Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	arachidonate 12(S)-lipoxygenase activity	ALOX12 ALOX5 ALOX15	3.30e-07	4	88	3	GO:0004052
GeneOntologyMolecularFunction	hepoxilin-epoxide hydrolase activity	ALOX12 ALOX15	1.92e-05	2	88	2	GO:0047977
GeneOntologyMolecularFunction	calcium-dependent cysteine-type endopeptidase activity	CAPN8 CAPN2 CAPN3	5.38e-05	17	88	3	GO:0004198
GeneOntologyMolecularFunction	linoleate 13S-lipoxygenase activity	ALOX12 ALOX15	5.74e-05	3	88	2	GO:0016165
GeneOntologyMolecularFunction	arylamine N-acetyltransferase activity	NAT1 NAT2	5.74e-05	3	88	2	GO:0004060
GeneOntologyMolecularFunction	arachidonate 15-lipoxygenase activity	ALOX12 ALOX15	5.74e-05	3	88	2	GO:0050473
GeneOntologyMolecularFunction	ceramide floppase activity	ABCB1 ABCB4	5.74e-05	3	88	2	GO:0099038
GeneOntologyMolecularFunction	dioxygenase activity	ALKBH3 PLOD1 ALOX12 ALOX5 ALOX15	7.29e-05	98	88	5	GO:0051213
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCB1 ABCB4	1.15e-04	4	88	2	GO:0046623
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ALOX12 ALOX5 ALOX15	1.77e-04	25	88	3	GO:0016702
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	ALOX12 ALOX5 ALOX15	2.00e-04	26	88	3	GO:0016701
GeneOntologyMolecularFunction	carbohydrate binding	CRYBG2 IGF2R ALKBH3 PLOD1 G6PD CNTN1 SORD	4.40e-04	310	88	7	GO:0030246
GeneOntologyMolecularFunction	insulin-like growth factor II binding	IGF2R INSR	5.28e-04	8	88	2	GO:0031995
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCB1 ABCB4	5.28e-04	8	88	2	GO:0090554
GeneOntologyMolecularFunction	vitamin binding	ALKBH3 OGDHL PLOD1 PCCA SEC14L2	7.32e-04	161	88	5	GO:0019842
GeneOntologyMolecularFunction	monosaccharide binding	IGF2R ALKBH3 PLOD1 G6PD	8.26e-04	95	88	4	GO:0048029
GeneOntologyMolecularFunction	iron ion binding	ALKBH3 PLOD1 ALOX12 ALOX5 ALOX15	8.40e-04	166	88	5	GO:0005506
GeneOntologyMolecularFunction	epoxide hydrolase activity	ALOX12 ALOX15	1.03e-03	11	88	2	GO:0004301
GeneOntologyMolecularFunction	hydrolase activity, acting on ether bonds	ALOX12 ALOX15	1.45e-03	13	88	2	GO:0016801
GeneOntologyMolecularFunction	ether hydrolase activity	ALOX12 ALOX15	1.45e-03	13	88	2	GO:0016803
GeneOntologyMolecularFunction	oxidoreductase activity	PYROXD1 ALKBH3 OGDHL GSTO2 PLOD1 G6PD ALOX12 ALOX5 ALOX15 SORD	1.97e-03	766	88	10	GO:0016491
GeneOntologyMolecularFunction	floppase activity	ABCB1 ABCB4	2.21e-03	16	88	2	GO:0140328
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRU PTPRT	2.50e-03	17	88	2	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRU PTPRT	2.50e-03	17	88	2	GO:0019198
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGF2R INSR	3.13e-03	19	88	2	GO:0005520
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCB1 ABCB4	3.46e-03	20	88	2	GO:0008525
GeneOntologyMolecularFunction	L-ascorbic acid binding	ALKBH3 PLOD1	3.46e-03	20	88	2	GO:0031418
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCB1 ABCB4	3.46e-03	20	88	2	GO:0046624
GeneOntologyMolecularFunction	carboxylic acid binding	IGF2R INSR ALKBH3 PLOD1 PCCA	4.12e-03	239	88	5	GO:0031406
GeneOntologyBiologicalProcess	lipoxin biosynthetic process	ALOX12 ALOX5 ALOX15	3.10e-07	4	89	3	GO:2001301
GeneOntologyBiologicalProcess	lipoxin metabolic process	ALOX12 ALOX5 ALOX15	7.72e-07	5	89	3	GO:2001300
GeneOntologyBiologicalProcess	synaptic assembly at neuromuscular junction	MYCBP2 SIX4 LARGE1	1.25e-05	11	89	3	GO:0051124
GeneOntologyBiologicalProcess	lipoxygenase pathway	ALOX12 ALOX5 ALOX15	1.25e-05	11	89	3	GO:0019372
GeneOntologyBiologicalProcess	muscle cell development	FLII ADRA1B CAPN3 PRKG1 SIX4 G6PD MYBPC2 LARGE1	1.63e-05	259	89	8	GO:0055001
GeneOntologyBiologicalProcess	calcium-dependent self proteolysis	CAPN8 CAPN3	1.84e-05	2	89	2	GO:1990092
GeneOntologyBiologicalProcess	leukotriene A4 metabolic process	ALOX12 ALOX5	1.84e-05	2	89	2	GO:1901751
GeneOntologyBiologicalProcess	striated muscle cell development	FLII CAPN3 SIX4 MYBPC2 LARGE1	4.17e-05	89	89	5	GO:0055002
GeneOntologyBiologicalProcess	striated muscle cell differentiation	FLII ADRA1B CAPN2 CAPN3 PRKG1 SIX4 G6PD MYBPC2 LARGE1	4.81e-05	391	89	9	GO:0051146
GeneOntologyBiologicalProcess	lipoxin A4 biosynthetic process	ALOX12 ALOX15	5.51e-05	3	89	2	GO:2001303
GeneOntologyBiologicalProcess	ceramide translocation	ABCB1 ABCB4	5.51e-05	3	89	2	GO:0099040
GeneOntologyBiologicalProcess	lipoxin A4 metabolic process	ALOX12 ALOX15	1.10e-04	4	89	2	GO:2001302
GeneOntologyBiologicalProcess	epoxide metabolic process	ALOX12 ALOX5	1.83e-04	5	89	2	GO:0097176
GeneOntologyBiologicalProcess	sphingolipid translocation	ABCB1 ABCB4	1.83e-04	5	89	2	GO:0099039
GeneOntologyBiologicalProcess	lipid biosynthetic process	TMEM150A PIK3CG CAPN2 LPIN2 PRKG1 ST8SIA1 G6PD ALOX12 ALOX5 SEC14L2 ALOX15 LARGE1	1.90e-04	813	89	12	GO:0008610
GeneOntologyBiologicalProcess	long-chain fatty acid biosynthetic process	ALOX12 ALOX5 ALOX15	2.62e-04	29	89	3	GO:0042759
GeneOntologyBiologicalProcess	regulation of anatomical structure size	PLXNA3 FLII SLC6A12 ADRA1B TENM1 STK39 PRKG1 G6PD ALOX5 ALOX15	3.29e-04	618	89	10	GO:0090066
GeneOntologyBiologicalProcess	branchiomotor neuron axon guidance	PLXNA3 MYCBP2	3.81e-04	7	89	2	GO:0021785
GeneOntologyBiologicalProcess	regulation of synaptic assembly at neuromuscular junction	MYCBP2 SIX4	3.81e-04	7	89	2	GO:0008582
GeneOntologyBiologicalProcess	sensory perception of umami taste	CALHM1 TAS1R3	3.81e-04	7	89	2	GO:0050917
GeneOntologyBiologicalProcess	sensory perception of sweet taste	CALHM1 TAS1R3	3.81e-04	7	89	2	GO:0050916
GeneOntologyCellularComponent	synaptic membrane	KCNC3 GPR158 STXBP5 LRFN5 LRFN3 MAGEE1 TENM2 ATP2B3 PTPRT CNTN1	1.53e-04	583	87	10	GO:0097060
GeneOntologyCellularComponent	postsynaptic membrane	KCNC3 GPR158 LRFN5 LRFN3 MAGEE1 TENM2 PTPRT CNTN1	2.85e-04	405	87	8	GO:0045211
HumanPheno	Abnormality of the pineal gland	FLII INSR DKC1 ABCB4	8.37e-06	20	35	4	HP:0012680
HumanPheno	Abnormal pineal volume	INSR DKC1	4.59e-05	2	35	2	HP:0012684
MousePheno	transmission ratio distortion	NAT1 NAT2 CAPN2 CAPN3	2.20e-05	32	73	4	MP:0004179
Domain	LipOase_mml	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	IPR001885
Domain	LIPOXYGENASE_1	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	PS00711
Domain	LipOase_C	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	IPR013819
Domain	Lipoxygenase	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	PF00305
Domain	LIPOXYGENASE_3	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	PS51393
Domain	LIPOXYGENASE_2	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	PS00081
Domain	LipOase	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	IPR000907
Domain	LipOase_Fe_BS	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	IPR020833
