Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF224 RREB1 ZNF251 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 NFX1 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	1.66e-18	1459	120	42	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF224 RREB1 ZNF251 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 NFX1 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B ZNF606 ZNF418 ZNF709 ZNF415 ZNF554	3.60e-18	1412	120	41	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF689 ZNF521 ZKSCAN2 ZNF224 RREB1 ZNF251 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZBTB39 ZSCAN10 ZNF334 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF415	3.38e-14	1244	120	34	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF689 ZNF521 ZKSCAN2 ZNF224 RREB1 ZNF251 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZBTB39 ZSCAN10 ZNF334 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF415	6.28e-14	1271	120	34	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF695 ZNF670 ZNF224 ZNF14 ZNF263 ZBTB39 NFX1 ZNF418 ZNF709	1.58e-04	326	120	9	GO:0001217
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF695 ZNF670 ZNF224 ZNF14 ZNF263 ZBTB39 NFX1 ZNF709	7.08e-04	320	120	8	GO:0001227
GeneOntologyMolecularFunction	glutamate-gated calcium ion channel activity	GRIN2C GRIN2D	9.79e-04	8	120	2	GO:0022849
GeneOntologyMolecularFunction	NMDA glutamate receptor activity	GRIN2C GRIN2D	9.79e-04	8	120	2	GO:0004972
Domain	ZINC_FINGER_C2H2_2	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 HELZ2 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B TRMT1L ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	1.49e-33	775	121	47	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 HELZ2 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B TRMT1L ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	1.67e-33	777	121	47	PS00028
Domain	ZnF_C2H2	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 HELZ2 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B TRMT1L ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	9.82e-33	808	121	47	SM00355
Domain	Znf_C2H2/integrase_DNA-bd	ZNF502 ZNF132 ZNF695 ZNF670 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	4.56e-32	694	121	44	IPR013087
Domain	Znf_C2H2-like	ZNF502 ZNF132 ZNF695 ZNF670 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 HELZ2 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B TRMT1L ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	7.45e-32	796	121	46	IPR015880
Domain	Znf_C2H2	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B TRMT1L ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	1.22e-31	805	121	46	IPR007087
Domain	-	ZNF502 ZNF132 ZNF695 ZNF670 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	2.87e-31	679	121	43	3.30.160.60
Domain	zf-C2H2	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	6.68e-31	693	121	43	PF00096
Domain	KRAB	ZNF132 ZNF695 ZNF670 ZNF460 ZNF875 ZNF689 ZKSCAN2 ZNF223 ZNF224 ZNF235 ZNF251 ZNF7 ZNF250 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZNF334 ZNF425 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF554	5.30e-29	358	121	33	PS50805
Domain	KRAB	ZNF132 ZNF695 ZNF670 ZNF460 ZNF875 ZNF689 ZKSCAN2 ZNF223 ZNF224 ZNF235 ZNF251 ZNF7 ZNF250 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZNF334 ZNF425 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF554	5.30e-29	358	121	33	PF01352
Domain	KRAB	ZNF132 ZNF695 ZNF670 ZNF460 ZNF875 ZNF689 ZKSCAN2 ZNF223 ZNF224 ZNF235 ZNF251 ZNF7 ZNF250 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZNF334 ZNF425 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF554	1.43e-28	369	121	33	SM00349
Domain	KRAB	ZNF132 ZNF695 ZNF670 ZNF460 ZNF875 ZNF689 ZKSCAN2 ZNF223 ZNF224 ZNF235 ZNF251 ZNF7 ZNF250 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZNF334 ZNF425 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF554	1.57e-28	370	121	33	IPR001909
