Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside-diphosphate reductase activity	RRM2B RRM2	2.05e-04	3	166	2	GO:0061731
GeneOntologyMolecularFunction	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	RRM2B RRM2	2.05e-04	3	166	2	GO:0004748
GeneOntologyMolecularFunction	olfactory receptor activity	OR4C11 OR5D14 OR5K3 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 OR6C70 OR6K3	2.68e-04	431	166	12	GO:0004984
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC38A5 SLC9A2 SLC9A6	2.92e-04	16	166	3	GO:0015385
GeneOntologyMolecularFunction	G-protein activated inward rectifier potassium channel activity	KCNJ5 KCNJ6	4.08e-04	4	166	2	GO:0015467
GeneOntologyMolecularFunction	calcium-dependent protein serine/threonine phosphatase regulator activity	PPP3R1 PPP3R2	6.76e-04	5	166	2	GO:0008597
GeneOntologyMolecularFunction	lysophosphatidic acid receptor activity	LPAR3 LPAR6	6.76e-04	5	166	2	GO:0070915
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	RRM2B RRM2	6.76e-04	5	166	2	GO:0016728
GeneOntologyCellularComponent	migrasome	TIMM23B TIMM23 TSPAN4	3.71e-05	9	162	3	GO:0140494
GeneOntologyCellularComponent	ribonucleoside-diphosphate reductase complex	RRM2B RRM2	1.78e-04	3	162	2	GO:0005971
GeneOntologyCellularComponent	methionine adenosyltransferase complex	MAT2B MAT1A	1.78e-04	3	162	2	GO:0048269
GeneOntologyCellularComponent	RAVE complex	DMXL2 DMXL1	1.78e-04	3	162	2	GO:0043291
Domain	ARM-type_fold	PDS5B RAP1GDS1 USP9X UBR4 ARFGEF3 ELMO3 PIK3C3 ARID2 EIF4G2 ASPM ULK4 NUP188 FMNL1	7.37e-06	339	160	13	IPR016024
Domain	TPR-contain_dom	NCF2 IFIT1B TTC21B PRMT9 TANC1 TTC22 EMC2 EDRF1	4.57e-05	150	160	8	IPR013026
Domain	RNR-rel	RRM2B RRM2	7.29e-05	2	160	2	IPR012348
Domain	RNR_small_fam	RRM2B RRM2	7.29e-05	2	160	2	IPR000358
Domain	RNR_small	RRM2B RRM2	7.29e-05	2	160	2	IPR033909
Domain	Rav1p_C	DMXL2 DMXL1	7.29e-05	2	160	2	IPR022033
Domain	-	RRM2B RRM2	7.29e-05	2	160	2	1.10.620.20
Domain	RNR_small_AS	RRM2B RRM2	7.29e-05	2	160	2	IPR030475
Domain	Rav1p_C	DMXL2 DMXL1	7.29e-05	2	160	2	PF12234
Domain	Ribonuc_red_sm	RRM2B RRM2	7.29e-05	2	160	2	PF00268
Domain	RIBORED_SMALL	RRM2B RRM2	7.29e-05	2	160	2	PS00368
Domain	TPR_REGION	NCF2 IFIT1B TTC21B PRMT9 TANC1 TTC22 EMC2 EDRF1	8.96e-05	165	160	8	PS50293
Domain	TPR	NCF2 IFIT1B TTC21B PRMT9 TANC1 TTC22 EMC2 EDRF1	8.96e-05	165	160	8	PS50005
Domain	Olfact_rcpt	OR4C11 OR5D14 OR5K3 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 OR6C70 OR6K3	1.50e-04	393	160	12	IPR000725
Domain	TPR_repeat	NCF2 IFIT1B TTC21B PRMT9 TANC1 TTC22 EMC2	1.50e-04	133	160	7	IPR019734
Domain	-	NCF2 IFIT1B TTC21B PRMT9 TANC1 TTC22 EMC2 EDRF1	4.21e-04	207	160	8	1.25.40.10
Domain	-	GTF2IRD2B GTF2IRD2	4.33e-04	4	160	2	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2IRD2	4.33e-04	4	160	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	4.33e-04	4	160	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	4.33e-04	4	160	2	IPR004212
Domain	GPCR_Rhodpsn_7TM	LPAR3 OR4C11 OR5D14 OR5K3 GPR63 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 LPAR6 OR6C70 OR6K3	6.56e-04	670	160	15	IPR017452
Domain	Parvalbumin	PPP3R1 PPP3R2	7.17e-04	5	160	2	IPR008080
Domain	7tm_1	LPAR3 OR4C11 OR5D14 OR5K3 GPR63 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 LPAR6 OR6C70 OR6K3	7.30e-04	677	160	15	PF00001
Domain	G_PROTEIN_RECEP_F1_1	LPAR3 OR4C11 OR5D14 OR5K3 GPR63 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 LPAR6 OR6C70 OR6K3	8.22e-04	685	160	15	PS00237
Domain	TPR	NCF2 IFIT1B TTC21B TANC1 TTC22 EMC2	8.60e-04	129	160	6	SM00028
Domain	G_PROTEIN_RECEP_F1_2	LPAR3 OR4C11 OR5D14 OR5K3 GPR63 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 LPAR6 OR6C70 OR6K3	8.97e-04	691	160	15	PS50262
Domain	GPCR_Rhodpsn	LPAR3 OR4C11 OR5D14 OR5K3 GPR63 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR2M4 OR4C15 LPAR6 OR6C70 OR6K3	9.11e-04	692	160	15	IPR000276
Domain	TPR-like_helical_dom	NCF2 IFIT1B TTC21B PRMT9 TANC1 TTC22 EMC2 EDRF1	9.14e-04	233	160	8	IPR011990
Domain	ZnF_UBR1	UBR1 UBR4	1.49e-03	7	160	2	SM00396
Domain	ZF_UBR	UBR1 UBR4	1.49e-03	7	160	2	PS51157
Domain	zf-UBR	UBR1 UBR4	1.49e-03	7	160	2	PF02207
Domain	Znf_UBR	UBR1 UBR4	1.49e-03	7	160	2	IPR003126
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	DMXL2 USP45 UACA USP9X OTUD1 C2CD5 KIF7 OTULIN USP38	4.27e-08	147	167	9	29576527
