Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair via homologous recombination	EPC2 BRD8 EP400 EPC1 TRRAP	1.01e-06	44	85	5	GO:1905168
GeneOntologyBiologicalProcess	regulation of double-strand break repair via homologous recombination	EPC2 SETD2 BRD8 EP400 EPC1 TRRAP	1.20e-06	83	85	6	GO:0010569
GeneOntologyBiologicalProcess	positive regulation of DNA recombination	EPC2 BRD8 EP400 EPC1 TRRAP	1.99e-05	80	85	5	GO:0045911
GeneOntologyBiologicalProcess	positive regulation of DNA repair	UIMC1 EPC2 BRD8 EP400 EPC1 TRRAP	2.79e-05	143	85	6	GO:0045739
GeneOntologyBiologicalProcess	regulation of double-strand break repair	EPC2 SETD2 BRD8 EP400 EPC1 TRRAP	3.13e-05	146	85	6	GO:2000779
GeneOntologyBiologicalProcess	regulation of DNA recombination	EPC2 SETD2 BRD8 EP400 EPC1 TRRAP	3.65e-05	150	85	6	GO:0000018
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair	EPC2 BRD8 EP400 EPC1 TRRAP	4.57e-05	95	85	5	GO:2000781
GeneOntologyBiologicalProcess	regulation of cell cycle	CDCA2 UIMC1 EPC2 TICRR SETD2 BRD8 EP400 SPDYE7P PHACTR4 EPC1 CDKL4 SIN3A TADA2A ECT2 TRRAP RAD23A	4.73e-05	1256	85	16	GO:0051726
GeneOntologyBiologicalProcess	regulation of DNA repair	UIMC1 EPC2 SETD2 BRD8 EP400 EPC1 TRRAP	5.15e-05	234	85	7	GO:0006282
GeneOntologyBiologicalProcess	regulation of DNA metabolic process	UIMC1 EPC2 TICRR SETD2 BRD8 EP400 GZMA EPC1 TRRAP HNRNPA2B1	1.07e-04	564	85	10	GO:0051052
GeneOntologyBiologicalProcess	double-strand break repair via homologous recombination	EPC2 SETD2 BRD8 EP400 EPC1 TRRAP	1.27e-04	188	85	6	GO:0000724
GeneOntologyBiologicalProcess	recombinational repair	EPC2 SETD2 BRD8 EP400 EPC1 TRRAP	1.51e-04	194	85	6	GO:0000725
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	EPC2 BRD8 EP400 ACTBL2 EPC1 TRRAP	3.15e-09	32	85	6	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	EPC2 BRD8 EP400 ACTBL2 EPC1 TRRAP	3.15e-09	32	85	6	GO:0043189
GeneOntologyCellularComponent	protein acetyltransferase complex	EPC2 NAA35 BRD8 EP400 ACTBL2 EPC1 TADA2A TRRAP	1.00e-08	104	85	8	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	EPC2 NAA35 BRD8 EP400 ACTBL2 EPC1 TADA2A TRRAP	1.45e-08	109	85	8	GO:1902493
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	EPC2 BRD8 EP400 ACTBL2 EPC1 TRRAP	2.71e-08	45	85	6	GO:1902562
GeneOntologyCellularComponent	histone acetyltransferase complex	EPC2 BRD8 EP400 ACTBL2 EPC1 TADA2A TRRAP	1.10e-07	94	85	7	GO:0000123
GeneOntologyCellularComponent	Swr1 complex	BRD8 EP400 TRRAP	1.80e-05	13	85	3	GO:0000812
GeneOntologyCellularComponent	intracellular protein-containing complex	EPC2 NAA35 BRD8 EP400 TBPL1 EIF4A1 ACTBL2 EPC1 GATB TADA2A DGCR8 ECT2 TRRAP RAD23A	3.51e-05	972	85	14	GO:0140535
GeneOntologyCellularComponent	piccolo histone acetyltransferase complex	EPC2 EPC1	9.75e-05	4	85	2	GO:0032777
GeneOntologyCellularComponent	INO80-type complex	BRD8 EP400 TRRAP	1.97e-04	28	85	3	GO:0097346
GeneOntologyCellularComponent	nucleosome	EPC2 BRD8 EP400 EPC1 TRRAP	2.50e-04	138	85	5	GO:0000786
GeneOntologyCellularComponent	histone deacetylase complex	BRD8 EP400 SIN3A TRRAP	4.01e-04	85	85	4	GO:0000118
GeneOntologyCellularComponent	transferase complex	EPC2 NAA35 BRD8 EP400 TBPL1 ACTBL2 EPC1 KMT2A DAPK1 TADA2A TRRAP	1.77e-03	963	85	11	GO:1990234
Domain	Enhancer_polycomb	EPC2 EPC1	2.00e-05	2	84	2	IPR024943
Domain	Enhancer_polycomb_C	EPC2 EPC1	2.00e-05	2	84	2	IPR009607
Domain	E_Pc_C	EPC2 EPC1	2.00e-05	2	84	2	PF06752
Domain	MAGE	MAGED4 MAGED2 TRO	4.75e-04	34	84	3	SM01373
Domain	EPL1	EPC2 EPC1	5.50e-04	8	84	2	PF10513
Domain	Enhancer_polycomb-like_N	EPC2 EPC1	5.50e-04	8	84	2	IPR019542
Domain	MAGE	MAGED4 MAGED2 TRO	5.63e-04	36	84	3	PS50838
Domain	MAGE	MAGED4 MAGED2 TRO	5.63e-04	36	84	3	PF01454
Domain	MHD_dom	MAGED4 MAGED2 TRO	5.63e-04	36	84	3	IPR002190
Domain	GDS_CDC24_CS	ARHGEF10 ARHGEF11 ECT2	7.14e-04	39	84	3	IPR001331
Domain	WW	SETD2 MAGI3 DGCR8	1.23e-03	47	84	3	PF00397
Domain	WW	SETD2 MAGI3 DGCR8	1.31e-03	48	84	3	SM00456