Domain	zf-C2H2_6	ZNF502 ZNF695 ZNF670 ZNF521 ZNF224 RREB1 ZNF251 ZNF250 ZNF771 ZNF14 ZNF17 ZNF20 ZSCAN10 ZNF334 ZNF425 ZNF790 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF554	6.67e-23	314	121	27	PF13912
Domain	Retrov_capsid_C	PGBD1 ZKSCAN2 ADAMTS10 ZNF263 ZSCAN10	3.98e-05	59	121	5	IPR008916
Domain	Znf_FYVE-rel	PLEKHF1 PIKFYVE RIMS1 WDFY3	6.69e-05	34	121	4	IPR017455
Domain	Znf_FYVE	PLEKHF1 PIKFYVE RIMS1 WDFY3	1.04e-04	38	121	4	IPR000306
Domain	ZF_FYVE	PLEKHF1 PIKFYVE RIMS1 WDFY3	1.28e-04	40	121	4	PS50178
Domain	SCAN	PGBD1 ZKSCAN2 ZNF263 ZSCAN10	4.75e-04	56	121	4	SM00431
Domain	SCAN_BOX	PGBD1 ZKSCAN2 ZNF263 ZSCAN10	5.43e-04	58	121	4	PS50804
Domain	SCAN	PGBD1 ZKSCAN2 ZNF263 ZSCAN10	5.43e-04	58	121	4	PF02023
Domain	SCAN_dom	PGBD1 ZKSCAN2 ZNF263 ZSCAN10	5.43e-04	58	121	4	IPR003309
Domain	Znf_RING/FYVE/PHD	RBBP6 PLEKHF1 ZNF521 RNF17 TRIM27 PIKFYVE NEURL3 SH3RF2 RIMS1 WDFY3	8.11e-04	459	121	10	IPR013083
Domain	FYVE	PLEKHF1 PIKFYVE WDFY3	8.57e-04	29	121	3	PF01363
Domain	FYVE	PLEKHF1 PIKFYVE WDFY3	8.57e-04	29	121	3	SM00064
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF670 ZNF678 ZNF460 ZNF875 ZNF689 ZNF521 PSMC5 ZNF223 ZNF224 ZNF235 ZNF250 ZNF771 ZNF14 ZNF430 BMP2 ZNF17 ZNF263 ZNF20 AGO3 ZNF334 ZNF425 ZNF790 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	3.60e-11	1387	95	33	M734
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	DLGAP2 NTRK3 NLGN1 GRIN2C GRIN2D	8.68e-05	67	95	5	MM15327
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF670 ZNF678 ZNF460 ZNF689 ZNF235 ZNF7 ZNF250 ZNF430 ZNF17 ZNF20 ZNF778 ZNF749 ZNF564 ZNF554	3.37e-15	181	122	14	37372979
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF695 ZNF670 ZNF7 ZNF263 ZNF778 ZNF616	2.03e-08	49	122	6	9630514
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF224 ZNF7 ZNF14 ZNF17 ZNF20	7.72e-08	31	122	5	2288909
Pubmed	Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.	ZNF14 ZNF20 ZNF79	4.19e-07	5	122	3	8262519
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	VLDLR RBBP6 ZNF460 ZNF618 CHAF1A ZKSCAN2 RREB1 EZH1 TRIM27 REPIN1 TUBGCP6 ZNF771 AGO3 KMT5B WDFY3	8.96e-06	1116	122	15	31753913
Pubmed	Soluble receptor (DcR3) and cellular inhibitor of apoptosis-2 (cIAP-2) protect human cytotrophoblast cells against LIGHT-mediated apoptosis.	TNFSF14 TNFRSF6B	1.22e-05	2	122	2	15215185
Pubmed	In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.	GRIN2C GRIN2D	1.22e-05	2	122	2	29651654
Pubmed	A TNF family member LIGHT transduces costimulatory signals into human T cells.	TNFSF14 TNFRSF6B	1.22e-05	2	122	2	12471113
Pubmed	Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.	GRIN2C GRIN2D	1.22e-05	2	122	2	31110197
Pubmed	Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.	GRIN2C GRIN2D	1.22e-05	2	122	2	35057644
Pubmed	NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.	GRIN2C GRIN2D	1.22e-05	2	122	2	31786200
Pubmed	Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.	TNFSF14 TNFRSF6B	1.22e-05	2	122	2	25087510
Pubmed	Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.	GRIN2C GRIN2D	1.22e-05	2	122	2	29317596
Pubmed	NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.	GRIN2C GRIN2D	1.22e-05	2	122	2	33766086
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	EZH1 ZBTB39 RIMS1 HERC2 PRORP	3.41e-05	104	122	5	9205841
Pubmed	Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.	GRIN2C GRIN2D	3.65e-05	3	122	2	9718984
Pubmed	Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.	GRIN2C GRIN2D	3.65e-05	3	122	2	35867797
Pubmed	Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.	GRIN2C GRIN2D	3.65e-05	3	122	2	33421565
Pubmed	Decoy strategies: the structure of TL1A:DcR3 complex.	TNFSF14 TNFRSF6B	3.65e-05	3	122	2	21300286