Domain	LipOase_CS	ALOX12 ALOX5 ALOX15	2.00e-06	6	88	3	IPR020834
Domain	Calpain_III	CAPN8 CAPN2 CAPN3	2.16e-05	12	88	3	IPR022683
Domain	calpain_III	CAPN8 CAPN2 CAPN3	2.16e-05	12	88	3	SM00720
Domain	C2_III	CAPN8 CAPN2 CAPN3	2.16e-05	12	88	3	IPR033883
Domain	Arylamine_N-AcTrfase	NAT1 NAT2	2.19e-05	2	88	2	IPR001447
Domain	Acetyltransf_2	NAT1 NAT2	2.19e-05	2	88	2	PF00797
Domain	Calpain_domain_III	CAPN8 CAPN2 CAPN3	2.79e-05	13	88	3	IPR022682
Domain	Calpain_III	CAPN8 CAPN2 CAPN3	2.79e-05	13	88	3	PF01067
Domain	Calpain_cysteine_protease	CAPN8 CAPN2 CAPN3	3.54e-05	14	88	3	IPR022684
Domain	FN3	LRFN5 LRFN3 INSR PTPRU PTPRT CNTN1 MYBPC2	4.30e-05	199	88	7	PS50853
Domain	CysPc	CAPN8 CAPN2 CAPN3	4.41e-05	15	88	3	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN8 CAPN2 CAPN3	4.41e-05	15	88	3	IPR001300
Domain	Peptidase_C2	CAPN8 CAPN2 CAPN3	4.41e-05	15	88	3	PF00648
Domain	CALPAIN_CAT	CAPN8 CAPN2 CAPN3	4.41e-05	15	88	3	PS50203
Domain	FN3_dom	LRFN5 LRFN3 INSR PTPRU PTPRT CNTN1 MYBPC2	5.86e-05	209	88	7	IPR003961
Domain	LH2	ALOX12 ALOX5 ALOX15	7.84e-05	18	88	3	SM00308
Domain	fn3	LRFN3 INSR PTPRU PTPRT CNTN1 MYBPC2	1.17e-04	162	88	6	PF00041
Domain	PLAT	ALOX12 ALOX5 ALOX15	1.26e-04	21	88	3	PS50095
Domain	-	ALOX12 ALOX5 ALOX15	1.26e-04	21	88	3	2.60.60.20
Domain	PLAT	ALOX12 ALOX5 ALOX15	1.26e-04	21	88	3	PF01477
Domain	PLAT/LH2_dom	ALOX12 ALOX5 ALOX15	1.26e-04	21	88	3	IPR001024
Domain	Tox-GHH_dom	TENM1 TENM2	1.31e-04	4	88	2	IPR028916
Domain	Ten_N	TENM1 TENM2	1.31e-04	4	88	2	IPR009471
Domain	Ten_N	TENM1 TENM2	1.31e-04	4	88	2	PF06484
Domain	TENEURIN_N	TENM1 TENM2	1.31e-04	4	88	2	PS51361
Domain	Tox-GHH	TENM1 TENM2	1.31e-04	4	88	2	PF15636
Domain	YD	TENM1 TENM2	2.17e-04	5	88	2	IPR006530
Domain	FN3	LRFN3 INSR PTPRU PTPRT CNTN1 MYBPC2	2.41e-04	185	88	6	SM00060
Domain	THIOL_PROTEASE_CYS	CAPN8 CAPN2 CAPN3	2.43e-04	26	88	3	PS00139
Domain	THIOL_PROTEASE_ASN	CAPN8 CAPN2 CAPN3	2.72e-04	27	88	3	PS00640
Domain	THIOL_PROTEASE_HIS	CAPN8 CAPN2 CAPN3	2.72e-04	27	88	3	PS00639
Domain	-	PLXNA3 MYCBP2 TAPBPL LRFN5 LRFN3 INSR PTPRU PTPRT SCN3B CNTN1 MYBPC2	2.77e-04	663	88	11	2.60.40.10
Domain	Pept_cys_AS	CAPN8 CAPN2 CAPN3	3.04e-04	28	88	3	IPR000169
Domain	Ig-like_fold	PLXNA3 MYCBP2 TAPBPL LRFN5 LRFN3 INSR PTPRU PTPRT SCN3B CNTN1 MYBPC2	4.72e-04	706	88	11	IPR013783
Domain	IG	TAPBPL LRFN5 LRFN3 PTPRU PTPRT SCN3B CNTN1 MYBPC2	8.31e-04	421	88	8	SM00409
Domain	Ig_sub	TAPBPL LRFN5 LRFN3 PTPRU PTPRT SCN3B CNTN1 MYBPC2	8.31e-04	421	88	8	IPR003599
Domain	CRAL_TRIO_N	SEC14L3 SEC14L2	1.17e-03	11	88	2	PF03765
Domain	CRAL-bd_toc_tran	SEC14L3 SEC14L2	1.40e-03	12	88	2	IPR001071
Domain	CRAL_TRIO_N	SEC14L3 SEC14L2	1.40e-03	12	88	2	SM01100
Domain	NHL	TENM1 TENM2	1.66e-03	13	88	2	PS51125
Domain	IG_LIKE	TAPBPL LRFN5 LRFN3 PTPRU PTPRT SCN3B CNTN1 MYBPC2	2.20e-03	491	88	8	PS50835
Domain	EMP24_GP25L	SEC14L3 SEC14L2	2.21e-03	15	88	2	PF01105
Domain	CRAL/TRIO_N_dom	SEC14L3 SEC14L2	2.21e-03	15	88	2	IPR011074
Domain	MAM_1	PTPRU PTPRT	2.52e-03	16	88	2	PS00740
Domain	Ig-like_dom	TAPBPL LRFN5 LRFN3 PTPRU PTPRT SCN3B CNTN1 MYBPC2	2.56e-03	503	88	8	IPR007110
Domain	MAM	PTPRU PTPRT	2.85e-03	17	88	2	SM00137
Domain	MAM	PTPRU PTPRT	3.20e-03	18	88	2	PF00629
Domain	MAM_dom	PTPRU PTPRT	3.20e-03	18	88	2	IPR000998
Domain	MAM_2	PTPRU PTPRT	3.20e-03	18	88	2	PS50060
Domain	GOLD_dom	SEC14L3 SEC14L2	3.56e-03	19	88	2	IPR009038
Domain	2OG-FeII_Oxy	ALKBH3 PLOD1	3.56e-03	19	88	2	PF03171
Domain	GOLD	SEC14L3 SEC14L2	3.56e-03	19	88	2	PS50866
Domain	GPCR_3	GPR158 TAS1R3	4.35e-03	21	88	2	IPR000337
Domain	CRAL_TRIO	SEC14L3 SEC14L2	4.35e-03	21	88	2	PF00650
Domain	FE2OG_OXY	ALKBH3 PLOD1	4.35e-03	21	88	2	PS51471
Pathway	WP_METABOLISM_OF_ALPHALINOLENIC_ACID	ALOX12 ALOX5 ALOX15	2.32e-06	6	70	3	M39844
Pathway	REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS	ALOX12 ALOX5 ALOX15	1.07e-04	19	70	3	M27889
Pathway	WP_EICOSANOID_SYNTHESIS	ALOX12 ALOX5 ALOX15	1.69e-04	22	70	3	MM15961
Pathway	REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS	ALOX12 ALOX5 ALOX15	1.69e-04	22	70	3	MM15614
Pathway	WP_OMEGA6FATTY_ACIDS_IN_SENESCENCE	NAT2 ALOX12 ALOX5 ALOX15	1.81e-04	57	70	4	M48332
Pathway	WP_EICOSANOID_SYNTHESIS	ALOX12 ALOX5 ALOX15	1.93e-04	23	70	3	M39382
Pathway	WP_OXYLIPINS_PATHWAYS	ALOX12 ALOX5 ALOX15	2.20e-04	24	70	3	MM17249
Pathway	REACTOME_SYNTHESIS_OF_LIPOXINS_LX	ALOX12 ALOX5	2.41e-04	5	70	2	MM14859
Pathway	REACTOME_BIOSYNTHESIS_OF_E_SERIES_18_S_RESOLVINS	ALOX5 ALOX15	2.41e-04	5	70	2	MM15617
Pathway	BIOCARTA_MRP_PATHWAY	ABCB1 ABCB4	3.60e-04	6	70	2	M22078
Pathway	REACTOME_SYNTHESIS_OF_LIPOXINS_LX	ALOX12 ALOX5	3.60e-04	6	70	2	M27138
Pathway	REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS	ALOX5 ALOX15	3.60e-04	6	70	2	M27890
Pathway	REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS	ALOX5 ALOX15	3.60e-04	6	70	2	MM15615
Pathway	WP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX	ALOX12 ALOX5 ALOX15	3.91e-04	29	70	3	M39858
Pathway	WP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE_WP5122	ALOX12 ALOX5 ALOX15	4.77e-04	31	70	3	M42531
Pathway	REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES	ALOX12 ALOX15	5.02e-04	7	70	2	M27139
Pathway	REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES	ALOX12 ALOX15	5.02e-04	7	70	2	MM14860
Pathway	WP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX	ALOX12 ALOX5 ALOX15	5.75e-04	33	70	3	MM15963
Pathway	WP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE_WP5321	ALOX12 ALOX5 ALOX15	6.28e-04	34	70	3	M48061
Pubmed	Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer.	ALOX12 ALOX5 ALOX15	1.62e-08	3	89	3	22825379
Pubmed	5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.	ALOX12 ALOX5 ALOX15	1.62e-08	3	89	3	18346986
Pubmed	5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.	ALOX12 ALOX5 ALOX15	1.62e-08	3	89	3	30407793
Pubmed	The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.	ALOX12 ALOX5 ALOX15	1.62e-08	3	89	3	8944751
Pubmed	Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.	ALOX12 ALOX5 ALOX15	1.62e-08	3	89	3	15328042
Pubmed	Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.	ALOX12 ALOX5 ALOX15	1.62e-08	3	89	3	23079635
Pubmed	Functional characterization of genetic enzyme variations in human lipoxygenases.	ALOX12 ALOX5 ALOX15	6.47e-08	4	89	3	24282679
Pubmed	Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.	ALOX12 ALOX5 ALOX15	6.47e-08	4	89	3	25698732
Pubmed	Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.	ALOX12 ALOX5 ALOX15	6.47e-08	4	89	3	19509298
Pubmed	Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.	ALOX12 ALOX5 ALOX15	6.47e-08	4	89	3	20592751
Pubmed	Levels of expression of lipoxygenases and cyclooxygenase-2 in human breast cancer.	ALOX12 ALOX5 ALOX15	6.47e-08	4	89	3	12907138
