Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of small GTPase mediated signal transduction	RELN GPR17 LPAR4 CSF1 AKAP13 NOTCH1	3.58e-05	92	138	6	GO:0051057
GeneOntologyBiologicalProcess	negative regulation of cell proliferation involved in heart valve morphogenesis	BMPR2 NOTCH1	4.44e-05	2	138	2	GO:0003252
GeneOntologyBiologicalProcess	cell morphogenesis	VLDLR RELN ANK3 NRDC APC LAMA2 LAMC1 ZFPM1 ARHGAP35 DSCAML1 BRWD3 BTBD3 MYO3A BMPR2 HMCN2 WASF2 PKHD1 MACF1 DNMBP UNC13A NOTCH1	4.49e-05	1194	138	21	GO:0000902
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	PDE4B NRDC ARID4A ABCA12 APC LAMA2 IL20RB LAMC1 TNFRSF11A ZFPM1 KMT2E ITGAM LEPR CSF1 PLCL2 RP1 FH MUC2 NOTCH1	6.77e-05	1043	138	19	GO:0048871
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	VLDLR RELN ANK3 NRDC APC LAMA2 LAMC1 ARHGAP35 DSCAML1 BTBD3 BMPR2 HMCN2 WASF2 MACF1 UNC13A NOTCH1	1.20e-04	819	138	16	GO:0120039
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	VLDLR RELN NRDC APC KAT2A ARHGAP35 MYO3A KAT2B BMPR2 WASF2 MACF1 RP1	1.24e-04	494	138	12	GO:0031346
GeneOntologyBiologicalProcess	mitral valve morphogenesis	ZFPM1 BMPR2 NOTCH1	1.26e-04	15	138	3	GO:0003183
GeneOntologyBiologicalProcess	axon guidance	RELN ANK3 LAMA2 LAMC1 ARHGAP35 DSCAML1 BMPR2 HMCN2 NOTCH1	1.31e-04	285	138	9	GO:0007411
GeneOntologyBiologicalProcess	cell projection morphogenesis	VLDLR RELN ANK3 NRDC APC LAMA2 LAMC1 ARHGAP35 DSCAML1 BTBD3 BMPR2 HMCN2 WASF2 MACF1 UNC13A NOTCH1	1.32e-04	826	138	16	GO:0048858
GeneOntologyBiologicalProcess	regulation of cell proliferation involved in heart valve morphogenesis	BMPR2 NOTCH1	1.33e-04	3	138	2	GO:0003250
GeneOntologyBiologicalProcess	cell proliferation involved in heart valve morphogenesis	BMPR2 NOTCH1	1.33e-04	3	138	2	GO:0003249
GeneOntologyBiologicalProcess	neuron projection guidance	RELN ANK3 LAMA2 LAMC1 ARHGAP35 DSCAML1 BMPR2 HMCN2 NOTCH1	1.35e-04	286	138	9	GO:0097485
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	VLDLR RELN ANK3 NRDC APC LAMA2 LAMC1 ARHGAP35 DSCAML1 BTBD3 MYO3A BMPR2 HMCN2 MACF1 NOTCH1	1.49e-04	748	138	15	GO:0048667
GeneOntologyBiologicalProcess	mitral valve development	ZFPM1 BMPR2 NOTCH1	1.54e-04	16	138	3	GO:0003174
GeneOntologyBiologicalProcess	regulation of postsynaptic neurotransmitter receptor activity	DLGAP2 DLGAP1 NOTCH1	1.86e-04	17	138	3	GO:0098962
GeneOntologyBiologicalProcess	negative regulation of cell proliferation involved in heart morphogenesis	BMPR2 NOTCH1	2.64e-04	4	138	2	GO:2000137
GeneOntologyBiologicalProcess	disaccharide catabolic process	MGAM SI	2.64e-04	4	138	2	GO:0046352
GeneOntologyBiologicalProcess	cell proliferation involved in heart valve development	BMPR2 NOTCH1	2.64e-04	4	138	2	GO:2000793
GeneOntologyBiologicalProcess	neuron projection morphogenesis	VLDLR RELN ANK3 NRDC APC LAMA2 LAMC1 ARHGAP35 DSCAML1 BTBD3 BMPR2 HMCN2 MACF1 UNC13A NOTCH1	3.15e-04	802	138	15	GO:0048812
GeneOntologyBiologicalProcess	regulation of delayed rectifier potassium channel activity	AKAP6 ANK3 KCNRG	3.57e-04	21	138	3	GO:1902259
GeneOntologyBiologicalProcess	temperature homeostasis	NRDC APC TNFRSF11A LEPR PLCL2 FH NOTCH1	3.57e-04	196	138	7	GO:0001659
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	VLDLR NOP53 APC LAMP2 ICE1 CEP192 KAT2A ARHGAP35 CARD8 MYO3A KAT2B WASF2 ULK4 MACF1 ADGRE5 RP1 TASOR UNC13A NOTCH1	3.64e-04	1189	138	19	GO:0044087
GeneOntologyBiologicalProcess	homeostasis of number of cells within a tissue	IL20RB CSF1 FH NOTCH1	3.76e-04	51	138	4	GO:0048873
GeneOntologyBiologicalProcess	regulation of centrosome duplication	CEP192 KAT2A KAT2B PKHD1	4.05e-04	52	138	4	GO:0010824
GeneOntologyBiologicalProcess	anatomical structure homeostasis	LAMA2 IL20RB LAMC1 TNFRSF11A CSF1 RP1 FH MUC2 NOTCH1	4.23e-04	334	138	9	GO:0060249
GeneOntologyBiologicalProcess	tissue homeostasis	LAMA2 IL20RB LAMC1 TNFRSF11A CSF1 RP1 FH MUC2 NOTCH1	4.23e-04	334	138	9	GO:0001894
GeneOntologyBiologicalProcess	axonogenesis	RELN ANK3 NRDC APC LAMA2 LAMC1 ARHGAP35 DSCAML1 BMPR2 HMCN2 MACF1 NOTCH1	4.29e-04	566	138	12	GO:0007409
GeneOntologyBiologicalProcess	mitral valve formation	ZFPM1 NOTCH1	4.39e-04	5	138	2	GO:0003192
GeneOntologyBiologicalProcess	regulation of mast cell differentiation	ZFPM1 ITGAM	4.39e-04	5	138	2	GO:0060375
Domain	EGF-like_dom	VLDLR FRAS1 RELN LAMA2 LAMC1 LRP1B ADGRL4 EYS MALRD1 HMCN2 ADGRE5 C8A NAGPA NOTCH1	3.21e-09	249	134	14	IPR000742
Domain	EGF	VLDLR FRAS1 RELN LAMA2 LAMC1 LRP1B ADGRL4 EYS MALRD1 ADGRE5 NAGPA NOTCH1	1.30e-07	235	134	12	SM00181
Domain	Growth_fac_rcpt_	VLDLR FRAS1 ERBB3 LAMC1 LRP1B EYS HMCN2 ADGRE5 C8A NOTCH1	1.86e-07	156	134	10	IPR009030
Domain	EGF-like_CS	VLDLR RELN LAMA2 LAMC1 LRP1B ADGRL4 EYS MALRD1 HMCN2 C8A NAGPA NOTCH1	4.01e-07	261	134	12	IPR013032
Domain	EGF_2	VLDLR RELN LAMA2 LAMC1 LRP1B ADGRL4 EYS MALRD1 HMCN2 C8A NAGPA NOTCH1	4.72e-07	265	134	12	PS01186
Domain	EGF_3	VLDLR RELN LRP1B ADGRL4 EYS MALRD1 HMCN2 ADGRE5 C8A NAGPA NOTCH1	1.05e-06	235	134	11	PS50026
Domain	EGF_1	VLDLR RELN LAMA2 LAMC1 LRP1B EYS MALRD1 HMCN2 C8A NAGPA NOTCH1	2.32e-06	255	134	11	PS00022
Domain	EGF_Ca-bd_CS	VLDLR LRP1B ADGRL4 EYS HMCN2 ADGRE5 NOTCH1	6.28e-06	97	134	7	IPR018097
Domain	PbH1	PKHD1L1 FBXO10 PKHD1	7.11e-06	6	134	3	SM00710
Domain	PbH1	PKHD1L1 FBXO10 PKHD1	7.11e-06	6	134	3	IPR006626
Domain	EGF_CA	VLDLR LRP1B ADGRL4 EYS HMCN2 ADGRE5 NOTCH1	7.19e-06	99	134	7	PS01187
Domain	ASX_HYDROXYL	VLDLR LRP1B ADGRL4 EYS HMCN2 ADGRE5 NOTCH1	7.69e-06	100	134	7	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	VLDLR LRP1B ADGRL4 EYS HMCN2 ADGRE5 NOTCH1	1.13e-05	106	134	7	IPR000152
Domain	Pectin_lyase_fold/virulence	PKHD1L1 FBXO10 PKHD1	1.97e-05	8	134	3	IPR011050
Domain	EGF_CA	VLDLR LRP1B ADGRL4 EYS HMCN2 ADGRE5 NOTCH1	2.82e-05	122	134	7	SM00179
Domain	EGF-like_Ca-bd_dom	VLDLR LRP1B ADGRL4 EYS HMCN2 ADGRE5 NOTCH1	3.13e-05	124	134	7	IPR001881
Domain	EGF_CA	VLDLR LRP1B ADGRL4 HMCN2 ADGRE5 NOTCH1	3.58e-05	86	134	6	PF07645
Domain	Hist_acetylase_PCAF	KAT2A KAT2B	5.11e-05	2	134	2	IPR016376
Domain	PCAF_N	KAT2A KAT2B	5.11e-05	2	134	2	IPR009464
Domain	PCAF_N	KAT2A KAT2B	5.11e-05	2	134	2	PF06466
Domain	BROMODOMAIN_1	ASH1L KAT2A BRWD3 KAT2B	1.39e-04	37	134	4	PS00633
Domain	Bromodomain	ASH1L KAT2A BRWD3 KAT2B	1.55e-04	38	134	4	PF00439
Domain	LDLR_class-A_CS	VLDLR LRP1B MALRD1 C8A	1.89e-04	40	134	4	IPR023415
Domain	BROMODOMAIN_2	ASH1L KAT2A BRWD3 KAT2B	2.09e-04	41	134	4	PS50014
Domain	Bromodomain	ASH1L KAT2A BRWD3 KAT2B	2.30e-04	42	134	4	IPR001487
Domain	BROMO	ASH1L KAT2A BRWD3 KAT2B	2.30e-04	42	134	4	SM00297
Domain	-	ASH1L KAT2A BRWD3 KAT2B	2.30e-04	42	134	4	1.20.920.10
Domain	EGF	VLDLR LRP1B EYS MALRD1 NAGPA NOTCH1	2.97e-04	126	134	6	PF00008
