Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	actin cytoskeleton	DOCK5 HIP1 DST MYL9 ARHGEF5 SPTA1 ANKRD26 ACTN1 ACTN2 DIAPH3 MYL12B	3.30e-05	576	89	11	GO:0015629
GeneOntologyCellularComponent	Z disc	CACNA1C DST MYL9 ACTN1 ACTN2 MYL12B	4.56e-05	151	89	6	GO:0030018
GeneOntologyCellularComponent	I band	CACNA1C DST MYL9 ACTN1 ACTN2 MYL12B	7.72e-05	166	89	6	GO:0031674
GeneOntologyCellularComponent	Gtr1-Gtr2 GTPase complex	RRAGA RRAGB	1.07e-04	4	89	2	GO:1990131
GeneOntologyCellularComponent	actin filament bundle	DST MYL9 ACTN1 DIAPH3 MYL12B	1.50e-04	118	89	5	GO:0032432
GeneOntologyCellularComponent	glutamatergic synapse	CUL3 CACNA1C HIP1 DRP2 NETO1 PLXNC1 RNF10 PORCN ACTN1 ACTN2 FBXL20 RGS7	1.75e-04	817	89	12	GO:0098978
GeneOntologyCellularComponent	stereocilia coupling link	DIAPH3 USH2A	4.94e-04	8	89	2	GO:0002139
GeneOntologyCellularComponent	cortical actin cytoskeleton	HIP1 SPTA1 ACTN1 ACTN2	6.71e-04	93	89	4	GO:0030864
GeneOntologyCellularComponent	sarcomere	CACNA1C DST MYL9 ACTN1 ACTN2 MYL12B	6.85e-04	249	89	6	GO:0030017
GeneOntologyCellularComponent	GTPase complex	RRAGA RRAGB GNAT1	7.07e-04	41	89	3	GO:1905360
GeneOntologyCellularComponent	dense core granule membrane	VPS13C ACTN1	7.89e-04	10	89	2	GO:0032127
GeneOntologyCellularComponent	cell cortex	HIP1 DST MYL9 SPTA1 ACTN1 ACTN2 MYL12B	1.04e-03	371	89	7	GO:0005938
GeneOntologyCellularComponent	myofibril	CACNA1C DST MYL9 ACTN1 ACTN2 MYL12B	1.10e-03	273	89	6	GO:0030016
GeneOntologyCellularComponent	photoreceptor connecting cilium	GNAT1 TOPORS USH2A	1.12e-03	48	89	3	GO:0032391
GeneOntologyCellularComponent	contractile actin filament bundle	DST MYL9 ACTN1 MYL12B	1.13e-03	107	89	4	GO:0097517
GeneOntologyCellularComponent	stress fiber	DST MYL9 ACTN1 MYL12B	1.13e-03	107	89	4	GO:0001725
GeneOntologyCellularComponent	contractile muscle fiber	CACNA1C DST MYL9 ACTN1 ACTN2 MYL12B	1.50e-03	290	89	6	GO:0043292
GeneOntologyCellularComponent	actomyosin	DST MYL9 ACTN1 MYL12B	1.58e-03	117	89	4	GO:0042641
GeneOntologyCellularComponent	cortical cytoskeleton	HIP1 SPTA1 ACTN1 ACTN2	2.25e-03	129	89	4	GO:0030863
GeneOntologyCellularComponent	pseudopodium	ACTN1 ACTN2	2.62e-03	18	89	2	GO:0031143
GeneOntologyCellularComponent	cluster of actin-based cell projections	ACTN1 DIAPH3 CUBN USH2A MYL12B	2.65e-03	223	89	5	GO:0098862
GeneOntologyCellularComponent	platelet alpha granule lumen	SERPINE1 ACTN1 ACTN2	2.94e-03	67	89	3	GO:0031093
GeneOntologyCellularComponent	photoreceptor cell cilium	IMPG1 GNAT1 TOPORS USH2A	2.95e-03	139	89	4	GO:0097733
Domain	Spectrin	DST DRP2 SPTA1 ACTN1 ACTN2	6.15e-08	23	87	5	PF00435
Domain	Spectrin_repeat	DST DRP2 SPTA1 ACTN1 ACTN2	2.12e-07	29	87	5	IPR002017
Domain	Spectrin/alpha-actinin	DST DRP2 SPTA1 ACTN1 ACTN2	3.56e-07	32	87	5	IPR018159
Domain	SPEC	DST DRP2 SPTA1 ACTN1 ACTN2	3.56e-07	32	87	5	SM00150
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	3.89e-07	4	87	3	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A3 LRRC37A2	3.89e-07	4	87	3	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	3.89e-07	4	87	3	IPR029423
Domain	LRRC37	LRRC37A LRRC37A3 LRRC37A2	3.89e-07	4	87	3	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A3 LRRC37A2	3.89e-07	4	87	3	IPR015753
Domain	EF-hand-dom_pair	CACNA1C DST DRP2 MYL9 SPTA1 SPEF2 ACTN1 ACTN2 MYL10 MYL12B	8.85e-07	287	87	10	IPR011992
Domain	EF-hand_Ca_insen	SPTA1 ACTN1 ACTN2	1.93e-06	6	87	3	IPR014837
Domain	EFhand_Ca_insen	SPTA1 ACTN1 ACTN2	1.93e-06	6	87	3	PF08726
Domain	EFh	DST MYL9 SPTA1 ACTN1 ACTN2 MYL10 MYL12B	9.00e-06	158	87	7	SM00054
Domain	EF-hand_6	MYL9 MYL10 MYL12B	2.70e-05	13	87	3	PF13405
Domain	-	DST DRP2 MYL9 SPTA1 ACTN1 ACTN2 MYL10 MYL12B	2.94e-05	261	87	8	1.10.238.10
Domain	EF_HAND_2	DST MYL9 SPTA1 ACTN1 ACTN2 MYL10 MYL12B	1.02e-04	231	87	7	PS50222
Domain	EF_hand_dom	DST MYL9 SPTA1 ACTN1 ACTN2 MYL10 MYL12B	1.05e-04	232	87	7	IPR002048
Domain	SH3_1	DOCK5 DST PIK3R1 ARHGEF5 SPTA1 PPP1R13L	1.17e-04	164	87	6	PF00018
Domain	Ndr	NDRG3 NDRG4	1.28e-04	4	87	2	PF03096
Domain	Gtr1_RagA	RRAGA RRAGB	1.28e-04	4	87	2	PF04670
Domain	NDRG	NDRG3 NDRG4	1.28e-04	4	87	2	IPR004142
Domain	Gtr1_RagA	RRAGA RRAGB	1.28e-04	4	87	2	IPR006762
Domain	Actinin_actin-bd_CS	DST ACTN1 ACTN2	1.62e-04	23	87	3	IPR001589
Domain	ACTININ_2	DST ACTN1 ACTN2	1.62e-04	23	87	3	PS00020
Domain	ACTININ_1	DST ACTN1 ACTN2	1.62e-04	23	87	3	PS00019
Domain	CH	DST SPEF2 ACTN1 ACTN2	3.74e-04	73	87	4	PS50021
Domain	CH-domain	DST SPEF2 ACTN1 ACTN2	4.15e-04	75	87	4	IPR001715
Domain	SH3	DOCK5 DST PIK3R1 ARHGEF5 SPTA1 PPP1R13L	5.17e-04	216	87	6	PS50002
Domain	SH3_domain	DOCK5 DST PIK3R1 ARHGEF5 SPTA1 PPP1R13L	5.70e-04	220	87	6	IPR001452
Domain	EF-hand_1	DST MYL9 ACTN1 ACTN2 MYL12B	7.22e-04	152	87	5	PF00036
Domain	COMM	COMMD1 COMMD3	9.42e-04	10	87	2	IPR017920
Domain	COMM_domain	COMMD1 COMMD3	9.42e-04	10	87	2	PF07258
Domain	COMM	COMMD1 COMMD3	9.42e-04	10	87	2	PS51269
Domain	EF_Hand_1_Ca_BS	DST MYL9 ACTN1 MYL10 MYL12B	1.36e-03	175	87	5	IPR018247
Domain	-	PPT1 NDRG3 FAM135A NDRG4	2.32e-03	119	87	4	3.40.50.1820
Domain	AB_hydrolase	PPT1 NDRG3 FAM135A NDRG4	2.32e-03	119	87	4	IPR029058
Domain	EF_HAND_1	DST MYL9 ACTN1 MYL10 MYL12B	2.65e-03	204	87	5	PS00018