Domain	WW_DOMAIN_2	SETD2 MAGI3 DGCR8	1.56e-03	51	84	3	PS50020
Domain	WW_DOMAIN_1	SETD2 MAGI3 DGCR8	1.56e-03	51	84	3	PS01159
Domain	WW_dom	SETD2 MAGI3 DGCR8	1.65e-03	52	84	3	IPR001202
Domain	Post-SET_dom	SETD2 KMT2A	2.30e-03	16	84	2	IPR003616
Domain	PostSET	SETD2 KMT2A	2.30e-03	16	84	2	SM00508
Domain	POST_SET	SETD2 KMT2A	2.30e-03	16	84	2	PS50868
Domain	DH_1	ARHGEF10 ARHGEF11 ECT2	2.87e-03	63	84	3	PS00741
Domain	RhoGEF	ARHGEF10 ARHGEF11 ECT2	3.56e-03	68	84	3	SM00325
Domain	RhoGEF	ARHGEF10 ARHGEF11 ECT2	3.87e-03	70	84	3	PF00621
Domain	DH_2	ARHGEF10 ARHGEF11 ECT2	3.87e-03	70	84	3	PS50010
Domain	DH-domain	ARHGEF10 ARHGEF11 ECT2	4.02e-03	71	84	3	IPR000219
Domain	-	ARHGEF10 ARHGEF11 ECT2	4.02e-03	71	84	3	1.20.900.10
Pubmed	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.	EPC2 BRD8 EP400 EPC1 SIN3A TRRAP	1.87e-11	23	86	6	14966270
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CDCA2 SART1 UIMC1 GPR19 STXBP2 MAGED2 TRO EIF4A1 ACTBL2 HSPH1 UBR4 RPF2 GATB KMT2A MAGI3 ATP10B ZNF318 RPL13A TNNT1 HNRNPA2B1	2.65e-10	1442	86	20	35575683
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	EPC2 BRD8 EP400 EPC1 KMT2A TRRAP	9.35e-10	42	86	6	35705031
Pubmed	Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.	EPC2 BRD8 EP400 EPC1 SIN3A TRRAP	9.35e-10	42	86	6	29028833
Pubmed	MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.	EPC2 BRD8 EP400 EPC1 TRRAP	2.67e-09	23	86	5	20332121
Pubmed	CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.	EPC2 BRD8 EP400 EPC1 TRRAP	2.67e-09	23	86	5	31281901
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CDCA2 SART1 NAA35 PTPN14 EP400 MAGED2 TBPL1 SGPL1 EIF4A1 HSPH1 UBR4 RPF2 SFXN3 RPL13A ECT2 TRRAP PGD HNRNPA2B1	4.62e-09	1353	86	18	29467282
Pubmed	Human transcription factor protein interaction networks.	CDCA2 UIMC1 EPC2 BRD8 CDC42BPA EP400 PITRM1 NOP16 MAGED2 HSPH1 UBR4 EPC1 KMT2A ZNF318 SIN3A TADA2A RPL13A TRRAP	1.07e-08	1429	86	18	35140242
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	EPC2 BRD8 EP400 ACTBL2 EPC1 TRRAP	1.41e-08	65	86	6	22496869
Pubmed	Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells.	EPC2 EPC1 KMT2A	1.46e-08	3	86	3	24166297
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CDCA2 SART1 UIMC1 EPC2 TICRR SETD2 BRD8 EP400 NOP16 EPC1 KMT2A ZNF318 SIN3A TADA2A RPL13A TRRAP HNRNPA2B1	1.59e-08	1294	86	17	30804502
Pubmed	A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.	EPC2 BRD8 EP400 EPC1 TRRAP	2.52e-08	35	86	5	20946988
Pubmed	The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.	EPC2 BRD8 EP400 EPC1 TRRAP	3.87e-08	38	86	5	27153538
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	EPC2 EP400 TBPL1 EPC1 KMT2A SIN3A TRRAP	4.49e-08	134	86	7	25452129
Pubmed	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.	EPC2 BRD8 EPC1 SIN3A TRRAP	6.50e-08	42	86	5	16387653
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SART1 EPC2 NAA35 SETD2 BRD8 PTPN14 EP400 CMC1 SGPL1 EPC1 ZNF318 SIN3A TADA2A TRRAP IQCM	9.28e-08	1116	86	15	31753913
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	PTPN1 NAA35 DYNC2H1 HPRT1 EIF4A1 ACTBL2 HSPH1 UBR4 KMT2A DAPK1 RPL13A PGD HNRNPA2B1	9.41e-08	807	86	13	30575818
Pubmed	Hdac6 regulates Tip60-p400 function in stem cells.	EPC2 BRD8 EP400 EPC1 TRRAP	1.29e-07	48	86	5	24302573
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	UIMC1 SETD2 BRD8 CDC42BPA EP400 NOP16 SGPL1 EIF4A1 ACTBL2 HSPH1 RPF2 KMT2A ZNF318 DGCR8 ARHGEF11 ECT2 TRRAP	1.30e-07	1497	86	17	31527615
Pubmed	The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.	EPC2 BRD8 EPC1 TRRAP	1.31e-07	19	86	4	15647280
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	CDCA2 SART1 EPC2 EP400 EPC1 KMT2A ZNF318 SIN3A TRRAP	1.70e-07	339	86	9	30415952
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SART1 EP400 UBR4 RPF2 PUS1 KMT2A SIN3A TRMT5 TRRAP	1.79e-07	341	86	9	32971831
Pubmed	Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.	BRD8 EP400 EPC1 TRRAP	2.46e-07	22	86	4	12963728