Domain	Ldl_recept_a	VLDLR LRP1B MALRD1 C8A	3.00e-04	45	134	4	PF00057
Domain	G8_domain	PKHD1L1 PKHD1	3.04e-04	4	134	2	IPR019316
Domain	Glyco_hydro_31_CS	MGAM SI	3.04e-04	4	134	2	IPR030459
Domain	G8	PKHD1L1 PKHD1	3.04e-04	4	134	2	PS51484
Domain	Gal_mutarotase_N	MGAM SI	3.04e-04	4	134	2	IPR031727
Domain	G8	PKHD1L1 PKHD1	3.04e-04	4	134	2	SM01225
Domain	G8	PKHD1L1 PKHD1	3.04e-04	4	134	2	PF10162
Domain	NtCtMGAM_N	MGAM SI	3.04e-04	4	134	2	PF16863
Domain	-	VLDLR LRP1B MALRD1 C8A	3.27e-04	46	134	4	4.10.400.10
Domain	LDLRA_1	VLDLR LRP1B MALRD1 C8A	3.86e-04	48	134	4	PS01209
Domain	LDrepeatLR_classA_rpt	VLDLR LRP1B MALRD1 C8A	4.18e-04	49	134	4	IPR002172
Domain	LDLa	VLDLR LRP1B MALRD1 C8A	4.18e-04	49	134	4	SM00192
Domain	LDLRA_2	VLDLR LRP1B MALRD1 C8A	4.18e-04	49	134	4	PS50068
Domain	GLYCOSYL_HYDROL_F31_2	MGAM SI	5.04e-04	5	134	2	PS00707
Domain	SAPAP	DLGAP2 DLGAP1	5.04e-04	5	134	2	IPR005026
Domain	GKAP	DLGAP2 DLGAP1	5.04e-04	5	134	2	PF03359
Domain	Pectin_lyas_fold	FBXO10 PKHD1	7.52e-04	6	134	2	IPR012334
Domain	SPOC_C	PHF3 SPOCD1	7.52e-04	6	134	2	IPR012921
Domain	Glyco_hydro_31_AS	MGAM SI	7.52e-04	6	134	2	IPR030458
Domain	-	FBXO10 PKHD1	7.52e-04	6	134	2	2.160.20.10
Domain	SPOC	PHF3 SPOCD1	7.52e-04	6	134	2	PF07744
Domain	EGF_extracell	RELN LRP1B NAGPA NOTCH1	9.05e-04	60	134	4	IPR013111
Domain	EGF_2	RELN LRP1B NAGPA NOTCH1	9.05e-04	60	134	4	PF07974
Domain	Glyco_hydro_31	MGAM SI	1.05e-03	7	134	2	IPR000322
Domain	TFS2M	PHF3 SPOCD1	1.05e-03	7	134	2	SM00510
Domain	Glyco_hydro_31	MGAM SI	1.05e-03	7	134	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM SI	1.05e-03	7	134	2	PS00129
Domain	TFIIS_M	PHF3 SPOCD1	1.05e-03	7	134	2	PF07500
Domain	TFIIS_cen_dom	PHF3 SPOCD1	1.39e-03	8	134	2	IPR003618
Domain	P_TREFOIL_1	MGAM SI	1.39e-03	8	134	2	PS00025
Domain	-	PHF3 SPOCD1	1.39e-03	8	134	2	1.10.472.30
Domain	Trefoil	MGAM SI	1.39e-03	8	134	2	PF00088
Domain	LAMININ_IVA	LAMA2 LAMC1	1.39e-03	8	134	2	PS51115
Domain	Laminin_B	LAMA2 LAMC1	1.39e-03	8	134	2	PF00052
Domain	TFIIS_CENTRAL	PHF3 SPOCD1	1.39e-03	8	134	2	PS51321
Domain	LamB	LAMA2 LAMC1	1.39e-03	8	134	2	SM00281
Domain	P_trefoil_CS	MGAM SI	1.39e-03	8	134	2	IPR017957
Domain	Laminin_IV	LAMA2 LAMC1	1.39e-03	8	134	2	IPR000034
Domain	P_TREFOIL_2	MGAM SI	1.78e-03	9	134	2	PS51448
Domain	PD	MGAM SI	1.78e-03	9	134	2	SM00018
Domain	-	MGAM SI	2.69e-03	11	134	2	4.10.110.10
Domain	Laminin_G_1	LAMA2 EYS	2.69e-03	11	134	2	PF00054
Domain	P_trefoil_dom	MGAM SI	3.22e-03	12	134	2	IPR000519
Domain	C-type_lectin_CS	SFTPA2 SFTPA1 CLEC10A	3.61e-03	43	134	3	IPR018378
Domain	Ldl_recept_b	VLDLR LRP1B	4.39e-03	14	134	2	PF00058
Domain	LDLRB	VLDLR LRP1B	4.39e-03	14	134	2	PS51120
Domain	LY	VLDLR LRP1B	5.05e-03	15	134	2	SM00135
Domain	LDLR_classB_rpt	VLDLR LRP1B	5.05e-03	15	134	2	IPR000033
Domain	Laminin_N	LAMA2 LAMC1	5.74e-03	16	134	2	IPR008211
Domain	LamNT	LAMA2 LAMC1	5.74e-03	16	134	2	SM00136
Domain	LAMININ_NTER	LAMA2 LAMC1	5.74e-03	16	134	2	PS51117
Domain	Laminin_N	LAMA2 LAMC1	5.74e-03	16	134	2	PF00055
Domain	Gal_mutarotase_SF_dom	MGAM SI	6.48e-03	17	134	2	IPR011013
Pathway	WP_GASTRIC_CANCER_NETWORK_1	CENPF APC CEP192 LIN9 NOTCH1	1.27e-06	28	98	5	M39347
Pathway	WP_CLOCKCONTROLLED_AUTOPHAGY_IN_BONE_METABOLISM	ATG16L1 LAMP2 TNFRSF11A BMPR2 CSF1 NOTCH1	1.92e-05	80	98	6	M45523
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	KAT2A KAT2B NOTCH1	3.77e-05	10	98	3	MM15535
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	KAT2A KAT2B NOTCH1	1.12e-04	14	98	3	M27808
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	KAT2A KAT2B NOTCH1	1.71e-04	16	98	3	M27121
Pubmed	Surfactant protein A modulates cell surface expression of CR3 on alveolar macrophages and enhances CR3-mediated phagocytosis.	ITGAM SFTPA2 SFTPA1	6.38e-08	3	140	3	19155216
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 APC LAMC1 CEP192 ITPRID2 CARD8 GAB2 BMPR2 PHF3 STARD9 PI4KB EXO1 MACF1 AKAP13 DNMBP DOP1A	4.25e-07	861	140	16	36931259
Pubmed	Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5.	KAT2A KAT2B NOTCH1	6.35e-07	5	140	3	10747963
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FRAS1 LAMA2 LAMC1 GRIA2	7.37e-07	18	140	4	14730302
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CACHD1 DSCAML1 BTBD3 PLCL2 MACF1 TASOR UNC13A	1.03e-06	130	140	7	12421765
Pubmed	Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.	VLDLR RELN NOTCH1	1.27e-06	6	140	3	18957219
Pubmed	DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.	DLGAP2 DLGAP1 APC	2.21e-06	7	140	3	9286858
Pubmed	ErbB4 regulates the timely progression of late fetal lung development.	ITGAM SFTPA2 SFTPA1	2.21e-06	7	140	3	20303366
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ERBB3 ANK3 NOP53 ICE1 RLF CFAP20DC HMCN2 PHF3 MACF1 AKAP13	2.23e-06	361	140	10	26167880
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRMT9B PRUNE2 ANK3 KIZ ASH1L CEP192 ARHGAP35 ARMC2 BRWD3 RLF ZNF462 PKNOX2 CFAP20DC BMPR2 MACF1 AKAP13 LRBA ICA1L GPA33 DOP1A	2.32e-06	1489	140	20	28611215
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PPP4R1 FRAS1 ERBB3 NRDC APC DGKA SRPK1 WASF2 MID1 AKAP13 TASOR TOP3A SLC27A4	2.47e-06	650	140	13	38777146
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	VLDLR ERBB3 TRPC1 LRP1B LEPR NOTCH1	3.54e-06	101	140	6	23382219
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 PRUNE2 ARHGAP35 BIRC6 DSCAML1 ZNF462 PHF3 MACF1	3.89e-06	225	140	8	12168954
Pubmed	The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers.	VLDLR MGAM RLF	5.27e-06	9	140	3	25857663
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FRAS1 LAMA2 LAMC1 SFTPA2 HMCN2 SFTPA1 MUC2	5.45e-06	167	140	7	22159717
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	DLGAP1 ERBB3 TRA PKHD1L1 BTBD3 PKNOX2 DDIAS MYO3A MALRD1 CSF1 NALF1 ADAMTS20 DDX60L UNC13A	5.68e-06	814	140	14	23251661
Pubmed	EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.	APC KAT2B MACF1	7.50e-06	10	140	3	23001180
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CENPF APC LAMC1 ICE1 BIRC6 LIN9 RLF ZNF462 LRBA TASOR	8.09e-06	418	140	10	34709266
Pubmed	Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.	KAT2A LEPR KAT2B	1.03e-05	11	140	3	24051374
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	DOCK4 DPYS LAMA2 LAMC1 TP53BP1	1.03e-05	71	140	5	33541421
Pubmed	l7Rn6 encodes a novel protein required for clara cell function in mouse lung development.	LAMP2 SFTPA2 SFTPA1	1.37e-05	12	140	3	16157679
Pubmed	Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia.	KAT2B SFTPA2 SFTPA1	1.37e-05	12	140	3	21402781
Pubmed	Maternal surfactant protein A influences the immunoprotective properties of milk in a murine model.	SFTPA2 SFTPA1	1.61e-05	2	140	2	24858142