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERBB2 UACA NACC1 TIMM23 DPF2 KANK2 DPM1 C2CD5 KIF7 INTS14 EML5 ARID2 BRPF1 AFG3L2 BRD7 ASPM TANC1 NUP188 CRYBG3 GARRE1	4.68e-07	1116	167	20	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DMXL2 MYH11 UACA ARHGAP39 ATP8B2 TBC1D9 C2CD5 LRIG2 SAMD9L ARID2 TTC21B EMC2 TMEM63A	8.60e-07	493	167	13	15368895
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR4C11 OR5D14 OR5K3 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR4C15 OR6C70 OR6K3	8.62e-07	340	167	11	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR4C11 OR5D14 OR5K3 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR4C15 OR6C70 OR6K3	8.62e-07	340	167	11	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR4C11 OR5D14 OR5K3 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR4C15 OR6C70 OR6K3	9.39e-07	343	167	11	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR4C11 OR5D14 OR5K3 OR8U3 OR5AR1 OR6P1 OR51G2 OR51E2 OR4C15 OR6C70 OR6K3	1.02e-06	346	167	11	14611657
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KRT14 USP9X ARFGEF3 CCNB2 ARID2 AFG3L2 RBM14 ASPM TANC1 CRYBG3 EIF3I CFAP44 GARRE1 ZMYM6	1.08e-06	588	167	14	38580884
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SELENOT CDK17 DMXL2 EAPP UACA MAT2B UBR4 ECHS1 KANK2 C2CD5 DMXL1 KIF7 SH3BP4 ITPR3 LRIG2 AFG3L2 EIF4G2 ASPM TANC1 CRYBG3 EMC2 EDRF1	2.88e-06	1487	167	22	33957083
Pubmed	A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk.	ERBB2 LRIG2 KDR	3.75e-06	7	167	3	20446891
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK17 ERBB2 RRM2 HDAC7 SH3BP4 ARFGEF3 FSIP2 PTPN3 PIK3C3 SYDE2 RBM14 TANC1 CRYBG3 EIF3I GARRE1 EDRF1	4.47e-06	861	167	16	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA3F PNPLA2 ERBB2 CDK12 TIMM23B UBR4 HECTD4 ATG2A ZNF236 HDAC7 TBC1D9 SH3BP4 ITPR3 RABL6 ULK4 TANC1 NUP188 PLXNA1	6.80e-06	1105	167	18	35748872
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB2 GPR63 LRP1B ITPR3 CD200R1L IL23R	9.74e-06	101	167	6	23382219
Pubmed	Mitocytosis, a migrasome-mediated mitochondrial quality-control process.	TIMM23B TIMM23 TSPAN4	1.27e-05	10	167	3	34048705
Pubmed	CDK12 and HER2 coamplification in two urothelial carcinomas with rapid and aggressive clinical progression.	ERBB2 CDK12	2.29e-05	2	167	2	33038052
Pubmed	Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells.	ESR2 PAOX	2.29e-05	2	167	2	35886868
Pubmed	Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway.	ERBB2 ESR2	2.29e-05	2	167	2	26709918
Pubmed	Significance of HER2 and VEGFR2 in Early-stage Endometrial Cancer.	ERBB2 KDR	2.29e-05	2	167	2	35241527
Pubmed	Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse.	RRM2B RRM2	2.29e-05	2	167	2	15322079
Pubmed	Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.	BET1 SEC22A	2.29e-05	2	167	2	8621431
Pubmed	ERBB2-amplified lobular breast carcinoma exhibits concomitant CDK12 co-amplification associated with poor prognostic features.	ERBB2 CDK12	2.29e-05	2	167	2	38335502
Pubmed	Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics.	MAT2B MAT1A	2.29e-05	2	167	2	21813468
Pubmed	Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis.	RRM2B RRM2	2.29e-05	2	167	2	25878246
Pubmed	Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.	GRM1 AFG3L2	2.29e-05	2	167	2	25485680
Pubmed	Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma.	CACNA1D KCNJ5	2.29e-05	2	167	2	24866132
Pubmed	The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells.	KDR PLXNA1	2.29e-05	2	167	2	19176370
Pubmed	Co-expression of ER-beta and HER2 associated with poorer prognosis in primary breast cancer.	ERBB2 ESR2	2.29e-05	2	167	2	19480740
Pubmed	Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants.	GPR63 TTC21B	2.29e-05	2	167	2	31730647
Pubmed	Cellular and Genetic Causes of Idiopathic Hyperaldosteronism.	CACNA1D KCNJ5	2.29e-05	2	167	2	30354720
Pubmed	Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer.	RRM2B RRM2	2.29e-05	2	167	2	21965764
Pubmed	Hormonal regulation of mitochondrial Tim23 gene expression in the mouse mammary gland.	TIMM23B TIMM23	2.29e-05	2	167	2	11165051
Pubmed	Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2.	RRM2B RRM2	2.29e-05	2	167	2	20484015
Pubmed	Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults.	CACNA1D KCNJ5	2.29e-05	2	167	2	35779252
