Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbeta-catenin binding

CDH2 CDH4 NOS2 CDH6 CDH7 CDH9

9.33e-06120816GO:0008013
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN3 NLGN4X NLGN4Y

3.47e-0516813GO:0042043
GeneOntologyMolecularFunctioncell adhesion molecule binding

NLGN3 NLGN4X NLGN4Y CDH2 CDH4 NOS2 TENM2 CDH6 CDH7 CDH9

1.52e-045998110GO:0050839
GeneOntologyBiologicalProcesspresynaptic membrane assembly

IL1RAPL1 NLGN3 NLGN4X NLGN4Y

3.71e-0810774GO:0097105
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NLGN3 NLGN4X NLGN4Y CDH2

5.81e-0811774GO:0097104
GeneOntologyBiologicalProcesspresynaptic membrane organization

IL1RAPL1 NLGN3 NLGN4X NLGN4Y

1.25e-0713774GO:0097090
GeneOntologyBiologicalProcessmembrane assembly

IL1RAPL1 NLGN3 SIRT2 NLGN4X NLGN4Y CDH2

1.40e-0764776GO:0071709
GeneOntologyBiologicalProcessmembrane biogenesis

IL1RAPL1 NLGN3 SIRT2 NLGN4X NLGN4Y CDH2

3.10e-0773776GO:0044091
GeneOntologyBiologicalProcesscell-cell adhesion mediated by cadherin

CDH2 CDH4 CDH6 CDH7 CDH9

1.18e-0650775GO:0044331
GeneOntologyBiologicalProcesscell junction assembly

IL1RAPL1 CACNA1A NLGN3 SRPX2 NLGN4X NLGN4Y EPB41L5 CDH2 CDH4 CDH6 CDH7 CDH9

1.24e-065697712GO:0034329
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

CDH2 CDH4 CDH6 CDH7 CDH9

1.59e-0653775GO:0016339
GeneOntologyBiologicalProcessvocalization behavior

NLGN3 SRPX2 NLGN4X NLGN4Y

1.80e-0624774GO:0071625
GeneOntologyBiologicalProcessadherens junction organization

CDH2 CDH4 CDH6 CDH7 CDH9

3.21e-0661775GO:0034332
GeneOntologyBiologicalProcesssynapse assembly

IL1RAPL1 CACNA1A NLGN3 SRPX2 NLGN4X NLGN4Y CDH2 CDH9

1.94e-05308778GO:0007416
GeneOntologyBiologicalProcessnegative regulation of excitatory postsynaptic potential

NLGN3 NLGN4X SYNE1

2.20e-0515773GO:0090394
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NLGN3 NLGN4X NLGN4Y

2.71e-0516773GO:0007158
GeneOntologyBiologicalProcesscell-cell adhesion

IL1RAPL1 NLGN3 ARID1B SRPX2 NLGN4X NLGN4Y EPB41L5 ARID1A CDH2 CDH4 TENM2 CDH6 CDH7 CDH9

3.96e-0510777714GO:0098609
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4X NLGN4Y

4.12e-053772GO:0002124
GeneOntologyBiologicalProcesspostsynaptic membrane organization

NLGN3 NLGN4X NLGN4Y CDH2

5.69e-0556774GO:0001941
GeneOntologyBiologicalProcesscell junction organization

IL1RAPL1 CACNA1A NLGN3 SRPX2 NLGN4X NLGN4Y EPB41L5 FGFR2 CDH2 CDH4 CDH6 CDH7 CDH9

5.93e-059747713GO:0034330
GeneOntologyBiologicalProcesspresynapse assembly

IL1RAPL1 NLGN3 NLGN4X NLGN4Y

7.47e-0560774GO:0099054
GeneOntologyBiologicalProcessmale courtship behavior

NLGN4X NLGN4Y

8.21e-054772GO:0008049
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

IL1RAPL1 CDH2 CDH4 TENM2

9.05e-0563774GO:0007157
GeneOntologyBiologicalProcesspresynapse organization

IL1RAPL1 NLGN3 NLGN4X NLGN4Y

1.61e-0473774GO:0099172
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

IL1RAPL1 CDH2 CDH4 TENM2 CDH6 CDH7 CDH9

1.68e-04313777GO:0098742
GeneOntologyBiologicalProcessvesicle-mediated transport in synapse

CACNA1A NLGN3 SIRT2 NLGN4X NLGN4Y SYNE1 CDH2

1.96e-04321777GO:0099003
GeneOntologyBiologicalProcessrhythmic synaptic transmission

CACNA1A NLGN3

2.04e-046772GO:0060024
GeneOntologyBiologicalProcesssynapse organization

IL1RAPL1 CACNA1A NLGN3 SRPX2 NLGN4X NLGN4Y FGFR2 CDH2 CDH6 CDH9

2.25e-046857710GO:0050808
GeneOntologyBiologicalProcesscourtship behavior

NLGN4X NLGN4Y

2.85e-047772GO:0007619
GeneOntologyBiologicalProcesscell-cell junction organization

NLGN4X CDH2 CDH4 CDH6 CDH7 CDH9

3.17e-04246776GO:0045216
GeneOntologyBiologicalProcesscircadian rhythm

USP2 NLGN3 NFILZ NFIL3 PIWIL2 NOS2

3.31e-04248776GO:0007623
GeneOntologyBiologicalProcessbrainstem development

NLGN4X NLGN4Y

3.80e-048772GO:0003360
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle clustering

NLGN3 CDH2

3.80e-048772GO:2000809
GeneOntologyBiologicalProcesscell-cell junction assembly

CDH2 CDH4 CDH6 CDH7 CDH9

4.05e-04167775GO:0007043
GeneOntologyBiologicalProcesspostsynapse assembly

NLGN3 NLGN4X NLGN4Y CDH2

4.08e-0493774GO:0099068
GeneOntologyBiologicalProcesssynaptic membrane adhesion

IL1RAPL1 CDH6 CDH9

5.17e-0442773GO:0099560
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CDH2 CDH4 CDH6 CDH7 CDH9

6.77e-04187775GO:0007156
GeneOntologyBiologicalProcesstrans-synaptic signaling

IL1RAPL1 CACNA1A NLGN3 ARID1B NLGN4X NLGN4Y SYNE1 GRIA4 CDH2 TENM2 FABP5

7.00e-049397711GO:0099537
GeneOntologyBiologicalProcesstrans-synaptic signaling by trans-synaptic complex

IL1RAPL1 TENM2

7.40e-0411772GO:0099545
GeneOntologyBiologicalProcessregulation of oligodendrocyte progenitor proliferation

SIRT2 CDH2

8.86e-0412772GO:0070445
GeneOntologyBiologicalProcessregulation of synaptic vesicle clustering

NLGN3 CDH2

8.86e-0412772GO:2000807
GeneOntologyBiologicalProcessneuron-neuron synaptic transmission

CACNA1A ARID1B

8.86e-0412772GO:0007270
GeneOntologyCellularComponentcatenin complex

CDH2 CDH4 CDH6 CDH7 CDH9

1.52e-0732825GO:0016342
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN3 NLGN4X NLGN4Y

2.32e-074823GO:0098983
GeneOntologyCellularComponentpostsynaptic membrane

IL1RAPL1 CACNA1A NLGN3 NLGN4X NLGN4Y SYNE1 GRIA4 CDH2 TENM2 CDH9

4.12e-064058210GO:0045211
GeneOntologyCellularComponentsymmetric synapse

NLGN3 NLGN4X NLGN4Y

1.62e-0513823GO:0032280
GeneOntologyCellularComponentextrinsic component of plasma membrane

