5 DDX60 CNP HERC5

2.92e-04195434M4292
CoexpressionGSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN

RDX GBP5 SIRT1 HERC5

2.98e-04196434M4231
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN

GBP5 DDX60 CNP HERC5

2.98e-04196434M4267
CoexpressionGSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN

GBP5 DDX60 CNP HERC5

3.04e-04197434M4294
CoexpressionLEE_BMP2_TARGETS_UP

EZR GBP3 KDM7A SLCO2B1 CNP RABGAP1L AOX1

3.09e-04805437MM1067
CoexpressionGSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN

SLC30A7 PLXND1 MYO5A SNRNP200

3.10e-04198434M6511
CoexpressionGSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN

KDM7A MYO7A SLC18B1 PDPK1

3.10e-04198434M7228
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN

GBP5 DDX60 CNP HERC5

3.10e-04198434M4264
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN

DDX60 CNP RABGAP1L HERC5

3.16e-04199434M4635
CoexpressionGSE14000_UNSTIM_VS_4H_LPS_DC_DN

GBP5 TYW5 CNP HERC5

3.16e-04199434M3347
CoexpressionGSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP

SLC30A7 KDM7A EML3 RABGAP1L

3.16e-04199434M5709
CoexpressionGSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP

CUL2 EXT2 KDM7A DDX60

3.22e-04200434M8042
CoexpressionGSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN

GBP3 DDX60 CNP HERC5

3.22e-04200434M3288
CoexpressionGSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP

PHF1 KDM7A SLCO2B1 MSN

3.22e-04200434M9737
CoexpressionGSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN

RDX PLXND1 MYO5A SNRNP200

3.22e-04200434M6513
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN

GBP5 DDX60 CNP HERC5

3.22e-04200434M4269
CoexpressionGSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP

PHF1 EZR DDX60 MSN

3.22e-04200434M7195
CoexpressionGSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN

RDX SOX21 PAICS EML3

3.22e-04200434M9791
CoexpressionGSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

RDX CYP4F3 KDM7A DOCK11

3.22e-04200434M9136
CoexpressionGSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP

PHF1 CYP4F3 KDM7A DDX60

3.22e-04200434M7430
CoexpressionBLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP

GBP3 GBP5 DDX60 HERC5

3.47e-04204434M34006
CoexpressionNAKAYA_PBMC_FLUAD_IMUVAC_MALE_AGE_14_27YO_CORRELATED_WITH_HAI_RESPONSE_MF59_ADJUVANTED_AND_NON_1DY_GENES_IN_BTM_M75_POSITIVE

DDX60 HERC5

4.42e-0419432M41012
CoexpressionHECKER_IFNB1_TARGETS

CYP4F3 DDX60 HERC5

5.12e-0495433M3010
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP3 GBP5 DDX60 CNP RABGAP1L HERC5

3.27e-08195436b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP3 GBP5 DDX60 CNP HERC5

7.18e-0717543597616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GBP3 GBP5 DDX60 CNP HERC5

1.02e-061884356f8946d4710f6e32c937213f99b790b098b8819c
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

GBP3 DDX60 CNP RABGAP1L HERC5

1.10e-061914352da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

GBP5 DDX60 CNP RABGAP1L HERC5

1.13e-061924351a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

PLXND1 MYO5A MYO7A SLC18B1 SLCO2B1

1.16e-0619343564d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GBP5 DDX60 HERC5 FTSJ3

1.79e-051624346ffcf369d954c20ce036aa1d072cee4e205f728e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GBP5 DDX60 HERC5 FTSJ3

1.79e-05162434bcbf7f80a2a1c80def795e345f16cf16e8b9d03b
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

PLXND1 MYO5A MYO7A SLCO2B1

1.97e-05166434be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP3 GBP5 DDX60 HERC5

2.16e-0517043407b561cd9c528bc8444c9385e1de621eee7b697e
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PYM1 MYO5A DOCK11 CNP

2.16e-051704343ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP3 DDX60 CNP HERC5

2.65e-05179434af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

GBP3 DDX60 RABGAP1L HERC5

2.89e-051834348f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DDX60 CNP RABGAP1L HERC5

2.89e-05183434dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP3 GBP5 DDX60 HERC5