Pubmed	An alpha globin pseudogene is located within the mouse t complex.	TCP1 ITPR3	2.29e-05	2	167	2	6321339
Pubmed	Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse.	RRM2B RRM2	2.29e-05	2	167	2	36882565
Pubmed	Embryonic Lethality in Homozygous Human Her-2 Transgenic Mice Due to Disruption of the Pds5b Gene.	PDS5B ERBB2	2.29e-05	2	167	2	26334628
Pubmed	Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury.	CACNA1D KCNJ5	2.29e-05	2	167	2	37593151
Pubmed	Redox property of ribonucleotide reductase small subunit M2 and p53R2.	RRM2B RRM2	2.29e-05	2	167	2	19082948
Pubmed	Effect of Tim23 knockdown in vivo on mitochondrial protein import and retrograde signaling to the UPRmt in muscle.	TIMM23B TIMM23	2.29e-05	2	167	2	29949403
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	2.29e-05	2	167	2	15388857
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDS5B UBR1 UACA NACC1 CDK12 DPF2 ARHGAP39 HDAC7 TBC1D9 C2CD5 BRPF1 EIF4G2 RBM14 ARHGEF6	2.44e-05	774	167	14	15302935
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CDK12 SMCHD1 RRM2B UBR4 KANK2 ARFGEF3 SAMD9L FMNL1 REV1	6.72e-05	361	167	9	26167880
Pubmed	A vitamin D pathway gene-gene interaction affects low-density lipoprotein cholesterol levels.	GC RXRG	6.85e-05	3	167	2	27721113
Pubmed	Aldosterone-Producing Adenomas: Histopathology-Genotype Correlation and Identification of a Novel CACNA1D Mutation.	CACNA1D KCNJ5	6.85e-05	3	167	2	28584016
Pubmed	NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone.	CACNA1D KCNJ5	6.85e-05	3	167	2	28584012
Pubmed	Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.	RRM2B RRM2	6.85e-05	3	167	2	17486094
Pubmed	Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.	TIMM23B TIMM23	6.85e-05	3	167	2	12437925
Pubmed	Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.	MAT2B MAT1A	6.85e-05	3	167	2	23425511
Pubmed	The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling.	ESR2 GRM1	6.85e-05	3	167	2	24048848
Pubmed	Multiple species of mammalian S-adenosylmethionine synthetase. Partial purification and characterization.	MAT2B MAT1A	6.85e-05	3	167	2	7213623
Pubmed	Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice.	KCNJ5 KCNJ6	6.85e-05	3	167	2	12499858
Pubmed	Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease.	TIMM23B TIMM23	6.85e-05	3	167	2	30405116
Pubmed	SlitC-PlexinA1 mediates iterative inhibition for orderly passage of spinal commissural axons through the floor plate.	ROBO3 PLXNA1	6.85e-05	3	167	2	33345773
Pubmed	Structure and function study of the complex that synthesizes S-adenosylmethionine.	MAT2B MAT1A	6.85e-05	3	167	2	25075345
Pubmed	Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome.	ERBB2 ESR2	6.85e-05	3	167	2	26678909
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1D KCNJ5	6.85e-05	3	167	2	26831068
Pubmed	Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.	KCNJ5 KCNJ6	6.85e-05	3	167	2	21637918
Pubmed	Assessment of 25-Year Survival of Women With Estrogen Receptor-Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial.	ERBB2 ESR2	6.85e-05	3	167	2	34190995
Pubmed	Comparison of tyrosine kinase receptors HER2, EGFR, and VEGFR expression in micropapillary urothelial carcinoma with invasive urothelial carcinoma.	ERBB2 KDR	6.85e-05	3	167	2	25293577
Pubmed	The calcineurin B subunit induces TNF-related apoptosis-inducing ligand (TRAIL) expression via CD11b-NF-κB pathway in RAW264.7 macrophages.	PPP3R1 PPP3R2	6.85e-05	3	167	2	22197822
Pubmed	NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming.	TIMM23B TIMM23	6.85e-05	3	167	2	37044213
Pubmed	Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis.	RRM2B RRM2	6.85e-05	3	167	2	23552804
Pubmed	Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term follow-up.	ERBB2 KDR	6.85e-05	3	167	2	20135347
Pubmed	Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.	RRM2B RRM2	6.85e-05	3	167	2	18997010
Pubmed	In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.	RRM2B RRM2	6.85e-05	3	167	2	14729598
Pubmed	Mutant huntingtin does not cross the mitochondrial outer membrane.	TIMM23B TIMM23	6.85e-05	3	167	2	32821928
Pubmed	Development of renal failure in PargParp-1 null and Timm23 hypomorphic mice.	TIMM23B TIMM23	6.85e-05	3	167	2	31326434
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	6.85e-05	3	167	2	15100712