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	SART1 PTPN14 NOP16 MAGED2 SGPL1 EIF4A1 HSPH1 RPF2 DGCR8 RPL13A HNRNPA2B1	3.57e-07	615	86	11	31048545
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CDCA2 SART1 PTPN1 PITRM1 MAGED2 DYNC2H1 HPRT1 EIF4A1 HSPH1 UBR4 RPF2 SFXN3 PUS1 RPL13A PGD HNRNPA2B1	3.74e-07	1425	86	16	30948266
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SART1 UIMC1 SETD2 BRD8 EP400 MAGED2 PHACTR4 KMT2A ZNF318 SIN3A TRRAP HNRNPA2B1	4.60e-07	774	86	12	15302935
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SART1 UIMC1 SETD2 BRD8 EP400 EIF4A1 UBR4 THUMPD1 KMT2A SIN3A TRRAP PGD RAD23A	1.24e-06	1014	86	13	32416067
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SART1 EPC2 BRD8 EP400 HIPK1 TRO UBR4 EPC1 THUMPD1 SIN3A ECT2 TRRAP	1.34e-06	857	86	12	25609649
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	DHX58 STXBP2 PITRM1 HPRT1 HSPH1 UBR4 ARHGEF11 TRRAP	2.29e-06	344	86	8	30333137
Pubmed	The highly conserved and multifunctional NuA4 HAT complex.	BRD8 EP400 EPC1	2.37e-06	11	86	3	15196461
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	CDCA2 SART1 TICRR MAGED2 EIF4A1 SIN3A DGCR8 RPL13A ECT2 TRRAP HNRNPA2B1	2.75e-06	759	86	11	35915203
Pubmed	MRG15 is a novel PALB2-interacting factor involved in homologous recombination.	BRD8 EP400 TRRAP	3.16e-06	12	86	3	19553677
Pubmed	ANP32E is a histone chaperone that removes H2A.Z from chromatin.	BRD8 EP400 TRRAP	3.16e-06	12	86	3	24463511
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PTPN1 NAA35 PTPN14 CDC42BPA ARHGEF10 DYNC2H1 HSPH1 UBR4 PHACTR4 RPF2 GATB RPL13A PGD HNRNPA2B1 RAD23A	3.40e-06	1487	86	15	33957083
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CDCA2 SART1 PTPN1 CDC42BPA EP400 MAGED2 PHACTR4 ZNF318 DGCR8 HNRNPA2B1 SYDE1	3.44e-06	777	86	11	35844135
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CDCA2 SART1 UIMC1 SETD2 BRD8 EP400 NOP16 EIF4A1 KMT2A ZNF318 DGCR8 HNRNPA2B1	4.02e-06	954	86	12	36373674
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	EP400 KMT2A TRRAP	4.10e-06	13	86	3	16510874
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	EPC2 NAA35 SETD2 BRD8 PITRM1 SGPL1 EIF4A1 HSPH1 UBR4 EPC1 KMT2A TADA2A TRRAP HNRNPA2B1	4.51e-06	1327	86	14	32694731
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	SART1 BRD8 EP400 EIF4A1 ACTBL2 PHACTR4 ZNF318 TADA2A TRRAP	4.64e-06	506	86	9	30890647
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CDCA2 SART1 BRD8 EP400 EPC1 KMT2A SIN3A	4.77e-06	268	86	7	33640491
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	CDCA2 SART1 PTPN1 NOP16 EIF4A1 HSPH1 RPF2 SIN3A DGCR8 RPL13A ECT2 HNRNPA2B1	5.79e-06	989	86	12	36424410
Pubmed	Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells.	SGPP1 SGPL1	6.04e-06	2	86	2	29375197
Pubmed	SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia.	SETD2 KMT2A	6.04e-06	2	86	2	29249820
Pubmed	The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals.	EPC2 EPC1	6.04e-06	2	86	2	9735366
Pubmed	MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.	SETD2 KMT2A	6.04e-06	2	86	2	29777171
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SART1 EP400 MAGED2 HSPH1 KMT2A SIN3A TRRAP HNRNPA2B1	6.21e-06	394	86	8	27248496
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEM ACTBL2 POTEG	6.50e-06	15	86	3	16824795
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	EP400 KMT2A TRRAP	6.50e-06	15	86	3	16510875
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	SART1 PTPN14 NOP16 TRO EIF4A1 ACTBL2 HSPH1 RPF2 RPL13A HNRNPA2B1	6.94e-06	678	86	10	30209976
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD2 BRD8 PTPN14 EP400 PHACTR4 KMT2A ZNF318 SIN3A TRRAP	8.92e-06	549	86	9	38280479
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SART1 HPRT1 EIF4A1 HSPH1 UBR4 PUS1 RPL13A PGD HNRNPA2B1	9.18e-06	551	86	9	34728620
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	SART1 NAA35 BRD8 CDC42BPA EP400 UBR4 TRRAP	9.94e-06	300	86	7	28561026