CDH2 CDH4 TENM2 CDH6 CDH7 CDH9

1.65e-05137826GO:0019897
GeneOntologyCellularComponentsynaptic membrane

IL1RAPL1 CACNA1A NLGN3 SRPX2 NLGN4X NLGN4Y SYNE1 GRIA4 CDH2 TENM2 CDH9

1.68e-055838211GO:0097060
GeneOntologyCellularComponentextrinsic component of membrane

PIK3R4 CDH2 CDH4 TENM2 CDH6 CDH7 CDH9

3.36e-05230827GO:0019898
GeneOntologyCellularComponentexcitatory synapse

NLGN3 SRPX2 NLGN4X NLGN4Y FGFR2

6.38e-05107825GO:0060076
GeneOntologyCellularComponentglutamatergic synapse

IL1RAPL1 CACNA1A NLGN3 SIRT2 NLGN4X NLGN4Y GRIA4 CDH2 TENM2 CDH6 CDH9 FABP5

7.85e-058178212GO:0098978
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

NLGN3 NLGN4X NLGN4Y

1.11e-0424823GO:0098985
GeneOntologyCellularComponentpostsynaptic specialization membrane

IL1RAPL1 NLGN3 NLGN4X NLGN4Y GRIA4 CDH2

1.40e-04201826GO:0099634
GeneOntologyCellularComponentadherens junction

EPB41L5 CDH2 CDH4 CDH6 CDH7 CDH9

1.87e-04212826GO:0005912
GeneOntologyCellularComponentinhibitory synapse

NLGN3 NLGN4X NLGN4Y

2.42e-0431823GO:0060077
GeneOntologyCellularComponentcell-cell junction

AKAP6 SIRT2 EPB41L5 CDH2 CDH4 TENM2 CDH6 CDH7 CDH9

5.08e-04591829GO:0005911
GeneOntologyCellularComponentbBAF complex

ARID1B ARID1A

6.70e-0410822GO:0140092
GeneOntologyCellularComponentneuron to neuron synapse

IL1RAPL1 NLGN3 NLGN4X NLGN4Y GRIA4 CDH2 CDH9 FABP5

1.02e-03523828GO:0098984
GeneOntologyCellularComponentnpBAF complex

ARID1B ARID1A

1.34e-0314822GO:0071564
GeneOntologyCellularComponentbrahma complex

ARID1B ARID1A

1.34e-0314822GO:0035060
GeneOntologyCellularComponentnBAF complex

ARID1B ARID1A

1.76e-0316822GO:0071565
GeneOntologyCellularComponentdendrite

IL1RAPL1 CACNA1A NLGN3 NLGN4X NLGN4Y SYNE1 GRIA4 MMP3 TENM2 CDH9

1.90e-038588210GO:0030425
GeneOntologyCellularComponentdendritic tree

IL1RAPL1 CACNA1A NLGN3 NLGN4X NLGN4Y SYNE1 GRIA4 MMP3 TENM2 CDH9

1.93e-038608210GO:0097447
GeneOntologyCellularComponentmembrane protein complex

AKAP6 PIK3R4 CACNA1A NDUFB11 SYNE1 BEST3 GRIA4 CACNA1I CDH2 CDH4 CDH6 CDH7 CDH9 SNTB1

1.95e-0314988214GO:0098796
GeneOntologyCellularComponentpostsynapse

IL1RAPL1 CACNA1A NLGN3 NLGN4X NLGN4Y SYNE1 GRIA4 CDH2 TENM2 CDH9 FABP5

2.04e-0310188211GO:0098794
GeneOntologyCellularComponentasymmetric synapse

IL1RAPL1 NLGN3 NLGN4X NLGN4Y GRIA4 CDH2 FABP5

2.69e-03477827GO:0032279
GeneOntologyCellularComponentglycinergic synapse

NLGN4X NLGN4Y

2.76e-0320822GO:0098690
GeneOntologyCellularComponentsomatodendritic compartment

IL1RAPL1 CACNA1A NLGN3 SIRT2 NLGN4X NLGN4Y SYNE1 GRIA4 FEV MMP3 TENM2 CDH9

2.93e-0312288212GO:0036477
GeneOntologyCellularComponentcalcium channel complex

AKAP6 CACNA1A CACNA1I

2.97e-0373823GO:0034704
GeneOntologyCellularComponentpreribosome, large subunit precursor

RPF1 BOP1

3.04e-0321822GO:0030687
GeneOntologyCellularComponentpostsynaptic density membrane

IL1RAPL1 NLGN4X NLGN4Y GRIA4

3.40e-03157824GO:0098839
GeneOntologyCellularComponentpresynaptic active zone membrane

CACNA1A GRIA4 CDH2

3.58e-0378823GO:0048787
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A GRIA4 CACNA1I CDH2 CDH4 CDH6 CDH7 CDH9 SNTB1

3.59e-03785829GO:0098797
GeneOntologyCellularComponentpostsynaptic specialization