Pubmed	Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model.	KMT5B WDFY3	3.65e-05	3	122	2	30564305
Pubmed	Modulation of dendritic cell differentiation and maturation by decoy receptor 3.	TNFSF14 TNFRSF6B	3.65e-05	3	122	2	11994433
Pubmed	Site-specific regulation of Th2 differentiation within lymph node microenvironments.	ICAM1 IL4	3.65e-05	3	122	2	38442268
Pubmed	Modulation of T-cell responses to alloantigens by TR6/DcR3.	TNFSF14 TNFRSF6B	3.65e-05	3	122	2	11390428
Pubmed	Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin.	HJV BMP2	3.65e-05	3	122	2	18287331
Pubmed	Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2- and BMP6-mediated signaling and gene expression.	HJV BMP2	3.65e-05	3	122	2	20530805
Pubmed	The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV.	ZNF14 ZNF709	3.65e-05	3	122	2	30709743
Pubmed	Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.	GRIN2C GRIN2D	3.65e-05	3	122	2	9480759
Pubmed	Multidimensional genome scans identify the combinations of genetic loci linked to diabetes-related phenotypes in mice.	ZNF235 TBC1D1	3.65e-05	3	122	2	16321990
Pubmed	Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains.	HJV BMP2	3.65e-05	3	122	2	18335997
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF223 ZNF224 ZNF235	4.60e-05	20	122	3	12743021
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF618 LCMT2 PIKFYVE ZBTB39 HELZ2 ZNF616 ZNF518B PRORP ZNF606	6.36e-05	493	122	9	15368895
Pubmed	Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.	GRIN2C GRIN2D	7.29e-05	4	122	2	8699248
Pubmed	Role of non-HLA genetic variants in end-stage renal disease.	ICAM1 IL4	7.29e-05	4	122	2	19497039
Pubmed	Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes.	TNFSF14 TNFRSF6B	7.29e-05	4	122	2	12466117
Pubmed	Differential cellular expression of LIGHT and its receptors in early gestation human placentas.	TNFSF14 TNFRSF6B	7.29e-05	4	122	2	17010447
Pubmed	Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.	GRIN2C GRIN2D	7.29e-05	4	122	2	9768843
Pubmed	Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.	GRIN2C GRIN2D	7.29e-05	4	122	2	36309015
Pubmed	Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.	GRIN2C GRIN2D	1.21e-04	5	122	2	26919761
Pubmed	Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.	GRIN2C GRIN2D	1.21e-04	5	122	2	7518475
Pubmed	Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.	GRIN2C GRIN2D	1.21e-04	5	122	2	7518474
Pubmed	Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.	GRIN2C GRIN2D	1.21e-04	5	122	2	9147327
Pubmed	Neurotransmission and bipolar disorder: a systematic family-based association study.	GRIN2C GRIN2D	1.21e-04	5	122	2	18444252
Pubmed	Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.	GRIN2C GRIN2D	1.21e-04	5	122	2	8015722
Pubmed	Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.	GRIN2C GRIN2D	1.21e-04	5	122	2	15003177
Pubmed	GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.	GRIN2C GRIN2D	1.21e-04	5	122	2	7723623
Pubmed	Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.	GRIN2C GRIN2D	1.21e-04	5	122	2	12082569
Pubmed	Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.	GRIN2C GRIN2D	1.21e-04	5	122	2	21945132
Pubmed	Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.	GRIN2C GRIN2D	1.21e-04	5	122	2	11488959
Pubmed	Developmental changes in distribution of NMDA receptor channel subunit mRNAs.	GRIN2C GRIN2D	1.21e-04	5	122	2	1493227
Pubmed	N-methyl-D-aspartic acid receptor structure and function.	GRIN2C GRIN2D	1.21e-04	5	122	2	8036251
Pubmed	NMDA receptor activation by HIV-Tat protein is clade dependent.	GRIN2C GRIN2D	1.21e-04	5	122	2	19020013
Pubmed	Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.	GRIN2C GRIN2D	1.21e-04	5	122	2	26875626
Pubmed	Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.	GRIN2C GRIN2D	1.21e-04	5	122	2	7510577
Pubmed	Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.	GRIN2C GRIN2D	1.21e-04	5	122	2	8756432