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SART1 PTPN1 PTPN14 NOP16 MAGED2 SGPL1 EIF4A1 ACTBL2 HSPH1 RPF2 RPL13A ECT2 HNRNPA2B1	1.27e-05	1257	86	13	36526897
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SART1 EPC2 EP400 HPRT1 EIF4A1 HSPH1 KMT2A ZNF318 SIN3A TRRAP HNRNPA2B1 RAD23A	1.72e-05	1103	86	12	34189442
Pubmed	Identification of functional cooperative mutations of SETD2 in human acute leukemia.	SETD2 KMT2A	1.81e-05	3	86	2	24509477
Pubmed	Comparative expression analysis of the MAGED genes during embryogenesis and brain development.	MAGED2 TRO	1.81e-05	3	86	2	15162511
Pubmed	Ubiquitin Chains Bearing Genetically Encoded Photo-Cross-Linkers Enable Efficient Covalent Capture of (Poly)ubiquitin-Binding Domains.	UIMC1 RAD23A	1.81e-05	3	86	2	30668904
Pubmed	The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases.	HPRT1 PECAM1	1.81e-05	3	86	2	19151728
Pubmed	HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events.	DGCR8 HNRNPA2B1	1.81e-05	3	86	2	26321680
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	SART1 NOP16 ARHGEF10 SGPL1 EIF4A1 UBR4 KMT2A RPL13A HNRNPA2B1	1.83e-05	601	86	9	33658012
Pubmed	H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization.	EP400 EPC1 TRRAP	1.88e-05	21	86	3	22467210
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SART1 UIMC1 EP400 EIF4A1 UBR4 SIN3A HNRNPA2B1	1.91e-05	332	86	7	32786267
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	EP400 EPC1 KMT2A TRRAP	2.66e-05	69	86	4	28481362
Pubmed	A protein interaction landscape of breast cancer.	UIMC1 PTPN14 SGPL1 HPRT1 RIN2 HSPH1 UBR4 RPL13A RAD23A	2.77e-05	634	86	9	34591612
Pubmed	P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.	EP400 HSPH1 TRRAP	3.23e-05	25	86	3	36708875
Pubmed	The p400/Brd8 chromatin remodeling complex promotes adipogenesis by incorporating histone variant H2A.Z at PPARγ target genes.	BRD8 EP400	3.61e-05	4	86	2	23064015
Pubmed	MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.	HPRT1 KMT2A	3.61e-05	4	86	2	31852898
Pubmed	Definitive hematopoiesis requires the mixed-lineage leukemia gene.	PECAM1 KMT2A	3.61e-05	4	86	2	15030765
Pubmed	Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126.	HPRT1 PECAM1	3.61e-05	4	86	2	18987025
Pubmed	A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.	HPRT1 PECAM1	3.61e-05	4	86	2	18519813
Pubmed	Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains.	UIMC1 RAD23A	3.61e-05	4	86	2	23823328
Pubmed	Importance of suitable reference gene selection for quantitative real-time PCR: special reference to mouse myocardial infarction studies.	HPRT1 RPL13A	3.61e-05	4	86	2	21858224
Pubmed	Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model.	HPRT1 DGCR8	3.61e-05	4	86	2	18469815
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SART1 STXBP2 EP400 HPRT1 EIF4A1 ACTBL2 RPF2 ZNF318 RPL13A TRRAP HNRNPA2B1	4.46e-05	1024	86	11	24711643
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SART1 CDC42BPA NOP16 SGPL1 EIF4A1 RPF2 KMT2A RPL13A TRRAP HNRNPA2B1	4.64e-05	847	86	10	35850772
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDCA2 PTPN14 CDC42BPA SASH1 ARHGEF10 PHACTR4 KMT2A MAGI3 ECT2 SYDE1	5.32e-05	861	86	10	36931259
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	SART1 CDC42BPA PITRM1 EIF4A1 HSPH1 RPL13A ECT2 HNRNPA2B1	5.74e-05	538	86	8	28524877
Pubmed	DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression.	DAPK1 RPL13A	6.01e-05	5	86	2	18995835
Pubmed	Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium.	HPRT1 PECAM1	6.01e-05	5	86	2	11015584
Pubmed	N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.	NAA35 UBR4	6.01e-05	5	86	2	37891180
Pubmed	A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans.	BRD8 EPC1	6.01e-05	5	86	2	36066422
Pubmed	A chemokine targets the nucleus: Cxcl12-gamma isoform localizes to the nucleolus in adult mouse heart.	PECAM1 TNNT1	6.01e-05	5	86	2	19859557