Pubmed	Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.	SFTPA2 SFTPA1	1.61e-05	2	140	2	24954098
Pubmed	Surfactant protein A modulates neuroinflammation in adult mice upon pulmonary infection.	SFTPA2 SFTPA1	1.61e-05	2	140	2	38964703
Pubmed	Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.	SFTPA2 SFTPA1	1.61e-05	2	140	2	22219327
Pubmed	Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.	SFTPA2 SFTPA1	1.61e-05	2	140	2	15890661
Pubmed	Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.	SFTPA2 SFTPA1	1.61e-05	2	140	2	15385504
Pubmed	Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.	SFTPA2 SFTPA1	1.61e-05	2	140	2	23038062
Pubmed	Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	17307210
Pubmed	Surfactant protein A modulates induction of regulatory T cells via TGF-β.	SFTPA2 SFTPA1	1.61e-05	2	140	2	22474025
Pubmed	Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	38553537
Pubmed	Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity.	KAT2A KAT2B	1.61e-05	2	140	2	34270849
Pubmed	Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum.	SFTPA2 SFTPA1	1.61e-05	2	140	2	33510368
Pubmed	Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.	SFTPA2 SFTPA1	1.61e-05	2	140	2	11342662
Pubmed	Lung development in the mouse embryo.	SFTPA2 SFTPA1	1.61e-05	2	140	2	2050021
Pubmed	Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation.	KAT2A DNMBP	1.61e-05	2	140	2	31878840
Pubmed	Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.	SFTPA2 SFTPA1	1.61e-05	2	140	2	12922979
Pubmed	The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer.	PDE4B APC	1.61e-05	2	140	2	30188895
Pubmed	Novel role for surfactant protein A in gastrointestinal graft-versus-host disease.	SFTPA2 SFTPA1	1.61e-05	2	140	2	22508928
Pubmed	Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.	NRDC APC	1.61e-05	2	140	2	29669932
Pubmed	Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4.	SFTPA2 SFTPA1	1.61e-05	2	140	2	35444643
Pubmed	Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.	SFTPA2 SFTPA1	1.61e-05	2	140	2	11867335
Pubmed	SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	19494306
Pubmed	Characterization of a second human pulmonary surfactant-associated protein SP-A gene.	SFTPA2 SFTPA1	1.61e-05	2	140	2	1372511
Pubmed	The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.	SFTPA2 SFTPA1	1.61e-05	2	140	2	21205009
Pubmed	Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.	SFTPA2 SFTPA1	1.61e-05	2	140	2	24312669
Pubmed	Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants.	SFTPA2 SFTPA1	1.61e-05	2	140	2	17580966
Pubmed	Winnie-APCMin/+ Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation.	APC MUC2	1.61e-05	2	140	2	32340123
Pubmed	Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.	APC MUC2	1.61e-05	2	140	2	18794118
Pubmed	TRAC variants associate with IgA nephropathy.	TRA TRAC	1.61e-05	2	140	2	19470682
Pubmed	Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1-Mediated Metabolic and Epigenetic Changes.	BMPR2 NOTCH1	1.61e-05	2	140	2	30582451
Pubmed	Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.	SFTPA2 SFTPA1	1.61e-05	2	140	2	20448439
Pubmed	Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A.	SFTPA2 SFTPA1	1.61e-05	2	140	2	24080545
Pubmed	Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.	SFTPA2 SFTPA1	1.61e-05	2	140	2	1443158
Pubmed	Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.	SFTPA2 SFTPA1	1.61e-05	2	140	2	27835691
Pubmed	Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.	MGAM SI	1.61e-05	2	140	2	27480812
Pubmed	Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.	SFTPA2 SFTPA1	1.61e-05	2	140	2	34484180
Pubmed	Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.	APC LEPR	1.61e-05	2	140	2	18725892
Pubmed	Surfactant protein-A reduces translocation of mediators from the lung into the circulation.	SFTPA2 SFTPA1	1.61e-05	2	140	2	20715984
Pubmed	PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.	APC MUC2	1.61e-05	2	140	2	19232344
Pubmed	Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.	SFTPA2 SFTPA1	1.61e-05	2	140	2	18159253
Pubmed	Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries.	SFTPA2 SFTPA1	1.61e-05	2	140	2	37256132
Pubmed	Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinates.	LEPR NOTCH1	1.61e-05	2	140	2	30951821
Pubmed	Surfactant Protein A, a Novel Regulator for Smooth Muscle Phenotypic Modulation and Vascular Remodeling-Brief Report.	SFTPA2 SFTPA1	1.61e-05	2	140	2	33267655
Pubmed	Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.	SFTPA2 SFTPA1	1.61e-05	2	140	2	10781424
Pubmed	Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.	RELN NOTCH1	1.61e-05	2	140	2	26635527
Pubmed	SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved.	SFTPA2 SFTPA1	1.61e-05	2	140	2	29202868
Pubmed	Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene.	SFTPA2 SFTPA1	1.61e-05	2	140	2	20693318
Pubmed	Transcriptional coactivator p300/CBP-associated factor and p300/CBP-associated factor type B are required for normal estrogen response of the mouse uterus.	KAT2A KAT2B	1.61e-05	2	140	2	15502373
Pubmed	Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.	APC NOTCH1	1.61e-05	2	140	2	22863622
Pubmed	Association analysis of polymorphic CGG repeat in 5' UTR of the reelin and VLDLR genes with schizophrenia.	VLDLR RELN	1.61e-05	2	140	2	12363388
Pubmed	Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	9922219
Pubmed	Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.	SFTPA2 SFTPA1	1.61e-05	2	140	2	34917085
Pubmed	A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation.	SFTPA2 SFTPA1	1.61e-05	2	140	2	23475791
Pubmed	Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).	APC GPA33	1.61e-05	2	140	2	12351151
Pubmed	Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.	SFTPA2 SFTPA1	1.61e-05	2	140	2	29394894
Pubmed	Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis.	KAT2A KAT2B	1.61e-05	2	140	2	11027331
Pubmed	RBX1 prompts degradation of EXO1 to limit the homologous recombination pathway of DNA double-strand break repair in G1 phase.	EXO1 RBX1	1.61e-05	2	140	2	31562368
Pubmed	Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function.	SFTPA2 SFTPA1	1.61e-05	2	140	2	19392648
Pubmed	Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.	SFTPA2 SFTPA1	1.61e-05	2	140	2	9126996
Pubmed	Abnormal splicing of the leptin receptor in diabetic mice.	PDE4B LEPR	1.61e-05	2	140	2	8628397
Pubmed	Effects of surfactant protein-A on the interaction of Pneumocystis murina with its host at different stages of the infection in mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	19335775