Pubmed	Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.	RRM2B RRM2	6.85e-05	3	167	2	16376858
Pubmed	eIF3i activity is critical for endothelial cells in tumor induced angiogenesis through regulating VEGFR and ERK translation.	KDR EIF3I	6.85e-05	3	167	2	28193911
Pubmed	Genetic variants in vitamin D signaling pathways and risk of gestational diabetes mellitus.	GC RXRG	6.85e-05	3	167	2	27636996
Pubmed	Methionine adenosyltransferase 2A regulates mouse zygotic genome activation and morula to blastocyst transition†.	MAT2B MAT1A	6.85e-05	3	167	2	30265288
Pubmed	CCNB2, TOP2A, and ASPM Reflect the Prognosis of Hepatocellular Carcinoma, as Determined by Weighted Gene Coexpression Network Analysis.	CCNB2 ASPM	6.85e-05	3	167	2	32685486
Pubmed	LRP1B, BRD2 and CACNA1D: new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia.	CACNA1D LRP1B	6.85e-05	3	167	2	26586120
Pubmed	A diversified set of testicular cell proteins specified by genes within the mouse t complex.	TCP1 ITPR3	6.85e-05	3	167	2	6684996
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TCP1 ATG2A RRM2 DCTD KANK2 LRP1B KIF7 CCNB2 BRPF1 EIF4G2 RBM14 TANC1 GARRE1 CNN2	6.93e-05	853	167	14	28718761
Pubmed	Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.	SEMA3F OR4C11 OR6P1	8.41e-05	18	167	3	20550939
Pubmed	Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.	DPF2 ARID2 BRD7	9.96e-05	19	167	3	25066234
Pubmed	BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.	DPF2 ARID2 BRD7	9.96e-05	19	167	3	18809673
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DMXL2 MYH11 CDK12 TBC1D9 PPP1R16B	1.25e-04	100	167	5	10048485
Pubmed	Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.	CACNA1D HECTD4 ULK4	1.36e-04	21	167	3	25249183
Pubmed	Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import.	TIMM23B TIMM23	1.37e-04	4	167	2	19111522
Pubmed	Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancer.	ERBB2 ESR2	1.37e-04	4	167	2	21152100
Pubmed	Co-expression of human Kir3 subunits can yield channels with different functional properties.	KCNJ5 KCNJ6	1.37e-04	4	167	2	10659995
Pubmed	The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix.	TIMM23B TIMM23	1.37e-04	4	167	2	10393182
Pubmed	A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.	UBR1 UBR4	1.37e-04	4	167	2	16055722
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	1.37e-04	4	167	2	23229069
Pubmed	Loss of retinoid X receptor gamma subunit impairs group 1 mGluR mediated electrophysiological responses and group 1 mGluR dependent behaviors.	GRM1 RXRG	1.37e-04	4	167	2	33692389
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	1.37e-04	4	167	2	22899722
Pubmed	Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.	KCNJ5 KCNJ6	1.37e-04	4	167	2	15142872
Pubmed	Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma.	CACNA1D KCNJ5	1.37e-04	4	167	2	26351028
Pubmed	Triple-negative phenotype is of adverse prognostic value in patients treated with dose-dense sequential adjuvant chemotherapy: a translational research analysis in the context of a Hellenic Cooperative Oncology Group (HeCOG) randomized phase III trial.	ERBB2 ESR2	1.37e-04	4	167	2	21901395
Pubmed	ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation.	ESR2 IL23R	1.37e-04	4	167	2	31849948
Pubmed	Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.	KCNJ5 KCNJ6	1.37e-04	4	167	2	7499385
Pubmed	Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells.	KCNJ5 KCNJ6	1.37e-04	4	167	2	8630252
Pubmed	Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity.	CLEC9A GC	1.37e-04	4	167	2	34081922
Pubmed	The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.	RRM2B RRM2	1.37e-04	4	167	2	14583450
Pubmed	Structural characterization of the mouse Girk genes.	KCNJ5 KCNJ6	1.37e-04	4	167	2	11891065
Pubmed	Distinct distribution and prognostic significance of molecular subtypes of breast cancer in Chinese women: a population-based cohort study.	ERBB2 ESR2	1.37e-04	4	167	2	21749714
Pubmed	Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines.	KCNJ5 KCNJ6	1.37e-04	4	167	2	16109170
Interaction	RAC2 interactions	PDS5B RAP1GDS1 BET1 USP9X NCF2 ARHGAP39 KANK2 HDAC7 C2CD5 SH3BP4 ITPR3 ELMO3 AFG3L2 EMC2 GARRE1 FMNL1 PLXNA1 ARHGEF6	5.45e-06	674	157	18	int:RAC2
Interaction	FBXO42 interactions	KRT14 USP9X ARFGEF3 CCNB2 ARID2 AFG3L2 ASPM TANC1 CRYBG3 CFAP44 GARRE1	6.12e-06	259	157	11	int:FBXO42