Pubmed	Gestational intermittent hyperoxia rescues murine genetic congenital heart disease in part.	PECAM1 TNNT1	6.01e-05	5	86	2	33758249
Pubmed	Mixed-linkage ubiquitin chains send mixed messages.	UIMC1 RAD23A	6.01e-05	5	86	2	23562397
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	CDCA2 EPC2 EP400 MAGED2 DYNC2H1 EPC1 RPL13A	6.03e-05	398	86	7	35016035
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PTPN1 STXBP2 TBPL1 HPRT1 EIF4A1 UBR4 THUMPD1 SIN3A TRRAP	6.22e-05	704	86	9	29955894
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	SART1 MAGED2 HPRT1 EIF4A1 HSPH1 RPF2 RPL13A PGD HNRNPA2B1	6.93e-05	714	86	9	28302793
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	CDC42BPA EP400 EIF4A1 KMT2A SIN3A TADA2A HNRNPA2B1	7.37e-05	411	86	7	35182466
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	PTPN1 HPRT1 EIF4A1 SCN7A DGCR8 PGD HNRNPA2B1 RAD23A	7.40e-05	558	86	8	35063084
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PTPN1 PTPN14 PITRM1 MAGED2 ACTBL2 UBR4 RPF2 GATB PUS1 THUMPD1 RPL13A TRMT5 HNRNPA2B1	7.65e-05	1496	86	13	32877691
Pubmed	Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development.	HPRT1 PECAM1	9.01e-05	6	86	2	37770184
Pubmed	The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors.	PITRM1 HPRT1	9.01e-05	6	86	2	19877269
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEM POTEG	9.01e-05	6	86	2	17171436
Pubmed	Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.	EP400 TRRAP	9.01e-05	6	86	2	20070254
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	STXBP2 EP400 TBPL1 HPRT1 EIF4A1 HSPH1 UBR4 RPF2 PUS1 KMT2A RPL13A HNRNPA2B1	9.58e-05	1318	86	12	30463901
Pubmed	RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.	EPC2 BRD8 EPC1	9.83e-05	36	86	3	17573780
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	EPC2 RIN2 EPC1 KMT2A HNRNPA2B1	1.02e-04	186	86	5	33637726
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SETD2 DYNC2H1 EIF4A1 ACTBL2 TRRAP	1.04e-04	187	86	5	26460568
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	UIMC1 SETD2 PTPN14 EP400 DYNC2H1 HIPK1 HPRT1 ZNF318	1.06e-04	588	86	8	38580884
Pubmed	Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.	PECAM1 MAGI3	1.26e-04	7	86	2	24025447
Interaction	PLAC1 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	4.73e-08	24	85	5	int:PLAC1
Interaction	JAZF1 interactions	EPC2 BRD8 EP400 MAGED2 EPC1 TRRAP	2.17e-07	61	85	6	int:JAZF1
Interaction	EPC2 interactions	EPC2 BRD8 EP400 EPC1 TRRAP HNRNPA2B1	3.82e-07	67	85	6	int:EPC2
Interaction	MRGBP interactions	EPC2 BRD8 EP400 EPC1 KMT2A DAPK1 TRRAP	3.89e-07	109	85	7	int:MRGBP
Interaction	FOXR2 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	8.92e-07	42	85	5	int:FOXR2
Interaction	FOXR1 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	1.13e-06	44	85	5	int:FOXR1
Interaction	MYCL interactions	EPC2 BRD8 EP400 EPC1 TRRAP	1.76e-06	48	85	5	int:MYCL
Interaction	BRD8 interactions	EPC2 BRD8 EP400 CMC1 SGPL1 EPC1 TRRAP	3.20e-06	149	85	7	int:BRD8
Interaction	MORF4L1 interactions	EPC2 BRD8 EP400 SGPL1 EPC1 SIN3A TNNT1 TRRAP	4.29e-06	221	85	8	int:MORF4L1
Interaction	MBTD1 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	4.96e-06	59	85	5	int:MBTD1
Interaction	H2BC6 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	6.35e-06	62	85	5	int:H2BC6
Interaction	ELF4 interactions	EPC2 BRD8 EP400 EPC1 TADA2A TRRAP	9.18e-06	115	85	6	int:ELF4
Interaction	KLF8 interactions	CDCA2 EPC2 BRD8 EP400 PITRM1 NOP16 HSPH1 EPC1 DGCR8	1.02e-05	329	85	9	int:KLF8
Interaction	NCBP1 interactions	PTPN1 HSPH1 PUS1 TADA2A RPL13A ECT2 TRRAP PGD HNRNPA2B1	1.79e-05	353	85	9	int:NCBP1
Interaction	KLF12 interactions	EP400 NOP16 EPC1 KMT2A TADA2A RPL13A TRRAP	1.80e-05	194	85	7	int:KLF12
Interaction	TERF2IP interactions	CDCA2 SART1 UIMC1 SETD2 BRD8 EP400 KMT2A ZNF318 DGCR8 TRMT5 ECT2	2.01e-05	552	85	11	int:TERF2IP
Interaction	MEN1 interactions	SART1 CDC42BPA EP400 NOP16 SGPL1 EIF4A1 UBR4 RPF2 PUS1 KMT2A SIN3A RPL13A TRMT5 TRRAP RAD23A	2.36e-05	1029	85	15	int:MEN1