Pubmed	Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	33141765
Pubmed	DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation.	DOCK4 MUC2	1.61e-05	2	140	2	33559155
Pubmed	Innate immunity of surfactant protein A in experimental otitis media.	SFTPA2 SFTPA1	1.61e-05	2	140	2	31378117
Pubmed	Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.	SFTPA2 SFTPA1	1.61e-05	2	140	2	11237812
Pubmed	Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	27916681
Pubmed	Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway.	SFTPA2 SFTPA1	1.61e-05	2	140	2	12959932
Pubmed	Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition.	SFTPA2 SFTPA1	1.61e-05	2	140	2	15044702
Pubmed	Structural comparison of recombinant pulmonary surfactant protein SP-A derived from two human coding sequences: implications for the chain composition of natural human SP-A.	SFTPA2 SFTPA1	1.61e-05	2	140	2	1986781
Pubmed	Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation.	SFTPA2 SFTPA1	1.61e-05	2	140	2	12740217
Pubmed	Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse.	SFTPA2 SFTPA1	1.61e-05	2	140	2	18083768
Pubmed	The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue.	SFTPA2 SFTPA1	1.61e-05	2	140	2	35322074
Pubmed	Characteristics of surfactant from SP-A-deficient mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	9700084
Pubmed	Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population.	SFTPA2 SFTPA1	1.61e-05	2	140	2	20963503
Pubmed	Type IV pilus glycosylation mediates resistance of Pseudomonas aeruginosa to opsonic activities of the pulmonary surfactant protein A.	SFTPA2 SFTPA1	1.61e-05	2	140	2	25605768
Pubmed	Role of surfactant protein-A in nitric oxide production and mycoplasma killing in congenic C57BL/6 mice.	SFTPA2 SFTPA1	1.61e-05	2	140	2	12959946
Pubmed	Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.	KAT2A KAT2B	1.61e-05	2	140	2	25269644
Pubmed	Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells.	KAT2A KAT2B	1.61e-05	2	140	2	28678170
GeneFamily	Classical BAR domain containing	DNMBP ICA1L	7.97e-04	8	98	2	1292
GeneFamily	Collectins	SFTPA2 SFTPA1	1.27e-03	10	98	2	491
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	PDCD1 CD164 LAMP2 TNFRSF11A ITGAM LEPR ADGRE5 CLEC10A	1.35e-03	394	98	8	471
GeneFamily	Laminin subunits	LAMA2 LAMC1	1.85e-03	12	98	2	626
GeneFamily	ATAC complex	KAT2A KAT2B	2.18e-03	13	98	2	1058
GeneFamily	Low density lipoprotein receptors	VLDLR LRP1B	2.18e-03	13	98	2	634
GeneFamily	Lysine acetyltransferases\|ATAC complex\|SAGA complex\|GCN5 related N-acetyltransferases	KAT2A KAT2B	3.75e-03	17	98	2	1059
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT2A KAT2B	3.75e-03	17	98	2	486
Coexpression	CUI_TCF21_TARGETS_2_DN	ATG4A DOCK4 PDE4B LPAR4 ARID4A TRPC1 ASH1L ITPRID2 GAB2 BTBD3 ADGRL4 PTPN12 GIMAP8 MACF1 ELF1 ADGRE5 LRBA TASOR	6.59e-07	854	139	18	M1533
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK4 VLDLR ARID4A CENPF TRPC1 APC LAMC1 ARHGAP35 RLF PTPN12 NALF1 PHF3 MID1 MACF1 AKAP13 DNMBP TASOR TP53BP1	6.81e-07	856	139	18	M4500
Coexpression	WONG_ADULT_TISSUE_STEM_MODULE	VLDLR RELN ANK3 ASH1L LAMA2 DGKA LAMC1 GRIA2 ZFPM1 ARHGAP35 KMT2E ADGRL4 PTPN12 MACF1 ADGRE5 TP53BP1	1.49e-06	721	139	16	M1999
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	PDCD1 PDE4B NRDC ARID4A NOP53 ASH1L DGKA ICE1 ARHGAP35 KMT2E BIRC6 CARD8 KAT2B CSF1 GIMAP8 PHF3 MACF1 ELF1 AKAP13 ADGRE5 LRBA TASOR NOTCH1	3.73e-06	1492	139	23	M40023
Coexpression	CUI_TCF21_TARGETS_2_DN	DOCK4 PDE4B LPAR4 ARID4A TRPC1 ASH1L ITPRID2 GAB2 BTBD3 ADGRL4 PTPN12 GIMAP8 MACF1 ELF1 ADGRE5 LRBA TASOR	5.00e-06	888	139	17	MM1018
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN	ATG4A ATG16L1 APC DGKA TRAC CARD8 KAT2B DNMBP	1.07e-05	197	139	8	M3438
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	AKAP6 DOCK4 RELN ANK3 ARID4A APC GRIA2 ARHGAP35 KMT2E LRP1B DSCAML1 ZNF462 NALF1 MUC2 ICA1L UNC13A CALN1 DOP1A	2.34e-05	1106	139	18	M39071
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	PRUNE2 DPYS FRAS1 ANK3 ASH1L PKHD1 ULK4 AKAP13	2.46e-05	221	139	8	M39222
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	DOCK4 VLDLR ERBB3 CENPF ICE1 BTBD3 PHF3 ELF1 DOP1A	3.34e-05	300	139	9	M8702
Coexpression	BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP	LPAR4 ARID4A LAMA2 LAMC1 ITPRID2 KAT2B CSF1 PI4KB AKAP13 TASOR	4.51e-05	389	139	10	M6520
Coexpression	DESCARTES_FETAL_THYMUS_VASCULAR_ENDOTHELIAL_CELLS	DLGAP1 RELN TNFRSF11A PKHD1L1 ADGRL4 NALF1	7.24e-05	131	139	6	M40316
Coexpression	GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN	PPP4R1 GPR17 ASH1L NALF1 ULK4 C8A MUC2	8.18e-05	194	139	7	M8864
Coexpression	GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP	DPYS CEP192 PI4KB WASF2 EXO1 MACF1 MUC2	9.00e-05	197	139	7	M9569
Coexpression	GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN	PRUNE2 CENPF LAMC1 CFAP20DC CCDC3 PKHD1 ZNF443	9.29e-05	198	139	7	M9882
Coexpression	HALLMARK_MITOTIC_SPINDLE	DOCK4 CENPF APC CEP192 WASF2 MID1 AKAP13	9.59e-05	199	139	7	M5893
Coexpression	GSE3982_EOSINOPHIL_VS_BCELL_UP	FRAS1 GRIA2 LAMP2 ITPRID2 PKNOX2 ADGRE5 NOTCH1	9.59e-05	199	139	7	M5406
Coexpression	GSE31082_DN_VS_DP_THYMOCYTE_DN	ATG16L1 KMT2E BRWD3 RLF KAT2B PHF3 PI4KB	9.89e-05	200	139	7	M5055
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DLGAP2 RELN GRIA2 SI LRP1B EYS ADAMTS20 UNC13A CALN1	1.21e-09	150	140	9	0205318a870e091add66ee4305747dda9f51510d
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 DLGAP1 RELN DSCAML1 PKNOX2 MYO3A NALF1 PKHD1 SLC4A11	5.44e-09	178	140	9	544379f5a6145429762258d426b876bb36c112f5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FRAS1 RELN ABCA12 LRP1B PKHD1L1 DSCAML1 PKHD1 ADAMTS20	7.27e-09	184	140	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FRAS1 RELN ABCA12 LRP1B PKHD1L1 DSCAML1 PKHD1 ADAMTS20	7.27e-09	184	140	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FRAS1 RELN ABCA12 LRP1B PKHD1L1 DSCAML1 PKHD1 ADAMTS20	7.27e-09	184	140	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ABCA12 LAMA2 LRP1B PKHD1L1 DSCAML1 PKHD1 KLF18	4.30e-08	160	140	8	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ABCA12 LAMA2 LRP1B PKHD1L1 DSCAML1 PKHD1 KLF18	4.30e-08	160	140	8	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 DLGAP1 FRAS1 DSCAML1 MYO3A SLCO1A2 PKHD1 SLC4A11	6.28e-08	168	140	8	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 MGAM PDE4B TNFRSF11A ITGAM ZNF774 DDX60L GPA33	6.88e-08	170	140	8	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	DLGAP2 RELN TRPC1 TNFRSF11A PKHD1L1 KAT2B NALF1 GIMAP8	7.53e-08	172	140	8	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 DPYS FRAS1 ANK3 LRP1B MID1 PKHD1 ULK4	8.99e-08	176	140	8	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	AKAP6 TRMT9B PRUNE2 NALF1 HMCN2 MID1 CCDC3 ADGRE5	1.21e-07	183	140	8	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	AKAP6 TRMT9B PRUNE2 HMCN2 MID1 CCDC3 MACF1 ADGRE5	1.49e-07	188	140	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 ADGRL4 GIMAP8 NOTCH1	1.56e-07	189	140	8	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	AKAP6 TRMT9B PRUNE2 HMCN2 MID1 CCDC3 MACF1 ADGRE5	1.56e-07	189	140	8	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 DLGAP1 IP6K3 LAMA2 LAMC1 PKNOX2 ULK4 MACF1	1.83e-07	193	140	8	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	COVID-19-Fibroblasts-Mesothelial_FB\|COVID-19 / group, cell type (main and fine annotations)	DLGAP2 DPYS FRAS1 GRIA2 PKHD1L1 NALF1 CALN1	3.24e-07	141	140	7	7e6dcccb74e7ee90b69dc91b59491b84f3a713c9