Domain	SH3	DOCK5 PIK3R1 ARHGEF5 SPTA1 PPP1R13L	3.39e-03	216	87	5	SM00326
Domain	CH	DST ACTN1 ACTN2	3.46e-03	65	87	3	SM00033
Domain	CH	DST ACTN1 ACTN2	4.27e-03	70	87	3	PF00307
Domain	-	DST ACTN1 ACTN2	4.44e-03	71	87	3	1.10.418.10
Domain	ARM-type_fold	DOCK5 HIP1 AOPEP UBR4 COPG2 DIAPH3	5.04e-03	339	87	6	IPR016024
Domain	RA	RASIP1 RAPH1	9.14e-03	31	87	2	SM00314
Pathway	REACTOME_RHO_GTPASE_CYCLE	CUL3 DOCK5 ARHGEF28 DST YKT6 PIK3R1 ARHGEF5 ANKRD26 ACTN1 DIAPH3 FAM135A	3.37e-06	439	63	11	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	CUL3 DOCK5 ARHGEF28 DST YKT6 PIK3R1 ARHGEF5 ANKRD26 ACTN1 DIAPH3 FAM135A	4.27e-06	450	63	11	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	CUL3 DOCK5 ARHGEF28 DST YKT6 MYL9 PIK3R1 ARHGEF5 ANKRD26 ACTN1 DIAPH3 MYL12B FAM135A	4.62e-06	649	63	13	MM15690
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_RHOA_SIGNALING_PATHWAY	MYL9 MYL10 MYL12B	9.98e-06	10	63	3	M47739
Pathway	KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	MYL9 PIK3R1 ACTN1 ACTN2 MYL10 MYL12B	1.26e-05	116	63	6	M2164
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY	MYL9 MYL10 MYL12B	1.37e-05	11	63	3	M47721
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	CUL3 DOCK5 ARHGEF28 DST YKT6 MYL9 PIK3R1 ARHGEF5 ANKRD26 ACTN1 DIAPH3 MYL12B FAM135A	1.41e-05	720	63	13	M41838
Pathway	REACTOME_RHOG_GTPASE_CYCLE	DOCK5 YKT6 PIK3R1 ARHGEF5 DIAPH3	1.57e-05	71	63	5	MM15604
Pathway	REACTOME_RHOG_GTPASE_CYCLE	DOCK5 YKT6 PIK3R1 ARHGEF5 DIAPH3	1.93e-05	74	63	5	M41814
Pathway	REACTOME_RND1_GTPASE_CYCLE	DST PIK3R1 ANKRD26 FAM135A	3.57e-05	42	63	4	M41828
Pathway	REACTOME_RND1_GTPASE_CYCLE	DST PIK3R1 ANKRD26 FAM135A	3.92e-05	43	63	4	MM15679
Pathway	KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	MYL9 PIK3R1 ACTN1 ACTN2 DIAPH3 MYL10 MYL12B	4.40e-05	213	63	7	M18306
Pathway	REACTOME_NEPHRIN_FAMILY_INTERACTIONS	PIK3R1 ACTN1 ACTN2	1.41e-04	23	63	3	M913
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ARHGEF28 PIK3R1 ARHGEF5 DIAPH3	2.52e-04	69	63	4	MM15596
Pathway	KEGG_FOCAL_ADHESION	MYL9 PIK3R1 ACTN1 ACTN2 MYL10 MYL12B	2.55e-04	199	63	6	M7253
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ARHGEF28 PIK3R1 ARHGEF5 DIAPH3	2.66e-04	70	63	4	M41806
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ARHGEF28 PIK3R1 ARHGEF5 DIAPH3	2.66e-04	70	63	4	MM15597
Pathway	KEGG_TIGHT_JUNCTION	MYL9 ACTN1 ACTN2 MYL10 MYL12B	3.03e-04	132	63	5	M11355
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ARHGEF28 PIK3R1 ARHGEF5 DIAPH3	3.30e-04	74	63	4	M41807
Pathway	REACTOME_RHOA_GTPASE_CYCLE	ARHGEF28 YKT6 PIK3R1 ARHGEF5 DIAPH3	4.25e-04	142	63	5	MM15576
Pathway	REACTOME_SMOOTH_MUSCLE_CONTRACTION	MYL9 MYL10 MYL12B	5.03e-04	35	63	3	MM15114
Pathway	REACTOME_RHOA_GTPASE_CYCLE	ARHGEF28 YKT6 PIK3R1 ARHGEF5 DIAPH3	5.29e-04	149	63	5	M41805
Pathway	REACTOME_RHOF_GTPASE_CYCLE	PIK3R1 ACTN1 DIAPH3	8.03e-04	41	63	3	MM15630
Pathway	REACTOME_MUSCLE_CONTRACTION	CACNA1C MYL9 ACTN2 MYL10 MYL12B	8.40e-04	165	63	5	MM15026
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST PIK3R1 ANKRD26	8.62e-04	42	63	3	M41826
Pathway	REACTOME_RHOF_GTPASE_CYCLE	PIK3R1 ACTN1 DIAPH3	8.62e-04	42	63	3	M41821
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST PIK3R1 ANKRD26	8.62e-04	42	63	3	MM15677
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST PIK3R1 ANKRD26	9.24e-04	43	63	3	M41827
Pathway	REACTOME_SMOOTH_MUSCLE_CONTRACTION	MYL9 MYL10 MYL12B	9.24e-04	43	63	3	M1429
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	CACNA1C ARHGEF28 DRP2 MYL9 PLXNC1 PIK3R1 SPTA1 SCD5 MYL12B	9.71e-04	575	63	9	M29853
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST PIK3R1 ANKRD26	9.89e-04	44	63	3	MM15678
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK5 YKT6 PIK3R1 ARHGEF5 DIAPH3	1.09e-03	175	63	5	MM15599
Pathway	BIOCARTA_CELL2CELL_PATHWAY	ACTN1 ACTN2	1.26e-03	12	63	2	M12851
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK5 YKT6 PIK3R1 ARHGEF5 DIAPH3	1.37e-03	184	63	5	M41809
Pathway	REACTOME_RHOD_GTPASE_CYCLE	PIK3R1 ACTN1 DIAPH3	1.70e-03	53	63	3	M41811
Pathway	BIOCARTA_UCALPAIN_PATHWAY	ACTN1 ACTN2	1.73e-03	14	63	2	M13143
Pathway	KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY	RRAGA RRAGB	1.73e-03	14	63	2	M47922
Pathway	KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY	RRAGA RRAGB	1.73e-03	14	63	2	M47918
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A3 LRRC37A2	6.47e-08	4	89	3	22419166
Pubmed	The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.	ALMS1 ACTN1 ACTN2	3.22e-07	6	89	3	22693585
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A3 LRRC37A2	1.92e-06	10	89	3	23064749
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CACNA1C DST RAPH1 SETD5 SPTA1 SPEF2 UBR4 ANKRD26 ACTN1 ACTN2 DIAPH3 EBNA1BP2 PEX11A TASOR2 LCMT1	3.65e-06	1442	89	15	35575683
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	DOCK5 DST YKT6 VPS13C ANKRD26 COPG2 EBNA1BP2 SMCR8 NDRG3 FAM135A TASOR2	4.84e-06	777	89	11	35844135
Pubmed	Regulation of class A scavenger receptor-mediated cell adhesion and surface localization by PI3K: identification of a regulatory cytoplasmic motif.	MSR1 PIK3R1	6.48e-06	2	89	2	19952357