Interaction	EPC1 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	2.36e-05	81	85	5	int:EPC1
Interaction	CIT interactions	SART1 EP400 NOP16 MAGED2 POTEM DYNC2H1 HIPK1 EIF4A1 UBR4 RPF2 SFXN3 KMT2A MAGI3 SIN3A RPL13A ECT2 TRRAP HNRNPA2B1	2.81e-05	1450	85	18	int:CIT
Interaction	SRSF5 interactions	SART1 NOP16 RPF2 SFXN3 KMT2A MAGI3 TADA2A RPL13A ECT2 HNRNPA2B1	3.05e-05	474	85	10	int:SRSF5
Interaction	ING3 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	3.93e-05	90	85	5	int:ING3
Interaction	KLF6 interactions	EPC2 BRD8 EP400 NOP16 EPC1	5.10e-05	95	85	5	int:KLF6
Interaction	HECTD1 interactions	CDCA2 SART1 TICRR PTPN14 MAGED2 ARHGEF10 EIF4A1 HSPH1 SIN3A DGCR8 RPL13A ECT2 TRRAP HNRNPA2B1	5.94e-05	984	85	14	int:HECTD1
Interaction	WWTR1 interactions	SETD2 PTPN14 EP400 PHACTR4 KMT2A DAPK1 ZNF318 SIN3A TRRAP	7.18e-05	422	85	9	int:WWTR1
Interaction	FBL interactions	PTPN1 BRD8 NOP16 MAGED2 TRO ZNF318 RPL13A ECT2 TRRAP PGD RAD23A	7.58e-05	639	85	11	int:FBL
Interaction	MORF4L2 interactions	EPC2 BRD8 EP400 EPC1 SIN3A TRRAP	7.79e-05	168	85	6	int:MORF4L2
Interaction	MEAF6 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	7.85e-05	104	85	5	int:MEAF6
Interaction	EED interactions	SART1 EPC2 PTPN14 STXBP2 EP400 SGPL1 EIF4A1 ACTBL2 HSPH1 UBR4 EPC1 RPF2 DAPK1 SIN3A RPL13A TRRAP HNRNPA2B1	9.51e-05	1445	85	17	int:EED
Interaction	H2BC1 interactions	EPC2 BRD8 EP400 EPC1 ECT2 TRRAP	1.07e-04	178	85	6	int:H2BC1
Interaction	PAPSS2 interactions	STXBP2 DAPK1 ECT2 HNRNPA2B1	1.20e-04	60	85	4	int:PAPSS2
Interaction	YEATS4 interactions	EPC2 BRD8 EP400 ACTBL2 EPC1 TRRAP	1.21e-04	182	85	6	int:YEATS4
Interaction	ING5 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	1.21e-04	114	85	5	int:ING5
Interaction	BIRC3 interactions	CDCA2 SART1 PTPN1 PITRM1 MAGED2 DYNC2H1 HPRT1 EIF4A1 HSPH1 UBR4 RPF2 SFXN3 PUS1 RPL13A PGD HNRNPA2B1	1.26e-04	1334	85	16	int:BIRC3
Interaction	NCL interactions	SART1 SETD2 MAGED2 UBR4 GZMA RPF2 KMT2A ABCC12 DGCR8 RPL13A ECT2 HNRNPA2B1	1.26e-04	798	85	12	int:NCL
Interaction	H2BC10 interactions	EPC2 EP400 EPC1 TRRAP	1.28e-04	61	85	4	int:H2BC10
Interaction	EPS8L2 interactions	STXBP2 SASH1 STX17 HNRNPA2B1	1.28e-04	61	85	4	int:EPS8L2
Interaction	PTEN interactions	PTPN14 CDC42BPA PITRM1 MAGED2 HPRT1 HSPH1 RPF2 SFXN3 KMT2A MAGI3 ZNF318 SIN3A RPL13A	1.33e-04	929	85	13	int:PTEN
Interaction	PML interactions	SART1 UIMC1 BRD8 EP400 MAGED2 HIPK1 RPF2 SFXN3 KMT2A ZNF318 SIN3A RPL13A ECT2	1.38e-04	933	85	13	int:PML
Interaction	AGR2 interactions	PTPN1 NAA35 DYNC2H1 HPRT1 EIF4A1 ACTBL2 HSPH1 UBR4 KMT2A DAPK1 RPL13A PGD HNRNPA2B1	1.40e-04	934	85	13	int:AGR2
Interaction	CSGALNACT1 interactions	BRD8 EP400 EPC1 TRRAP	1.54e-04	64	85	4	int:CSGALNACT1
Interaction	FBXW7 interactions	SART1 EP400 NOP16 MAGED2 ARHGEF10 SGPL1 EIF4A1 UBR4 RPF2 GATB KMT2A SIN3A TADA2A RPL13A HNRNPA2B1	1.55e-04	1215	85	15	int:FBXW7
Interaction	ACTC1 interactions	SART1 BRD8 EP400 EIF4A1 ACTBL2 PHACTR4 DAPK1 ZNF318 TADA2A ECT2 TRRAP	1.57e-04	694	85	11	int:ACTC1
Interaction	YAP1 interactions	SETD2 BRD8 PTPN14 EIF4A1 ACTBL2 HSPH1 THUMPD1 KMT2A ZNF318 SIN3A DGCR8 RPL13A TRRAP HNRNPA2B1	1.84e-04	1095	85	14	int:YAP1
Interaction	ELF1 interactions	EP400 EPC1 KMT2A TADA2A TRRAP	1.94e-04	126	85	5	int:ELF1
Interaction	WWP2 interactions	SART1 PTPN14 NOP16 MAGED2 SGPL1 EIF4A1 HSPH1 RPF2 DGCR8 RPL13A HNRNPA2B1 RAD23A	2.04e-04	840	85	12	int:WWP2
Interaction	SLC1A6 interactions	ARHGEF11 TRRAP	2.61e-04	6	85	2	int:SLC1A6
Interaction	SOX2 interactions	SETD2 BRD8 CDC42BPA EP400 NOP16 MAGED2 HPRT1 EIF4A1 ACTBL2 UBR4 KMT2A SIN3A DGCR8 RPL13A PGD HNRNPA2B1	2.63e-04	1422	85	16	int:SOX2
Interaction	GPBAR1 interactions	SGPL1 SFXN3 STX17	2.99e-04	31	85	3	int:GPBAR1
Interaction	KDM5C interactions	EPC2 BRD8 EP400 EPC1 TRRAP	3.06e-04	139	85	5	int:KDM5C
Interaction	MAP3K19 interactions	TRRAP MAP3K19	3.64e-04	7	85	2	int:MAP3K19