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DLGAP2 RELN LRP1B MYO3A EYS ADAMTS20 CALN1	4.50e-07	148	140	7	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 RELN PDE4B TNFRSF11A PKHD1L1 GIMAP8 STARD9	1.14e-06	170	140	7	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 RELN PDE4B TNFRSF11A PKHD1L1 GIMAP8 STARD9	1.14e-06	170	140	7	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 RELN PDE4B TNFRSF11A PKHD1L1 GIMAP8 STARD9	1.14e-06	170	140	7	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB3 TRPC1 ZNF462 DDIAS ADAMTS20 TLE6 CALN1	1.50e-06	177	140	7	6b4fe717928814dafcd13090b1c90ea973938c6d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP1 DPYS FRAS1 LAMA2 LAMC1 PKNOX2 NALF1	1.74e-06	181	140	7	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC BIRC6 PHF3 WASF2 MACF1 ELF1 TASOR	1.94e-06	184	140	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN PDE4B TNFRSF11A PKHD1L1 GIMAP8	2.01e-06	185	140	7	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DPYS DSCAML1 ZNF462 MYO3A SLCO1A2 PKHD1	2.08e-06	186	140	7	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRMT9B PRUNE2 FRAS1 DSCAML1 SLCO1A2 PKHD1 RP1	2.16e-06	187	140	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 DPYS FRAS1 ANK3 LRP1B DSCAML1 PKHD1	2.16e-06	187	140	7	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 ADGRL4 DNMBP	2.32e-06	189	140	7	0d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 ZNF462 SLCO1A2 MID1 PKHD1 SLC4A11	2.32e-06	189	140	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AKAP6 DOCK4 DLGAP1 DPYS FRAS1 LAMA2 NALF1	2.32e-06	189	140	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4B ANK3 DGKA TRAC PHF3 MACF1 LRBA	2.40e-06	190	140	7	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 KIZ NALF1 MID1 PLCL2 ULK4	2.40e-06	190	140	7	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 ASH1L PKHD1 MACF1 AKAP13 LRBA	2.57e-06	192	140	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 TRMT9B ANK3 CACHD1 ARMC2 RP1 ICA1L	2.66e-06	193	140	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK4 PKHD1L1 LEPR ADGRL4 BMPR2 NALF1 RP1	2.66e-06	193	140	7	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ANK3 LRP1B DSCAML1 PKHD1 RP1 LRBA	2.85e-06	195	140	7	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DLGAP2 RELN GRIA2 LRP1B EYS CALN1	3.24e-06	128	140	6	91072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASH1L KMT2E BIRC6 PHF3 MACF1 AKAP13 DDX60L	3.37e-06	200	140	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ASH1L ITPRID2 BIRC6 LEPR BMPR2 MACF1 NOTCH1	3.37e-06	200	140	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19-kidney-Epithelial_Doublet\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRP1B DSCAML1 EYS PKHD1 ADAMTS20 CALN1	3.54e-06	130	140	6	1ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCell	COVID-19_Mild-Neu_2\|World / 5 Neutrophil clusters in COVID-19 patients	ERBB3 LPAR4 ANK3 NOP53 MYO3A NAGPA	5.43e-06	140	140	6	b1429028c52f84127b894b93b55961badcd5246f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 IP6K3 DSCAML1 PKHD1 ULK4 RP1	6.13e-06	143	140	6	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	COVID-19-kidney-Technical/muscle\|kidney / Disease (COVID-19 only), tissue and cell type	DLGAP2 RELN LPAR4 EYS EXO1 CALN1	7.47e-06	148	140	6	0dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIZ TRAC ARHGAP35 SARS2 NALF1 LRBA	1.13e-05	159	140	6	03d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	AKAP6 DLGAP1 GRIA2 LRP1B ZNF774 SLCO1A2	1.21e-05	161	140	6	347edb0de10850b7d16c40945751033289289c9b
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	DLGAP2 RELN PDE4B TNFRSF11A PKHD1L1 GIMAP8	1.49e-05	167	140	6	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ABCA12 LRP1B PKHD1L1 PKHD1 RP1	1.59e-05	169	140	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DLGAP2 RELN SI EYS UNC13A CALN1	1.70e-05	171	140	6	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 DLGAP1 PKNOX2 LY6D MYO3A SLC4A11	1.76e-05	172	140	6	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A GAB2 KCNRG MACF1 AKAP13 TASOR	1.82e-05	173	140	6	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A GAB2 KCNRG MACF1 AKAP13 TASOR	1.82e-05	173	140	6	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A GAB2 KCNRG MACF1 AKAP13 TASOR	1.82e-05	173	140	6	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	Adult-Epithelial-basal_cell-D231\|Adult / Lineage, Cell type, age group and donor	TRMT9B FRAS1 ABCA12 CACHD1 MYO3A SLC4A11	1.88e-05	174	140	6	a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLGAP2 RELN ZFPM1 FBXO10 GIMAP8 NOTCH1	1.94e-05	175	140	6	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 BTBD3 LY6D LYPD8 GPA33 CALN1	1.94e-05	175	140	6	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A GAB2 KCNRG MACF1 AKAP13 TASOR	1.94e-05	175	140	6	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 ZNF462 SLCO1A2 PKHD1 SLC4A11	2.00e-05	176	140	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DLGAP2 RELN TNFRSF11A PKHD1L1 ADGRL4 GIMAP8	2.20e-05	179	140	6	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DLGAP2 RELN TNFRSF11A PKHD1L1 ADGRL4 GIMAP8	2.20e-05	179	140	6	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 NALF1	2.20e-05	179	140	6	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 SI TNFRSF11A MALRD1 LYPD8 GPA33	2.27e-05	180	140	6	7c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 MIOX DSCAML1 PNPLA1 CCDC3 CALN1	2.34e-05	181	140	6	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 DPYS FRAS1 LRP1B DSCAML1 PKHD1	2.42e-05	182	140	6	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 ZNF462 SLCO1A2 PKHD1 SLC4A11	2.42e-05	182	140	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	AKAP6 TRMT9B PRUNE2 HMCN2 CCDC3 ADGRE5	2.49e-05	183	140	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 ZNF462 SLCO1A2 PKHD1 SLC4A11	2.49e-05	183	140	6	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	VLDLR ANK3 BMPR2 PTPN12 MACF1 DNMBP	2.49e-05	183	140	6	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 NOTCH1	2.49e-05	183	140	6	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRMT9B DLGAP2 RELN PDE4B TNFRSF11A PKHD1L1	2.57e-05	184	140	6	30ca56d64c961127e26122613e35aa2b46fde2df