Pubmed	Cloning of novel human SEC14p-like proteins: ligand binding and functional properties.	SEC14L3 PIK3CG SEC14L2	6.47e-08	4	89	3	12757856
Pubmed	Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease.	NAT1 NAT2 INSR	1.61e-07	5	89	3	33296651
Pubmed	Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.	ALOX12 ALOX5 ALOX15	1.61e-07	5	89	3	36599368
Pubmed	mRNA levels of enzymes and receptors implicated in arachidonic acid metabolism in gliomas.	ALOX12 ALOX5 ALOX15	3.22e-07	6	89	3	20382140
Pubmed	Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice.	ALOX12 ALOX5 ALOX15	3.22e-07	6	89	3	25313597
Pubmed	Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.	IGF2R ALOX5 ALOX15	3.22e-07	6	89	3	32234475
Pubmed	Lack of effect of common single nucleotide polymorphisms in leukotriene pathway genes on platelet reactivity in patients with diabetes.	ALOX12 ALOX5 ALOX15	3.22e-07	6	89	3	23828562
Pubmed	Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.	ALOX12 ALOX5 ALOX15	5.63e-07	7	89	3	17873277
Pubmed	Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes.	NAT1 NAT2 ABCB1	8.99e-07	8	89	3	17259654
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	NAT1 NAT2 IGF2R INSR ALOX12 ALOX5 SEC14L2 ALOX15 ABCB1	1.39e-06	421	89	9	19692168
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	NAT2 IGF2R PIK3CG CAPN2 ALOX12 ALOX5 ABCB1 ABCB4	3.45e-06	351	89	8	20453000
Pubmed	Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.	ABCB1 ABCB4	6.48e-06	2	89	2	10488067
Pubmed	Are polymorphisms of N-acetyltransferase genes susceptible to primary liver cancer in Luoyang, China?	NAT1 NAT2	6.48e-06	2	89	2	15770721
Pubmed	Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study.	NAT1 NAT2	6.48e-06	2	89	2	19549810
Pubmed	Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells.	ALOX12 ALOX15	6.48e-06	2	89	2	30792307
Pubmed	Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.	ALOX12 ALOX15	6.48e-06	2	89	2	25251155
Pubmed	Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.	NAT1 NAT2	6.48e-06	2	89	2	17656365
Pubmed	A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense.	ALOX12 ALOX15	6.48e-06	2	89	2	15708862
Pubmed	N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis.	NAT1 NAT2	6.48e-06	2	89	2	12135032
Pubmed	Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver.	NAT1 NAT2	6.48e-06	2	89	2	28888949
Pubmed	Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.	ABCB1 ABCB4	6.48e-06	2	89	2	21705081
Pubmed	The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.	ABCB1 ABCB4	6.48e-06	2	89	2	10552998
Pubmed	Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma.	NAT1 NAT2	6.48e-06	2	89	2	17522066
Pubmed	Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.	ABCB1 ABCB4	6.48e-06	2	89	2	28441502
Pubmed	Genetic dissection of the function of mammalian P-glycoproteins.	ABCB1 ABCB4	6.48e-06	2	89	2	9196326
Pubmed	The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma.	ALOX12 ALOX5	6.48e-06	2	89	2	30941737
Pubmed	Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2.	NAT1 NAT2	6.48e-06	2	89	2	1559981
Pubmed	Genetic polymorphisms of arylamine N-acetyltransferases 1 and 2 and the likelihood of developing pediatric acute lymphoblastic leukemia.	NAT1 NAT2	6.48e-06	2	89	2	29214875
Pubmed	Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.	ABCB1 ABCB4	6.48e-06	2	89	2	22184139
Pubmed	N-acetyltransferase 1 and 2 polymorphisms and risk of diabetes mellitus type 2 in a Saudi population.	NAT1 NAT2	6.48e-06	2	89	2	26409796
Pubmed	Enhancement role of host 12/15-lipoxygenase in melanoma progression.	ALOX12 ALOX15	6.48e-06	2	89	2	23664097
Pubmed	Lipoxygenase metabolites are mediators of PTH-dependent human osteoblast growth.	ALOX12 ALOX15	6.48e-06	2	89	2	18187376
Pubmed	Effects of microRNA-217 on proliferation, apoptosis, and autophagy of hepatocytes in rat models of CCL4-induced liver injury by targeting NAT2.	NAT1 NAT2	6.48e-06	2	89	2	30417525
Pubmed	Isolation and expression of a complementary DNA that confers multidrug resistance.	ABCB1 ABCB4	6.48e-06	2	89	2	3022150
Pubmed	Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.	NAT1 NAT2	6.48e-06	2	89	2	11266080
Pubmed	N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.	NAT1 NAT2	6.48e-06	2	89	2	19379125
Pubmed	Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice.	NAT1 NAT2	6.48e-06	2	89	2	29237750
Pubmed	Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.	ABCB1 ABCB4	6.48e-06	2	89	2	2570420
Pubmed	MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.	ABCB1 ABCB4	6.48e-06	2	89	2	8898203
Pubmed	Polymorphisms in the human ALOX12 and ALOX15 genes are associated with peak bone mineral density in Chinese nuclear families.	ALOX12 ALOX15	6.48e-06	2	89	2	22089472
Pubmed	Genetic regulation of aromatic amine N-acetylation in inbred mice.	NAT1 NAT2	6.48e-06	2	89	2	6976963
Pubmed	Update on consensus arylamine N-acetyltransferase gene nomenclature.	NAT1 NAT2	6.48e-06	2	89	2	10862519
Pubmed	12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.	ALOX12 ALOX15	6.48e-06	2	89	2	19787041
Pubmed	Glucocorticoid receptor-mediated transcriptional regulation of N-acetyltransferase 1 gene through distal promoter.	NAT1 NAT2	6.48e-06	2	89	2	22644701
Pubmed	Molecular genetic basis of rapid and slow acetylation in mice.	NAT1 NAT2	6.48e-06	2	89	2	1875909
Pubmed	Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.	ABCB1 ABCB4	6.48e-06	2	89	2	2473069
Pubmed	NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant.	NAT1 NAT2	6.48e-06	2	89	2	15142281
Pubmed	Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.	ABCB1 ABCB4	6.48e-06	2	89	2	28274756
Pubmed	5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion.	NAT1 NAT2	6.48e-06	2	89	2	24205029
Pubmed	Isotope sensitive branching and kinetic isotope effects in the reaction of deuterated arachidonic acids with human 12- and 15-lipoxygenases.	ALOX12 ALOX15	6.48e-06	2	89	2	18547056
Pubmed	Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism.	NAT1 NAT2	6.48e-06	2	89	2	17961509
Pubmed	Sequence variants of NAT1 and NAT2 and other xenometabolic genes and risk of lung and aerodigestive tract cancers in Central Europe.	NAT1 NAT2	6.48e-06	2	89	2	18199719
Pubmed	Polymorphisms of arylamine N-acetyltransferase (NAT1 and NAT2) and larynx cancer susceptibility.	NAT1 NAT2	6.48e-06	2	89	2	12037388
Pubmed	12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet.	ALOX12 ALOX15	6.48e-06	2	89	2	18780776
Pubmed	N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer.	NAT1 NAT2	6.48e-06	2	89	2	19898993
Pubmed	A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.	ABCB1 ABCB4	6.48e-06	2	89	2	19185004
Pubmed	Effects of genetic polymorphisms of N-Acetyltransferase on trichloroethylene-induced hypersensitivity dermatitis among exposed workers.	NAT1 NAT2	6.48e-06	2	89	2	19834256