GeneFamily	Protein phosphatase 3 regulatory subunits\|EF-hand domain containing	PPP3R1 PPP3R2	4.59e-05	2	123	2	697
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	NCF2 IFIT1B TTC21B TANC1 TTC22 EMC2	1.35e-04	115	123	6	769
GeneFamily	Ankyrin repeat domain containing	UACA KANK2 ANKRD18B PPP1R16B ANKRD61 ANKMY2 ANKRD18A TANC1	2.52e-04	242	123	8	403
GeneFamily	Lysophosphatidic acid receptors	LPAR3 LPAR6	6.76e-04	6	123	2	205
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR1 UBR4	9.43e-04	7	123	2	785
Coexpression	GSE3982_DC_VS_MAC_UP	UBR4 NCF2 DPF2 ZNF236 CFB ELMO3 PPP1R16B CRYBG3 ARHGEF6	5.26e-06	200	165	9	M5458
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	UBR1 DMXL2 MYH11 ITPR3 CASD1 ASPM IL23R	4.15e-06	173	167	7	efb8072475000888efe088d00e870c56ffad4172
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TICRR DMXL2 OTUD1 VSIG4 RRM2 ATP6V0D2 CYB5R4	4.83e-06	177	167	7	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 MYH11 TSHZ2 SLC38A5 ROBO3	4.94e-06	66	167	5	57fd31a25addc48793d7975eadccf4c5a41a8b03
ToppCell	Mid-temporal_gyrus_(MTG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TSHZ2 GRM1 ANKRD18B PTPN3 CFAP44 CCDC171 PLXNA1	5.01e-06	178	167	7	ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA SAMD9L LPAR6 PPP1R16B KDR TANC1 GARRE1	5.80e-06	182	167	7	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TSHZ2 SMCHD1 ATP8B2 RTKN2 LPAR6 ANKRD18A TMEM63A	9.09e-06	195	167	7	22191d361af136942508f1553ff41a626ed982ad
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NACC1 VSIG4 ATG2A TBC1D9 C2CD5 KCNJ5 ATP6V0D2	1.04e-05	199	167	7	514dbf128b6832b1cbd65be023d4fe02400e8dec
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	TSHZ2 ATP8B2 ANKRD18B SAMD9L LPAR6 ANKRD18A TMEM63A	1.07e-05	200	167	7	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Striatum / BrainAtlas - Mouse McCarroll V32	CDK17 MAT2B RXRG PPP3R1 TTC22 ROBO3	1.89e-05	146	167	6	7b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GRM1 RXRG CAPS2 IL23R ARHGEF6 DEUP1	2.28e-05	151	167	6	090b067873740c282865e2d02cf47d5cb3dd7607
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INTS14 PPP1R16B KDR TANC1 CRYBG3 GARRE1	4.29e-05	169	167	6	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	SEMA3F ERBB2 KANK2 CFB KIF7 FSIP2	4.73e-05	172	167	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	UBR1 DMXL2 MYH11 CASD1 ASPM IL23R	5.05e-05	174	167	6	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC9A KANK2 SH3BP4 SRPX2 KDR ROBO3	5.21e-05	175	167	6	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	TICRR CLEC9A RRM2 CCNB2 ASPM ANKRD18A	5.21e-05	175	167	6	74800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCell	Influenza_Severe-Plasmablast\|World / Disease group and Cell class	TICRR SLC38A5 RRM2 ARFGEF3 EML5 CCNB2	5.21e-05	175	167	6	14df8fc6f6beae1be7b7bd5837546d1ac1239a6f
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMXL2 RRM2 CFB PTPN3 ATP6V0D2 DEUP1	5.38e-05	176	167	6	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TICRR CLEC9A RRM2 CCNB2 ASPM ANKRD18A	5.55e-05	177	167	6	26c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC9A KANK2 SH3BP4 KDR ROBO3 ELOVL6	5.73e-05	178	167	6	742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CLEC9A RRM2 HDAC7 PPP1R16B KDR GARRE1	5.91e-05	179	167	6	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MYH11 ESR2 SLC9A2 KCNJ5 PPP1R16B CRYBG3	5.91e-05	179	167	6	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA SAMD9L LPAR6 PPP1R16B KDR TANC1	6.28e-05	181	167	6	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK17 KRT14 MAT1A USP9X EIF4G2 KDR	6.48e-05	182	167	6	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1D LRP1B ABCA10 TBC1D9 SH3BP4 PTPN3	7.75e-05	188	167	6	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	15-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	MAT1A GC CFB IFIT1B SLC13A5 HSD17B2	7.75e-05	188	167	6	c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell	15-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	MAT1A GC CFB IFIT1B SLC13A5 HSD17B2	7.75e-05	188	167	6	2534684e4932c1255c24a26ca2277ac7af0a118b