Pubmed	Retinoic acid inhibits CD40 plus IL-4 mediated IgE production through alterations of sCD23, sCD54 and IL-6 production.	ICAM1 IL4	1.21e-04	5	122	2	15883744
Pubmed	Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.	GRIN2C GRIN2D	1.21e-04	5	122	2	18233995
Pubmed	Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.	GRIN2C GRIN2D	1.21e-04	5	122	2	7929904
Pubmed	A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.	GRIN2C GRIN2D	1.81e-04	6	122	2	23665428
Pubmed	Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.	HJV BMP2	1.81e-04	6	122	2	16604073
Pubmed	Altered gene expression of the N-methyl-D-aspartate receptor channel subunits in Purkinje cells of the staggerer mutant mouse.	GRIN2C GRIN2D	1.81e-04	6	122	2	8996814
Pubmed	Monitoring cell physiology by expression profiles and discovering cell type-specific genes by compiled expression profiles.	PRSS57 ZNF263	1.81e-04	6	122	2	8586417
Pubmed	Chromosomal location of three unconventional myosin heavy chain genes in the mouse.	CYP1A2 NCAN	1.81e-04	6	122	2	8954808
Pubmed	NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit.	GRIN2C GRIN2D	1.81e-04	6	122	2	15317856
Pubmed	Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.	GRIN2C GRIN2D	1.81e-04	6	122	2	25760043
Pubmed	A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis.	TNFSF14 TNFRSF6B	1.81e-04	6	122	2	10318773
Pubmed	Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.	GRIN2C GRIN2D	1.81e-04	6	122	2	9458051
Pubmed	Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein.	HJV BMP2	1.81e-04	6	122	2	25938661
Pubmed	PSMC3 promotes RNAi by maintaining AGO2 stability through USP14.	RBBP6 ZNF415	1.81e-04	6	122	2	36528617
Pubmed	Role of Tat protein in HIV neuropathogenesis.	ICAM1 GRIN2C GRIN2D	2.13e-04	33	122	3	19526283
Pubmed	Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study.	ICAM1 IL4	2.53e-04	7	122	2	16184405
Pubmed	HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.	GRIN2C GRIN2D	2.53e-04	7	122	2	22940423
Pubmed	Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.	GRIN2C GRIN2D	2.53e-04	7	122	2	12103442
Pubmed	Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.	GRIN2C GRIN2D	2.53e-04	7	122	2	23267846
Pubmed	Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.	ZNF223 ZNF235	2.53e-04	7	122	2	8617494
Pubmed	Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.	GRIN2C GRIN2D	2.53e-04	7	122	2	19036954
Pubmed	Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.	GRIN2C GRIN2D	2.53e-04	7	122	2	22833210
Pubmed	Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice.	KMT5B WDFY3	2.53e-04	7	122	2	36897941
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	RBBP6 HERC2	2.53e-04	7	122	2	36700049
Pubmed	Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.	GRIN2C GRIN2D	3.37e-04	8	122	2	8804048
Pubmed	The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.	GRIN2C GRIN2D	3.37e-04	8	122	2	8845955
Pubmed	HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.	GRIN2C GRIN2D	3.37e-04	8	122	2	8563977
Pubmed	HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.	GRIN2C GRIN2D	3.37e-04	8	122	2	8821747
Pubmed	Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.	GRIN2C GRIN2D	3.37e-04	8	122	2	7695237
Pubmed	HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.	GRIN2C GRIN2D	3.37e-04	8	122	2	17360663
Pubmed	Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.	GRIN2C GRIN2D	3.37e-04	8	122	2	8724036
Pubmed	Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.	GRIN2C GRIN2D	3.37e-04	8	122	2	8822372
Pubmed	Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production.	GRIN2C GRIN2D	3.37e-04	8	122	2	21106831
Pubmed	Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.	GRIN2C GRIN2D	3.37e-04	8	122	2	10448428