Pubmed	Carcinogen metabolism, cigarette smoking, and breast cancer risk: a Bayes model averaging approach.	NAT1 NAT2	6.48e-06	2	89	2	21080951
Pubmed	Association of arylamine N-acetyltransferase (NAT1 and NAT2) genotypes with urinary bladder cancer risk.	NAT1 NAT2	6.48e-06	2	89	2	14564055
Pubmed	Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer.	NAT1 NAT2	6.48e-06	2	89	2	18006927
Pubmed	The evolutionary hypothesis of reaction specificity of mammalian ALOX15 orthologs.	ALOX12 ALOX15	6.48e-06	2	89	2	30237084
Pubmed	Human ALOX12, but not ALOX15, is associated with BMD in white men and women.	ALOX12 ALOX15	6.48e-06	2	89	2	16598376
Pubmed	Expression of 12/15-lipoxygenase attenuates intracellular lipid deposition during in vitro foam cell formation.	ALOX12 ALOX15	6.48e-06	2	89	2	15681297
Pubmed	Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.	NAT1 NAT2	6.48e-06	2	89	2	25798622
Pubmed	Common polymorphisms in 5-lipoxygenase and 12-lipoxygenase genes and the risk of incident, sporadic colorectal adenoma.	ALOX12 ALOX5	6.48e-06	2	89	2	17236225
Pubmed	RNAi-mediated knock-down of arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition.	NAT1 NAT2	6.48e-06	2	89	2	21347396
Pubmed	Expression of lipoxygenase in human prostate cancer and growth reduction by its inhibitors.	ALOX12 ALOX5	6.48e-06	2	89	2	15010818
Pubmed	Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.	ABCB1 ABCB4	6.48e-06	2	89	2	18215618
Pubmed	Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells.	NAT1 NAT2	6.48e-06	2	89	2	28003464
Pubmed	Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk.	NAT1 NAT2	6.48e-06	2	89	2	11751443
Pubmed	Arylamine N-acetyltransferase 2 expression in the developing heart.	NAT1 NAT2	6.48e-06	2	89	2	15872051
Pubmed	N-acetyltransferase polymorphisms are associated with risk of lymphoma subtypes.	NAT1 NAT2	6.48e-06	2	89	2	25689677
Pubmed	Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.	ALOX12 ALOX15	6.48e-06	2	89	2	29184033
Pubmed	Association of prostate cancer with rapid N-acetyltransferase 1 (NAT1*10) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control study.	NAT1 NAT2	6.48e-06	2	89	2	12355549
Pubmed	Tomosyn interacts with the SUMO E3 ligase PIASγ.	PIAS4 STXBP5	6.48e-06	2	89	2	24614299
Pubmed	Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice.	ALOX12 ALOX15	6.48e-06	2	89	2	10330425
Pubmed	An N-ethyl-N-nitrosourea-induced mutation in N-acetyltransferase 1 in mice.	NAT1 NAT2	6.48e-06	2	89	2	18373979
Pubmed	Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma.	NAT1 NAT2	6.48e-06	2	89	2	17537267
Pubmed	Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium.	NAT1 NAT2	6.48e-06	2	89	2	23160945
Pubmed	Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.	ALOX5 ALOX15	6.48e-06	2	89	2	22516296
Pubmed	Structural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts.	NAT1 NAT2	6.48e-06	2	89	2	15853926
Pubmed	In silico sequence analysis of arylamine N-acetyltransferases: evidence for an absence of lateral gene transfer from bacteria to vertebrates and first description of paralogs in bacteria.	NAT1 NAT2	6.48e-06	2	89	2	12054539
Pubmed	Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes.	ALOX12 ALOX15	6.48e-06	2	89	2	18755188
Pubmed	Acetylation genotype and the genetic susceptibility to prostate cancer in a southern European population.	NAT1 NAT2	6.48e-06	2	89	2	15717312
Pubmed	Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferases.	NAT1 NAT2	6.48e-06	2	89	2	1676262
Pubmed	Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.	ALOX12 ALOX15	6.48e-06	2	89	2	25293588
Pubmed	Arylamine N-acetyltransferases: a structural perspective.	NAT1 NAT2	6.48e-06	2	89	2	23517104
Pubmed	No apparent association between NAT1 and NAT2 genotypes and risk of stomach cancer.	NAT1 NAT2	6.48e-06	2	89	2	12692115
Pubmed	What have we learnt thus far from mice with disrupted P-glycoprotein genes?	ABCB1 ABCB4	6.48e-06	2	89	2	8763339
Cytoband	Xq28	PLXNA3 MAGEA10 DKC1 G6PD ATP2B3	2.50e-05	176	89	5	Xq28
Cytoband	Ensembl 112 genes in cytogenetic band chrXq28	PLXNA3 MAGEA10 DKC1 G6PD ATP2B3	6.20e-05	213	89	5	chrXq28
Cytoband	10q11.2	PRKG1 ALOX5	3.33e-04	14	89	2	10q11.2
GeneFamily	Arachidonate lipoxygenases	ALOX12 ALOX5 ALOX15	8.80e-07	6	65	3	407
GeneFamily	Fibronectin type III domain containing	LRFN5 LRFN3 INSR PTPRU PTPRT CNTN1 MYBPC2	1.69e-06	160	65	7	555
GeneFamily	C2 domain containing\|Calpains	CAPN8 CAPN2 CAPN3	1.96e-05	15	65	3	975
GeneFamily	Arylamine N-acetyltransferases	NAT1 NAT2	3.81e-05	3	65	2	1133
GeneFamily	SEC14 family\|PRELI domain containing	SEC14L3 SEC14L2	1.89e-04	6	65	2	1063
GeneFamily	ATP binding cassette subfamily B	ABCB1 ABCB4	6.85e-04	11	65	2	806
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRU PTPRT	2.56e-03	21	65	2	813
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	LRFN5 LRFN3 CNTN1 MYBPC2	2.69e-03	161	65	4	593
GeneFamily	MAGE family	MAGEA10 MAGEE1	9.09e-03	40	65	2	1136
Coexpression	HOSHIDA_LIVER_CANCER_SUBCLASS_S3	SLC6A12 MYO1E ASL INSR LPIN2 NNMT PCCA ABCB4	3.52e-06	266	89	8	M1286
Coexpression	CARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_DN	SEC14L3 NAT2 ADRA1B TMEM176B TAPBPL GPR158 ASL LPIN2 TENM1 OGDHL NNMT PCCA SEC14L2 STARD5 WDR72	2.03e-05	1257	89	15	M45034
Coexpression	GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN	IGF2R MYCBP2 STXBP5 RAB7B IFIT2 ALOX15	3.18e-05	177	89	6	M7632
Coexpression	CAIRO_HEPATOBLASTOMA_DN	NAT2 ASL LPIN2 TENM1 OGDHL NNMT STARD5	3.56e-05	267	89	7	M13449
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ARFGEF3 MYCBP2 GPR158 LRFN5 TENM1 TENM2 ATP2B3	1.10e-07	190	89	7	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ARFGEF3 MYCBP2 GPR158 LRFN5 TENM2 ATP2B3	2.01e-06	186	89	6	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADRA1B LRFN5 INSR PRKG1 CNTN1 LARGE1	2.08e-06	187	89	6	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 PIK3CG KREMEN2 OGDHL ALOX5 PTPRT	2.35e-06	191	89	6	54f07e4de61735051498846afb44b1798bed8144
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMEM176B TENM1 HSPB2 HCRTR2 WDR72	3.80e-06	117	89	5	0602bbad908cb28c5093b74d717da5f2af577943
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARFGEF3 PLXNA3 KCNC3 KREMEN2 SORD	1.50e-05	155	89	5	be575a0096415705dba425002247289ff8f89474
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 PIK3CG CAPN3 OGDHL ALOX5	1.54e-05	156	89	5	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	PND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IMPG1 PIK3CG STXBP5 RAB7B ALOX5	1.74e-05	160	89	5	4480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 PIK3CG STXBP5 OGDHL ALOX5	1.85e-05	162	89	5	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 PIK3CG OGDHL ALOX5 PTPRT	2.20e-05	168	89	5	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 PTPRU HCRTR2 SCN3B ABCB1	2.20e-05	168	89	5	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 PIK3CG OGDHL ALOX5 PTPRT	2.27e-05	169	89	5	05e12524d68d409fed386ffad233305683b4575b