IL1RAPL1 NLGN3 NLGN4X NLGN4Y GRIA4 CDH2 FABP5

3.60e-03503827GO:0099572
GeneOntologyCellularComponentanchoring junction

AKAP6 SIRT2 EPB41L5 CDH2 CDH4 TENM2 CDH6 CDH7 CDH9 SNTB1

4.78e-039768210GO:0070161
GeneOntologyCellularComponentsodium channel complex

GRIA4 CACNA1I

5.76e-0329822GO:0034706
GeneOntologyCellularComponentSWI/SNF complex

ARID1B ARID1A

6.16e-0330822GO:0016514
HumanPhenoLack of peer relationships

NLGN3 NLGN4X CHD2

1.23e-0510253HP:0002332
HumanPhenoAbnormal peer relationships

NLGN3 NLGN4X CHD2

1.23e-0510253HP:5200016
HumanPhenoAbnormal relationship

NLGN3 NLGN4X CHD2

5.61e-0516253HP:5200024
HumanPhenoPersonality disorder

CACNA1A CYP27A1 CHD2

8.12e-0518253HP:0012075
HumanPhenoAbnormal social development

IL1RAPL1 CACNA1A NDUFB11 NLGN3 ARID1B DNAJC13 SRPX2 NLGN4X CYP27A1 SPRED1 CHD2 ARID1A CDH2

1.05e-049082513HP:0025732
HumanPhenoLack of spontaneous play

NLGN3 NLGN4X

1.38e-044252HP:0000721
HumanPhenoAbnormal play

NLGN3 NLGN4X

1.38e-044252HP:5200104
HumanPhenoDisinhibition

IL1RAPL1 CACNA1A NLGN3 ARID1B DNAJC13 SRPX2 NLGN4X CYP27A1 SPRED1 CHD2 ARID1A CDH2

1.62e-048072512HP:0000734
HumanPhenoInappropriate behavior

IL1RAPL1 CACNA1A NLGN3 ARID1B DNAJC13 SRPX2 NLGN4X CYP27A1 SPRED1 CHD2 ARID1A CDH2

1.62e-048072512HP:0000719
HumanPhenoAbnormal response to social norms

IL1RAPL1 CACNA1A NLGN3 ARID1B DNAJC13 SRPX2 NLGN4X CYP27A1 SPRED1 CHD2 ARID1A CDH2

1.62e-048072512HP:5200123
HumanPhenoSocial disinhibition

IL1RAPL1 CACNA1A NLGN3 ARID1B DNAJC13 SRPX2 NLGN4X CYP27A1 SPRED1 CHD2 ARID1A CDH2

1.62e-048072512HP:5200029
DomainCadherin_cytoplasmic-dom

CDH2 CDH4 CDH6 CDH7 CDH9

6.31e-0825805IPR000233
DomainCadherin_C

CDH2 CDH4 CDH6 CDH7 CDH9

6.31e-0825805PF01049
DomainCatenin_binding_dom

CDH2 CDH4 CDH6 CDH7 CDH9

1.39e-0729805IPR027397
Domain-

CDH2 CDH4 CDH6 CDH7 CDH9

1.39e-07298054.10.900.10
DomainNlgn

NLGN3 NLGN4X NLGN4Y

7.52e-075803IPR000460
DomainBAF250_C

ARID1B ARID1A

1.81e-052802IPR033388
DomainNLGN4

NLGN4X NLGN4Y

1.81e-052802IPR030025
DomainBAF250_C

ARID1B ARID1A

1.81e-052802PF12031
DomainBAF250/Osa

ARID1B ARID1A

1.81e-052802IPR021906
DomainCarboxylesterase_B_CS

NLGN3 NLGN4X NLGN4Y

2.10e-0513803IPR019819
DomainCARBOXYLESTERASE_B_2

NLGN3 NLGN4X NLGN4Y

2.66e-0514803PS00941
DomainCOesterase

NLGN3 NLGN4X NLGN4Y

2.66e-0514803PF00135
DomainCarbesteraseB

NLGN3 NLGN4X NLGN4Y

2.66e-0514803IPR002018
Domain-

PIK3R4 ARID1B DNAJC13 HEATR4 ANKAR ARID1A KPNB1

4.64e-052228071.25.10.10
DomainCadherin_CS

CDH2 CDH4 CDH6 CDH7 CDH9

1.05e-04109805IPR020894
DomainCADHERIN_1

CDH2 CDH4 CDH6 CDH7 CDH9

1.24e-04113805PS00232
DomainCadherin

CDH2 CDH4 CDH6 CDH7 CDH9

1.24e-04113805PF00028
DomainCADHERIN_2

CDH2 CDH4 CDH6 CDH7 CDH9

1.30e-04114805PS50268
Domain-

CDH2 CDH4 CDH6 CDH7 CDH9

1.30e-041148052.60.40.60
DomainCA

CDH2 CDH4 CDH6 CDH7 CDH9

1.35e-04115805SM00112
DomainCadherin-like

CDH2 CDH4 CDH6 CDH7 CDH9

1.41e-04116805IPR015919
DomainCadherin

CDH2 CDH4 CDH6 CDH7 CDH9

1.52e-04118805IPR002126
DomainARM-like

PIK3R4 ARID1B DNAJC13 HEATR4 ANKAR ARID1A KPNB1

1.58e-04270807IPR011989
DomainCadherin_pro

CDH2 CDH4

3.75e-047802PF08758
DomainCadherin_pro_dom

CDH2 CDH4

4.99e-048802IPR014868
DomainCadherin_pro

CDH2 CDH4

4.99e-048802SM01055
DomainVDCCAlpha1

CACNA1A CACNA1I

7.97e-0410802IPR002077
DomainHEAT

PIK3R4 HEATR4 KPNB1

1.14e-0348803PF02985
DomainOLF

OLFML2A OLFML2B

1.37e-0313802PS51132
DomainOlfac-like_dom

OLFML2A OLFML2B

1.37e-0313802IPR003112
DomainOLF

OLFML2A OLFML2B

1.37e-0313802SM00284
DomainOLF

OLFML2A OLFML2B

1.37e-0313802PF02191
Domain-

ARID1B ARID1A

1.83e-03158021.10.150.60
DomainPept_M10A_Zn_BS

MMP3 MMP15

1.83e-0315802IPR021158
DomainBRIGHT

ARID1B ARID1A

1.83e-0315802SM00501
DomainARID_dom

ARID1B ARID1A

1.83e-0315802IPR001606
DomainARID

ARID1B ARID1A

1.83e-0315802PS51011
DomainARID

ARID1B ARID1A

1.83e-0315802PF01388
DomainHEAT

PIK3R4 HEATR4 KPNB1

1.97e-0358803IPR000357
DomainHEAT_type_2

PIK3R4 KPNB1

2.36e-0317802IPR021133
DomainHemopexin_CS

MMP3 MMP15

2.36e-0317802IPR018486
DomainPept_M10A_stromelysin-type

MMP3 MMP15

2.65e-0318802IPR016293
DomainPG_binding_1

MMP3 MMP15

3.27e-0320802PF01471
DomainPeptidoglycan-bd-like

MMP3 MMP15

3.27e-0320802IPR002477
DomainARM-type_fold

PIK3R4 DNAJC13 HEATR4 ANKAR ARID1A KPNB1

3.33e-03339806IPR016024
DomainHEAT_REPEAT

PIK3R4 HEATR4 KPNB1

3.37e-0370803PS50077
DomainHemopexin-like_dom

MMP3 MMP15

4.32e-0323802IPR000585
DomainHemopexin-like_repeat

MMP3 MMP15

4.32e-0323802IPR018487
DomainM10A_MMP

MMP3 MMP15

4.32e-0323802IPR033739
DomainHemopexin

MMP3 MMP15

4.32e-0323802PF00045
DomainHEMOPEXIN

MMP3 MMP15

4.32e-0323802PS00024
Domain-

MMP3 MMP15

4.32e-03238022.110.10.10
DomainHEMOPEXIN_2

MMP3 MMP15

4.32e-0323802PS51642
DomainHX

MMP3 MMP15

4.32e-0323802SM00120
DomainPept_M10A

MMP3 MMP15

4.32e-0323802IPR021190
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

IL1RAPL1 NLGN3 NLGN4X NLGN4Y EPB41L5 GRIA4

6.08e-0767656MM15327
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

CDH2 CDH4 CDH6 CDH7 CDH9

1.04e-0640655MM15060
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

CDH2 CDH4 CDH6 CDH7 CDH9

2.62e-0648655MM15069
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

IL1RAPL1 NLGN3 NLGN4X NLGN4Y EPB41L5 GRIA4

2.86e-0687656M27617
PathwayWP_HIPPO_SIGNALING_REGULATION

FGFR2 CDH2 CDH4 CDH6 CDH7 CDH9

5.74e-0698656M39830
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

CDH2 CDH4 CDH6 CDH7 CDH9

6.76e-0658655M11980
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN3 NLGN4X NLGN4Y EPB41L5

1.34e-0532654MM15326
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

FGFR2 CDH2 CDH4 CDH6 CDH7 CDH9

1.93e-05121656M39823
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

CDH2 CDH4 CDH6 CDH7 CDH9

2.10e-0573655MM15126
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

CDH2 CDH4 CDH6 CDH7 CDH9

5.79e-0590655M820
PathwayWP_NRXN1_DELETION_SYNDROME

NLGN3 NLGN4X GRIA4

7.27e-0518653M48098
PathwayREACTOME_CELL_CELL_COMMUNICATION

CDH2 CDH4 CDH6 CDH7 CDH9

7.89e-0596655MM14592
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN3 NLGN4X NLGN4Y EPB41L5

1.26e-0456654M27616
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

CDH2 CDH4 CDH6 CDH7 CDH9

2.01e-04117655M19248
PathwayREACTOME_CELL_CELL_COMMUNICATION

CDH2 CDH4 CDH6 CDH7 CDH9

7.32e-04155655M522
PathwayREACTOME_NEURONAL_SYSTEM

IL1RAPL1 CACNA1A NLGN3 NLGN4X NLGN4Y EPB41L5 GRIA4

8.58e-04335657MM14503
Pubmed

Differential Spatiotemporal Expression of Type I and Type II Cadherins Associated With the Segmentation of the Central Nervous System and Formation of Brain Nuclei in the Developing Mouse.