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	ERBB3 ANK3 CACHD1 SFTPA2 SFTPA1 RP1	2.65e-05	185	140	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DLGAP2 RELN TNFRSF11A PKHD1L1 ADGRL4 GIMAP8	2.65e-05	185	140	6	3be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	ANK3 NRDC USP11 ICE1 KMT2E MID1	2.65e-05	185	140	6	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DLGAP2 RELN TNFRSF11A PKHD1L1 ADGRL4 GIMAP8	2.65e-05	185	140	6	c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKA LY6D WASF2 MACF1 ELF1 TASOR	2.73e-05	186	140	6	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DLGAP1 FRAS1 DSCAML1 PKHD1 RP1	2.73e-05	186	140	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ARID4A APC BIRC6 LIN9 BRWD3 BMPR2	2.73e-05	186	140	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ERBB3 DSCAML1 MID1 PKHD1 C8A LRBA	2.81e-05	187	140	6	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DOCK4 FRAS1 LAMA2 PKNOX2 ULK4 MACF1	2.81e-05	187	140	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	GPR17 LEPR ADGRL4 BMPR2 GIMAP8 CALN1	2.81e-05	187	140	6	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRMT9B FRAS1 LRP1B DSCAML1 NALF1 PKHD1	2.90e-05	188	140	6	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ASH1L BIRC6 RLF MACF1 LRBA TP53BP1	2.90e-05	188	140	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 DSCAML1	2.90e-05	188	140	6	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 ZNF462 SLCO1A2 PKHD1 SLC4A11	2.90e-05	188	140	6	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 ANK3 KIZ LRP1B MID1 PKHD1	2.90e-05	188	140	6	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	390C-Lymphocytic-CD4_T-cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	PDCD1 PDE4B NOP53 DGKA TRAC ELF1	2.90e-05	188	140	6	0da6d6d3c28e9d99159b1a24a345a2250e8e1995
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 DSCAML1	2.90e-05	188	140	6	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164 LAMP2 ITGAM WASF2 MID1 MACF1	2.99e-05	189	140	6	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	USP11 ITPRID2 KAT2A FH ICA1L DOP1A	2.99e-05	189	140	6	8b6f92ccfffc743c07201bc971b3dc1a6fa14ccc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 CACHD1 LRP1B NALF1 PKHD1 LRBA	2.99e-05	189	140	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	PKHD1L1 LEPR ADGRL4 BMPR2 PTPN12 NALF1	2.99e-05	189	140	6	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164 LAMP2 ITGAM WASF2 MID1 MACF1	2.99e-05	189	140	6	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|COVID-19_Convalescent / Disease condition and Cell class	USP11 ITPRID2 KAT2A FH ICA1L DOP1A	2.99e-05	189	140	6	732e8dcffcb634ca2968f9170c9c4b31dd5d4206
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164 LAMP2 ITGAM WASF2 MID1 MACF1	2.99e-05	189	140	6	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164 LAMP2 ITGAM WASF2 MID1 MACF1	2.99e-05	189	140	6	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRMT9B PRUNE2 FRAS1 DSCAML1 PKHD1 RP1	3.08e-05	190	140	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRMT9B DLGAP2 RELN TNFRSF11A PKHD1L1 GIMAP8	3.08e-05	190	140	6	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	wk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TRMT9B RELN TNFRSF11A PKHD1L1 ADGRL4 GIMAP8	3.08e-05	190	140	6	279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRMT9B DLGAP2 RELN LAMC1 PKHD1L1 DSCAML1	3.08e-05	190	140	6	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MRPL44 LAMA2 LAMC1 CSF1 TLE6 ADGRE5	3.08e-05	190	140	6	048b581e3f7ea9fc2f87c0532974bba85c7292c2
Disease	Schizophrenia	DOCK4 DLGAP2 VLDLR DLGAP1 ERBB3 RELN PDE4B ANK3 APC LAMA2 GRIA2 ITGAM PKNOX2 PLCL2 FADS2 ULK4	3.66e-06	883	137	16	C0036341
Disease	Manic Disorder	RELN PDE4B ANK3 STARD9 FADS2	2.04e-05	71	137	5	C0024713
Disease	Manic	RELN PDE4B ANK3 STARD9 FADS2	3.22e-05	78	137	5	C0338831
Disease	Depression, Bipolar	RELN PDE4B ANK3 STARD9 FADS2	3.43e-05	79	137	5	C0005587
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	FADS2 MACF1 LRBA CLEC10A CALN1 TP53BP1	7.42e-05	150	137	6	EFO_0004611, EFO_0020947
Disease	Abnormality of refraction	AKAP6 ANK3 LAMA2 BIRC6 DSCAML1 ZNF462 ADAMTS20 ULK4 AKAP13 CALN1 SLC4A11 RBX1	7.47e-05	673	137	12	HP_0000539
Disease	Bipolar Disorder	ERBB3 RELN PDE4B ANK3 GRIA2 ITGAM STARD9 FADS2 ULK4 CLEC10A	8.17e-05	477	137	10	C0005586
Disease	Myopia	AKAP6 DLGAP2 FRAS1 LAMA2 DSCAML1 ULK4 AKAP13 DDX60L CLEC10A	8.24e-05	385	137	9	HP_0000545
Disease	PR interval	AKAP6 DOCK4 ARID4A ABCA12 LAMC1 ZFPM1 MYO3A BMPR2 FADS2 MACF1	1.11e-04	495	137	10	EFO_0004462
Disease	smoking cessation	PDE4B ANK3 BIRC6 LEPR PLCL2 ICA1L CALN1 RBX1	1.45e-04	325	137	8	EFO_0004319
Disease	level of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum	SFTPA2 SFTPA1	2.12e-04	5	137	2	OBA_2042200
Disease	Congenital ichthyosis	ABCA12 PNPLA1	2.12e-04	5	137	2	C0020758
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 EYS	2.12e-04	5	137	2	EFO_0004647, EFO_0006952
Disease	level of prosaposin in blood serum	SFTPA2 SFTPA1	2.12e-04	5	137	2	OBA_2044552
Disease	cortical thickness	AKAP6 TRMT9B ERBB3 RELN LAMA2 LAMC1 ARHGAP35 ZNF462 MALRD1 NALF1 SLCO1A2 PKHD1 ADAMTS20 FADS2 MACF1	2.14e-04	1113	137	15	EFO_0004840
Disease	Autistic Disorder	DOCK4 DLGAP2 VLDLR RELN PDE4B APC KMT2E	2.26e-04	261	137	7	C0004352
Disease	red blood cell density measurement	VLDLR LAMC1 ADGRL4 ZNF462 KAT2B PNPLA1 GIMAP8 PLCL2 PKHD1 FADS2 ULK4 AKAP13 TASOR	2.41e-04	880	137	13	EFO_0007978
Disease	severe acute respiratory syndrome, COVID-19	TRMT9B DLGAP2 DLGAP1 RELN LRP1B EYS MALRD1 FBXO10 NALF1	2.52e-04	447	137	9	EFO_0000694, MONDO_0100096
Disease	cholesteryl ester 14:0 measurement	CARD8 FADS2 FH	2.64e-04	27	137	3	EFO_0010340
Disease	alkaline phosphatase measurement	ATG16L1 TNFRSF11A ZFPM1 LEPR MYO3A FADS2 MACF1 ELF1 AKAP13 RP1 LRBA CLEC10A NOTCH1 TP53BP1	2.78e-04	1015	137	14	EFO_0004533
Disease	newborn respiratory distress syndrome (biomarker_via_orthology)	SFTPA2 SFTPA1	3.17e-04	6	137	2	DOID:12716 (biomarker_via_orthology)
Disease	level of Phosphatidylcholine (18:0_20:2) in blood serum	EXO1 FADS2	3.17e-04	6	137	2	OBA_2045092