Pubmed	NDRG3 and NDRG4, two novel tumor-related genes.	NDRG3 NDRG4	6.48e-06	2	89	2	23725756
Pubmed	Focused screening of a panel of cancer-related genetic polymorphisms reveals new susceptibility loci for pediatric acute lymphoblastic leukemia.	MSR1 PPP1R13L	6.48e-06	2	89	2	24604828
Pubmed	Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2.	ACTN1 ACTN2	6.48e-06	2	89	2	23664615
Pubmed	RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway.	RRAGA RRAGB	6.48e-06	2	89	2	9394008
Pubmed	Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases.	RRAGA RRAGB	6.48e-06	2	89	2	7499430
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	POMZP3 COMMD1 ALMS1 ANKRD26 COPG2 AASDHPPT EBNA1BP2 CUBN USH2A LCMT1	8.53e-06	670	89	10	22990118
Pubmed	Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.	MYL9 MYL10 MYL12B	8.86e-06	16	89	3	19794400
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	HIP1 DST YKT6 DENND5A SCD5 TOPORS FAM135A	8.95e-06	285	89	7	34369648
Pubmed	CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling.	CUL3 COMMD1 COMMD3	1.79e-05	20	89	3	23563313
Pubmed	COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.	CUL3 COMMD1 COMMD3	1.79e-05	20	89	3	21778237
Pubmed	Direct binding of alpha-actinin enhances TRPP3 channel activity.	ACTN1 ACTN2	1.94e-05	3	89	2	17944866
Pubmed	Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes.	ACTN1 ACTN2	1.94e-05	3	89	2	30768638
Pubmed	Metabolism. Differential regulation of mTORC1 by leucine and glutamine.	RRAGA RRAGB	1.94e-05	3	89	2	25567907
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	DST ACTN2	1.94e-05	3	89	2	19932097
Pubmed	The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism.	ACTN1 ACTN2	1.94e-05	3	89	2	11101506
Pubmed	KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity.	CUL3 PIK3R1	1.94e-05	3	89	2	33292627
Pubmed	The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm.	CACNA1C TMEM161B	1.94e-05	3	89	2	33597309
Pubmed	Interaction of PKN with alpha-actinin.	ACTN1 ACTN2	1.94e-05	3	89	2	9030526
Pubmed	Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells.	MYL9 MYL12B	1.94e-05	3	89	2	11942626
Pubmed	RagA, but not RagB, is essential for embryonic development and adult mice.	RRAGA RRAGB	1.94e-05	3	89	2	24768164
Pubmed	Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance.	RRAGA RRAGB	1.94e-05	3	89	2	31649036
Pubmed	Rag GTPases are cardioprotective by regulating lysosomal function.	RRAGA RRAGB	1.94e-05	3	89	2	24980141
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	CUL3 DOCK5 KBTBD3 MYL9 BTNL3 VPS13C UCHL5 MED14 AASDHPPT EBNA1BP2	2.35e-05	754	89	10	35906200
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	MYL9 UBR4 COPG2 ACTN1 EBNA1BP2 MYL12B	3.25e-05	235	89	6	28378594
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CUL3 HIP1 DST UCHL5 UBR4 ACTN1 TOPORS MYL12B	3.35e-05	481	89	8	28190767
Pubmed	Differential expression patterns of NDRG family proteins in the central nervous system.	NDRG3 NDRG4	3.87e-05	4	89	2	17998568
Pubmed	Inhibition of PDGF-B induction and cell growth by syndecan-1 involves the ubiquitin and SUMO-1 ligase, Topors.	SCD5 TOPORS	3.87e-05	4	89	2	22912899
Pubmed	Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart.	NDRG3 NDRG4	3.87e-05	4	89	2	11352569
Pubmed	Stable membrane expression of postsynaptic CaV1.2 calcium channel clusters is independent of interactions with AKAP79/150 and PDZ proteins.	CACNA1C ACTN1	3.87e-05	4	89	2	19091974
Pubmed	Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.	ACTN1 ACTN2	3.87e-05	4	89	2	1629252
Pubmed	YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.	RRAGA RRAGB	3.87e-05	4	89	2	33373332
Pubmed	Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.	CACNA1C ACTN2	3.87e-05	4	89	2	17110593
Pubmed	Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.	ACTN1 ACTN2	3.87e-05	4	89	2	16807302
Pubmed	Titin mutations as the molecular basis for dilated cardiomyopathy.	ACTN1 ACTN2	3.87e-05	4	89	2	11846417
Pubmed	ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.	ACTN1 ACTN2	3.87e-05	4	89	2	12446711
Pubmed	Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family.	NDRG3 NDRG4	3.87e-05	4	89	2	11936845
Pubmed	Molecular structure of the sarcomeric Z-disk: two types of titin interactions lead to an asymmetrical sorting of alpha-actinin.	ACTN1 ACTN2	3.87e-05	4	89	2	9501083
Pubmed	Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular motor.	MYL9 MYL12B	3.87e-05	4	89	2	24825904
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	DST YKT6 RRAGA PIK3R1 VPS13C SCD5 SMCR8 FAM135A	4.65e-05	504	89	8	34432599
Pubmed	Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.	ACTN1 ACTN2	6.44e-05	5	89	2	15665106
Pubmed	Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.	ACTN1 ACTN2	6.44e-05	5	89	2	15841212
Pubmed	The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.	ACTN1 ACTN2	6.44e-05	5	89	2	12837758
Pubmed	Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.	ACTN1 ACTN2	6.44e-05	5	89	2	19943616
Pubmed	IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse chromosome 5.	HIP1 POMZP3	6.44e-05	5	89	2	9434941