ToppCell	facs-Heart-LV-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN8 CRYBG2 KREMEN2 ITGAD CNTN1	2.33e-05	170	89	5	71e5e27c3c4e6cc8dc9b063bd51c21c049f54416
ToppCell	facs-Heart-LV-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN8 CRYBG2 KREMEN2 ITGAD CNTN1	2.33e-05	170	89	5	255bbbd00d0e17510c5a8c5faa43ed90d887a9de
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CG OGDHL ALOX12 ALOX5 CNTN1	2.33e-05	170	89	5	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	severe_influenza-B_cell\|World / disease group, cell group and cell class (v2)	PLXNA3 ABCB1 STARD5 ABCB4	2.68e-05	86	89	4	7b595bcba4bcb72b7de7c06e19f690f0c739c529
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 PTPRU HCRTR2 SCN3B ABCB1	2.83e-05	177	89	5	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 PTPRU HCRTR2 SCN3B ABCB1	2.91e-05	178	89	5	431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM176B TAS1R3 PIK3CG OGDHL ALOX5	2.99e-05	179	89	5	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	INSR SLC22A11 TENM1 ABCB1 WDR72	3.07e-05	180	89	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INSR SLC22A11 TENM1 SORD WDR72	3.32e-05	183	89	5	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	CAPN8 ARFGEF3 TMEM176B TLL1 INSR	3.59e-05	186	89	5	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ARFGEF3 MYCBP2 TENM1 TENM2 ATP2B3	4.17e-05	192	89	5	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	INSR PRKG1 PCCA WDR72 LARGE1	4.17e-05	192	89	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAPN8 ARFGEF3 ADRA1B KCNC3 INSR	4.83e-05	198	89	5	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLXNA3 ASL KREMEN2 CAPN2 PLOD1	4.94e-05	199	89	5	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADRA1B OGDHL TENM2 PTPRT SCN3B	5.06e-05	200	89	5	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARFGEF3 CAPN2 CPLANE1 ALOX15 SORD	5.06e-05	200	89	5	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPR158 LRFN5 TLL1 TENM1 PTPRT	5.06e-05	200	89	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPR158 LRFN5 TLL1 TENM1 PTPRT	5.06e-05	200	89	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADRA1B OGDHL TENM2 PTPRT SCN3B	5.06e-05	200	89	5	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	MYCBP2 TENM1 TENM2 PTPRT SCN3B	5.06e-05	200	89	5	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPR158 LRFN5 TLL1 TENM1 PTPRT	5.06e-05	200	89	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADRA1B OGDHL TENM2 PTPRT SCN3B	5.06e-05	200	89	5	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPR158 LRFN5 TLL1 TENM1 PTPRT	5.06e-05	200	89	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPR158 LRFN5 TLL1 TENM1 PTPRT	5.06e-05	200	89	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GPR158 LRFN5 TLL1 TENM1 PTPRT	5.06e-05	200	89	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	severe_influenza-B_cell\|severe_influenza / disease group, cell group and cell class (v2)	PLXNA3 ABCB1 STARD5 ABCB4	1.27e-04	128	89	4	92b250186d6bb08ce4f2f5cc4fb93928f6b92d3a
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MEP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	STXBP5 PTPRU GSTO2 PCCA	1.64e-04	137	89	4	0bb5cccc31e7c44d44a2db3f59b68f9a81503151
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC6A12 LRFN5 KATNB1 GSTO2	1.89e-04	142	89	4	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1\|Striatum / BrainAtlas - Mouse McCarroll V32	RAB7B GSTO2 ITGAD ALOX5	1.99e-04	144	89	4	9d6133558728fa148050eb4f0be33756d71310b0
ToppCell	Club_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ARFGEF3 LRFN3 SORD WDR72	2.15e-04	147	89	4	5a824c89e4d045af465d7333275f8191fb29b041
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P1\|Thalamus / BrainAtlas - Mouse McCarroll V32	RAB7B GSTO2 ITGAD ALOX5	2.15e-04	147	89	4	a21b63d0d3aec9ffadf3fac833a0a24da58a95bf
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN3 ALOX5 ALOX15 ABCB4	2.63e-04	155	89	4	c648512305166d2a2f0e284c127bc802af908071
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIN1 LRFN3 PTPRU STARD5	2.77e-04	157	89	4	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MYO1E MAGEE1 GSTO2 ABCB1	2.77e-04	157	89	4	542944030cd9b3f3559e64f9f6598694d74003c0
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADRA1B KREMEN2 RAB7B HSPB2	2.97e-04	160	89	4	68b477525eeef99430382ff0a6745cac91364bc2
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 OGDHL ALOX5 PTPRT	3.04e-04	161	89	4	f5df8c6a340d5026726804b103e32137f363ca40
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 ASL NNMT SEC14L2	3.04e-04	161	89	4	274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYCBP2 ALOX5 SEC14L2 ALOX15	3.12e-04	162	89	4	d712bc31840ad1523e3dbf884acbb428a8995001
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CAPN8 ARFGEF3 ADRA1B STK39	3.12e-04	162	89	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 ASL NNMT SEC14L2	3.19e-04	163	89	4	03d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 ASL NNMT SEC14L2	3.19e-04	163	89	4	1c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CAPN8 LRFN5 CST4 ALOX15	3.19e-04	163	89	4	22fa5d017ff796394394d952ec151e2d1beb8248
ToppCell	droplet-Liver-Hepatocytes-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 ASL NNMT SEC14L2	3.19e-04	163	89	4	7e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM176B IMPG1 RAB7B ALOX5	3.34e-04	165	89	4	47e716ce8dc283d406352c1909e09362fcb9e3a3
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM176B IMPG1 RAB7B ALOX5	3.34e-04	165	89	4	fe2135fdacf3807eb4b5ea5e790febfb8cd54335
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CRYBG2 SLC22A11 TENM2 ALOX15	3.50e-04	167	89	4	4b6853efefea5178280ba7c31facda0fbd1cc469
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	PIK3CG TLL1 ST8SIA1 ITGAD	3.50e-04	167	89	4	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RAB7B ITGAD ALOX5	3.57e-04	69	89	3	3da27f504e82277fa4a8fb67d60fc26dee0a414f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1B SLC22A11 SORD WDR72	3.58e-04	168	89	4	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	10x3'2.3-week_17-19-Myeloid_macrophage-stroma-osteoclast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ARFGEF3 CAPN2 NNMT HCRTR2	3.58e-04	168	89	4	1993e7fb6d7291d448219c813cb968ddad270bb5