Pubmed	Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.	GRIN2C GRIN2D	3.37e-04	8	122	2	8955056
Pubmed	Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.	GRIN2C GRIN2D	3.37e-04	8	122	2	10555109
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	EPHB6 ZNF695 ZNF689 OBSCN ZNF224 REPIN1 TUBGCP6 ADAMTS10 ZSCAN10 NCAN ZNF808 HERC2 ZNF415	3.51e-04	1215	122	13	15146197
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZNF678 ZNF460 ZNF689 CHAF1A PSMC5 RREB1 EZH1 ZNF518B	3.72e-04	495	122	8	27705803
Pubmed	The zinc finger-associated SCAN box is a conserved oligomerization domain.	ZNF20 ZNF79	4.32e-04	9	122	2	10567577
Pubmed	D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.	GRIN2C GRIN2D	4.32e-04	9	122	2	22552781
Pubmed	Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.	GRIN2C GRIN2D	4.32e-04	9	122	2	21670103
Pubmed	BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.	HJV BMP2	4.32e-04	9	122	2	19252486
Pubmed	Dynamin genes Dnm1 and Dnm2 are located on proximal mouse chromosomes 2 and 9, respectively.	CYP1A2 ICAM1	4.32e-04	9	122	2	9143510
Pubmed	PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.	GRIN2C GRIN2D	4.32e-04	9	122	2	9892651
Pubmed	Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems.	GRIN2C GRIN2D	4.32e-04	9	122	2	17526495
Pubmed	Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.	GRIN2C GRIN2D	4.32e-04	9	122	2	21491143
Interaction	LTBP2 interactions	ZKSCAN2 ZNF251 REPIN1 ZNF430 ZNF17 ZNF263 ZNF778 ZNF749 ZNF564 ZNF709	6.96e-11	85	118	10	int:LTBP2
Interaction	NOTCH2 interactions	ZNF460 NTRK3 ZNF689 ZKSCAN2 ZNF235 REPIN1 CACNG3 ZNF7 ZNF771 ZNF430 CFD ZNF263 ZBTB39 ZNF761 ZNF709	2.66e-08	423	118	15	int:NOTCH2
Interaction	TRIM28 interactions	ZNF695 ZNF670 ZNF678 ZNF460 ZNF689 CHAF1A PSMC5 ZNF223 ZNF224 ZNF235 ZNF7 ZNF250 ZNF14 ZNF430 CFD ZNF17 ZNF263 ZNF20 NFX1 ZNF808 ZNF778 ZNF616 ZNF749 ZNF761 ZNF418 ZNF564 ZNF554	8.08e-08	1474	118	27	int:TRIM28
Interaction	KRTAP10-7 interactions	ZNF670 ZNF223 LCE1A ZNF250 ZNF20 ZSCAN10 ZNF425 ZNF837 ZNF778 ZNF418 ZNF564	1.23e-06	293	118	11	int:KRTAP10-7
Interaction	TRIM41 interactions	ZNF670 ZNF460 ZNF223 ZNF251 ZNF250 ZNF263 ZBTB39 ZNF837 ZNF564	6.66e-06	223	118	9	int:TRIM41
Interaction	CCDC136 interactions	ZNF670 PSMC5 ZNF223 ZNF250 ZNF20 ZNF837 HERC2 ZNF564	6.93e-06	169	118	8	int:CCDC136
Interaction	CARD10 interactions	ZNF670 ZNF223 TRIM27 ZNF250 ZNF837 ZNF564 ZNF415	9.87e-06	127	118	7	int:CARD10
Interaction	CCNDBP1 interactions	ZNF670 ZNF223 ZNF20 NEURL3 ZNF334 ZNF837 ZNF564	1.62e-05	137	118	7	int:CCNDBP1
Interaction	TRIM39 interactions	EPHB6 ZNF460 ZNF689 ZNF223 ZNF17 WDFY3	4.17e-05	108	118	6	int:TRIM39
Interaction	MTCL2 interactions	ZNF460 ZNF689 SIRT7 ZNF263 ZNF20 HERC2	5.65e-05	114	118	6	int:MTCL2
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	KLK15 ZNF132 SRRM5 ZNF460 ZNF875 ZNF223 ZNF224 GRIN2D ZNF235 ZNF17 ZNF837 ZNF790 ZNF534 ZNF808 ZNF616 ZNF749 ZNF761 ZNF606 ZNF418 ZNF415	5.71e-11	1192	122	20	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	PRSS57 TNFSF14 CHAF1A ICAM1 IQCN NIBAN3 ADAMTS10 ZNF14 CFD ZNF20 NCAN ZNF564 ZNF709 ZNF554	3.06e-08	797	122	14	chr19p13
Cytoband	19q13.41	KLK15 ZNF534 ZNF808 ZNF616	5.82e-05	78	122	4	19q13.41
Cytoband	19q13.4	ZNF132 ZNF460 ZNF17 ZNF606	6.11e-05	79	122	4	19q13.4
Cytoband	19p13.3	PRSS57 TNFSF14 CHAF1A CFD ZNF554	4.46e-04	237	122	5	19p13.3
Cytoband	19q13.43	ZNF837 ZNF749 ZNF418	1.65e-03	87	122	3	19q13.43
Cytoband	16p12.1	ZKSCAN2 CACNG3	2.02e-03	25	122	2	16p12.1
Cytoband	1q44	ZNF695 ZNF670 TFB2M	3.21e-03	110	122	3	1q44
Cytoband	1p34	EDN2 AGO3	3.30e-03	32	122	2	1p34
Cytoband	19p13.2	ADAMTS10 ZNF20 ZNF564 ZNF709	3.35e-03	229	122	4	19p13.2
Cytoband	17q25	GRIN2C SIRT7	4.87e-03	39	122	2	17q25
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	ZNF695 ZNF670 TFB2M	4.91e-03	128	122	3	chr1q44