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	CDK17 RRM2 ARFGEF3 ASPM PPP1R16B TANC1	7.75e-05	188	167	6	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RRM2 KANK2 ITPR3 CCNB2 CCDC171 DEUP1	8.21e-05	190	167	6	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SEMA3F CLEC9A HDAC7 PPP1R16B KDR GARRE1	8.21e-05	190	167	6	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SEMA3F CLEC9A HDAC7 PPP1R16B KDR GARRE1	8.21e-05	190	167	6	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RRM2B RRM2 DMXL1 GTF2IRD2B RBM14 ASPM	8.21e-05	190	167	6	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RRM2B RRM2 DMXL1 GTF2IRD2B RBM14 ASPM	8.70e-05	192	167	6	c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RRM2 KANK2 CCNB2 ASPM CCDC171 DEUP1	8.95e-05	193	167	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UACA TSHZ2 ESR2 ABCA10 SRPX2 TANC1	9.21e-05	194	167	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TICRR MYH11 RRM2 RTKN2 ASPM SLC9A6	9.21e-05	194	167	6	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 AK9 ANKRD18B ULK4 ANKRD18A CFAP44	9.21e-05	194	167	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UACA TSHZ2 ESR2 ABCA10 SRPX2 TANC1	9.21e-05	194	167	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 RRM2 TBC1D9 CCNB2 ASPM ATP6V0D2	9.47e-05	195	167	6	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	TSNAXIP1 MAT1A AK9 CAPS2 CFAP44 DEUP1	9.47e-05	195	167	6	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	343B-Myeloid-Dendritic\|343B / Donor, Lineage, Cell class and subclass (all cells)	CLEC9A OTUD1 NCF2 RRM2 CCNB2 ASPM	9.74e-05	196	167	6	fdb4f7e757b30b974ed3cd80c47beb4557a70845
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERBB2 TSHZ2 GK5 CFB ARFGEF3 PTPN3	9.74e-05	196	167	6	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	Sepsis-URO-Lymphocyte-T/NK-Treg\|URO / Disease, condition lineage and cell class	TSHZ2 ESR2 ABCA10 RTKN2 SLC13A5 GARRE1	9.74e-05	196	167	6	8812d7365fb2b33feff93782d60776e932499a43
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LPAR3 KRT14 TSHZ2 LPAR6 PRMT9 FMNL1	1.00e-04	197	167	6	d968d7d5608b175bb567ea3a315bf473ec3be459
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 AK9 ARHGAP39 ULK4 CAPS2 CFAP44	1.00e-04	197	167	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RRM2 RTKN2 PTPN3 CCNB2 ASPM DEUP1	1.00e-04	197	167	6	196eaecef7003ed83f323c1f157c6a3594650097
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TSNAXIP1 MAT1A AK9 CAPS2 CFAP44 DEUP1	1.06e-04	199	167	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F UACA SH3BP4 ASPM PPP1R16B	1.09e-04	125	167	5	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_only / Treatment groups by lineage, cell group, cell type	HECTD4 AK9 RRM2 ATP11B CCNB2 ASPM	1.09e-04	200	167	6	83c4181c083b364f0d3a89ae7a0504781fa9fa9f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TICRR RRM2B RRM2 RTKN2 CCNB2 ASPM	1.09e-04	200	167	6	c9479452ab8c51139522383f745f02171ebbd7e2
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_only / Treatment groups by lineage, cell group, cell type	HECTD4 AK9 RRM2 ATP11B CCNB2 ASPM	1.09e-04	200	167	6	f15baf287ec467664c23faa53fdea45257f7b9d0
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TSNAXIP1 MAT1A AK9 CAPS2 CFAP44 DEUP1	1.09e-04	200	167	6	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary\|LPS_only / Treatment groups by lineage, cell group, cell type	HECTD4 AK9 RRM2 ATP11B CCNB2 ASPM	1.09e-04	200	167	6	ce8281c9556a1f64f8ca8a029110077d4ef5b35e
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Transverse / Region, Cell class and subclass	DMXL2 VSIG4 NCF2 RRM2 CCNB2 ASPM	1.09e-04	200	167	6	f588d8889f351c797963616a3575fa43efd46b9a
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-Treg\|Int-URO / Disease, condition lineage and cell class	CACNA1D TSHZ2 ATP8B2 ANKRD18B RTKN2 ANKRD18A	1.09e-04	200	167	6	47f265336bc3b8052c0cac730ac9afd41cd8fc43
ToppCell	Transverse-(5)_Dendritic_cell-(52)_cycling_DCs\|Transverse / shred on region, Cell_type, and subtype	DMXL2 VSIG4 NCF2 RRM2 CCNB2 ASPM	1.09e-04	200	167	6	51e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TICRR RRM2B RRM2 RTKN2 CCNB2 ASPM	1.09e-04	200	167	6	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	(52)_cycling_DCs\|World / shred on Cell_type and subtype	DMXL2 CLEC9A VSIG4 RRM2 CCNB2 ASPM	1.12e-04	201	167	6	ad2d25d84345fdd593065516a05c5c2b5429eac0
Disease	Heart Block	CACNA1D KCNJ5	1.72e-04	4	159	2	C0018794
Disease	Auriculo-Ventricular Dissociation	CACNA1D KCNJ5	1.72e-04	4	159	2	C0004331