ToppCell	Lymphoid-Lymphoid-T_cells_(Cd8+_T_cell)\|Lymphoid / shred on cell class and cell subclass (v4)	FLII TMEM176B KREMEN2 SIX4	3.74e-04	170	89	4	20fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM176B PIK3CG OGDHL ALOX5	3.74e-04	170	89	4	c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM176B STXBP5 RAB7B ABCB1	3.74e-04	170	89	4	f664c7559e383b37845c123e41a3be316d869ba0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM176B STXBP5 RAB7B ABCB1	3.74e-04	170	89	4	0272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 PTPRU HCRTR2 ABCB1	3.74e-04	170	89	4	417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRFN5 PRKG1 ATP2B3 STARD5	3.82e-04	171	89	4	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 STXBP5 PTPRU ALOX5	3.82e-04	171	89	4	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 STXBP5 PTPRU ALOX5	3.82e-04	171	89	4	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	ADRA1B RAB7B PRKG1 LARGE1	3.82e-04	171	89	4	cafcb7714110cb361808dbe4b9a4963bb71f5129
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 PTPRU G6PD ALOX5	3.82e-04	171	89	4	95e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A12 PTPRU G6PD ALOX5	3.82e-04	171	89	4	36657e277aad75c4f157c1726c48e09b5836cf37
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRFN5 PRKG1 ATP2B3 STARD5	3.82e-04	171	89	4	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KATNB1 IFIT2 TENT2 SORD	3.91e-04	172	89	4	ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ARFGEF3 OGDHL RAB7B ALOX15	4.00e-04	173	89	4	e05cddf5bf63cf419343ff229453327519765be8
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ARFGEF3 TLL1 OGDHL ALOX15	4.00e-04	173	89	4	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TLL1 PRKG1 ST8SIA1 PTPRT	4.00e-04	173	89	4	ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ARFGEF3 OGDHL RAB7B ALOX15	4.00e-04	173	89	4	74ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CAPN8 TLL1 INSR SIX4	4.00e-04	173	89	4	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ARFGEF3 TLL1 OGDHL ALOX15	4.00e-04	173	89	4	3aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Basophil\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN3 ALOX5 ALOX15 ABCB4	4.00e-04	173	89	4	2cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN3 ALOX5 ALOX15 ABCB4	4.00e-04	173	89	4	11d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150A RAB7B IFIT2 SCN3B	4.00e-04	173	89	4	fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 HCRTR2 SCN3B ABCB1	4.00e-04	173	89	4	95c723b09254ae7131fe5ba0841472502e83269b
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	IGF2R TLL1 PRKG1 PLOD1	4.08e-04	174	89	4	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP2B3 ALOX15 MYBPC2 WDR72	4.08e-04	174	89	4	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN3 LPIN2 ALOX12 ABCB4	4.08e-04	174	89	4	a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN3 LPIN2 ALOX12 ABCB4	4.08e-04	174	89	4	6cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TCL1B KREMEN2 ALOX5 ABCB4	4.08e-04	174	89	4	183ff6b93b7fbe43d83e12427e234bd7d8745961
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN3 LPIN2 ALOX12 ABCB4	4.08e-04	174	89	4	4b8bc5568e36031c8ecf001bb646809038c23919
ToppCell	(03)_Secretory-(0)_uninjured\|(03)_Secretory / shred by cell type and Timepoint	SEC14L3 ARFGEF3 SEC14L2 ALOX15	4.08e-04	174	89	4	ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB7B NNMT CNTN1 MYBPC2	4.08e-04	174	89	4	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	11.5-Distal-Immune-Hematopoietic,_B_Cells\|Distal / Age, Tissue, Lineage and Cell class	TCL1B KREMEN2 ALOX12 ALOX5	4.17e-04	175	89	4	d8ca8fbe5309dab293c335b32f1b138edfdd0b07
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 PTPRU HCRTR2 ABCB1	4.17e-04	175	89	4	90e29945aa861082c94bb4f331161adc3a6ef899
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	CRYBG2 MYCBP2 CAPN2 ALOX12	4.17e-04	175	89	4	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CAPN3 PRKG1 NNMT HSPB2	4.17e-04	175	89	4	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 PTPRU HCRTR2 ABCB1	4.26e-04	176	89	4	e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	CAPN8 ARFGEF3 INSR SIX4	4.36e-04	177	89	4	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAT1 SLC6A12 INSR SLC22A11	4.36e-04	177	89	4	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
Computational	Genes in the cancer module 7.	PLXNA3 ZC3H14 ADRA1B CDK13 CAPN3 ALOX12 ALOX15 MYBPC2	5.66e-05	239	61	8	MODULE_7
Drug	sulfapyridine	NAT1 NAT2 ALOX12 ALOX5 ALOX15	6.14e-08	27	89	5	CID000005336
Drug	AC1LCT6N	NAT1 NAT2 CAPN3 ALOX12	1.05e-07	12	89	4	CID000606283
Drug	8R-HpETE	CDK13 ALOX12 ALOX5 ALOX15	2.88e-07	15	89	4	CID005283170
Drug	sinensetin	ALOX12 ALOX5 ALOX15 ABCB1	3.83e-07	16	89	4	CID000145659
Drug	thiobarbituric acid	ITGAD PLOD1 G6PD ALOX12 ALOX5 ALOX15 SORD	4.07e-07	118	89	7	CID002723628
Drug	N-(3-phenoxycinnamyl)acetohydroxamic acid	ALOX12 ALOX5 ALOX15	5.74e-07	5	89	3	ctd:C056614
Drug	artonin E	ALOX12 ALOX5 ALOX15	5.74e-07	5	89	3	CID005481962
Drug	AC1O5PL5	CDK13 ALOX12 ALOX5 ALOX15	6.40e-07	18	89	4	CID006438380
Drug	alpha-ketoglutarate	GIN1 ALKBH3 OGDHL PLOD1 PCCA G6PD ALOX12 SEC14L2 ALOX15	6.79e-07	254	89	9	CID000000051
Drug	succinate	ASL SLC22A11 ALKBH3 OGDHL PLOD1 G6PD ATP2B3 ALOX12 ALOX15 ABCB1	8.42e-07	339	89	10	CID000001110
Drug	Hydroxyacetylaminofluorene	NAT1 NAT2 ABCB1	1.15e-06	6	89	3	ctd:D006881
Drug	CPHU	ALOX12 ALOX5 ALOX15	1.15e-06	6	89	3	CID000124471
Drug	BW A797C	ALOX12 ALOX5 ALOX15	1.15e-06	6	89	3	CID006439067
Drug	isamoxole	ALOX12 ALOX5 ALOX15	1.15e-06	6	89	3	CID000042118
Drug	1-oleoyl-2-DHA-PC	ALOX12 ALOX5 ALOX15	1.15e-06	6	89	3	CID006438829
Drug	5-ASA	NAT1 NAT2 ALOX12 ALOX5 ALOX15	1.50e-06	50	89	5	CID000004075
Drug	L-656,224	ALOX12 ALOX5 ALOX15 ABCB1	1.82e-06	23	89	4	CID000128132
Drug	12-IODE	ALOX12 ALOX5 ALOX15	2.00e-06	7	89	3	CID006450050
Drug	AC1L9K72	DDHD1 LPIN2 ALOX12 ALOX5 ALOX15 CNTN1 ABCB1 STARD5 ABCB4	2.03e-06	290	89	9	CID000446872
Drug	3-chlorocatechol	NAT1 NAT2 ALOX12 ALOX15	3.05e-06	26	89	4	CID000019928
Drug	colneleic acid	ALOX12 ALOX5 ALOX15	3.19e-06	8	89	3	CID006441681
Drug	Cgs 22745	ALOX12 ALOX5 ALOX15	3.19e-06	8	89	3	CID006439321
Drug	TEI-8005	ALOX12 ALOX5 ALOX15	3.19e-06	8	89	3	CID006438655
Drug	thiopyrylium	ALOX5 ABCB1 ABCB4	3.19e-06	8	89	3	CID011344401
Drug	CDNQ	ALOX12 ALOX5 ALOX15	3.19e-06	8	89	3	CID000126468
Drug	htyA	ALOX12 ALOX5 ALOX15	3.19e-06	8	89	3	CID000152267
Drug	2,3-dihydroxybiphenyl	NAT1 NAT2 ALOX12 ALOX15	4.16e-06	28	89	4	CID000000254
Drug	14,15-leukotriene A4	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID006439604
Drug	U-56467	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID006439532
Drug	8,15-diHPETE	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID005283181
Drug	T 0757	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID006439291
Drug	13-hydroxylinoleic acid	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID006438633