CDH2 CDH4 CDH6 CDH7 CDH9

1.90e-101582533833667
Pubmed

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.

CDH2 CDH4 CDH6 CDH7 CDH9

9.71e-10208257806582
Pubmed

Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

CDH2 CDH4 CDH6 CDH9

5.96e-09108242059658
Pubmed

Motor neuron position and topographic order imposed by β- and γ-catenin activities.

CDH2 CDH4 CDH6 CDH7 CDH9

7.31e-092982522036570
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN3 NLGN4X NLGN4Y

1.26e-08382332011705
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN3 NLGN4X NLGN4Y

1.26e-08382318628683
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN3 NLGN4X NLGN4Y

5.04e-08482312669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN3 NLGN4X NLGN4Y

5.04e-08482322671294
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN3 NLGN4X NLGN4Y

5.04e-08482320579107
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN3 NLGN4X NLGN4Y

5.04e-08482316077734
Pubmed

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.

NLGN3 NLGN4X NLGN4Y

5.04e-08482317292328
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

CDH2 CDH4 TENM2 CDH6 CDH7 CDH9

8.10e-089182628558017
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN3 NLGN4X NLGN4Y

1.26e-07582310996085
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN3 NLGN4X NLGN4Y

1.26e-07582337865312
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN3 NLGN4X NLGN4Y

2.51e-07682321838267
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN3 NLGN4X NLGN4Y

2.51e-07682329724786
Pubmed

Type II cadherins guide assembly of a direction-selective retinal circuit.

CDH4 CDH6 CDH7 CDH9

2.94e-072482425126785
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

IL1RAPL1 ARID1B WDR64 CEP295 CHD2 COLGALT2 ARID1A HSPA12B BABAM2 ZNF687 DNAH11

3.13e-07638821131182584
Pubmed

DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.

NLGN3 NLGN4X NLGN4Y CDH2

4.12e-072682434848499
Pubmed

A comprehensive survey of the cadherins expressed in the testes of fetal, immature, and adult mice utilizing the polymerase chain reaction.

CDH2 CDH6 CDH9

4.39e-0778238879495
Pubmed

Genetic dissection of cadherin function during nephrogenesis.

CDH2 CDH4 CDH6

4.39e-07782311839813
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NLGN3 NLGN4X NLGN4Y

7.01e-07882330871858
Pubmed

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.

NLGN3 NLGN4X NLGN4Y

1.05e-06982323010509
Pubmed

Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

CDH6 CDH7 CDH9

1.50e-061082310861224
Pubmed

Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex.

CDH2 CDH4 CDH6

1.50e-061082327151949
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

ARID1B PHF19 CHD2 ARID1A CDH4 CDH7

2.03e-0615782630186101
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NLGN3 NLGN4X NLGN4Y

2.06e-061182332973045
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

NLGN3 NLGN4X NLGN4Y

2.06e-061182326403076
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 ARID1B UACA CLK1 NFIL3 SYNE1 SPRED1 CHD2 KPNB1

2.69e-0649782923414517
Pubmed

Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.

CDH6 CDH7 CDH9

2.74e-061282322102170
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NLGN3 NLGN4X NLGN4Y

3.55e-061382327050589
Pubmed

Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.

CDH2 CDH6 CDH7

3.55e-06138239615235
Pubmed

Congenital Diaphragmatic Hernia Overview

NDUFB11 ARID1B FGFR2 ARID1A

4.34e-064682420301533
Pubmed

Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse.

CDH4 CDH6 CDH7

4.51e-061482320847152
Pubmed

Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.

CDH2 CDH4

5.49e-0628228247017
Pubmed

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.

ARID1B ARID1A

5.49e-06282234386776
Pubmed

Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort.

NLGN3 NLGN4X

5.49e-06282227782075
Pubmed

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

ARID1B ARID1A

5.49e-06282223202128
Pubmed

Not all neuroligin 3 and 4X missense variants lead to significant functional inactivation.

NLGN3 NLGN4X

5.49e-06282228948087
Pubmed

ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.

ARID1B ARID1A

5.49e-06282233890484
Pubmed

Role of cadherins in maintaining the compartment boundary between the cortex and striatum during development.

CDH4 CDH6

5.49e-06282211171339
Pubmed

Novel splice isoforms for NLGN3 and NLGN4 with possible implications in autism.

NLGN3 NLGN4X

5.49e-06282216648374
Pubmed

A substitution involving the NLGN4 gene associated with autistic behavior in the Greek population.

NLGN3 NLGN4X

5.49e-06282219645625
Pubmed

Unusually rapid evolution of Neuroligin-4 in mice.

NLGN4X NLGN4Y

5.49e-06282218434543
Pubmed

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

ARID1B ARID1A

5.49e-06282224562383
Pubmed

Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands.

NLGN3 NLGN4X

5.49e-06282215274046
Pubmed

Identification and characterization of photomedins: novel olfactomedin-domain-containing proteins with chondroitin sulphate-E-binding activity.

OLFML2A OLFML2B

5.49e-06282215836428
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4X NLGN4Y

5.49e-06282223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4X NLGN4Y

5.49e-06282224855039
Pubmed

Analysis of the genes encoding neuroligins NLGN3 and NLGN4 in Bulgarian patients with autism.

NLGN3 NLGN4X

5.49e-06282223431752
Pubmed

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.

NLGN4X NLGN4Y

5.49e-06282237001827
Pubmed

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.

NLGN4X NLGN4Y

5.49e-06282237080762
Pubmed

Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection.

NLGN3 NLGN4X

5.49e-06282216508939
Pubmed

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.

ARID1B ARID1A

5.49e-06282237611161
Pubmed

Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.

ARID1B ARID1A

5.49e-06282232791957
Pubmed

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.

ARID1B ARID1A

5.49e-06282229890703
Pubmed

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

NLGN4X NLGN4Y

5.49e-06282229106499
Pubmed

NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population.

NLGN3 NLGN4X

5.49e-06282215389766
Pubmed

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

NLGN4X NLGN4Y

5.49e-06282226456829
Pubmed

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.

NLGN4X NLGN4Y

5.49e-06282224104404
Pubmed

Association of SLC12A1 and GLUR4 Ion Transporters with Neoadjuvant Chemoresistance in Luminal Locally Advanced Breast Cancer.

SLC12A1 GRIA4

5.49e-06282238003293
Pubmed

Functional cis-heterodimers of N- and R-cadherins.

CDH2 CDH4

5.49e-06282210662782
Pubmed

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

ARID1B ARID1A

5.49e-06282224788099
Pubmed

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

NLGN4X NLGN4Y

5.49e-06282232243781
Pubmed

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

ARID1B ARID1A

5.49e-06282228967863
Pubmed

Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.

ARID1B ARID1A

5.49e-06282233052929
Pubmed

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

NLGN4X NLGN4Y

5.49e-06282222989184
Pubmed

Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.

NLGN3 NLGN4X

5.49e-06282224570023
Pubmed

No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level.

NLGN3 NLGN4X

5.49e-06282218189281
Pubmed

Genome-wide association study reveals two loci for serum magnesium concentrations in European-American children.

FGFR2 PAPSS2

5.49e-06282226685716
Pubmed

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

ARID1B ARID1A

5.49e-06282227562491
Pubmed

Disorder-associated mutations lead to functional inactivation of neuroligins.

NLGN3 NLGN4X

5.49e-06282215150161
Pubmed

Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients.

NLGN3 NLGN4X

5.49e-06282215622415
Pubmed

PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2.

SIRT2 PHF19

5.49e-06282233611744
Pubmed

Mutation screening in the Greek population and evaluation of NLGN3 and NLGN4X genes causal factors for autism.