Pubmed	SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.	RRAGA RRAGB	6.44e-05	5	89	2	22575674
Pubmed	Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.	ACTN1 ACTN2	9.65e-05	6	89	2	18425115
Pubmed	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.	RRAGA RRAGB	9.65e-05	6	89	2	14660641
Pubmed	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.	RRAGA RRAGB	9.65e-05	6	89	2	11073942
Pubmed	Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.	RRAGA RRAGB	9.65e-05	6	89	2	24529380
Pubmed	Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models.	ALMS1 GNAT1	9.65e-05	6	89	2	37252956
Pubmed	Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling.	CUL3 GOLGA1	9.65e-05	6	89	2	30481304
Pubmed	Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia.	PIK3R1 SPTA1	9.65e-05	6	89	2	10187839
Pubmed	Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.	RRAGA RRAGB	9.65e-05	6	89	2	24081491
Pubmed	The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.	RRAGA RRAGB	9.65e-05	6	89	2	18497260
Pubmed	Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages.	MSR1 PIK3R1	9.65e-05	6	89	2	15006698
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	DST ALMS1 RAPH1 ZSCAN4 UBR4 COPG2 DIAPH3	1.02e-04	418	89	7	34709266
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	DOCK5 YKT6 PLXNC1 ANKRD26 DIAPH3 GNAT1 NDRG3 FAM135A	1.08e-04	569	89	8	30639242
Pubmed	Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.	HIP1 POMZP3 SERPINE1	1.28e-04	38	89	3	11779826
Pubmed	Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.	RRAGA RRAGB	1.35e-04	7	89	2	25259925
Pubmed	Temporal and spatial expression pattern of beta1 sodium channel subunit during heart development.	ACTN1 ACTN2	1.35e-04	7	89	2	15721864
Pubmed	Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.	ACTN1 ACTN2	1.35e-04	7	89	2	11724819
Pubmed	Genes for the CPE receptor (CPETR1) and the human homolog of RVP1 (CPETR2) are localized within the Williams-Beuren syndrome deletion.	HIP1 POMZP3	1.35e-04	7	89	2	9878248
Pubmed	Characterization and expression pattern of the frizzled gene Fzd9, the mouse homolog of FZD9 which is deleted in Williams-Beuren syndrome.	HIP1 POMZP3	1.35e-04	7	89	2	10198163
Pubmed	Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.	MYL9 MYL12B	1.35e-04	7	89	2	21126233
Pubmed	An Unbiased Proteomics Method to Assess the Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes.	ACTN1 ACTN2	1.35e-04	7	89	2	31573406
Pubmed	NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/β-catenin signaling.	NDRG3 NDRG4	1.35e-04	7	89	2	23068607
Pubmed	Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis.	MYL9 MYL12B	1.35e-04	7	89	2	8207020
Pubmed	KCTD7 mutations impair the trafficking of lysosomal enzymes through CLN5 accumulation to cause neuronal ceroid lipofuscinoses.	CUL3 PPT1	1.35e-04	7	89	2	35921411
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DST YKT6 ALMS1 RAPH1 ATAD5 ANKRD26 COPG2 AASDHPPT EBNA1BP2 SMCR8	1.39e-04	934	89	10	33916271
Pubmed	Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.	RRAGA RRAGB	1.79e-04	8	89	2	22980980
Pubmed	Mice deficient in alpha-actinin-4 have severe glomerular disease.	ACTN1 ACTN2	1.79e-04	8	89	2	12782671
Pubmed	Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.	RASIP1 CUBN	1.79e-04	8	89	2	25147783
Pubmed	CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.	ACTN1 ACTN2	1.79e-04	8	89	2	20215401
Pubmed	Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.	RRAGA RRAGB	1.79e-04	8	89	2	26582740
Pubmed	Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.	MYL9 MYL12B	1.79e-04	8	89	2	33424621
Pubmed	Arg/Abl-binding protein, a Z-body and Z-band protein, binds sarcomeric, costameric, and signaling molecules.	SPTA1 ACTN1	1.79e-04	8	89	2	20886612
Pubmed	Mapping of transcription start sites of human retina expressed genes.	IMPG1 CLUL1 GNAT1	2.13e-04	45	89	3	17286855
Pubmed	Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.	CUL3 PIK3R1	2.30e-04	9	89	2	27708159
Pubmed	Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.	ACTN1 ACTN2	2.30e-04	9	89	2	11114196
Pubmed	Two-hybrid system screen with the small GTP-binding protein Rab6. Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6.	DENND5A TASOR2	2.30e-04	9	89	2	7782346
Pubmed	Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.	RRAGA RRAGB	2.30e-04	9	89	2	24337580
Pubmed	p62 is a key regulator of nutrient sensing in the mTORC1 pathway.	RRAGA RRAGB	2.30e-04	9	89	2	21981924
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL3 DOCK5 ARHGEF28 DST CDC40 ARHGEF5 DENND5A RIOK2	2.67e-04	650	89	8	38777146
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	SPTA1 ACTN1	2.88e-04	10	89	2	1991513
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	ACTN1 ACTN2	2.88e-04	10	89	2	20368620
Pubmed	Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.	RRAGA RRAGB	2.88e-04	10	89	2	22424946
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CUL3 NAGK RAPH1 ABCA13 UBR4 PPP1R13L	3.38e-04	361	89	6	26167880
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	ALMS1 PPT1 PIK3R1 GNAT1 USH2A	3.40e-04	233	89	5	32290105