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF502 ZNF132 ZNF695 ZNF670 ZNF678 ZNF460 ZNF618 ZNF875 ZNF689 ZNF521 ZKSCAN2 ZNF223 ZNF224 ZNF235 RREB1 ZNF251 REPIN1 ZNF7 ZNF250 ZNF771 ZNF14 ZNF430 ZNF17 ZNF263 ZNF20 ZBTB39 ZSCAN10 ZNF334 ZNF425 ZNF837 ZNF790 ZNF534 ZNF808 ZNF778 ZNF616 ZNF79 ZNF749 ZNF761 ZNF518B ZNF606 ZNF418 ZNF564 ZNF709 ZNF415 ZNF554	1.85e-37	718	96	45	28
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN2C GRIN2D	5.76e-04	7	96	2	1201
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	PLEKHF1 PIKFYVE WDFY3	5.85e-04	31	96	3	81
GeneFamily	UPF1 like RNA helicases	MOV10L1 HELZ2	1.49e-03	11	96	2	1169
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VLDLR RNF17 NEURL3 ZNF334 SH3RF2 ZNF415	5.11e-06	159	122	6	1baf0eaf9684668146a63192e77eec6c3c7a37f8
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLEKHF1 PGBD1 TUBGCP6 BMP2 TRAPPC3 DCAF11	6.77e-06	167	122	6	f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCell	mild_COVID-19-HSPC\|mild_COVID-19 / disease group, cell group and cell class (v2)	PRSS57 ZNF521 C1orf167 ZNF334 ZNF534 ZNF418	7.00e-06	168	122	6	90b33962adb77d8326dee403712118398b4d1315
ToppCell	mild_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	PRSS57 ZNF521 C1orf167 ZNF334 ZNF534 ZNF418	7.49e-06	170	122	6	85c476e0bc496445e868a88849960598d97bdea2
Drug	Emetine dihydrochloride [316-42-7]; Up 200; 7.2uM; PC3; HT_HG-U133A	PLEKHF1 ICAM1 ZNF235 FRMD4B ZNF14 ZNF20 ZNF334 ZNF79 ZNF606	3.65e-07	174	120	9	4243_UP
Drug	Cephaeline dihydrochloride heptahydrate [6487-30-5]; Up 200; 6uM; PC3; HT_HG-U133A	PLEKHF1 ICAM1 TNFRSF6B EZH1 FRMD4B ZNF14 ZNF20 ZNF79 ZNF606	3.83e-07	175	120	9	4651_UP
Drug	ES-242-1	GRIN2C GRIN2D MOV10L1	7.84e-06	8	120	3	CID000131976
Disease	cytochrome p450 3a4 measurement	PIKFYVE CFD TRIB1	8.59e-06	11	112	3	EFO_0020303
Disease	HEMOCHROMATOSIS, TYPE 1	HJV BMP2	4.27e-05	3	112	2	C3469186
Disease	protein YIPF6 measurement	PIKFYVE CFD	4.27e-05	3	112	2	EFO_0802969
Disease	E3 ubiquitin-protein ligase RNF149 measurement	PIKFYVE CFD	8.53e-05	4	112	2	EFO_0802511
Disease	rap guanine nucleotide exchange factor 5 measurement	PIKFYVE CFD	8.53e-05	4	112	2	EFO_0802989
Disease	Schizophrenia	CYP1A2 DLGAP2 VLDLR RAPGEF6 NTRK3 ICAM1 PGBD1 NLGN1 GRIN2C GRIN2D NCAN IL4	1.36e-04	883	112	12	C0036341
Disease	zinc transporter 3 measurement	PIKFYVE CFD	1.42e-04	5	112	2	EFO_0803287
Disease	toll-like receptor 1 measurement	PIKFYVE CFD	1.42e-04	5	112	2	EFO_0803159
Disease	tachykinin-4 measurement	PIKFYVE CFD	1.42e-04	5	112	2	EFO_0803137
Disease	serine/threonine-protein kinase Chk1 measurement	PIKFYVE CFD	1.42e-04	5	112	2	EFO_0021965
Disease	activating signal cointegrator 1 complex subunit 1 measurement	PIKFYVE CFD	1.42e-04	5	112	2	EFO_0801340
Disease	membrane-associated progesterone receptor component 2 measurement	PIKFYVE CFD	1.42e-04	5	112	2	EFO_0801796
Disease	pre-mRNA-processing factor 6 measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0802894
Disease	E3 ubiquitin-protein ligase RNF128 measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0801555
Disease	thymidine kinase, cytosolic measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0020773
Disease	rab9 effector protein with kelch motifs measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0801984
Disease	o-acetyl-ADP-ribose deacetylase MACROD1 measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0802827
Disease	thioredoxin-interacting protein measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0803149
Disease	ribosome biogenesis protein TSR3 homolog measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0803025
Disease	CCAAT/enhancer-binding protein beta measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0021905
Disease	leucine-rich repeat and fibronectin type III domain-containing protein 1 measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0802689