NLGN3 NLGN4X

5.49e-06282223851596
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

NLGN3 NLGN4X NLGN4Y

5.63e-061582318227507
Pubmed

Cadherin expression in the developing mouse olfactory system.

CDH2 CDH4 CDH6

6.92e-061682317278136
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A NLGN3 DNAJC13 UACA MAGED2 SYNE1 YLPM1 GRIA4 CDH2 TENM2 KPNB1

1.62e-05963821128671696
Pubmed

Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.

ARID1B ARID1A

1.64e-05382233432679
Pubmed

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.

ARID1B ARID1A

1.64e-05382221647563
Pubmed

Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation.

CDH6 CDH9

1.64e-05382229760652
Pubmed

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

ARID1B ARID1A

1.64e-05382234044070
Pubmed

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.

ARID1B ARID1A

1.64e-05382226716708
Pubmed

Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung's disease.

NLGN3 NLGN4X

1.64e-05382229622757
Pubmed

Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability.

CHD2 CDH2

1.64e-05382231704914
Pubmed

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.

NFIL3 BOP1

1.64e-05382226156959
Pubmed

Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

ARID1B ARID1A

1.64e-05382222426308
Pubmed

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.

ARID1B ARID1A

1.64e-05382224382590
Pubmed

Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas.

CDH2 CDH4

1.64e-0538221406710
Pubmed

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

NLGN4X NLGN4Y

1.64e-05382221282647
Pubmed

ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.

ARID1B ARID1A

1.64e-05382234512623
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

CACNA1A ZNF862 SYNE1 CEP295 HSPA12B DNAH11

1.94e-0523382637704626
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PIK3R4 CACNA1A NDUFB11 NLGN3 SIRT2 DNAJC13 SYNE1 ARID1A NT5DC3 CDH2 MRPS22 KPNB1 DNAH11

2.91e-051431821337142655
Pubmed

Functional roles of MMP14 and MMP15 in early postnatal mammary gland development.

MMP3 MMP15

3.28e-05482227633994
Pubmed

Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy.

MMP3 NOS2

3.28e-05482214673996
Pubmed

Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.

NLGN3 KPNB1

3.28e-05482238254206
Pubmed

Heterophilic Type II Cadherins Are Required for High-Magnitude Synaptic Potentiation in the Hippocampus.

CDH6 CDH9

3.28e-05482228957665
Pubmed

Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity.

CDH2 CDH4

3.28e-05482216461340
Pubmed

Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.

NLGN3 NLGN4X

3.28e-05482223468870
Pubmed

N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption.

FGFR2 CDH2

3.28e-05482216705170
InteractionCDH7 interactions

CDH6 CDH7 CDH9

3.45e-068813int:CDH7
InteractionCDH6 interactions

CDH6 CDH7 CDH9

3.45e-068813int:CDH6
InteractionCDH9 interactions

CDH6 CDH7 CDH9

1.34e-0512813int:CDH9
GeneFamilyCD molecules|Type II classical cadherins

CDH6 CDH7 CDH9

9.22e-06135931186
GeneFamilyCD molecules|Type I classical cadherins

CDH2 CDH4

1.04e-0455921185
GeneFamilyAT-rich interaction domain containing

ARID1B ARID1A

1.07e-0315592418
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP3 MMP15

2.76e-0324592891
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1I

3.24e-0326592253
ToppCell18-Distal-Epithelial-Basal_cell|Distal / Age, Tissue, Lineage and Cell class

CACNA1A DNAJC13 CHSY3 CEP295 COLGALT2 CDH2

4.79e-07158826183f445967e09e871c93d8e94781ed9fec894169
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA OLFML2B CDH6 INPP4B FABP5 DNAH11

6.18e-07165826369d77a80d6401e85ea3121ab5a252f67d5f157e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 OLFML2A NLGN4X CDH2 CDH6 SNTB1

6.86e-07168826af82e07d1eec51fc6530155f37addbce6221885d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLGN4Y OLFML2B GRIA4 CDH2 CDH6 SNTB1

7.35e-071708265570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL1RAPL1 OLFML2B CDH2 TENM2 CDH6 INPP4B

7.61e-071718264ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NLGN3 MMP15 CDH2 CDH4 CDH6 SNTB1

9.31e-071778260417460bdb012bc43d7254377fa53d79cdab3f34
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 OLFML2A NLGN4X MMP15 CDH2 CDH6

1.06e-06181826098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP2 SLC12A1 COLGALT2 FGFR2 TENM2 DNAH11

1.20e-06185826af86e75096c1812ae27a78405355957ee8043d84
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 OLFML2B SYNE1 TENM2 CDH6 INPP4B

1.24e-061868264780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OLFML2A UACA CHSY3 PAPSS2 CDH6 INPP4B

1.63e-06195826d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 OLFML2A NLGN4X MMP15 CDH2 CDH6

1.79e-0619882652ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA OLFML2B CDH6 INPP4B FABP5 DNAH11

1.84e-061998269e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6 INPP4B

1.89e-062008269169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6 INPP4B

1.89e-06200826a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6 INPP4B

1.89e-06200826c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A GRIA4 IQCM CDH6 CDH9

5.90e-06139825a1945b07f177cde40e7eea03a19236ce76165857
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A WDR64 GRIA4 CDH4 IQCM

8.01e-06148825d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

IL1RAPL1 CACNA1A CDH4 IQCM TENM2

1.13e-051598255335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellwk_20-22-Epithelial-PNS|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

OLFML2A NLGN3 NLGN4X CDH2 CDH6

1.70e-0517382517b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL1RAPL1 NLGN3 NLGN4X MMP15 CDH6

1.80e-05175825bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL1RAPL1 NLGN3 NLGN4X MMP15 CDH6

1.80e-051758258b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL1RAPL1 NLGN3 NLGN4X MMP15 CDH6

1.80e-051758250b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 CDH2 CDH4 SNTB1 DNAH11

1.90e-05177825da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHSY3 COLGALT2 CDH6 INPP4B DNAH11

1.90e-05177825a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHSY3 COLGALT2 CDH6 INPP4B DNAH11

1.90e-051778253645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

OLFML2A NLGN4X MMP15 CDH6 SNTB1

1.90e-0517782559726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SRPX2 OLFML2B FGFR2 CDH2 CDH6

1.95e-05178825e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 OLFML2A CDH6 SNTB1 INPP4B

2.01e-051798258da6863edc756540bb097cc7221c1408640d9bb4
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 OLFML2A CDH6 SNTB1 INPP4B

2.01e-05179825f39c13c99a07d009cc677e363ffe089089c64916
ToppCellLV|World / Chamber and Cluster_Paper

AKAP6 IL1RAPL1 CDH2 TENM2 INPP4B

2.06e-051808255ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 OLFML2A USP2 CDH6 SNTB1

2.06e-051808250059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

UACA MAGED2 OLFML2B CDH2 FABP5

2.06e-0518082538035cf2c6fbc443ea10ca7e942572715ed572da
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 OLFML2A USP2 CDH6 SNTB1

2.06e-05180825dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 OLFML2A NLGN4X CDH2 CDH6

2.12e-05181825a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

OLFML2A NLGN4X MMP15 CDH6 SNTB1

2.17e-05182825b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NLGN4Y TIGD1 CHSY3 PIWIL2 NOS2

2.17e-05182825d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NLGN4Y TIGD1 CHSY3 PIWIL2 NOS2

2.17e-0518282592f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 MAGED2 OLFML2B HSPA12B SNTB1

2.17e-05182825f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NLGN4Y TIGD1 CHSY3 PIWIL2 NOS2