Pubmed	Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.	ACTN1 ACTN2	3.51e-04	11	89	2	11842093
Pubmed	Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.	RRAGA RRAGB	3.51e-04	11	89	2	25567906
Pubmed	Reprogramming tumour-associated macrophages to outcompete cancer cells.	RRAGA RRAGB	3.51e-04	11	89	2	37380769
Pubmed	Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.	RASIP1 ALMS1	3.51e-04	11	89	2	24586186
Pubmed	Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND.	MYL9 MYL12B	3.51e-04	11	89	2	9171826
Pubmed	A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.	RRAGA RRAGB	3.51e-04	11	89	2	23723238
Interaction	EBAG9 interactions	DST YKT6 PIK3R1 ANKRD26 COPG2 ACTN1 DIAPH3 SMCR8 FAM135A	5.82e-06	303	86	9	int:EBAG9
Interaction	GOLGA1 interactions	DST ALMS1 UBR4 ANKRD26 DIAPH3 SMCR8 GOLGA1	1.33e-05	183	86	7	int:GOLGA1
GeneFamily	Myosin light chains\|EF-hand domain containing	MYL9 MYL10 MYL12B	7.09e-06	14	50	3	657
GeneFamily	Actinins	ACTN1 ACTN2	4.48e-05	4	50	2	1112
GeneFamily	COMM domain containing	COMMD1 COMMD3	3.33e-04	10	50	2	979
GeneFamily	EF-hand domain containing	DST MYL9 SPTA1 MYL10 MYL12B	3.39e-04	219	50	5	863
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND5A SMCR8	2.16e-03	25	50	2	504
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP	MSR1 DOCK5 PLXNC1 UBR4 ENPP4 MYL12B LCMT1	5.10e-06	200	88	7	M9455
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 WNT9A YIPF7 ACTN2 SCD5 NDRG4	1.51e-06	177	89	6	7ebdcedfe02da6d05bba3d625d8bd4c4ea96e4ad
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST MYL9 WNT9A GPC5 DIAPH3 SCD5	1.95e-06	185	89	6	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST MYL9 WNT9A GPC5 DIAPH3 SCD5	2.08e-06	187	89	6	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	DST MYL9 WNT9A GPC5 DIAPH3 SCD5	2.21e-06	189	89	6	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK5 DST WNT9A GPC5 DIAPH3 SCD5	2.81e-06	197	89	6	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C MYL9 CCDC3 SERPINE1 ACTN1 ACTN2	3.06e-06	200	89	6	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 WNT9A YIPF7 ACTN2 NDRG4	2.08e-05	166	89	5	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 WNT9A YIPF7 ACTN2 NDRG4	2.08e-05	166	89	5	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSR1 ZBTB38 GVINP1 SPTA1 DIAPH3	2.27e-05	169	89	5	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	CACNA1C HIP1 MYL9 CCDC3 ACTN1	2.40e-05	171	89	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 YIPF7 ACTN2 SCD5 NDRG4	2.83e-05	177	89	5	c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYL9 WNT9A GPC5 DIAPH3 SCD5	2.99e-05	179	89	5	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA1C HIP1 MYL9 CCDC3 ACTN1	2.99e-05	179	89	5	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	368C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 RASIP1 PORCN ENPP4 CUBN	3.07e-05	180	89	5	eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell	368C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 RASIP1 PORCN ENPP4 CUBN	3.07e-05	180	89	5	ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	CACNA1C MYL9 CCDC3 ACTN1 ACTN2	3.07e-05	180	89	5	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	severe-CD8+_T_naive\|severe / disease stage, cell group and cell class	SPEF2 LRRC37A2 ANKRD26 ACTN1 FBXL20	3.07e-05	180	89	5	94fe530367b170777f4051a4034cff06d80dbb83
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 CCDC3 GPC5 CUBN USH2A	3.15e-05	181	89	5	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	CACNA1C MYL9 NETO1 SERPINE1 MYL10	3.15e-05	181	89	5	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	CACNA1C HIP1 ARHGEF28 CCDC3 ACTN1	3.32e-05	183	89	5	818fd886e0188091310825f9145fa53328f2c979
ToppCell	droplet-Lung-nan-21m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL9 CCDC3 WNT9A CUBN NDRG4	3.32e-05	183	89	5	b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCell	droplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL9 CCDC3 WNT9A CUBN NDRG4	3.32e-05	183	89	5	19e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DRP2 MYL9 WNT9A ACTN1 MYL10	3.32e-05	183	89	5	61a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C HIP1 ARHGEF28 CCDC3 ACTN1	3.32e-05	183	89	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST MYL9 GPC5 DIAPH3 SCD5	3.40e-05	184	89	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST MYL9 GPC5 DIAPH3 SCD5	3.40e-05	184	89	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL9 YIPF7 ACTN2 SCD5 NDRG4	3.49e-05	185	89	5	9ef66bf63ed728cbf3044520a2a1625a9d5863a4
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C AOPEP WNT9A SERPINE1 ACTN1	3.49e-05	185	89	5	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASIP1 MYL9 PLXNC1 ARHGEF5 PPP1R13L	3.49e-05	185	89	5	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL9 YIPF7 ACTN2 SCD5 NDRG4	3.49e-05	185	89	5	2148b78db2afaf29b01d604d314d6061179e2663