Disease	leucine-rich repeat-containing protein 74A measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0801763
Disease	secreted frizzled-related protein 2 measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0802039
Disease	DNA-binding protein SATB2 measurement	PIKFYVE CFD	2.12e-04	6	112	2	EFO_0802484
Disease	autism spectrum disorder (implicated_via_orthology)	NLGN1 KMT5B SH3RF2 RIMS1 WDFY3	2.92e-04	152	112	5	DOID:0060041 (implicated_via_orthology)
Disease	Hereditary hemochromatosis	HJV BMP2	2.96e-04	7	112	2	cv:C0392514
Disease	myotubularin-related protein 1 measurement	PIKFYVE CFD	2.96e-04	7	112	2	EFO_0802773
Disease	kv channel-interacting protein 1 measurement	PIKFYVE CFD	2.96e-04	7	112	2	EFO_0801751
Disease	alpha-1-antichymotrypsin complex measurement	PIKFYVE CFD	2.96e-04	7	112	2	EFO_0008018
Disease	RNA polymerase II elongation factor ELL measurement	PIKFYVE CFD	2.96e-04	7	112	2	EFO_0802028
Disease	cytochrome c oxidase assembly factor 3 homolog, mitochondrial measurement	PIKFYVE CFD	3.94e-04	8	112	2	EFO_0801513
Disease	growth factor receptor-bound protein 7 measurement	PIKFYVE CFD	3.94e-04	8	112	2	EFO_0801659
Disease	tumor necrosis factor receptor superfamily member 19L measurement	PIKFYVE CFD	3.94e-04	8	112	2	EFO_0008309
Disease	cytochrome c oxidase subunit 4 isoform 2, mitochondrial measurement	PIKFYVE CFD	5.05e-04	9	112	2	EFO_0801514
Disease	RNA-binding protein 24 measurement	PIKFYVE CFD	5.05e-04	9	112	2	EFO_0802030
Disease	transcription factor IIIb 90 kda subunit measurement	PIKFYVE CFD	6.30e-04	10	112	2	EFO_0020778
Disease	DNA-directed RNA polymerases I and III subunit RPAC1 measurement	PIKFYVE CFD	6.30e-04	10	112	2	EFO_0801535
Disease	OCIA domain-containing protein 1 measurement	PIKFYVE CFD	6.30e-04	10	112	2	EFO_0008252
Disease	5-acetylamino-6-amino-3-methyluracil measurement	CYP1A2 CARNS1	7.68e-04	11	112	2	EFO_0800951
Disease	guanylate-binding protein 6 measurement	PIKFYVE CFD	7.68e-04	11	112	2	EFO_0801662
Disease	Hereditary hemochromatosis	HJV BMP2	9.19e-04	12	112	2	C0392514
Disease	Hemochromatosis	HJV BMP2	9.19e-04	12	112	2	C0018995
Disease	gout	ZKSCAN2 RREB1 FRMD4B PXDNL ZNF518B	9.28e-04	196	112	5	EFO_0004274
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	PIKFYVE CFD	1.08e-03	13	112	2	EFO_0802114
Disease	interleukin 12 measurement	VLDLR ZNF521 NFX1	1.09e-03	53	112	3	EFO_0004753
Disease	plasminogen activator inhibitor 1 measurement	MUC12 FRMD4B MOV10L1	1.15e-03	54	112	3	EFO_0004792
Disease	factor VII activating protease measurement	RREB1 ZNF20 HELZ2	1.21e-03	55	112	3	EFO_0009368
Disease	glycerate measurement	ZSCAN10 HMCN1	1.45e-03	15	112	2	EFO_0021029
Disease	Uremia	ICAM1 BMP2	1.87e-03	17	112	2	C0041948
Disease	Non-alcoholic Fatty Liver Disease	CYP1A2 VLDLR IL4	2.42e-03	70	112	3	C0400966
Disease	Nonalcoholic Steatohepatitis	CYP1A2 VLDLR IL4	2.42e-03	70	112	3	C3241937
Disease	lung carcinoma	CYP1A2 DLGAP2 ZNF618 PGBD1 ZKSCAN2 TRIM27 RIMS1	2.47e-03	482	112	7	EFO_0001071
Disease	Autistic Disorder	DLGAP2 VLDLR NLGN1 RIMS1 IL4	3.24e-03	261	112	5	C0004352
Disease	spermatogenic failure (is_implicated_in)	IQCN MOV10L1	3.43e-03	23	112	2	DOID:0111910 (is_implicated_in)
Disease	nephrotic syndrome (biomarker_via_orthology)	VLDLR IL4	3.73e-03	24	112	2	DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAVAHHTDCTFIRVS	PSMC5	201	P62195
VHESCRGQVSRAHAS	C1orf167	1146	Q5SNV9
CVAASEFHRSRHNVI	CACNG3	121	O60359
CHEHFSRITRDLQGE	CARNS1	571	A5YM72
RHRCSPRSSVHSECV	DLGAP2	131	Q9P1A6
SSHAQGTHLRLRRCS	EDN2	36	P20800
RHHTRLFCADRTERV	AGO3	711	Q9H9G7
EFQEHCRRGLLSNHT	CHAF1A	756	Q13111
RAASRANTVRSFHHE	BMP2	101	P12643
CRQSILIHSRHFNRT	BBS12	226	Q6ZW61
RSVRCTSHTGQASHE	ADAMTS10	1026	Q9H324
RRTARTCRGDLAFHS	HJV	91	Q6ZVN8
HARCEHVQARLRFSI	CYP1A2	501	P05177
RTVSDHRCFQSCQAH	IQCN	1026	Q9H0B3
RHLCFSAATREAQHA	NIBAN3	201	Q86XR2
RATCNRRTHHDGAIT	CFD	176	P00746