Interaction	VPS72 interactions	EPC2 BRD8 EP400 EPC1 TRRAP	3.84e-04	146	85	5	int:VPS72
Interaction	H3C1 interactions	CDCA2 UIMC1 SETD2 DYNC2H1 ACTBL2 UBR4 PUS1 KMT2A SIN3A RPL13A TRRAP HNRNPA2B1	3.86e-04	901	85	12	int:H3C1
Interaction	CDC42 interactions	SGPP1 PTPN1 PTPN14 CDC42BPA ARHGEF10 DYNC2H1 PHACTR4 SFXN3 PUS1 ARHGEF11 ECT2 TRRAP PGD SYDE1 MAP3K19	3.87e-04	1323	85	15	int:CDC42
Interaction	MKI67 interactions	EPC2 TICRR STXBP2 EP400 RPF2 KMT2A RPL13A ECT2 TRRAP HNRNPA2B1	3.94e-04	648	85	10	int:MKI67
Interaction	KLF3 interactions	EPC2 EP400 PITRM1 EPC1 KMT2A TADA2A	4.08e-04	228	85	6	int:KLF3
Interaction	SRA1 interactions	PUS1 RPL13A BLZF1 HNRNPA2B1	4.20e-04	83	85	4	int:SRA1
Interaction	BOD1L1 interactions	UBR4 KMT2A SIN3A RPL13A ECT2	4.21e-04	149	85	5	int:BOD1L1
Interaction	TRRAP interactions	SART1 EPC2 SETD2 BRD8 EP400 DYNC2H1 EPC1 TADA2A ECT2 TRRAP MAP3K19	4.75e-04	790	85	11	int:TRRAP
Interaction	GNAL interactions	MAGED2 ECT2 TRRAP	5.07e-04	37	85	3	int:GNAL
Interaction	ELF2 interactions	BRD8 EP400 EPC1 KMT2A TRRAP	5.19e-04	156	85	5	int:ELF2
Interaction	NHLH1 interactions	CDCA2 EP400 NOP16 KMT2A	5.25e-04	88	85	4	int:NHLH1
Interaction	CDKN2A interactions	RIN2 ACTBL2 CARF DGCR8 ECT2 TRRAP HNRNPA2B1	5.36e-04	335	85	7	int:CDKN2A
Interaction	ACLY interactions	STXBP2 PITRM1 MAGED2 EIF4A1 UBR4 ECT2 HNRNPA2B1	5.36e-04	335	85	7	int:ACLY
Cytoband	9q21.33	NAA35 DAPK1	5.33e-04	18	87	2	9q21.33
Cytoband	5q35.2	UIMC1 NOP16	1.70e-03	32	87	2	5q35.2
GeneFamily	MAGE family	MAGED4 MAGED2 TRO	2.18e-04	40	53	3	1136
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEM POTEG	6.44e-04	13	53	2	685
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF10 ARHGEF11 ECT2	9.55e-04	66	53	3	722
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN1 PTPN14	1.25e-03	18	53	2	812
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD2 KMT2A	4.45e-03	34	53	2	487
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CDCA2 TICRR EIF4A1 RPF2 ECT2 HNRNPA2B1	1.36e-06	180	86	6	44988c34861df359a68376500c42a64fbcc4b431
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR RNASE9 HSPH1 RPL13A ECT2	2.15e-05	173	86	5	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR RNASE9 HSPH1 RPL13A ECT2	2.15e-05	173	86	5	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN14 SASH1 DAPK1 ATP10B SLC35F5	2.67e-05	181	86	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	SULT1B1 STXBP2 TNNT1 ECT2 PGD	3.12e-05	187	86	5	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDC42BPA SASH1 ARHGEF10 RIN2 PECAM1	3.28e-05	189	86	5	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	URO\|World / Disease, Lineage and Cell Type	SULT1B1 STXBP2 RIN2 TNNT1 PGD	3.62e-05	193	86	5	421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDCA2 TICRR GPR19 CMC1 GZMA	3.71e-05	194	86	5	6cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCell	nucseq-Endothelial-Endothelial_Vascular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDC42BPA SASH1 ARHGEF10 RIN2 PECAM1	3.90e-05	196	86	5	686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCell	(000)_CD14+_Monocyte\|World / immune cells in Peripheral Blood (logTPM normalization)	STXBP2 RIN2 PECAM1 TADA2A PGD	4.00e-05	197	86	5	cff498bc7b153f28dd013eaeb73ead4fb62fb44c
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CDCA2 GPR19 CMC1 TTLL11 GZMA	4.00e-05	197	86	5	52246d1354c4e2b13d48c878643edf843d2b50d2
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDCA2 BRD8 PECAM1 SCN7A ECT2	4.00e-05	197	86	5	1c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell	Caecum-(1)_T_cell-(18)_cycling_gd_T\|Caecum / shred on region, Cell_type, and subtype	CDCA2 GZMA ATP10B TRMT5 ECT2	4.09e-05	198	86	5	64278d8831c81874937e76b561c53928dfc437c5
ToppCell	Caecum-T_cell-cycling_gd_T\|Caecum / Region, Cell class and subclass	CDCA2 GZMA ATP10B TRMT5 ECT2	4.09e-05	198	86	5	5b719b67f8384863077070e1eb7e04a320e6dab4