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 DST GPC5 DIAPH3 FAM135A	3.68e-05	187	89	5	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C DST MYL9 AOPEP ACTN1	3.68e-05	187	89	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 DST GPC5 DIAPH3 FAM135A	3.68e-05	187	89	5	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 DST GPC5 DIAPH3 FAM135A	3.68e-05	187	89	5	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	DST WNT9A GPC5 DIAPH3 SCD5	3.68e-05	187	89	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C MYL9 CCDC3 WNT9A ACTN1	3.77e-05	188	89	5	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYL9 CCDC3 WNT9A CUBN NDRG4	3.87e-05	189	89	5	cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYL9 CCDC3 WNT9A CUBN NDRG4	3.87e-05	189	89	5	102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	MSR1 ARHGEF28 PPT1 ACTN1 DENND5A	3.87e-05	189	89	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HIP1 ARHGEF28 CCDC3 SERPINE1 ACTN1	3.87e-05	189	89	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYL9 CCDC3 WNT9A CUBN NDRG4	3.87e-05	189	89	5	6e83bf855d4771885b60bb8992df2f9b508eef97
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	DOCK5 HIP1 MYL9 RRAGA ARHGEF5	3.97e-05	190	89	5	58a6ab70737d719ca9725ac087f20dfe9be0463e
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASIP1 MYL9 PLXNC1 TMEM132E CCDC3	4.27e-05	193	89	5	2483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 HIP1 DST ARHGEF5 LRRC37A2	4.38e-05	194	89	5	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 HIP1 DST ARHGEF5 LRRC37A2	4.38e-05	194	89	5	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DST WNT9A GPC5 DIAPH3 SCD5	4.49e-05	195	89	5	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C DST PIK3R1 CCDC3 ACTN1	4.60e-05	196	89	5	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C DST PIK3R1 CCDC3 ACTN1	4.60e-05	196	89	5	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C MYL9 CCDC3 ACTN1 ACTN2	4.60e-05	196	89	5	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C MYL9 CCDC3 SERPINE1 ACTN1	4.71e-05	197	89	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C MYL9 CCDC3 SERPINE1 ACTN1	4.71e-05	197	89	5	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYL9 AOPEP CCDC3 ACTN1 ACTN2	4.71e-05	197	89	5	71367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYL9 AOPEP CCDC3 ACTN1 ACTN2	4.71e-05	197	89	5	0f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYL9 AOPEP CCDC3 ACTN1 ACTN2	4.83e-05	198	89	5	e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASIP1 HIP1 CCDC3 SERPINE1 NDRG4	4.83e-05	198	89	5	58508a8df2714d769f137794c29441a7bd38b350
ToppCell	CTRL-Myeloid\|CTRL / Disease state, Lineage and Cell class	MSR1 DST PPT1 ACTN1 DENND5A	4.94e-05	199	89	5	70b89a930709fdb91fde6f96106add8455b11618
ToppCell	Mild-Myeloid-Macrophages-FCN1+SPP1+\|Mild / Condition, Lineage, Cell class and cell subclass	MSR1 NAGK DST PPT1 ACTN1	4.94e-05	199	89	5	2cbaef86af870a228cb46895dd765ea8894c83c5
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C DST MYL9 SERPINE1 ACTN1	4.94e-05	199	89	5	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	368C-Fibroblasts-Fibroblast-I\|368C / Donor, Lineage, Cell class and subclass (all cells)	AOPEP CCDC3 SERPINE1 EBNA1BP2 PPP1R13L	5.06e-05	200	89	5	70318b87a05e97ba2ea2539ac2f7d7dc593fca60
ToppCell	368C-Fibroblasts-Fibroblast-I-\|368C / Donor, Lineage, Cell class and subclass (all cells)	AOPEP CCDC3 SERPINE1 EBNA1BP2 PPP1R13L	5.06e-05	200	89	5	46de1ac3104e66e648d9843da6389ac8fa622ba2
ToppCell	RV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CACNA1C NAGK ACTN2 NDRG4	1.05e-04	122	89	4	1cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTA1 CCDC3 PEX11A PPP1R13L	1.51e-04	134	89	4	64979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SERPINE1 GPC5 DIAPH3 CUBN	1.74e-04	139	89	4	2fb51abb3ce88c21726c026d6365b2582e2e79f6
ToppCell	Lymphoid-Lymphoid-NK_cells\|Lymphoid / shred on cell class and cell subclass (v4)	GVINP1 CD226 ARHGEF5 ENPP4	2.21e-04	148	89	4	d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell	AT1-AT2_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	MYL9 AOPEP YIPF7 FAM135A	2.63e-04	155	89	4	010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	ZBTB38 RRAGA SPEF2 TOPORS	2.63e-04	155	89	4	9d53caee196b5c2bbc90c4f54f693b64d4086065
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB38 MYL9 PIK3R1 NDRG4	2.63e-04	155	89	4	08295584395e8d9cfc1b1648f98754b3ac53e587
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSR1 DOCK5 HIP1 PLXNC1	2.70e-04	156	89	4	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 SPTA1 SERPINE1 RNF10	2.83e-04	158	89	4	9fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 SPTA1 SERPINE1 RNF10	2.83e-04	158	89	4	0edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD226 PIK3R1 SCD5 NDRG4	2.97e-04	160	89	4	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	CACNA1C HIP1 CCDC3 ACTN1	3.04e-04	161	89	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	AT1_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	MYL9 GPC5 DIAPH3 SCD5	3.12e-04	162	89	4	ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C HIP1 CCDC3 ACTN1	3.34e-04	165	89	4	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C MYL9 BTNL3 ACTN2	3.34e-04	165	89	4	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 YIPF7 ACTN2 SCD5	3.50e-04	167	89	4	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	Control-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	DOCK5 HIP1 DST DENND5A	3.58e-04	168	89	4	d7118d39253ed9790908b850088ebfc5a86f4065