3.01e-05185434f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GBP3 GBP5 RABGAP1L HERC5

3.14e-0518743472e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO5A MYO7A SLC18B1 SLCO2B1

3.14e-0518743439b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5A MYO7A SLC18B1 SLCO2B1

3.34e-05190434f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

PLXND1 MYO5A MYO7A SLCO2B1

3.55e-0519343431c0978ba78c9516d498aec0798902e57555e557
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 MYO5A DOCK11 SLCO2B1

3.63e-05194434c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MYO5A MYO7A SLC18B1 SLCO2B1

3.70e-051954344008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

MYO5A MYO7A SLC18B1 SLCO2B1

3.70e-05195434e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 MYO5A DOCK11 SLCO2B1

3.77e-05196434cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

GBP5 MYO5A DOCK11 SLCO2B1

3.77e-051964347026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

GBP5 DDX60 CNP HERC5

3.77e-05196434417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellMild-CD4+_T_activated|Mild / Disease group and Cell class

GBP5 DDX60 CNP HERC5

3.77e-05196434daa1c3322d81e649161e889e1d78451d2d425d09
ToppCellsevere-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GBP3 GBP5 DDX60 HERC5

3.85e-05197434c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

GBP3 GBP5 DDX60 HERC5

3.93e-051984344b078714c49e7befb7b113d72485e712236d35fa
ToppCellSevere-CD4+_T_Exhausted|World / Disease group and Cell class

MYO5A RABGAP1L IL21 MSN

4.00e-05199434467c34893dd7d1a8a1c101c966f034cc04b9bcbd
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

GBP5 DDX60 RABGAP1L HERC5

4.00e-051994349f5750212b887f92761ade33fc6e108cd5275297
ToppCellSevere-CD4+_T_Exhausted|Severe / Disease group and Cell class

MYO5A RABGAP1L IL21 MSN

4.00e-05199434dc6b0291714e2b9501c0796a63678bfb9d1b1052
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

GBP5 DDX60 RABGAP1L HERC5

4.00e-05199434c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

UBE2O MYO5A RABGAP1L HDGFL3

4.00e-05199434f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RDX GBP3 SLCO2B1 MSN

4.08e-052004342d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RDX GBP3 DDX60 HERC5

4.08e-0520043489821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellParenchyma_Control_(B.)-Immune-TX-MoAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MYO5A MYO7A SLC18B1 SLCO2B1

4.08e-05200434670ef1e68be0d2c6ea20ab4dea1d051a3cc89799
ToppCellEndothelial-F|World / shred on cell class and cell subclass (v4)

RDX GBP3 GBP5

3.25e-0413943332d3c5d35e6c4205711c3500d736fd108443e6b4
ToppCellIIH-CD4-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

GBP5 DDX60 HERC5

3.91e-04148433ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

GBP5 DDX60 HERC5

4.23e-04152433b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP5 DDX60 HERC5

4.23e-0415243318194f757d319958f26e5a91f56d89f25711236f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYP4F3 MYO5A DOCK11

4.23e-041524330652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR SOX21 AOX1

4.31e-0415343395b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CCDC81 EFCAB6 KCTD8

4.31e-04153433fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR SOX21 AOX1

4.31e-04153433b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CCDC81 EFCAB6 KCTD8

4.31e-041534332482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR SOX21 AOX1

4.31e-041534333ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

GBP5 RABGAP1L IL21

4.31e-04153433da1bff9928d8c61bb1c389d45fd897cfa4bed023
ToppCellPBMC-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

DDX60 RABGAP1L HERC5

4.56e-041564339b6c5bcac516a62bcc1f5be32ffa8c92735ef0bc
ToppCellfrontal_cortex-Non-neuronal-astrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR SOX21 AOX1

4.64e-04157433803af734d7f775d294391e2b84e472a732e18cef
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR SOX21 AOX1

4.64e-041574339aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR SOX21 AOX1

4.64e-041574330551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

4.73e-0415843366c011e9de002224f70725dfe8e7871c8d304492
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

GBP3 GBP5 HERC5

4.82e-0415943397c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

GBP3 GBP5 HERC5

4.82e-04159433fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5A SLCO2B1 DDX60

4.91e-0416043318954241e11309ecb0f3ca87897eadcb20dc8eca
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP5 DOCK11 KCTD8