Drug	AC1NSXHC	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID005371969
Drug	S 19812	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID005744460
Drug	octadeca-9,12-dien-1-ol	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID000068168
Drug	U-66,855	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID000127235
Drug	ODYA	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID000001931
Drug	A-78773	ALOX12 ALOX5 ALOX15	4.77e-06	9	89	3	CID000071460
Drug	Vitamin E	SEC14L3 ALOX5 SEC14L2	6.79e-06	10	89	3	DB00163
Drug	EP 10045	ALOX12 ALOX5 ALOX15	6.79e-06	10	89	3	CID000127575
Drug	9-HPODE	ALOX12 ALOX5 ALOX15	6.79e-06	10	89	3	CID000001928
Drug	1,4-pentadiene	ALOX12 ALOX5 ALOX15	6.79e-06	10	89	3	CID000011587
Drug	AC1L1TSE	ALOX12 ALOX5 ALOX15 ABCB1 ABCB4	9.27e-06	72	89	5	CID000060719
Drug	LTE5	ALOX12 ALOX5 ALOX15	9.31e-06	11	89	3	CID006439533
Drug	acetone phenylhydrazone	ALOX12 ALOX5 ALOX15	9.31e-06	11	89	3	CID000066026
Drug	Ity A	ALOX12 ALOX5 ALOX15	9.31e-06	11	89	3	CID000188274
Drug	BW A137C	ALOX12 ALOX5 ALOX15	9.31e-06	11	89	3	CID000129265
Drug	nonenal	ALOX12 ALOX5 ALOX15	1.24e-05	12	89	3	CID003015503
Drug	Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A	CDK13 TENM1 OGDHL CPLANE1 ALOX12 SEC14L2 HCRTR2	1.36e-05	200	89	7	6329_UP
Drug	4-iodoaniline	NAT1 NAT2	1.51e-05	2	89	2	ctd:C013067
Drug	N-hydroxy-2-aminofluorene	NAT1 NAT2	1.51e-05	2	89	2	ctd:C001368
Drug	4-bromoaniline	NAT1 NAT2	1.51e-05	2	89	2	ctd:C023621
Drug	bromoacetanilide	NAT1 NAT2	1.51e-05	2	89	2	ctd:C056005
Drug	1,9-dideoxyforskolin	ABCB1 ABCB4	1.51e-05	2	89	2	ctd:C047983
Drug	acetone phenylhydrazone	ALOX12 ALOX5	1.51e-05	2	89	2	ctd:C045543
Drug	2-(bromoacetylamino)fluorene	NAT1 NAT2	1.51e-05	2	89	2	ctd:C075748
Drug	AC1NR1Q2	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID005283190
Drug	AC1L1BGZ	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID000001435
Drug	CV-6504	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID000093543
Drug	9-HETE	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID000001926
Drug	hypolaetin	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID005281648
Drug	ICI207968	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID000129095
Drug	AC1O4E1A	ALOX12 ALOX5 ALOX15	1.61e-05	13	89	3	CID006365736
Drug	benzidine	NAT1 NAT2 ALOX12 ALOX5 ALOX15	1.65e-05	81	89	5	CID000007111
Drug	AC1NR1LB	ALOX12 ALOX5 ALOX15	2.04e-05	14	89	3	CID005283131
Drug	aspartimide	NAT1 NAT2 INSR	2.04e-05	14	89	3	CID000188987
Drug	oxphaman	ALOX12 ALOX5 ALOX15	2.04e-05	14	89	3	CID005464022
Drug	timegadine	ALOX12 ALOX5 ALOX15	2.04e-05	14	89	3	CID000068902
Drug	17-HdoHE	ALOX12 ALOX5 ALOX15	2.04e-05	14	89	3	CID006439179
Drug	5-HEPE	ALOX12 ALOX5 ALOX15	2.04e-05	14	89	3	CID000001766
Drug	clotrimazole	GSTO2 ATP2B3 ALOX12 ALOX5 ALOX15 ABCB1	2.09e-05	143	89	6	CID000002812
Drug	luminol	LPIN2 G6PD ALOX12 ALOX5 ALOX15	2.34e-05	87	89	5	CID000010638
Drug	Hex-3-enyl acetate	ALOX12 ALOX5 ALOX15	2.54e-05	15	89	3	CID000015574
Drug	8(S),15(S)-diHETE	ALOX12 ALOX5 ALOX15	2.54e-05	15	89	3	CID000001897
Drug	13-HpOTrE	ALOX12 ALOX5 ALOX15	2.54e-05	15	89	3	CID005282866
Drug	AC1NR1M2	ALOX12 ALOX5 ALOX15	3.12e-05	16	89	3	CID005283140
Drug	12R-HETrE	ALOX12 ALOX5 ALOX15	3.12e-05	16	89	3	CID005283149
Drug	peroxylinolenic acid	ALOX12 ALOX5 ALOX15	3.12e-05	16	89	3	CID006439905
Drug	PGD3	G6PD ALOX12 ALOX15	3.12e-05	16	89	3	CID005282260
Drug	hex-3-enal	ALOX12 ALOX5 ALOX15	3.12e-05	16	89	3	CID000023234
Drug	A63162	ALOX12 ALOX5 ALOX15	3.12e-05	16	89	3	CID000121876
Drug	AR N	FLII ASL G6PD ABCB4	3.42e-05	47	89	4	CID004473080
Drug	5,15-diHETE	ALOX12 ALOX5 ALOX15	3.77e-05	17	89	3	CID005283158
Drug	cirsiliol	ALOX12 ALOX5 ALOX15	3.77e-05	17	89	3	CID000160237
Drug	2 CS	ALOX12 ALOX5 ALOX15	3.77e-05	17	89	3	CID000060923
Drug	7,7-dimethyleicosadienoic acid	ALOX12 ALOX5 ALOX15	3.77e-05	17	89	3	CID000001877
Drug	trifluoperazine	ADRA1B MYO1E PRKG1 ATP2B3 ALOX12 ALOX5 ALOX15 ABCB1	4.01e-05	324	89	8	CID000005566
Drug	arabinosyladenine	NAT1 ZC3H14 ADRA1B IGF2R FARS2 PIK3CG CAPN3 PRKG1 NNMT G6PD ATP2B3 ABCB1	4.05e-05	762	89	12	CID000000191
Drug	1-methyladenine	CDK13 ALKBH3 ALOX12 ALOX15	4.38e-05	50	89	4	CID000078821
Drug	glutathione reduced	NAT1 NAT2 GSTO2 G6PD ALOX12 ALOX5 ALOX15 ABCB1 SORD ABCB4	4.48e-05	534	89	10	CID000000745
Drug	FPL 57231	ALOX12 ALOX5 ALOX15	4.52e-05	18	89	3	CID000122212
Drug	diphenyl disulfide	ALOX12 ALOX5 ALOX15	4.52e-05	18	89	3	CID000013436
Drug	3-nonenal	ALOX12 ALOX5 ALOX15	4.52e-05	18	89	3	CID005283336
Drug	BW540C	ALOX12 ALOX5 ALOX15	4.52e-05	18	89	3	CID000134372
Drug	Basifungin	PRKG1 ABCB1 ABCB4	4.52e-05	18	89	3	CID000072050
Drug	dithiol	ALOX12 ALOX5	4.52e-05	3	89	2	ctd:C004848
Drug	Technetium Tc 99m Sestamibi	ABCB1 ABCB4	4.52e-05	3	89	2	ctd:D017256
Drug	N-hydroxy-4-acetylaminobiphenyl	NAT1 NAT2	4.52e-05	3	89	2	ctd:C001365
Drug	3,5-dimethylaniline	NAT1 NAT2	4.52e-05	3	89	2	CID000007949
Drug	4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine	ALOX12 ALOX5	4.52e-05	3	89	2	ctd:D015772
Disease	hereditary spastic paraplegia 76 (implicated_via_orthology)	CAPN8 CAPN2 CAPN3	2.64e-07	5	89	3	DOID:0110821 (implicated_via_orthology)
Disease	occupational dermatitis (is_implicated_in)	NAT1 NAT2	9.00e-06	2	89	2	DOID:4404 (is_implicated_in)
Disease	hepatic encephalopathy (biomarker_via_orthology)	INSR G6PD ABCB1	1.18e-05	15	89	3	DOID:13413 (biomarker_via_orthology)
Disease	intellectual disability (implicated_via_orthology)	CAPN8 ZC3H14 CAPN2 CAPN3	7.98e-05	75	89	4	DOID:1059 (implicated_via_orthology)
Disease	Neurotoxicity Syndromes	ADRA1B ST8SIA1 ABCB1	9.16e-05	29	89	3	C0235032
Disease	Encephalopathy, Toxic	ADRA1B ST8SIA1 ABCB1	9.16e-05	29	89	3	C0149504
Disease	Toxic Encephalitis	ADRA1B ST8SIA1 ABCB1	9.16e-05	29	89	3	C0154659
Disease	diabetes mellitus (is_implicated_in)	NAT2 INSR G6PD	9.16e-05	29	89	3	DOID:9351 (is_implicated_in)
Disease	Parkinson Disease	TCL1B IGF2R INSR ABCB1	1.30e-04	85	89	4	C0030567
Disease	allergic contact dermatitis (is_implicated_in)	NAT1 NAT2	1.34e-04	6	89	2	DOID:3042 (is_implicated_in)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CAPN8 CAPN2 CAPN3	1.76e-04	36	89	3	DOID:11723 (implicated_via_orthology)
Disease	Industrial Dermatosis	NAT1 NAT2	2.49e-04	8	89	2	C0086457
Disease	Dermatitis, Occupational	NAT1 NAT2	2.49e-04	8	89	2	C0028796
Disease	pulmonary tuberculosis (is_implicated_in)	NAT2 ALOX5 ABCB1	2.80e-04	42	89	3	DOID:2957 (is_implicated_in)
Disease	hereditary spastic paraplegia (implicated_via_orthology)	CAPN8 CAPN2 CAPN3	3.00e-04	43	89	3	DOID:2476 (implicated_via_orthology)
Disease	gallbladder neoplasm	ABCB1 ABCB4	3.19e-04	9	89	2	EFO_0004606
Disease	cystic fibrosis (implicated_via_orthology)	ABCB1 ABCB4	3.19e-04	9	89	2	DOID:1485 (implicated_via_orthology)