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 WNT9A YIPF7 RRAGB	3.66e-04	169	89	4	88aa2246ede582c2e11de63228d76f520889ecb3
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 WNT9A YIPF7 RRAGB	3.66e-04	169	89	4	a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYL9 WNT9A YIPF7 RRAGB	3.66e-04	169	89	4	42a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SPTA1 CUBN USH2A	3.66e-04	169	89	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	DST SERPINE1 GPC5 SCD5	3.74e-04	170	89	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	facs-Marrow-T-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSR1 RAPH1 CD226 VPS13C	3.74e-04	170	89	4	a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGEF28 ZSCAN4 MYL10 LCMT1	3.74e-04	170	89	4	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	facs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSR1 RAPH1 CD226 VPS13C	3.74e-04	170	89	4	ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCell	facs-GAT-Fat-18m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD226 RRAGB ACTN2 MYL10	3.91e-04	172	89	4	17a486c5d0430abb133eab9f087e2ef8b60f7d25
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	CACNA1C MYL9 CCDC3 ACTN1	4.00e-04	173	89	4	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C CCDC3 ACTN1 ACTN2	4.00e-04	173	89	4	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	TMEM161B FBXL20 PPP1R13L EDRF1	4.00e-04	173	89	4	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	ASK452-Immune-B_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	POMZP3 LRRC37A3 ATAD5 LRRC37A2	4.08e-04	174	89	4	69723f5666abc3af5f0431901a60246c9915ef81
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	DST GPC5 DIAPH3 SCD5	4.08e-04	174	89	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C MYL9 CCDC3 ACTN1	4.17e-04	175	89	4	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C TMEM161B FBXL20 FAM135A	4.36e-04	177	89	4	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPT1 PORCN ZNF225 COMMD3	4.36e-04	177	89	4	34458f1eb7f3b1fd0cb9904529c01a9ca2f15500
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-osteoclast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RAPH1 ACTN2 SCD5 NDRG4	4.45e-04	178	89	4	a28683690ab8a60eb18f3ef87ea85da4e95b22df
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGEF28 TMEM132E RGS7 NDRG4	4.54e-04	179	89	4	228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYL9 GPC5 SCD5 FAM135A	4.54e-04	179	89	4	d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYL9 CCDC3 ACTN1	4.64e-04	180	89	4	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	AT1_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	DST MYL9 DIAPH3 SCD5	4.64e-04	180	89	4	e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYL9 CCDC3 ACTN1	4.64e-04	180	89	4	f29a995cf6e1a1836ed68b73258d9370bf3d4434
Disease	pentachlorophenol measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022071
Disease	parathion measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022070
Disease	potassium chromate measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022072
Disease	mercuric chloride measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022068
Disease	heptachlor epoxide measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022067
Disease	methoxychlor measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022052
Disease	azinphos methyl measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022055
Disease	aldrin measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022054
Disease	dicofol measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022060
Disease	disulfoton measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022062
Disease	dieldrin measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022061
Disease	endrin measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022064
Disease	endosulfan measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022063
Disease	heptachlor measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022066
Disease	ethion measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022065
Disease	chlorpyrifos measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022057
Disease	cadmium chloride measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022056
Disease	diazinon measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022059
Disease	dibutyl phthalate measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0022058
Disease	environmental exposure measurement	COMMD1 DCAF8L1 USH2A RGS7	5.46e-05	73	83	4	EFO_0008360
Disease	DDT metabolite measurement	COMMD1 DCAF8L1 USH2A RGS7	5.76e-05	74	83	4	EFO_0007886
Disease	neurilemmoma (is_marker_for)	ATAD5 SERPINE1	7.77e-05	5	83	2	DOID:3192 (is_marker_for)
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN1 ACTN2	7.77e-05	5	83	2	DOID:0111128 (implicated_via_orthology)
Disease	vitamin B12 measurement	RASIP1 CUBN RGS7	1.00e-04	32	83	3	EFO_0004620