Disease	anorexia nervosa	AKAP6 ERBB3 ADGRL4 NALF1	3.22e-04	70	137	4	MONDO_0005351
Disease	cognitive function measurement	AKAP6 PPP4R1 IL20RB CEP192 KMT2E BIRC6 LRP1B ADGRL4 MYO3A NALF1 PLCL2 PKHD1 ZNF799 MUC2 ZNF443 CALN1 RBX1	3.62e-04	1434	137	17	EFO_0008354
Disease	verbal-numerical reasoning measurement	AKAP6 ERBB3 BIRC6 PLCL2 CALN1	3.74e-04	131	137	5	EFO_0008394
Disease	newborn respiratory distress syndrome (is_implicated_in)	SFTPA2 SFTPA1	4.43e-04	7	137	2	DOID:12716 (is_implicated_in)
Disease	Rectal Neoplasms	APC MUC2	4.43e-04	7	137	2	C0034885
Disease	1-eicosatrienoylglycerophosphocholine measurement	SLCO1A2 FADS2	4.43e-04	7	137	2	EFO_0021081
Disease	Rectal Carcinoma	APC MUC2	4.43e-04	7	137	2	C0007113
Disease	neuroimaging measurement	ERBB3 RELN ANK3 APC LAMA2 LAMC1 ARHGAP35 ZNF462 NALF1 PKHD1 ADAMTS20 FADS2 MACF1 ICA1L	4.67e-04	1069	137	14	EFO_0004346
Disease	Malignant neoplasm of breast	AKAP6 ERBB3 CENPF LAMA2 LEPR BMPR2 CSF1 EXO1 MACF1 LRBA SPOCD1 NOTCH1 TP53BP1 DOP1A	4.89e-04	1074	137	14	C0006142
Disease	age at menopause	MGAM SRPK1 ZFPM1 BIRC6 GAB2 BMPR2 EXO1	5.43e-04	302	137	7	EFO_0004704
Disease	otosclerosis	DPYS RELN IP6K3 CSF1	5.61e-04	81	137	4	EFO_0004213
Disease	2-arachidonoyl-GPE (20:4) measurement	SLCO1A2 FADS2	5.88e-04	8	137	2	EFO_0800260
Disease	1-linoleoyl-GPE (18:2) measurement	SLCO1A2 FADS2	5.88e-04	8	137	2	EFO_0800247
Disease	leukocyte immunoglobulin-like receptor subfamily B member 4 measurement	SFTPA2 SFTPA1	5.88e-04	8	137	2	EFO_0801768
Disease	human immunodeficiency virus infectious disease (is_marker_for)	PDCD1 KMT2E LEPR	6.25e-04	36	137	3	DOID:526 (is_marker_for)
Disease	mean corpuscular hemoglobin concentration	ARID4A SRPK1 ZFPM1 LIN9 LEPR ADGRL4 KAT2B BMPR2 PLCL2 EXO1 FADS2 MACF1 ELF1 AKAP13	6.46e-04	1105	137	14	EFO_0004528
Disease	autism spectrum disorder (implicated_via_orthology)	TRPC1 ASH1L LAMC1 DSCAML1 LRBA	7.35e-04	152	137	5	DOID:0060041 (implicated_via_orthology)
Disease	Gastrointestinal Hemorrhage	RELN APC	7.54e-04	9	137	2	C0017181
Disease	Osteitis Deformans	TNFRSF11A CSF1	7.54e-04	9	137	2	C0029401
Disease	Colon Carcinoma	ERBB3 PTPN12	7.54e-04	9	137	2	C0699790
Disease	body surface area	ERBB3 PDE4B KIZ ZNF462 PKHD1 ULK4 MACF1 AKAP13 TASOR CALN1	8.68e-04	643	137	10	EFO_0022196
Disease	testosterone measurement	DOCK4 DLGAP1 PDE4B ANK3 NRDC BIRC6 LEPR PKNOX2 KAT2B NALF1 SLCO1A2 MACF1 ZNF799 DNMBP SPOCD1	8.81e-04	1275	137	15	EFO_0004908
Disease	rectum cancer	DLGAP2 LAMC1 LRP1B	9.85e-04	42	137	3	EFO_1000657
Disease	aspartate aminotransferase measurement	ERBB3 ARHGAP35 BIRC6 LEPR GAB2 PKNOX2 CSF1 HMCN2 ELF1 AKAP13 LRBA DNMBP	1.07e-03	904	137	12	EFO_0004736
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	ABCA12 PNPLA1	1.15e-03	11	137	2	C0079154
Disease	Congenital ichthyosis of skin	ABCA12 PNPLA1	1.15e-03	11	137	2	cv:C0020758
Disease	serum gamma-glutamyl transferase measurement	ASH1L ZFPM1 ARHGAP35 KAT2B EYS SLCO1A2 PKHD1 AKAP13 RP1 LRBA DNMBP TP53BP1	1.17e-03	914	137	12	EFO_0004532
Disease	Intellectual Disability	AKAP6 ASH1L APC GRIA2 KMT2E BRWD3 ZNF462 MACF1	1.19e-03	447	137	8	C3714756
Disease	schizophrenia, intelligence, self reported educational attainment	AKAP6 ERBB3 IP6K3 KMT2E LRP1B PLCL2 CALN1	1.20e-03	346	137	7	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	neuritic plaque measurement	DLGAP2 ANK3 IL20RB ICE1 NALF1 RP1 ZNF443	1.26e-03	349	137	7	EFO_0006798
Disease	ficolin-3 measurement	WASF2 RP1	1.37e-03	12	137	2	EFO_0020392
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	SFTPA2 SFTPA1	1.37e-03	12	137	2	EFO_0801493
Disease	granulins measurement	SFTPA2 SFTPA1	1.37e-03	12	137	2	EFO_0008141
Disease	Intestinal Neoplasms	APC MUC2	1.37e-03	12	137	2	C0021841
Disease	Intestinal Cancer	APC MUC2	1.37e-03	12	137	2	C0346627
Disease	autistic disorder (is_marker_for)	VLDLR RELN	1.37e-03	12	137	2	DOID:12849 (is_marker_for)
Disease	cognitive function measurement, self reported educational attainment	AKAP6 IL20RB BIRC6 PKHD1 ZNF799 ZNF443 CALN1	1.39e-03	355	137	7	EFO_0004784, EFO_0008354
Disease	rheumatoid arthritis	DLGAP2 DLGAP1 ERBB3 TNFRSF11A ZNF774 CFAP20DC PLCL2 FADS2	1.46e-03	462	137	8	EFO_0000685
Disease	osteitis deformans	DPYS TNFRSF11A	1.61e-03	13	137	2	EFO_0004261
Disease	dihomo-linolenoylcarnitine (C20:3n3 or 6) measurement	SLCO1A2 FADS2	1.61e-03	13	137	2	EFO_0800547
Disease	gallbladder cancer (is_implicated_in)	APC LRP1B	1.61e-03	13	137	2	DOID:3121 (is_implicated_in)
Disease	serum albumin measurement	DOCK4 ZFPM1 KAT2A ARMC2 LEPR CSF1 FADS2 MACF1 TP53BP1	1.83e-03	592	137	9	EFO_0004535
Disease	Hamman-Rich syndrome	SFTPA2 SFTPA1	1.88e-03	14	137	2	C0085786
Disease	lysophosphatidylcholine 15:0 measurement	LRP1B PKHD1	1.88e-03	14	137	2	EFO_0020941
Disease	bacterial pneumonia (biomarker_via_orthology)	SFTPA2 SFTPA1	1.88e-03	14	137	2	DOID:874 (biomarker_via_orthology)
Disease	IGFBP-3 measurement	DLGAP1 ERBB3 PKNOX2	2.04e-03	54	137	3	EFO_0004626
Disease	Down syndrome (implicated_via_orthology)	DSCAML1 DOP1A	2.16e-03	15	137	2	DOID:14250 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERBB3 NOTCH1	2.16e-03	15	137	2	C0496930
Disease	Benign neoplasm of bladder	ERBB3 NOTCH1	2.16e-03	15	137	2	C0154017
Disease	Carcinoma in situ of bladder	ERBB3 NOTCH1	2.16e-03	15	137	2	C0154091
Disease	anemia (implicated_via_orthology)	APC SLC4A11	2.16e-03	15	137	2	DOID:2355 (implicated_via_orthology)
Disease	body weight	AKAP6 MGAM RELN PDE4B KIZ CEP192 LRP1B KCNRG EYS PHF3 FADS2 ULK4 CLEC10A CALN1	2.25e-03	1261	137	14	EFO_0004338
Disease	vascular endothelial growth factor measurement	VLDLR ZFPM1 ZNF462	2.27e-03	56	137	3	EFO_0004762
Disease	creatinine measurement	CENPF USP11 TRPC1 LAMA2 BIRC6 BRWD3 GAB2 KAT2B PTPN12 PKHD1 FADS2 FH	2.38e-03	995	137	12	EFO_0004518
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	LEPR FADS2 MACF1 TASOR CALN1 TP53BP1	2.44e-03	291	137	6	EFO_0008317, EFO_0020946
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	GAB2 MACF1 CALN1 TP53BP1	2.48e-03	121	137	4	EFO_0008595, EFO_0020943
Disease	eosinophil percentage of leukocytes	PDCD1 ZFPM1 LEPR PLCL2 EXO1 FADS2 ELF1 AKAP13 MUC2 RBX1	2.59e-03	746	137	10	EFO_0007991
Disease	creatine kinase measurement	AKAP6 GAB2 CSF1	2.63e-03	59	137	3	EFO_0004534
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	AKAP6 KIZ IL20RB PLCL2 ZNF799 ZNF443 CALN1	2.65e-03	398	137	7	EFO_0003756, EFO_0003888, EFO_0004337
Disease	hematocrit	VLDLR ASH1L ZFPM1 ADGRL4 ZNF462 PNPLA1 PLCL2 PKHD1 FADS2 ULK4 TASOR TP53BP1	2.71e-03	1011	137	12	EFO_0004348
Disease	Benign neoplasm of stomach	ERBB3 APC	2.78e-03	17	137	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB3 APC	2.78e-03	17	137	2	C0496905