2.17e-0518282502baca9a72c7b559c3e452693b3b134af804c868
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A SPRED1 MMP15 CDH4 CDH6

2.23e-05183825547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 SLC12A1 NLGN4X PAPSS2 SNTB1

2.29e-05184825d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A NLGN3 NLGN4X CDH2 CDH6

2.29e-05184825226ccac00ac1c3a0ad7283785fd14312320e0ca6
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 IL1RAPL1 CDH2 TENM2 INPP4B

2.35e-05185825549eeb521c3985bff396ea0f202db21822efa51f
ToppCellwk_08-11-Epithelial-PNS-COL20A1+_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

OLFML2A WDR64 NLGN4X CDH6 SNTB1

2.35e-05185825abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 GRIA4 CHSY3 CDH7 CDH9

2.41e-051868258915436d09775f2828a7678af203b1082b36e21c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 OLFML2B TENM2 CDH6 INPP4B

2.41e-05186825a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

AKAP6 IL1RAPL1 CDH2 TENM2 INPP4B

2.54e-051888250758b474457efa36488e0195f7357100f4b6a090
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A NLGN3 NLGN4X CDH2 CDH6

2.54e-05188825ccd2541892112a7a303f766adf9a7afeb754498c
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

AKAP6 IL1RAPL1 CDH2 TENM2 INPP4B

2.60e-051898259c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 IL1RAPL1 OLFML2B TENM2 CDH6

2.60e-05189825975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

OLFML2A CDH6 INPP4B FABP5 DNAH11

2.60e-051898259c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 CHSY3 NT5DC3 CDH6 INPP4B

2.60e-051898256b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

AKAP6 IL1RAPL1 CDH2 TENM2 INPP4B

2.67e-05190825de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

WSB1 SRPX2 NLGN4X CYP27A1 SNTB1

2.67e-0519082512992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 OLFML2B TENM2 CDH6 INPP4B

2.67e-0519082573d94fbae92029745989a8712eed8b99fd84c193
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UBTD1 NLGN4X SPRED1 MMP3 PAPSS2

2.67e-0519082539fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A GRIA4 CDH6 INPP4B DNAH11

2.74e-05191825239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL1RAPL1 UACA SYNE1 HSPA12B NOS2

2.74e-05191825f229abf69a1217194f74b0502486907e07dba989
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

WSB1 SRPX2 NLGN4X NLGN4Y SNTB1

2.74e-05191825d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NLGN4X OLFML2B CDH6 INPP4B FABP5

2.81e-0519282555f95454399fd533df75db06584eaa48d6ee3830
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP6 OLFML2A MAGED2 OLFML2B CDH2

2.88e-05193825469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NLGN3 NLGN4X MMP15 CDH2 CDH6

2.88e-05193825d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA OLFML2B CDH6 INPP4B FABP5

2.88e-05193825a9349ed5f3c34dcf817b3e84737e5946922ddff3
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A MMP15 CDH2 CDH6 SNTB1

2.88e-05193825cdc44bf6f5436eb8a2d4720fe011dcb85ccecf87
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SRPX2 OLFML2B FGFR2 MMP3 CDH2

2.88e-05193825035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

OLFML2A SRPX2 NLGN4Y CDH4 TENM2

2.95e-0519482535f132cc38ac133be01834ed0946188aa0757eb4
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-immature_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UACA MAGED2 NLGN4Y HSPA12B FABP5

2.95e-05194825bf8e78d53802ac758be1c3db833779c26a94e1d5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2B CDH6 INPP4B FABP5 DNAH11

2.95e-051948253b9ada901dfe7a5cc4861a883d3268c53b11e5b6
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OLFML2B SYNE1 EPB41L5 CDH2 CDH6

3.10e-0519682534e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OLFML2A UACA OLFML2B PAPSS2 CDH6

3.10e-05196825cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2B CDH6 INPP4B FABP5 DNAH11

3.10e-05196825624f700daea48d9bad4cc554f4776bd809ae1e54
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

OLFML2A NLGN3 CDH2 CDH6 CDH7

3.10e-05196825b6226163d9fc93ecfff2115bb74408303a000490
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OLFML2B SYNE1 EPB41L5 CDH2 CDH6

3.10e-051968258f82e01ca50aa4cd6149547505b4474a02fad618
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OLFML2A UACA OLFML2B PAPSS2 CDH6

3.10e-0519682544e2df1b61e3819eae7e482bef0a733afe852d67
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

OLFML2B CYP27A1 SPRED1 PAPSS2 FABP5

3.18e-051978255fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 USP2 SYNE1 CDH6 DNAH11

3.18e-05197825ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A MMP15 CDH2 CDH6 SNTB1

3.25e-0519882536c97eb71b89bac01cabd6a8b728e5a20e52d2a3
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A NLGN4X MMP15 CDH2 CDH6

3.25e-0519882550dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A MMP15 CDH2 CDH6 SNTB1

3.25e-05198825c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 USP2 SYNE1 CDH6 DNAH11

3.25e-05198825c12e7511628db819a52959bb68580e27c00c2e41
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 USP2 SYNE1 CDH6 DNAH11

3.25e-0519882522e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A MMP15 CDH2 CDH6 SNTB1

3.33e-05199825ce699726ac4825c65bf934cb9a76202ad7340596
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

OLFML2A UACA MAGED2 HSPA12B PAPSS2

3.33e-0519982511c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A MMP15 CDH2 CDH6 SNTB1

3.33e-05199825f1d5808ccb1d5d4e2d34f864e705e2484000e88f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2B CDH6 INPP4B FABP5 DNAH11

3.33e-05199825f1723cfd6fbb8c8903a3b167872ec8523e3be250
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_Myelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A OLFML2A NLGN3 CDH6 CDH7

3.33e-051998252b567b6fd8addf059bbf2b72c55a7647aefdc595
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

OLFML2A SRPX2 UACA OLFML2B CDH6

3.41e-05200825ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6

3.41e-05200825b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellSevere_COVID-19-Myeloid-MoAM4|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

OLFML2B CYP27A1 SPRED1 PAPSS2 FABP5

3.41e-0520082530448a41ca64d6f0fedaff0b7a6670dd33cdf2c5
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OLFML2B CYP27A1 SPRED1 PAPSS2 FABP5

3.41e-052008254f481d87e30195365900acb5d50641a9e7b2f462
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OLFML2B CYP27A1 SPRED1 PAPSS2 FABP5

3.41e-052008255490393c5f54748f912676e19b58bd1320415a06
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML2A MMP15 CDH2 CDH6 SNTB1

3.41e-05200825de55100e98d3e9b8a74e37aebcd3afa2b0996527
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6

3.41e-052008258c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6

3.41e-05200825b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OLFML2B CYP27A1 SPRED1 PAPSS2 FABP5

3.41e-05200825cf720d3973e79ffd4c6e763a7284799ced22a274
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

OLFML2B CYP27A1 SPRED1 PAPSS2 FABP5

3.41e-05200825df821ac12953e44fcfedbbefb35a4976e406ccd6
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

AKAP6 OLFML2B SYNE1 TENM2 CDH6

3.41e-0520082577631c471cc5d453a749784f838cfa6408caf09b
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

USP2 NLGN4X GRIA4 CDH2

7.64e-051228242aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANKAR CDH4 CDH7 CDH9

8.66e-0512682428fbe63f7bc628b32d8e86bf9e80657e776dd1cc
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

AKAP6 UBTD1 CDH4 CDH6

1.30e-041408245623a0a68403fc00166b7d13d13e184a718d9bdd
Drug(+,-)-Synephrine [94-07-5]; Down 200; 24uM; HL60; HT_HG-U133A