Disease	cerebrospinal fluid clusterin measurement	DST SETD5 ABCA13	1.32e-04	35	83	3	EFO_0007657
Disease	urinary albumin to creatinine ratio	RASIP1 RAPH1 AOPEP CUBN FBXL20	1.54e-04	179	83	5	EFO_0007778
Disease	blood cobalt measurement	COMMD1 DCAF8L1 USH2A RGS7	1.93e-04	101	83	4	EFO_0007577
Disease	Sudden Cardiac Death	CACNA1C PPP1R13L	2.16e-04	8	83	2	C0085298
Disease	Disorder of eye	ALMS1 PPT1 GNAT1 TOPORS USH2A	3.36e-04	212	83	5	C0015397
Disease	schizophrenia, anorexia nervosa	CUL3 CACNA1C ALMS1	3.39e-04	48	83	3	MONDO_0005090, MONDO_0005351
Disease	blood nickel measurement	COMMD1 DCAF8L1 USH2A RGS7	3.73e-04	120	83	4	EFO_0007583
Disease	N-acetylhistidine measurement	ALMS1 SERPINE1	4.23e-04	11	83	2	EFO_0800022
Disease	acute graft vs. host disease	MSR1 CUL3 ZBTB38	4.80e-04	54	83	3	EFO_0004599
Disease	breast carcinoma	ZBTB38 ARHGEF28 PLXNC1 ATAD5 AOPEP PIK3R1 ARHGEF5 ANKRD26 GPC5 TASOR2	5.73e-04	1019	83	10	EFO_0000305
Disease	glucose measurement	ZBTB38 YKT6 LRRC37A LRRC37A3 VPS13C SCD5	7.19e-04	380	83	6	EFO_0004468
Disease	1-Methylhistidine measurement	ALMS1 FBXL20	1.03e-03	17	83	2	EFO_0021543
Disease	wellbeing measurement, alcohol consumption measurement	DST CCDC3 USH2A	1.20e-03	74	83	3	EFO_0007869, EFO_0007878
Disease	alpha-tocopherol measurement	GPC5 USH2A	1.44e-03	20	83	2	EFO_0007898
Disease	CCL24 measurement	HIP1 POMZP3	1.74e-03	22	83	2	EFO_0009418
Disease	mean platelet volume	DOCK5 RASIP1 ZBTB38 CD226 ATAD5 RRAGA SPTA1 ACTN1 FBXL20	2.27e-03	1020	83	9	EFO_0004584
Disease	alcohol use disorder measurement, alcohol consumption measurement	CACNA1C RASIP1 FBXL20	2.62e-03	97	83	3	EFO_0007878, EFO_0009458
Disease	Nephrotic Syndrome	SERPINE1 GPC5	2.62e-03	27	83	2	C0027726
Disease	glucose tolerance test	VPS13C PEX11A	2.62e-03	27	83	2	EFO_0004307
Disease	reticulocyte count	DOCK5 ARHGEF28 CD226 PIK3R1 SPTA1 RNF10 ACTN1 SCD5 FBXL20	2.67e-03	1045	83	9	EFO_0007986

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTEFQMRNVDFLYSN	ATAD5	1496	Q96QE3
TSAEAMEVRFFRNQF	BTNL3	46	Q6UXE8
QRQFTILNFNDLMSS	AASDHPPT	266	Q9NRN7
EQMNEFRASFNHFDR	ACTN1	746	P12814
TQEQMNEFRASFNHF	ACTN2	751	P35609
RTFQSLMNSNSNFRE	ARHGEF5	1276	Q12774
LMNENFIFSFRNTQE	GVINP1	1726	Q7Z2Y8
LDAASKARMNSEFNF	ALMS1	3071	Q8TCU4
IFNFLELQAQSFMST	ABCA13	1036	Q86UQ4
NARTFSSEMEYNDFA	AOPEP	86	Q8N6M6
LEQFRENNFASMKSQ	ANKRD26	1511	Q9UPS8
DFLTDLNNFRTTFMQ	DIAPH3	996	Q9NSV4
REIQAQNFFSSFTLM	NAGK	291	Q9UJ70
FFFSNASLLNSLMER	RASIP1	776	Q5U651
LRQETNMANFSYRFS	RAPH1	56	Q70E73
RNSRFQMLFTSFQEP	NETO1	276	Q8TDF5
NVEMFFQLSSFLQVS	KBTBD3	121	Q8NAB2
FINEALVQMSFNTFN	ARHGEF28	1566	Q8N1W1
FNAFFNFEDMQEITQ	NDRG3	71	Q9UGV2
TTARNAFEENVFMEN	LRRC37A3	1391	O60309
SSMRKFQEQNETFQA	GOLGA1	101	Q92805
TTARNAFEENDFMEN	LRRC37A2	1391	A6NM11
TTARNAFEENDFMEN	LRRC37A	1391	A6NMS7
IETQFSFKDLNFRMF	GNAT1	181	P11488
RNMALEAAASVQEFF	GPC5	131	P78333
LERVAFAEFQMTSQN	EDRF1	1081	Q3B7T1
FFSLRVANMAFSNDL	IMPG1	576	Q17R60
FQNTIREMFSQFAEF	DST	5176	Q03001
DFQREMSFYRQAQAA	EBNA1BP2	101	Q99848
DFLMSERNQNDTFAD	FAM135A	1281	Q9P2D6
ERNQNDTFADFDSMT	FAM135A	1286	Q9P2D6
QRATSNVFAMFDQSQ	MYL9	16	P24844
AQAFMDAFSLTEQQL	PLXNC1	1446	O60486
SSVFSMFDQTQIQEF	MYLPF	16	Q96A32
SDSQELQTFLFMLFF	OR4F5	11	Q8NH21
FMNYNSSVSFEERLN	ENPP4	151	Q9Y6X5
SNVFSMFDQSQIQEF	MYL10	41	Q9BUA6
MLFRFSAASSDNTEN	PIK3R1	271	P27986
TFLNMFVDSNQDARR	MED14	961	O60244
FQNFSMTTDQRFNDI	MSR1	141	P21757
LMEDVENSFFLNVNS	PPT1	76	P50897
MATFSRQEFFQQLLQ	PORCN	1	Q9H237
FQMLADPRSFDSNAF	COMMD3	11	Q9UBI1
SSTLFTSDNQMFVQF	CUBN	2181	O60494
KFNFDEMQTRRSTFD	CACNA1C	676	Q13936
EFNNSIRQLFLAFNM	DOCK5	786	Q9H7D0
DTQENRRMFSSLFQF	CCDC3	146	Q9BQI4
FFQMESQKFLAENSA	CUL3	216	Q13618
ATEAFFAMTRLFQSN	COPG2	66	Q9UBF2
FTNREQMQNFDKASF	DENND5A	546	Q6IQ26
DMDFNQLEAFLTAQT	COMMD1	66	Q8N668
NLNYTDSFDNRMLRF	DCAF8L1	536	A6NGE4
MASNNMTLFFRNASE	CD226	86	Q15762
FQSARDFLDMNFQSL	PPP1R13L	6	Q8WUF5
SRLAEMESQNCSFFN	DRP2	726	Q13474
MFRQFQADFTSLSDQ	SERPINE1	321	P05121
QRATSNVFAMFDQSQ	MYL12B	16	O14950
SDSQELQTFLFMLFF	OR4F4	11	Q96R69
MNFEISFKFRTDQLN	USH2A	1736	O75445
NSMDRRTSFEKFAQN	RGS7	456	P49802
FFSLMQAELNRFQDT	SPEF2	1151	Q9C093
LQLDFEMENFTSQSV	TMEM132E	391	Q6IEE7
FTNFSDSAMQFLEKQ	TMEM161B	201	Q8NDZ6
AANSFERAMFINYEQ	LCMT1	216	Q9UIC8
SRFEMFSNSDEAVIN	FBXL20	11	Q96IG2
NDFMFEQQRRTFATY	CDC40	121	O60508
SDVNNFFQLTVEMFD	HIP1	176	O00291
RNSDQAFRTEFNLMY	SETD5	971	Q9C0A6
FLAVANSMAFQNDIF	SCD5	111	Q86SK9
CFNTFFNFEDMQEIT	NDRG4	46	Q9ULP0
MDAFTRFTNQTQGRD	PEX11A	1	O75192
MQQFQELSAEFSRAS	SMCR8	166	Q8TEV9
VNSLFNRSFNVFRQM	CLUL1	191	Q15846
SSFSFFQRSSVQEFM	YKT6	26	O15498
NSFARQQMFEFDTKT	UCHL5	141	Q9Y5K5
QDTFMENYFTSQRDN	RRAGA	66	Q7L523
AASFQSMEVRNSNFA	RRAGA	246	Q7L523
FQNSFSQAIEAAFMK	RNF10	761	Q8N5U6
FFMSLLNFLNNFQTA	VPS13C	1711	Q709C8
LAASFQSMEVRNSNF	RRAGB	306	Q5VZM2
QSMEVRNSNFAAFID	RRAGB	311	Q5VZM2
FEMCQEFEQNASTFL	SPTA1	2156	P02549
ADARSFEMTEFNQAL	RIOK2	386	Q9BVS4
EFSRMVLNSFQDSNN	ZSCAN4	41	Q8NAM6
LTRFQDSMVNSFQFS	ZNF225	111	Q9UK10
ISFARSPFNMAAFDQ	TOPORS	356	Q9NS56
VSMSALECQFQFRFE	WNT9A	86	O14904
SDIFSIFNDLNASMQ	ZBED9	1106	Q6R2W3
NTENMNLEAFDSVFI	TASOR2	1246	Q5VWN6
NAFSIIETENSNNMF	ZBTB38	166	Q8NAP3
NKQRMSNLAQFDSDF	YIPF7	21	Q8N8F6
NRFQDAVLANSFFIM	UBR4	271	Q5T4S7
FTVDVFHFANDSRNM	POMZP3	101	Q6PJE2
AAMSFEAFQRQIFDE	TBRG1	341	Q3YBR2