Disease	5-acetylamino-6-formylamino-3-methyluracil measurement	NAT1 NAT2	3.19e-04	9	89	2	EFO_0800950
Disease	hepatocellular carcinoma (biomarker_via_orthology)	CAPN3 INSR G6PD ABCB1	3.26e-04	108	89	4	DOID:684 (biomarker_via_orthology)
Disease	end stage renal disease (biomarker_via_orthology)	NAT1 NAT2 ABCB1	3.91e-04	47	89	3	DOID:783 (biomarker_via_orthology)
Disease	cholestasis (biomarker_via_orthology)	G6PD ABCB1 ABCB4	4.42e-04	49	89	3	DOID:13580 (biomarker_via_orthology)
Disease	amino acid metabolic disorder (is_implicated_in)	ASL PCCA	4.86e-04	11	89	2	DOID:9252 (is_implicated_in)
Disease	peptidyl-glycine alpha-amidating monooxygenase measurement	MYCBP2 GIN1	4.86e-04	11	89	2	EFO_0801871
Disease	5-acetylamino-6-amino-3-methyluracil measurement	NAT1 NAT2	4.86e-04	11	89	2	EFO_0800951
Disease	Enzymopathy	PRKG1 G6PD	4.86e-04	11	89	2	C0520572
Disease	obesity (implicated_via_orthology)	CAPN8 FLII CAPN2 CAPN3 LPIN2	4.95e-04	215	89	5	DOID:9970 (implicated_via_orthology)
Disease	N-acetylputrescine measurement	NAT1 NAT2	5.82e-04	12	89	2	EFO_0800127
Disease	temporal pole volume measurement	GPR158 PTPRU	5.82e-04	12	89	2	EFO_0010334
Disease	renal cell carcinoma (is_marker_for)	INSR NNMT ALOX12 ABCB1	6.20e-04	128	89	4	DOID:4450 (is_marker_for)
Disease	gamma-glutamylleucine measurement	FARS2 PRKG1	6.87e-04	13	89	2	EFO_0021140
Disease	obsolete_red blood cell distribution width	GPR158 FARS2 INSR LPIN2 DKC1 STK39 ITGAD G6PD ATP2B3 ABCB1 SORD ABCB4	7.18e-04	1347	89	12	EFO_0005192
Disease	diabetic neuropathy (implicated_via_orthology)	INSR SORD	8.00e-04	14	89	2	DOID:9743 (implicated_via_orthology)
Disease	Bladder Neoplasm	NAT1 NAT2 CALHM1 GSTO2	8.67e-04	140	89	4	C0005695
Disease	Malignant neoplasm of urinary bladder	NAT1 NAT2 CALHM1 GSTO2	8.91e-04	141	89	4	C0005684
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	INSR G6PD ABCB1	1.01e-03	65	89	3	DOID:0080208 (biomarker_via_orthology)
Disease	amino acid measurement	NAT2 SLC6A12 IMPG1 MYO1E STK39 PRKG1 ST8SIA1 ALOX15	1.03e-03	678	89	8	EFO_0005134
Disease	Intrahepatic cholestasis of pregnancy	ABCB1 ABCB4	1.05e-03	16	89	2	EFO_0009048
Disease	photoreceptor cell layer thickness measurement	GDPD4 IMPG1 STK39 WDR72	1.07e-03	148	89	4	EFO_0803370
Disease	Malignant neoplasm of breast	NAT2 TCL1B ASL TLL1 CST4 TENM1 SIX4 MAGEE1 PLOD1 ABCB1	1.47e-03	1074	89	10	C0006142
Disease	Congenital hernia of foramen of Morgagni	IGF2R INSR	1.49e-03	19	89	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF2R INSR	1.49e-03	19	89	2	C0265700
Disease	Congenital diaphragmatic hernia	IGF2R INSR	1.82e-03	21	89	2	C0235833
Disease	Lewy Body Disease	IGF2R INSR	2.00e-03	22	89	2	C0752347
Disease	Allodynia	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C0458247
Disease	Mechanical Allodynia	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C2936719
Disease	Hyperalgesia, Secondary	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C0751212
Disease	Hyperalgesia, Primary	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C0751211
Disease	Hyperalgesia, Thermal	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C0751214
Disease	Tactile Allodynia	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C0751213
Disease	Drug toxicity	NAT1 NAT2 ABCB1	2.12e-03	84	89	3	C0013221
Disease	Adverse reaction to drug	NAT1 NAT2 ABCB1	2.12e-03	84	89	3	C0041755
Disease	Hyperalgesia	INSR ALOX12 ALOX5	2.12e-03	84	89	3	C0020429
Disease	malaria (is_implicated_in)	G6PD ABCB1	2.38e-03	24	89	2	DOID:12365 (is_implicated_in)
Disease	diet measurement, bilirubin measurement	NAT1 PTPRT	2.79e-03	26	89	2	EFO_0004570, EFO_0008111

Protein segments in the cluster

Peptide	Gene	Start	Entry
VPCVFRLTEENGFWY	NAT1	146	P18440
CLYPGFVDVKEADWI	ALKBH3	91	Q96Q83
EVLGYWVLGRIFCDI	ADRA1B	106	P35368
CPEIYDGDWLLAREV	CALHM1	161	Q8IU99
DGIEWRNKYICVEEP	TENT2	421	Q6PIY7
YGEWVEVVIDDRLPT	CAPN8	146	A6NHC0
EVDIKGVFRYCNTWP	SORD	291	Q00796
LGEERYTPAIDVWSC	CDK13	886	Q14004
VVEGRTWLAECTPVY	ATP2B3	396	Q16720
EVAQGWCREKDIPYF	RAB7B	136	Q96AH8
VLYVENERWDGVPFI	G6PD	341	P11413
GRYFWSIPEEEFLCE	LRFN5	271	Q96NI6
TEWPYFVVGVFCAII	ABCB1	706	P08183
VEWEADFEPYVVVRR	LARGE1	651	O95461
FLCRYWVPVEYEEEE	FLII	936	Q13045
IEGYCTPEEVIWEAL	MAGEA10	236	P43363
PGWVEYFIAALRGCE	MAVS	66	Q7Z434
RPVTDCKPVEYEFFW	MAGEE1	641	Q9HCI5
EFCRTYVLPADVDPW	HSPB2	116	Q16082
FDIGEVCPWEVYDLT	GPR158	1001	Q5T848
RIPDTGEYQDWVSIC	IMPG1	116	Q17R60
WTFCGTPEYVAPEII	PRKG1	516	Q13976
ISPLFSGDVICVWDY	ASL	416	P04424
VYGWEPERCFDVVLV	KATNB1	256	Q9BVA0
VEFPIGCSWRGVEYR	PLXNA3	276	P51805
DPEAVIYVCSVAAEW	OGDHL	466	Q9ULD0
EPEAFDWSPVVTYVC	NNMT	101	P40261
WFERLDVYGILDCVS	GSTO2	181	Q9H4Y5
EVRFPCYRWVEGNGV	ALOX15	91	P16050
VQPWCYVAETEEGIY	KREMEN2	96	Q8NCW0
WPVAFYVACLEREVR	GDPD4	121	Q6W3E5
RYFWAVGEEEFVCEP	LRFN3	281	Q9BTN0
FPCSVYVPDEWEVSR	INSR	1006	P06213
EVAFPCYRWVQGEDI	ALOX12	91	P18054
CYRWVQGEDILSLPE	ALOX12	96	P18054
INGWAVECRVYAEDP	PCCA	391	P05165
YWFPIFTEVACDELV	PLOD1	556	Q02809
TEWPYFVVGTVCAIA	ABCB4	706	P21439
EVGRVKCVRYWPDDT	PTPRT	991	O14522
VEVGRVKCSRYWPED	PTPRU	991	Q92729
FSPVEVAKAVYRCWE	ITGAD	626	Q13349
VIRPGCELLVWYGDE	PRDM9	346	Q9NQV7
LFTVCDERWGGEIYP	HCRTR2	206	O43614
VCVEYEREETVVSPW	CPLANE1	3106	Q9H799
WPHVFRVCEYVGTLE	ARFGEF3	1011	Q5TH69
EVDIGSDLYWPCVAT	CNTN1	341	Q12860
VVRGCWVLYEEPEFR	CRYBG2	1021	Q8N1P7
YRIESPELDCEEGWT	IFIT2	131	P09913
VPCIFCLTEERGIWY	NAT2	146	P11245
IIGEIVISCYWLFEI	LINC00470	66	Q9BZP3
RYEVVTELGPEEVRW	DDHD1	156	Q8NEL9
YGEWVEVVVDDRLPT	CAPN2	146	P17655
GEWVDVVIDDCLPTY	CAPN3	171	P20807
QLCSFEIYEVPWEDR	CST4	116	P01036
EYDPERRLGIFWVSC	DKC1	206	O60832
EPCVDGWVYDRSVFT	SLC22A11	111	Q9NSA0
QVEYEILFPGCVLRW	SEC14L2	291	O76054
QVEYEILFPGCVLRW	SEC14L3	291	Q9UDX4
EYVFIWRTVEACPVV	IGF2R	1206	P11717
CDIAGYYPLDVVVTW	TAPBPL	321	Q9BX59
YPGQVDCEWLLVSER	TLL1	911	O43897
EWVCVIDILIFYGTF	TMEM150A	211	Q86TG1
IEFPCYRWITGDVEV	ALOX5	96	P09917
GRFQSEWVGPCVIDY	GIN1	381	Q9NXP7
EWVGPCVIDYITESG	GIN1	386	Q9NXP7
LFEVVCISWVYGADR	SLC6A12	466	P48065
LPRTIWDGEETVYCF	SIX4	216	Q9UIU6
LCEEVAIYGFWPFSV	ST8SIA1	286	Q92185
EYETCPDFILWEQRT	TENM1	1106	Q9UKZ4
VGFEYETCPSLILWE	TENM2	1146	Q9NT68
FGVCLDPVYDVIWRF	MYCBP2	1126	O75592
IVDEDPYAIQIISWC	STXBP5	496	Q5T5C0
IWQTEPFLYIDTVCD	TMEM176B	151	Q3YBM2
EEWPLVDDCTGVTGY	PIK3CG	321	P48736
CTWYLVAFPPEVVTD	TAS1R3	696	Q7RTX0
SPRGEWIYCVGEDFV	SMU1	451	Q2TAY7
ELVYEIEGCEVIWAI	PYROXD1	161	Q8WU10
IVYGTLEEVWDCVKP	STARD5	56	Q9NSY2
FLIVGCADDSVYIWE	WDR72	571	Q3MJ13
IYWVSVCFPVCVEVP	SCN3B	16	Q9NY72
PGIYEDEEGRTWVTV	TCL1B	21	O95988
IEYLVDGSWCPIRAE	PIAS4	396	Q8N2W9
DVERSRFPYCVVWTP	TMEM222	46	Q9H0R3
WPICRDAYELQEVIG	STK39	56	Q9UEW8
GDELEIRWVDCYFPF	FARS2	256	O95363
SSWVYETGRLCEPEV	ZC3H14	251	Q6PJT7
VAVYFCREEWGCLRP	ZNF764	31	Q96H86
PFLTYVEGVCVVWFT	KCNC3	346	Q14003
EFSSFCYWRDPIPEV	LPIN2	876	Q92539
EEYVQEGIRWTPIEY	MYO1E	426	Q12965
YLVEYCLEGSEEWVP	MYBPC2	771	Q14324