WSB1 MAGED2 ZNF862 SYNE1 ARID1A NT5DC3 SNTB1

5.50e-061948076156_DN
DrugPHA-00851261E [724719-49-7]; Down 200; 1uM; PC3; HT_HG-U133A

OLFML2A TNFRSF25 ZNF862 EPB41L5 COLGALT2 MMP3 CDH6

5.88e-061968073776_DN
DrugLovastatin [75330-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A

WSB1 TNFRSF25 EPB41L5 FGFR2 ARID1A CDH6 CCDC70

5.88e-061968076633_UP
Drugenzacamene

IL1RAPL1 CACNA1A GRIA4 CACNA1I FGFR2 MMP3

6.28e-06129806ctd:C038939
DrugClindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A

TNFRSF25 UBTD1 ZNF862 FGFR2 MMP3 ARID1A CDH6

6.28e-061988075815_UP
DrugRaloxifene Hydrochloride

OLFML2A TNFRSF25 CLK1 NFIL3 CYP27A1 CACNA1I FGFR2 MMP3 CDH2 NOS2 CDH6 INPP4B KPNB1

8.50e-068578013ctd:D020849
Drugoctylmethoxycinnamate

IL1RAPL1 CACNA1A GRIA4 CACNA1I FGFR2 MMP3

9.63e-06139806ctd:C118580
Drugpalladium oxide

MMP3 NOS2

1.22e-052802CID000073974
Drugbutylparaben

IL1RAPL1 CACNA1A GRIA4 CACNA1I FGFR2 MMP3

1.93e-05157806ctd:C038091
Drug2-amino-6-chloropurine

SLC12A1 SYNE1 KYAT1

3.28e-0518803CID005360349
DrugMuramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A

CACNA1A USP2 TNFRSF25 ZNF862 SYNE1 MMP15

6.13e-051938063262_UP
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A

USP2 ZNF862 YLPM1 CACNA1I MMP3 ARID1A

6.49e-051958066059_DN
DrugNafronyl oxalate [3200-06-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A

WSB1 USP2 KLHL9 BABAM2 KYAT1 KPNB1

6.49e-051958065287_UP
DrugCP-863187 [668981-07-5]; Up 200; 10uM; PC3; HT_HG-U133A

WSB1 TNFRSF25 OLFML2B ZNF862 CYP27A1 CDH6

6.67e-051968067512_UP
Drug0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A

TNFRSF25 TBC1D9B KLHL9 NT5DC3 CDH7 KYAT1

6.67e-051968067391_DN
DrugSulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; HL60; HT_HG-U133A

AKAP6 OLFML2A FGFR2 CDH2 CDH4 CDH6

6.67e-051968062742_UP
DrugKetoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A

WSB1 UBTD1 ARID1A NT5DC3 BABAM2 CDH6

6.86e-051978064751_DN
DrugDanazol [17230-88-5]; Up 200; 11.8uM; HL60; HG-U133A

CACNA1A UBTD1 CYP27A1 CACNA1I FGFR2 CDH6

6.86e-051978062038_UP
DrugAcetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A

AKAP6 TNFRSF25 ZNF862 CYP27A1 CACNA1I BABAM2

6.86e-051978063364_UP
DrugTiaprofenic acid [33005-95-7]; Up 200; 15.4uM; HL60; HT_HG-U133A

AKAP6 IL1RAPL1 OLFML2A YLPM1 MMP3 CDH2

7.06e-051988062492_UP
DrugTheobromine [83-67-0]; Down 200; 22.2uM; HL60; HT_HG-U133A

SRPX2 YLPM1 FGFR2 NT5DC3 CDH6 SNTB1

7.06e-051988062995_DN
DrugTropine [120-29-6]; Down 200; 28.4uM; PC3; HT_HG-U133A

TNFRSF25 ZNF862 MMP3 PAPSS2 NT5DC3 BABAM2

7.06e-051988065790_DN
DrugTroleandomycin [2751-09-9]; Up 200; 5uM; MCF7; HT_HG-U133A

WSB1 TNFRSF25 ZNF862 CACNA1I MMP15 CDH2

7.06e-051988061465_UP
DrugMethionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; HL60; HT_HG-U133A

TNFRSF25 OLFML2B ZNF862 FGFR2 MMP3 CCDC70

7.26e-051998062470_UP
DrugDelcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A

OLFML2A USP2 TNFRSF25 ZNF862 CACNA1I MMP3

7.26e-051998066033_DN
DrugLinuron

IL1RAPL1 CACNA1A GRIA4 CACNA1I FGFR2

8.91e-05128805ctd:D008044
DiseaseMalignant neoplasm of breast

AKAP6 PIK3R4 ARID1B TBC1D9B MAGED2 SYNE1 COLGALT2 FGFR2 MMP3 ARID1A CDH2 NOS2 MRPS22 INPP4B NLRP8

2.03e-0710748115C0006142
DiseaseAutism Spectrum Disorders

IL1RAPL1 NLGN3 NLGN4X CHD2 FEV

3.80e-0685815C1510586
DiseaseBreast Carcinoma

ARID1B SYNE1 FGFR2 MMP3 ARID1A CDH2 NOS2 MRPS22 INPP4B

1.70e-05538819C0678222
DiseaseAntenatal Bartter syndrome

SLC12A1 MAGED2

2.23e-053812cv:CN239220
DiseaseBartter syndrome, antenatal type 1

SLC12A1 MAGED2

2.23e-053812C1866495
DiseaseIntrahepatic Cholangiocarcinoma

FGFR2 ARID1A NOS2

3.87e-0524813C0345905
DiseaseExtrahepatic Cholangiocarcinoma

FGFR2 ARID1A NOS2

3.87e-0524813C3805278
DiseaseCholangiocarcinoma

FGFR2 ARID1A NOS2

4.95e-0526813C0206698
Diseaseautism spectrum disorder (implicated_via_orthology)

NLGN3 ARID1B NLGN4X NLGN4Y CHD2

6.35e-05152815DOID:0060041 (implicated_via_orthology)
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1B ARID1A

7.40e-055812C3281201
DiseaseBartter syndrome

SLC12A1 MAGED2

1.11e-046812cv:C0004775
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1B ARID1A INPP4B

1.97e-0441813C0496956
DiseaseBreast adenocarcinoma

ARID1B ARID1A INPP4B

1.97e-0441813C0858252
Diseaseneuroblastoma (is_implicated_in)

ARID1B ARID1A

3.30e-0410812DOID:769 (is_implicated_in)
DiseaseLiver carcinoma

OLFML2A USP2 ARID1B OLFML2B ARID1A INPP4B FABP5

4.93e-04507817C2239176
Diseasecognitive function measurement

AKAP6 IL1RAPL1 ARID1B HEATR4 GRIA4 CACNA1I CHD2 CDH2 CDH4 IQCM CDH7 CDH9

5.24e-0414348112EFO_0008354
DiseaseCoffin-Siris syndrome

ARID1B ARID1A

5.69e-0413812C0265338
Diseaseabdominal aortic aneurysm (biomarker_via_orthology)