Disease	(N(1) + N(8))-acetylspermidine measurement	ECHS1 PAOX	4.27e-04	6	159	2	EFO_0800091
Disease	Sick Sinus Syndrome	CACNA1D KCNJ5	4.27e-04	6	159	2	C0037052
Disease	diastolic blood pressure, unipolar depression	HECTD4 EIF4G2 ULK4	5.60e-04	30	159	3	EFO_0003761, EFO_0006336
Disease	response to atorvastatin, Myalgia	SLC13A5 MYOM2	7.91e-04	8	159	2	EFO_0010124, HP_0003326
Disease	response to clopidogrel, response to acetylsalicylate, major adverse cardiovascular event measurement	ECHS1 MYOM2	1.01e-03	9	159	2	EFO_0020863, GO_1903492, GO_1903493
Disease	arthritis (is_implicated_in)	GC IL23R	1.01e-03	9	159	2	DOID:848 (is_implicated_in)
Disease	Graves' disease (is_implicated_in)	ESR2 GC IL23R	1.22e-03	39	159	3	DOID:12361 (is_implicated_in)
Disease	high grade glioma (is_marker_for)	BRD7 ASPM KDR	1.51e-03	42	159	3	DOID:3070 (is_marker_for)
Disease	Coffin-Siris syndrome	DPF2 ARID2	2.16e-03	13	159	2	C0265338
Disease	uveitis (is_implicated_in)	GC IL23R	2.16e-03	13	159	2	DOID:13141 (is_implicated_in)
Disease	ovary epithelial cancer (is_marker_for)	BRD7 ASPM	2.16e-03	13	159	2	DOID:2152 (is_marker_for)
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	DMXL2 GJB2	2.16e-03	13	159	2	C1846647
Disease	urinary bladder cancer (is_marker_for)	ERBB2 ESR2 RRM2 KDR	2.72e-03	107	159	4	DOID:11054 (is_marker_for)
Disease	interleukin 18 receptor 1 measurement	SLC9A2 IL23R	2.89e-03	15	159	2	EFO_0008178
Disease	Sinus Node Dysfunction (disorder)	CACNA1D KCNJ5	2.89e-03	15	159	2	C0428908
Disease	Keratoderma, Palmoplantar	KRT14 GJB2	3.29e-03	16	159	2	C4551675
Disease	neurofilament light chain measurement	DMXL1 OTULIN EIF4G2	3.63e-03	57	159	3	EFO_0009178
Disease	ulcerative colitis (is_implicated_in)	GC IL23R	3.72e-03	17	159	2	DOID:8577 (is_implicated_in)
Disease	Polydactyly	EVC2 USP9X KIF7 TTC21B	3.75e-03	117	159	4	C0152427
Disease	rheumatoid arthritis (is_implicated_in)	ESR2 NCF2 IL23R	3.81e-03	58	159	3	DOID:7148 (is_implicated_in)
Disease	Endometrial Neoplasms	SEMA3F ESR2 HSD17B2	3.81e-03	58	159	3	C0014170
Disease	colorectal cancer (is_implicated_in)	ESR2 LRP1B ARID2 KDR	4.23e-03	121	159	4	DOID:9256 (is_implicated_in)
Disease	Deaf Mutism	CACNA1D GJB2	5.14e-03	20	159	2	C4082305
Disease	Deafness, Acquired	CACNA1D GJB2	5.14e-03	20	159	2	C0751068
Disease	Hearing Loss, Extreme	CACNA1D GJB2	5.14e-03	20	159	2	C0086395
Disease	Complete Hearing Loss	CACNA1D GJB2	5.14e-03	20	159	2	C0581883
Disease	Bilateral Deafness	CACNA1D GJB2	5.14e-03	20	159	2	C3665473
Disease	Familial aplasia of the vermis	KIF7 TTC21B	5.14e-03	20	159	2	cv:C0431399
Disease	Prelingual Deafness	CACNA1D GJB2	5.14e-03	20	159	2	C0011052

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLRIMENYCLMATKQ	TTC21B	1121	Q7Z4L5
GSQTKLLCYMMLFSL	BET1	91	O15155
CMQIAKGMSYLEDVR	ERBB2	826	P04626
IKSFMKQLMEGLEYC	CDK12	836	Q9NYV4
IFMSQVMVQYGACEE	ARHGEF6	451	Q15052
TMYELACDVVAANKM	PRMT9	211	Q6P2P2
GYKKCLEMTINMLNA	ANKRD18A	706	Q8IVF6
YCMINTGTQMDLEVK	CAPS2	11	Q9BXY5
VFKMGEVYQMDAESC	CRYBG3	1591	Q68DQ2
FVIRCLEMKYGNEIM	ABCA10	1131	Q8WWZ4
LKDNFKLMCTNAMIY	BRD7	196	Q9NPI1
YTKEQLLDRMCMTLG	AFG3L2	616	Q9Y4W6
VVACQAMIKSFMDVY	CCDC171	1196	Q6TFL3
LQMAPNSYTAQCVKM	FAM47DP	296	A6NHR8
VLYMLTEMGDVACTK	ARID2	421	Q68CP9
YKKCLEMTINMLNAF	ANKRD18B	716	A2A2Z9
QYRAMFVMNCSINKE	EAPP	201	Q56P03
CEGYFLKNMMVLIEN	BTBD11	1046	A6QL63
YISNGELFQVLKMMV	PPP3R2	106	Q96LZ3
MMETLIAYGANVNCA	ANKRD61	216	A6NGH8
YISNGELFQVLKMMV	PPP3R1	106	P63098
SSLSKNIMMYACINA	DMXL2	556	Q8TDJ6
VMYDGFSMQRLVKCN	GJB2	156	P29033
KMYQRQCQAMEAGLS	DEUP1	256	Q05D60
IMMYACTKNVDLAIQ	DMXL1	546	Q9Y485
MFCGMKNGAIRVYVL	CFAP44	821	Q96MT7
KCVSKGYVFQMEMIV	DPM1	201	O60762
FLKDNMAYMCTSQQT	ASPM	396	Q8IZT6
QIGSCSGYMELMVKL	ATG2A	251	Q2TAZ0
VNIGYSCKMLTDDMT	ATP8B2	701	P98198
GTVMSCAVMKQFAFV	RBM14	26	Q96PK6
YTVCDVAMNIIMSKS	PDS5B	1066	Q9NTI5
VYKNCNGVVMMFDIT	RABL6	136	Q3YEC7
KEACELFKLIQMYMG	ARHGAP39	741	Q9C0H5
RAMMVQTSSQYKFVC	PTPN3	881	P26045
KQFGMMQSQIGYDIL	ITPR3	576	Q14573
NLVMADKSIFYFSCM	OR5D14	86	Q8NGL3
SIVNAFMVGCMFVKI	KCNJ5	176	P48544
YQMIDESQSLSLCGM	CFB	466	P00751
MSIMSNKVCYQLVFS	OR6C70	131	A6NIJ9
MAISLSKMYIEQNAC	OTUD1	466	Q5VV17
KAISMTGCILQMYFF	OR6K3	106	Q8NGY3
MKEQTGSICQYLVMR	PNPLA2	366	Q96AD5
YVTKTISFEGCMMQL	OR4C15	86	Q8NGM1
RMSCQGIESFLMYSV	LRP1B	1871	Q9NZR2
MMQICDTYNQKHSLF	MID1IP1	1	Q9NPA3
SGNEQMTKYEMACAI	MAT2B	251	Q9NZL9