5.00e-04161433bf70be1de418615b5442ec684552551edaf1f072
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP3 SLCO2B1 MSN

5.00e-04161433a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EZR CNP RABGAP1L

5.00e-0416143398be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EZR CNP RABGAP1L

5.00e-041614337af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP3 SLCO2B1 MSN

5.09e-041624330bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP3 SLCO2B1 MSN

5.09e-041624335799a602ef8d83925907e8e34532428be7330228
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLXND1 MYO5A SLCO2B1

5.18e-041634334b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP3 GBP5 HERC5

5.18e-04163433d005115aa1e1458b51de7eb719794617a4168608
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP3 SLCO2B1 MSN

5.27e-041644336a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP3 SLCO2B1 MSN

5.27e-04164433ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP3 SLCO2B1 MSN

5.46e-0416643327af6c906cff1d40d134f0386db7708869691121
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR MYO5A CNP

5.66e-04168433ce9fae8b295c668b0959d5007a8bcd401d80e258
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

5.66e-04168433784ce773521e5d74570f45120e56d112bc76ff49
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR CNP RABGAP1L

5.66e-04168433943687a33fffd7e19d906b9dd385a126bcea109a
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O MYO5A KCTD8

5.75e-04169433c5015ddb838849ea892a2cae5a739b554eb6d793
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP5 MYO5A SLCO2B1

5.85e-041704336ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCelldroplet-Fat-Gat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

5.85e-041704335185187ecf26b4c9eaa0c01ad52697ab8d075cc7
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

5.85e-041704337a4ed69c807c3761210776e8fe6680d1bd892e82
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CNP RABGAP1L

5.95e-04171433a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CNP RABGAP1L

5.95e-0417143343d8fd9b9546e84a652564fe96b514b34b06262b
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR MYO5A CNP

5.95e-04171433584a095ddcbf78aa29527f84b46b5ad3e2edbaa9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CUL2 GBP5 HERC5

6.06e-04172433eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A UBE2O DDX60

6.06e-04172433d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP5 MYO5A SLCO2B1

6.06e-04172433c96bd3407911df3e3e6d7a3dba786b11814b9598
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5A SLCO2B1 DDX60

6.06e-04172433714172f31abd0d25261df6115ec6a9df491fa14b
ToppCelldroplet-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

6.16e-04173433886ac1b98f709ad7131df778b83712bf8ed313de
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PYM1 GBP5 CNP

6.16e-04173433da0f1461643294f92e20b5e456a50211a2780a91
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP5 MYO5A HDGFL3

6.16e-04173433cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP5 MYO5A HDGFL3

6.16e-041734337456a417c5c1d4ba25f9489065aae322421308a6
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP5 MYO5A HDGFL3

6.16e-0417343335586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

6.26e-0417443328ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO5A DOCK11 SLCO2B1

6.26e-04174433d5c22b43531414951666ee7542a66ed9380e2d14
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP3 EXT2 SIRT1

6.26e-0417443355cc8300489d11322724159ec7d0e1d32a702e91
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

GBP5 DDX60 HERC5

6.37e-04175433ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

GBP5 DDX60 HERC5

6.37e-04175433ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

6.47e-04176433741fdacb33d49b030a797a6099fdea0949a22e75
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP5 SLCO2B1 MSN

6.47e-04176433eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR CNP RABGAP1L

6.58e-04177433c506b8fd9a550e6cf93b64a1f7eed2543224a140
ToppCellBAL-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

DDX60 RABGAP1L HERC5

6.58e-04177433aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR CNP RABGAP1L

6.58e-04177433840eaac045ada42cae0ab81177d1d0ae55a65633
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR CNP RABGAP1L

6.69e-041784338d74c12c4b0ce8bcb0f59151bdc67036997095ef
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EZR SOX21 EML3

6.69e-041784334813d6509738f088c12ebf395b70d496af04649a
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR CNP RABGAP1L

6.69e-041784338ef229f38aa8a2ae8b366c3ce26d4cb1302d674a
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EZR CNP RABGAP1L

6.69e-04178433525c4b3f9736ff206e2f1378c2a29ba4f13ba22f
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR CNP RABGAP1L

6.69e-041784339b932b677ae05ac6e12cd6ce97789f8c10e4790b
Diseasefeeling miserable measurement