Disease	Antibody Deficiency Syndrome	LEPR C8A	2.78e-03	17	137	2	C0003257
Disease	Lipidemias	APC LEPR	2.78e-03	17	137	2	C1706412
Disease	Carcinoma in situ of stomach	ERBB3 APC	2.78e-03	17	137	2	C0154060
Disease	pre-eclampsia (biomarker_via_orthology)	PDCD1 LEPR	2.78e-03	17	137	2	DOID:10591 (biomarker_via_orthology)
Disease	Hyperlipidemia	APC LEPR	2.78e-03	17	137	2	C0020473
Disease	puberty onset measurement	DLGAP1 IL20RB BIRC6 LEPR	2.79e-03	125	137	4	EFO_0005677
Disease	retinal vasculature measurement	PDE4B LAMA2 IL20RB LAMC1 DSCAML1 KAT2B EYS UNC13A	2.94e-03	517	137	8	EFO_0010554
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	FADS2 MACF1 CALN1 TP53BP1	2.96e-03	127	137	4	EFO_0008595, EFO_0020947
Disease	lysophosphatidylcholine measurement	MGAM SRBD1 FADS2	3.03e-03	62	137	3	EFO_0010224
Disease	Malignant Neoplasms	ERBB3 APC BIRC6 NOTCH1	3.04e-03	128	137	4	C0006826
Disease	mood instability measurement	LAMC1 LRP1B EYS PLCL2	3.04e-03	128	137	4	EFO_0008475
Disease	lupus nephritis (is_implicated_in)	PDCD1 ITGAM	3.12e-03	18	137	2	DOID:0080162 (is_implicated_in)
Disease	Carcinoma of bladder	ERBB3 NOTCH1	3.12e-03	18	137	2	C0699885
Disease	respiratory syncytial virus infectious disease (is_marker_for)	PDCD1 SFTPA1	3.12e-03	18	137	2	DOID:1273 (is_marker_for)
Disease	disease free survival	TRMT9B ICE1	3.12e-03	18	137	2	EFO_0000409
Disease	chronic obstructive pulmonary disease (is_implicated_in)	LRP1B LEPR SFTPA1	3.17e-03	63	137	3	DOID:3083 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SCSVVDVFSQLNQSF	UNC13A	1186	Q9UPW8
TQSCGENANCTNTEG	ADGRL4	66	Q9HBW9
QTVDSSNIDGFVNCT	ERBB3	341	P21860
NEGTCIQQDSFSSSE	ASH1L	496	Q9NR48
ENGTVNDQTFHCLQS	ATG4A	291	Q8WYN0
NVQTICNGTVSVASS	ELF1	511	P32519
CERESANGFETNVAS	ARID4A	1041	P29374
GSTDNESCTNSELNS	BIRC6	606	Q9NR09
SSTTCVRQAQCGQDF	C8A	86	P07357
VFAGSSCNDIVCTEQ	ATG16L1	446	Q676U5
ITNFGVCSCSENVQE	ABCA12	1841	Q86UK0
NITNASSCFGNEDTN	ARMC2	791	Q8NEN0
TNFSLATAEQCGQET	GPR17	41	Q13304
CEFVGSENNSVTVEG	FBXO10	246	Q9UK96
GQHQCDSSTVCFNTV	ADGRE5	216	P48960
ACQQNTVTSSGDLVA	AKAP13	666	Q12802
GTNAFVGIVNETCDS	CACHD1	931	Q5VU97
CQNSGVQEDSDSSSE	BRWD3	811	Q6RI45
VQFQCSSDSTNGTGV	BTBD3	496	Q9Y2F9
VNGQFESVCESVFSE	DLGAP1	456	O14490
NGQFESVCESVFSEV	DLGAP2	536	Q9P1A6
NACSQASDFSVQSVA	DOP1A	796	Q5JWR5
SVSSGNQDDCIVNGE	DNMBP	211	Q6XZF7
LNETSGNCQTEFEGV	CALN1	206	Q9BXU9
IVVTADSSQCANNCG	ADAMTS20	1591	P59510
CQANQASATSEECTV	RBX1	56	P62877
VSTNAIFDNSTDSCV	RAD51AP2	76	Q09MP3
QGFTEIVFCAVTSNE	KAT2A	571	Q92830
GNVNGCSTAEESVSQ	ANKRD13A	426	Q8IZ07
FSSQLTATCNVEQSF	FADS2	356	O95864
QAATQESTFQELCEG	NOP53	286	Q9NZM5
VQASSQCFQSATDVA	NOTCH1	1686	P46531
RCSEAGINQTSVQFS	FRAS1	3211	Q86XX4
ADNQLLDENGTTCTF	LRP1B	821	Q9NZR2
TIDASNISCFQNNVE	LIN9	501	Q5TKA1
QQFCQESLSSEFCSG	EYS	171	Q5T1H1
CTSSNEEGTQFCNIT	GPA33	211	Q99795
QGFTEIVFCAVTSNE	KAT2B	566	Q92831
TVSDCQVGNTTDFCS	CD164	96	Q04900
QVGNTTDFCSVSTAT	CD164	101	Q04900
SAQDAGAYVCTATNT	HMCN2	1036	Q8NDA2
AQAGTYTCVAENTQA	HMCN2	3196	Q8NDA2
FSTTNVNNATTTCFE	LPAR4	176	Q99677
NEVSNFVDGSVSGCS	MGAM	531	O43451
ANDDLTTTGTDNCTF	DPYS	316	Q14117
TTTGTDNCTFNTCQK	DPYS	321	Q14117
NIDVQTEFSGCLSQD	DDX60L	116	Q5H9U9
EVANSFAVTNAFCSQ	GRIA2	66	P42262
EGDNATFTCSFSNTS	PDCD1	46	Q15116
SSSSQQNNTVLVEGC	MUC2	4781	Q02817
AITTVSQECFDVENG	PDE4B	86	Q07343
NFENSQDFVPCSQST	DDIAS	761	Q8IXT1
GATCFECEITFSNVN	ZFPM1	576	Q8IX07
QSFETGHCLNETNVT	DGKA	76	P23743
DAITISTFSGQQDIC	PNPLA1	186	Q8N8W4
ATVYNATSEETSNNC	KMT2E	1221	Q8IZD2
QSCTETGSENENVSL	LRBA	1561	P50851
GSVCISDQFNSVNFS	LEPR	951	P48357
FVQNGTVSTNEFLCD	LAMP2	176	P13473
NCSTVGSLDFQCNVN	LAMA2	1061	P24043
LVFQCGSDSTTDNQT	KCNRG	176	Q8N5I3
QTAQSSNVTDSCVVQ	KIZ	196	Q2M2Z5
SGSQDFPQCNTIENT	ITPRID2	591	P28290
QQTTGSNGSDCTLAQ	IP6K3	111	Q96PC2
SAFSQTECVEVQGEA	IL20RB	216	Q6UXL0
TSFTCQNEQAHTLET	MACF1	2171	Q9UPN3
IQFEINVGCSTDSSS	RELN	2021	P78509
AQQGTESFQCDNGVS	MALRD1	31	Q5VYJ5
NVEKQSSSGTNCSSD	ICE1	281	Q9Y2F5
SIEQSSNCEAETTFQ	ICE1	1381	Q9Y2F5
SNCEAETTFQCQIAT	ICE1	1386	Q9Y2F5
CPQEDVSSSGQSTNF	ICE1	1491	Q9Y2F5
RCSTSETSGFENQVN	DOCK4	1856	Q8N1I0
CNNSFAECSSQDVVT	CSF1	171	P09603
VSANQCSVDEVFCSS	CENPF	1516	P49454
SNCSQGQQLATFSSD	CCDC3	161	Q9BQI4
DAEFSQAVNPQSFCT	DSCAML1	1686	Q8TD84
ASVSFTENCVVGIQA	FH	426	P07954
TEGSRFQDCVNEAAS	GIMAP8	206	Q8ND71
ISTESLDCEVNNNGS	BMPR2	991	Q13873
TGIFFQAEACVTNDT	CARD8	56	Q9Y2G2
GNNDQSITECSIATT	ANK3	3386	Q12955
QNETSSGNLESCAQA	ANK3	4201	Q12955
QVSSGTSSTQCCQED	LY6D	76	Q14210
SNVSNATCQFLSGEN	LYPD8	171	Q6UX82
FSGQVSHQTTSENQC	CEP192	1211	Q8TEP8
SDNQTLCGDQVTFSS	KLF18	176	A0A0U1RQI7
NAAFNVTVVATNTCG	LAMC1	56	P11047
TSEFTQECQTAFGSP	ICA1L	361	Q8NDH6
EQATQGSECITSASF	PKNOX2	91	Q96KN3
ETSVVNCSNNSFSGN	RP1	941	P56715
QASVVFCDSTFQDNP	MIOX	151	Q9UGB7
SICQICGFNQAEEST	GAB2	111	Q9UQC2
CGFNQAEESTDSLRN	GAB2	116	Q9UQC2
ITNCSGVTVVFENND	GARIN2	281	Q8N9W8
FGEVTSASNCTDFQS	SARS2	416	Q9NP81
SEQGTSFSQTCLTQF	MRPL44	126	Q9H9J2
QATNTENEATSGGCV	SLC4A11	76	Q8NBS3
HAEENSCVTSNVSTN	PRUNE2	1976	Q8WUY3
SCVTSNVSTNEGQET	PRUNE2	1981	Q8WUY3
NFGDICSVVGQQATE	PPP4R1	236	Q8TF05
NGISDQISEDCAFSV	PLCL2	206	Q9UPR0
SQATECDETQETGSF	NAGPA	216	Q9UK23
NVGDTSQNSCVDCSV	PTPN12	486	Q05209
CDVETQSFQGNVSLS	PKHD1	1336	P08F94
FQNCSCIQTSGNSSA	SLCO1A2	481	P46721
NEPSSFVNGTTTNQC	SI	1396	P14410
SNGQSITFDAIQEAC	SFTPA2	141	Q8IWL1
VCQSSSTVGQSFSEQ	SRPK1	426	Q96SB4
HFESQSVTCDVQNST	STARD9	2811	Q9P2P6
GNDNICQDDLSITFS	ITGAM	771	P11215
TNSCDNISQFSVDSI	PI4KB	476	Q9UBF8
DSGSCSALQNEFVSE	SFR1	131	Q86XK3
NAAEACSTTEEVFNS	ARHGAP35	956	Q9NRY4
ACSSQSQESGEFSLQ	EXO1	671	Q9UQ84
SNGQSITFDAIQEAC	SFTPA1	141	Q8IWL2
FCSQQTETSGQIQGV	SRBD1	776	Q8N5C6
VCLFTDFDSQTNVSQ	TRAC	21	P01848
IVCSEGENSNSTEQD	TASOR	1576	Q9UK61
GTEENASISNISCCN	AKAP6	2026	Q13023
SSAEDEIGCNQTTQE	APC	1281	P25054
EIGCNQTTQEADSAN	APC	1286	P25054
QVDNCNVSISTSSDD	CFAP20DC	576	Q6ZVT6
QVATLNNNASTEGTC	CLEC10A	166	Q8IUN9
CEQQSNDTFHSFIGT	TRPC1	576	P48995
FCAESANSQIDTETA	RLF	871	Q13129
ATECNCSLGNFDSQV	SLC27A4	386	Q6P1M0
VCLFTDFDSQTNVSQ	TRA	156	P0DTU3
GASAQASAEQQEAVC	SPOCD1	331	Q6ZMY3
QDNSETAEQCGTSSE	ZNF774	81	Q6NX45
FTGQANVVSLCNSAD	MID1	421	O15344
DGTQCGETSSQIQDS	ZNF799	76	Q96GE5
GSDNASTDCERTVFQ	NRDC	261	O43847
DGNVSCSENLVANTA	PHF3	1626	Q92576
NVCEQGTSTVDQNFG	TP53BP1	1176	Q12888
SNNGTGAEQACEVSV	PKHD1L1	2056	Q86WI1
FLACCSQDAQGQETT	TOP3A	441	Q13472
GESNSVTCNCGQEAV	TOP3A	806	Q13472
QNGSIGCVENVDASS	WASF2	231	Q9Y6W5
LQFAADAEVSTVSNC	XNDC1N	206	Q6ZNB5
DGTQCGETSSQIQDS	ZNF443	76	Q9Y2A4
DSTNTGVNCVDAGNI	TRMT9B	351	Q9P272
CGSVNASNQTEVEFS	ZNF462	46	Q96JM2
VQEGEDFTTYCNSST	TRAV25	31	A0A0B4J276
DQDSSTFPGCINNAT	USP11	121	P51784
IVESCSQLQGFQSEE	TLE6	81	Q9H808
NVCTTFSAQSQGFIT	ULK4	631	Q96C45
GENDSLSQCFTGTQS	TNFRSF11A	381	Q9Y6Q6
NVEENGRDCQSTATT	VLDLR	741	P98155
ASSGQCFTVENADAV	NALF1	176	B1AL88
EAFGNACTIINDNSS	MYO3A	471	Q8NEV4