MMP3 NOS2

6.63e-0414812DOID:7693 (biomarker_via_orthology)
DiseaseAutistic Disorder

IL1RAPL1 NLGN3 NLGN4X NOS2 CDH9

7.72e-04261815C0004352
Diseaseresponse to methotrexate

CDH9 INPP4B

8.71e-0416812GO_0031427
Diseasematrix metalloproteinase 12 measurement

GRIA4 MMP3

1.11e-0318812EFO_0010590
Diseasebehavioural disinhibition measurement

CACNA1I CDH9 DNAH11

1.17e-0375813EFO_0006946
Diseasecitrate measurement

IL1RAPL1 NLGN4X CDH2

1.36e-0379813EFO_0010114
DiseaseX-24309 measurement

DNAJC13 HEATR4

1.37e-0320812EFO_0800872
DiseaseNasopharyngeal carcinoma

SYNE1 ARID1A

1.66e-0322812C2931822
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

FGFR2 MMP3

1.81e-0323812DOID:0050156 (is_marker_for)
DiseaseCoronary heart disease

MMP3 DNAH11

1.98e-0324812C0010068
Diseaseankylosing spondylitis

AKAP6 NOS2 KPNB1

2.03e-0391813EFO_0003898
Diseaserefractive error

AKAP6 USP2 GRIA4 CACNA1I CDH2

2.06e-03326815MONDO_0004892
DiseaseAbnormality of refraction

AKAP6 PIK3R4 DNAJC13 PHF19 GRIA4 CDH2 SNTB1

2.52e-03673817HP_0000539
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

ARID1A KPNB1 DNAH11

2.59e-0399813EFO_0004611, EFO_0007878
Diseaseprimary biliary cholangitis (biomarker_via_orthology)

MMP3 NOS2

2.69e-0328812DOID:12236 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KMKKDIYWDDSAARP

BEST3

331

Q8N1M1
DLYDDWMRAASLKEP

BARGIN

371

Q6ZT62
QFLDKMDDPDYWRTV

BOP1

171

Q14137
EMDPDERWKAAYTRH

CACNA1A

796

O00555
RWGERKSKPNMNYDK

FEV

86

Q99581
DFRVFDSWFKVDMKP

DNAH11

1101

Q96DT5
EPERKLWVDRYLTFM

ARID1B

1136

Q8NFD5
KIEDFREEMWTFRGK

CCDC70

61

Q6NSX1
PAKYAETMDREFRKW

DOT1L

191

Q8TEK3
FSYDDKWVSVMERPK

DET1

466

Q7L5Y6
MRHSKRTYCPDWDDK

CLK1

1

P49759
MPEEKKDTVYWEKRR

NFILZ

36

A0A5F9ZHS7
YEIMFAKREDWPKIE

IQCM

366

A0A1B0GVH7
GEPERKMWVDRYLAF

ARID1A

1016

O14497
KMWVDRYLAFTEEKA

ARID1A

1021

O14497
IYMPKEKRARFSELW

ANKAR

161

Q7Z5J8
VLEVAMEHPKYEWFR

NOS2

326

P35228
MEHPKYEWFRELELK

NOS2

331

P35228
KRAPYWTNTEKMEKR

FGFR2

151

P21802
MAPKAWKVLTDYYRS

PAPSS2

596

O95340
KDPKEWAAQYREAME

MAGED2

466

Q9UNF1
VEFILMFYRDKPIDW

MGAT4B

316

Q9UQ53
RRYKSNVMEKFFPIW

NLRP8

151

Q86W28
CKLYRFPTSDNKWMR

INPP4B

236

O15327
GTKYWKFDNERLRME

MMP15

531

P51511
DKYWRFDEKRNSMEP

MMP3

406

P08254
MDRWKKLDQREYPGS

GRIA4

276

P48058
FWKRLQYEMPFKRIE

IL1RAPL1

551

Q9NZN1
ARWMEKHGFERPKYF

PDPR

471

Q8NCN5
FIPDEKKDAMYWEKR

NFIL3

66

Q16649
VDTVFRFDPRYNKWM

KLHL9

366

Q9P2J3
PEEARDWLYFEKFKM

HSPA12B

131

Q96MM6
WRLVDSKGFDEYMKE

FABP5

11

Q01469
RETIKFMYTDWADRD

NLGN3

451

Q9NZ94
LRETIKFMYTDWADK

NLGN4Y

416

Q8NFZ3
RLDMPEVLWKSYIDF

CRNKL1

671

Q9BZJ0
EMELAIFEKWKEYRG

EPB41L5

196

Q9HCM4
PRWDGNEMAKRAKAY

BABAM2

351

Q9NXR7
FKEERPEEYESWREM

ELOA

641

Q14241
ELSKDMRPFFEEYWA

ELOVL3

21

Q9HB03
ERIADVKKMWEEYPD

CHD2

91

O14647
RKMIDVYKPDWCEVR

CACNA1I

1131

Q9P0X4
EGKYPVRNDMELWKE

CYP27A1

121

Q02318
MQRDPYWKIKAFAIR

HEATR4

771

Q86WZ0
LNDWGPRFKKLADMY

CDH4

896

P55283
PDMKRESEKEWYFGN

DNAJC13

966

O75165
KNPDWRYRDAAVMAF

KPNB1

376

Q14974
YLSDWGPRFKKLADM

CDH6

766

P55285
YLSDWGPRFKRLADM

CDH7

761

Q9ULB5
ERLDYPKSRMAIWAA

COLGALT2

76

Q8IYK4
LVELPYKRSEMKEDW

CEP295

286

Q9C0D2
YLSDWGPRFKKLADM

CDH9

766

Q9ULB4
LRETIKFMYTDWADK

NLGN4X

416

Q8N0W4
YLNDWGPRFKKLADM

CDH2

886

P19022
VAYLPDYRMKEWSRR

NDUFB11

106

Q9NX14
GAWMKDPAARDDRIY

OLFML2A

416

Q68BL7
WEERDRMIQVYFPKE

MRPS22

186

P82650
YDSMPRRKEAWFSPV

SNTB1

356

Q13884
YRKLMEDPDKWKDYT

SYNE1

1116

Q8NF91
WALFYPKRAMDQARE

PIWIL2

606

Q8TC59
PDMKRYLWERYREAK

NT5DC3

51

Q86UY8
GAVDEPYDRRFVKWM

KYAT1

356

Q16773
RHEYPLSWMKEKIFS

SIRT2

201

Q8IXJ6
GMDFDSKKAYRDVAW

SIRT2

306

Q8IXJ6
ESWKVFEEMIEPYRL

SLC12A1

986

Q13621
YDFMERLDGKEKWSV

TENM2

506

Q9NT68
AWMKDPLAKDERIYV

OLFML2B

516

Q68BL8
PDYRHYLRMWAKEKE

TBC1D9B

996

Q66K14
WSYSEMEKEFPELIR

AKAP6

256

Q13023
WFMRADDDVYIKGDK

CHSY3

256

Q70JA7
SDMKIRFWDLAYPER

PIK3R4

1261

Q99570
YEWVHKPREMDTSRR

RPF1

331

Q9H9Y2
EEKFEASRGWFMRFK

TIGD1

126

Q96MW7
FYWKKMPSRTFIARE

TIGD1

191

Q96MW7
EKMAEPEKLTARVYW

SRPX2

191

O60687
RRYADYRHPDMWKND

SPRED1

256

Q7Z699
AYMPLRAKRWAAELD

PHF19

481

Q5T6S3
KERLKWKSDYPMTDG

UBTD1

31

Q9HAC8
YDVMDAVPARRWKEF

TNFRSF25

336

Q93038
DTWREKRDYVPDRMD

YLPM1

1381

P49750
YFTREEWGMLDKRQK

ZNF862

341

O60290
WNKYDDRLMKAAERG

UACA

31

Q9BZF9
WFPERDEYVAHMKKE

ZNF687

971

Q8N1G0
DDKMVRFWRIDEDYP

WSB1

331

Q9Y6I7
PDDEKGRQMWRKYLE

USP2

391

O75604
SKMWRDDREQFYKIA

UBE2G2

141

P60604
YPLIFDREKWRKMSS

WDR64

946

B1ANS9