ATAD2B RABGAP1L IL21

2.11e-0479433EFO_0009598
DiseaseLiver Cirrhosis, Experimental

EZR MYO5A SIRT1 CNP RABGAP1L MSN

8.52e-04774436C0023893
Diseaseunipolar depression, mood disorder

PHF1 ATAD2B RABGAP1L

9.90e-04134433EFO_0003761, EFO_0004247
DiseaseCeliac Disease

GBP5 IL21

2.15e-0347432C0007570
DiseaseOsteosarcoma

EXT2 SIRT1

2.15e-0347432C0029463
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

RDX MYO7A

2.53e-0351432cv:CN043650
DiseaseInfluenza

DDX60 HERC5

2.63e-0352432C0021400
Diseasealcohol use disorder (implicated_via_orthology)

PDPK2P PDPK1 SIRT1

2.89e-03195433DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PVTLKELLEFKFKYP

AOX1

246

Q06278
VIKPIDKKAPDFVFY

RDX

256

P35241
DFKKIHIPDYFPERK

KCTD8

446

Q6ZWB6
KRLKTPDLFKFPFFE

KDM7A

386

Q6ZMT4
VVFPLLYPEIFEKFK

ATAD2B

416

Q9ULI0
DVYFFDIPFPKIGKL

DDX60

1336

Q8IY21
DKPPLAVKYFFDFLE

PLXND1

1731

Q9Y4D7
VIKPIDKKAPDFVFY

MSN

256

P26038
KFFPKKKCFVFDLPI

GBP3

226

Q9H0R5
KFFPKKKCFIFDLPA

GBP5

226

Q96PP8
ENKYVKFFKSKPELP

PYM1

46

Q9BRP8
KIIKLEYDFPEKFFP

PDPK2P

266

Q6A1A2
FLGPKDLFPYKEYKD

HDGFL3

56

Q9Y3E1
FSPVPKDRDKFYFKL

RABGAP1L

291

Q5R372
FPVKPKFEKKRYFFF

HERC5

756

Q9UII4
PKDPKVLAEYKFEFL

DOCK11

1056

Q5JSL3
KFPELKFKYVEEEQP

DYM

621

Q7RTS9
DPAFKKRFLDFSKEP

EFCAB6

636

Q5THR3
EKPEFYKSFLFDKRP

CCDC81

401

Q6ZN84
DSYEKKPPKEFLERF

IL21

126

Q9HBE4
KKFPLKFYQEIFESP

CUL2

196

Q13617
KLKPGLEKDFLPLYF

CNP

176

P09543
AIVPKDKVFYSFLKP

CYP4F3

116

Q08477
YKKPKFIPCFVFLPD

EML3

456

Q32P44
VIKPIDKKAPDFVFY

EZR

256

P15311
CKKKYFDFDREILPF

PHF1

266

O43189
LLKKDKFAFPVPYGL

SOX21

86

Q9Y651
YSILGPFFPKEAEKK

SLC18B1

51

Q6NT16
FQKIIKLEYDFPEKF

PDPK1

291

O15530
KLEYDFPEKFFPKAR

PDPK1

296

O15530
LAPDKVDSKFFDPKF

FTSJ3

201

Q8IY81
YFRKDPRPFFKFAKE

SIRT1

301

Q96EB6
KLPKIDFFDYSKLTP

RNF216

351

Q9NWF9
KEGYKFYPPKVELFF

PAICS

116

P22234
FLKFPSDYLFKPPKI

UBE2DNL

51

Q8IWF7
AIPYFFFPKEMPKEK

SLCO2B1

291

O94956
YKDDFPEKLKSFPNI

EXT2

701

Q93063
FKKIEFQPPEAKKFF

UBE2O

941

Q9C0C9
IKDDEYKPPKFNLFG

SLC30A7

6

Q8NEW0
KIFYIKQEPFEPKEE

ZBTB9

281

Q96C00
KDFFKKFLYEPLPVE

SNRNP200

1711

O75643
PLLKGDIKFPEFFKE

TYW5

126

A2RUC4
IKPNDFKFPFTFDEK

MYO5A

661

Q9Y4I1
FEEDKSYFPSIPKLL

MYO7A

2046

Q13402