ToppCell	Sepsis-URO\|Sepsis / Disease, condition lineage and cell class	SULT1B1 STXBP2 RIN2 TNNT1 PGD	4.19e-05	199	86	5	8e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	PTPN1 SETD2 EPC1 KMT2A HNRNPA2B1	4.29e-05	200	86	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
Drug	Spiramycin [8025-81-8]; Up 200; 4.8uM; HL60; HT_HG-U133A	SGPP1 SETD2 CDC42BPA MAGED2 DYNC2H1 KMT2A ATP10B SLC35F5	7.59e-07	200	84	8	2558_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	BRD8 CDC42BPA RIN2 CARF SFXN3 PCMTD2 TADA2A	5.01e-06	182	84	7	1661_UP
Disease	myocardial infarction	STXBP2 SASH1 DYNC2H1 PECAM1 CARF MAGI3	4.98e-04	350	84	6	EFO_0000612
Disease	mean reticulocyte volume	PTPN1 EP400 MAGED2 SGPL1 TRO PUS1 ZNF318 TRRAP	1.99e-03	799	84	8	EFO_0010701
Disease	migraine disorder, pulse pressure measurement	STXBP2 DYNC2H1	2.49e-03	26	84	2	EFO_0005763, MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
VIPEVLSEMKKKTIL	ERICH6B	626	Q5W0A0
SKKKIPRKLMEEIST	EP400	1431	Q96L91
TILEMIKRREKSKRE	EPC1	246	Q9H2F5
TILEMIKRREKTKRE	EPC2	246	Q52LR7
FIRRLLVKDPKKRMT	DAPK1	251	P53355
LSEMEPKVLSERKLK	ARHGEF10	451	O15013
DVLIPKIMREKAKER	CMC1	16	Q7Z7K0
KDVVKRPMDLTSLKR	BRD8	1141	Q9H0E9
KEIITLAPSTMKIKI	ACTBL2	316	Q562R1
DPVVKKIALREIRML	CDKL4	41	Q5MAI5
TREEPTKQIMLVKKE	GZMA	86	P12544
IVPRTKVKTIKMFLI	GPR19	266	Q15760
MKKLREEGPIIKEIS	ARHGEF11	796	O15085
MVSKLKKPRRIILLV	PGD	61	P52209
RADPVMIKEILEKKL	GATB	541	O75879
RLAEEREETRKKPKM	DGCR8	741	Q8WYQ5
REETRKKPKMSIVAS	DGCR8	746	Q8WYQ5
VPDINMEKKLRKIRA	ATP10B	806	O94823
TPLQKSMIVKLVRDK	ATP10B	1031	O94823
KIRMEPDETVKVLKE	RAD23A	16	P54725
IKALKTIKIMEVPVI	ECT2	66	Q9H8V3
TIKIMEVPVIKIKES	ECT2	71	Q9H8V3
VKLDKIMTIIEPVSK	IQCM	131	A0A1B0GVH7
PSSVDIKKVLLEMRK	PTPN1	241	P18031
TKIPIKRSDMLKDII	MAGED2	296	Q9UNF1
KIPIKRADMLKDVIR	MAGED4	431	Q96JG8
TRSPEKKIKRMVEKS	MAGI3	1351	Q5TCQ9
EKAMEVKAVRILVPK	BLZF1	71	Q9H2G9
KKMLTIDADKRITPL	HIPK1	496	Q86Z02
KLEELMKIGTPVKVR	HSPH1	691	Q92598
RVPTDPKIDKKIIRM	CARF	331	Q8N187
LEVTKKFMRDPIRIL	EIF4A1	221	P60842
KFMRDPIRILVKKEE	EIF4A1	226	P60842
ILVMPLEEKLTKITR	PCMTD2	186	Q9NV79
PILYSVKMKEIRKRI	OR51S1	296	Q8NGJ8
KMLSEVLRVKVIAPV	PECAM1	486	P16284
RKKKLRPAEIMTINL	OPN5	61	Q6U736
ERKISMRKPREELVK	PHACTR4	66	Q8IZ21
KMVKVASLLVKRTPR	HPRT1	156	P00492
ELVKRPTISKELMLE	DYNC2H1	426	Q8NCM8
KSVKLPVLKVRSMLL	DHX58	626	Q96C10
VLRSVLKKPSVKMCL	CDCA2	326	Q69YH5
RKRTVKVTLTPLKME	KMT2A	2516	Q03164
KMKKRVVSIVEADPL	GPR22	381	Q99680
EMLPKSFIKLLRSKV	SCUBE3	971	Q8IX30
ETLMLFRISKLRKPK	CFAP47	2221	Q6ZTR5
IETVELRKKKLTMRP	MAP3K19	126	Q56UN5
LSIKMKKLPELRRRL	SYDE1	166	Q6ZW31
IPVLKVRKEIVSKLM	TRMT5	96	Q32P41
MKVRILSERKKPLDI	TNNT1	181	P13805
IMDTLEKKDFLKRRP	SFXN3	246	Q9BWM7
MIKRKVDREDKLDIP	SLC35F5	346	Q8WV83
LKKTREEERLKRTML	TADA2A	306	O75478
QRMRKRKEELSKLLP	LRRC27	371	Q9C0I9
ERREKPPKRKIVLLM	PUS1	76	Q9Y606
LSPMTVKKDIELLKR	ODAD2	196	Q5T2S8
RIAEMTDIKPILRKL	PITRM1	751	Q5JRX3
VPMDERFRTLKKKLE	PTPN14	891	Q15678
VLIIRDVMKKITIPL	SGPP1	376	Q9BX95
AVPIVLKRLKMKEEE	SIN3A	691	Q96ST3
TKEKVKRRVLIEPGM	RNASE9	61	P60153
VSLRRMKKILIDKSP	ABCC12	406	Q96J65
IMILKDKLEKTRRES	CDC42BPA	736	Q5VT25
VPLRKRKVKAMEVDI	NOP16	66	Q9Y3C1
MLSPKDILRKDLKLV	SULT1B1	1	O43704
MDTLDRVVKPKTKRA	RPF2	1	Q9H7B2
KLTRKMPIIGRKIQD	SGPL1	76	O95470
HEIKMLRRKKPITLE	CILP	566	O75339
SPEKKVMLLLRVCKL	RIN2	666	Q8WYP3
KVLMKLRKPRITATI	TBPL1	46	P62380
VIRDTLRLMDPLKKK	TTLL11	566	Q8NHH1
KQVMEKLLPKRVREV	TICRR	186	Q7Z2Z1
KLLPKRVREVMVARK	TICRR	191	Q7Z2Z1
KKKVRPLSREITMSQ	NAA35	566	Q5VZE5
MEKTLETVPLERKKR	HNRNPA2B1	1	P22626
KRMVVPAALKVVRLK	RPL13A	116	P40429
TKIPIKRSDMLRDVI	TRO	461	Q12816
KMKLKRRRVSLVLPE	SPDYE7P	36	Q495Y7
KDDLVLLKRMIDPVK	STX17	81	P56962
KIKDSMKLIVPVLLD	STXBP2	381	Q15833
VRKKLIRVEEMKKPS	SASH1	271	O94885
LTPEEMVTFKKTKRR	SART1	391	O43290
DTPKKLMFRRLKIIS	SETD2	1871	Q9BYW2
MKDPRVLKCKLRVTN	ZNF516-DT	146	Q6ZTR6
IGKTREELKPLISMK	SCN7A	1016	Q01118
SVISIMKPVRKRKTA	UBR4	2261	Q5T4S7
KVPRKDLIVMLKDTD	POTEG	151	Q6S5H5
KVPRKDLIVMLKDTD	POTEM	151	A6NI47
LVKPLLEVVMKTERA	TRRAP	1531	Q9Y4A5
EEVSVMPKKSILKKR	ZNF318	371	Q5VUA4
MPRRKKKVKEVSESR	UIMC1	1	Q96RL1
TKKKKTRVILRMLPI	THUMPD1	151	Q9NXG2