GHTRFVCISDTHSRT	MPPED2	56	Q15777
RIRTSEGRHRAFQTC	OR10G7	226	Q8NGN6
NRTTSRRCHFALEHV	MOV10L1	636	Q9BXT6
SEVTCFFDHVTHRVR	MAN2A1	836	Q16706
ASQHFVHRDLATRNC	NTRK3	671	Q16288
RLCSHRRALGDHSQA	HERC2	1376	O95714
SGCLTRHAAREHRQN	KMT5B	506	Q4FZB7
AHCQSRFMRVRLGEH	KLK15	61	Q9H2R5
QHFSHRGLCVVEQRS	FAM214B	116	Q7L5A3
HQRERGLCHRGSFSL	DCAF11	136	Q8TEB1
RTRHTVRCGQAVSVH	NFX1	481	Q12986
RSRCNTHGHVSDASI	TUBGCP6	1236	Q96RT7
HDVHRRCSPQRTTTN	NLGN1	746	Q8N2Q7
TSRLNFCGSNRIHHF	OR12D2	161	P58182
SVVRRCVHRATGHEF	PHKG2	36	P15735
RSCYRSINRGRHHSE	RBBP6	526	Q7Z6E9
RCRNHREEGISFSET	PKD1L2	2251	Q7Z442
TCVARNAAGSAHRHV	HMCN1	3966	Q96RW7
AKRGRSAECLHTTRH	RIMS1	1026	Q86UR5
RGSARCQLSHEGHRA	OBSCN	3136	Q5VST9
QNITQRDHGRFTCHA	PXDNL	386	A1KZ92
EIQETCDAHHRGRSR	FRG2B	136	Q96QU4
FTTFRRRHHCRLCGQ	PIKFYVE	171	Q9Y2I7
QHCRQRSGSLESQSH	FRMD4B	686	Q9Y2L6
DTRCLGATAQQFHRH	IL4	86	P05112
SRTDIHCRHQGVNIT	HEATR5B	1131	Q9P2D3
EVTRCHIRFTFRHRS	DOCK5	521	Q9H7D0
RSHRHRLQSSGCCSQ	LCE1A	76	Q5T7P2
RRDHHGANFSCRTEL	ICAM1	176	P05362
RRELVQVQRSHCGHF	HELZ2	1856	Q9BYK8
RIHTSEGRHRAFQTC	OR10G9	226	Q8NGN4
GEGRHRAFSTCASHL	OR5F1	231	O95221
CTQTRFSALTRRHHC	PLEKHF1	161	Q96S99
HVARRHYGCNIVRTE	TRMT1L	411	Q7Z2T5
VVCDRSREHRGHSVL	TRIM27	116	P14373
SQDDSIVGTRHCRHS	RAPGEF6	701	Q8TEU7
RRLTRTFEACHVAGA	EPHB6	66	O15197
QRAHIRLHFSVRACS	EPHB6	101	O15197
EGFAQHHVATIRCRS	NCAN	1246	O14594
SAAHCFSHRDLRTGL	PRSS57	71	Q6UWY2
HCFGRRSATVIDHLR	TFB2M	326	Q9H5Q4
TERTALHRHQTGRTC	SIRT7	211	Q9NRC8
SSHTQEICRLRFRHF	PGBD1	36	Q96JS3
TLHSGNHCRFITRDL	PRORP	486	O15091
ICTERHRHVDCSGRN	OMG	31	P23515
CGRRFSQGSHLAAHR	REPIN1	436	Q9BWE0
RRNCSSAEDFDHHGR	SLX4IP	296	Q5VYV7
FRGCSELRQHERLHS	ZNF837	456	Q96EG3
RNCSLVRHLRTHTGE	ZNF837	486	Q96EG3
GRRVSRSSGHHCELQ	RNF17	36	Q9BXT8
SSCQSFRRHERTHTG	ZNF564	151	Q8TBZ8
ECGRAFSSNSHLVRH	ZNF132	631	P52740
GNVFNECSHLTRHRR	ZNF678	271	Q5SXM1
ECGRTFNRGSHLTRH	ZNF460	256	Q14592
TFSRTSSLTCHRRRH	ZNF761	446	Q86XN6
FRCASQLQIHERTHS	ZNF20	376	P17024
TCGHRFRNSSNLARH	ZSCAN10	611	Q96SZ4
QCGRSFSRNSHLLRH	ZSCAN10	701	Q96SZ4
QHRRIHTGEKTFRCE	ZNF695	341	Q8IW36
AFTVRCGLTRHVRTH	ZNF778	401	Q96MU6
CGHAFSARRSLIQHE	ZNF250	456	P15622
SDRSAFARHRRIHTG	ZNF616	531	Q08AN1
CFQTHVRAHRDTEAT	ZNF618	161	Q5T7W0
SFRLRSSLNRHCVVH	ZNF223	296	Q9UK11
RHQRVHTGERPFECS	ZNF749	371	O43361
CGRRFGHRSNLAEHA	ZNF771	236	Q7L3S4
EREHVSRALCIHTGR	TRIB1	101	Q96RU8
SGCSVRFSLTERRHH	WDFY3	3461	Q8IZQ1
CQSALNVHRRSHTGE	ZNF334	416	Q9HCZ1
ASDVRCHQRRGTHSR	SRRM5	106	B3KS81
FTRLGRSHRRQSCSV	TNFSF14	21	O43557
CVTFRTHRGLLRHNA	RREB1	241	Q92766
ARSNVGRCHDFRETA	TRAPPC3	61	O43617
HIRQVHCDLSGSRFG	ZNF521	531	Q96K83
GETHESHAVRLCRAR	SOGA1	396	O94964
IRHVDHFGFICRESS	TBC1D1	326	Q86TI0
RRRRHHIVSASCSNA	EZH1	361	Q92800
FSNRSSLVCHRRIHS	ZNF808	716	Q8N4W9
CGKVFSRNSHLARHR	ZNF534	596	Q76KX8
KCSRSFRIHERVHSG	ZNF709	626	Q8N972
LDTRGCIAHRRTTFH	NEURL3	31	Q96EH8
VCETHFQDRNSRVTH	ZBTB39	376	O15060
QHFSTSRGGHHCARR	nan	21	Q5VV11
ECGRAFNRSSHLTTH	ZNF430	321	Q9H8G1
CFRRSRSLANHRTTH	ZNF689	241	Q96CS4
RCGRAFTHSSNLVLH	ZNF251	241	Q9BRH9
RNSCLALHRRVHTGE	ZNF415	331	Q09FC8
FSCGSDLTRHQRIHT	ZNF790	291	Q6PG37
QSCSLLRHRRVHTGE	ZNF418	521	Q8TF45
RDCVSVRFHNLNHGT	ZSWIM3	31	Q96MP5
RCRSFLTQHQRIHTG	ZNF502	221	Q8TBZ5
FNNCTRFREHRRIHT	ZKSCAN2	896	Q63HK3
HRSGCHSGQQTDLRR	SH3RF2	691	Q8TEC5
ECGQGFSRQSHLIRH	ZNF875	611	P10072
GRHCRVSQFHLLSRD	LCMT2	381	O60294
SFCGRSRLNRHSMVH	ZNF224	296	Q9NZL3
CGRSFRRRAHLTEHT	ZNF425	531	Q6IV72
AFRCSSAFVRHQRLH	ZNF79	481	Q15937
RSTDLNIHCRVHTGE	ZNF235	386	Q14590
SFRCRSTLDTHQRIH	ZNF17	506	P17021
GCSSRLIRHQRTHTG	ZNF7	451	P17097
RCSRVLRVHERTHSG	ZNF670	291	Q9BS34
ERSFNCSSHLIAHRR	ZNF606	686	Q8WXB4
SFCGRDFIHHSSLNR	ZNF14	106	P17017
SSNSCRVHERTHIGE	ZNF14	346	P17017
HATHNRACRCRTGFF	TNFRSF6B	106	O95407
SERTRCQLGIRRHHV	ZNF518B	976	Q9C0D4
RTCRIHEISCGAHST	VLDLR	111	P98155
CGDSFSHSSNRIRHL	ZNF263	636	O14978
ECGRAFTHSSTLTRH	ZNF554	356	Q86TJ5
HFHRSAGELRCRNAL	MUC12	61	Q9UKN1
VRTGHCGRHLSASER	GRIN2C	1006	Q14957
HDCRAQNRTHRGESL	GRIN2D	346	O15399