EYLCVKAMILLNSSM	ESR2	396	Q92731
FNIGCMYTILKNMTE	NCF2	41	P19878
MAKQMEFLCNQAGYE	NAB1	371	Q13506
VMCFHVNGIVQKYEM	EDRF1	366	Q3B7T1
VNAFMVGCMFVKISQ	KCNJ6	181	P48051
YCMQLAQIQEMIGSV	KRT14	366	P02533
QKMVDSVYCNILQMS	FSIP2	4211	Q5CZC0
AMMCDIIYAGEKAQF	ECHS1	146	P30084
CMGGKQMTQNYSTIF	CD200R1L	21	Q6Q8B3
LFMLYCAIKQQMEKG	PLXNA1	1461	Q9UIW2
QYTILMNPKLCVFMT	OR2M4	131	Q96R27
LSMYVVAMFGNCIVV	OR51E2	31	Q9H255
KLACADMKANSIYGM	OR51G2	191	Q8NGK0
LLSQCEMNLMAKLSY	KIF7	1076	Q2M1P5
ALFLMVRYQCLKGNM	EVC2	316	Q86UK5
YGTMKKMICCFSQEN	LPAR3	301	Q9UBY5
LLCGEITSMAMVDYQ	MAT1A	66	Q00266
DLLCKISVMLFYTNM	LPAR6	86	P43657
CGNIMSMHNVKLFLY	CDK17	281	Q00537
MSKTLCIQMTAGAYL	OR5K3	136	A6NET4
ACMDTYMINLLLVSN	OR4C11	186	Q6IEV9
SGENQIMMTKVYIFL	TMEM63A	496	O94886
VETCMFMIKLPQYSS	HECTD4	3961	Q9Y4D8
QYFARMCSLMLSKEL	EIF4G2	276	P78344
KIVCAMQMSLQGAEF	PIPSL	771	A2A3N6
CMAYQGITQEKINEM	PPP1R16B	186	Q96T49
QKATCMKMGYEEVSQ	OTULIN	101	Q96BN8
SMMKLLFISQLSYCG	OR6P1	156	Q8NGX9
SQITQMLMGCVVNYL	ELOVL6	201	Q9H5J4
KFNEMYLDTVCLNMV	IDH3A	226	P50213
TTAMILMNVYCNKIL	CASD1	281	Q96PB1
TLYMCVGIMDRFLQV	CCNB2	186	O95067
MNKNSTDVKGCSMYV	DCTD	91	P32321
VFANAATSYIMCLMK	ARFGEF3	1346	Q5TH69
NIIMFSTDKQMGYQC	EIF3I	106	Q13347
KLYIMCMANLEELQS	INTS14	151	Q96SY0
MLQLMKEAGCYNGIT	GARRE1	371	O15063
MGLCYRAQMIQIKEA	IFIT1B	291	Q5T764
NEKLLTVFCGMLMNY	RAP1GDS1	151	P52306
IKYNSMVLICALMGS	RAP1GDS1	551	P52306
IFKMGMNISIYCQAA	IL23R	41	Q5VWK5
LVVNYCSELSDMKIM	CCDC183	196	Q5T5S1
FMGYLNMEDKTCEAI	ACSBG1	526	Q96GR2
EVLAMKMHYISCIFQ	ANKMY2	216	Q8IV38
KVVCYVNMNLMDASV	ELMO3	171	Q96BJ8
MDVQTCTMQLESFGY	GLRA2	181	P23416
CTMQLESFGYTMNDL	GLRA2	186	P23416
IMCLRAIMNYQSGFS	FMNL1	231	O95466
VCKNGFVMQMTSDLI	GK5	441	Q6ZS86
IASMLYSRMNIKCSF	KANK2	821	Q63ZY3
VVCLMVYQKAAMRSA	GPR63	101	Q9BZJ6
YIGTLGKNDTMMCAV	EML5	856	Q05BV3
YAKAAFCLEELMMTN	EMC2	171	Q15006
SAKCFGYMTQQLMNL	HDAC7	816	Q8WUI4
MFGSTYICEQLFSIM	GTF2IRD2	911	Q86UP8
MFGSTYICEQLFSIM	GTF2IRD2B	911	Q6EKJ0
QDSKMGFVINAIYAM	GRM1	406	Q13255
YSCIALKVTANQMEM	DIPK1A	391	Q5T7M9
DGELLLMTDYKQCMA	HSD17B2	176	P37059
LMTDYKQCMAVNFFG	HSD17B2	181	P37059
QSTGMQECRKYFKML	SEC22A	26	Q96IW7
RQVCVQYMKDTNMLF	SLC13A5	76	Q86YT5
GNAVVSYIMKQCVFM	C2CD5	936	Q86YS7
FTCEMLVKMYSLGLQ	CACNA1D	566	Q01668
FSKGYQGLTNCMMAA	PAOX	221	Q6QHF9
KNLMVCNARLMAYTS	RTKN2	56	Q8IZC4
PMSKECTFQTYLTMQ	SYDE2	1141	Q5VT97
KMEQFMESCELITYL	AK9	1861	Q5TCS8
SMEYFQFMKKLLTCN	USP9X	2006	Q93008
GQENKVYACMMVFFL	SELENOT	121	P62341
CIQFGFMMDKTNILN	SMCHD1	1461	A6NHR9
SIMYGCVTLMKVTGQ	SLC9A6	196	Q92581
VCVYSMADIRMVFNG	SEMA3F	371	Q13275
DLKVCMFSNMTNYEV	SH3BP4	536	Q9P0V3
QAVANVSIGAMFCMY	SLC38A5	291	Q8WUX1
AFYQALKGMENMLCI	SAMD9L	566	Q8IVG5
KNCENFYSFMIMKSN	SAMD9L	881	Q8IVG5
SSNFMYLMVEFRCVK	PIK3C3	211	Q8NEB9
MESMLISGYALNCVV	TCP1	206	P17987
LYLLQCNMKFMTQSA	TANC1	736	Q9C0D5
NYESMLKECLVGRMA	CYB5R4	116	Q7L1T6
MSKQVCLALMLGSYL	OR5AR1	136	Q8NGP9
LCYSSAITPKMMVNF	OR8U3	71	Q8NH85
VTCAQQAGLYMKMEP	BRPF1	411	P55201
LQMKYCQAFMQNSLS	CLEC9A	91	Q6UXN8
ENLSNFIKAMVSYGM	CNN2	86	Q99439
EMQFRECSINGMKYQ	ATP11B	416	Q9Y2G3
ITDVIMAFQAMCRGY	MYH11	786	P35749
GMNCILMKQYIEFVA	RRM2B	276	Q7LG56
DVQKYNCMMVRVFGK	VWDE	936	Q8N2E2
YACARNMISTVKMFL	TICRR	661	Q7Z2Z1
QSCLYQFTSMELLMG	USP45	621	Q70EL2
KTCGDLQYMTMAKLQ	REV1	666	Q9UBZ9
ITACAMTMNKYVEEN	SLC9A2	336	Q9UBY0
KLIGMNCTLMKQYIE	RRM2	311	P31350
YYKMQISMLQQSTCG	SRPX2	356	O60687
VQEMDMGFYSCVAKS	ROBO3	511	Q96MS0
QGQFIELCKTMYNMF	TBC1D9	1026	Q6ZT07
QEKTAMDVFVCTYFM	GC	301	P02774
SKVINLLNCDIMMYI	UBR1	876	Q8IWV7
TLKSLLMFTMENCFY	NUP188	1646	Q5SRE5
LMFTMENCFYLLISQ	NUP188	1651	Q5SRE5
CLQFTPVMMAAVKTY	DPF2	306	Q92785
YQKCLVMGMKREAVQ	RXRG	196	P48443
VGMQKTYSMICLAID	RHPN2P1	506	A8MT19
NTVAAGTMTGMLYKC	TIMM23B	156	Q5SRD1
MAYIMLCRKTSQQEH	VSIG4	301	Q9Y279
GNTCYMNSVIQALFM	USP38	451	Q8NB14
CMDKMTAVYANILSD	TSHZ2	121	Q9NRE2
LKQGQMYMADSQCTS	UACA	396	Q9BZF9
QILGLTFAMTMYCQV	TSPAN4	216	O14817
TFAMTMYCQVVKADT	TSPAN4	221	O14817
MSKFTVLFYQMAKCD	ZMYM6	546	O95789
AYCVMGFTQKSNMKL	ZNF236	1781	Q9UL36
CAYLNAASAIGMKMQ	SEPSECS	431	Q9HD40
MISYAGMVFCEAKIN	KDR	191	P35968
VMYIITKNCSMGDFE	WNT8A	96	Q9H1J5
NEVMSQFYAVLMGKR	TSNAXIP1	451	Q2TAA8
ELDCINTASKIYMQM	UBR4	2671	Q5T4S7
YFLGKQDMAIGTCNM	TTC22	306	Q5TAA0
MTVKCSYSRNDMLLN	ZP2	461	Q05996
NTVAAGTMTGMLYKC	TIMM23	156	O14925
VQQYMLTLFAAMLSC	ULK4	706	Q96C45
TCSYMIDNVILLMNG	ATP6V0D2	101	Q8N8Y2
KIEDMGIYSCMAQNT	LRIG2	666	O94898
MYTAGFLQIQEIMEK	NACC1	101	Q96RE7
YCMLMGVSAEDKQLL	MYO7B	256	Q6PIF6
GIRLQCFMKYFTDEM	MYOM2	1246	P54296